#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:F1PAA9 uniprotkb:Q96EB1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3951755|uniprotkb:Q9H4E8|uniprotkb:Q9NX11|uniprotkb:B4E3W0|uniprotkb:E7EPZ6|ensembl:ENSP00000492152 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:elp4_human(display_long)|uniprotkb:ELP4(gene name)|psi-mi:ELP4(display_short)|uniprotkb:C11orf19(gene name synonym)|uniprotkb:PAXNEB(gene name synonym)|uniprotkb:PAX6 neighbor gene protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_061913.3|refseq:NP_001275654.1|refseq:NP_001275655.1|ensembl:ENSG00000109911(gene)|ensembl:ENST00000640961(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006368"(transcription elongation from RNA polymerase II promoter)|go:"GO:0008023"(transcription elongation factor complex)|go:"GO:0008607"(phosphorylase kinase regulator activity)|go:"GO:0033588"(elongator holoenzyme complex)|interpro:IPR008728(PAXNEB)|interpro:IPR027417|reactome:R-HSA-3214847|go:"GO:0002098"(tRNA wobble uridine modification) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6z423L9MZoYVOp4bvmr9xsVA35w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95297 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-963338|ensembl:ENSP00000352513|uniprotkb:Q5R332|uniprotkb:Q8IX11|uniprotkb:Q9BWZ3|uniprotkb:Q9NYK4|uniprotkb:Q9UL20|uniprotkb:B2REB9|uniprotkb:B2REC0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mpzl1_human(display_long)|uniprotkb:MPZL1(gene name)|psi-mi:MPZL1(display_short)|uniprotkb:PZR(gene name synonym)|uniprotkb:UNQ849/PRO1787(orf name)|uniprotkb:Protein zero-related(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000197965(gene)|ensembl:ENST00000359523(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009986"(cell surface)|interpro:IPR000920(Myelin P0 protein)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR029870|interpro:IPR036179|rcsb pdb:6IGO|rcsb pdb:6IGT|rcsb pdb:6IGW|refseq:NP_003944.1|refseq:NP_078845.3|refseq:NP_001139663.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NdvJG6RocnCX10KdIhiJ9LmwMNs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7Z434 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-995373|uniprotkb:Q3I0Y2|uniprotkb:Q5T7I6|uniprotkb:Q86VY7|uniprotkb:Q9H1H3|uniprotkb:Q9H4Y1|uniprotkb:Q9H8D3|uniprotkb:Q9ULE9|uniprotkb:Q2HWT5|ensembl:ENSP00000401980|uniprotkb:M1P2Z0|uniprotkb:A8K6X0|uniprotkb:F5H6C8|uniprotkb:B2BD33|uniprotkb:B2BD34 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mavs_human(display_long)|uniprotkb:Interferon beta promoter stimulator protein 1(gene name synonym)|uniprotkb:Virus-induced-signaling adapter(gene name synonym)|uniprotkb:CARD adapter inducing interferon beta(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 031N(gene name synonym)|uniprotkb:MAVS(gene name)|psi-mi:MAVS(display_short)|uniprotkb:IPS1(gene name synonym)|uniprotkb:KIAA1271(gene name synonym)|uniprotkb:VISA(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001193420.1|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050700"(CARD domain binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0060340"(positive regulation of type I interferon-mediated signaling pathway)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0060760"(positive regulation of response to cytokine stimulus)|ensembl:ENSG00000088888(gene)|ensembl:ENST00000428216(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002218"(activation of innate immune response)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002735"(positive regulation of myeloid dendritic cell cytokine production)|go:"GO:0005739"(mitochondrion)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0071651"("positive regulation of chemokine (C-C motif) ligand 5 production")|go:"GO:0071660"(positive regulation of IP-10 production)|go:"GO:1900063"(regulation of peroxisome organization)|interpro:IPR011029(DEATH-like)|interpro:IPR026148|interpro:IPR031964|interpro:IPR042144|mint:Q7Z434|rcsb pdb:2MS7|rcsb pdb:2MS8|rcsb pdb:2VGQ|rcsb pdb:3J6C|rcsb pdb:3J6J|rcsb pdb:3RC5|rcsb pdb:4P4H|rcsb pdb:4Z8M|rcsb pdb:5JEK|reactome:R-HSA-168928|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440|reactome:R-HSA-5689896|refseq:NP_065797.2|dip:DIP-35445N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NUZJ/I/rKEG17NeqQS067haIDhY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P52594 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-996560|uniprotkb:Q15277|uniprotkb:Q4VAS0|uniprotkb:Q4VAS1|uniprotkb:Q4VAS3|uniprotkb:Q53QT8|uniprotkb:Q53R11|uniprotkb:B3KUL1|uniprotkb:E9PHX7|ensembl:ENSP00000312059 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:agfg1_human(display_long)|uniprotkb:HIV-1 Rev-binding protein(gene name synonym)|uniprotkb:Rev-interacting protein(gene name synonym)|uniprotkb:Rev/Rex activation domain-binding protein(gene name synonym)|uniprotkb:AGFG1(gene name)|psi-mi:AGFG1(display_short)|uniprotkb:RAB(gene name synonym)|uniprotkb:RIP(gene name synonym)|uniprotkb:HRB(gene name synonym)|uniprotkb:Nucleoporin-like protein RIP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001128660.1|refseq:NP_001128661.1|refseq:NP_004495.2|ensembl:ENSP00000312059|ensembl:ENST00000373671|ensembl:ENSP00000362775|ensembl:ENST00000409171|ensembl:ENSP00000387218|ensembl:ENST00000409979|ensembl:ENSP00000387282|refseq:NP_001128659.1|go:"GO:0005643"(nuclear pore)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|rcsb pdb:2D9L|rcsb pdb:2OLM|rcsb pdb:2VX8|reactome:R-HSA-8856825|reactome:R-HSA-8856828|ensembl:ENSG00000173744(gene)|ensembl:ENST00000310078(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|dip:DIP-35546N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:dmA7pBiLW9jnoJellR8WQP1zD6g9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9C0H9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1393949|uniprotkb:Q8N4W8|uniprotkb:Q75T46|ensembl:ENSP00000480869|ensembl:ENSP00000484715 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:srcn1_human(display_long)|uniprotkb:SRCIN1(gene name)|psi-mi:SRCIN1(display_short)|uniprotkb:KIAA1684(gene name synonym)|uniprotkb:P140(gene name synonym)|uniprotkb:p130Cas-associated protein(gene name synonym)|uniprotkb:p140Cap(gene name synonym)|uniprotkb:SNAP-25-interacting protein(gene name synonym)|uniprotkb:SNIP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_079524.2|ensembl:ENSG00000273608(gene)|ensembl:ENSG00000277363(gene)|ensembl:ENST00000615049(transcript)|ensembl:ENST00000617146(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0006887"(exocytosis)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0061099"(negative regulation of protein tyrosine kinase activity)|go:"GO:0098793"(presynapse)|interpro:IPR022782|interpro:IPR026727|mint:Q9C0H9|go:"GO:0030234"(enzyme regulator activity) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6POWT5mqv6jfEOrlfFhjn1Aq5c49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9C0C2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2104458|uniprotkb:Q6PJ35|uniprotkb:Q6ZV74|uniprotkb:A7E2F8|intact:EBI-28975617|ensembl:ENSP00000350990|ensembl:ENSP00000437271 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tb182_human(display_long)|uniprotkb:TNKS1BP1(gene name)|psi-mi:TNKS1BP1(display_short)|uniprotkb:KIAA1741(gene name synonym)|uniprotkb:TAB182(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_006718788.1|ensembl:ENSP00000350990|ensembl:ENSP00000437271|refseq:NP_203754.2|ensembl:ENSG00000149115(gene)|ensembl:ENST00000358252(transcript)|ensembl:ENST00000532437(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006302"(double-strand break repair)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0010800"(positive regulation of peptidyl-threonine phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019899"(enzyme binding)|go:"GO:0030014"(CCR4-NOT complex)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0071532"(ankyrin repeat binding)|interpro:IPR032764|interpro:IPR040006|reactome:R-HSA-429947|reactome:R-HSA-6804115 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:pOIaK7wn7iYvUHbSA0kUZlIgtgw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96KN1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-9057780|ensembl:ENSP00000302578|ensembl:ENSP00000498944 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lrat2_human(display_long)|uniprotkb:LRATD2(gene name)|psi-mi:LRATD2(display_short)|uniprotkb:BCMP101(gene name synonym)|uniprotkb:Breast cancer membrane protein 101(gene name synonym)|uniprotkb:FAM84B(gene name synonym)|uniprotkb:LRAT domain-containing 2(gene name synonym)|uniprotkb:NSE2(gene name synonym)|uniprotkb:Protein FAM84B(gene name synonym)|uniprotkb:Protein NSE2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_777571.1|refseq:XP_016868596.1|ensembl:ENSG00000168672(gene)|ensembl:ENST00000304916(transcript)|ensembl:ENST00000652209(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|interpro:IPR007053(NC)|interpro:IPR028815|interpro:IPR043299|mint:Q96KN1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:09B6ewEPdwu5FjCI/CtFg3C9Rg49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13017 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7237884|ensembl:ENSP00000371897|ensembl:ENSP00000441692|uniprotkb:Q05BU8|uniprotkb:Q59ER0|uniprotkb:Q6DHZ3|uniprotkb:Q05BE8|uniprotkb:D3DS90|uniprotkb:A8KAA1|intact:MINT-1191615|uniprotkb:D3DS89|uniprotkb:A1L375|uniprotkb:A1L376 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rhg05_human(display_long)|uniprotkb:ARHGAP5(gene name)|psi-mi:ARHGAP5(display_short)|uniprotkb:RHOGAP5(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 5(gene name synonym)|uniprotkb:p190-B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000371897|ensembl:ENST00000396582|ensembl:ENSP00000379827|ensembl:ENST00000433497|ensembl:ENSP00000407395|ensembl:ENSP00000441692|ensembl:ENST00000556611|ensembl:ENSP00000452222|ensembl:ENSG00000100852(gene)|ensembl:ENST00000345122(transcript)|ensembl:ENST00000539826(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007155"(cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030879"(mammary gland development)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR001806(Ras GTPase)|interpro:IPR002713(FF)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027417|interpro:IPR032835|interpro:IPR036517|interpro:IPR039006|interpro:IPR039007|mint:Q13017|rcsb pdb:2EE4|rcsb pdb:2EE5|rcsb pdb:5U4V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001164.2|refseq:NP_001025226.1|refseq:XP_005267692.1|refseq:XP_005267693.1|refseq:XP_016876776.1|refseq:XP_016876777.1 - - function:GTPase-activating protein for Rho family members. May play a role in the reduction of the p21rasGTPase-activating potential of p120GAP|comment:mint|comment:homomint figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:CcK8+6n27QR+L45eRsmnJP82TQE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TE68 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7487998|uniprotkb:Q9GZQ2|uniprotkb:Q9NXH0|intact:MINT-4829629|uniprotkb:Q9BSQ2|uniprotkb:Q8NC10|uniprotkb:Q96BB7|uniprotkb:Q71RE2|ensembl:ENSP00000201647 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:es8l1_human(display_long)|uniprotkb:EPS8L1(gene name)|psi-mi:EPS8L1(display_short)|uniprotkb:DRC3(gene name synonym)|uniprotkb:EPS8R1(gene name synonym)|uniprotkb:PP10566(orf name)|uniprotkb:Epidermal growth factor receptor pathway substrate 8-related protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_573441.2|refseq:NP_060199.3|ensembl:ENSG00000131037(gene)|ensembl:ENST00000201647(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0042608"(T cell receptor binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q8TE68|rcsb pdb:2K2M|rcsb pdb:2ROL - - comment:mint|function:Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+6FNaPhLMckwu8jRsJiBKKWYYOI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BXI6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7815040|uniprotkb:Q20WK7|ensembl:ENSP00000215790|uniprotkb:O76053|uniprotkb:Q543A2|intact:MINT-195567|uniprotkb:B3KXT8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tb10a_human(display_long)|uniprotkb:TBC1D10A(gene name)|psi-mi:TBC1D10A(display_short)|uniprotkb:EPI64(gene name synonym)|uniprotkb:TBC1D10(gene name synonym)|uniprotkb:Rab27A-GAP-alpha(gene name synonym)|uniprotkb:EBP50-PDX interactor of 64 kDa(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000099992(gene)|ensembl:ENST00000215790(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097202"(activation of cysteine-type endopeptidase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|reactome:R-HSA-8854214|go:"GO:0045862"(positive regulation of proteolysis)|refseq:NP_114143.1|refseq:NP_001191169.1 - - comment:mint figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Do8NzkxWvdZfnkD7Zhm56oGOnWQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IYB1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11323212|uniprotkb:Q86VD8|ensembl:ENSP00000376246 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:m21d2_human(display_long)|uniprotkb:MB21D2(gene name)|psi-mi:MB21D2(display_short)|uniprotkb:C3orf59(gene name synonym)|uniprotkb:Mab-21 domain-containing protein 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_848591.2|ensembl:ENSG00000180611(gene)|ensembl:ENST00000392452(transcript)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR024810 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:v0TcSSKN+u3PM7txxIZwT+CwfEQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H201 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7221344|intact:MINT-1199053|uniprotkb:Q9BVN6|uniprotkb:A8K6J3|uniprotkb:A8KAB2|uniprotkb:Q9NWK2|intact:EBI-28967454|ensembl:ENSP00000268933 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:epn3_human(display_long)|uniprotkb:EPN3(gene name)|psi-mi:EPN3(display_short)|uniprotkb:EPS-15-interacting protein 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000268933|ensembl:ENST00000510045|ensembl:ENSP00000421933|refseq:NP_060427.2|ensembl:ENSG00000049283(gene)|ensembl:ENST00000268933(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990175"(EH domain binding)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR027318 - - comment:mint|comment:homomint figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:jUdhw8lZdwADbilLc4JcpyGeKRQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6P1N0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7112364|intact:EBI-28978458|ensembl:ENSP00000313601|ensembl:ENSP00000500461|intact:MINT-4827481|uniprotkb:Q7Z435|uniprotkb:Q86XV0|uniprotkb:Q9H603|uniprotkb:Q8NF89|uniprotkb:Q9NXI1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:c2d1a_human(display_long)|uniprotkb:CC2D1A(gene name)|psi-mi:CC2D1A(display_short)|uniprotkb:AKI1(gene name synonym)|uniprotkb:Akt kinase-interacting protein 1(gene name synonym)|uniprotkb:Five prime repressor element under dual repression-binding protein 1(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 023N(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000313601|ensembl:ENST00000589606|ensembl:ENSP00000467526|ensembl:ENSP00000500461|ensembl:ENST00000672339|ensembl:ENSP00000500343|ensembl:ENSG00000132024(gene)|ensembl:ENSG00000288293(gene)|ensembl:ENST00000318003(transcript)|ensembl:ENST00000672017(transcript)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0001650"(fibrillar center)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0016020"(membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1905381"(negative regulation of snRNA transcription by RNA polymerase II)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR006608(Protein of unknown function DM14)|interpro:IPR035892|interpro:IPR037772|interpro:IPR039725|refseq:NP_060191.3|refseq:XP_005260030.1 - - comment:mint|comment:homomint|function:"Transcription factor that binds specifically to the FRE (five repressor element) and represses HTR1A gene transcription in neuronal cells. The combination of calcium and ATP specifically inactivates the binding with FRE. May play a role in the altered regulation of HTR1A associated with anxiety and major depression. Mediates HDAC-independent repression of HTR1A promoter in neuronal cell"|function:"Defects in CC2D1A are the cause of non-syndromic mental retardation autosomal recessive type 3 (MRT3) [MIM:608443]. Patients display severe mental retardation and psychomotor development delay in early childhood. Non-syndromic mental retardation patients do not manifest other clinical signs" figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:epJzfetEvVa5rJirbt3Ox8cEkqA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q3KP66 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7545562|uniprotkb:E9PFY0|uniprotkb:Q9NVI0|uniprotkb:B4E1K9|uniprotkb:Q9NV65|intact:MINT-3976349|intact:EBI-28986069|ensembl:ENSP00000356311 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:inava_human(display_long)|uniprotkb:INAVA(gene name)|psi-mi:INAVA(display_short)|uniprotkb:C1orf106(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011508057.1|refseq:XP_011508056.1|ensembl:ENSP00000356311|ensembl:ENST00000413687|ensembl:ENSP00000392105|refseq:NP_060735.3|refseq:NP_001136041.1|ensembl:ENSG00000163362(gene)|ensembl:ENST00000367342(transcript)|go:"GO:0000187"(obsolete activation of MAPK activity)|go:"GO:0002221"(pattern recognition receptor signaling pathway)|go:"GO:0002720"(positive regulation of cytokine production involved in immune response)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0032494"(response to peptidoglycan)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0032733"(positive regulation of interleukin-10 production)|go:"GO:0045087"(innate immune response)|go:"GO:0060729"(intestinal epithelial structure maintenance)|go:"GO:0070431"(nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:1903409"(reactive oxygen species biosynthetic process)|interpro:IPR021774|interpro:IPR039106|interpro:IPR043447|mint:Q3KP66|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade) - - comment:mint figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GiOsKhWhDTcpelLSwIGbYb9Q/NE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14574 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-6163585|intact:EBI-28985956|uniprotkb:A6NN35|uniprotkb:Q14200|uniprotkb:Q9HAZ9|ensembl:ENSP00000353608 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dsc3_human(display_long)|uniprotkb:Cadherin family member 3(gene name synonym)|uniprotkb:DSC4(gene name synonym)|uniprotkb:Desmocollin-4(gene name synonym)|uniprotkb:HT-CP(gene name synonym)|uniprotkb:DSC3(gene name)|psi-mi:DSC3(display_short)|uniprotkb:CDHF3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001932.2|refseq:NP_077741.2|ensembl:ENSP00000392068|ensembl:ENST00000434452|ensembl:ENSP00000353608|ensembl:ENSG00000134762(gene)|ensembl:ENST00000360428(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|mint:Q14574|reactome:R-HSA-6805567|reactome:R-HSA-6809371|interpro:IPR002126(Cadherin) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:2En63we0WgDfQQY2f4qQHK/clSI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95171 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7543896|uniprotkb:B7Z797|intact:MINT-8162407|intact:UNK-5430852|uniprotkb:Q86X00|intact:UNK-5458327|uniprotkb:Q53H61|uniprotkb:F5H651|uniprotkb:Q5W0S8|uniprotkb:Q5W0S9|intact:MINT-3975264|ensembl:ENSP00000302579 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:scel_human(display_long)|uniprotkb:SCEL(gene name)|psi-mi:SCEL(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_659001.2|refseq:NP_001154178.1|refseq:NP_003834.3|ensembl:ENSG00000136155(gene)|ensembl:ENST00000349847(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0008544"(epidermis development)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009792"(embryo development ending in birth or egg hatching)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|mint:O95171 - - comment:mint|function:May function in the assembly or regulation of proteins in the cornified envelope. The LIM domain may be involved in homotypic or heterotypic associations and may function to localize sciellin to the cornified envelope figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:1sNj7h14CEpm44d5qulY/tWlYgE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96RY5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7128475|ensembl:ENSP00000293925|ensembl:ENSP00000380559|uniprotkb:Q9P2C1|uniprotkb:B1AJY1|uniprotkb:A8MZL1|uniprotkb:Q8NDN1|intact:MINT-1370680 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:crml_human(display_long)|uniprotkb:CRAMP1(gene name)|psi-mi:CRAMP1(display_short)|uniprotkb:C16orf34(gene name synonym)|uniprotkb:CRAMP1L(gene name synonym)|uniprotkb:Cramped chromatin regulator homolog 1(gene name synonym)|uniprotkb:HN1L(gene name synonym)|uniprotkb:Hematological and neurological expressed 1-like protein(gene name synonym)|uniprotkb:KIAA1426(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N interpro:IPR017884|ensembl:ENSG00000007545(gene)|ensembl:ENST00000293925(transcript)|ensembl:ENST00000397412(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0007389"(pattern specification process)|interpro:IPR001005(SANT, DNA-binding)|refseq:NP_065876.3 - - comment:mint|comment:homomint figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:480K9t0nkljILuwAdKb0QjaedB09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15427 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-7600166|uniprotkb:Q2M1P8|intact:MINT-4526381|uniprotkb:B3KXG8|ensembl:ENSP00000376150|ensembl:ENSP00000376152|ensembl:ENSP00000462405|ensembl:ENSP00000463978|ensembl:ENSP00000464112|ensembl:ENSP00000464625|ensembl:ENSP00000482013|ensembl:ENSP00000483212 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mot4_human(display_long)|uniprotkb:SLC16A3(gene name)|psi-mi:SLC16A3(display_short)|uniprotkb:MCT4(gene name synonym)|uniprotkb:Solute carrier family 16 member 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011521909.1|refseq:NP_001193879.1|refseq:NP_001193880.1|refseq:NP_001035888.1|refseq:NP_004198.1|refseq:NP_001035887.1|refseq:NP_001193881.1|ensembl:ENSG00000141526(gene)|ensembl:ENST00000392339(transcript)|ensembl:ENST00000392341(transcript)|ensembl:ENST00000580189(transcript)|ensembl:ENST00000581287(transcript)|ensembl:ENST00000582743(transcript)|ensembl:ENST00000584689(transcript)|ensembl:ENST00000617373(transcript)|ensembl:ENST00000619321(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0008028"(monocarboxylic acid transmembrane transporter activity)|go:"GO:0015129"(lactate transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015718"(monocarboxylic acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035879"(plasma membrane lactate transport)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR004743(Monocarboxylate transporter)|interpro:IPR011701(Major facilitator superfamily MFS-1)|interpro:IPR020846|interpro:IPR030756|interpro:IPR036259|mint:O15427|reactome:R-HSA-210991|reactome:R-HSA-433692|reactome:R-HSA-70268 - - comment:mint|function:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate|comment:homomint figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ipq+K2KMGnogWD9ouLcBjZ53ICs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5SYE7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-9640051|uniprotkb:Q5SYE8|uniprotkb:Q3ZCS5|uniprotkb:Q9P2J0|ensembl:ENSP00000394546 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nhsl1_human(display_long)|uniprotkb:NHSL1(gene name)|psi-mi:NHSL1(display_short)|uniprotkb:C6orf63(gene name synonym)|uniprotkb:KIAA1357(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000343505|ensembl:ENSP00000344672|ensembl:ENSP00000394546|refseq:NP_001137532.1|refseq:NP_065197.1|dip:DIP-47303N|ensembl:ENSG00000135540(gene)|ensembl:ENST00000427025(transcript)|go:"GO:0030154"(cell differentiation)|interpro:IPR024845|mint:Q5SYE7 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fSt25Mtm6KgIdpf9rD+jhzp4rqo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q92738 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-8684930|uniprotkb:Q15400|uniprotkb:Q7L0K9|uniprotkb:A8KA79|intact:MINT-1518588|uniprotkb:Q5VV10|ensembl:ENSP00000476462 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:us6nl_human(display_long)|uniprotkb:USP6NL(gene name)|psi-mi:USP6NL(display_short)|uniprotkb:KIAA0019(gene name synonym)|uniprotkb:Related to the N-terminus of tre(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055503.1|refseq:NP_001073960.1|ensembl:ENSG00000148429(gene)|ensembl:ENST00000609104(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0019068"(virion assembly)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0035526"(retrograde transport, plasma membrane to Golgi)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|reactome:R-HSA-6811440 - - comment:mint|function:Acts as a GTPase-activating protein for RAB5A. Involved in receptor trafficking. In complex with EPS8 inhibits internalization of EGFR figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:R6Zcg3PPIbqU3k8dozBFa3POnzE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q16625 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2903088|ensembl:ENSP00000347379|ensembl:ENSP00000379719|ensembl:ENSP00000505426|ensembl:ENSP00000505541|ensembl:ENSP00000506162|uniprotkb:B5BU70|uniprotkb:Q8N6K1|uniprotkb:D2DU64|uniprotkb:D2DU65|uniprotkb:D2IGC0|uniprotkb:D2IGC1|uniprotkb:E2CYV9|uniprotkb:Q5U1V4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ocln_human(display_long)|uniprotkb:OCLN(gene name)|psi-mi:OCLN(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001192183.1|refseq:NP_001192184.1|refseq:NP_002529.1|rcsb pdb:1WPA|rcsb pdb:1XAW|rcsb pdb:3G7C|reactome:R-HSA-351906|reactome:R-HSA-8935964|ensembl:ENSG00000197822(gene)|ensembl:ENST00000355237(transcript)|ensembl:ENST00000396442(transcript)|ensembl:ENST00000680027(transcript)|ensembl:ENST00000681041(transcript)|ensembl:ENST00000681586(transcript)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010827"(regulation of glucose transmembrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030054"(cell junction)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070160"(tight junction)|go:"GO:0070673"(response to interleukin-18)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|interpro:IPR002958(Occludin)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR036259|refseq:XP_016864403.1|refseq:XP_016864402.1|dip:DIP-42791N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RyZ9uIVH0TdDwlIFaGJJYbuHvmY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IVL1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-741200|ensembl:ENSP00000379396|uniprotkb:Q8IVK3|uniprotkb:Q8IVK4|uniprotkb:Q8IVK5|uniprotkb:Q8IVK6|uniprotkb:Q8IVK7|uniprotkb:Q8IVK8|uniprotkb:Q8NHC9|uniprotkb:Q8NHD0|uniprotkb:Q8TDE9|uniprotkb:Q8TDF0|uniprotkb:Q8TEB3|uniprotkb:Q96B30|uniprotkb:Q9NUZ6|uniprotkb:Q9NVM7|uniprotkb:Q9P2C8|uniprotkb:A6NEC1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nav2_human(display_long)|uniprotkb:Helicase APC down-regulated 1(gene name synonym)|uniprotkb:Retinoic acid inducible in neuroblastoma 1(gene name synonym)|uniprotkb:Steerin-2(gene name synonym)|uniprotkb:Pore membrane and/or filament-interacting-like protein 2(gene name synonym)|uniprotkb:Unc-53 homolog 2(gene name synonym)|uniprotkb:NAV2(gene name)|psi-mi:NAV2(display_short)|uniprotkb:HELAD1(gene name synonym)|uniprotkb:KIAA1419(gene name synonym)|uniprotkb:POMFIL2(gene name synonym)|uniprotkb:RAINB1(gene name synonym)|uniprotkb:STEERIN2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000166833(gene)|ensembl:ENST00000396087(transcript)|go:"GO:0003025"(regulation of systemic arterial blood pressure by baroreceptor feedback)|go:"GO:0005524"(ATP binding)|go:"GO:0005614"(interstitial matrix)|go:"GO:0005654"(nucleoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0007608"(sensory perception of smell)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008201"(heparin binding)|go:"GO:0021554"(optic nerve development)|go:"GO:0021563"(glossopharyngeal nerve development)|go:"GO:0021564"(vagus nerve development)|go:"GO:0022008"(neurogenesis)|go:"GO:0043138"(3'-5' DNA helicase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR027417|interpro:IPR036872|interpro:IPR039041|rcsb pdb:2YRN|refseq:NP_001104488.1|refseq:NP_660093.2|refseq:NP_892009.3|refseq:XP_011518754.1|refseq:NP_001231892.1|refseq:XP_006718431.1|refseq:NP_001104489.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:OfSGuKrpZGae4NcKYPRCXm4/CcQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q07617 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10965756|ensembl:ENSP00000251809|ensembl:ENSP00000373450|uniprotkb:B3KQ58|uniprotkb:Q7Z5G1|uniprotkb:G3XAM3|uniprotkb:A6NP70 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:spag1_human(display_long)|uniprotkb:SPAG1(gene name)|psi-mi:SPAG1(display_short)|uniprotkb:HSD-3.8(gene name synonym)|uniprotkb:Infertility-related sperm protein Spag-1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003105.2|refseq:NP_757367.1|refseq:XP_011515544.1|refseq:XP_011515545.1|ensembl:ENSG00000104450(gene)|ensembl:ENST00000251809(transcript)|ensembl:ENST00000388798(transcript)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007338"(single fertilization)|go:"GO:0016787"(hydrolase activity)|go:"GO:0070286"(axonemal dynein complex assembly)|interpro:IPR001440(Tetratricopeptide TPR-1)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR025986|rcsb pdb:6I57|rcsb pdb:7BEV - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Zv94KFu5kS80BaqOkwBtJkcGvtY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O00221 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-355098|uniprotkb:Q5T9V9|intact:EBI-28973237|ensembl:ENSP00000275015 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ikbe_human(display_long)|uniprotkb:IKBE(gene name synonym)|uniprotkb:NFKBIE(gene name)|psi-mi:NFKBIE(display_short)|uniprotkb:I-kappa-B-epsilon(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004547.2|ensembl:ENSP00000275015|ensembl:ENST00000275015(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000146232(gene)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|reactome:R-HSA-1169091|go:"GO:0005829"(cytosol)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|dip:DIP-27533N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:5TEjEGv4jKRrWPpk6jTR+LF97zA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35240 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1014472|uniprotkb:O95683|uniprotkb:Q8WUJ2|uniprotkb:Q969N0|uniprotkb:Q969Q3|uniprotkb:Q96T30|uniprotkb:Q96T31|uniprotkb:Q96T32|uniprotkb:Q96T33|uniprotkb:Q9BTW3|uniprotkb:Q9UNG9|uniprotkb:Q9UNH3|uniprotkb:Q9UNH4|ensembl:ENSP00000344666 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:merl_human(display_long)|uniprotkb:Moesin-ezrin-radixin-like protein(gene name synonym)|uniprotkb:Neurofibromin-2(gene name synonym)|uniprotkb:Schwannomin(gene name synonym)|uniprotkb:Schwannomerlin(gene name synonym)|uniprotkb:NF2(gene name)|psi-mi:NF2(display_short)|uniprotkb:SCH(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000259.1|refseq:NP_057502.2|refseq:NP_861546.1|refseq:NP_861966.1|refseq:NP_861967.1|refseq:NP_861968.1|refseq:NP_861969.1|refseq:NP_861970.1|refseq:NP_861971.1|ensembl:ENSG00000186575(gene)|ensembl:ENST00000338641(transcript)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001953"(negative regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007398"(ectoderm development)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014010"(Schwann cell proliferation)|go:"GO:0014013"(regulation of gliogenesis)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0035330"(regulation of hippo signaling)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042532"(negative regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043005"(neuron projection)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0044297"(cell body)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0046426"(negative regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070306"(lens fiber cell differentiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:1900180"(regulation of protein localization to nucleus)|go:"GO:2000177"(regulation of neural precursor cell proliferation)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35240|rcsb pdb:1H4R|rcsb pdb:3U8Z|rcsb pdb:4ZRI|rcsb pdb:4ZRJ|rcsb pdb:6CDS|reactome:R-HSA-2029482|reactome:R-HSA-5627123|dip:DIP-35389N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:YyzGKX6SmAvbiIgejNTvu/64uXc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y265 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353675|uniprotkb:P82276|uniprotkb:Q1KMR0|uniprotkb:Q53HK5|uniprotkb:Q53HL7|uniprotkb:Q53Y27|uniprotkb:Q9BSX9|uniprotkb:B2R5S0|ensembl:ENSP00000318297|ensembl:ENSP00000494621 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ruvb1_human(display_long)|uniprotkb:RUVBL1(gene name)|psi-mi:RUVBL1(display_short)|uniprotkb:NMP238(gene name synonym)|uniprotkb:TIP49(gene name synonym)|uniprotkb:TIP49A(gene name synonym)|uniprotkb:49 kDa TATA box-binding protein-interacting protein(gene name synonym)|uniprotkb:TIP49a(gene name synonym)|uniprotkb:Pontin 52(gene name synonym)|uniprotkb:Nuclear matrix protein 238(gene name synonym)|uniprotkb:54 kDa erythrocyte cytosolic protein(gene name synonym)|uniprotkb:INO80H(gene name synonym)|uniprotkb:TIP60-associated protein 54-alpha(gene name synonym)|uniprotkb:INO80 complex subunit H(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003698.1|go:"GO:0016020"(membrane)|go:"GO:0016363"(nuclear matrix)|go:"GO:0016573"(histone acetylation)|go:"GO:0017025"(TBP-class protein binding)|go:"GO:0031011"(Ino80 complex)|go:"GO:0035267"(NuA4 histone acetyltransferase complex)|go:"GO:0040008"(regulation of growth)|go:"GO:0043139"(5'-3' DNA helicase activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043967"(histone H4 acetylation)|go:"GO:0043968"(histone H2A acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051301"(cell division)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071339"(MLL1 complex)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097255"(R2TP complex)|go:"GO:0120293"(dynein axonemal particle)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR003593(AAA+ ATPase, core)|interpro:IPR010339(TIP49, C-terminal)|interpro:IPR027238|interpro:IPR027417|interpro:IPR037938|interpro:IPR041048|mint:Q9Y265|rcsb pdb:2C9O|rcsb pdb:2XSZ|rcsb pdb:5OAF|rcsb pdb:6FO1|rcsb pdb:6HTS|rcsb pdb:6IGM|rcsb pdb:6K0R|rcsb pdb:6QI8|rcsb pdb:6QI9|rcsb pdb:7AHO|reactome:R-HSA-171319|reactome:R-HSA-201722|reactome:R-HSA-3214847|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-5696394|reactome:R-HSA-606279|ensembl:ENSG00000175792(gene)|ensembl:ENSG00000284901(gene)|ensembl:ENST00000322623(transcript)|ensembl:ENST00000643444(transcript)|go:"GO:0000492"(box C/D snoRNP assembly)|go:"GO:0000812"(Swr1 complex)|go:"GO:0001094"(TFIID-class transcription factor complex binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006310"(DNA recombination)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007049"(cell cycle)|go:"GO:0007283"(spermatogenesis)|refseq:NP_001306013.1|dip:DIP-29937N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+FA/xQTUldQoWGRgad9U8vZpTHw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P09525 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2556852|uniprotkb:B4DDF9|uniprotkb:Q9BWK1|uniprotkb:Q96F33|ensembl:ENSP00000377833 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:anxa4_human(display_long)|uniprotkb:ANX4(gene name synonym)|uniprotkb:Annexin-4(gene name synonym)|uniprotkb:Annexin IV(gene name synonym)|uniprotkb:Lipocortin IV(gene name synonym)|uniprotkb:Endonexin I(gene name synonym)|uniprotkb:Chromobindin-4(gene name synonym)|uniprotkb:Protein II(gene name synonym)|uniprotkb:P32.5(gene name synonym)|uniprotkb:Placental anticoagulant protein II(gene name synonym)|uniprotkb:PP4-X(gene name synonym)|uniprotkb:35-beta calcimedin(gene name synonym)|uniprotkb:Carbohydrate-binding protein p33/p41(gene name synonym)|uniprotkb:ANXA4(gene name)|psi-mi:ANXA4(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001144.1|ensembl:ENSG00000196975(gene)|ensembl:ENST00000394295(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0007165"(signal transduction)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0012506"(vesicle membrane)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0004859"(phospholipase inhibitor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001464(Annexin)|interpro:IPR002391(Annexin, type IV)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|rcsb pdb:2ZOC|refseq:NP_001307627.1|refseq:NP_001307629.1|refseq:NP_001307631.1|refseq:XP_016859432.1|refseq:XP_016859433.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9FM1bXFxch8Srj1njfDiNXtowDU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H0B6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-726994|ensembl:ENSP00000314837|ensembl:ENSP00000377631|ensembl:ENSP00000399403|uniprotkb:Q9H9C8|uniprotkb:Q9HA20|uniprotkb:B2RDY4|uniprotkb:A8MXL7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:klc2_human(display_long)|uniprotkb:KLC2(gene name)|psi-mi:KLC2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000174996(gene)|ensembl:ENST00000316924(transcript)|ensembl:ENST00000394067(transcript)|ensembl:ENST00000417856(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0016938"(kinesin I complex)|go:"GO:0016020"(membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0032418"(lysosome localization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|interpro:IPR002151(Kinesin light chain)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR015792(Kinesin light chain repeat)|interpro:IPR019734|mint:Q9H0B6|rcsb pdb:3CEQ|rcsb pdb:3EDT|reactome:R-HSA-2132295|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|refseq:NP_001128246.1|refseq:NP_001128247.1|refseq:NP_001128248.1|refseq:NP_073733.1|refseq:NP_001305663.1|refseq:XP_005274240.1|dip:DIP-40381N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:VjzT5tI182sjUbhjxC1bK9GSMHo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y5X3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-715760|uniprotkb:Q52LC4|uniprotkb:B7ZKN3|uniprotkb:Q9BWP0|uniprotkb:Q7KZN0|uniprotkb:D3DW26|ensembl:ENSP00000366988|ensembl:ENSP00000366998 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snx5_human(display_long)|uniprotkb:SNX5(gene name)|psi-mi:SNX5(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055241.1|refseq:NP_689413.1|ensembl:ENSG00000089006(gene)|ensembl:ENST00000377759(transcript)|ensembl:ENST00000377768(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001891"(phagocytic cup)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006907"(pinocytosis)|go:"GO:0007174"(epidermal growth factor catabolic process)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0034452"(dynactin binding)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0035815"(positive regulation of renal sodium excretion)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045776"(negative regulation of blood pressure)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070685"(macropinocytic cup)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097422"(tubular endosome)|interpro:IPR001683(Phox-like)|interpro:IPR014637(Sorting nexin, Snx5/Snx6 types)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028654|interpro:IPR036871|interpro:IPR042135|mint:Q9Y5X3|rcsb pdb:1SYS|rcsb pdb:5TGH|rcsb pdb:5TGI|rcsb pdb:5TGJ|rcsb pdb:5WY2|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6N5Z|reactome:R-HSA-432722 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:VR2oUxQ4M2bm5zKeHQlao046QL09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WVQ1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-16770554|ensembl:ENSP00000307674|ensembl:ENSP00000376241|ensembl:ENSP00000467437|ensembl:ENSP00000477798|uniprotkb:B4DJ54|uniprotkb:Q7Z2J7|uniprotkb:Q8NG05|uniprotkb:Q8NHP0|uniprotkb:Q9BSD5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cant1_human(display_long)|uniprotkb:CANT1(gene name)|psi-mi:CANT1(display_short)|uniprotkb:SHAPY(gene name synonym)|uniprotkb:Apyrase homolog(gene name synonym)|uniprotkb:Putative MAPK-activating protein PM09(gene name synonym)|uniprotkb:Putative NF-kappa-B-activating protein 107(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000171302(gene)|ensembl:ENST00000302345(transcript)|ensembl:ENST00000392446(transcript)|ensembl:ENST00000591773(transcript)|ensembl:ENST00000620915(transcript)|go:"GO:0004382"(guanosine-diphosphatase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043262"(adenosine-diphosphatase activity)|go:"GO:0045134"(uridine-diphosphatase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR009283(Apyrase)|interpro:IPR036258|rcsb pdb:1S18|rcsb pdb:1S1D|rcsb pdb:2H2N|rcsb pdb:2H2U|reactome:R-HSA-6798695|refseq:NP_001153244.1|refseq:NP_001153245.1|refseq:NP_620148.1|refseq:XP_005257078.1|refseq:XP_005257079.1|refseq:XP_006721746.1|refseq:XP_011522593.1|refseq:XP_011522595.1|refseq:XP_011522596.1|refseq:XP_011522597.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:tGtx387V/C3OhZiGFjJIem4yvyM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7L1Q6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1046727|ensembl:ENSP00000386474|intact:EBI-1051097|uniprotkb:Q14281|uniprotkb:Q15394|uniprotkb:Q9BUY0|uniprotkb:B4DLZ8|uniprotkb:B4DWF7|intact:EBI-21351780 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:bzw1_human(display_long)|uniprotkb:BZW1(gene name)|psi-mi:BZW1(display_short)|uniprotkb:BZAP45(gene name synonym)|uniprotkb:KIAA0005(gene name synonym)|uniprotkb:Protein Orf(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001193996.1|refseq:NP_055485.2|ensembl:ENSG00000082153(gene)|ensembl:ENST00000409600(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|mint:Q7L1Q6|refseq:NP_001193997.1|refseq:NP_001193998.1|refseq:NP_001308617.1|refseq:NP_001308619.1|refseq:NP_001308620.1|refseq:NP_001308622.1|refseq:NP_001308623.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:4dzFp6AN4tymPA5rHNYlHCCmSaY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WZ42 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-681210|intact:EBI-1384264|intact:EBI-1058389|intact:EBI-28975411|intact:EBI-2562129|ensembl:ENSP00000465570|intact:EBI-3448943|uniprotkb:Q4ZG20|uniprotkb:Q10465|uniprotkb:Q10466|uniprotkb:Q15598|uniprotkb:Q2XUS3|uniprotkb:Q32Q60|uniprotkb:Q4U1Z6|uniprotkb:Q6NSG0|uniprotkb:Q6PDB1|uniprotkb:Q6PJP0|uniprotkb:Q7KYM2|uniprotkb:Q7KYN4|uniprotkb:Q7KYN5|uniprotkb:Q7LDM3|uniprotkb:Q7Z2X3|uniprotkb:Q8TCG8|uniprotkb:Q8WZ51|uniprotkb:Q8WZ52|uniprotkb:Q8WZ53|uniprotkb:Q8WZB3|uniprotkb:Q92761|uniprotkb:Q92762|uniprotkb:Q9UD97|uniprotkb:Q9UP84|uniprotkb:Q9Y6L9|uniprotkb:A6NKB1|uniprotkb:E7EQE6|uniprotkb:E7ET18|uniprotkb:K7ENY1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:titin_human(display_long)|uniprotkb:TTN(gene name)|psi-mi:TTN(display_short)|uniprotkb:Connectin(gene name synonym)|uniprotkb:Rhabdomyosarcoma antigen MU-RMS-40.14(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001243779.1|refseq:NP_596869.4|refseq:NP_597676.3|refseq:NP_003310.4|ensembl:ENSG00000155657(gene)|ensembl:ENST00000591111(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0002020"(protease binding)|go:"GO:0003300"(cardiac muscle hypertrophy)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0006936"(muscle contraction)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007076"(mitotic chromosome condensation)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030240"(skeletal muscle thin filament assembly)|go:"GO:0030241"(skeletal muscle myosin thick filament assembly)|go:"GO:0031430"(M band)|go:"GO:0031433"(telethonin binding)|go:"GO:0031674"(I band)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0042802"(identical protein binding)|go:"GO:0042805"(actinin binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0048769"(sarcomerogenesis)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051592"(response to calcium ion)|go:"GO:0055003"(cardiac myofibril assembly)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0060048"(cardiac muscle contraction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|ensembl:ENST00000342992|ensembl:ENSP00000343764|ensembl:ENST00000359218|ensembl:ENSP00000352154|ensembl:ENST00000360870|ensembl:ENSP00000354117|ensembl:ENST00000460472|ensembl:ENSP00000434586|ensembl:ENSP00000465570|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR004168(PPAK motif)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013098(Immunoglobulin I-set)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015129(Titin Z)|interpro:IPR036116|interpro:IPR036179|interpro:IPR040849|mint:Q8WZ42|rcsb pdb:1BPV|rcsb pdb:1G1C|rcsb pdb:1NCT|rcsb pdb:1NCU|rcsb pdb:1TIT|rcsb pdb:1TIU|rcsb pdb:1TKI|rcsb pdb:1TNM|rcsb pdb:1TNN|rcsb pdb:1WAA|rcsb pdb:1YA5|rcsb pdb:2BK8|rcsb pdb:2F8V|rcsb pdb:2ILL|rcsb pdb:2J8H|rcsb pdb:2A38|rcsb pdb:2J8O|rcsb pdb:2NZI|rcsb pdb:2RQ8|rcsb pdb:2WP3|rcsb pdb:2WWK|rcsb pdb:2WWM|rcsb pdb:2Y9R|rcsb pdb:3B43|rcsb pdb:3KNB|rcsb pdb:3LCY|rcsb pdb:3LPW|rcsb pdb:3PUC|rcsb pdb:3Q5O|rcsb pdb:3QP3|rcsb pdb:4C4K|rcsb pdb:4JNW|rcsb pdb:4O00|rcsb pdb:4UOW|rcsb pdb:5BS0|rcsb pdb:5JDD|rcsb pdb:5JDE|rcsb pdb:5JDJ|rcsb pdb:5JOE|rcsb pdb:6DL4|rcsb pdb:6H4L|rcsb pdb:4QEG|rcsb pdb:6HCI|rcsb pdb:6I0Y|rcsb pdb:6SDB|rcsb pdb:6YGN|rcsb pdb:7AHS|rcsb pdb:7NIP|reactome:R-HSA-114608|reactome:R-HSA-390522|refseq:NP_596870.2|dip:DIP-33449N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:wnuQ0Js5X0a3F1wHb7EBSHLhgvo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P61026 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-726075|uniprotkb:O88386|uniprotkb:Q6IA52|uniprotkb:Q9D7X6|uniprotkb:Q9H0T3|uniprotkb:D6W538|ensembl:ENSP00000264710 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rab10_human(display_long)|uniprotkb:RAB10(gene name)|psi-mi:RAB10(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_057215.3|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0007409"(axonogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009306"(protein secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0019003"(GDP binding)|go:"GO:0019882"(antigen processing and presentation)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0031489"(myosin V binding)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045200"(establishment of neuroblast polarity)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055037"(recycling endosome)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090150"(establishment of protein localization to membrane)|go:"GO:0097051"(establishment of protein localization to endoplasmic reticulum membrane)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1903361"(protein localization to basolateral plasma membrane)|interpro:IPR001806(Ras GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|rcsb pdb:5LPN|rcsb pdb:5SZJ|reactome:R-HSA-1445148|reactome:R-HSA-6798695|reactome:R-HSA-8873719|reactome:R-HSA-8876198|ensembl:ENSG00000084733(gene)|ensembl:ENST00000264710(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003925"(G protein activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZbfLtWtXl3z6/MYyhiZp6P1Y5tE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q86UP2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-359761|uniprotkb:Q13999|uniprotkb:Q14707|uniprotkb:Q15387|uniprotkb:Q86W57|ensembl:ENSP00000378725|ensembl:ENSP00000432149|uniprotkb:Q17RZ5|uniprotkb:B4DZ88|uniprotkb:Q5GGW3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ktn1_human(display_long)|uniprotkb:KTN1(gene name)|psi-mi:KTN1(display_short)|uniprotkb:CG1(gene name synonym)|uniprotkb:KIAA0004(gene name synonym)|uniprotkb:Kinesin receptor(gene name synonym)|uniprotkb:CG-1 antigen(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001072989.1|refseq:NP_004977.2|ensembl:ENSG00000126777(gene)|ensembl:ENST00000395314(transcript)|ensembl:ENST00000459737(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019894"(kinesin binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0045296"(cadherin binding)|interpro:IPR007794(Ribosome receptor lysine or proline rich)|interpro:IPR024854|mint:Q86UP2|refseq:XP_011535053.1|refseq:XP_011535055.1|reactome:R-HSA-381426|reactome:R-HSA-5625970|reactome:R-HSA-8957275|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9696264|reactome:R-HSA-9696270|refseq:NP_001072990.1|refseq:NP_001257943.1|refseq:XP_006720201.1|refseq:XP_006720202.1|refseq:XP_016876767.1|refseq:XP_016876771.1|refseq:XP_016876772.1|dip:DIP-27585N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:paZIiw7G2n1qUQ91xj5zi8x1Oxc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96PY5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3438448|uniprotkb:Q8N3E0|uniprotkb:Q4ZG52|uniprotkb:Q14CC9|uniprotkb:B2RZH5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:fmnl2_human(display_long)|uniprotkb:FMNL2(gene name)|psi-mi:FMNL2(display_short)|uniprotkb:FHOD2(gene name synonym)|uniprotkb:KIAA1902(gene name synonym)|uniprotkb:Formin homology 2 domain-containing protein 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N interpro:IPR043592|refseq:NP_443137.2|interpro:IPR016024(Armadillo-type fold)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR014768(GTPase-binding/formin homology 3)|mint:Q96PY5|interpro:IPR027656|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|rcsb pdb:4YC7|reactome:R-HSA-5663220|reactome:R-HSA-9013106|reactome:R-HSA-9013148|interpro:IPR042201|interpro:IPR011989(Armadillo-like helical) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:My1jgXVf11giGBKinod/inR4HH49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14789 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-709973|uniprotkb:Q14398|uniprotkb:D3DN92|uniprotkb:F1T0J2|uniprotkb:B2ZZ91|uniprotkb:E7EP74|ensembl:ENSP00000341848 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gogb1_human(display_long)|uniprotkb:Giantin(gene name synonym)|uniprotkb:Macrogolgin(gene name synonym)|uniprotkb:372 kDa Golgi complex-associated protein(gene name synonym)|uniprotkb:GOLGB1(gene name)|psi-mi:GOLGB1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004478.3|refseq:XP_011511001.1|refseq:NP_001243416.1|refseq:NP_001243417.1|refseq:XP_005247428.1|refseq:NP_001243415.1|dip:DIP-34649N|ensembl:ENSG00000173230(gene)|ensembl:ENST00000340645(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0003723"(RNA binding)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035988"(chondrocyte proliferation)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:1905793"(protein localization to pericentriolar material)|interpro:IPR003106(Leucine zipper, homeobox-associated)|interpro:IPR026202|mint:Q14789|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-9703465 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:suoNOGzPA2FjQsHQs4cdSpqYn/M9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7Z478 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-719925|uniprotkb:O75549|uniprotkb:Q63HN0|uniprotkb:Q63HN3|uniprotkb:Q8IWW2|uniprotkb:Q8N3A1|uniprotkb:Q9UMH2|intact:EBI-28967230|ensembl:ENSP00000251636 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dhx29_human(display_long)|uniprotkb:DEAH box protein 29(gene name synonym)|uniprotkb:Nucleic acid helicase DDXx(gene name synonym)|uniprotkb:DHX29(gene name)|psi-mi:DHX29(display_short)|uniprotkb:DDX29(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000251636|refseq:NP_061903.2|ensembl:ENSG00000067248(gene)|ensembl:ENST00000251636(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0008494"(translation activator activity)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0017111"(nucleoside-triphosphatase activity)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|interpro:IPR034730|refseq:NP_001332893.1|refseq:NP_001332894.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:T78lwkAmdyEefThCR1zDrVbTBYE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P51610 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-396176|intact:EBI-2832627|uniprotkb:Q6P4G5|intact:EBI-12037257|intact:EBI-14324845|ensembl:ENSP00000309555|intact:EBI-12980473 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:hcfc1_human(display_long)|uniprotkb:HCFC1(gene name)|psi-mi:HCFC1(display_short)|uniprotkb:HCF1(gene name synonym)|uniprotkb:C1 factor(gene name synonym)|uniprotkb:VP16 accessory protein(gene name synonym)|uniprotkb:VCAF(gene name synonym)|uniprotkb:CFF(gene name synonym)|uniprotkb:HFC1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005325.2|refseq:XP_006724879.1|rcsb pdb:6MA1|rcsb pdb:6MA2|rcsb pdb:6MA3|rcsb pdb:6MA4|rcsb pdb:6MA5|reactome:R-HSA-2151201|reactome:R-HSA-3214847|reactome:R-HSA-5689603|ensembl:ENSG00000172534(gene)|ensembl:ENST00000310441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000123"(histone acetyltransferase complex)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007049"(cell cycle)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0019046"(release from viral latency)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043981"(histone H4-K5 acetylation)|go:"GO:0043982"(histone H4-K8 acetylation)|go:"GO:0043984"(histone H4-K16 acetylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045787"(positive regulation of cell cycle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048188"(Set1C/COMPASS complex)|go:"GO:0050821"(protein stabilization)|go:"GO:0071339"(MLL1 complex)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR036116|interpro:IPR037854|interpro:IPR043536|mint:P51610|rcsb pdb:4GO6|rcsb pdb:4N39|rcsb pdb:4N3A|rcsb pdb:4N3B|rcsb pdb:4N3C|rcsb pdb:5LWV|dip:DIP-32955N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RzsCRe9l6md3DI87H4ZgdR9oBMI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H7U1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-714702|uniprotkb:B7WPE8|uniprotkb:Q9ULU1|uniprotkb:Q9H2S0|intact:EBI-2558596|intact:EBI-1104827|uniprotkb:B4DQU9|uniprotkb:D3DWE2|uniprotkb:B4DFY4|uniprotkb:Q8N6E9|ensembl:ENSP00000224756 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ccse2_human(display_long)|uniprotkb:CCSER2(gene name)|psi-mi:CCSER2(display_short)|uniprotkb:Coiled-coil serine-rich protein 2(gene name synonym)|uniprotkb:FAM190B(gene name synonym)|uniprotkb:KIAA1128(gene name synonym)|uniprotkb:Protein GCAP14 homolog(gene name synonym)|uniprotkb:NPD012(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001271169.1|refseq:NP_001271170.1|refseq:NP_001271171.1|refseq:NP_001271172.1|refseq:NP_061872.2|ensembl:ENSG00000107771(gene)|ensembl:ENST00000224756(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|interpro:IPR029627|interpro:IPR029629|refseq:XP_016871829.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6kwn1v/e/MUOBgzpZVvbhxfCNZs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15643 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1047183|uniprotkb:O14689|uniprotkb:O15154|uniprotkb:O95949|uniprotkb:B2RUT2|uniprotkb:Q6MZL5|ensembl:ENSP00000267622 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tripb_human(display_long)|uniprotkb:Golgi-associated microtubule-binding protein 210(gene name synonym)|uniprotkb:Clonal evolution-related gene on chromosome 14 protein(gene name synonym)|uniprotkb:Trip230(gene name synonym)|uniprotkb:TRIP11(gene name)|psi-mi:TRIP11(display_short)|uniprotkb:CEV14(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004230.2|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005856"(cytoskeleton)|go:"GO:0006366"(transcription by RNA polymerase II)|go:"GO:0006486"(protein glycosylation)|ensembl:ENSG00000100815(gene)|ensembl:ENST00000267622(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002079"(inner acrosomal membrane)|go:"GO:0002081"(outer acrosomal membrane)|go:"GO:0003281"(ventricular septum development)|go:"GO:0003413"(chondrocyte differentiation involved in endochondral bone morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007030"(Golgi organization)|go:"GO:0016607"(nuclear speck)|go:"GO:0030133"(transport vesicle)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0051216"(cartilage development)|go:"GO:0060122"(inner ear receptor cell stereocilium organization)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0099041"(vesicle tethering to Golgi)|interpro:IPR000237(GRIP)|mint:Q15643|reactome:R-HSA-5620924|reactome:R-HSA-6811438|reactome:R-HSA-9703465|ensembl:ENSP00000267622|dip:DIP-40357N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:M/XOdT1ZPDaQqMuBXsAB5p6N9LY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96JQ2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-5658691|uniprotkb:Q9H713|uniprotkb:Q9UFP4|uniprotkb:Q9HA57|uniprotkb:Q9ULN2|uniprotkb:Q9HA23|uniprotkb:B2RAR7|intact:EBI-28974156|ensembl:ENSP00000298912 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:clmn_human(display_long)|uniprotkb:Calponin-like transmembrane domain protein(gene name synonym)|uniprotkb:KIAA1188(gene name synonym)|uniprotkb:CLMN(gene name)|psi-mi:CLMN(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000298912|refseq:NP_079010.2|ensembl:ENSG00000165959(gene)|ensembl:ENST00000298912(transcript)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0007097"(nuclear migration)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0034993"(meiotic nuclear membrane microtubule tethering complex)|go:"GO:0051015"(actin filament binding)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR036872 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:5680uLyZVmMQ3D5tHa3nBD2b+Hg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P40818 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1050865|uniprotkb:Q2TB31|uniprotkb:Q7Z3U2|uniprotkb:Q86VA0|uniprotkb:Q8IWI7|ensembl:ENSP00000302239|ensembl:ENSP00000379721|uniprotkb:B4DKA8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ubp8_human(display_long)|uniprotkb:Ubiquitin-specific-processing protease 8(gene name synonym)|uniprotkb:Deubiquitinating enzyme 8(gene name synonym)|uniprotkb:USP8(gene name)|psi-mi:USP8(display_short)|uniprotkb:KIAA0055(gene name synonym)|uniprotkb:UBPY(gene name synonym)|uniprotkb:Ubiquitin isopeptidase Y(gene name synonym)|uniprotkb:Ubiquitin thioesterase 8(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001122082.1|refseq:NP_005145.3|refseq:NP_001269978.1|refseq:XP_011520495.1|ensembl:ENSG00000138592(gene)|ensembl:ENST00000307179(transcript)|ensembl:ENST00000396444(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007032"(endosome organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030496"(midbody)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043197"(dendritic spine)|go:"GO:0045296"(cadherin binding)|go:"GO:0070536"(protein K63-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR001763(Rhodanese-like)|interpro:IPR015063(Region of unknown function DUF1873)|interpro:IPR018200|interpro:IPR028889|interpro:IPR036873|interpro:IPR038765|mint:P40818|rcsb pdb:1WHB|rcsb pdb:2A9U|rcsb pdb:2GFO|rcsb pdb:2GWF|rcsb pdb:3N3K|rcsb pdb:6F09|reactome:R-HSA-1358803|reactome:R-HSA-4641263|reactome:R-HSA-5689880|reactome:R-HSA-6807004|refseq:XP_006720824.1|dip:DIP-40365N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:hpBBzyA4lc9is80ZFJBr1fyEyOM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NZN5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-821440|uniprotkb:O15086|uniprotkb:Q6P526|ensembl:ENSP00000380942 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:arhgc_human(display_long)|uniprotkb:Leukemia-associated RhoGEF(gene name synonym)|uniprotkb:ARHGEF12(gene name)|psi-mi:ARHGEF12(display_short)|uniprotkb:KIAA0382(gene name synonym)|uniprotkb:LARG(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001185594.1|refseq:NP_056128.1|refseq:NP_001288013.1|refseq:XP_011541022.1|refseq:XP_016872910.1|ensembl:ENST00000356641|ensembl:ENSP00000349056|ensembl:ENSP00000380942|dip:DIP-37887N|ensembl:ENSG00000196914(gene)|ensembl:ENST00000397843(transcript)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001331(Guanine-nucleotide dissociation stimulator, CDC24, conserved site)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR015212(Regulator of G protein signalling-like fold)|interpro:IPR035899|interpro:IPR036034|interpro:IPR036305|interpro:IPR037801|interpro:IPR037884|interpro:IPR041020|rcsb pdb:1TXD|rcsb pdb:1X86|rcsb pdb:2OMJ|rcsb pdb:2OS6|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-416572|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lAnj6rTvOnWPt6fcTzMm8G1klKY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6WCQ1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1022605|uniprotkb:Q3KQZ5|uniprotkb:Q5FB94|uniprotkb:Q6DHW2|uniprotkb:Q7Z5Y2|uniprotkb:Q8N390|uniprotkb:Q96G40|ensembl:ENSP00000342379 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mprip_human(display_long)|uniprotkb:MRIP(gene name synonym)|uniprotkb:Rho-interacting protein 3(gene name synonym)|uniprotkb:p116Rip(gene name synonym)|uniprotkb:MPRIP(gene name)|psi-mi:MPRIP(display_short)|uniprotkb:KIAA0864(gene name synonym)|uniprotkb:RHOIP3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000133030(gene)|ensembl:ENST00000341712(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR039597|mint:Q6WCQ1|reactome:R-HSA-6802952|refseq:NP_055949.2|refseq:NP_958431.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:QoGbbg2ehuQogDM1Dlxzw6xj59s9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15357 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1384248|uniprotkb:Q13577|uniprotkb:Q13578|uniprotkb:B2RTX5|ensembl:ENSP00000298229 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ship2_human(display_long)|uniprotkb:INPPL1(gene name)|psi-mi:INPPL1(display_short)|uniprotkb:SHIP2(gene name synonym)|uniprotkb:Inositol polyphosphate phosphatase-like protein 1(gene name synonym)|uniprotkb:Protein 51C(gene name synonym)|uniprotkb:SH2 domain-containing inositol 5'-phosphatase 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000298229|ensembl:ENST00000538751|ensembl:ENSP00000444619|refseq:NP_001558.3|refseq:XP_011543301.1|dip:DIP-39733N|ensembl:ENSG00000165458(gene)|ensembl:ENST00000298229(transcript)|go:"GO:0001958"(endochondral ossification)|go:"GO:0002376"(immune system process)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006006"(glucose metabolic process)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0032868"(response to insulin)|go:"GO:0034485"(phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0097178"(ruffle assembly)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000980(SH2 motif)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036691|interpro:IPR036860|mint:O15357|rcsb pdb:2K4P|rcsb pdb:2KSO|rcsb pdb:2MK2|rcsb pdb:3NR8|rcsb pdb:4A9C|rcsb pdb:5OKM|rcsb pdb:5OKN|rcsb pdb:5OKO|rcsb pdb:5OKP|rcsb pdb:6SQU|rcsb pdb:6SRR|reactome:R-HSA-1660499|reactome:R-HSA-1855204|reactome:R-HSA-912526 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:FmRJZVZS8n00OVhTEfEo5gxIvG49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P33981 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1645856|uniprotkb:Q15272|uniprotkb:Q5TCS0|uniprotkb:Q9BW51|uniprotkb:Q9NTM0|uniprotkb:E1P543|uniprotkb:B2RDW2|uniprotkb:A8K8U5|ensembl:ENSP00000358813 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ttk_human(display_long)|uniprotkb:TTK(gene name)|psi-mi:TTK(display_short)|uniprotkb:MPS1L1(gene name synonym)|uniprotkb:Phosphotyrosine picked threonine-protein kinase(gene name synonym)|uniprotkb:MPS1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003309.2|refseq:XP_011534401.1|refseq:XP_011534402.1|refseq:NP_001160163.1|dip:DIP-40642N|ensembl:ENSG00000112742(gene)|ensembl:ENST00000369798(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004712"(protein serine/threonine/tyrosine kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007059"(chromosome segregation)|go:"GO:0007094"(mitotic spindle assembly checkpoint signaling)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0016321"(female meiosis chromosome segregation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0033316"(meiotic spindle assembly checkpoint signaling)|go:"GO:0034501"(protein localization to kinetochore)|go:"GO:0042802"(identical protein binding)|go:"GO:0043515"(kinetochore binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051304"(chromosome separation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1903096"(protein localization to meiotic spindle midzone)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR027084|rcsb pdb:2X9E|rcsb pdb:2ZMC|rcsb pdb:2ZMD|rcsb pdb:3CEK|rcsb pdb:3DBQ|rcsb pdb:3GFW|rcsb pdb:3H9F|rcsb pdb:3HMN|rcsb pdb:3HMO|rcsb pdb:3HMP|rcsb pdb:3VQU|rcsb pdb:3W1F|rcsb pdb:3WYX|rcsb pdb:3WYY|rcsb pdb:3WZK|rcsb pdb:4B94|rcsb pdb:4BHZ|rcsb pdb:4BI0|rcsb pdb:4BI1|rcsb pdb:4BI2|rcsb pdb:4C4E|rcsb pdb:4C4F|rcsb pdb:4C4G|rcsb pdb:4C4H|rcsb pdb:4C4I|rcsb pdb:4C4J|rcsb pdb:4CV8|rcsb pdb:4CV9|rcsb pdb:4CVA|rcsb pdb:4D2S|rcsb pdb:4H7X|rcsb pdb:4H7Y|rcsb pdb:4JS8|rcsb pdb:4JT3|rcsb pdb:4O6L|rcsb pdb:4ZEG|rcsb pdb:5AP0|rcsb pdb:5AP1|rcsb pdb:5AP2|rcsb pdb:5AP3|rcsb pdb:5AP4|rcsb pdb:5AP5|rcsb pdb:5AP6|rcsb pdb:5AP7|rcsb pdb:5EH0|rcsb pdb:5EHL|rcsb pdb:5EHO|rcsb pdb:5EHY|rcsb pdb:5EI2|rcsb pdb:5EI6|rcsb pdb:5EI8|rcsb pdb:5LJJ|rcsb pdb:5MRB|rcsb pdb:5N7V|rcsb pdb:5N84|rcsb pdb:5N87|rcsb pdb:5N93|rcsb pdb:5N9S|rcsb pdb:5NA0|rcsb pdb:5NAD|rcsb pdb:5NTT|rcsb pdb:5O91|rcsb pdb:6B4W|rcsb pdb:6GVJ|rcsb pdb:6H3K|rcsb pdb:6N6O|rcsb pdb:6TN9|rcsb pdb:6TNB|rcsb pdb:6TNC|rcsb pdb:6TND|rcsb pdb:7CHM|rcsb pdb:7CHN|rcsb pdb:7CHT|rcsb pdb:7CIL|rcsb pdb:7CJA|rcsb pdb:7CLH|rcsb pdb:3WZJ - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Bun+wKtw2D6kl9OWIZK8l5i4n4g9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H3U1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1048763|uniprotkb:Q7L3Y6|uniprotkb:Q9H3U8|uniprotkb:Q9NSE8|uniprotkb:Q9NSE9|uniprotkb:A8K6F7|ensembl:ENSP00000407487 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:un45a_human(display_long)|uniprotkb:GCUNC-45(gene name synonym)|uniprotkb:Smooth muscle cell-associated protein 1(gene name synonym)|uniprotkb:UNC45A(gene name)|psi-mi:UNC45A(display_short)|uniprotkb:SMAP1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001034764.1|refseq:NP_061141.2|refseq:XP_011520081.1|ensembl:ENSG00000140553(gene)|ensembl:ENST00000418476(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007517"(muscle organ development)|go:"GO:0016607"(nuclear speck)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061077"(chaperone-mediated protein folding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR019734|interpro:IPR024660|rcsb pdb:2DBA|refseq:NP_001310548.1|refseq:NP_001310550.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:P/N+VqGUtK2vWzHyKq6UzC4xxdo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9P273 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2690164|uniprotkb:Q96SY2|uniprotkb:Q9NZJ2|uniprotkb:Q9NVW1|uniprotkb:Q9NV77|uniprotkb:Q5XUL9|ensembl:ENSP00000424226 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ten3_human(display_long)|uniprotkb:TENM3(gene name)|psi-mi:TENM3(display_short)|uniprotkb:KIAA1455(gene name synonym)|uniprotkb:ODZ3(gene name synonym)|uniprotkb:Protein Odd Oz/ten-m homolog 3(gene name synonym)|uniprotkb:TNM3(gene name synonym)|uniprotkb:Tenascin-M3(gene name synonym)|uniprotkb:Teneurin transmembrane protein 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001073946.1|ensembl:ENSG00000218336(gene)|ensembl:ENST00000511685(transcript)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007165"(signal transduction)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0030424"(axon)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048593"(camera-type eye morphogenesis)|go:"GO:0048666"(neuron development)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:1903385"(regulation of homophilic cell adhesion)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR006530(YD repeat)|interpro:IPR008969(Carboxypeptidase-like, regulatory region)|interpro:IPR009471(Teneurin intracellular, N-terminal)|interpro:IPR011042(Six-bladed beta-propeller, TolB-like)|interpro:IPR022385|interpro:IPR027691|interpro:IPR028916|interpro:IPR036322|refseq:XP_016863882.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:T4Ex0H/OmcOImLwf8xZD205okUo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UM47 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1236377|uniprotkb:Q9UEB3|uniprotkb:Q9UPL3|uniprotkb:Q9Y6L8|ensembl:ENSP00000263388 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:notc3_human(display_long)|uniprotkb:NOTCH3(gene name)|psi-mi:NOTCH3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000426.2|ensembl:ENSP00000263388|dip:DIP-39827N|ensembl:ENSG00000074181(gene)|ensembl:ENST00000263388(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0009986"(cell surface)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0050793"(regulation of developmental process)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022331|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q9UM47|rcsb pdb:4ZLP|rcsb pdb:5CZV|rcsb pdb:5CZX|rcsb pdb:6WQU|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013507|reactome:R-HSA-9013508|reactome:R-HSA-9017802 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:hOarWT2DBhNVF6AhV/z+NqLCEv49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UPN3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-522925|uniprotkb:E9PJT0|uniprotkb:O75053|uniprotkb:Q5VW20|uniprotkb:Q8WXY2|uniprotkb:Q9H540|uniprotkb:Q9UKP0|uniprotkb:Q9ULG9|intact:EBI-28967632|uniprotkb:B1ALC5|uniprotkb:Q8WXY1|uniprotkb:Q96PK2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:macf1_human(display_long)|uniprotkb:Actin cross-linking family protein 7(gene name synonym)|uniprotkb:Macrophin-1(gene name synonym)|uniprotkb:Trabeculin-alpha(gene name synonym)|uniprotkb:620 kDa actin-binding protein(gene name synonym)|uniprotkb:MACF1(gene name)|psi-mi:MACF1(display_short)|uniprotkb:ABP620(gene name synonym)|uniprotkb:ACF7(gene name synonym)|uniprotkb:KIAA0465(gene name synonym)|uniprotkb:KIAA1251(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000361689|ensembl:ENSP00000354573|ensembl:ENSG00000127603|refseq:NP_036222.3|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051011"(microtubule minus-end binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0150011"(regulation of neuron projection arborization)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Z6G|rcsb pdb:5VE9|rcsb pdb:5X57|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030177"(positive regulation of Wnt signaling pathway)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0042060"(wound healing)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|dip:DIP-50616N|mint:Q9UPN3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:G5PesqPZZxQhwDgW0pBJSkJNcZ49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14739 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1055147|uniprotkb:Q14740|uniprotkb:Q53GU7|uniprotkb:Q59FE6|uniprotkb:B2R5P3|ensembl:ENSP00000272163|ensembl:ENSP00000339883 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lbr_human(display_long)|uniprotkb:Integral nuclear envelope inner membrane protein(gene name synonym)|uniprotkb:LMN2R(gene name synonym)|uniprotkb:LBR(gene name)|psi-mi:LBR(display_short)|uniprotkb:"3-beta-hydroxysterol Delta (14)-reductase"(gene name synonym)|uniprotkb:C-14 sterol reductase(gene name synonym)|uniprotkb:Lamin-B receptor(gene name synonym)|uniprotkb:Sterol C14-reductase(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002287.2|refseq:NP_919424.1|refseq:XP_011542487.1|ensembl:ENSP00000272163|ensembl:ENSP00000339883|ensembl:ENSG00000143815(gene)|ensembl:ENST00000272163(transcript)|ensembl:ENST00000338179(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005521"(lamin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005639"(integral component of nuclear inner membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006695"(cholesterol biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|rcsb pdb:2DIG|reactome:R-HSA-191273|reactome:R-HSA-2995383|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9022692|go:"GO:0016126"(sterol biosynthetic process)|go:"GO:0016627"(oxidoreductase activity, acting on the CH-CH group of donors)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0031965"(nuclear membrane)|go:"GO:0050613"(delta14-sterol reductase activity)|go:"GO:0070087"(chromo shadow domain binding)|go:"GO:0070402"(NADPH binding)|interpro:IPR001171(ERG4/ERG24 ergosterol biosynthesis protein)|interpro:IPR002999(Tudor)|interpro:IPR018083|interpro:IPR019023|mint:Q14739|dip:DIP-5987N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ns5qFZb8njsTOK90hIddW2O+uQI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P40189 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1030834|uniprotkb:Q9UQ41|ensembl:ENSP00000338799|ensembl:ENSP00000370698|ensembl:ENSP00000462158|uniprotkb:A0N0L4|uniprotkb:Q5FC04 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:il6rb_human(display_long)|uniprotkb:IL6ST(gene name)|psi-mi:IL6ST(display_short)|uniprotkb:Interleukin-6 signal transducer(gene name synonym)|uniprotkb:Membrane glycoprotein 130(gene name synonym)|uniprotkb:CDw130(gene name synonym)|uniprotkb:Oncostatin-M receptor subunit alpha(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000134352(gene)|ensembl:ENST00000336909(transcript)|ensembl:ENST00000381298(transcript)|ensembl:ENST00000502326(transcript)|go:"GO:0002675"(positive regulation of acute inflammatory response)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0004896"(cytokine receptor activity)|go:"GO:0004897"(ciliary neurotrophic factor receptor activity)|go:"GO:0004921"(interleukin-11 receptor activity)|go:"GO:0005127"(ciliary neurotrophic factor receptor binding)|refseq:NP_002175.2|refseq:NP_786943.1|rcsb pdb:1BJ8|rcsb pdb:1BQU|rcsb pdb:1I1R|rcsb pdb:1N2Q|rcsb pdb:1P9M|rcsb pdb:1PVH|rcsb pdb:3L5H|rcsb pdb:3L5I|rcsb pdb:3L5J|reactome:R-HSA-1059683|reactome:R-HSA-110056|reactome:R-HSA-112411|reactome:R-HSA-6788467|reactome:R-HSA-8984722|reactome:R-HSA-9020956|go:"GO:0034097"(response to cytokine)|go:"GO:0038165"(oncostatin-M-mediated signaling pathway)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042531"(positive regulation of tyrosine phosphorylation of STAT protein)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045121"(membrane raft)|go:"GO:0045509"(interleukin-27 receptor activity)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048861"(leukemia inhibitory factor signaling pathway)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070104"(negative regulation of interleukin-6-mediated signaling pathway)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0070110"(ciliary neurotrophic factor receptor complex)|go:"GO:0070120"(ciliary neurotrophic factor-mediated signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1901731"(positive regulation of platelet aggregation)|interpro:IPR003529(Long hematopoietin receptor, gp130 family 2, conserved site)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR010457(Immunoglobulin C2-set-like, ligand-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015321(Interleukin-6 receptor alpha chain, binding)|interpro:IPR036116|mint:P40189|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005896"(interleukin-6 receptor complex)|go:"GO:0005900"(oncostatin-M receptor complex)|go:"GO:0005977"(glycogen metabolic process)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0016020"(membrane)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019838"(growth factor binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0019970"(interleukin-11 binding)|go:"GO:0030425"(dendrite)|refseq:NP_001177910.1|dip:DIP-95N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0DhlsbEh3ZiKomQFf+5mjd6hUOM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15056 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-310513|uniprotkb:Q5TA13|uniprotkb:Q5TA16|uniprotkb:Q5TA19|uniprotkb:Q86XK0|uniprotkb:Q8IZA8|uniprotkb:Q9H226|ensembl:ENSP00000347792 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:synj2_human(display_long)|uniprotkb:SYNJ2(gene name)|psi-mi:SYNJ2(display_short)|uniprotkb:KIAA0348(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003889.1|refseq:NP_001171559.1|refseq:XP_011534527.1|refseq:XP_006715655.1|ensembl:ENSG00000078269(gene)|ensembl:ENST00000355585(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007420"(brain development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0042995"(cell projection)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0045121"(membrane raft)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0098793"(presynapse)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR034973|interpro:IPR034974|interpro:IPR035979|interpro:IPR036691|mint:O15056|rcsb pdb:1UFW|reactome:R-HSA-1660499|reactome:R-HSA-8856828 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ADd6ytgVrfKYN9sx7EfXdb4ts0c9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NI35 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-724390|uniprotkb:O15249|uniprotkb:O43742|uniprotkb:O60833|uniprotkb:Q5VUA5|uniprotkb:Q5VUA6|uniprotkb:Q5VUA7|uniprotkb:Q5VUA8|uniprotkb:Q5VUA9|uniprotkb:Q5VUB0|uniprotkb:Q8WU78|uniprotkb:Q9H3N9|ensembl:ENSP00000360200 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:inadl_human(display_long)|uniprotkb:CIPP(gene name synonym)|uniprotkb:Channel-interacting PDZ domain-containing protein(gene name synonym)|uniprotkb:PATJ(gene name)|psi-mi:PATJ(display_short)|uniprotkb:INADL(gene name synonym)|uniprotkb:Pals1-associated tight junction protein(gene name synonym)|uniprotkb:Protein associated to tight junctions(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000360200|ensembl:ENST00000484937|ensembl:ENSP00000433669|ensembl:ENSG00000132849(gene)|ensembl:ENST00000371158(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0120192"(tight junction assembly)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR015132(L27-2)|interpro:IPR036034|interpro:IPR036892|mint:Q8NI35|rcsb pdb:1VF6|rcsb pdb:2D92|rcsb pdb:2DAZ|rcsb pdb:2DB5|rcsb pdb:2DLU|rcsb pdb:2DM8|rcsb pdb:2DMZ|rcsb pdb:2EHR|rcsb pdb:4Q2N|rcsb pdb:6IRD|reactome:R-HSA-420029 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:brzBKZb3r39w13Ds5X/1jB6YMyM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O43426 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2821539|uniprotkb:O43425|uniprotkb:O94984|uniprotkb:Q4KMR1|ensembl:ENSP00000501426 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:synj1_human(display_long)|uniprotkb:SYNJ1(gene name)|psi-mi:SYNJ1(display_short)|uniprotkb:KIAA0910(gene name synonym)|uniprotkb:Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001153774.1|refseq:NP_001153778.1|refseq:NP_003886.3|refseq:NP_982271.2|refseq:XP_016883989.1|ensembl:ENSG00000159082(gene)|ensembl:ENST00000674308(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004438"(phosphatidylinositol-3-phosphatase activity)|go:"GO:0004439"(phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity)|go:"GO:0005874"(microtubule)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0006836"(neurotransmitter transport)|go:"GO:0007420"(brain development)|go:"GO:0007612"(learning)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014015"(positive regulation of gliogenesis)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030117"(membrane coat)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0034097"(response to cytokine)|go:"GO:0034595"(phosphatidylinositol phosphate 5-phosphatase activity)|go:"GO:0034596"(phosphatidylinositol phosphate 4-phosphatase activity)|go:"GO:0043195"(terminal bouton)|go:"GO:0043647"(inositol phosphate metabolic process)|go:"GO:0043812"(phosphatidylinositol-4-phosphate phosphatase activity)|go:"GO:0043813"(phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0046855"(inositol phosphate dephosphorylation)|go:"GO:0046856"(phosphatidylinositol dephosphorylation)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0052629"(phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity)|go:"GO:0052658"(inositol-1,4,5-trisphosphate 5-phosphatase activity)|go:"GO:0061024"(membrane organization)|go:"GO:0097060"(synaptic membrane)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:1904980"(positive regulation of endosome organization)|go:"GO:1990175"(EH domain binding)|interpro:IPR000300(Inositol polyphosphate related phosphatase)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002013(Synaptojanin, N-terminal)|interpro:IPR005135(Endonuclease/exonuclease/phosphatase)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR015047(Region of unknown function DUF1866)|interpro:IPR034971|interpro:IPR034972|interpro:IPR035979|interpro:IPR036691|mint:O43426|rcsb pdb:1W80|rcsb pdb:2DNR|rcsb pdb:2VJ0|rcsb pdb:7A0V|reactome:R-HSA-1660499|reactome:R-HSA-1855183|reactome:R-HSA-1855204|reactome:R-HSA-8856828 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RA73eMbCn6F7MD0ItxF/V7QbjqM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q08174 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1223952|uniprotkb:Q8IUP2|ensembl:ENSP00000378043 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pcdh1_human(display_long)|uniprotkb:PCDH1(gene name)|psi-mi:PCDH1(display_short)|uniprotkb:Protocadherin-42(gene name synonym)|uniprotkb:Cadherin-like protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001265542.1|refseq:NP_001265544.1|refseq:NP_002578.2|refseq:NP_115796.2|ensembl:ENST00000287008|ensembl:ENSP00000287008|ensembl:ENSP00000378043|ensembl:ENSG00000156453(gene)|ensembl:ENST00000394536(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0007399"(nervous system development)|go:"GO:0030054"(cell junction)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR002126(Cadherin)|interpro:IPR013164(Cadherin, N-terminal)|interpro:IPR013585(Protocadherin)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|mint:Q08174|rcsb pdb:6BX7|rcsb pdb:6MGA|rcsb pdb:6PIM|rcsb pdb:6VFP - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Yqh1H2HOAVFNkWTdYY0mHWVL2Zo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q32MZ4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1369100|uniprotkb:O75766|uniprotkb:O75799|uniprotkb:Q32MZ5|uniprotkb:Q53T49|uniprotkb:Q6PKG2|uniprotkb:E9PGZ2|uniprotkb:Q9Y607|intact:EBI-28987401|ensembl:ENSP00000375857 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lrrf1_human(display_long)|uniprotkb:LRRFIP1(gene name)|psi-mi:LRRFIP1(display_short)|uniprotkb:GCF2(gene name synonym)|uniprotkb:TRIP(gene name synonym)|uniprotkb:TAR RNA-interacting protein(gene name synonym)|uniprotkb:GC-binding factor 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001131024.1|refseq:NP_001131025.1|refseq:NP_004726.2|ensembl:ENST00000244815|ensembl:ENSP00000244815|ensembl:ENST00000289175|ensembl:ENSP00000289175|ensembl:ENST00000308482|ensembl:ENSP00000310109|ensembl:ENSP00000375857|refseq:NP_001131022.1|ensembl:ENSG00000124831(gene)|ensembl:ENST00000392000(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003677"(DNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR019139|mint:Q32MZ4|rcsb pdb:4H22|reactome:R-HSA-1839117|reactome:R-HSA-3134973|reactome:R-HSA-5655302 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GRBGUu5k+BNhFDb4Z2B2XkQ0mcQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P46531 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-636374|uniprotkb:Q59ED8|uniprotkb:Q5SXM3|intact:EBI-28989124|ensembl:ENSP00000498587 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:notc1_human(display_long)|uniprotkb:Translocation-associated notch protein TAN-1(gene name synonym)|uniprotkb:NOTCH1(gene name)|psi-mi:NOTCH1(display_short)|uniprotkb:TAN1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060087.3|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006955"(immune response)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007221"(positive regulation of transcription of Notch receptor target)|go:"GO:0005912"(adherens junction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007368"(determination of left/right symmetry)|go:"GO:0007386"(compartment pattern specification)|go:"GO:0007411"(axon guidance)|go:"GO:0007440"(foregut morphogenesis)|go:"GO:0007492"(endoderm development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009912"(auditory receptor cell fate commitment)|go:"GO:0009986"(cell surface)|go:"GO:0010614"(negative regulation of cardiac muscle hypertrophy)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010812"(negative regulation of cell-substrate adhesion)|go:"GO:0010832"(negative regulation of myotube differentiation)|go:"GO:0014031"(mesenchymal cell development)|go:"GO:0014807"(regulation of somitogenesis)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021515"(cell differentiation in spinal cord)|go:"GO:0021915"(neural tube development)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030279"(negative regulation of ossification)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030514"(negative regulation of BMP signaling pathway)|go:"GO:0030900"(forebrain development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031960"(response to corticosteroid)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035148"(tube formation)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0042246"(tissue regeneration)|go:"GO:0042802"(identical protein binding)|go:"GO:0043086"(negative regulation of catalytic activity)|go:"GO:0043235"(receptor complex)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045608"(negative regulation of inner ear auditory receptor cell differentiation)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045662"(negative regulation of myoblast differentiation)|go:"GO:0045668"(negative regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045955"(negative regulation of calcium ion-dependent exocytosis)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046427"(positive regulation of receptor signaling pathway via JAK-STAT)|go:"GO:0046533"(negative regulation of photoreceptor cell differentiation)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0048103"(somatic stem cell division)|go:"GO:0048708"(astrocyte differentiation)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0048711"(positive regulation of astrocyte differentiation)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0048754"(branching morphogenesis of an epithelial tube)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050768"(negative regulation of neurogenesis)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0055008"(cardiac muscle tissue morphogenesis)|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060253"(negative regulation of glial cell proliferation)|go:"GO:0060271"(cilium assembly)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060354"(negative regulation of cell adhesion molecule production)|go:"GO:0060411"(cardiac septum morphogenesis)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060528"(secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development)|go:"GO:0060740"(prostate gland epithelium morphogenesis)|go:"GO:0060768"(regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0060842"(arterial endothelial cell differentiation)|go:"GO:0060843"(venous endothelial cell differentiation)|go:"GO:0060948"(cardiac vascular smooth muscle cell development)|go:"GO:0060956"(endocardial cell differentiation)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0060038"(cardiac muscle cell proliferation)|go:"GO:0072144"(glomerular mesangial cell development)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097150"(neuronal stem cell population maintenance)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:0061384"(heart trabecula morphogenesis)|go:"GO:0061419"(positive regulation of transcription from RNA polymerase II promoter in response to hypoxia)|go:"GO:1901201"(regulation of extracellular matrix assembly)|go:"GO:0062043"(positive regulation of cardiac epithelial to mesenchymal transition)|go:"GO:0070168"(negative regulation of biomineral tissue development)|go:"GO:1902263"(apoptotic process involved in embryonic digit morphogenesis)|go:"GO:1902339"(positive regulation of apoptotic process involved in morphogenesis)|go:"GO:1903849"(positive regulation of aorta morphogenesis)|go:"GO:2000048"(negative regulation of cell-cell adhesion mediated by cadherin)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2000974"(negative regulation of pro-B cell differentiation)|go:"GO:2001027"(negative regulation of endothelial cell chemotaxis)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|go:"GO:0070986"(left/right axis specification)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR010660(Notch, NOD region)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022362|interpro:IPR024600|go:"GO:0071372"(cellular response to follicle-stimulating hormone stimulus)|interpro:IPR035993|interpro:IPR036770|mint:P46531|rcsb pdb:1PB5|rcsb pdb:1TOZ|rcsb pdb:1YYH|rcsb pdb:2F8X|rcsb pdb:2F8Y|rcsb pdb:2HE0|go:"GO:0072017"(distal tubule development)|go:"GO:0072044"(collecting duct development)|rcsb pdb:2VJ3|rcsb pdb:3ETO|rcsb pdb:3I08|rcsb pdb:3L95|rcsb pdb:3NBN|rcsb pdb:3V79|rcsb pdb:4CUD|rcsb pdb:4CUE|rcsb pdb:4CUF|rcsb pdb:4D0E|rcsb pdb:4D0F|rcsb pdb:5FM9|rcsb pdb:5FMA|rcsb pdb:5KZO|rcsb pdb:5L0R|rcsb pdb:5UB5|rcsb pdb:6IDF|rcsb pdb:6PY8|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-210744|reactome:R-HSA-2122947|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2644607|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-8941856|reactome:R-HSA-9013508|reactome:R-HSA-9013695|ensembl:ENSG00000148400(gene)|ensembl:ENST00000651671(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001889"(liver development)|go:"GO:0001947"(heart looping)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002193"(MAML1-RBP-Jkappa- ICN1 complex)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003157"(endocardium development)|go:"GO:0003160"(endocardium morphogenesis)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003169"(coronary vein morphogenesis)|go:"GO:0003180"(aortic valve morphogenesis)|go:"GO:0003181"(atrioventricular valve morphogenesis)|go:"GO:0003182"(coronary sinus valve morphogenesis)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0003192"(mitral valve formation)|go:"GO:0003198"(epithelial to mesenchymal transition involved in endocardial cushion formation)|go:"GO:0003203"(endocardial cushion morphogenesis)|go:"GO:0003207"(cardiac chamber formation)|go:"GO:0003208"(cardiac ventricle morphogenesis)|go:"GO:0003209"(cardiac atrium morphogenesis)|go:"GO:0003213"(cardiac right atrium morphogenesis)|go:"GO:0003214"(cardiac left ventricle morphogenesis)|go:"GO:0003219"(cardiac right ventricle formation)|go:"GO:0003222"(ventricular trabecula myocardium morphogenesis)|go:"GO:0003241"(growth involved in heart morphogenesis)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0003256"(regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation)|go:"GO:0003270"(Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation)|go:"GO:0003273"(cell migration involved in endocardial cushion formation)|go:"GO:0003332"(negative regulation of extracellular matrix constituent secretion)|go:"GO:0003344"(pericardium morphogenesis)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|dip:DIP-29919N|ensembl:ENSP00000498587 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yRAjMjynnyZ7ANlk2eulodpS4P09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P42356 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-723050|uniprotkb:Q7Z625|uniprotkb:Q9UPG2|ensembl:ENSP00000255882|intact:EBI-11053324 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pi4ka_human(display_long)|uniprotkb:PIK4CA(gene name synonym)|uniprotkb:PI4KA(gene name)|psi-mi:PI4KA(display_short)|uniprotkb:PIK4(gene name synonym)|uniprotkb:Phosphatidylinositol 4-Kinase III alpha(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000241973(gene)|ensembl:ENST00000255882(transcript)|go:"GO:0004430"(1-phosphatidylinositol 4-kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006661"(phosphatidylinositol biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016310"(phosphorylation)|go:"GO:0030660"(Golgi-associated vesicle membrane)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0044803"(multi-organism membrane organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0046786"(viral replication complex formation and maintenance)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0052742"(phosphatidylinositol kinase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000403(Phosphatidylinositol 3- and 4-kinase, catalytic)|interpro:IPR001263(Phosphoinositide 3-kinase accessory region PIK)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015433(Phosphatidylinositol Kinase)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR018936|interpro:IPR036940|interpro:IPR042236|rcsb pdb:6BQ1|reactome:R-HSA-1483248|reactome:R-HSA-1660514|go:"GO:0016301"(kinase activity)|refseq:NP_477352.3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:tm7wwZPJEvFMfK9xHMPLW9oYtzk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6ZRV2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2556538|intact:EBI-2558430|uniprotkb:Q8N4W0|uniprotkb:A0JLS2|intact:EBI-28968834|ensembl:ENSP00000373565|ensembl:ENSP00000478790 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:fa83h_human(display_long)|uniprotkb:FAM83H(gene name)|psi-mi:FAM83H(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_940890.3|ensembl:ENSP00000373565|ensembl:ENSP00000478790|ensembl:ENSG00000180921(gene)|ensembl:ENSG00000273889(gene)|ensembl:ENST00000388913(transcript)|ensembl:ENST00000612192(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007165"(signal transduction)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:1990254"(keratin filament binding)|interpro:IPR012461(Protein of unknown function DUF1669)|go:"GO:0030335"(positive regulation of cell migration)|interpro:IPR041996|go:"GO:0031214"(biomineral tissue development)|mint:Q6ZRV2|go:"GO:0044380"(protein localization to cytoskeleton)|go:"GO:0019901"(protein kinase binding)|refseq:XP_005250946.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:CraAR+g1L497ZXCuetDTOHn8rUA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P26196 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351257|uniprotkb:Q5D048|ensembl:ENSP00000433704|ensembl:ENSP00000442266|ensembl:ENSP00000478754 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ddx6_human(display_long)|uniprotkb:DDX6(gene name)|psi-mi:DDX6(display_short)|uniprotkb:HLR2(gene name synonym)|uniprotkb:RCK(gene name synonym)|uniprotkb:DEAD box protein 6(gene name synonym)|uniprotkb:ATP-dependent RNA helicase p54(gene name synonym)|uniprotkb:Oncogene RCK(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004388.2|refseq:NP_001244120.1|ensembl:ENSG00000110367(gene)|ensembl:ENST00000526070(transcript)|ensembl:ENST00000534980(transcript)|ensembl:ENST00000620157(transcript)|go:"GO:0000792"(heterochromatin)|go:"GO:0000932"(P-body)|go:"GO:0001520"(outer dense fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0004386"(helicase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019074"(viral RNA genome packaging)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0033391"(chromatoid body)|go:"GO:0033962"(P-body assembly)|go:"GO:0034063"(stress granule assembly)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0045296"(cadherin binding)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048515"(spermatid differentiation)|go:"GO:0061830"(concave side of sperm head)|go:"GO:0097227"(sperm annulus)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|interpro:IPR000629(RNA helicase, ATP-dependent, DEAD-box, conserved site)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR014014(RNA helicase, DEAD-box type, Q motif)|interpro:IPR027417|mint:P26196|rcsb pdb:1VEC|rcsb pdb:2WAX|rcsb pdb:2WAY|rcsb pdb:4CRW|rcsb pdb:4CT4|rcsb pdb:4CT5|rcsb pdb:5ANR|rcsb pdb:6F9S|rcsb pdb:6S8S|reactome:R-HSA-430039|refseq:XP_005271474.1|dip:DIP-29195N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:pBOpwnVU+BmxUyC/uo2ig53QRto9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O43795 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351119|uniprotkb:O43794|uniprotkb:Q7Z6L5|ensembl:ENSP00000306382|ensembl:ENSP00000376132 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:myo1b_human(display_long)|uniprotkb:MYO1B(gene name)|psi-mi:MYO1B(display_short)|uniprotkb:Myosin I alpha(gene name synonym)|uniprotkb:MYH-1c(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001123630.1|refseq:NP_001155291.1|refseq:NP_036355.2|ensembl:ENSG00000128641(gene)|ensembl:ENST00000304164(transcript)|ensembl:ENST00000392318(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0010008"(endosome membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030175"(filopodium)|go:"GO:0031982"(vesicle)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR010926(Myosin tail 2)|interpro:IPR027417|interpro:IPR036072|interpro:IPR036961|mint:O43795|go:"GO:0016459"(myosin complex)|refseq:XP_005246629.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:FYYccaCMhkmUdTdtq4M8zdpFpV89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q01970 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4289548|uniprotkb:A5PKZ6|ensembl:ENSP00000279230|ensembl:ENSP00000443631|uniprotkb:G5E960|uniprotkb:Q8N1A4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:plcb3_human(display_long)|uniprotkb:PLCB3(gene name)|psi-mi:PLCB3(display_short)|uniprotkb:Phosphoinositide phospholipase C-beta-3(gene name synonym)|uniprotkb:Phospholipase C-beta-3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000923.1|ensembl:ENSG00000149782(gene)|ensembl:ENST00000279230(transcript)|ensembl:ENST00000540288(transcript)|go:"GO:0003073"(regulation of systemic arterial blood pressure)|go:"GO:0004435"(phosphatidylinositol phospholipase C activity)|go:"GO:0004629"(phospholipase C activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0016020"(membrane)|go:"GO:0016042"(lipid catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046488"(phosphatidylinositol metabolic process)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0099524"(postsynaptic cytosol)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000909(Phospholipase C, phosphatidylinositol-specific , X region)|interpro:IPR001192("Phospholipase C, phosphoinositol-specific, C-terminal (PLC)")|interpro:IPR001711(Phospholipase C, phosphatidylinositol-specific, Y domain)|interpro:IPR011992(EF-Hand type)|interpro:IPR014815(PLC-beta, C-terminal)|interpro:IPR015359(Phospholipase C, phosphoinositol-specific, EF-hand-like)|interpro:IPR016280(Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase beta)|interpro:IPR017946|interpro:IPR035892|interpro:IPR037862|interpro:IPR042531|rcsb pdb:3OHM|rcsb pdb:4GNK|rcsb pdb:4QJ3|rcsb pdb:4QJ4|rcsb pdb:4QJ5|reactome:R-HSA-112043|reactome:R-HSA-1855204|reactome:R-HSA-399997|reactome:R-HSA-4086398|reactome:R-HSA-416476|reactome:R-HSA-418217|reactome:R-HSA-434316|reactome:R-HSA-500657|refseq:NP_001171812.1|refseq:NP_001303243.1|dip:DIP-41928N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ilIX1O1btxVzzYNb7iW4dG+Yh789606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BQL6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4403029|uniprotkb:D3DW10|uniprotkb:Q8IX34|uniprotkb:Q8IYH2|uniprotkb:Q9NWM2|uniprotkb:Q9NXQ3|ensembl:ENSP00000217289 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ferm1_human(display_long)|uniprotkb:FERMT1(gene name)|psi-mi:FERMT1(display_short)|uniprotkb:C20orf42(gene name synonym)|uniprotkb:KIND1(gene name synonym)|uniprotkb:URP1(gene name synonym)|uniprotkb:Kindlerin(gene name synonym)|uniprotkb:Kindlin syndrome protein(gene name synonym)|uniprotkb:Kindlin-1(gene name synonym)|uniprotkb:Unc-112-related protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060141.3|ensembl:ENSG00000101311(gene)|ensembl:ENST00000217289(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0030054"(cell junction)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0033630"(positive regulation of cell adhesion mediated by integrin)|go:"GO:0042308"(negative regulation of protein import into nucleus)|go:"GO:0043616"(keratinocyte proliferation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051546"(keratinocyte migration)|go:"GO:0051886"(negative regulation of timing of anagen)|go:"GO:0071636"(positive regulation of transforming growth factor beta production)|go:"GO:0071711"(basement membrane organization)|go:"GO:0071944"(cell periphery)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:1903691"(positive regulation of wound healing, spreading of epidermal cells)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR019748|interpro:IPR019749|interpro:IPR035963|interpro:IPR037843|interpro:IPR037837|interpro:IPR040790 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lfWyDOEGRWkHX1dFHQ+F1PEukU89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q16513 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2511350|uniprotkb:Q9H1W4|uniprotkb:D3DT24|uniprotkb:B4DQ21|uniprotkb:B4DTP5|uniprotkb:B4DVG1|uniprotkb:Q08AF4|ensembl:ENSP00000359552 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkn2_human(display_long)|uniprotkb:PKN2(gene name)|psi-mi:PKN2(display_short)|uniprotkb:PRK2(gene name synonym)|uniprotkb:PRKCL2(gene name synonym)|uniprotkb:Protein kinase C-like 2(gene name synonym)|uniprotkb:Protein-kinase C-related kinase 2(gene name synonym)|uniprotkb:PKN gamma(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011540074.1|refseq:NP_006247.1|refseq:NP_001307636.1|refseq:NP_001307637.1|refseq:NP_001307638.1|ensembl:ENSG00000065243(gene)|ensembl:ENST00000370521(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004698"(calcium-dependent protein kinase C activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0010631"(epithelial cell migration)|go:"GO:0016301"(kinase activity)|go:"GO:0016604"(nuclear body)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030496"(midbody)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032154"(cleavage furrow)|go:"GO:0005654"(nucleoplasm)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0043297"(apical junction assembly)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0045931"(positive regulation of mitotic cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051301"(cell division)|go:"GO:0070063"(RNA polymerase binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000145"(regulation of cell motility)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|interpro:IPR035892|interpro:IPR036274|interpro:IPR037313|interpro:IPR037784|mint:Q16513|rcsb pdb:4CRS|rcsb pdb:4RRV|rcsb pdb:6CCY|rcsb pdb:6GBE|reactome:R-HSA-5625740|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013149|go:"GO:0032467"(positive regulation of cytokinesis) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:KvHDOJ75CgHIGDC+41jGKORm2+w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P15170 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NSV4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1050601|uniprotkb:A2A3B8|uniprotkb:A2A3B9|uniprotkb:A2A3C0|uniprotkb:Q18P99|uniprotkb:Q18PA0|uniprotkb:Q18PA1|uniprotkb:Q2KPB6|uniprotkb:Q3ZK23|uniprotkb:Q5JTP8|uniprotkb:Q5T2S7|uniprotkb:Q5XKF6|uniprotkb:Q6MZF0|uniprotkb:Q6NUP0|uniprotkb:Q86VS4|uniprotkb:Q8NAV4|ensembl:ENSP00000383178 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:diap3_human(display_long)|uniprotkb:Diaphanous-related formin-3(gene name synonym)|uniprotkb:DIAPH3(gene name)|psi-mi:DIAPH3(display_short)|uniprotkb:DIAP3(gene name synonym)|uniprotkb:MDia2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001035982.1|refseq:NP_112194.2|refseq:NP_001245295.1|refseq:NP_001245296.1|refseq:NP_001245297.1|refseq:NP_001245298.1|refseq:NP_001245299.1|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|ensembl:ENSG00000139734(gene)|ensembl:ENST00000400324(transcript)|go:"GO:0045296"(cadherin binding)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014767(Diaphanous autoregulatory)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR027654|interpro:IPR042201|interpro:IPR010465(DRF autoregulatory)|mint:Q9NSV4|rcsb pdb:5UWP|rcsb pdb:6X2Y|reactome:R-HSA-5663220|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:noy8LGt6F+8an19X1WyEqSqpAYk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96JH7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1995920|uniprotkb:Q504T4|uniprotkb:Q86T93|uniprotkb:Q86W01|uniprotkb:Q8N3A9|uniprotkb:Q9H5R8|ensembl:ENSP00000309031 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vcip1_human(display_long)|uniprotkb:VCPIP1(gene name)|psi-mi:VCPIP1(display_short)|uniprotkb:KIAA1850(gene name synonym)|uniprotkb:VCIP135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein p135(gene name synonym)|uniprotkb:Valosin-containing protein p97/p47 complex-interacting protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_079330.2|ensembl:ENSG00000175073(gene)|ensembl:ENST00000310421(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005795"(Golgi stack)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0016320"(endoplasmic reticulum membrane fusion)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0035871"(protein K11-linked deubiquitination)|go:"GO:0071108"(protein K48-linked deubiquitination)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0106300"(protein-DNA covalent cross-linking repair)|go:"GO:1905634"(regulation of protein localization to chromatin)|interpro:IPR003323(Ovarian tumour, otubain)|interpro:IPR029071|interpro:IPR039087|mint:Q96JH7|reactome:R-HSA-5689896 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:EMqKXIMqv42Vlg5oUS+kT9WI5BQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P28290 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-722905|uniprotkb:Q8N7H2|uniprotkb:Q7Z7L2|uniprotkb:Q8N1L3|uniprotkb:Q8N263|uniprotkb:Q8NEN5|uniprotkb:Q96E36|uniprotkb:Q68DA6|uniprotkb:Q96PW1|uniprotkb:A8K6T0|intact:EBI-28986959|ensembl:ENSP00000388731 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:itpi2_human(display_long)|uniprotkb:ITPRID2(gene name)|psi-mi:ITPRID2(display_short)|uniprotkb:CS1(gene name synonym)|uniprotkb:Cleavage signal-1 protein(gene name synonym)|uniprotkb:ITPR-interacting domain-containing protein 2(gene name synonym)|uniprotkb:KIAA1927(gene name synonym)|uniprotkb:KRAP(gene name synonym)|uniprotkb:Ki-ras-induced actin-interacting protein(gene name synonym)|uniprotkb:SSFA2(gene name synonym)|uniprotkb:Sperm-specific antigen 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001123917.1|refseq:NP_006742.2|refseq:NP_001274432.1|refseq:NP_001274433.1|ensembl:ENST00000320370|ensembl:ENSP00000314669|ensembl:ENSP00000388731|dip:DIP-47271N|ensembl:ENSG00000138434(gene)|ensembl:ENST00000431877(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0051015"(actin filament binding)|interpro:IPR026648|interpro:IPR029325|interpro:IPR029326|interpro:IPR043444 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:oLYBDg++fr2C4VnIkkP5xhll5dw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y6E2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1051021|uniprotkb:Q3B779|uniprotkb:Q9H3F7|uniprotkb:A4D123|uniprotkb:Q96JW5|ensembl:ENSP00000258761|ensembl:ENSP00000397249 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:bzw2_human(display_long)|uniprotkb:BZW2(gene name)|psi-mi:BZW2(display_short)|uniprotkb:HSPC028(orf name)|uniprotkb:MSTP017(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001153239.1|refseq:NP_054757.1|ensembl:ENSG00000136261(gene)|ensembl:ENST00000258761(transcript)|ensembl:ENST00000433922(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0045296"(cadherin binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR043510|refseq:XP_006715769.1|refseq:XP_006715770.1|refseq:XP_006715771.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+z22Ykb6e3IM9zk51m6tjuhiEcU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P20810 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1268770|uniprotkb:G5E9D3|uniprotkb:O95360|uniprotkb:Q96D08|uniprotkb:Q9H1Z5|uniprotkb:Q7Z4K0|intact:EBI-11042429|uniprotkb:B7Z468|uniprotkb:Q05DE8|uniprotkb:G5E946|ensembl:ENSP00000339914|ensembl:ENSP00000379158 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ical_human(display_long)|uniprotkb:CAST(gene name)|psi-mi:CAST(display_short)|uniprotkb:Calpain inhibitor(gene name synonym)|uniprotkb:Sperm BS-17 component(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001035905.1|refseq:XP_006714759.1|refseq:XP_006714766.1|refseq:NP_001271141.1|refseq:XP_006714764.1|refseq:NP_001035906.1|refseq:NP_001035907.1|refseq:NP_001035908.1|refseq:NP_001035909.1|refseq:NP_001317560.1|refseq:NP_001741.4|refseq:XP_016865402.1|go:"GO:2000675"(negative regulation of type B pancreatic cell apoptotic process)|interpro:IPR001259(Proteinase inhibitor I27, calpastatin)|interpro:IPR026998|mint:P20810|reactome:R-HSA-1474228|reactome:R-HSA-8862803|go:"GO:1990709"(presynaptic active zone organization)|ensembl:ENSG00000153113(gene)|ensembl:ENST00000341926(transcript)|ensembl:ENST00000395813(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004866"(endopeptidase inhibitor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0010859"(calcium-dependent cysteine-type endopeptidase inhibitor activity)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0097340"(inhibition of cysteine-type endopeptidase activity)|refseq:NP_775083.1|refseq:XP_006714767.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:sDc8/o13gLhr18fYsz/grYg13Lo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NU19 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-8787464|uniprotkb:Q32MQ8|uniprotkb:Q5VUK9|uniprotkb:Q7Z6P7|uniprotkb:Q9BPV6|uniprotkb:Q9BUT5|uniprotkb:Q9NXB6|uniprotkb:A8KA28|uniprotkb:Q6P4C3|ensembl:ENSP00000362590 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tb22b_human(display_long)|uniprotkb:TBC1D22B(gene name)|psi-mi:TBC1D22B(display_short)|uniprotkb:C6orf197(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060242.2|ensembl:ENSG00000065491(gene)|ensembl:ENST00000373491(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|rcsb pdb:6D0S - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7HsT3sqT4dWazVEhXGfOz2fcau09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P55011 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2801449|uniprotkb:Q8WWH7|uniprotkb:Q8N713|intact:EBI-28983018|ensembl:ENSP00000262461 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:s12a2_human(display_long)|uniprotkb:NKCC1(gene name synonym)|uniprotkb:Basolateral Na-K-Cl symporter(gene name synonym)|uniprotkb:SLC12A2(gene name)|psi-mi:SLC12A2(display_short)|uniprotkb:"Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2"(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000262461|ensembl:ENST00000343225|ensembl:ENSP00000340878|refseq:NP_001037.1|ensembl:ENSG00000064651(gene)|ensembl:ENST00000262461(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006972"(hyperosmotic response)|go:"GO:0007214"(gamma-aminobutyric acid signaling pathway)|go:"GO:0007568"(aging)|go:"GO:0008511"("sodium:potassium:chloride symporter activity")|go:"GO:0008519"(ammonium transmembrane transporter activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0015079"(potassium ion transmembrane transporter activity)|go:"GO:0015377"("cation:chloride symporter activity")|go:"GO:0015379"("potassium:chloride symporter activity")|go:"GO:0015696"|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030007"(cellular potassium ion homeostasis)|go:"GO:0030321"(transepithelial chloride transport)|go:"GO:0030644"(cellular chloride ion homeostasis)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035725"(sodium ion transmembrane transport)|go:"GO:0035865"(cellular response to potassium ion)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0044297"(cell body)|go:"GO:0044298"(cell body membrane)|go:"GO:0045795"(positive regulation of cell volume)|go:"GO:0046873"(metal ion transmembrane transporter activity)|go:"GO:0051087"(chaperone binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0055064"(chloride ion homeostasis)|go:"GO:0055075"(potassium ion homeostasis)|go:"GO:0055078"(sodium ion homeostasis)|go:"GO:0061044"(negative regulation of vascular wound healing)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070634"(transepithelial ammonium transport)|go:"GO:0071944"(cell periphery)|go:"GO:0098658"(inorganic anion import across plasma membrane)|go:"GO:0098659"(inorganic cation import across plasma membrane)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902476"(chloride transmembrane transport)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904450"(positive regulation of aspartate secretion)|go:"GO:1904464"(regulation of matrix metallopeptidase secretion)|go:"GO:1990573"(potassium ion import across plasma membrane)|go:"GO:1990869"(cellular response to chemokine)|go:"GO:0042995"(cell projection)|interpro:IPR002444(Na-K-Cl co-transporter 1)|interpro:IPR004841(Amino acid permease-associated region)|interpro:IPR004842(Na-K-Cl cotransporter superfamily)|interpro:IPR013612(Amino acid permease N-terminal)|interpro:IPR018491|mint:P55011|rcsb pdb:6PZT|rcsb pdb:7D10|reactome:R-HSA-426117|interpro:IPR002443(Na-K-Cl co-transporter)|dip:DIP-43979N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:DJ/f5e8b/aBlnCcWYxYUa/mcoFY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q99959 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-702235|intact:EBI-2692870|uniprotkb:D3DUW9|uniprotkb:Q99960|uniprotkb:Q4VC01|uniprotkb:B8QFA1|uniprotkb:B8QGS6|uniprotkb:B8QGS7|uniprotkb:A0AV37|ensembl:ENSP00000070846 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkp2_human(display_long)|uniprotkb:PKP2(gene name)|psi-mi:PKP2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004563.2|refseq:NP_001005242.2|ensembl:ENSG00000057294(gene)|ensembl:ENST00000070846(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002159"(desmosome assembly)|go:"GO:0002934"(desmosome organization)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007507"(heart development)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045110"(intermediate filament bundle assembly)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048496"(maintenance of animal organ identity)|go:"GO:0055010"(ventricular cardiac muscle tissue morphogenesis)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086002"(cardiac muscle cell action potential involved in contraction)|go:"GO:0086005"(ventricular cardiac muscle cell action potential)|go:"GO:0086019"(cell-cell signaling involved in cardiac conduction)|go:"GO:0086064"(cell communication by electrical coupling involved in cardiac conduction)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|mint:Q99959|rcsb pdb:3TT9|reactome:R-HSA-6805567|reactome:R-HSA-6809371 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:kwGWMlk4SDz0xARlBMD1dY9fehQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y2J2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-310986|uniprotkb:O95713|uniprotkb:Q9BRP5|ensembl:ENSP00000343158|uniprotkb:B7Z4I5|uniprotkb:F5GX05 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:e41l3_human(display_long)|uniprotkb:EPB41L3(gene name)|psi-mi:EPB41L3(display_short)|uniprotkb:DAL1(gene name synonym)|uniprotkb:KIAA0987(gene name synonym)|uniprotkb:4.1B(gene name synonym)|uniprotkb:Differentially expressed in adenocarcinoma of the lung protein 1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_036439.2|refseq:NP_001268462.1|refseq:NP_001268463.1|refseq:NP_001268464.1|ensembl:ENSG00000082397(gene)|ensembl:ENST00000341928(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0002175"(protein localization to paranode region of axon)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006915"(apoptotic process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0030054"(cell junction)|go:"GO:0030865"(cortical cytoskeleton organization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030913"(paranodal junction assembly)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0033270"(paranode region of axon)|go:"GO:0043217"(myelin maintenance)|go:"GO:0044224"(juxtaparanode region of axon)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0071205"(protein localization to juxtaparanode region of axon)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030691|interpro:IPR035963|mint:Q9Y2J2|rcsb pdb:2HE7|rcsb pdb:3BIN|rcsb pdb:5RYM|rcsb pdb:5RYN|rcsb pdb:5RYO|rcsb pdb:5RYP|rcsb pdb:5RYQ|rcsb pdb:5RYR|rcsb pdb:5RYS|rcsb pdb:5RYT|rcsb pdb:5RYU|rcsb pdb:5RYV|rcsb pdb:5RYW|rcsb pdb:5RYX|rcsb pdb:5RYY|rcsb pdb:5RYZ|rcsb pdb:5RZ0|rcsb pdb:5RZ1|rcsb pdb:5RZ2|rcsb pdb:5RZ3|rcsb pdb:5RZ4|rcsb pdb:5RZ5|rcsb pdb:5RZ6|rcsb pdb:5RZ7|rcsb pdb:5RZ8|rcsb pdb:5RZ9|rcsb pdb:5RZA|rcsb pdb:5RZB|rcsb pdb:5RZC|rcsb pdb:5RZD|rcsb pdb:5RZE|rcsb pdb:5RZF|rcsb pdb:5RZG|rcsb pdb:5RZH|rcsb pdb:5RZI|rcsb pdb:5RZJ|rcsb pdb:5RZK|rcsb pdb:5RZL|rcsb pdb:5RZM|rcsb pdb:5RZN|rcsb pdb:5RZO|rcsb pdb:5RZP|rcsb pdb:5RZQ|rcsb pdb:5RZR|rcsb pdb:5RZS|rcsb pdb:5RZT|rcsb pdb:5RZU|rcsb pdb:5RZV|rcsb pdb:5RZW|rcsb pdb:5RZX|rcsb pdb:5RZY|rcsb pdb:5RZZ|rcsb pdb:5S00|rcsb pdb:6IBE|reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:XP_016881125.1|dip:DIP-17035N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Uwq5dqLRdgFLPBhXZROSRJstl709606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:A1X283 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2481776|uniprotkb:B6F0V2|uniprotkb:Q9P2Q1|ensembl:ENSP00000309714 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:spd2b_human(display_long)|uniprotkb:Tyrosine kinase substrate with four SH3 domains(gene name synonym)|uniprotkb:SH3PXD2B(gene name)|psi-mi:SH3PXD2B(display_short)|uniprotkb:FAD49(gene name synonym)|uniprotkb:KIAA1295(gene name synonym)|uniprotkb:Adapter protein HOFI(gene name synonym)|uniprotkb:Factor for adipocyte differentiation 49(gene name synonym)|uniprotkb:TKS4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0042995"(cell projection)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060348"(bone development)|go:"GO:0060612"(adipose tissue development)|go:"GO:0071800"(podosome assembly)|go:"GO:0072657"(protein localization to membrane)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR030512|interpro:IPR035477|interpro:IPR035478|interpro:IPR035479|go:"GO:0042169"(SH2 domain binding)|interpro:IPR035480|interpro:IPR036028|interpro:IPR036871|ensembl:ENSG00000174705(gene)|ensembl:ENST00000311601(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001654"(eye development)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0007507"(heart development)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0016176"(superoxide-generating NADPH oxidase activator activity)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|mint:A1X283|interpro:IPR037961|refseq:NP_001017995.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GOhZr1suKq2v9mpmOmA774KvEBg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14008 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-310585|uniprotkb:Q0VAX8|uniprotkb:Q14668|uniprotkb:Q05D70|uniprotkb:Q0VAX7|uniprotkb:Q2TA89|uniprotkb:Q6NSH4|intact:EBI-28968667|ensembl:ENSP00000432768 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ckap5_human(display_long)|uniprotkb:CKAP5(gene name)|psi-mi:CKAP5(display_short)|uniprotkb:KIAA0097(gene name synonym)|uniprotkb:Colonic and hepatic tumor overexpressed gene protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000312055|ensembl:ENSP00000310227|ensembl:ENST00000354558|ensembl:ENSP00000346566|ensembl:ENSP00000432768|refseq:NP_001008938.1|refseq:NP_055571.2|ensembl:ENSG00000175216(gene)|ensembl:ENST00000529230(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0000922"(spindle pole)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007019"(microtubule depolymerization)|go:"GO:0007051"(spindle organization)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0016020"(membrane)|go:"GO:0030951"(establishment or maintenance of microtubule cytoskeleton polarity)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0050658"(RNA transport)|go:"GO:0051298"(centrosome duplication)|go:"GO:0051301"(cell division)|go:"GO:0061863"(microtubule plus end polymerase)|go:"GO:0090063"(positive regulation of microtubule nucleation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR024395|interpro:IPR034085|mint:Q14008|rcsb pdb:4QMI|rcsb pdb:4QMJ|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9648025 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3bgwyNEucxXwXdbxbJkJ07PC90w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UNZ2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-721577|uniprotkb:Q7Z533|uniprotkb:Q9H102|uniprotkb:Q9NVL9|uniprotkb:Q9UI06|uniprotkb:Q5JXA5|uniprotkb:B2RD74|uniprotkb:Q5JXA4|uniprotkb:A2A2L1|ensembl:ENSP00000216879 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nsf1c_human(display_long)|uniprotkb:p97 cofactor p47(gene name synonym)|uniprotkb:NSFL1C(gene name)|psi-mi:NSFL1C(display_short)|uniprotkb:UBXN2C(gene name synonym)|uniprotkb:UBX domain-containing protein 2C(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001193665.1|refseq:NP_057227.2|refseq:NP_061327.2|dip:DIP-39611N|refseq:XP_006723657.1|go:"GO:0000132"(establishment of mitotic spindle orientation)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005694"(chromosome)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031616"(spindle pole centrosome)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0051117"(ATPase binding)|go:"GO:0061025"(membrane fusion)|go:"GO:1904780"(negative regulation of protein localization to centrosome)|go:"GO:1990730"(VCP-NSFL1C complex)|interpro:IPR001012(UBX)|interpro:IPR009060(UBA-like)|interpro:IPR012989(SEP)|interpro:IPR029071|interpro:IPR036241|mint:Q9UNZ2|rcsb pdb:1SS6|reactome:R-HSA-9013407|go:"GO:0000045"(autophagosome assembly)|ensembl:ENSG00000088833(gene)|ensembl:ENST00000216879(transcript) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:LhK56TmbnfHvffJ2WUFlJJepje89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q68DA7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4407407|uniprotkb:Q3B7I6|uniprotkb:Q3ZAR4|uniprotkb:Q6ZSY1|ensembl:ENSP00000479134 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:fmn1_human(display_long)|uniprotkb:FMN1(gene name)|psi-mi:FMN1(display_short)|uniprotkb:FMN(gene name synonym)|uniprotkb:LD(gene name synonym)|uniprotkb:Limb deformity protein homolog(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001096654.1|refseq:XP_011519806.1|refseq:NP_001264242.1|refseq:NP_001264243.1|ensembl:ENST00000320930|ensembl:ENSP00000325166|ensembl:ENST00000334528|ensembl:ENSP00000333950|ensembl:ENST00000558197|ensembl:ENSP00000452984|ensembl:ENSP00000479134|refseq:XP_016877619.1|ensembl:ENSG00000248905(gene)|ensembl:ENST00000616417(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0008017"(microtubule binding)|go:"GO:0010467"(gene expression)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0035136"(forelimb morphogenesis)|go:"GO:0035137"(hindlimb morphogenesis)|go:"GO:0045010"(actin nucleation)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0051127"(positive regulation of actin nucleation)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0072092"(ureteric bud invasion)|interpro:IPR001265(Formin)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR042201 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:bMy96kw1wdShaL+xw/XrqV+m9TU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NQW6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2553589|uniprotkb:Q9H8Y4|uniprotkb:Q6NSK5|uniprotkb:Q9NVP0|uniprotkb:Q9NVN9|uniprotkb:Q5CZ78|ensembl:ENSP00000265748 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:anln_human(display_long)|uniprotkb:ANLN(gene name)|psi-mi:ANLN(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001271230.1|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0007096"(regulation of exit from mitosis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030496"(midbody)|go:"GO:0031106"(septin ring organization)|go:"GO:0032059"(bleb)|go:"GO:0045296"(cadherin binding)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:0099738"(cell cortex region)|go:"GO:1904172"(positive regulation of bleb assembly)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR012966(Protein of unknown function DUF1709, fungi)|interpro:IPR031970|interpro:IPR037840|rcsb pdb:2Y7B|rcsb pdb:4XH3|rcsb pdb:4XOI|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|go:"GO:0005654"(nucleoplasm)|ensembl:ENSG00000011426(gene)|ensembl:ENST00000265748(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000915"(actomyosin contractile ring assembly)|go:"GO:0000921"(septin ring assembly)|go:"GO:0003779"(actin binding)|refseq:NP_001271231.1|refseq:NP_061155.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:QemfgJ3tP6xprJozjv41SoVzLdU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P11717 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1048580|uniprotkb:Q7Z7G9|uniprotkb:Q96PT5|ensembl:ENSP00000349437 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mpri_human(display_long)|uniprotkb:Insulin-like growth factor 2 receptor(gene name synonym)|uniprotkb:Insulin-like growth factor II receptor(gene name synonym)|uniprotkb:M6P/IGF2 receptor(gene name synonym)|uniprotkb:300 kDa mannose 6-phosphate receptor(gene name synonym)|uniprotkb:IGF2R(gene name)|psi-mi:IGF2R(display_short)|uniprotkb:MPRI(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000867.2|go:"GO:0001965"(G-protein alpha-subunit binding)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0005010"(insulin-like growth factor-activated receptor activity)|go:"GO:0005520"(insulin-like growth factor binding)|go:"GO:0005537"(mannose binding)|go:"GO:0005641"(nuclear envelope lumen)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|ensembl:ENSG00000197081(gene)|go:"GO:0007041"(lysosomal transport)|go:"GO:0007165"(signal transduction)|ensembl:ENST00000356956(transcript)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0001889"(liver development)|go:"GO:0007283"(spermatogenesis)|go:"GO:0009791"(post-embryonic development)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0030118"(clathrin coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030140"(trans-Golgi network transport vesicle)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0031995"(insulin-like growth factor II binding)|go:"GO:0032526"(response to retinoic acid)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0044794"(positive regulation by host of viral process)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904772"(response to tetrachloromethane)|go:"GO:1905394"(retromer complex binding)|interpro:IPR000479(Cation-independent mannose-6-phosphate receptor)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR009011(Mannose-6-phosphate receptor, binding)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036943|interpro:IPR044865|mint:P11717|rcsb pdb:1E6F|rcsb pdb:1GP0|rcsb pdb:1GP3|rcsb pdb:1GQB|rcsb pdb:1JPL|rcsb pdb:1JWG|rcsb pdb:1LF8|rcsb pdb:2CNJ|rcsb pdb:2L29|rcsb pdb:2L2A|rcsb pdb:2M68|rcsb pdb:2M6T|rcsb pdb:2V5N|rcsb pdb:2V5O|rcsb pdb:2V5P|rcsb pdb:5IEI|rcsb pdb:6N5X|rcsb pdb:6N5Y|rcsb pdb:6P8I|rcsb pdb:6V02|rcsb pdb:6Z30|rcsb pdb:6Z31|rcsb pdb:6Z32|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-6811440|reactome:R-HSA-8856825|reactome:R-HSA-8856828|dip:DIP-6027N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7lkG6WR8MQ/SONiTV/8g1ZTtKTU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95487 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-81101|uniprotkb:Q0VG08|ensembl:ENSP00000265175|uniprotkb:B7ZKN4|uniprotkb:B7ZKM8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sc24b_human(display_long)|uniprotkb:SEC24B(gene name)|psi-mi:SEC24B(display_short)|uniprotkb:SEC24-related protein B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001036199.1|refseq:NP_006314.2|ensembl:ENSG00000138802(gene)|ensembl:ENST00000265175(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008270"(zinc ion binding)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0030127"(COPII vesicle coat)|go:"GO:0035909"(aorta morphogenesis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060463"(lung lobe morphogenesis)|go:"GO:0060982"(coronary artery morphogenesis)|go:"GO:0061156"(pulmonary artery morphogenesis)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0090110"(COPII-coated vesicle cargo loading)|go:"GO:0090178"(regulation of establishment of planar polarity involved in neural tube closure)|go:"GO:1901301"(regulation of cargo loading into COPII-coated vesicle)|interpro:IPR006895(Zinc finger, Sec23/Sec24-type)|interpro:IPR006896(Sec23/Sec24 trunk region)|interpro:IPR006900(Sec23/Sec24 helical region)|interpro:IPR007123(Gelsolin region)|interpro:IPR012990(Sec23/Sec24 beta-sandwich)|interpro:IPR029006|interpro:IPR036174|interpro:IPR036175|interpro:IPR036180|interpro:IPR036465|interpro:IPR041742|rcsb pdb:3EH1|go:"GO:0021747"(cochlear nucleus development)|reactome:R-HSA-204005|reactome:R-HSA-2132295|reactome:R-HSA-5694530|reactome:R-HSA-983170|reactome:R-HSA-1655829|refseq:NP_001305014.1|refseq:NP_001305015.1|refseq:NP_001287742.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ruwQ7b7xFHTKb3ckyAcWvWePc+k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P15880 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y4D1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2817289|uniprotkb:Q8N1Z8|uniprotkb:Q86U34|uniprotkb:Q8TB39|ensembl:ENSP00000378557 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:daam1_human(display_long)|uniprotkb:DAAM1(gene name)|psi-mi:DAAM1(display_short)|uniprotkb:KIAA0666(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_005267487.1|refseq:NP_055807.1|refseq:NP_001257449.1|refseq:XP_005267488.1|ensembl:ENSG00000100592(gene)|ensembl:ENST00000395125(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031514"(motile cilium)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|interpro:IPR010472(Diaphanous FH3)|interpro:IPR010473(Diaphanous GTPase-binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR014768(GTPase-binding/formin homology 3)|interpro:IPR015425(Actin-binding FH2)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042201|mint:Q9Y4D1|rcsb pdb:2J1D|rcsb pdb:2Z6E|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|interpro:IPR014767(Diaphanous autoregulatory)|dip:DIP-29641N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:nAvD3Yprt2Ayj2wLfyI15HIoyLI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95425 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-487145|uniprotkb:O60611|uniprotkb:O60612|uniprotkb:Q5VZK5|uniprotkb:Q5VZK6|uniprotkb:Q9H1R7|uniprotkb:D3DRW9|ensembl:ENSP00000348128|uniprotkb:M1J557 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:svil_human(display_long)|uniprotkb:Archvillin(gene name synonym)|uniprotkb:p205/p250(gene name synonym)|uniprotkb:SVIL(gene name)|psi-mi:SVIL(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0007519"(skeletal muscle tissue development)|refseq:NP_003165.2|refseq:NP_068506.2|ensembl:ENSG00000197321(gene)|ensembl:ENST00000355867(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|interpro:IPR007123(Gelsolin region)|interpro:IPR015628(Supervillin)|interpro:IPR029006|interpro:IPR036886|mint:O95425|rcsb pdb:2K6M|rcsb pdb:2K6N|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030496"(midbody)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0036449"(microtubule minus-end)|go:"GO:0042995"(cell projection)|go:"GO:0043034"(costamere)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR003128(Villin headpiece)|interpro:IPR007122(Gelsolin) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:5FaBAFdOX+nPJzTwEdBt8e5Keng9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14118 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1755945|uniprotkb:A8K6M7|uniprotkb:Q969J9|ensembl:ENSP00000312435|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000440705|ensembl:ENSP00000442600|ensembl:ENSP00000501140 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dag1_human(display_long)|uniprotkb:DAG1(gene name)|psi-mi:DAG1(display_short)|uniprotkb:Dystrophin-associated glycoprotein 1(gene name synonym)|uniprotkb:Dystroglycan(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001159400.2|refseq:NP_001171105.1|refseq:NP_001171106.1|refseq:NP_001171107.1|refseq:NP_001171108.1|refseq:NP_001171109.1|refseq:NP_001171110.1|refseq:NP_001171111.1|refseq:NP_001171112.1|refseq:NP_001171113.1|refseq:NP_001171114.1|refseq:NP_001171115.1|refseq:NP_004384.4|ensembl:ENSP00000312435|ensembl:ENSP00000440705|ensembl:ENSP00000438421|ensembl:ENSP00000439334|ensembl:ENSP00000440590|ensembl:ENSP00000442600|ensembl:ENSP00000501140|dip:DIP-40928N|ensembl:ENSG00000173402(gene)|ensembl:ENST00000308775(transcript)|ensembl:ENST00000515359(transcript)|ensembl:ENST00000538711(transcript)|ensembl:ENST00000539901(transcript)|ensembl:ENST00000541308(transcript)|ensembl:ENST00000545947(transcript)|ensembl:ENST00000673708(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005796"(Golgi lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007411"(axon guidance)|go:"GO:0007568"(aging)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0014894"(response to denervation involved in regulation of muscle adaptation)|go:"GO:0015631"(tubulin binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016011"(dystroglycan complex)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016203"(muscle attachment)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016340"(calcium-dependent cell-matrix adhesion)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0017166"(vinculin binding)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0021675"(nerve development)|go:"GO:0021682"(nerve maturation)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031103"(axon regeneration)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034399"(nuclear periphery)|go:"GO:0034453"(microtubule anchoring)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043236"(laminin binding)|go:"GO:0043237"(laminin-1 binding)|go:"GO:0043403"(skeletal muscle tissue regeneration)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0048714"(positive regulation of oligodendrocyte differentiation)|go:"GO:0050807"(regulation of synapse organization)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060055"(angiogenesis involved in wound healing)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060445"(branching involved in salivary gland morphogenesis)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070938"(contractile ring)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071397"(cellular response to cholesterol)|go:"GO:0071679"(commissural neuron axon guidance)|go:"GO:0071711"(basement membrane organization)|go:"GO:0098696"(regulation of neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:0098942"(retrograde trans-synaptic signaling by trans-synaptic protein complex)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR006644(Dystroglycan-type cadherin-like)|interpro:IPR008465(Dystroglycan)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR015919(Cadherin-like)|interpro:IPR027468|interpro:IPR030398|interpro:IPR041631|rcsb pdb:1EG4|rcsb pdb:2MK7|rcsb pdb:5GGP|rcsb pdb:5LLK|rcsb pdb:6JJY|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-5083628|reactome:R-HSA-5083629|reactome:R-HSA-5083633|reactome:R-HSA-5173105|reactome:R-HSA-9010553|reactome:R-HSA-9619665 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:q+98wmc5ueyzkpOCrold06eukRg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N511 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10265825|ensembl:ENSP00000292114 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tm199_human(display_long)|uniprotkb:TMEM199(gene name)|psi-mi:TMEM199(display_short)|uniprotkb:C17orf32(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_689677.1|ensembl:ENSG00000244045(gene)|ensembl:ENST00000292114(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0007042"(lysosomal lumen acidification)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016471"(vacuolar proton-transporting V-type ATPase complex)|go:"GO:0030663"(COPI-coated vesicle membrane)|go:"GO:0036295"(cellular response to increased oxygen levels)|go:"GO:0070072"(vacuolar proton-transporting V-type ATPase complex assembly)|go:"GO:1905146"(lysosomal protein catabolic process)|interpro:IPR021013|mint:Q8N511|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:rk4iRiCiPucGTNfFJWXGKL01xh09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P23229 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2436548|uniprotkb:Q9UCT1|uniprotkb:B2RMU9|uniprotkb:B4DG69|uniprotkb:B4DKB8|uniprotkb:Q08443|uniprotkb:Q0MRC7|uniprotkb:Q14646|uniprotkb:Q16508|uniprotkb:Q53RX7|uniprotkb:Q59HB7|uniprotkb:Q86VL6|uniprotkb:Q9UN03|uniprotkb:G5E9H1|uniprotkb:C4AM96|ensembl:ENSP00000406694 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ita6_human(display_long)|uniprotkb:ITGA6(gene name)|psi-mi:ITGA6(display_short)|uniprotkb:VLA-6(gene name synonym)|uniprotkb:CD49 antigen-like family member F(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000201.2|refseq:NP_001073286.1|refseq:NP_001303235.1|ensembl:ENSG00000091409(gene)|ensembl:ENST00000442250(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0010668"(ectodermal cell differentiation)|go:"GO:0010811"(positive regulation of cell-substrate adhesion)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030175"(filopodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031994"(insulin-like growth factor I binding)|go:"GO:0034676"(integrin alpha6-beta4 complex)|go:"GO:0035878"(nail development)|go:"GO:0038132"(neuregulin binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0043589"(skin morphogenesis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR000413(Integrins alpha chain)|interpro:IPR013517(FG-GAP)|interpro:IPR013519(Integrin alpha beta-propellor)|interpro:IPR013649(Integrin alpha-2)|interpro:IPR018184|interpro:IPR032695|mint:P23229|rcsb pdb:7CEB|rcsb pdb:7CEC|reactome:R-HSA-2022090|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-446107 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:YyoW/gnP6QH8w7M9UxzVxMTkpOg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P27816 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-715255|uniprotkb:Q59FT2|uniprotkb:Q68D74|uniprotkb:Q6ZUW9|uniprotkb:Q96NS9|uniprotkb:Q13082|uniprotkb:Q96A76|ensembl:ENSP00000353375|uniprotkb:Q86V26 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:map4_human(display_long)|uniprotkb:MAP4(gene name)|psi-mi:MAP4(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001127836.1|refseq:NP_002366.2|ensembl:ENSG00000047849(gene)|ensembl:ENST00000360240(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030424"(axon)|go:"GO:0031175"(neuron projection development)|go:"GO:0043005"(neuron projection)|go:"GO:0051012"(microtubule sliding)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|go:"GO:1902856"(negative regulation of non-motile cilium assembly)|interpro:IPR001084(Tubulin-binding Tau protein)|interpro:IPR027323|mint:P27816|refseq:NP_112147.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:rBf82W3kFCo+2UklK5WHO3MWjV09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35658 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1222270|uniprotkb:A6NFQ0|uniprotkb:Q15010|uniprotkb:Q3KQZ0|uniprotkb:Q5JUP7|uniprotkb:Q75R47|uniprotkb:Q86XD3|intact:EBI-2555216|ensembl:ENSP00000352400 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nu214_human(display_long)|uniprotkb:NUP214(gene name)|psi-mi:NUP214(display_short)|uniprotkb:CAIN(gene name synonym)|uniprotkb:CAN(gene name synonym)|uniprotkb:KIAA0023(gene name synonym)|uniprotkb:Nucleoporin Nup214(gene name synonym)|uniprotkb:214 kDa nucleoporin(gene name synonym)|uniprotkb:Protein CAN(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000352400|ensembl:ENST00000411637|ensembl:ENSP00000396576|refseq:NP_005076.3|refseq:NP_001305253.1|refseq:NP_001305254.1|dip:DIP-38367N|rcsb pdb:3FMP|rcsb pdb:5DIS|reactome:R-HSA-1169408|reactome:R-HSA-159227|reactome:R-HSA-159230|reactome:R-HSA-159231|reactome:R-HSA-159236|reactome:R-HSA-165054|reactome:R-HSA-168271|reactome:R-HSA-168276|reactome:R-HSA-168325|reactome:R-HSA-168333|reactome:R-HSA-170822|reactome:R-HSA-180746|reactome:R-HSA-180910|reactome:R-HSA-191859|reactome:R-HSA-3108214|reactome:R-HSA-3232142|reactome:R-HSA-3301854|reactome:R-HSA-3371453|reactome:R-HSA-4085377|reactome:R-HSA-450520|reactome:R-HSA-4551638|reactome:R-HSA-4570464|reactome:R-HSA-4615885|reactome:R-HSA-5578749|reactome:R-HSA-5619107|reactome:R-HSA-6784531|reactome:R-HSA-9609690|reactome:R-HSA-9610379|rcsb pdb:3FMO|ensembl:ENSG00000126883(gene)|ensembl:ENST00000359428(transcript)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006406"(mRNA export from nucleus)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0008139"(nuclear localization sequence binding)|go:"GO:0017056"(structural constituent of nuclear pore)|go:"GO:0046822"(regulation of nucleocytoplasmic transport)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:1990876"(cytoplasmic side of nuclear pore)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR026054|interpro:IPR041553|mint:P35658|rcsb pdb:2OIT|rcsb pdb:3FHC - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:cW7RIiR4uhQgXIaByMiW3niFtTo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O00560 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-727004|uniprotkb:O43391|ensembl:ENSP00000260130|ensembl:ENSP00000411771|uniprotkb:O00173|uniprotkb:Q14CP2|uniprotkb:B4DUH3|uniprotkb:B7ZLN2|uniprotkb:B2R5Q7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sdcb1_human(display_long)|uniprotkb:Scaffold protein Pbp1(gene name synonym)|uniprotkb:Pro-TGF-alpha cytoplasmic domain-interacting protein 18(gene name synonym)|uniprotkb:Syndecan-binding protein 1(gene name synonym)|uniprotkb:Melanoma differentiation-associated protein 9(gene name synonym)|uniprotkb:SDCBP(gene name)|psi-mi:SDCBP(display_short)|uniprotkb:MDA9(gene name synonym)|uniprotkb:SYCL(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000137575(gene)|ensembl:ENST00000260130(transcript)|ensembl:ENST00000413219(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002091"(negative regulation of receptor internalization)|go:"GO:0005109"(frizzled binding)|go:"GO:0005137"(interleukin-5 receptor binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|refseq:NP_001007068.1|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005895"(interleukin-5 receptor complex)|go:"GO:0005912"(adherens junction)|refseq:NP_001007069.1|refseq:NP_001007070.1|refseq:NP_001007071.1|refseq:NP_005616.2|go:"GO:0005925"(focal adhesion)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042043"(neurexin family protein binding)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:1903553"(positive regulation of extracellular exosome assembly)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR030528|interpro:IPR036034|go:"GO:0042802"(identical protein binding)|rcsb pdb:1N99|go:"GO:0044877"(protein-containing complex binding)|rcsb pdb:1NTE|go:"GO:0045121"(membrane raft)|rcsb pdb:1OBX|rcsb pdb:1OBY|rcsb pdb:1OBZ|go:"GO:0045202"(synapse)|go:"GO:0045545"(syndecan binding)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0050839"(cell adhesion molecule binding)|rcsb pdb:1R6J|rcsb pdb:1V1T|rcsb pdb:1W9E|rcsb pdb:1W9O|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0099054"(presynapse assembly)|go:"GO:1903543"(positive regulation of exosomal secretion)|rcsb pdb:1W9Q|rcsb pdb:1YBO|rcsb pdb:4Z33|rcsb pdb:6R9H|rcsb pdb:6RLC|reactome:R-HSA-3928664|reactome:R-HSA-447043|reactome:R-HSA-5213460|reactome:R-HSA-6798695|reactome:R-HSA-5675482|dip:DIP-42705N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ys2RNVwH0n5AKA+rBULM9Foxccg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13586 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-448878|uniprotkb:Q8N382|ensembl:ENSP00000300737|uniprotkb:E9PQJ4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stim1_human(display_long)|uniprotkb:STIM1(gene name)|psi-mi:STIM1(display_short)|uniprotkb:GOK(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003147.2|ensembl:ENSG00000167323(gene)|ensembl:ENST00000300737(transcript)|go:"GO:0002020"(protease binding)|go:"GO:0002115"(store-operated calcium entry)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005513"(detection of calcium ion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0032237"(activation of store-operated calcium channel activity)|go:"GO:0032541"(cortical endoplasmic reticulum)|go:"GO:0033017"(sarcoplasmic reticulum membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045762"(positive regulation of adenylate cyclase activity)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0070166"(enamel mineralization)|go:"GO:2001256"(regulation of store-operated calcium entry)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR030463|interpro:IPR032393|interpro:IPR037608|interpro:IPR037609|rcsb pdb:2K60|rcsb pdb:2MAJ|rcsb pdb:2MAK|rcsb pdb:3TEQ|rcsb pdb:4O9B|rcsb pdb:6YEL|reactome:R-HSA-139853|reactome:R-HSA-5578775|reactome:R-HSA-983695|refseq:NP_001264891.1|dip:DIP-31121N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GQh8kgCwqrcx7VtJdv63pW1eg/U9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75113 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-5278391|uniprotkb:A7MD49|uniprotkb:Q2YDX1|ensembl:ENSP00000262384 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:n4bp1_human(display_long)|uniprotkb:N4BP1(gene name)|psi-mi:N4BP1(display_short)|uniprotkb:KIAA0615(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_694574.3|dip:DIP-41205N|ensembl:ENSG00000102921(gene)|ensembl:ENST00000262384(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0003729"(mRNA binding)|go:"GO:0004540"(ribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0016605"(PML body)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034644"(cellular response to UV)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045088"(regulation of innate immune response)|interpro:IPR021869|rcsb pdb:6Q3V - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:DjuEYSvNvt5wy7oD2kareuxfDxM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:A0FGR8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3184170|uniprotkb:Q9ULJ2|uniprotkb:Q9NW47|uniprotkb:Q69YJ2|uniprotkb:Q6ZVU1|uniprotkb:Q6UKI4|uniprotkb:Q6ZTU0|uniprotkb:Q9BQS0|uniprotkb:A4D229 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:esyt2_human(display_long)|uniprotkb:ESYT2(gene name)|psi-mi:ESYT2(display_short)|uniprotkb:FAM62B(gene name synonym)|uniprotkb:KIAA1228(gene name synonym)|uniprotkb:Chr2Syt(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0005509"(calcium ion binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0006897"(endocytosis)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044232"(organelle membrane contact site)|go:"GO:0045296"(cadherin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0140268"(endoplasmic reticulum-plasma membrane contact site)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|go:"GO:0005789"(endoplasmic reticulum membrane)|interpro:IPR037733|interpro:IPR037749|interpro:IPR037752|interpro:IPR039010|rcsb pdb:2DMG|rcsb pdb:4NPJ|rcsb pdb:4NPK|rcsb pdb:4P42|reactome:R-HSA-1660662|refseq:NP_065779.1|mint:A0FGR8|dip:DIP-61039N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:mOkUWt8oia02xtJYM6gQz3tsav89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y4E8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1043104|uniprotkb:Q9HCA6|uniprotkb:Q9UNP0|uniprotkb:Q9Y5B5|ensembl:ENSP00000280377|uniprotkb:Q9H8G9|uniprotkb:Q08AL5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ubp15_human(display_long)|uniprotkb:Unph4(gene name synonym)|uniprotkb:USP15(gene name)|psi-mi:USP15(display_short)|uniprotkb:KIAA0529(gene name synonym)|uniprotkb:Ubiquitin-specific-processing protease 15(gene name synonym)|uniprotkb:Deubiquitinating enzyme 15(gene name synonym)|uniprotkb:Unph-2(gene name synonym)|uniprotkb:Ubiquitin thioesterase 15(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000135655(gene)|ensembl:ENST00000280377(transcript)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005160"(transforming growth factor beta receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0035520"(monoubiquitinated protein deubiquitination)|go:"GO:0035616"(histone H2B conserved C-terminal lysine deubiquitination)|go:"GO:0042802"(identical protein binding)|go:"GO:0046332"(SMAD binding)|go:"GO:0060389"(pathway-restricted SMAD protein phosphorylation)|go:"GO:0061649"(ubiquitin modification-dependent histone binding)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|go:"GO:1905035"(negative regulation of antifungal innate immune response)|go:"GO:1990167"(protein K27-linked deubiquitination)|go:"GO:1990380"(Lys48-specific deubiquitinase activity)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR006615(Ubiquitin carboxyl-terminal hydrolase, N-terminal region 1)|interpro:IPR013792(RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta)|interpro:IPR018200|interpro:IPR028135|interpro:IPR028889|interpro:IPR029071|interpro:IPR029346|interpro:IPR035927|interpro:IPR038765|mint:Q9Y4E8|rcsb pdb:1W6V|rcsb pdb:3LMN|rcsb pdb:3PPA|rcsb pdb:3PV1|rcsb pdb:3T9L|rcsb pdb:4A3O|rcsb pdb:4A3P|rcsb pdb:5JJW|rcsb pdb:6CPM|rcsb pdb:6CRN|rcsb pdb:6DJ9|rcsb pdb:6GH9|rcsb pdb:6GHA|rcsb pdb:6ML1|reactome:R-HSA-2173788|reactome:R-HSA-5689603|reactome:R-HSA-5689880|refseq:NP_006304.1|refseq:NP_001239008.1|refseq:NP_001239007.1|dip:DIP-50239N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Hjx7D3Eq+fTpjE3D3fUujJN9gW89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y371 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2623095|uniprotkb:Q9H3Z0|uniprotkb:Q9NYA9|uniprotkb:Q9NR47|uniprotkb:Q5H8U5|ensembl:ENSP00000473267|uniprotkb:B4E182 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:shlb1_human(display_long)|uniprotkb:KIAA0491(gene name synonym)|uniprotkb:Bax-interacting factor 1(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein B1(gene name synonym)|uniprotkb:CGI-61(orf name)|uniprotkb:SH3GLB1(gene name)|psi-mi:SH3GLB1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001193580.1|refseq:NP_001193581.1|refseq:NP_057093.1|go:"GO:0030496"(midbody)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032465"(regulation of cytokinesis)|go:"GO:0032801"(receptor catabolic process)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048102"(autophagic cell death)|go:"GO:0090148"(membrane fission)|go:"GO:1903527"(positive regulation of membrane tubulation)|go:"GO:1903778"(protein localization to vacuolar membrane)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|go:"GO:2000786"(positive regulation of autophagosome assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028503|interpro:IPR035695|interpro:IPR036028|mint:Q9Y371|rcsb pdb:6UP6|rcsb pdb:6UPN|ensembl:ENSG00000097033(gene)|ensembl:ENST00000370558(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006915"(apoptotic process)|go:"GO:0008289"(lipid binding)|go:"GO:0010508"(positive regulation of autophagy)|go:"GO:0016241"(regulation of macroautophagy)|refseq:NP_001193582.1|dip:DIP-41970N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:HSs455W45ciZL56fJSPOIvfhUIw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60749 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1046690|uniprotkb:O43650|uniprotkb:P82862|uniprotkb:Q53XK8|uniprotkb:Q597H6|uniprotkb:Q9BTS8|ensembl:ENSP00000368831|uniprotkb:B3KN44|uniprotkb:B4DEK4|uniprotkb:B7Z408 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snx2_human(display_long)|uniprotkb:Transformation-related gene 9 protein(gene name synonym)|uniprotkb:SNX2(gene name)|psi-mi:SNX2(display_short)|uniprotkb:TRG9(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003091.2|ensembl:ENSG00000205302(gene)|ensembl:ENST00000379516(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028653|interpro:IPR037918|mint:O60749|interpro:IPR036871|reactome:R-HSA-432722|refseq:NP_001265128.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Sb/i4ZNGqy+ixeexnp0/4uOo3jo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q01813 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-359022|uniprotkb:B3KS15|uniprotkb:Q5VSR7|uniprotkb:Q5VSR8|ensembl:ENSP00000370517 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pfkap_human(display_long)|uniprotkb:PFKP(gene name)|psi-mi:PFKP(display_short)|uniprotkb:PFKF(gene name synonym)|uniprotkb:Phosphohexokinase(gene name synonym)|uniprotkb:Phosphofructo-1-kinase isozyme C(gene name synonym)|uniprotkb:6-phosphofructokinase type C(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002618.1|ensembl:ENSG00000067057(gene)|ensembl:ENST00000381125(transcript)|go:"GO:0003872"(6-phosphofructokinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005945"(6-phosphofructokinase complex)|go:"GO:0006002"(fructose 6-phosphate metabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016208"(AMP binding)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0048029"(monosaccharide binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070095"(fructose-6-phosphate binding)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR000023(Phosphofructokinase)|interpro:IPR009161(6-phosphofructokinase, eukaryotic type)|interpro:IPR015912(Phosphofructokinase, conserved site)|interpro:IPR022953|interpro:IPR035966|interpro:IPR041914|mint:Q01813|rcsb pdb:4RH3|rcsb pdb:4U1R|rcsb pdb:4WL0|rcsb pdb:4XYJ|rcsb pdb:4XYK|rcsb pdb:4XZ2|reactome:R-HSA-70171|refseq:NP_001229268.1|dip:DIP-45850N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GNmWbFrQsTMRdVphWG+3DK3wxaA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q12913 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2264500|uniprotkb:Q9UDA9|uniprotkb:Q15255|uniprotkb:Q8NHM2|uniprotkb:Q6P4H4|ensembl:ENSP00000400010 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ptprj_human(display_long)|uniprotkb:PTPRJ(gene name)|psi-mi:PTPRJ(display_short)|uniprotkb:DEP1(gene name synonym)|uniprotkb:HPTP eta(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase receptor type J(gene name synonym)|uniprotkb:Density-enhanced phosphatase 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002834.3|refseq:NP_001091973.1|go:"GO:0070097"(delta-catenin binding)|go:"GO:1905451"(positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|interpro:IPR036116|interpro:IPR041201|mint:Q12913|rcsb pdb:2CFV|rcsb pdb:2DLE|rcsb pdb:2NZ6|reactome:R-HSA-202427|reactome:R-HSA-6798695|reactome:R-HSA-6807004|ensembl:ENSG00000149177(gene)|ensembl:ENST00000418331(transcript)|go:"GO:0001772"(immunological synapse)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005161"(platelet-derived growth factor receptor binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0035584"(calcium-mediated signaling using intracellular calcium source)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0043116"(negative regulation of vascular permeability)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060242"(contact inhibition)|go:"GO:0070062"(extracellular exosome)|go:"GO:0035579"(specific granule membrane)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0016791"(phosphatase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0006470"(protein dephosphorylation)|reactome:R-HSA-9706369 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:tGsQm2S/SSUjbnV/WwKSb4rPz/49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BRK4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-741037|ensembl:ENSP00000359240|ensembl:ENSP00000359243|uniprotkb:Q8N3I0|uniprotkb:Q96J79|uniprotkb:Q96JL2|uniprotkb:B1AL14|uniprotkb:D3DR72 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lzts2_human(display_long)|uniprotkb:Protein LAPSER1(gene name synonym)|uniprotkb:LZTS2(gene name)|psi-mi:LZTS2(display_short)|uniprotkb:KIAA1813(gene name synonym)|uniprotkb:LAPSER1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_115805.1|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0030496"(midbody)|go:"GO:0031982"(vesicle)|go:"GO:0051013"(microtubule severing)|go:"GO:0051168"(nuclear export)|go:"GO:0051255"(spindle midzone assembly)|go:"GO:0060682"(primary ureteric bud growth)|go:"GO:0072197"(ureter morphogenesis)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR028597|mint:Q9BRK4|ensembl:ENSG00000107816(gene)|ensembl:ENST00000370220(transcript)|ensembl:ENST00000370223(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0008285"(negative regulation of cell population proliferation)|refseq:XP_016872269.1|refseq:NP_001305028.1|refseq:NP_001305029.1|refseq:NP_001305030.1|refseq:XP_005270279.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:OaMJmnmfm6JniKUJeyg7fS6zRcw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y6M7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1044546|uniprotkb:O60350|uniprotkb:Q6AHZ9|uniprotkb:Q9HC88|uniprotkb:Q9UIB9|ensembl:ENSP00000295736|uniprotkb:A6NIA8|intact:EBI-11577841|uniprotkb:B2CI53|uniprotkb:B5M451|uniprotkb:B5M452|uniprotkb:B5M453|uniprotkb:B6DY52|uniprotkb:B6DY53|uniprotkb:C9JST9|uniprotkb:B5M449|uniprotkb:D3K174|uniprotkb:D3K175|intact:EBI-10982200 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:s4a7_human(display_long)|uniprotkb:Sodium bicarbonate cotransporter 2(gene name synonym)|uniprotkb:Sodium bicarbonate cotransporter 2b(gene name synonym)|uniprotkb:Solute carrier family 4 member 7(gene name synonym)|uniprotkb:SLC4A7(gene name)|psi-mi:SLC4A7(display_short)|uniprotkb:BT(gene name synonym)|uniprotkb:NBC2(gene name synonym)|uniprotkb:NBC2B(gene name synonym)|uniprotkb:NBC3(gene name synonym)|uniprotkb:SBC2(gene name synonym)|uniprotkb:SLC4A6(gene name synonym)|uniprotkb:NBCn1(gene name synonym)|uniprotkb:"Electroneutral Na/HCO(3) cotransporter"(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003606.3|ensembl:ENSG00000033867(gene)|ensembl:ENST00000295736(transcript)|go:"GO:0005452"(inorganic anion exchanger activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0008510"("sodium:bicarbonate symporter activity")|go:"GO:0015701"(bicarbonate transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0022857"(transmembrane transporter activity)|go:"GO:0032420"(stereocilium)|go:"GO:0050801"(ion homeostasis)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0055085"(transmembrane transport)|go:"GO:0060117"(auditory receptor cell development)|interpro:IPR003020(Bicarbonate transporter, eukaryotic)|interpro:IPR011531(Bicarbonate transporter, C-terminal)|interpro:IPR013769(Bicarbonate transporter, cytoplasmic)|interpro:IPR016152(Phosphotransferase/anion transporter)|reactome:R-HSA-425381|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-9013406|refseq:NP_001245308.1|refseq:NP_001245309.1|refseq:NP_001308032.1|refseq:NP_001308033.1|refseq:NP_001308034.1|refseq:NP_001308035.1|refseq:NP_001308036.1|refseq:NP_001308037.1|refseq:XP_016863017.1|refseq:XP_016863018.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:vsq90qG3qxPyZgkoyvS0MPamvOg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60503 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-6871081|ensembl:ENSP00000294016|uniprotkb:Q4ZHT9|uniprotkb:A7E2V5|uniprotkb:D3DUD1|uniprotkb:Q9UGP2|uniprotkb:Q4ZIR5|uniprotkb:Q9BWT4|uniprotkb:O60273|uniprotkb:A7E2X2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:adcy9_human(display_long)|uniprotkb:ATP pyrophosphate-lyase 9(gene name synonym)|uniprotkb:Adenylate cyclase type IX(gene name synonym)|uniprotkb:Adenylyl cyclase 9(gene name synonym)|uniprotkb:KIAA0520(gene name synonym)|uniprotkb:ADCY9(gene name)|psi-mi:ADCY9(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N reactome:R-HSA-5610787|reactome:R-HSA-9660821|reactome:R-HSA-9664323|ensembl:ENSG00000162104(gene)|ensembl:ENST00000294016(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004016"(adenylate cyclase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006171"(cAMP biosynthetic process)|go:"GO:0007165"(signal transduction)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046872"(metal ion binding)|go:"GO:0071880"(adenylate cyclase-activating adrenergic receptor signaling pathway)|interpro:IPR001054(Adenylyl cyclase class-3/4/guanylyl cyclase)|interpro:IPR018297|interpro:IPR029787|reactome:R-HSA-163359|reactome:R-HSA-163615|reactome:R-HSA-164378|reactome:R-HSA-170660|reactome:R-HSA-170670|reactome:R-HSA-418555|reactome:R-HSA-418594|reactome:R-HSA-418597|reactome:R-HSA-432040|refseq:NP_001107.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:kH9uxHYafWkdpRqXE2D0RNPtIG49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P78536 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-78188|intact:EBI-28987181|ensembl:ENSP00000309968|uniprotkb:O60226 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ada17_human(display_long)|uniprotkb:ADAM17(gene name)|psi-mi:ADAM17(display_short)|uniprotkb:CSVP(gene name synonym)|uniprotkb:TACE(gene name synonym)|uniprotkb:TNF-alpha-converting enzyme(gene name synonym)|uniprotkb:TNF-alpha convertase(gene name synonym)|uniprotkb:Snake venom-like protease(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0010820"(positive regulation of T cell chemotaxis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016485"(protein processing)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0008237"(metallopeptidase activity)|go:"GO:0042493"|go:"GO:0042987"(amyloid precursor protein catabolic process)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0033025"(regulation of mast cell apoptotic process)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0045121"(membrane raft)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045741"(positive regulation of epidermal growth factor-activated receptor activity)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0035313"(wound healing, spreading of epidermal cells)|go:"GO:0046872"(metal ion binding)|go:"GO:0048536"(spleen development)|go:"GO:0048870"(cell motility)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051272"(positive regulation of cellular component movement)|go:"GO:0071403"(cellular response to high density lipoprotein particle stimulus)|go:"GO:0120163"(negative regulation of cold-induced thermogenesis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902945"(metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:0035624"(receptor transactivation)|interpro:IPR001590(Peptidase M12B, ADAM/reprolysin)|interpro:IPR001762(Blood coagulation inhibitor, Disintegrin)|interpro:IPR002870(Peptidase M12B, propeptide)|interpro:IPR024079|interpro:IPR032029|interpro:IPR034025|interpro:IPR036436|mint:P78536|rcsb pdb:1BKC|rcsb pdb:1ZXC|rcsb pdb:2A8H|rcsb pdb:2DDF|rcsb pdb:2FV5|rcsb pdb:2FV9|rcsb pdb:2I47|rcsb pdb:2M2F|rcsb pdb:2OI0|rcsb pdb:3B92|rcsb pdb:3CKI|go:"GO:1905564"(positive regulation of vascular endothelial cell proliferation)|rcsb pdb:3E8R|rcsb pdb:3EDZ|rcsb pdb:3EWJ|rcsb pdb:3G42|rcsb pdb:3KMC|rcsb pdb:3KME|rcsb pdb:3L0T|rcsb pdb:3L0V|rcsb pdb:3LE9|rcsb pdb:3LEA|rcsb pdb:3LGP|rcsb pdb:3O64|reactome:R-HSA-1251985|reactome:R-HSA-1442490|reactome:R-HSA-177929|reactome:R-HSA-193692|reactome:R-HSA-2122948|reactome:R-HSA-2644606|reactome:R-HSA-2660826|reactome:R-HSA-2691232|reactome:R-HSA-2894862|reactome:R-HSA-5362798|ensembl:ENSG00000151694(gene)|ensembl:ENST00000310823(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002446"(neutrophil mediated immunity)|go:"GO:0002467"(germinal center formation)|go:"GO:0002690"(positive regulation of leukocyte chemotaxis)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004222"(metalloendopeptidase activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005138"(interleukin-6 receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006508"(proteolysis)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0007155"(cell adhesion)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007220"(Notch receptor processing)|go:"GO:0008233"(peptidase activity)|reactome:R-HSA-9662834|reactome:R-HSA-982772|reactome:R-HSA-75893|refseq:NP_003174.3|ensembl:ENSP00000309968|dip:DIP-31044N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9ZXiwccqzkHXJUHY1KNhH/ZGG+89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P21860 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-720706|uniprotkb:A8K6L6|uniprotkb:B4DIK7|uniprotkb:B4DV32|uniprotkb:E9PDT8|uniprotkb:Q9BUD7|ensembl:ENSP00000267101 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:erbb3_human(display_long)|uniprotkb:Tyrosine kinase-type cell surface receptor HER3(gene name synonym)|uniprotkb:ERBB3(gene name)|psi-mi:ERBB3(display_short)|uniprotkb:HER3(gene name synonym)|uniprotkb:Proto-oncogene-like protein c-ErbB-3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001005915.1|refseq:NP_001973.2|ensembl:ENSG00000065361(gene)|ensembl:ENST00000267101(transcript)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0014037"(Schwann cell differentiation)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019838"(growth factor binding)|go:"GO:0021545"(cranial nerve development)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0038131"(neuregulin receptor activity)|go:"GO:0038132"(neuregulin binding)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|dip:DIP-36441N|reactome:R-HSA-8863795|reactome:R-HSA-9664565|reactome:R-HSA-9665686|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043235"(receptor complex)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051048"(negative regulation of secretion)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR032778|interpro:IPR036941|mint:P21860|rcsb pdb:1M6B|rcsb pdb:2L9U|rcsb pdb:3KEX|rcsb pdb:3LMG|rcsb pdb:3P11|go:"GO:0042802"(identical protein binding)|rcsb pdb:4P59|rcsb pdb:4RIW|rcsb pdb:4RIX|rcsb pdb:4RIY|rcsb pdb:5CUS|rcsb pdb:5O4O|rcsb pdb:5O7P|rcsb pdb:6KBI|rcsb pdb:6OP9|rcsb pdb:7D85|reactome:R-HSA-1227986|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1257604|reactome:R-HSA-1306955|reactome:R-HSA-1358803|reactome:R-HSA-1963642|reactome:R-HSA-2219530|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|rcsb pdb:4LEO|reactome:R-HSA-8847993 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NlkxlNEYwPOsHrzcGHV0stFbKTA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P31939 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1048599|uniprotkb:Q13856|uniprotkb:Q53S28|uniprotkb:A8K202|uniprotkb:E9PBU3|ensembl:ENSP00000236959 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pur9_human(display_long)|uniprotkb:ATIC(gene name)|psi-mi:ATIC(display_short)|uniprotkb:PURH(gene name synonym)|uniprotkb:OK/SW-cl.86(orf name)|uniprotkb:AICAR transformylase/inosine monophosphate cyclohydrolase(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004035.2|ensembl:ENSG00000138363(gene)|ensembl:ENST00000236959(transcript)|go:"GO:0003360"(brainstem development)|go:"GO:0003937"(IMP cyclohydrolase activity)|go:"GO:0004643"(phosphoribosylaminoimidazolecarboxamide formyltransferase activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006139"(nucleobase-containing compound metabolic process)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009116"(nucleoside metabolic process)|go:"GO:0010035"(response to inorganic substance)|go:"GO:0016020"(membrane)|go:"GO:0021549"(cerebellum development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0031100"(animal organ regeneration)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046452"(dihydrofolate metabolic process)|go:"GO:0046654"(tetrahydrofolate biosynthetic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098761"(cellular response to interleukin-7)|interpro:IPR002695(AICARFT/IMPCHase bienzyme)|interpro:IPR011607(MGS-like)|interpro:IPR016193(Cytidine deaminase-like)|interpro:IPR024050|interpro:IPR024051|interpro:IPR036914|rcsb pdb:1P4R|rcsb pdb:1PKX|rcsb pdb:1PL0|rcsb pdb:5UY8|rcsb pdb:5UZ0|reactome:R-HSA-73817 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Xe3388w/LOBYgag9P8Gp3IGo9wU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7Z3T8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-298055|uniprotkb:O15023|uniprotkb:Q7LAU7|uniprotkb:Q86T69|uniprotkb:Q8N5L3|uniprotkb:Q8NEK3|ensembl:ENSP00000337159|ensembl:ENSP00000423663|ensembl:ENSP00000426848|uniprotkb:Q5H9U2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zfy16_human(display_long)|uniprotkb:ZFYVE16(gene name)|psi-mi:ZFYVE16(display_short)|uniprotkb:Endofin(gene name synonym)|uniprotkb:Endosome-associated FYVE domain protein(gene name synonym)|uniprotkb:KIAA0305(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000039319(gene)|ensembl:ENST00000338008(transcript)|ensembl:ENST00000505560(transcript)|ensembl:ENST00000510158(transcript)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0007165"(signal transduction)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0031901"(early endosome membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0046872"(metal ion binding)|interpro:IPR000306(Zinc finger, FYVE-type)|interpro:IPR011011(Zinc finger, FYVE/PHD-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017165(Zinc finger, FYVE-type, SARA/endofin)|interpro:IPR017455(Zinc finger, FYVE-related)|interpro:IPR022557|interpro:IPR035438|rcsb pdb:3T7L|rcsb pdb:5MK0|reactome:R-HSA-201451|refseq:NP_001271166.1|refseq:XP_011542055.1|refseq:XP_005248689.1|refseq:XP_016865580.1|refseq:XP_016865581.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:kutF+cRD+UmhN+j7tQV0vXtWau89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UMD9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2528742|uniprotkb:Q02802|uniprotkb:Q5JV36|uniprotkb:Q99018|uniprotkb:Q9NQK9|uniprotkb:Q9UC14|ensembl:ENSP00000497653 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:coha1_human(display_long)|uniprotkb:COL17A1(gene name)|psi-mi:COL17A1(display_short)|uniprotkb:BP180(gene name synonym)|uniprotkb:BPAG2(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 2(gene name synonym)|uniprotkb:180 kDa bullous pemphigoid antigen 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000485.3|ensembl:ENSG00000065618(gene)|ensembl:ENST00000648076(transcript)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005576"(extracellular region)|go:"GO:0005581"(collagen trimer)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008544"(epidermis development)|go:"GO:0030020"(extracellular matrix structural constituent conferring tensile strength)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0062023"(collagen-containing extracellular matrix)|interpro:IPR008160(Collagen triple helix repeat)|reactome:R-HSA-1442490|reactome:R-HSA-1650814|reactome:R-HSA-198933|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-8948216|go:"GO:0030198"(extracellular matrix organization) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:bLvikvLHiVVzO8dl13ka+AS2CW89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7Z6J0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-311339|intact:EBI-1374106|uniprotkb:Q05BT2|uniprotkb:Q8IW46|uniprotkb:Q9HAM2|uniprotkb:Q9P234|ensembl:ENSP00000284637 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sh3r1_human(display_long)|uniprotkb:SH3RF1(gene name)|psi-mi:SH3RF1(display_short)|uniprotkb:POSH1(gene name synonym)|uniprotkb:KIAA1494(gene name synonym)|uniprotkb:POSH(gene name synonym)|uniprotkb:RNF142(gene name synonym)|uniprotkb:SH3MD2(gene name synonym)|uniprotkb:SH3 domain-containing RING finger protein 1(gene name synonym)|uniprotkb:Plenty of SH3s(gene name synonym)|uniprotkb:SH3 multiple domains protein 2(gene name synonym)|uniprotkb:RING finger protein 142(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase SH3RF1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0001764"(neuron migration)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0030027"(lamellipodium)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043370"(regulation of CD4-positive, alpha-beta T cell differentiation)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046872"(metal ion binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051865"(protein autoubiquitination)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:2000564"(regulation of CD8-positive, alpha-beta T cell proliferation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR017907|interpro:IPR035795|interpro:IPR035816|interpro:IPR036028|mint:Q7Z6J0|reactome:R-HSA-9013424|reactome:R-HSA-983168|ensembl:ENSG00000154447(gene)|ensembl:ENST00000284637(transcript)|refseq:NP_065921.2|dip:DIP-31636N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xt8KC10AwFS6xTZVVApagbbyiJ49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N6H7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11137470|uniprotkb:Q3LIF2|uniprotkb:B4DX29|uniprotkb:Q96SX7|uniprotkb:B7Z9M7|uniprotkb:Q8N3I1|uniprotkb:D3DQQ9|ensembl:ENSP00000434442 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:arfg2_human(display_long)|uniprotkb:ARFGAP2(gene name)|psi-mi:ARFGAP2(display_short)|uniprotkb:GTPase-activating protein ZNF289(gene name synonym)|uniprotkb:ZNF289(gene name synonym)|uniprotkb:Zinc finger protein 289(gene name synonym)|uniprotkb:Nbla10535(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001229761.1|refseq:NP_115765.2|ensembl:ENSG00000149182(gene)|ensembl:ENST00000524782(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0046872"(metal ion binding)|go:"GO:0048205"(COPI coating of Golgi vesicle)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR037278|interpro:IPR038508|mint:Q8N6H7|rcsb pdb:2P57|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-9013148 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:75iMXzEM9Fi3qlCDuwZ/Y9sUOls9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q92616 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-356221|ensembl:ENSP00000300648|uniprotkb:O95001|uniprotkb:O95651|uniprotkb:Q6P2S3|uniprotkb:Q86X65|uniprotkb:Q8N5I5|uniprotkb:Q8WU80|uniprotkb:Q99736|uniprotkb:Q9UE60|uniprotkb:A8KAY1|intact:EBI-1058692 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gcn1_human(display_long)|uniprotkb:GCN1(gene name)|psi-mi:GCN1(display_short)|uniprotkb:GCN1 eIF-2-alpha kinase activator homolog(gene name synonym)|uniprotkb:GCN1-like protein 1(gene name synonym)|uniprotkb:GCN1L1(gene name synonym)|uniprotkb:General control of amino-acid synthesis 1-like protein 1(gene name synonym)|uniprotkb:KIAA0219(gene name synonym)|uniprotkb:Translational activator GCN1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000089154(gene)|ensembl:ENST00000300648(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0036003"(positive regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR021133|interpro:IPR033173|interpro:IPR034085|mint:Q92616|reactome:R-HSA-9633012|go:"GO:0005844"(polysome)|refseq:NP_006827.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NtSEW6xjvCkUyb40cnk0JdL5PcA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P22234 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-712261|ensembl:ENSP00000264221|ensembl:ENSP00000421096|uniprotkb:E9PDH9|uniprotkb:Q68CQ5|intact:EBI-21352784 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pur6_human(display_long)|uniprotkb:PAICS(gene name)|psi-mi:PAICS(display_short)|uniprotkb:ADE2(gene name synonym)|uniprotkb:AIRC(gene name synonym)|uniprotkb:PAIS(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000128050(gene)|ensembl:ENST00000264221(transcript)|ensembl:ENST00000512576(transcript)|go:"GO:0004639"(phosphoribosylaminoimidazolesuccinocarboxamide synthase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006189"('de novo' IMP biosynthetic process)|go:"GO:0009113"(purine nucleobase biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0043727"(5-amino-4-imidazole carboxylate lyase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000031("1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase")|interpro:IPR018236|interpro:IPR028923|interpro:IPR033626|mint:P22234|rcsb pdb:2H31|rcsb pdb:6YB8|go:"GO:0004638"(phosphoribosylaminoimidazole carboxylase activity)|rcsb pdb:6YB9|reactome:R-HSA-73817|refseq:NP_001072992.1|refseq:NP_001072993.1|refseq:NP_006443.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:aR4Xj14ZQrPiY8cldw5o9AvjkAo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WWM7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-948363|ensembl:ENSP00000338718|uniprotkb:O95135|uniprotkb:Q6NVJ8|uniprotkb:Q6PJW6|uniprotkb:Q8IU61|uniprotkb:Q8IU95|uniprotkb:Q8WWM3|uniprotkb:Q8WWM4|uniprotkb:Q8WWM5|uniprotkb:Q8WWM6|uniprotkb:Q99703|uniprotkb:B9EGM2|uniprotkb:E9PAR9|uniprotkb:A8K1R6|uniprotkb:Q63ZY4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:atx2l_human(display_long)|uniprotkb:Ataxin-2 domain protein(gene name synonym)|uniprotkb:Ataxin-2-related protein(gene name synonym)|uniprotkb:ATXN2L(gene name)|psi-mi:ATXN2L(display_short)|uniprotkb:A2D(gene name synonym)|uniprotkb:A2LG(gene name synonym)|uniprotkb:A2LP(gene name synonym)|uniprotkb:A2RP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000168488(gene)|ensembl:ENST00000336783(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005829"(cytosol)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010603"(regulation of cytoplasmic mRNA processing body assembly)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0034063"(stress granule assembly)|go:"GO:0045296"(cadherin binding)|interpro:IPR009604(Ataxin-2, N-terminal)|interpro:IPR009818(Ataxin-2, C-terminal)|interpro:IPR025852|mint:Q8WWM7|refseq:NP_009176.2|refseq:NP_663760.1|refseq:NP_680780.1|refseq:NP_680781.1|refseq:XP_005255123.1|refseq:NP_059867.3|refseq:NP_680782.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:t7lrS10IM/5pt+rrbqBRowZ6b+09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13873 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-527196|uniprotkb:Q16569|uniprotkb:Q13161|uniprotkb:Q4ZG08|uniprotkb:Q53SA5|uniprotkb:Q585T8|ensembl:ENSP00000363708 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:bmpr2_human(display_long)|uniprotkb:Bone morphogenetic protein receptor type II(gene name synonym)|uniprotkb:PPH1(gene name synonym)|uniprotkb:BMPR2(gene name)|psi-mi:BMPR2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N dip:DIP-5794N|refseq:NP_001195.2|ensembl:ENSG00000204217(gene)|ensembl:ENST00000374580(transcript)|go:"GO:0001568"(blood vessel development)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0001707"(mesoderm formation)|go:"GO:0001893"(maternal placenta development)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0001938"(positive regulation of endothelial cell proliferation)|go:"GO:0001946"(lymphangiogenesis)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0002063"(chondrocyte development)|go:"GO:0003085"(negative regulation of systemic arterial blood pressure)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003176"(aortic valve development)|go:"GO:0003177"(pulmonary valve development)|go:"GO:0003183"(mitral valve morphogenesis)|go:"GO:0003186"(tricuspid valve morphogenesis)|go:"GO:0003197"(endocardial cushion development)|go:"GO:0003252"(negative regulation of cell proliferation involved in heart valve morphogenesis)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005024"(transforming growth factor beta-activated receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005912"(adherens junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007178"(transmembrane receptor protein serine/threonine kinase signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010862"(positive regulation of pathway-restricted SMAD protein phosphorylation)|go:"GO:0014916"(regulation of lung blood pressure)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016362"(activin receptor activity, type II)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0019838"(growth factor binding)|go:"GO:0030166"(proteoglycan biosynthetic process)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030425"(dendrite)|go:"GO:0030501"(positive regulation of bone mineralization)|go:"GO:0030509"(BMP signaling pathway)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0030546"(signaling receptor activator activity)|go:"GO:0036122"(BMP binding)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043235"(receptor complex)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044214"(spanning component of plasma membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045778"(positive regulation of ossification)|go:"GO:0045906"(negative regulation of vasoconstriction)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0048286"(lung alveolus development)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0048842"(positive regulation of axon extension involved in axon guidance)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0060173"(limb development)|go:"GO:0060350"(endochondral bone morphogenesis)|go:"GO:0060391"(positive regulation of SMAD protein signal transduction)|go:"GO:0060412"(ventricular septum morphogenesis)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060836"(lymphatic endothelial cell differentiation)|go:"GO:0060840"(artery development)|go:"GO:0060841"(venous blood vessel development)|go:"GO:0061036"(positive regulation of cartilage development)|go:"GO:0061298"(retina vasculature development in camera-type eye)|go:"GO:0061626"(pharyngeal arch artery morphogenesis)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0014069"(postsynaptic density)|go:"GO:0072577"(endothelial cell apoptotic process)|go:"GO:0098821"(BMP receptor activity)|go:"GO:0140537"(transcription regulator activator activity)|go:"GO:1902731"(negative regulation of chondrocyte proliferation)|go:"GO:1905314"(semi-lunar valve development)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|interpro:IPR000333(Activin type II receptor)|interpro:IPR000472(TGF-beta receptor/activin receptor, type I/II)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015770(Bone morphogenic protein type II receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q13873|rcsb pdb:2HLQ|rcsb pdb:3G2F|reactome:R-HSA-201451|go:"GO:0071773"(cellular response to BMP stimulus) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZnEZsCvOyBegC07WvkGwXMz6jAw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6IBS0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-722204|uniprotkb:Q9Y3F5|ensembl:ENSP00000303908 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:twf2_human(display_long)|uniprotkb:Twinfilin-1-like protein(gene name synonym)|uniprotkb:A6-related protein(gene name synonym)|uniprotkb:Protein tyrosine kinase 9-like(gene name synonym)|uniprotkb:TWF2(gene name)|psi-mi:TWF2(display_short)|uniprotkb:PTK9L(gene name synonym)|uniprotkb:MSTP011(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_009215.1|ensembl:ENSG00000247596(gene)|ensembl:ENST00000305533(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005884"(actin filament)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0030016"(myofibril)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032420"(stereocilium)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071363"(cellular response to growth factor stimulus)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|rcsb pdb:2VAC|rcsb pdb:2W0I|reactome:R-HSA-9662360|reactome:R-HSA-9662361 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:qWz7EmcCrpyHRA+wdEsiONY16zA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BSJ8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-355956|ensembl:ENSP00000377612|uniprotkb:A0FGR7|uniprotkb:A8K2S2|uniprotkb:O94848|uniprotkb:Q6PJN4|uniprotkb:Q9H6J1|uniprotkb:Q9H6W2|uniprotkb:Q9Y416|intact:EBI-4399548 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:esyt1_human(display_long)|uniprotkb:KIAA0747(gene name synonym)|uniprotkb:MBC2(gene name synonym)|uniprotkb:ESYT1(gene name)|psi-mi:ESYT1(display_short)|uniprotkb:Membrane-bound C2 domain-containing protein(gene name synonym)|uniprotkb:FAM62A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N interpro:IPR037752|interpro:IPR039010|mint:Q9BSJ8|reactome:R-HSA-1660662|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9035034|interpro:IPR037749|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008429"(phosphatidylethanolamine binding)|go:"GO:0016020"(membrane)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0031227"(intrinsic component of endoplasmic reticulum membrane)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR031468|interpro:IPR035892|interpro:IPR037733|go:"GO:0005544"(calcium-dependent phospholipid binding)|ensembl:ENSG00000139641(gene)|ensembl:ENST00000394048(transcript)|go:"GO:0005509"(calcium ion binding)|refseq:NP_001171725.1|refseq:NP_056107.1|dip:DIP-57197N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:MYbYK3357LLH0TP1qU7CsvJenGk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TCG1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1379376|uniprotkb:B9EGC3|uniprotkb:A1L4J7|uniprotkb:Q6P4G6|uniprotkb:Q8WVP8|uniprotkb:Q96PI2|uniprotkb:Q9H9C6|uniprotkb:Q9P204|ensembl:ENSP00000295746 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cip2a_human(display_long)|uniprotkb:CIP2A(gene name)|psi-mi:CIP2A(display_short)|uniprotkb:Cancerous inhibitor of PP2A(gene name synonym)|uniprotkb:KIAA1524(gene name synonym)|uniprotkb:p90 autoantigen(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_006713780.1|refseq:NP_065941.2|refseq:XP_011511358.1|ensembl:ENSG00000163507(gene)|ensembl:ENST00000295746(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042510|rcsb pdb:5UFL - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:L9bS1Ko7hMRa/pYXVI0Gvybco8s9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P12931 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-621482|intact:EBI-28966850|ensembl:ENSP00000350941|ensembl:ENSP00000362668|ensembl:ENSP00000362680|uniprotkb:Q86VB9|uniprotkb:Q9H5A8|intact:EBI-1383910|uniprotkb:Q76P87|uniprotkb:E1P5V4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:src_human(display_long)|uniprotkb:pp60c-src(gene name synonym)|uniprotkb:SRC(gene name)|psi-mi:SRC(display_short)|uniprotkb:SRC1(gene name synonym)|uniprotkb:Proto-oncogene c-Src(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000350941|ensembl:ENST00000373558|ensembl:ENSP00000362659|ensembl:ENSP00000362668|ensembl:ENSP00000362680|go:"GO:0005925"(focal adhesion)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0009615"(response to virus)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010632"(regulation of epithelial cell migration)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0010907"(positive regulation of glucose metabolic process)|go:"GO:0010954"(positive regulation of protein processing)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016236"(macroautophagy)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0020037"(heme binding)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030168"(platelet activation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0030900"(forebrain development)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031295"(T cell costimulation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031648"(protein destabilization)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0033146"(regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0033625"(positive regulation of integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035306"(positive regulation of dephosphorylation)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036035"(osteoclast development)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0038096"(Fc-gamma receptor signaling pathway involved in phagocytosis)|go:"GO:0038128"(ERBB2 signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042476"(odontogenesis)|go:"GO:0042493"|go:"GO:0043005"(neuron projection)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0043274"(phospholipase binding)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043552"(positive regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045056"(transcytosis)|go:"GO:0045087"(innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045124"(regulation of bone resorption)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0034332"(adherens junction organization)|ensembl:ENSG00000197122(gene)|ensembl:ENST00000358208(transcript)|ensembl:ENST00000373567(transcript)|ensembl:ENST00000373578(transcript)|go:"GO:0001545"(primary ovarian follicle growth)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0002102"(podosome)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0002862"(negative regulation of inflammatory response to antigenic stimulus)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005764"(lysosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0070700"(BMP receptor binding)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071253"(connexin binding)|go:"GO:0071375"(cellular response to peptide hormone stimulus)|go:"GO:0071393"(cellular response to progesterone stimulus)|go:"GO:0071398"(cellular response to fatty acid)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048011"(neurotrophin TRK receptor signaling pathway)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048477"(oogenesis)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050847"(progesterone receptor signaling pathway)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051057"(positive regulation of small GTPase mediated signal transduction)|go:"GO:0051117"(ATPase binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051222"(positive regulation of protein transport)|go:"GO:0051385"(response to mineralocorticoid)|go:"GO:0051602"(response to electrical stimulus)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051902"(negative regulation of mitochondrial depolarization)|go:"GO:0051974"(negative regulation of telomerase activity)|go:"GO:0060065"(uterus development)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0060491"(regulation of cell projection assembly)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0086098"(angiotensin-activated signaling pathway involved in heart process)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098962"(regulation of postsynaptic neurotransmitter receptor activity)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099091"(postsynaptic specialization, intracellular component)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1903997"(positive regulation of non-membrane spanning protein tyrosine kinase activity)|go:"GO:2000386"(positive regulation of ovarian follicle development)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:2000573"(positive regulation of DNA biosynthetic process)|go:"GO:2000588"(positive regulation of platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:2000641"(regulation of early endosome to late endosome transport)|go:"GO:2000811"(negative regulation of anoikis)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001243"(negative regulation of intrinsic apoptotic signaling pathway)|go:"GO:2001286"(regulation of caveolin-mediated endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR000980(SH2 motif)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001452(Src homology-3)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR036028|interpro:IPR036860|mint:P12931|rcsb pdb:1A07|rcsb pdb:1A08|rcsb pdb:1A09|rcsb pdb:1A1A|rcsb pdb:1A1B|rcsb pdb:1A1C|rcsb pdb:1A1E|rcsb pdb:1FMK|rcsb pdb:1HCS|rcsb pdb:1HCT|rcsb pdb:1KSW|rcsb pdb:1O41|rcsb pdb:1O42|rcsb pdb:1O43|rcsb pdb:1O44|rcsb pdb:1O45|rcsb pdb:1O46|rcsb pdb:1O47|rcsb pdb:1O49|rcsb pdb:1O4A|rcsb pdb:1O4B|rcsb pdb:1O4C|rcsb pdb:1O4D|rcsb pdb:1O4E|rcsb pdb:1O4F|rcsb pdb:1O4G|rcsb pdb:1O4H|rcsb pdb:1O4I|rcsb pdb:1O4J|rcsb pdb:1O4K|rcsb pdb:1O4L|rcsb pdb:1O4M|rcsb pdb:1O4N|rcsb pdb:1O4O|rcsb pdb:1O4P|rcsb pdb:1O4Q|rcsb pdb:1O4R|rcsb pdb:1O48|rcsb pdb:1Y57|rcsb pdb:1YI6|rcsb pdb:1YOJ|rcsb pdb:1YOL|rcsb pdb:1YOM|rcsb pdb:2BDF|rcsb pdb:2BDJ|rcsb pdb:2H8H|rcsb pdb:2SRC|rcsb pdb:3VRO|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:4F59|rcsb pdb:4F5A|rcsb pdb:4F5B|rcsb pdb:4HXJ|rcsb pdb:4K11|rcsb pdb:4MXO|rcsb pdb:4MXX|rcsb pdb:4MXY|rcsb pdb:4MXZ|rcsb pdb:6ATE|rcsb pdb:6C4S|rcsb pdb:6E6E|rcsb pdb:6EHJ|reactome:R-HSA-1227986|reactome:R-HSA-1251985|reactome:R-HSA-1253288|reactome:R-HSA-1257604|reactome:R-HSA-1295596|reactome:R-HSA-1433557|reactome:R-HSA-1433559|reactome:R-HSA-171007|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-186763|reactome:R-HSA-191650|reactome:R-HSA-2029481|reactome:R-HSA-210990|reactome:R-HSA-2219530|reactome:R-HSA-2682334|reactome:R-HSA-354192|reactome:R-HSA-354194|rcsb pdb:1SHD|reactome:R-HSA-372708|reactome:R-HSA-375165|reactome:R-HSA-389356|reactome:R-HSA-391160|reactome:R-HSA-3928662|reactome:R-HSA-3928663|reactome:R-HSA-3928664|reactome:R-HSA-3928665|reactome:R-HSA-418555|reactome:R-HSA-418592|reactome:R-HSA-418594|reactome:R-HSA-418885|reactome:R-HSA-418886|reactome:R-HSA-428542|reactome:R-HSA-430116|reactome:R-HSA-437239|reactome:R-HSA-4420097|reactome:R-HSA-456926|reactome:R-HSA-5218921|reactome:R-HSA-5607764|reactome:R-HSA-5663220|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-389513|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-6811558|reactome:R-HSA-9664422|reactome:R-HSA-9670439|reactome:R-HSA-69231|reactome:R-HSA-8853659|reactome:R-HSA-8874081|reactome:R-HSA-8876493|reactome:R-HSA-8934593|reactome:R-HSA-8934903|reactome:R-HSA-8940973|reactome:R-HSA-8941858|reactome:R-HSA-9009391|reactome:R-HSA-9032500|reactome:R-HSA-9603381|reactome:R-HSA-9620244|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9664323|refseq:NP_005408.1|refseq:NP_938033.1|refseq:XP_011527315.1|refseq:XP_016883513.1|refseq:XP_016883514.1|refseq:XP_016883515.1|refseq:XP_016883516.1|dip:DIP-1059N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:8INdbX0tGHvmmiPKAw60bvecJAg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96KG9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-949287|intact:EBI-28972634|ensembl:ENSP00000270176|uniprotkb:A6NJF1|uniprotkb:Q96G50|uniprotkb:Q96KG8|uniprotkb:Q96KH1|uniprotkb:Q9HAW5|uniprotkb:Q9HBL3|uniprotkb:Q9NR53 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:scyl1_human(display_long)|uniprotkb:SCY1-like protein 1(gene name synonym)|uniprotkb:Teratoma-associated tyrosine kinase(gene name synonym)|uniprotkb:Telomerase transcriptional element-interacting factor(gene name synonym)|uniprotkb:Telomerase regulation-associated protein(gene name synonym)|uniprotkb:SCYL1(gene name)|psi-mi:SCYL1(display_short)|uniprotkb:Coated vesicle-associated kinase of 90 kDa(gene name synonym)|uniprotkb:CVAK90(gene name synonym)|uniprotkb:GKLP(gene name synonym)|uniprotkb:NTKL(gene name synonym)|uniprotkb:TAPK(gene name synonym)|uniprotkb:TEIF(gene name synonym)|uniprotkb:TRAP(gene name synonym)|uniprotkb:HT019(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000142186(gene)|ensembl:ENST00000270176(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006954"(inflammatory response)|go:"GO:0016020"(membrane)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0048666"(neuron development)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|refseq:NP_001041683.1|refseq:NP_065731.3|ensembl:ENSP00000270176|ensembl:ENST00000420247|ensembl:ENSP00000408192|ensembl:ENST00000533862|ensembl:ENSP00000437254|refseq:XP_005274177.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:qHL7to7M3sjqepd3yuU1uo4Mhy49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TDY2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1047793|uniprotkb:Q92601|uniprotkb:Q8WVU9|uniprotkb:Q86YR4|ensembl:ENSP00000025008 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rbcc1_human(display_long)|uniprotkb:RB1CC1(gene name)|psi-mi:RB1CC1(display_short)|uniprotkb:KIAA0203(gene name synonym)|uniprotkb:RBICC(gene name synonym)|uniprotkb:FAK family kinase-interacting protein of 200 kDa(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001077086.1|refseq:NP_055596.3|refseq:XP_011515945.1|refseq:XP_016869596.1|ensembl:ENSG00000023287(gene)|ensembl:ENST00000025008(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000407"(phagophore assembly site)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001889"(liver development)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005764"(lysosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0007049"(cell cycle)|go:"GO:0007507"(heart development)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030242"(autophagy of peroxisome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0034045"(phagophore assembly site membrane)|go:"GO:0034727"(piecemeal microautophagy of the nucleus)|go:"GO:0045793"(positive regulation of cell size)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061709"(reticulophagy)|go:"GO:0061723"(glycophagy)|go:"GO:1990316"(Atg1/ULK1 kinase complex)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR019460|interpro:IPR040040|mint:Q8TDY2|rcsb pdb:6DCE|rcsb pdb:6GMA|rcsb pdb:7CZG|rcsb pdb:7CZM|rcsb pdb:7D0E|reactome:R-HSA-1632852|dip:DIP-45969N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3qWsqPCX1PTO00mfVMJejr7QLwU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P60880 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-524785|uniprotkb:P13795|uniprotkb:P36974|uniprotkb:P70557|uniprotkb:P70558|uniprotkb:Q8IXK3|uniprotkb:Q96FM2|uniprotkb:Q9BR45|uniprotkb:B2RAU4|uniprotkb:Q53EM2|uniprotkb:Q5U0B5|uniprotkb:D3DW16|uniprotkb:D3DW17|ensembl:ENSP00000254976 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snp25_human(display_long)|uniprotkb:Synaptosomal-associated 25 kDa protein(gene name synonym)|uniprotkb:Super protein(gene name synonym)|uniprotkb:SNAP25(gene name)|psi-mi:SNAP25(display_short)|uniprotkb:SNAP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_005260865.1|refseq:XP_016883510.1|refseq:NP_003072.2|refseq:NP_570824.1|ensembl:ENSG00000132639(gene)|ensembl:ENST00000254976(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005249"(voltage-gated potassium channel activity)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007626"(locomotory behavior)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008306"(associative learning)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016079"(synaptic vesicle exocytosis)|go:"GO:0016081"(synaptic vesicle docking)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0017075"(syntaxin-1 binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030426"(growth cone)|go:"GO:0031201"(SNARE complex)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070032"(synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098794"(postsynapse)|go:"GO:0098967"(exocytic insertion of neurotransmitter receptor to postsynaptic membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099590"(neurotransmitter receptor internalization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|interpro:IPR039077|mint:P60880|rcsb pdb:1KIL|rcsb pdb:1XTG|rcsb pdb:2N1T|rcsb pdb:3DDA|rcsb pdb:3DDB|rcsb pdb:3RK2|rcsb pdb:3RK3|rcsb pdb:3RL0|rcsb pdb:3ZUR|rcsb pdb:5W7I|rcsb pdb:5W7J|rcsb pdb:6JLH|reactome:R-HSA-181429|reactome:R-HSA-181430|reactome:R-HSA-210500|reactome:R-HSA-212676|reactome:R-HSA-264642|reactome:R-HSA-422356|reactome:R-HSA-449836|reactome:R-HSA-5250968|reactome:R-HSA-5250971|reactome:R-HSA-5250992|reactome:R-HSA-6798695|reactome:R-HSA-888590|reactome:R-HSA-9662360|refseq:XP_016883511.1|refseq:NP_001309831.1|refseq:NP_001309832.1|refseq:NP_001309833.1|refseq:NP_001309834.1|refseq:NP_001309835.1|refseq:NP_001309836.1|refseq:NP_001309837.1|refseq:NP_001309838.1|refseq:NP_001309839.1|dip:DIP-34554N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/Z7IJEKvHKJbZS4f4oDDyluztHs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T2T1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2514004|ensembl:ENSP00000337907|ensembl:ENSP00000364871|ensembl:ENSP00000364884|ensembl:ENSP00000507917|uniprotkb:B2RCC9|uniprotkb:Q5T2T0|uniprotkb:B5MDZ3|uniprotkb:Q8IY28|uniprotkb:B4DWL9|uniprotkb:D3DRW3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mpp7_human(display_long)|uniprotkb:MPP7(gene name)|psi-mi:MPP7(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000150054(gene)|ensembl:ENST00000337532(transcript)|ensembl:ENST00000375719(transcript)|ensembl:ENST00000375732(transcript)|ensembl:ENST00000683449(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071896"(protein localization to adherens junction)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR014775(L27, C-terminal)|interpro:IPR020590|interpro:IPR027417|interpro:IPR035599|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q5T2T1|rcsb pdb:3LRA|rcsb pdb:3O46|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|reactome:R-HSA-9013409|reactome:R-HSA-9013423|refseq:XP_011517639.1|refseq:NP_001305099.1|refseq:NP_775767.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:QYVCkD5zsnTsCd7YsYsbQY8L7fU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13112 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1052944|uniprotkb:Q99548|ensembl:ENSP00000315700 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:caf1b_human(display_long)|uniprotkb:Chromatin assembly factor I p60 subunit(gene name synonym)|uniprotkb:M-phase phosphoprotein 7(gene name synonym)|uniprotkb:CHAF1B(gene name)|psi-mi:CHAF1B(display_short)|uniprotkb:CAF1A(gene name synonym)|uniprotkb:CAF1P60(gene name synonym)|uniprotkb:MPHOSPH7(gene name synonym)|uniprotkb:MPP7(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005432.1|dip:DIP-29243N|ensembl:ENSG00000159259(gene)|ensembl:ENST00000314103(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006281"(DNA repair)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006335"(DNA replication-dependent chromatin assembly)|go:"GO:0007049"(cell cycle)|go:"GO:0031497"(chromatin assembly)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033186"(CAF-1 complex)|go:"GO:0042393"(histone binding)|go:"GO:0051082"(unfolded protein binding)|interpro:IPR001632(G-protein, beta subunit)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR029129|interpro:IPR036322|mint:Q13112|refseq:XP_016883966.1|refseq:XP_016883967.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:VVbW9mpUGYMRPxvlEk9FERHIsJs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q70EL4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2512700|ensembl:ENSP00000285199|uniprotkb:Q8N2C5|uniprotkb:A6NDT9|uniprotkb:Q96DQ6|uniprotkb:B7ZLT9|uniprotkb:B7ZVX5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ubp43_human(display_long)|uniprotkb:USP43(gene name)|psi-mi:USP43(display_short)|uniprotkb:Ubiquitin-specific-processing protease 43(gene name synonym)|uniprotkb:Deubiquitinating enzyme 43(gene name synonym)|uniprotkb:Ubiquitin thioesterase 43(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000154914(gene)|ensembl:ENST00000285199(transcript)|go:"GO:0004843"(thiol-dependent deubiquitinase)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0016579"(protein deubiquitination)|go:"GO:0019785"(ISG15-specific protease activity)|go:"GO:0019985"(translesion synthesis)|interpro:IPR001394(Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)|interpro:IPR018200|interpro:IPR028889|interpro:IPR038765|mint:Q70EL4|reactome:R-HSA-5656169|refseq:XP_011521944.1|refseq:NP_694942.3|refseq:NP_001254505.1|refseq:XP_016879649.1|refseq:XP_016879650.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+SANKIEEdBufqJU5XmrGbqXjnu09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9P0L0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1059156|uniprotkb:Q9UBZ2|uniprotkb:O75453|uniprotkb:Q5U0E7|intact:EBI-2556404|uniprotkb:A6NDZ0|intact:EBI-2512000|uniprotkb:D3DUI3|ensembl:ENSP00000382880 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vapa_human(display_long)|uniprotkb:VAPA(gene name)|psi-mi:VAPA(display_short)|uniprotkb:VAP33(gene name synonym)|uniprotkb:33 kDa VAMP-associated protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003565.4|refseq:NP_919415.2|dip:DIP-41135N|go:"GO:0031982"(vesicle)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0061025"(membrane fusion)|go:"GO:0070972"(protein localization to endoplasmic reticulum)|go:"GO:0090114"(COPII-coated vesicle budding)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:Q9P0L0|rcsb pdb:2RR3|rcsb pdb:6TQR|reactome:R-HSA-1660661|reactome:R-HSA-6798695|reactome:R-HSA-9609523|ensembl:ENSG00000101558(gene)|ensembl:ENST00000400000(transcript)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0031965"(nuclear membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0008017"(microtubule binding)|go:"GO:0008219"(cell death)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:h8NG5Ak0n6b/iq2yKYMsLsJKpos9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9HB19 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4401947 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkha2_human(display_long)|uniprotkb:PLEKHA2(gene name)|psi-mi:PLEKHA2(display_short)|uniprotkb:TAPP2(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_067636.1|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR001849(Pleckstrin-like)|reactome:R-HSA-1660499|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0001968"(fibronectin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:gaDNQEdJ1GwHMQcxHJxP+GIaaXE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O76021 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-358028|uniprotkb:Q2M1T7|uniprotkb:Q6PL22|uniprotkb:Q8IWS7|uniprotkb:Q8WUZ1|uniprotkb:Q9HDA9|uniprotkb:Q9Y3Z9|uniprotkb:B4DJ58|uniprotkb:D3DUG7|ensembl:ENSP00000460871 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl1d1_human(display_long)|uniprotkb:RSL1D1(gene name)|psi-mi:RSL1D1(display_short)|uniprotkb:CSIG(gene name synonym)|uniprotkb:PBK1(gene name synonym)|uniprotkb:CATX11(gene name synonym)|uniprotkb:L12(orf name)|uniprotkb:Cellular senescence-inhibited gene protein(gene name synonym)|uniprotkb:Protein PBK1(gene name synonym)|uniprotkb:CATX-11(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_056474.2|ensembl:ENSG00000171490(gene)|ensembl:ENST00000571133(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0016020"(membrane)|go:"GO:0030686"(90S preribosome)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:2000772"(regulation of cellular senescence)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023674|interpro:IPR028364|mint:O76021 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/mAkpodrvvZA6mz3M8VwHDEJzKo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q04721 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2652733|uniprotkb:Q5T3X7|uniprotkb:Q99734|uniprotkb:Q9H240|ensembl:ENSP00000256646 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:notc2_human(display_long)|uniprotkb:NOTCH2(gene name)|psi-mi:NOTCH2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001186930.1|refseq:NP_077719.2|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042060"(wound healing)|go:"GO:0042742"(defense response to bacterium)|go:"GO:0043011"(myeloid dendritic cell differentiation)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0045672"(positive regulation of osteoclast differentiation)|go:"GO:0045967"(negative regulation of growth rate)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0046849"(bone remodeling)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060413"(atrial septum morphogenesis)|go:"GO:0060674"(placenta blood vessel development)|go:"GO:0061073"(ciliary body morphogenesis)|go:"GO:0061314"(Notch signaling involved in heart development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070986"(left/right axis specification)|go:"GO:0072014"(proximal tubule development)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:0072104"(glomerular capillary formation)|go:"GO:0072574"(hepatocyte proliferation)|go:"GO:1990705"(cholangiocyte proliferation)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2001204"(regulation of osteoclast development)|interpro:IPR000152(Aspartic acid and asparagine hydroxylation site)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR000800(Notch region)|interpro:IPR001881(EGF-like calcium-binding)|interpro:IPR002110(Ankyrin)|interpro:IPR008297(Notch)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0035622"(intrahepatic bile duct development)|interpro:IPR011656(Notch, NODP region)|interpro:IPR013032(EGF-like region, conserved site)|interpro:IPR018097|interpro:IPR020683|interpro:IPR022336|interpro:IPR010660(Notch, NOD region)|interpro:IPR024600|interpro:IPR035993|interpro:IPR036770|mint:Q04721|rcsb pdb:2OO4|rcsb pdb:5MWB|reactome:R-HSA-1912399|reactome:R-HSA-1912408|reactome:R-HSA-1912420|reactome:R-HSA-2197563|reactome:R-HSA-2979096|reactome:R-HSA-350054|reactome:R-HSA-5083630|reactome:R-HSA-9013695|ensembl:ENSG00000134250(gene)|ensembl:ENST00000256646(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001709"(cell fate determination)|go:"GO:0001947"(heart looping)|go:"GO:0002011"(morphogenesis of an epithelial sheet)|go:"GO:0002315"(marginal zone B cell differentiation)|go:"GO:0002437"(inflammatory response to antigenic stimulus)|go:"GO:0003162"(atrioventricular node development)|go:"GO:0003184"(pulmonary valve morphogenesis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0006959"(humoral immune response)|go:"GO:0007219"(Notch signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007399"(nervous system development)|go:"GO:0007411"(axon guidance)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010838"(positive regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030326"(embryonic limb morphogenesis)|go:"GO:0030513"(positive regulation of BMP signaling pathway)|go:"GO:0035264"(multicellular organism growth) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:aXdQSGMwNJ7K0tA2kc3rRFysbIc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P51617 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-358664|uniprotkb:Q7Z5V4|uniprotkb:Q96RL2|intact:EBI-28987029|ensembl:ENSP00000358997|uniprotkb:D3DWW4|uniprotkb:D3DWW3|uniprotkb:Q96C06 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:irak1_human(display_long)|uniprotkb:IRAK1(gene name)|psi-mi:IRAK1(display_short)|uniprotkb:IRAK(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032481"(positive regulation of type I interferon production)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034134"(toll-like receptor 2 signaling pathway)|go:"GO:0034142"(toll-like receptor 4 signaling pathway)|go:"GO:0034162"(toll-like receptor 9 signaling pathway)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0070498"(interleukin-1-mediated signaling pathway)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1904996"(positive regulation of leukocyte adhesion to vascular endothelial cell)|interpro:IPR000488(Death)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011029(DEATH-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR035533|interpro:IPR035536|mint:P51617|rcsb pdb:6BFN|ensembl:ENSG00000184216(gene)|ensembl:ENST00000369980(transcript)|go:"GO:0001959"(regulation of cytokine-mediated signaling pathway)|go:"GO:0002224"(toll-like receptor signaling pathway)|go:"GO:0002755"(MyD88-dependent toll-like receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004704"(NF-kappaB-inducing kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007250"(activation of NF-kappaB-inducing kinase activity)|go:"GO:0007254"(JNK cascade)|go:"GO:0007568"(aging)|go:"GO:0010008"(endosome membrane)|go:"GO:0016301"(kinase activity)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031663"(lipopolysaccharide-mediated signaling pathway)|refseq:NP_001020413.1|refseq:NP_001020414.1|refseq:NP_001560.2|reactome:R-HSA-1257604|reactome:R-HSA-166058|reactome:R-HSA-168638|reactome:R-HSA-209543|reactome:R-HSA-209560|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-6811558|reactome:R-HSA-8986944|reactome:R-HSA-9020702|reactome:R-HSA-937039|reactome:R-HSA-975110|reactome:R-HSA-975138|reactome:R-HSA-975144|reactome:R-HSA-975155|reactome:R-HSA-975871|ensembl:ENST00000369974|ensembl:ENSP00000358997|ensembl:ENST00000393687|ensembl:ENSP00000377291|ensembl:ENSP00000358991|dip:DIP-397N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:q+oAzeVuuQvO24HkoHx6PKK7XUY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7KZF4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1044112|uniprotkb:Q13122|ensembl:ENSP00000346762|uniprotkb:Q96AG0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snd1_human(display_long)|uniprotkb:100 kDa coactivator(gene name synonym)|uniprotkb:EBNA2 coactivator p100(gene name synonym)|uniprotkb:Tudor domain-containing protein 11(gene name synonym)|uniprotkb:SND1(gene name)|psi-mi:SND1(display_short)|uniprotkb:p100 co-activator(gene name synonym)|uniprotkb:TDRD11(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055205.2|ensembl:ENSG00000197157(gene)|ensembl:ENST00000354725(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004519"(endonuclease activity)|go:"GO:0004521"(endoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006401"(RNA catabolic process)|go:"GO:0010564"(regulation of cell cycle process)|go:"GO:0010587"(miRNA catabolic process)|go:"GO:0016020"(membrane)|go:"GO:0016442"(RISC complex)|go:"GO:0031047"(gene silencing by RNA)|go:"GO:0042470"(melanosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097433"(dense body)|go:"GO:1905172"(RISC complex binding)|interpro:IPR002071(Thermonuclease active site)|interpro:IPR002999(Tudor)|interpro:IPR016071("Staphylococcal nuclease (SNase-like), OB-fold")|interpro:IPR016685(RNA-induced silencing complex, nuclease component Tudor-SN)|interpro:IPR035437|mint:Q7KZF4|rcsb pdb:2E6N|rcsb pdb:2HQE|rcsb pdb:2HQX|rcsb pdb:2O4X|rcsb pdb:3BDL|rcsb pdb:3OMC|rcsb pdb:3OMG|rcsb pdb:4QMG|rcsb pdb:5M9O|reactome:R-HSA-6802952|dip:DIP-29613N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:I9JNlRfASs5dwk0JZQ+F+GsW94g9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q2M2I8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1383433|uniprotkb:Q4ZFZ3|uniprotkb:Q53RX6|uniprotkb:Q9UPV4|ensembl:ENSP00000386456 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:aak1_human(display_long)|uniprotkb:AAK1(gene name)|psi-mi:AAK1(display_short)|uniprotkb:KIAA1048(gene name synonym)|uniprotkb:Adaptor-associated kinase 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055726.3|ensembl:ENSG00000115977(gene)|ensembl:ENST00000409085(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005112"(Notch binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006897"(endocytosis)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035612"(AP-2 adaptor complex binding)|go:"GO:0043195"(terminal bouton)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0050821"(protein stabilization)|go:"GO:0061024"(membrane organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000369"(regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:4WSQ|rcsb pdb:5L4Q|rcsb pdb:5TE0|reactome:R-HSA-8856825|reactome:R-HSA-8856828 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RorQ1U6bmiSsmR0TWsyvrF+rkL89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95490 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2865302|uniprotkb:Q9UKY5|uniprotkb:B1ALT9|uniprotkb:B1ALU0|uniprotkb:Q9UKY6|uniprotkb:B1ALT8|uniprotkb:O94882|uniprotkb:Q5VX76|uniprotkb:A5XEI2|uniprotkb:B1ALU2|uniprotkb:B1ALU4|uniprotkb:B1ALU5|uniprotkb:B1ALU6|intact:EBI-28986872|ensembl:ENSP00000359752|ensembl:ENSP00000359763 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:agrl2_human(display_long)|uniprotkb:ADGRL2(gene name)|psi-mi:ADGRL2(display_short)|uniprotkb:Calcium-independent alpha-latrotoxin receptor 2(gene name synonym)|uniprotkb:KIAA0786(gene name synonym)|uniprotkb:LEC1(gene name synonym)|uniprotkb:LPHH1(gene name synonym)|uniprotkb:LPHN2(gene name synonym)|uniprotkb:Latrophilin homolog 1(gene name synonym)|uniprotkb:Latrophilin-2(gene name synonym)|uniprotkb:Lectomedin-1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001284633.1|refseq:NP_001284634.1|refseq:NP_001284635.1|refseq:NP_036434.1|ensembl:ENST00000319517|ensembl:ENSP00000322270|ensembl:ENST00000359929|ensembl:ENSP00000353006|ensembl:ENST00000370713|ensembl:ENSP00000359748|ensembl:ENST00000370715|ensembl:ENSP00000359750|ensembl:ENSP00000359752|ensembl:ENST00000370723|ensembl:ENSP00000359758|ensembl:ENST00000370725|ensembl:ENSP00000359760|ensembl:ENSP00000359763|ensembl:ENST00000370730|ensembl:ENSP00000359765|ensembl:ENST00000674393|ensembl:ENSP00000501431|ensembl:ENST00000674419|ensembl:ENSP00000501462|refseq:XP_005270723.1|refseq:NP_001317574.1|refseq:XP_016856276.1|ensembl:ENSG00000117114(gene)|ensembl:ENST00000370717(transcript)|ensembl:ENST00000370728(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007189"(adenylate cyclase-activating G protein-coupled receptor signaling pathway)|go:"GO:0007420"(brain development)|go:"GO:0009617"(response to bacterium)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016524"(latrotoxin receptor activity)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0043005"(neuron projection)|go:"GO:0050808"(synapse organization)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099055"(integral component of postsynaptic membrane)|interpro:IPR000203(GPS)|interpro:IPR000832(GPCR, family 2, secretin-like)|interpro:IPR000922(D-galactoside/L-rhamnose binding SUEL lectin)|interpro:IPR001879(GPCR, family 2, extracellular region)|interpro:IPR003112(Olfactomedin-like)|interpro:IPR003334(GPCR, family 2, latrophilin, C-terminal)|interpro:IPR003924(GPCR, family 2, latrophilin)|interpro:IPR017981|interpro:IPR017983|interpro:IPR031240|interpro:IPR032471|interpro:IPR036445|interpro:IPR043159 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WkTs1zEQmAT82KxUL2+V7KG74UQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P33176 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-355878|uniprotkb:A0AVB2|uniprotkb:Q5VZ85|ensembl:ENSP00000307078 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:kinh_human(display_long)|uniprotkb:KIF5B(gene name)|psi-mi:KIF5B(display_short)|uniprotkb:KNS(gene name synonym)|uniprotkb:KNS1(gene name synonym)|uniprotkb:Ubiquitous kinesin heavy chain(gene name synonym)|uniprotkb:Conventional kinesin heavy chain(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004512.1|ensembl:ENSG00000170759(gene)|ensembl:ENST00000302418(transcript)|go:"GO:0003777"(microtubule motor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005874"(microtubule)|go:"GO:0007018"(microtubule-based movement)|go:"GO:0007028"(cytoplasm organization)|go:"GO:0007411"(axon guidance)|go:"GO:0008017"(microtubule binding)|go:"GO:0008432"(JUN kinase binding)|go:"GO:0008574"(plus-end-directed microtubule motor activity)|go:"GO:0016020"(membrane)|go:"GO:0021766"(hippocampus development)|go:"GO:0030705"(cytoskeleton-dependent intracellular transport)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031982"(vesicle)|go:"GO:0032230"(positive regulation of synaptic transmission, GABAergic)|go:"GO:0032418"(lysosome localization)|go:"GO:0032839"(dendrite cytoplasm)|go:"GO:0034451"(centriolar satellite)|go:"GO:0035253"(ciliary rootlet)|go:"GO:0035617"(stress granule disassembly)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042802"(identical protein binding)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0047496"(vesicle transport along microtubule)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0051642"(centrosome localization)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0072383"(plus-end-directed vesicle transport along microtubule)|go:"GO:0090316"(positive regulation of intracellular protein transport)|go:"GO:0098971"(anterograde dendritic transport of neurotransmitter receptor complex)|go:"GO:0099609"(microtubule lateral binding)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1905152"(positive regulation of voltage-gated sodium channel activity)|go:"GO:1990048"(anterograde neuronal dense core vesicle transport)|go:"GO:1990049"(retrograde neuronal dense core vesicle transport)|interpro:IPR001752(Kinesin, motor region)|interpro:IPR019821|interpro:IPR027417|interpro:IPR027640|interpro:IPR036961|mint:P33176|rcsb pdb:1BG2|rcsb pdb:1MKJ|rcsb pdb:2P4N|rcsb pdb:3J8X|rcsb pdb:3J8Y|rcsb pdb:4HNA|rcsb pdb:4LNU|rcsb pdb:5LT0|rcsb pdb:5LT1|rcsb pdb:5LT2|rcsb pdb:5LT3|rcsb pdb:5LT4|rcsb pdb:6OJQ|reactome:R-HSA-2132295|reactome:R-HSA-264876|reactome:R-HSA-5625970|reactome:R-HSA-6811434|reactome:R-HSA-983189|dip:DIP-29244N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:2UUVZBn5EAd0xBA5IZDPWHX9i7U9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N4S9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-6875061|uniprotkb:A1BQX0|uniprotkb:A1BQX1|uniprotkb:A8KA97|uniprotkb:Q96NM9|ensembl:ENSP00000323264|ensembl:ENSP00000480044|ensembl:ENSP00000480068|ensembl:ENSP00000494616 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mald2_human(display_long)|uniprotkb:MARVELD2(gene name)|psi-mi:MARVELD2(display_short)|uniprotkb:TRIC(gene name synonym)|uniprotkb:Tricellulin(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001033692.2|refseq:NP_001231663.1|refseq:XP_005248502.1|refseq:XP_005248503.1|refseq:XP_005248504.1|ensembl:ENSG00000152939(gene)|ensembl:ENSG00000274671(gene)|ensembl:ENST00000325631(transcript)|ensembl:ENST00000614617(transcript)|ensembl:ENST00000622835(transcript)|ensembl:ENST00000645446(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0033010"(paranodal junction)|go:"GO:0043220"(Schmidt-Lanterman incisure)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR008253(Marvel)|interpro:IPR010844(Occludin and RNA polymerase II elongation factor ELL)|interpro:IPR031176|interpro:IPR031177|rcsb pdb:5N7H|rcsb pdb:5N7I|rcsb pdb:5N7K - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WBHGueJq4y54+epedLVPcMvhhOU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T0W9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2556565|uniprotkb:Q96DQ2|uniprotkb:Q2M1P3|ensembl:ENSP00000304078 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:fa83b_human(display_long)|uniprotkb:C6orf143(gene name synonym)|uniprotkb:FAM83B(gene name)|psi-mi:FAM83B(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001010872.1|refseq:XP_011512696.1|refseq:XP_011512697.1|ensembl:ENSG00000168143(gene)|ensembl:ENST00000306858(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008283"(cell population proliferation)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0036313"(phosphatidylinositol 3-kinase catalytic subunit binding)|interpro:IPR012461(Protein of unknown function DUF1669)|rcsb pdb:5LZK|rcsb pdb:5QHI|rcsb pdb:5QHJ|rcsb pdb:5QHK|rcsb pdb:5QHL|rcsb pdb:5QHM|rcsb pdb:5QHN|rcsb pdb:5QHO|rcsb pdb:5QHP|rcsb pdb:5QHQ|rcsb pdb:5QHR|rcsb pdb:5QHS|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:XP_006715085.1|refseq:XP_016865967.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WzQTBg74ImTqkPDdKRM0YVcGXPY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NZ52 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-447404|uniprotkb:Q15017|uniprotkb:Q6IS16|uniprotkb:Q9UJY3|uniprotkb:B7Z7E2|uniprotkb:B7Z7M9|uniprotkb:J3KRN0|intact:EBI-28988067|ensembl:ENSP00000438085|ensembl:ENSP00000496890 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gga3_human(display_long)|uniprotkb:Golgi-localized, gamma ear-containing, ARF-binding protein 3(gene name synonym)|uniprotkb:GGA3(gene name)|psi-mi:GGA3(display_short)|uniprotkb:KIAA0154(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001278570.1|refseq:NP_001278571.1|refseq:NP_001166174.1|refseq:NP_054720.1|refseq:NP_619525.1|ensembl:ENST00000538886|ensembl:ENSP00000446421|ensembl:ENST00000578348|ensembl:ENSP00000463288|ensembl:ENST00000582717|ensembl:ENSP00000462081|ensembl:ENSP00000496890|ensembl:ENSP00000438085|refseq:NP_001166175.1|dip:DIP-31600N|ensembl:ENSG00000125447(gene)|ensembl:ENST00000537686(transcript)|ensembl:ENST00000649398(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0006622"(protein targeting to lysosome)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031648"(protein destabilization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|interpro:IPR002014(VHS)|interpro:IPR044111|mint:Q9NZ52|rcsb pdb:1JPL|rcsb pdb:1JUQ|rcsb pdb:1LF8|rcsb pdb:1P4U|rcsb pdb:1WR6|rcsb pdb:1YD8|reactome:R-HSA-8854214|reactome:R-HSA-8875656|reactome:R-HSA-977225|interpro:IPR004152(GAT)|interpro:IPR008152(Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain)|interpro:IPR008153(Clathrin adaptor, gamma-adaptin, appendage)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain)|interpro:IPR027422|interpro:IPR038425|interpro:IPR041198 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:MuqZi22xY1lyDboND7/xRNCqJbc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60763 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-356164|uniprotkb:B2RAQ0|uniprotkb:Q6PK63|uniprotkb:Q8N592|uniprotkb:Q86TB8|ensembl:ENSP00000444850|intact:EBI-21358067 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:uso1_human(display_long)|uniprotkb:USO1(gene name)|psi-mi:USO1(display_short)|uniprotkb:VDP(gene name synonym)|uniprotkb:Protein USO1 homolog(gene name synonym)|uniprotkb:Transcytosis-associated protein(gene name synonym)|uniprotkb:Vesicle-docking protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003706.2|refseq:NP_001276978.1|go:"GO:1900076"(regulation of cellular response to insulin stimulus)|interpro:IPR000225(Armadillo)|interpro:IPR006953(Uso1/p115 like vesicle tethering protein, head region)|interpro:IPR006955(Uso1/p115 like vesicle tethering protein, C-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR041209|mint:O60763|rcsb pdb:2W3C|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|go:"GO:0061025"(membrane fusion)|ensembl:ENSG00000138768(gene)|ensembl:ENST00000514213(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005795"(Golgi stack)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|go:"GO:0016020"(membrane)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0030133"(transport vesicle)|go:"GO:0032252"(secretory granule localization)|go:"GO:0045056"(transcytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0048211"(Golgi vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0048471"(perinuclear region of cytoplasm) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:qrBH7A4Ce+01K9Mu8cdVqMYUh4M9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UPX8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1570571|uniprotkb:Q3Y8G9|uniprotkb:Q52LK2|uniprotkb:Q9UKP1|uniprotkb:C0SPG8|uniprotkb:C0SPG9|ensembl:ENSP00000499561 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:shan2_human(display_long)|uniprotkb:Cortactin-binding protein 1(gene name synonym)|uniprotkb:SHANK2(gene name)|psi-mi:SHANK2(display_short)|uniprotkb:CORTBP1(gene name synonym)|uniprotkb:KIAA1022(gene name synonym)|uniprotkb:PROSAP1(gene name synonym)|uniprotkb:Proline-rich synapse-associated protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_573573.2|refseq:XP_005277989.1|refseq:NP_036441.2|refseq:XP_016872876.1|refseq:XP_016872877.1|dip:DIP-52255N|ensembl:ENSG00000162105(gene)|ensembl:ENST00000656230(transcript)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007416"(synapse assembly)|go:"GO:0007612"(learning)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030160"(synaptic receptor adaptor activity)|go:"GO:0030426"(growth cone)|go:"GO:0030534"(adult behavior)|go:"GO:0031526"(brush border membrane)|go:"GO:0035176"(social behavior)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0071625"(vocalization behavior)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR036028|interpro:IPR036034|interpro:IPR041489|mint:Q9UPX8|reactome:R-HSA-6794361 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GdGFkOKF29mMX0CkE2CM7ZYtkBI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6P3W7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1046810|uniprotkb:Q96EF4|uniprotkb:Q96ST4|uniprotkb:Q9H7V5|uniprotkb:Q9NVH3|uniprotkb:Q9P2I7|ensembl:ENSP00000354061|uniprotkb:A8KAB5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:scyl2_human(display_long)|uniprotkb:Coated vesicle-associated kinase of 104 kDa(gene name synonym)|uniprotkb:SCYL2(gene name)|psi-mi:SCYL2(display_short)|uniprotkb:CVAK104(gene name synonym)|uniprotkb:KIAA1360(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060458.3|ensembl:ENSG00000136021(gene)|ensembl:ENST00000360820(transcript)|go:"GO:0002092"(positive regulation of receptor internalization)|go:"GO:0004672"(protein kinase activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0007420"(brain development)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0021860"(pyramidal neuron development)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:2000286"(receptor internalization involved in canonical Wnt signaling pathway)|go:"GO:2000370"(positive regulation of clathrin-dependent endocytosis)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|mint:Q6P3W7|refseq:NP_001304713.1|refseq:NP_001317182.1|refseq:NP_001317183.1|refseq:NP_001317185.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:gYSfjHA8PY8nvLrWxnm2RxpNdnY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WU90 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1042636|uniprotkb:Q5QTQ4|uniprotkb:Q8WZ06|uniprotkb:Q9NUZ3|uniprotkb:Q9P079|uniprotkb:Q9NZ37|uniprotkb:B4DMW2|uniprotkb:D3DPG7|ensembl:ENSP00000338788 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zc3hf_human(display_long)|uniprotkb:ZC3H15(gene name)|psi-mi:ZC3H15(display_short)|uniprotkb:DFRP1(gene name synonym)|uniprotkb:LEREPO4(gene name synonym)|uniprotkb:DRG family-regulatory protein 1(gene name synonym)|uniprotkb:Likely ortholog of mouse immediate early response erythropoietin 4(gene name synonym)|uniprotkb:HSPC303(orf name)|uniprotkb:HT010(orf name)|uniprotkb:MSTP012(orf name)|uniprotkb:PP730(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060941.2|ensembl:ENSG00000065548(gene)|ensembl:ENST00000337859(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR032378|interpro:IPR036855|interpro:IPR041367|mint:Q8WU90 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:MrcssHMHDoQKqsIXdhfMWOnHlBY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P40121 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4291044|uniprotkb:D6W5K8|uniprotkb:Q53SA7|ensembl:ENSP00000263867|ensembl:ENSP00000386315|ensembl:ENSP00000386965|uniprotkb:B8ZZS7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:capg_human(display_long)|uniprotkb:CAPG(gene name)|psi-mi:CAPG(display_short)|uniprotkb:AFCP(gene name synonym)|uniprotkb:MCP(gene name synonym)|uniprotkb:Actin regulatory protein CAP-G(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001738.2|refseq:XP_011531424.1|refseq:XP_011531425.1|refseq:NP_001243068.1|ensembl:ENSG00000042493(gene)|ensembl:ENST00000263867(transcript)|ensembl:ENST00000409670(transcript)|ensembl:ENST00000409724(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0007417"(central nervous system development)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0042470"(melanosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051014"(actin filament severing)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090543"(Flemming body)|interpro:IPR007122(Gelsolin)|interpro:IPR007123(Gelsolin region)|interpro:IPR029006|interpro:IPR029917|mint:P40121|rcsb pdb:1J72|rcsb pdb:1JHW|refseq:NP_001307661.1|refseq:NP_001307662.1|refseq:NP_001243069.1|dip:DIP-61547N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:QgyN9LayNHJZaKZygTug8GAs6QE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UHX1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1053259|uniprotkb:Q969E7|uniprotkb:Q96D94|uniprotkb:Q96H63|uniprotkb:Q99628|uniprotkb:Q9NZA0|uniprotkb:Q9UJY7|uniprotkb:A8K8K8|ensembl:ENSP00000434359|ensembl:ENSP00000484860 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:puf60_human(display_long)|uniprotkb:"60 kDa poly(U)-binding-splicing factor"(gene name synonym)|uniprotkb:FUSE-binding protein-interacting repressor(gene name synonym)|uniprotkb:Siah-binding protein 1(gene name synonym)|uniprotkb:Ro-binding protein 1(gene name synonym)|uniprotkb:PUF60(gene name)|psi-mi:PUF60(display_short)|uniprotkb:SIAHBP1(gene name synonym)|uniprotkb:FIR(gene name synonym)|uniprotkb:ROBPI(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001129505.1|refseq:NP_055096.2|refseq:NP_510965.1|refseq:NP_001258026.1|refseq:NP_001258028.1|refseq:NP_001258029.1|refseq:NP_001258025.1|refseq:NP_001258027.1|interpro:IPR034211|interpro:IPR034212|interpro:IPR035979|mint:Q9UHX1|rcsb pdb:2DNY|rcsb pdb:2KXF|rcsb pdb:2KXH|rcsb pdb:2QFJ|rcsb pdb:3DXB|rcsb pdb:3UE2|ensembl:ENSG00000179950(gene)|ensembl:ENSG00000274081(gene)|ensembl:ENST00000526683(transcript)|ensembl:ENST00000620341(transcript)|rcsb pdb:3US5|go:"GO:0000380"(alternative mRNA splicing, via spliceosome)|rcsb pdb:3UWT|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006376"(mRNA splice site selection)|go:"GO:0006915"(apoptotic process)|go:"GO:0030054"(cell junction)|rcsb pdb:5KVY|rcsb pdb:5KW1|rcsb pdb:5KW6|rcsb pdb:5KWQ|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR006532(Poly-U binding splicing factor, half-pint)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034209|rcsb pdb:6LUR|rcsb pdb:6SLO|reactome:R-HSA-72163|refseq:XP_016868728.1|refseq:XP_016868729.1|dip:DIP-34636N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:nL6ALA543VdThkempiJTWAOhoNA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TF74 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2850112|uniprotkb:Q8TE44|uniprotkb:A8K0L3|uniprotkb:Q658J8|uniprotkb:Q71RE1|ensembl:ENSP00000320924|ensembl:ENSP00000462350|ensembl:ENSP00000462826 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:wipf2_human(display_long)|uniprotkb:WIPF2(gene name)|psi-mi:WIPF2(display_short)|uniprotkb:WICH(gene name synonym)|uniprotkb:WIRE(gene name synonym)|uniprotkb:WASP-interacting protein-related protein(gene name synonym)|uniprotkb:WIP- and CR16-homologous protein(gene name synonym)|uniprotkb:WIP-related protein(gene name synonym)|uniprotkb:PP10631(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000320924|ensembl:ENSP00000462350|ensembl:ENSP00000462826|refseq:XP_011522715.1|refseq:NP_573571.1|refseq:XP_005257140.1|refseq:XP_005257141.1|ensembl:ENSG00000171475(gene)|ensembl:ENST00000323571(transcript)|ensembl:ENST00000583130(transcript)|ensembl:ENST00000585043(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0030048"(actin filament-based movement)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028294|reactome:R-HSA-2029482|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013409|reactome:R-HSA-9664422 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xnXvZLySNsfyWjL2lkAMUH16hlU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6ZN28 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2483498|ensembl:ENSP00000328410|ensembl:ENSP00000383185|ensembl:ENSP00000466864|uniprotkb:A8MUS5|uniprotkb:B2RNR9|uniprotkb:Q6ZQN8|uniprotkb:Q7Z5A5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:macc1_human(display_long)|uniprotkb:MACC1(gene name)|psi-mi:MACC1(display_short)|uniprotkb:SH3 domain-containing protein 7a5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000183742(gene)|ensembl:ENST00000332878(transcript)|ensembl:ENST00000400331(transcript)|ensembl:ENST00000589011(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0008083"(growth factor activity)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051781"(positive regulation of cell division)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|refseq:NP_877439.3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:oxGaJSY19Sf/hU0oQbtMH3sIyLc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75044 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1051034|ensembl:ENSP00000459615|uniprotkb:A2RUF3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:srgp2_human(display_long)|uniprotkb:Formin-binding protein 2(gene name synonym)|uniprotkb:SRGAP2(gene name)|psi-mi:SRGAP2(display_short)|uniprotkb:FNBP2(gene name synonym)|uniprotkb:KIAA0456(gene name synonym)|uniprotkb:ARHGAP34(gene name synonym)|uniprotkb:Rho GTPase-activating protein 34(gene name synonym)|uniprotkb:SRGAP2A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001164108.1|refseq:NP_056141.2|ensembl:ENSG00000266028(gene)|ensembl:ENST00000573034(transcript)|go:"GO:0003363"(lamellipodium assembly involved in ameboidal cell migration)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021816"(extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044327"(dendritic spine head)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051014"(actin filament severing)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0060996"(dendritic spine development)|go:"GO:2001223"(negative regulation of neuron migration)|interpro:IPR000198(RhoGAP)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR030252|interpro:IPR031160|interpro:IPR035648|interpro:IPR036028|mint:O75044|rcsb pdb:2DL8|rcsb pdb:4RTT|rcsb pdb:4RUG|rcsb pdb:5I6J|rcsb pdb:5I6R|rcsb pdb:5I7D|reactome:R-HSA-428543|reactome:R-HSA-5663220|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9035034|dip:DIP-37618N|refseq:XP_005277567.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/0NBTrPy/51L4LGytNP/80OifEE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P62258 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-356498|uniprotkb:P29360|uniprotkb:P42655|uniprotkb:Q53XZ5|uniprotkb:Q63631|uniprotkb:Q7M4R4|uniprotkb:B3KY71|uniprotkb:D3DTH5|uniprotkb:Q4VJB6|ensembl:ENSP00000264335|ensembl:ENSP00000487356 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:1433e_human(display_long)|uniprotkb:YWHAE(gene name)|psi-mi:YWHAE(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006752.1|dip:DIP-36676N|reactome:R-HSA-1445148|reactome:R-HSA-2028269|reactome:R-HSA-205025|reactome:R-HSA-2565942|reactome:R-HSA-3371453|reactome:R-HSA-3371511|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-8854518|reactome:R-HSA-8862803|reactome:R-HSA-8876198|ensembl:ENSG00000108953(gene)|ensembl:ENSG00000274474(gene)|ensembl:ENST00000264335(transcript)|ensembl:ENST00000627231(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0003064"(regulation of heart rate by hormone)|go:"GO:0003723"(RNA binding)|go:"GO:0005246"(calcium channel regulator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005871"(kinesin complex)|go:"GO:0005925"(focal adhesion)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0034504"(protein localization to nucleus)|go:"GO:0034605"(cellular response to heat)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0060306"(regulation of membrane repolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086013"(membrane repolarization during cardiac muscle cell action potential)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090724"(central region of growth cone)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:1901016"(regulation of potassium ion transmembrane transporter activity)|go:"GO:1901020"(negative regulation of calcium ion transmembrane transporter activity)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|go:"GO:1905913"(negative regulation of calcium ion export across plasma membrane)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P62258|rcsb pdb:2BR9|rcsb pdb:3UAL|rcsb pdb:3UBW|rcsb pdb:6EIH|rcsb pdb:7C8E|reactome:R-HSA-111447 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:mnuAjdnQZbMFojll2PnV3xFklXQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O43639 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-713635|uniprotkb:Q9BWN9|uniprotkb:Q9UIC3|ensembl:ENSP00000233154|ensembl:ENSP00000377018|uniprotkb:D3DVK1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nck2_human(display_long)|uniprotkb:NCK adaptor protein 2(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-beta(gene name synonym)|uniprotkb:NCK2(gene name)|psi-mi:NCK2(display_short)|uniprotkb:GRB4(gene name synonym)|uniprotkb:Growth factor receptor-bound protein 4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_006712860.1|refseq:NP_001004720.1|refseq:NP_003572.2|ensembl:ENSG00000071051(gene)|ensembl:ENST00000233154(transcript)|ensembl:ENST00000393349(transcript)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0007015"(actin filament organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007176"(regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016477"(cell migration)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0060996"(dendritic spine development)|go:"GO:0097110"(scaffold protein binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028524|interpro:IPR035559|interpro:IPR035560|interpro:IPR035561|interpro:IPR035883|interpro:IPR036028|interpro:IPR036860|mint:O43639|rcsb pdb:1U5S|rcsb pdb:1WX6|rcsb pdb:1Z3K|rcsb pdb:2B86|rcsb pdb:2CIA|rcsb pdb:2FRW|rcsb pdb:2FRY|rcsb pdb:2JXB|rcsb pdb:4E6R|reactome:R-HSA-186763|reactome:R-HSA-373753|reactome:R-HSA-3928664|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-8985801|reactome:R-HSA-9013420|reactome:R-HSA-9013424|refseq:XP_016860592.1|refseq:XP_016860593.1|refseq:XP_016860594.1|refseq:XP_011510293.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WV9nJ78Im/ga5KQlRuSN2ODzWpQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O14562 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-9827160|uniprotkb:A8MW58|uniprotkb:D3DWF2|ensembl:ENSP00000379217 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ubfd1_human(display_long)|uniprotkb:UBFD1(gene name)|psi-mi:UBFD1(display_short)|uniprotkb:UBPH(gene name synonym)|uniprotkb:Ubiquitin-binding protein homolog(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_061989.2|ensembl:ENSG00000103353(gene)|ensembl:ENST00000395878(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR000626(Ubiquitin)|interpro:IPR019954|interpro:IPR029071|interpro:IPR039120 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:pWvmBkLwmjju7WmGNnyjZKzq7MI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NVD7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-747655|uniprotkb:Q96C85|uniprotkb:Q9HA48|ensembl:ENSP00000334008 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:parva_human(display_long)|uniprotkb:Calponin-like integrin-linked kinase-binding protein(gene name synonym)|uniprotkb:CH-ILKBP(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 2(gene name synonym)|uniprotkb:Actopaxin(gene name synonym)|uniprotkb:PARVA(gene name)|psi-mi:PARVA(display_short)|uniprotkb:MXRA2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060692.2|ensembl:ENSG00000197702(gene)|ensembl:ENST00000334956(transcript)|go:"GO:0002040"(sprouting angiogenesis)|go:"GO:0003148"(outflow tract septum morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030031"(cell projection assembly)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0060271"(cilium assembly)|go:"GO:0070252"(actin-mediated cell contraction)|go:"GO:0071670"(smooth muscle cell chemotaxis)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR028433|interpro:IPR036872|mint:Q9NVD7|rcsb pdb:2K2R|rcsb pdb:2VZC|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3KMU|rcsb pdb:3KMW|rcsb pdb:3REP|reactome:R-HSA-446343|reactome:R-HSA-446353|reactome:R-HSA-446388|go:"GO:0005829"(cytosol)|rcsb pdb:6MIB - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:KjiRqYX7cAl33+lH1FnFGfkaZsM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UHR4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2483278|ensembl:ENSP00000005260|uniprotkb:A4D268|uniprotkb:Q75L21|uniprotkb:Q75L22|uniprotkb:Q96CV4|uniprotkb:Q9H5F5|uniprotkb:Q9Y2M8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:bi2l1_human(display_long)|uniprotkb:BAIAP2L1(gene name)|psi-mi:BAIAP2L1(display_short)|uniprotkb:IRTKS(gene name synonym)|uniprotkb:Insulin receptor tyrosine kinase substrate(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000006453(gene)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|ensembl:ENST00000005260(transcript)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0009617"(response to bacterium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0046626"(regulation of insulin receptor signaling pathway)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030060|interpro:IPR035592|interpro:IPR036028|rcsb pdb:2KXC|rcsb pdb:2LNH|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9035034|refseq:NP_061330.2|ensembl:ENSP00000005260|dip:DIP-53820N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ig7xSOv8h6Y4vYE0/n228+ZLWaM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O14530 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-707554|uniprotkb:D3DVI4|uniprotkb:Q53RV8|uniprotkb:Q6NSF5|uniprotkb:Q9BRU6|uniprotkb:B2R9G8|uniprotkb:Q53HG4|uniprotkb:Q8TB70|ensembl:ENSP00000264255 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:txnd9_human(display_long)|uniprotkb:Protein 1-4(gene name synonym)|uniprotkb:ATP-binding protein associated with cell differentiation(gene name synonym)|uniprotkb:TXNDC9(gene name)|psi-mi:TXNDC9(display_short)|uniprotkb:APACD(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005774.2|ensembl:ENSG00000115514(gene)|ensembl:ENST00000264255(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR036249 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:juH2+xAayd3ASfZg1RBQ30ewQ8k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BYI3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11065686|uniprotkb:A0A024RA06|uniprotkb:A4D145|uniprotkb:B8ZZJ1|uniprotkb:Q6N010|uniprotkb:Q75MR4|uniprotkb:Q7LDZ4|uniprotkb:Q96MX1|uniprotkb:Q96NQ6|ensembl:ENSP00000403396|intact:EBI-16428864 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:hycci_human(display_long)|uniprotkb:FAM126A(gene name)|psi-mi:FAM126A(display_short)|uniprotkb:DRCTNNB1A(gene name synonym)|uniprotkb:Down-regulated by CTNNB1 protein A(gene name synonym)|uniprotkb:Protein FAM126A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_115970.2|refseq:XP_011513891.1|refseq:XP_005249951.1|ensembl:ENSG00000122591(gene)|ensembl:ENST00000432176(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0042552"(myelination)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR018619|rcsb pdb:5DSE|rcsb pdb:6BQ1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:dQX246o/4bB9UkgG+9Be4mIOfxU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NBN3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2687855|uniprotkb:Q9P103|uniprotkb:Q9Y3Y7|uniprotkb:Q9BS46|uniprotkb:Q6NT77|uniprotkb:Q8NCA4|ensembl:ENSP00000374484 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tm87a_human(display_long)|uniprotkb:PSEC0094(orf name)|uniprotkb:TMEM87A(gene name)|psi-mi:TMEM87A(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001273416.1|refseq:NP_001103973.1|refseq:NP_056312.2|ensembl:ENSG00000103978(gene)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|interpro:IPR009637(Transmembrane receptor, eukaryota)|reactome:R-HSA-8980692|ensembl:ENST00000389834(transcript)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GdHPH2U8wRKfLAAUi0q2lw4ZtCA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y5X1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-77848|ensembl:ENSP00000376024|ensembl:ENSP00000506326|uniprotkb:Q9BSI7|uniprotkb:Q9BVM1|uniprotkb:Q9UJH6|uniprotkb:Q9UP20 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snx9_human(display_long)|uniprotkb:SNX9(gene name)|psi-mi:SNX9(display_short)|uniprotkb:SH3PX1(gene name synonym)|uniprotkb:SH3PXD3A(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 1(gene name synonym)|uniprotkb:SH3 and PX domain-containing protein 3A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000130340(gene)|ensembl:ENST00000392185(transcript)|ensembl:ENST00000679814(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0001726"(ruffle)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0016197"(endosomal transport)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032437"(cuticular plate)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0036089"(cleavage furrow formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0060988"(lipid tube assembly)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001452(Src homology-3)|interpro:IPR001683(Phox-like)|interpro:IPR014536(Sorting nexin, Snx9 type)|interpro:IPR019497|interpro:IPR027267|interpro:IPR028644|interpro:IPR035558|interpro:IPR036028|interpro:IPR036871|interpro:IPR037425|interpro:IPR037426|mint:Q9Y5X1|rcsb pdb:2RAI|rcsb pdb:2RAJ|rcsb pdb:2RAK|rcsb pdb:3DYT|rcsb pdb:3DYU|rcsb pdb:3LGE|reactome:R-HSA-432722|reactome:R-HSA-8856828|refseq:NP_057308.1|dip:DIP-30997N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:qtqmMew2psrK6OJPAOWQGTVmNJA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UGI8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2561654|uniprotkb:Q9HAJ9|uniprotkb:Q9GZQ1|uniprotkb:A4D0U6|ensembl:ENSP00000350937 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tes_human(display_long)|uniprotkb:TESS(gene name synonym)|uniprotkb:TES(gene name)|psi-mi:TES(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_056456.1|refseq:NP_690042.1|ensembl:ENSG00000135269(gene)|ensembl:ENST00000358204(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0030054"(cell junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045296"(cadherin binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR010442(PET)|interpro:IPR027683|interpro:IPR033724|interpro:IPR034958|interpro:IPR034959|interpro:IPR034960|mint:Q9UGI8|rcsb pdb:2IYB|rcsb pdb:2XQN - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:19bO7/55OMgcMT5lx1404AluskE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96B97 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-346595|uniprotkb:Q8IWX6|uniprotkb:Q8IX98|uniprotkb:Q96RN4|uniprotkb:Q9NYR0|uniprotkb:B7Z1D5|uniprotkb:Q5JPT4|uniprotkb:Q5JPT5|ensembl:ENSP00000380921 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sh3k1_human(display_long)|uniprotkb:SH3KBP1(gene name)|psi-mi:SH3KBP1(display_short)|uniprotkb:CIN85(gene name synonym)|uniprotkb:Cbl-interacting protein of 85 kDa(gene name synonym)|uniprotkb:Human Src family kinase-binding protein 1(gene name synonym)|uniprotkb:CD2-binding protein 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001019837.1|refseq:NP_114098.1|refseq:NP_001171889.1|refseq:XP_016884958.1|dip:DIP-31803N|ensembl:ENSG00000147010(gene)|ensembl:ENST00000397821(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0043005"(neuron projection)|go:"GO:0045202"(synapse)|go:"GO:0050871"(positive regulation of B cell activation)|interpro:IPR001452(Src homology-3)|interpro:IPR028506|interpro:IPR035770|interpro:IPR035771|interpro:IPR035772|interpro:IPR036028|mint:Q96B97|rcsb pdb:2BZ8|rcsb pdb:2K6D|rcsb pdb:2K9G|rcsb pdb:2N64|rcsb pdb:2O2O|rcsb pdb:2YDL|rcsb pdb:5ABS|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866376|reactome:R-HSA-8875360|reactome:R-HSA-983695|go:"GO:0007015"(actin filament organization) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WB37Fbtwe/IA57zPOHhbmdNNI1s9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q92997 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-739789|uniprotkb:O14642|uniprotkb:Q13531|uniprotkb:Q8N5E9|uniprotkb:Q92607|uniprotkb:D3DNT0|intact:EBI-11081380|uniprotkb:B4E3E5|ensembl:ENSP00000316054 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dvl3_human(display_long)|uniprotkb:DVL3(gene name)|psi-mi:DVL3(display_short)|uniprotkb:KIAA0208(gene name synonym)|uniprotkb:DSH homolog 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004414.3|dip:DIP-34509N|ensembl:ENSG00000161202(gene)|ensembl:ENST00000313143(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005109"(frizzled binding)|go:"GO:0005829"(cytosol)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035567"(non-canonical Wnt signaling pathway)|go:"GO:0038031"(non-canonical Wnt signaling pathway via JNK cascade)|go:"GO:0042493"|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050821"(protein stabilization)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060071"(Wnt signaling pathway, planar cell polarity pathway)|go:"GO:0090179"(planar cell polarity pathway involved in neural tube closure)|go:"GO:0150012"(positive regulation of neuron projection arborization)|go:"GO:1903827"|interpro:IPR000591(Pleckstrin/ G-protein, interacting region)|interpro:IPR001158(DIX)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR003351(Dishevelled protein)|interpro:IPR008339(Dishevelled region)|interpro:IPR008342(Dishevelled-3 protein, C-terminal)|interpro:IPR015506(Dishevelled related protein)|interpro:IPR024580|interpro:IPR029071|interpro:IPR036034|interpro:IPR036388|interpro:IPR036390|interpro:IPR038207|mint:Q92997|rcsb pdb:6V7O|rcsb pdb:6ZC6|rcsb pdb:6ZC8|reactome:R-HSA-201681|reactome:R-HSA-201688|reactome:R-HSA-4086400|reactome:R-HSA-4641258|reactome:R-HSA-4641262|reactome:R-HSA-5368598|reactome:R-HSA-5663220|reactome:R-HSA-9673324 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yJ3YIp5IhvKTQwa3bK5yTjNyqXk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NR46 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-749607|uniprotkb:A8MPS4|uniprotkb:Q8WY61|uniprotkb:Q96JH9|uniprotkb:A6NC47|ensembl:ENSP00000361640|ensembl:ENSP00000361645 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:shlb2_human(display_long)|uniprotkb:SH3 domain-containing GRB2-like protein B2(gene name synonym)|uniprotkb:SH3GLB2(gene name)|psi-mi:SH3GLB2(display_short)|uniprotkb:KIAA1848(gene name synonym)|uniprotkb:PP578(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_064530.1|refseq:NP_001273974.1|refseq:NP_001273975.1|refseq:XP_005252158.1|ensembl:ENSG00000148341(gene)|ensembl:ENST00000372559(transcript)|ensembl:ENST00000372564(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR035640|interpro:IPR036028|mint:Q9NR46 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9C0QF9xLb5A6eYQBK2aU/J1aGVo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H3Q1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-744665|uniprotkb:O95828|uniprotkb:Q96FT3|ensembl:ENSP00000338258|uniprotkb:B3KUS7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:borg4_human(display_long)|uniprotkb:Binder of Rho GTPases 4(gene name synonym)|uniprotkb:CDC42EP4(gene name)|psi-mi:CDC42EP4(display_short)|uniprotkb:BORG4(gene name synonym)|uniprotkb:CEP4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_036253.2|ensembl:ENSG00000179604(gene)|ensembl:ENST00000335793(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR029273|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|refseq:XP_005257239.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:HC1q85v0D6AOKZ82FKaBdAEv1mE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q99497 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1164361|uniprotkb:O14805|uniprotkb:Q6DR95|uniprotkb:Q7LFU2|uniprotkb:B2R4Z1|ensembl:ENSP00000340278|ensembl:ENSP00000366708|ensembl:ENSP00000366711|ensembl:ENSP00000418770|ensembl:ENSP00000465404 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:park7_human(display_long)|uniprotkb:PARK7(gene name)|psi-mi:PARK7(display_short)|uniprotkb:Oncogene DJ1(gene name synonym)|uniprotkb:Parkinsonism-associated deglycase(gene name synonym)|uniprotkb:Maillard deglycase(gene name synonym)|uniprotkb:Protein DJ-1(gene name synonym)|uniprotkb:Protein/nucleic acid deglycase DJ-1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001116849.1|refseq:NP_009193.2|refseq:XP_005263481.1|go:"GO:0046295"(glycolate biosynthetic process)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050681"(androgen receptor binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0050787"(detoxification of mercury ion)|go:"GO:0050821"(protein stabilization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051444"(negative regulation of ubiquitin-protein transferase activity)|go:"GO:0051583"(dopamine uptake involved in synaptic transmission)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051899"(membrane depolarization)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0060081"(membrane hyperpolarization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0060765"(regulation of androgen receptor signaling pathway)|go:"GO:0061727"(methylglyoxal catabolic process to lactate)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070994"(detection of oxidative stress)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098793"(presynapse)|go:"GO:0106044"(guanine deglycation)|go:"GO:0106045"(guanine deglycation, methylglyoxal removal)|go:"GO:0106046"(guanine deglycation, glyoxal removal)|go:"GO:0110095"(cellular detoxification of aldehyde)|go:"GO:0140041"(cellular detoxification of methylglyoxal)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901671"(positive regulation of superoxide dismutase activity)|go:"GO:1901984"(negative regulation of protein acetylation)|go:"GO:1902177"(positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902903"(regulation of supramolecular fiber organization)|go:"GO:1902958"(positive regulation of mitochondrial electron transport, NADH to ubiquinone)|go:"GO:1903073"(negative regulation of death-inducing signaling complex assembly)|go:"GO:1903094"(negative regulation of protein K48-linked deubiquitination)|go:"GO:1903122"(negative regulation of TRAIL-activated apoptotic signaling pathway)|go:"GO:1903135"(cupric ion binding)|go:"GO:1903136"(cuprous ion binding)|go:"GO:1903168"(positive regulation of pyrroline-5-carboxylate reductase activity)|go:"GO:1903178"(positive regulation of tyrosine 3-monooxygenase activity)|go:"GO:1903181"(positive regulation of dopamine biosynthetic process)|go:"GO:1903189"(glyoxal metabolic process)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:1903200"(positive regulation of L-dopa decarboxylase activity)|go:"GO:1903202"(negative regulation of oxidative stress-induced cell death)|go:"GO:1903206"(negative regulation of hydrogen peroxide-induced cell death)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1903377"(negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903384"(negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway)|go:"GO:1903427"(negative regulation of reactive oxygen species biosynthetic process)|go:"GO:1903428"(positive regulation of reactive oxygen species biosynthetic process)|go:"GO:1903599"(positive regulation of autophagy of mitochondrion)|go:"GO:1905259"(negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990381"(ubiquitin-specific protease binding)|go:"GO:1990422"("glyoxalase (glycolic acid-forming) activity")|go:"GO:2000157"(negative regulation of ubiquitin-specific protease activity)|go:"GO:2000277"(positive regulation of oxidative phosphorylation uncoupler activity)|go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|go:"GO:2000825"(positive regulation of androgen receptor activity)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001268"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway)|interpro:IPR002818(ThiJ/PfpI)|interpro:IPR006287(DJ-1)|interpro:IPR029062|go:"GO:1903197"(positive regulation of L-dopa biosynthetic process)|rcsb pdb:3B36|rcsb pdb:3B38|rcsb pdb:3B3A|rcsb pdb:3BWE|rcsb pdb:3CY6|rcsb pdb:3CYF|rcsb pdb:3CZ9|rcsb pdb:3CZA|rcsb pdb:3EZG|mint:Q99497|rcsb pdb:1J42|rcsb pdb:1P5F|rcsb pdb:3F71|rcsb pdb:1PDV|rcsb pdb:1PDW|rcsb pdb:1PE0|rcsb pdb:1Q2U|rcsb pdb:3SF8|rcsb pdb:1SOA|rcsb pdb:1UCF|rcsb pdb:2OR3|rcsb pdb:2R1T|rcsb pdb:2R1U|rcsb pdb:2R1V|rcsb pdb:4BTE|rcsb pdb:2RK3|rcsb pdb:2RK4|rcsb pdb:2RK6|ensembl:ENSG00000116288(gene)|ensembl:ENST00000338639(transcript)|ensembl:ENST00000377488(transcript)|ensembl:ENST00000377491(transcript)|ensembl:ENST00000493678(transcript)|ensembl:ENST00000493373(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0002866"(positive regulation of acute inflammatory response to antigenic stimulus)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003729"(mRNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006281"(DNA repair)|rcsb pdb:4MTC|rcsb pdb:4N0M|rcsb pdb:4N12|rcsb pdb:4OGF|rcsb pdb:4OQ4|rcsb pdb:4P2G|rcsb pdb:4P34|rcsb pdb:4P35|rcsb pdb:4P36|rcsb pdb:4RKW|rcsb pdb:4RKY|rcsb pdb:4S0Z|rcsb pdb:4ZGG|rcsb pdb:5IP5|rcsb pdb:5SY6|rcsb pdb:5SY9|rcsb pdb:5SYA|rcsb pdb:6AF5|rcsb pdb:6AF7|rcsb pdb:6AF9|rcsb pdb:6AFA|rcsb pdb:6AFB|rcsb pdb:6AFC|rcsb pdb:6AFD|rcsb pdb:6AFE|rcsb pdb:6AFF|rcsb pdb:6AFG|rcsb pdb:6AFH|rcsb pdb:6AFI|rcsb pdb:6AFJ|rcsb pdb:6AFL|rcsb pdb:6E5Z|rcsb pdb:6M8Z|rcsb pdb:7C62|reactome:R-HSA-3899300|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9646399|rcsb pdb:4MNT|go:"GO:0006517"(protein deglycosylation)|go:"GO:0006914"(autophagy)|go:"GO:0006954"(inflammatory response)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007338"(single fertilization)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008233"(peptidase activity)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009438"(methylglyoxal metabolic process)|go:"GO:0010273"(detoxification of copper ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016532"(superoxide dismutase copper chaperone activity)|go:"GO:0016570"(histone modification)|go:"GO:0016605"(PML body)|go:"GO:0016684"(oxidoreductase activity, acting on peroxide as acceptor)|go:"GO:0019249"(lactate biosynthetic process)|go:"GO:0019826"(oxygen sensor activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019955"(cytokine binding)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0030424"(axon)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032148"(activation of protein kinase B activity)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033182"(regulation of histone ubiquitination)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0033864"("positive regulation of NAD(P)H oxidase activity")|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035065"(regulation of histone acetylation)|go:"GO:0036470"(tyrosine 3-monooxygenase activator activity)|go:"GO:0036471"(cellular response to glyoxal)|go:"GO:0036478"(L-dopa decarboxylase activator activity)|go:"GO:0036524"(protein deglycase activity)|go:"GO:0036526"(peptidyl-cysteine deglycation)|go:"GO:0036527"(peptidyl-arginine deglycation)|go:"GO:0036528"(peptidyl-lysine deglycation)|go:"GO:0036529"(protein deglycation, glyoxal removal)|go:"GO:0036530"(protein deglycation, methylglyoxal removal)|go:"GO:0036531"(glutathione deglycation)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043523"(regulation of neuron apoptotic process)|go:"GO:0043524"(negative regulation of neuron apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0030073"(insulin secretion)|go:"GO:0044388"(small protein activating enzyme binding)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045340"(mercury ion binding)|dip:DIP-35515N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:i5ah4UPCf+4cD51ClZNggMFJMDo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q16658 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351076|uniprotkb:Q96IH1|uniprotkb:A6NI89|uniprotkb:Q96IC5|uniprotkb:Q9BRF1|uniprotkb:B2RE97|ensembl:ENSP00000371798 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:fscn1_human(display_long)|uniprotkb:FSCN1(gene name)|psi-mi:FSCN1(display_short)|uniprotkb:FAN1(gene name synonym)|uniprotkb:HSN(gene name synonym)|uniprotkb:SNL(gene name synonym)|uniprotkb:Singed-like protein(gene name synonym)|uniprotkb:55 kDa actin-bundling protein(gene name synonym)|uniprotkb:p55(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030046"(parallel actin filament bundle assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031253"(cell projection membrane)|go:"GO:0032534"(regulation of microvillus assembly)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0044393"(microspike)|go:"GO:0045296"(cadherin binding)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:0090091"(positive regulation of extracellular matrix disassembly)|interpro:IPR008999(Actin_cross-linking)|interpro:IPR010431(Fascin)|interpro:IPR022768|interpro:IPR024703|interpro:IPR030146|mint:Q16658|rcsb pdb:1DFC|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030035"(microspike assembly)|rcsb pdb:3LLP|refseq:NP_003079.1|ensembl:ENSG00000075618(gene)|ensembl:ENST00000382361(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005902"(microvillus)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0008144"(obsolete drug binding)|rcsb pdb:3P53|rcsb pdb:4GOV|rcsb pdb:4GOY|rcsb pdb:4GP3|rcsb pdb:6B0T|rcsb pdb:6I0Z|rcsb pdb:6I10|rcsb pdb:6I11|rcsb pdb:6I12|rcsb pdb:6I13|rcsb pdb:6I14|rcsb pdb:6I15|rcsb pdb:6I16|rcsb pdb:6I17|rcsb pdb:6I18|reactome:R-HSA-6785807|rcsb pdb:4GP0|dip:DIP-33171N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yc9EJDCKGJGGEcEueR/yAY/fxRg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NTK5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-766468|uniprotkb:Q5BJD7|uniprotkb:Q8NCI8|uniprotkb:Q96CU1|uniprotkb:Q96SV2|uniprotkb:Q9P1D3|uniprotkb:Q9UNY9|uniprotkb:Q9Y6G4|uniprotkb:D7EHM2|ensembl:ENSP00000284719 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ola1_human(display_long)|uniprotkb:GTPBP9(gene name synonym)|uniprotkb:GTP-binding protein 9(gene name synonym)|uniprotkb:OLA1(gene name)|psi-mi:OLA1(display_short)|uniprotkb:PTD004(orf name)|uniprotkb:PRO2455(orf name)|uniprotkb:DNA damage-regulated overexpressed in cancer 45(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001011708.1|refseq:NP_037473.3|dip:DIP-34591N|ensembl:ENST00000284719(transcript)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0016787"(hydrolase activity)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR004095(TGS)|interpro:IPR004396(Conserved hypothetical protein CHP00092)|interpro:IPR006073(GTP1/OBG)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR013029(Protein of unknown function DUF933)|interpro:IPR023192|interpro:IPR027417|interpro:IPR031167|interpro:IPR041706|mint:Q9NTK5|rcsb pdb:2OHF|reactome:R-HSA-114608|ensembl:ENSG00000138430(gene) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:aQk5XBcKpx1YSW4mHtyRsTpimvk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N9N7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4290511|uniprotkb:Q7Z2Z6|uniprotkb:Q8N1T6|ensembl:ENSP00000326817|ensembl:ENSP00000380319|ensembl:ENSP00000455445 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lrc57_human(display_long)|uniprotkb:LRRC57(gene name)|psi-mi:LRRC57(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000180979(gene)|ensembl:ENST00000323443(transcript)|ensembl:ENST00000397130(transcript)|ensembl:ENST00000563454(transcript)|go:"GO:0016020"(membrane)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|go:"GO:0070062"(extracellular exosome)|refseq:NP_694992.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0AwiIo1X4p5m32JCTCQswlwyH6k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N3F8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1056885|uniprotkb:Q5TI16|uniprotkb:Q7RTP5|uniprotkb:Q8N3N8|uniprotkb:Q9BVL9|uniprotkb:Q9BY92|uniprotkb:Q9UH43|uniprotkb:Q9UH44|uniprotkb:Q9UH45|ensembl:ENSP00000215957 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:milk1_human(display_long)|uniprotkb:MICALL1(gene name)|psi-mi:MICALL1(display_short)|uniprotkb:KIAA1668(gene name synonym)|uniprotkb:MIRAB13(gene name synonym)|uniprotkb:Molecule interacting with Rab13(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_203744.1|ensembl:ENSP00000215957|ensembl:ENSG00000100139(gene)|ensembl:ENST00000215957(transcript)|go:"GO:0005770"(late endosome)|go:"GO:0006612"(protein targeting to membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0032458"(slow endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR022735|interpro:IPR028563|interpro:IPR036872|mint:Q8N3F8|rcsb pdb:2KSP|go:"GO:0045296"(cadherin binding) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:G64P9EtjEfLIVLYkb+w3vCWaT0w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75874 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-715695|uniprotkb:Q567U4|uniprotkb:Q6FHQ6|uniprotkb:Q7Z3V0|uniprotkb:Q93090|uniprotkb:Q9NTJ9|uniprotkb:Q9UKW8|ensembl:ENSP00000260985|ensembl:ENSP00000390265|ensembl:ENSP00000410513 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:idhc_human(display_long)|uniprotkb:Cytosolic NADP-isocitrate dehydrogenase(gene name synonym)|uniprotkb:Oxalosuccinate decarboxylase(gene name synonym)|uniprotkb:"NADP(+)-specific ICDH"(gene name synonym)|uniprotkb:IDP(gene name synonym)|uniprotkb:IDH1(gene name)|psi-mi:IDH1(display_short)|uniprotkb:PICD(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005887.2|refseq:NP_001269315.1|refseq:NP_001269316.1|ensembl:ENSG00000138413(gene)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071071"(regulation of phospholipid biosynthetic process)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR004790(Isocitrate dehydrogenase NADP-dependent, eukaryotic)|interpro:IPR019818|interpro:IPR024084|rcsb pdb:1T09|rcsb pdb:1T0L|rcsb pdb:3INM|rcsb pdb:3MAP|rcsb pdb:3MAR|rcsb pdb:3MAS|rcsb pdb:4I3K|go:"GO:0060696"(regulation of phospholipid catabolic process)|rcsb pdb:4I3L|rcsb pdb:4KZO|rcsb pdb:4L03|rcsb pdb:4L04|rcsb pdb:4L06|rcsb pdb:4UMX|rcsb pdb:4UMY|rcsb pdb:4XRX|rcsb pdb:4XS3|go:"GO:0005739"(mitochondrion)|go:"GO:0005777"(peroxisome)|go:"GO:0005782"(peroxisomal matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006097"(glyoxylate cycle)|go:"GO:0006099"(tricarboxylic acid cycle)|go:"GO:0006102"(isocitrate metabolic process)|go:"GO:0006103"(2-oxoglutarate metabolic process)|go:"GO:0006739"(NADP metabolic process)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008585"(female gonad development)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|ensembl:ENST00000345146(transcript)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000415913(transcript)|ensembl:ENST00000446179(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004450"("isocitrate dehydrogenase (NADP+) activity")|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0048545"(response to steroid hormone)|go:"GO:0050661"(NADP binding)|go:"GO:0051287"(NAD binding)|rcsb pdb:5DE1|rcsb pdb:5GIR|rcsb pdb:5K10|rcsb pdb:5K11|rcsb pdb:5L57|rcsb pdb:5L58|rcsb pdb:5LGE|rcsb pdb:5SUN|rcsb pdb:5SVF|rcsb pdb:5TQH|rcsb pdb:5YFM|rcsb pdb:5YFN|rcsb pdb:6ADG|rcsb pdb:6B0Z|rcsb pdb:6BKX|rcsb pdb:6BKY|rcsb pdb:6BKZ|rcsb pdb:6BL0|rcsb pdb:6BL1|rcsb pdb:6BL2|rcsb pdb:6IO0|rcsb pdb:6VEI|rcsb pdb:6VG0|reactome:R-HSA-389542|reactome:R-HSA-6798695|reactome:R-HSA-2978092|rcsb pdb:6O2Y|rcsb pdb:6O2Z|rcsb pdb:6PAY|rcsb pdb:6Q6F|rcsb pdb:6U4J|reactome:R-HSA-9033241|dip:DIP-59311N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RFBziMEb70PKCzUCJm2jd40y44M9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:A0MZ66 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-308778|uniprotkb:A8MYU7|uniprotkb:B3KRD3|uniprotkb:B3KRH2|uniprotkb:B3KTE0|uniprotkb:B3KTJ7|uniprotkb:B3KTJ8|uniprotkb:B4E3U1|uniprotkb:Q68DG1|uniprotkb:Q6PIM5|uniprotkb:Q9NUV0|intact:EBI-1057684|uniprotkb:Q9HCH4|ensembl:ENSP00000347532|uniprotkb:B7Z7Z9 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:shot1_human(display_long)|uniprotkb:SHTN1(gene name)|psi-mi:SHTN1(display_short)|uniprotkb:KIAA1598(gene name synonym)|uniprotkb:Shootin1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001120683.1|refseq:NP_060800.2|refseq:XP_016871951.1|ensembl:ENSG00000187164(gene)|ensembl:ENST00000355371(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0019894"(kinesin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0031252"(cell leading edge)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0038007"(netrin-activated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0043204"(perikaryon)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|go:"GO:0061163"(endoplasmic reticulum polarization)|go:"GO:0061573"(actin filament bundle retrograde transport)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR024849|reactome:R-HSA-437239|refseq:NP_001245227.1|refseq:NP_001245228.1|refseq:NP_001245229.1|ensembl:ENST00000260777|ensembl:ENSP00000260777|ensembl:ENSP00000347532|ensembl:ENST00000392901|ensembl:ENSP00000376635|ensembl:ENST00000392903|ensembl:ENSP00000376636|ensembl:ENST00000615301|ensembl:ENSP00000480109 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:dQ89YPXx+jJMJjl6/Dk3AMLWtVQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P18031 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-968788|ensembl:ENSP00000360683|uniprotkb:Q5TGD8|uniprotkb:Q9BQV9|uniprotkb:Q9NQQ4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ptn1_human(display_long)|uniprotkb:PTPN1(gene name)|psi-mi:PTPN1(display_short)|uniprotkb:PTP1B(gene name synonym)|uniprotkb:Protein-tyrosine phosphatase 1B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000196396(gene)|ensembl:ENST00000371621(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006470"(protein dephosphorylation)|go:"GO:0008270"(zinc ion binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0009968"(negative regulation of signal transduction)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030061"(mitochondrial crista)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033157"(regulation of intracellular protein transport)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035335"(peptidyl-tyrosine dephosphorylation)|go:"GO:0035791"(platelet-derived growth factor receptor-beta signaling pathway)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060338"(regulation of type I interferon-mediated signaling pathway)|go:"GO:0060397"(growth hormone receptor signaling pathway via JAK-STAT)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0097443"(sorting endosome)|go:"GO:0098554"(cytoplasmic side of endoplasmic reticulum membrane)|go:"GO:1902202"(regulation of hepatocyte growth factor receptor signaling pathway)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:0061098"(positive regulation of protein tyrosine kinase activity)|go:"GO:1990264"(peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity)|go:"GO:2000646"(positive regulation of receptor catabolic process)|interpro:IPR000242(Protein-tyrosine phosphatase, receptor/non-receptor type)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR003595(Protein-tyrosine phosphatase, catalytic)|interpro:IPR012265(Protein-tyrosine phosphatase, non-receptor type-1, -2)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR029021|mint:P18031|rcsb pdb:1A5Y|rcsb pdb:1BZC|rcsb pdb:1BZH|rcsb pdb:1BZJ|rcsb pdb:1C83|rcsb pdb:1C84|rcsb pdb:1C85|rcsb pdb:1C86|rcsb pdb:1C87|rcsb pdb:1C88|rcsb pdb:1ECV|rcsb pdb:1EEN|rcsb pdb:1EEO|rcsb pdb:1G1F|rcsb pdb:1AAX|rcsb pdb:1G1G|rcsb pdb:1G1H|rcsb pdb:1G7F|rcsb pdb:1G7G|rcsb pdb:1GFY|rcsb pdb:1I57|rcsb pdb:1JF7|rcsb pdb:5QFV|rcsb pdb:5QFW|rcsb pdb:5QFX|rcsb pdb:5QFY|rcsb pdb:5QFZ|rcsb pdb:5QG0|rcsb pdb:5QG1|rcsb pdb:5QG2|rcsb pdb:5QG3|rcsb pdb:5QG4|rcsb pdb:5QG5|rcsb pdb:5QG6|rcsb pdb:5QG7|rcsb pdb:5QG8|rcsb pdb:5QG9|rcsb pdb:5QGA|rcsb pdb:5QGB|rcsb pdb:5QGC|rcsb pdb:5QGD|rcsb pdb:5QGE|rcsb pdb:5QGF|rcsb pdb:5T19|rcsb pdb:6B8E|rcsb pdb:6B8T|rcsb pdb:6B8X|rcsb pdb:6B8Z|rcsb pdb:6B90|rcsb pdb:6B95|rcsb pdb:6BAI|rcsb pdb:6CWU|rcsb pdb:6CWV|rcsb pdb:6NTP|rcsb pdb:6OL4|rcsb pdb:6OLQ|rcsb pdb:6OLV|rcsb pdb:1KAK|rcsb pdb:1KAV|rcsb pdb:1L8G|rcsb pdb:1LQF|rcsb pdb:1NL9|rcsb pdb:1NNY|rcsb pdb:1NO6|rcsb pdb:1NWE|rcsb pdb:1NWL|rcsb pdb:1NZ7|rcsb pdb:1OEM|rcsb pdb:1OEO|rcsb pdb:1OES|rcsb pdb:1OET|rcsb pdb:1OEU|rcsb pdb:1OEV|rcsb pdb:1ONY|rcsb pdb:1ONZ|rcsb pdb:1PA1|rcsb pdb:1PH0|rcsb pdb:1PTT|rcsb pdb:1PTU|rcsb pdb:1PTV|rcsb pdb:1PTY|rcsb pdb:1PXH|rcsb pdb:1PYN|rcsb pdb:1Q1M|rcsb pdb:1Q6J|rcsb pdb:1Q6M|rcsb pdb:1Q6N|rcsb pdb:1Q6P|rcsb pdb:1Q6S|rcsb pdb:1Q6T|rcsb pdb:1QXK|rcsb pdb:1SUG|rcsb pdb:1T48|rcsb pdb:1T49|rcsb pdb:1T4J|rcsb pdb:1WAX|rcsb pdb:1XBO|rcsb pdb:2AZR|rcsb pdb:2B07|rcsb pdb:2B4S|rcsb pdb:2BGD|rcsb pdb:2NT7|rcsb pdb:2BGE|rcsb pdb:2CM2|rcsb pdb:2NTA|rcsb pdb:2CM3|rcsb pdb:2CM7|rcsb pdb:2QBP|rcsb pdb:2CM8|rcsb pdb:2CMA|rcsb pdb:2QBQ|rcsb pdb:2QBR|rcsb pdb:2CMB|rcsb pdb:2CMC|rcsb pdb:2CNE|rcsb pdb:2QBS|rcsb pdb:2CNF|rcsb pdb:2CNG|rcsb pdb:2CNH|rcsb pdb:2CNI|rcsb pdb:2F6F|rcsb pdb:2F6T|rcsb pdb:2VEU|rcsb pdb:2F6V|rcsb pdb:2F6W|rcsb pdb:2F6Y|rcsb pdb:2VEV|rcsb pdb:2VEW|rcsb pdb:2VEX|rcsb pdb:2VEY|rcsb pdb:2F6Z|rcsb pdb:2ZMM|rcsb pdb:2F70|rcsb pdb:2F71|rcsb pdb:2ZN7|rcsb pdb:3A5J|rcsb pdb:2FJM|rcsb pdb:2FJN|rcsb pdb:2H4G|rcsb pdb:2H4K|rcsb pdb:2HB1|rcsb pdb:2HNP|rcsb pdb:2HNQ|rcsb pdb:3A5K|rcsb pdb:3CWE|rcsb pdb:6OMY|rcsb pdb:3D9C|rcsb pdb:3EAX|rcsb pdb:4QAP|rcsb pdb:4QBE|rcsb pdb:3EB1|rcsb pdb:4QBW|rcsb pdb:4Y14|rcsb pdb:4ZRT|rcsb pdb:5K9V|rcsb pdb:5K9W|rcsb pdb:5KA0|rcsb pdb:5KA1|rcsb pdb:5KA2|rcsb pdb:5KA3|rcsb pdb:5KA4|rcsb pdb:5KA7|rcsb pdb:5KA8|rcsb pdb:5KA9|rcsb pdb:5KAA|rcsb pdb:5KAB|rcsb pdb:5KAC|rcsb pdb:5KAD|rcsb pdb:5QDE|rcsb pdb:5QDF|rcsb pdb:5QDG|rcsb pdb:5QDH|rcsb pdb:5QDI|rcsb pdb:5QDJ|rcsb pdb:5QDK|rcsb pdb:5QDL|rcsb pdb:5QDM|rcsb pdb:5QDN|rcsb pdb:3EU0|rcsb pdb:3I7Z|rcsb pdb:3I80|rcsb pdb:3QKP|rcsb pdb:3QKQ|rcsb pdb:3SME|rcsb pdb:3ZMP|rcsb pdb:3ZMQ|rcsb pdb:3ZV2|rcsb pdb:4BJO|rcsb pdb:4I8N|rcsb pdb:4QAH|rcsb pdb:5QDO|rcsb pdb:5QDP|rcsb pdb:5QDQ|rcsb pdb:5QDR|rcsb pdb:5QDS|rcsb pdb:6PG0|rcsb pdb:6PGT|rcsb pdb:6PHA|rcsb pdb:6PHS|rcsb pdb:6PM8|rcsb pdb:6W30|rcsb pdb:7KEN|rcsb pdb:7L0C|rcsb pdb:7L0H|rcsb pdb:7LFO|rcsb pdb:7MM1|reactome:R-HSA-354192|reactome:R-HSA-6807004|reactome:R-HSA-877312|reactome:R-HSA-8849472|reactome:R-HSA-9022699|reactome:R-HSA-912694|reactome:R-HSA-982772|rcsb pdb:6PFW|rcsb pdb:5QDW|rcsb pdb:5QDX|rcsb pdb:5QDY|rcsb pdb:5QDZ|rcsb pdb:5QE0|rcsb pdb:5QE1|rcsb pdb:5QDT|rcsb pdb:5QDU|rcsb pdb:5QE2|rcsb pdb:5QE3|rcsb pdb:5QE4|rcsb pdb:5QE5|rcsb pdb:5QE6|rcsb pdb:5QE7|rcsb pdb:5QE8|rcsb pdb:5QE9|rcsb pdb:5QEA|rcsb pdb:5QEB|rcsb pdb:5QEC|rcsb pdb:5QED|rcsb pdb:5QEE|rcsb pdb:5QEF|rcsb pdb:5QEG|rcsb pdb:5QEH|rcsb pdb:5QEI|rcsb pdb:5QEJ|rcsb pdb:5QDV|rcsb pdb:5QEK|rcsb pdb:5QEL|rcsb pdb:5QEM|rcsb pdb:5QEN|rcsb pdb:5QEO|rcsb pdb:5QEP|rcsb pdb:5QEQ|rcsb pdb:5QER|rcsb pdb:5QES|rcsb pdb:5QET|rcsb pdb:5QEU|rcsb pdb:5QEV|rcsb pdb:5QEW|rcsb pdb:5QEX|rcsb pdb:5QEY|rcsb pdb:5QEZ|rcsb pdb:5QF0|rcsb pdb:5QF1|rcsb pdb:5QF2|rcsb pdb:5QF3|rcsb pdb:5QF4|rcsb pdb:5QF5|rcsb pdb:5QF6|rcsb pdb:5QF7|rcsb pdb:5QF8|rcsb pdb:5QF9|rcsb pdb:5QFA|rcsb pdb:5QFB|rcsb pdb:5QFC|rcsb pdb:5QFD|rcsb pdb:5QFE|rcsb pdb:5QFF|rcsb pdb:5QFG|rcsb pdb:5QFH|rcsb pdb:5QFI|rcsb pdb:5QFJ|rcsb pdb:5QFK|rcsb pdb:5QFL|rcsb pdb:5QFM|rcsb pdb:5QFN|rcsb pdb:5QFO|rcsb pdb:5QFP|rcsb pdb:5QFQ|rcsb pdb:5QFR|rcsb pdb:5QFS|rcsb pdb:5QFT|rcsb pdb:5QFU|refseq:NP_001265547.1|refseq:NP_002818.1|dip:DIP-38014N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yz+WjBWu7IXrpAfeMUJ2s0e0ACM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6FI81 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-750511|uniprotkb:O75206|uniprotkb:O75207|uniprotkb:Q9H0W1|uniprotkb:Q9P1L7|uniprotkb:A8K8B6|ensembl:ENSP00000377914 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cpin1_human(display_long)|uniprotkb:Cytokine-induced apoptosis inhibitor 1(gene name synonym)|uniprotkb:CIAPIN1(gene name)|psi-mi:CIAPIN1(display_short)|uniprotkb:PRO0915(orf name)|uniprotkb:CUA001(orf name)|uniprotkb:Fe-S cluster assembly protein DRE2 homolog(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_064709.2|refseq:NP_001295276.1|refseq:NP_001295287.1|dip:DIP-61697N|go:"GO:0006915"(apoptotic process)|go:"GO:0008168"(methyltransferase activity)|go:"GO:0009055"(electron transfer activity)|go:"GO:0016226"(iron-sulfur cluster assembly)|go:"GO:0030097"(hemopoiesis)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0005758"(mitochondrial intermembrane space)|go:"GO:0046872"(metal ion binding)|go:"GO:0051537"(2 iron, 2 sulfur cluster binding)|go:"GO:0051539"(4 iron, 4 sulfur cluster binding)|interpro:IPR007785(Protein of unknown function DUF689)|interpro:IPR013216(Methyltransferase type 11)|interpro:IPR029063|rcsb pdb:2LD4|rcsb pdb:2YUI|rcsb pdb:4M7R|reactome:R-HSA-2564830|ensembl:ENSG00000005194(gene)|ensembl:ENST00000394391(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:80r/MAg7g8AcGJc7SGHsjE5aWiA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N392 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-372814|uniprotkb:E1P575|uniprotkb:Q58EZ3|uniprotkb:Q6P679|uniprotkb:Q6PJD7|uniprotkb:Q96S64|intact:EBI-28984395|ensembl:ENSP00000357131 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rhg18_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 18(gene name synonym)|uniprotkb:MacGAP(gene name synonym)|uniprotkb:ARHGAP18(gene name)|psi-mi:ARHGAP18(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_277050.2|ensembl:ENSP00000357131|ensembl:ENSG00000146376(gene)|ensembl:ENST00000368149(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016607"(nuclear speck)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:2000145"(regulation of cell motility) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:24F0Swg/Ye/UfWPt8fJcO+q0nkc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UH65 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-310749|uniprotkb:O75135|uniprotkb:Q7LCY6|uniprotkb:Q9P061|uniprotkb:Q9P0Z8|uniprotkb:D3DQV1|ensembl:ENSP00000315630 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:swp70_human(display_long)|uniprotkb:KIAA0640(gene name synonym)|uniprotkb:SWAP70(gene name)|psi-mi:SWAP70(display_short)|uniprotkb:HSPC321(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055870.2|refseq:NP_001284643.1|go:"GO:0060754"(positive regulation of mast cell chemotaxis)|go:"GO:1902309"(negative regulation of peptidyl-serine dephosphorylation)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:2DN6|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|ensembl:ENSG00000133789(gene)|ensembl:ENST00000318950(transcript)|go:"GO:0003677"(DNA binding)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007204"(positive regulation of cytosolic calcium ion concentration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033633"(negative regulation of cell-cell adhesion mediated by integrin)|go:"GO:0045190"(isotype switching)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GU1JyBHhrTRPDnzRBSIJeP8d4ZE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P60228 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-347740|uniprotkb:O43902|uniprotkb:Q64058|uniprotkb:Q64059|uniprotkb:Q64252|uniprotkb:Q8WVK4|intact:EBI-1237448|uniprotkb:Q6FG33|ensembl:ENSP00000220849 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:eif3e_human(display_long)|uniprotkb:EIF3E(gene name)|psi-mi:EIF3E(display_short)|uniprotkb:INT6(gene name synonym)|uniprotkb:EIF3S6(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 3 subunit 6(gene name synonym)|uniprotkb:eIF-3 p48(gene name synonym)|uniprotkb:Viral integration site protein INT-6 homolog(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001559.1|ensembl:ENSG00000104408(gene)|ensembl:ENST00000220849(transcript)|dip:DIP-32691N|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005852"(eukaryotic translation initiation factor 3 complex)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016020"(membrane)|go:"GO:0016282"(eukaryotic 43S preinitiation complex)|go:"GO:0016605"(PML body)|go:"GO:0033290"(eukaryotic 48S preinitiation complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071540"(eukaryotic translation initiation factor 3 complex, eIF3e)|go:"GO:1902416"(positive regulation of mRNA binding)|interpro:IPR000717(Proteasome component region PCI)|interpro:IPR016650(Translation initiation factor 3, subunit 6, eukaryotic)|interpro:IPR019010|interpro:IPR036390|mint:P60228|rcsb pdb:3J8B|rcsb pdb:3J8C|rcsb pdb:6FEC|rcsb pdb:6YBD|rcsb pdb:6ZMW|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZVJ|rcsb pdb:7A09|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:s09LicCa0mb9WwO7esZvVdvUonY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9HC38 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1049764|uniprotkb:Q96B89|uniprotkb:Q9H3J8|uniprotkb:Q9HC37|uniprotkb:Q9NVN1|uniprotkb:D3DTG9|uniprotkb:D3DTH1|ensembl:ENSP00000301328 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:glod4_human(display_long)|uniprotkb:GLOD4(gene name)|psi-mi:GLOD4(display_short)|uniprotkb:C17orf25(gene name synonym)|uniprotkb:CGI-150(orf name)|uniprotkb:My027(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_057164.3|ensembl:ENSG00000167699(gene)|ensembl:ENST00000301328(transcript)|go:"GO:0005739"(mitochondrion)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR029068|interpro:IPR037523|interpro:IPR043193|mint:Q9HC38|rcsb pdb:3ZI1|interpro:IPR043194 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0Xu9EPSkmX9t8j0yLaCyBLhKcUs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P19634 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-743635|uniprotkb:Q96EM2|ensembl:ENSP00000263980|uniprotkb:B1ALD6|uniprotkb:D3DPL4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sl9a1_human(display_long)|uniprotkb:"Na(+)/H(+) exchanger 1"(gene name synonym)|uniprotkb:Solute carrier family 9 member 1(gene name synonym)|uniprotkb:"Na(+)/H(+) antiporter, amiloride-sensitive"(gene name synonym)|uniprotkb:APNH(gene name synonym)|uniprotkb:SLC9A1(gene name)|psi-mi:SLC9A1(display_short)|uniprotkb:APNH1(gene name synonym)|uniprotkb:NHE1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003038.2|go:"GO:0009986"(cell surface)|ensembl:ENSG00000090020(gene)|ensembl:ENST00000263980(transcript)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0010447"(response to acidic pH)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010882"(regulation of cardiac muscle contraction by calcium ion signaling)|go:"GO:0014704"(intercalated disc)|go:"GO:0015299"("solute:proton antiporter activity")|go:"GO:0015385"("sodium:proton antiporter activity")|go:"GO:0015386"("potassium:proton antiporter activity")|go:"GO:0006811"(ion transport)|go:"GO:0006883"(cellular sodium ion homeostasis)|go:"GO:0006885"(regulation of pH)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030027"(lamellipodium)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030315"(T-tubule)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0035794"(positive regulation of mitochondrial membrane permeability)|go:"GO:0035994"(response to muscle stretch)|go:"GO:0036376"(sodium ion export across plasma membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045121"(membrane raft)|go:"GO:0045760"(positive regulation of action potential)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0016021"(integral component of membrane)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051259"(protein complex oligomerization)|go:"GO:0051453"(regulation of intracellular pH)|go:"GO:0051492"(regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0051930"(regulation of sensory perception of pain)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070417"(cellular response to cold)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0070997"(neuron death)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071257"(cellular response to electrical stimulus)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071468"(cellular response to acidic pH)|go:"GO:0071805"(potassium ion transmembrane transport)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0086003"(cardiac muscle cell contraction)|go:"GO:0086036"(regulation of cardiac muscle cell membrane potential)|go:"GO:0086040"("sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential")|go:"GO:0086092"(regulation of the force of heart contraction by cardiac conduction)|go:"GO:0090533"(cation-transporting ATPase complex)|go:"GO:0098719"(sodium ion import across plasma membrane)|go:"GO:0098735"(positive regulation of the force of heart contraction)|go:"GO:1902600"(proton transmembrane transport)|go:"GO:1903281"("positive regulation of calcium:sodium antiporter activity")|interpro:IPR001970("Na+/H+ exchanger isoform 1 (NHE1)")|interpro:IPR004709(Sodium/hydrogen exchanger subfamily)|interpro:IPR006153(Sodium/hydrogen exchanger)|interpro:IPR018422|interpro:IPR032103|mint:P19634|rcsb pdb:1Y4E|rcsb pdb:2BEC|rcsb pdb:2E30|rcsb pdb:2HTG|rcsb pdb:2KBV|rcsb pdb:2L0E|rcsb pdb:2MDF|rcsb pdb:2YGG|rcsb pdb:6BJF|rcsb pdb:6NUC|rcsb pdb:6NUF|rcsb pdb:6NUU|rcsb pdb:6ZBI|rcsb pdb:7DSV|rcsb pdb:7DSW|rcsb pdb:7DSX|reactome:R-HSA-2160916|reactome:R-HSA-425986 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:wU1AHJ9CJrDPjiRZk2PhcO1OfDc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P54136 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-355482|uniprotkb:Q9BWA1|uniprotkb:B2RBS9|uniprotkb:Q53GY4|intact:EBI-28985219|ensembl:ENSP00000231572 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:syrc_human(display_long)|uniprotkb:RARS1(gene name)|psi-mi:RARS1(display_short)|uniprotkb:Arginyl-tRNA synthetase(gene name synonym)|uniprotkb:RARS(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002878.2|ensembl:ENSG00000113643(gene)|ensembl:ENST00000231572(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0004814"(arginine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006420"(arginyl-tRNA aminoacylation)|go:"GO:0016020"(membrane)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0034618"(arginine binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001278(Arginyl-tRNA synthetase, class Ic)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR005148(Arginyl tRNA synthetase, class Ic, N-terminal)|interpro:IPR008909(DALR anticodon binding)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR014729(Rossmann-like alpha/beta/alpha sandwich fold)|interpro:IPR035684|interpro:IPR036695|mint:P54136|rcsb pdb:4Q2T|rcsb pdb:4Q2X|rcsb pdb:4Q2Y|rcsb pdb:4R3Z|rcsb pdb:4ZAJ|reactome:R-HSA-2408522|reactome:R-HSA-379716|ensembl:ENSP00000231572 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:oM9gWF1NucjgVjBFm4DcjmnQNCE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q86X29 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1056946|uniprotkb:O00112|uniprotkb:O00426|uniprotkb:Q6ZT80|uniprotkb:Q9UQL3|uniprotkb:E9PHD4|uniprotkb:Q8NBM0|uniprotkb:Q9BT33|uniprotkb:B4DKL4|uniprotkb:A6NDW3|ensembl:ENSP00000354575|ensembl:ENSP00000480821|intact:EBI-10982122 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lsr_human(display_long)|uniprotkb:LSR(gene name)|psi-mi:LSR(display_short)|uniprotkb:LISCH(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_991403.1|refseq:NP_001247418.1|refseq:NP_001247419.1|refseq:NP_057009.3|refseq:NP_991404.1|ensembl:ENSG00000105699(gene)|ensembl:ENST00000361790(transcript)|ensembl:ENST00000621372(transcript)|go:"GO:0001889"(liver development)|go:"GO:0005886"(plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042627"(chylomicron)|go:"GO:0060856"(establishment of blood-brain barrier)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0061689"(tricellular tight junction)|go:"GO:0061833"(protein localization to tricellular tight junction)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904274"(tricellular tight junction assembly)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR008664(LISCH7)|interpro:IPR036179|reactome:R-HSA-8964038|reactome:R-HSA-8964046 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:jCmNdVxzNBHEpWjKNqyq5e6yEjs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5VZ89 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2871535|uniprotkb:Q9NWT3|uniprotkb:A2A3R9|uniprotkb:Q6ZUB3|uniprotkb:Q9NUT1|uniprotkb:A2A3R1|uniprotkb:Q6AI48|uniprotkb:A2A3R2|uniprotkb:Q9H6N4|uniprotkb:Q9NWA5|uniprotkb:A2A3R3|uniprotkb:Q8NCY7|uniprotkb:R4GN35|uniprotkb:R4GNB2|intact:EBI-28974130|ensembl:ENSP00000473565 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:den4c_human(display_long)|uniprotkb:DENND4C(gene name)|psi-mi:DENND4C(display_short)|uniprotkb:C9orf55(gene name synonym)|uniprotkb:C9orf55B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000434457|ensembl:ENSP00000473469|ensembl:ENSP00000473565|refseq:NP_001317569.1|refseq:NP_060395.5|ensembl:ENSG00000137145(gene)|ensembl:ENST00000602925(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0030904"(retromer complex)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032483"(regulation of Rab protein signal transduction)|go:"GO:0032593"(insulin-responsive compartment)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001194(DENN)|interpro:IPR005112(dDENN)|interpro:IPR005113(uDENN)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR023341|interpro:IPR037516|interpro:IPR043153|reactome:R-HSA-8876198 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:kc65D0Vb3SHO6xMWZ1TC25Tp/Nw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P50552 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-748201|uniprotkb:Q6PIZ1|uniprotkb:Q93035|uniprotkb:B2RBT9|intact:EBI-28992147|ensembl:ENSP00000245932 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vasp_human(display_long)|uniprotkb:VASP(gene name)|psi-mi:VASP(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003361.1|ensembl:ENSP00000245932|ensembl:ENSG00000125753(gene)|ensembl:ENST00000245932(transcript)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007411"(axon guidance)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0031527"(filopodium membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000697(EVH1)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014885(VASP tetramerisation)|interpro:IPR017354(Vasodilator-stimulated phosphoprotein)|interpro:IPR034367|interpro:IPR038023|mint:P50552|rcsb pdb:1EGX|rcsb pdb:1JNG|rcsb pdb:1USD|rcsb pdb:1USE|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|reactome:R-HSA-202433|reactome:R-HSA-376176|reactome:R-HSA-446353|dip:DIP-44105N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:G8ONp2lhbQKUCrDKnx8AMIKSNHA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5VZK9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2563775|uniprotkb:Q9NXU7|uniprotkb:Q6ZUH5|uniprotkb:Q6ZW07|ensembl:ENSP00000331983|uniprotkb:B8X1J0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:carl1_human(display_long)|uniprotkb:CARMIL1(gene name)|psi-mi:CARMIL1(display_short)|uniprotkb:CARMIL(gene name synonym)|uniprotkb:CARMIL homolog(gene name synonym)|uniprotkb:Capping protein regulator and myosin 1 linker protein 1(gene name synonym)|uniprotkb:Capping protein, Arp2/3 and myosin-I linker homolog 1(gene name synonym)|uniprotkb:Capping protein, Arp2/3 and myosin-I linker protein 1(gene name synonym)|uniprotkb:LRRC16(gene name synonym)|uniprotkb:LRRC16A(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 16A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060110.4|ensembl:ENSG00000079691(gene)|ensembl:ENST00000329474(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0016607"(nuclear speck)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0044351"(macropinocytosis)|go:"GO:0044354"(macropinosome)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046415"(urate metabolic process)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051638"(barbed-end actin filament uncapping)|go:"GO:0051639"(actin filament network formation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902745"(positive regulation of lamellipodium organization)|go:"GO:2000813"(negative regulation of barbed-end actin filament capping)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029764|interpro:IPR031943|interpro:IPR032675|interpro:IPR041245|rcsb pdb:3LK2|rcsb pdb:3LK3|reactome:R-HSA-983231|dip:DIP-56920N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fTPXRG90Nws44WR+K28ZkDqDBSg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N271 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-18210782|uniprotkb:A8K2V1|uniprotkb:Q2HIX6|uniprotkb:Q8NB84|uniprotkb:Q8TAE2|ensembl:ENSP00000318270|ensembl:ENSP00000318520|ensembl:ENSP00000385716 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:prom2_human(display_long)|uniprotkb:Prominin-like protein 2(gene name synonym)|uniprotkb:UNQ2521/PRO6014(orf name)|uniprotkb:PROM2(gene name)|psi-mi:PROM2(display_short)|uniprotkb:PROML2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001159449.1|refseq:NP_001159450.1|refseq:NP_653308.2|ensembl:ENSG00000155066(gene)|ensembl:ENST00000317620(transcript)|ensembl:ENST00000317668(transcript)|ensembl:ENST00000403131(transcript)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005929"(cilium)|go:"GO:0009986"(cell surface)|go:"GO:0015485"(cholesterol binding)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0031346"(positive regulation of cell projection organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031528"(microvillus membrane)|go:"GO:0042995"(cell projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0044393"(microspike)|go:"GO:0048550"(negative regulation of pinocytosis)|go:"GO:0060170"(ciliary membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071914"(prominosome)|go:"GO:2001287"(negative regulation of caveolin-mediated endocytosis)|interpro:IPR008795(Prominin)|go:"GO:0016324"(apical plasma membrane) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ofGKb4Njg9Mjdj6CRHBYSsdfyMw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y6E0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-740175|uniprotkb:O14840|ensembl:ENSP00000365730|uniprotkb:Q5JV92|intact:EBI-1054809 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stk24_human(display_long)|uniprotkb:STK24(gene name)|psi-mi:STK24(display_short)|uniprotkb:MST3(gene name synonym)|uniprotkb:STK3(gene name synonym)|uniprotkb:STE20-like kinase MST3(gene name synonym)|uniprotkb:Mammalian STE20-like protein kinase 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000102572(gene)|ensembl:ENST00000376547(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0008631"(intrinsic apoptotic signaling pathway in response to oxidative stress)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0045296"(cadherin binding)|refseq:NP_001027467.2|refseq:NP_003567.2|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046872"(metal ion binding)|go:"GO:0048679"(regulation of axon regeneration)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097194"(execution phase of apoptosis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:3A7F|rcsb pdb:3A7G|rcsb pdb:3A7H|rcsb pdb:3A7I|rcsb pdb:3A7J|rcsb pdb:3CKW|rcsb pdb:3CKX|rcsb pdb:3ZHP|rcsb pdb:4O27|rcsb pdb:4QML|rcsb pdb:4QMM|rcsb pdb:4QMN|rcsb pdb:4QMO|rcsb pdb:4QMP|rcsb pdb:4QMQ|rcsb pdb:4QMS|rcsb pdb:4QMT|rcsb pdb:4QMU|rcsb pdb:4QMV|rcsb pdb:4QMW|rcsb pdb:4QMX|rcsb pdb:4QMY|rcsb pdb:4QMZ|rcsb pdb:4QNA|rcsb pdb:4QO9|rcsb pdb:4U8Z|rcsb pdb:4W8D|rcsb pdb:4W8E|rcsb pdb:7B30|rcsb pdb:7B31|rcsb pdb:7B32|rcsb pdb:7B33|rcsb pdb:7B34|rcsb pdb:7B35|reactome:R-HSA-111465|reactome:R-HSA-75153|dip:DIP-40608N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:El6otOj/3rikTQX8EOIz3Eohgsw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NPH2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-720563|intact:EBI-1050340|uniprotkb:Q7Z525|uniprotkb:Q9BT65|uniprotkb:Q9H2Y2|uniprotkb:Q9NSU0|uniprotkb:Q9NVW7|uniprotkb:Q6NXT5|uniprotkb:B3KRT1|uniprotkb:G5E9U0|ensembl:ENSP00000337746 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ino1_human(display_long)|uniprotkb:INO1(gene name synonym)|uniprotkb:ISYNA1(gene name)|psi-mi:ISYNA1(display_short)|uniprotkb:Myo-inositol 1-phosphate synthase A1(gene name synonym)|uniprotkb:Myo-inositol 1-phosphate synthase(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001164409.1|refseq:NP_057452.1|refseq:NP_001240318.1|go:"GO:0006021"(inositol biosynthetic process)|go:"GO:0008654"(phospholipid biosynthetic process)|interpro:IPR002587(Myo-inositol-1-phosphate synthase)|interpro:IPR013021(Myo-inositol-1-phosphate synthase, GAPDH-like)|interpro:IPR036291|reactome:R-HSA-1855183|ensembl:ENSG00000105655(gene)|ensembl:ENST00000338128(transcript)|go:"GO:0004512"(inositol-3-phosphate synthase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:46Ryo/iaI6hmbkuetMsJSyrm3FU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q08378 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-355782|uniprotkb:O43241|uniprotkb:Q6P9C7|uniprotkb:Q86XW3|uniprotkb:Q8TDA9|uniprotkb:Q8WZA3|uniprotkb:A5PKX6|intact:EBI-28985028|ensembl:ENSP00000204726|ensembl:ENSP00000410378 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:goga3_human(display_long)|uniprotkb:GOLGA3(gene name)|psi-mi:GOLGA3(display_short)|uniprotkb:Golgin-160(gene name synonym)|uniprotkb:Golgi complex-associated protein of 170 kDa(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001166028.1|refseq:NP_005886.2|ensembl:ENSP00000204726|ensembl:ENSP00000410378|ensembl:ENST00000456883|ensembl:ENSP00000409303|ensembl:ENST00000545875|ensembl:ENSP00000442603|ensembl:ENSG00000090615(gene)|ensembl:ENST00000204726(transcript)|ensembl:ENST00000450791(transcript)|go:"GO:0045296"(cadherin binding)|go:"GO:0090498"(extrinsic component of Golgi membrane)|interpro:IPR033288|mint:Q08378|go:"GO:0000139"(Golgi membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9696270|go:"GO:0005829"(cytosol)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0032580"(Golgi cisterna membrane)|refseq:XP_006719799.1|refseq:XP_006719800.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7AjSzX3sUzfKpZkvdKDM0L//zYM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P22681 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-518228|uniprotkb:A3KMP8|ensembl:ENSP00000264033 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cbl_human(display_long)|uniprotkb:Signal transduction protein CBL(gene name synonym)|uniprotkb:Proto-oncogene c-Cbl(gene name synonym)|uniprotkb:Casitas B-lineage lymphoma proto-oncogene(gene name synonym)|uniprotkb:RING finger protein 55(gene name synonym)|uniprotkb:CBL(gene name)|psi-mi:CBL(display_short)|uniprotkb:CBL2(gene name synonym)|uniprotkb:RNF55(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase CBL(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005179.2|ensembl:ENSP00000264033|dip:DIP-189N|ensembl:ENSG00000110395(gene)|ensembl:ENST00000264033(transcript)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005929"(cilium)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0008584"(male gonad development)|go:"GO:0010332"(response to gamma radiation)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0014823"(response to activity)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0016600"(flotillin complex)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0030426"(growth cone)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0033574"(response to testosterone)|go:"GO:0035635"(entry of bacterium into host cell)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042594"(response to starvation)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043303"(mast cell degranulation)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045742"(positive regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0046677"(response to antibiotic)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:0070997"(neuron death)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090650"(cellular response to oxygen-glucose deprivation)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2000583"(regulation of platelet-derived growth factor receptor-alpha signaling pathway)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR003153(Adaptor protein Cbl, N-terminal helical)|interpro:IPR009060(UBA-like)|interpro:IPR011992(EF-Hand type)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR014741(Adaptor protein Cbl, EF hand-like)|interpro:IPR014742(Adaptor protein Cbl, SH2-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017907|interpro:IPR024159|interpro:IPR024162|interpro:IPR036537|interpro:IPR036860|interpro:IPR039520|mint:P22681|rcsb pdb:1B47|rcsb pdb:1FBV|rcsb pdb:1YVH|rcsb pdb:2CBL|rcsb pdb:2JUJ|rcsb pdb:2K4D|rcsb pdb:2OO9|rcsb pdb:2Y1M|rcsb pdb:2Y1N|rcsb pdb:3BUM|rcsb pdb:3BUN|rcsb pdb:3BUO|rcsb pdb:3BUW|rcsb pdb:3BUX|rcsb pdb:3OB1|rcsb pdb:3OB2|rcsb pdb:3PLF|rcsb pdb:4A49|rcsb pdb:4A4B|rcsb pdb:4A4C|rcsb pdb:4GPL|rcsb pdb:5HKW|rcsb pdb:5HKX|rcsb pdb:5HKY|rcsb pdb:5HKZ|rcsb pdb:5HL0|rcsb pdb:5J3X|rcsb pdb:5O76|rcsb pdb:6O02|rcsb pdb:6O03|rcsb pdb:6XAR|reactome:R-HSA-1059683|reactome:R-HSA-1236382|reactome:R-HSA-1295596|reactome:R-HSA-1433559|reactome:R-HSA-182971|reactome:R-HSA-2173789|reactome:R-HSA-5637810|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-6807004|reactome:R-HSA-8849469|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|reactome:R-HSA-912631|reactome:R-HSA-9706369|reactome:R-HSA-9706377 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WPXFRmBKHEANKUlN/OYsuyAe9a09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O14639 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-487024|uniprotkb:A6NI16|uniprotkb:Q5T6N3|uniprotkb:Q5JVV1|uniprotkb:Q15039|uniprotkb:Q68CQ9|uniprotkb:Q9BUP1|uniprotkb:Q5T6N5|uniprotkb:B3KVH2|uniprotkb:Q5T6N2|uniprotkb:A6NJ06|uniprotkb:A8MXA9|uniprotkb:Q5JVV2|ensembl:ENSP00000277895 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ablm1_human(display_long)|uniprotkb:Actin-binding LIM protein family member 1(gene name synonym)|uniprotkb:Actin-binding double zinc finger protein(gene name synonym)|uniprotkb:Limatin(gene name synonym)|uniprotkb:ABLIM1(gene name)|psi-mi:ABLIM1(display_short)|uniprotkb:ABLIM(gene name synonym)|uniprotkb:KIAA0059(gene name synonym)|uniprotkb:LIMAB1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001003407.1|refseq:NP_002304.3|refseq:NP_006711.3|ensembl:ENSG00000099204(gene)|ensembl:ENST00000277895(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007601"(visual perception)|go:"GO:0009887"(animal organ morphogenesis)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028448|interpro:IPR032402|interpro:IPR036886|mint:O14639|reactome:R-HSA-418885|go:"GO:0030032"(lamellipodium assembly)|refseq:NP_001309811.1|refseq:NP_001309821.1|refseq:NP_001309822.1|refseq:NP_001309825.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Dsx3GrmdlsYUmQvuW59NfYF7MJg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BY44 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1776615|uniprotkb:Q5QTR2|uniprotkb:Q7Z4E9|uniprotkb:Q8NFM1|uniprotkb:Q96EW9|uniprotkb:Q96K81|uniprotkb:A8MPS6|uniprotkb:B4DF96|uniprotkb:B4DQ14|uniprotkb:D3DNI9|ensembl:ENSP00000417229 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:eif2a_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short)|uniprotkb:CDA02(orf name)|uniprotkb:MSTP004(orf name)|uniprotkb:MSTP089(orf name)|uniprotkb:65 kDa eukaryotic translation initiation factor 2A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_114414.2|refseq:NP_001305972.1|refseq:NP_001305973.1|refseq:NP_001305974.1|refseq:NP_001305975.1|dip:DIP-40272N|ensembl:ENSG00000144895(gene)|ensembl:ENST00000460851(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9BY44 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:67hYEz0CrhoQ7SfXxZdOWqKzil89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96A49 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10770179|uniprotkb:Q68CP1|uniprotkb:Q96C60|uniprotkb:Q96JQ6|uniprotkb:Q96T20|ensembl:ENSP00000369500 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:syap1_human(display_long)|uniprotkb:SYAP1(gene name)|psi-mi:SYAP1(display_short)|uniprotkb:BSD domain-containing signal transducer and Akt interactor protein(gene name synonym)|uniprotkb:PRO3113(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_116185.2|go:"GO:0030426"(growth cone)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0038203"(TORC2 signaling)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045600"(positive regulation of fat cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|interpro:IPR005607(BSD)|interpro:IPR035925|rcsb pdb:1X3A|ensembl:ENSG00000169895(gene)|ensembl:ENST00000380155(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0030154"(cell differentiation)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+gHfLl7YaR8geuci2/cAYP8CiKA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96NY8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4314784|uniprotkb:Q96K15|uniprotkb:B4DQW3|ensembl:ENSP00000356991 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nect4_human(display_long)|uniprotkb:NECTIN4(gene name)|psi-mi:NECTIN4(display_short)|uniprotkb:Ig superfamily receptor LNIR(gene name synonym)|uniprotkb:LNIR(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 4(gene name synonym)|uniprotkb:PRR4(gene name synonym)|uniprotkb:PVRL4(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_112178.2|ensembl:ENSG00000143217(gene)|ensembl:ENST00000368012(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033320|interpro:IPR036179|rcsb pdb:4FRW|rcsb pdb:4GJT|rcsb pdb:4JJH|reactome:R-HSA-418990|reactome:R-HSA-420597|dip:DIP-41492N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xh33OK0Z4RsYD8uJZYbmnGfs/TQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95067 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-375024|uniprotkb:Q6FI99|uniprotkb:B3KM93|ensembl:ENSP00000288207 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ccnb2_human(display_long)|uniprotkb:CCNB2(gene name)|psi-mi:CCNB2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004692.1|ensembl:ENSG00000157456(gene)|ensembl:ENST00000288207(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0000307"(cyclin-dependent protein kinase holoenzyme complex)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007057"(spindle assembly involved in female meiosis I)|go:"GO:0008315"(G2/MI transition of meiotic cell cycle)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016538"(cyclin-dependent protein serine/threonine kinase regulator activity)|go:"GO:0040008"(regulation of growth)|go:"GO:0043029"(T cell homeostasis)|go:"GO:0044772"(mitotic cell cycle phase transition)|go:"GO:0045296"(cadherin binding)|go:"GO:0048538"(thymus development)|go:"GO:0051301"(cell division)|interpro:IPR004367(Cyclin, C-terminal)|interpro:IPR006671(Cyclin, N-terminal)|interpro:IPR013763(Cyclin-related)|interpro:IPR036915|interpro:IPR039361|mint:O95067|reactome:R-HSA-156711|reactome:R-HSA-162658|reactome:R-HSA-2500257|reactome:R-HSA-2514853|reactome:R-HSA-2565942|reactome:R-HSA-2980767|reactome:R-HSA-2995383|reactome:R-HSA-3301854|reactome:R-HSA-69273|reactome:R-HSA-69478|reactome:R-HSA-8852276|dip:DIP-31730N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7ztz22HOOgNq/6KO1iXhGT3tb+A9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P42566 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-396684|uniprotkb:B2R8J7|uniprotkb:Q5SRH4|uniprotkb:D3DPJ2|intact:EBI-28966731|ensembl:ENSP00000360798 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:eps15_human(display_long)|uniprotkb:EPS15(gene name)|psi-mi:EPS15(display_short)|uniprotkb:AF1P(gene name synonym)|uniprotkb:Protein AF-1p(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001153441.1|refseq:NP_001972.1|ensembl:ENSP00000360798|ensembl:ENSG00000085832(gene)|ensembl:ENST00000371733(transcript)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006895"(Golgi to endosome transport)|go:"GO:0006897"(endocytosis)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015031"(protein transport)|go:"GO:0016020"(membrane)|go:"GO:0016050"(vesicle organization)|go:"GO:0016197"(endosomal transport)|go:"GO:0016235"(aggresome)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0031593"(polyubiquitin modification-dependent protein binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0098794"(postsynapse)|go:"GO:0098884"(postsynaptic neurotransmitter receptor internalization)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:P42566|rcsb pdb:1C07|rcsb pdb:1EH2|rcsb pdb:1F8H|rcsb pdb:1FF1|rcsb pdb:2IV9|rcsb pdb:2JXC|rcsb pdb:4RH5|rcsb pdb:4RH9|rcsb pdb:4RHG|rcsb pdb:4S0G|rcsb pdb:5AWT|rcsb pdb:5AWU|rcsb pdb:5JP2|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360|go:"GO:0019065"(receptor-mediated endocytosis of virus by host cell)|dip:DIP-33064N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:8wPyg852YodFBHvQ0Rocp8DQvxs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P46060 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-396091|uniprotkb:Q96JJ2|ensembl:ENSP00000401470|ensembl:ENSP00000348577|ensembl:ENSP00000385866 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ragp1_human(display_long)|uniprotkb:RANGAP1(gene name)|psi-mi:RANGAP1(display_short)|uniprotkb:KIAA1835(gene name synonym)|uniprotkb:SD(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002874.1|ensembl:ENST00000356244(transcript)|ensembl:ENST00000405486(transcript)|ensembl:ENST00000455915(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0003723"(RNA binding)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0016235"(aggresome)|go:"GO:0030425"(dendrite)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|refseq:XP_011528596.1|refseq:XP_011528597.1|refseq:NP_001304859.1|go:"GO:0031965"(nuclear membrane)|interpro:IPR009109(Ran-GTPase activating protein 1, C-terminal)|interpro:IPR032675|interpro:IPR036720|mint:P46060|rcsb pdb:1Z5S|rcsb pdb:2GRN|rcsb pdb:2GRO|rcsb pdb:2GRP|rcsb pdb:2GRQ|rcsb pdb:2GRR|rcsb pdb:2IO2|rcsb pdb:2IO3|rcsb pdb:2IY0|rcsb pdb:3UIN|rcsb pdb:3UIO|rcsb pdb:3UIP|rcsb pdb:5D2M|reactome:R-HSA-141444|reactome:R-HSA-165054|reactome:R-HSA-2467813|interpro:IPR001611(Leucine-rich repeat)|reactome:R-HSA-2500257|reactome:R-HSA-3108232|go:"GO:0044614"(nuclear pore cytoplasmic filaments)|go:"GO:0045296"(cadherin binding)|go:"GO:0046826"(negative regulation of protein export from nucleus)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048678"(response to axon injury)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1904115"(axon cytoplasm)|go:"GO:1904117"(cellular response to vasopressin)|go:"GO:1990723"(cytoplasmic periphery of the nuclear pore complex)|go:"GO:0043231"(intracellular membrane-bounded organelle)|ensembl:ENSG00000100401(gene)|refseq:XP_006724352.1|reactome:R-HSA-4615885|refseq:NP_001265580.1|reactome:R-HSA-68877|reactome:R-HSA-9615933|reactome:R-HSA-9648025|reactome:R-HSA-5663220|refseq:XP_016884382.1|refseq:XP_016884383.1|refseq:XP_016884384.1|refseq:XP_016884385.1|refseq:XP_016884386.1|dip:DIP-29079N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:pUpd+7p5CeAKaRGLo/bXTeiwjiM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O76039 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1752465|uniprotkb:Q14198|uniprotkb:Q5H985|uniprotkb:Q8IYC7|uniprotkb:Q9UJL6|ensembl:ENSP00000485244|uniprotkb:G9B9X4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cdkl5_human(display_long)|uniprotkb:CDKL5(gene name)|psi-mi:CDKL5(display_short)|uniprotkb:STK9(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 9(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000008086(gene)|ensembl:ENST00000623535(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004693"(cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0016301"(kinase activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032839"(dendrite cytoplasm)|refseq:NP_001310218.1|refseq:NP_001032420.1|refseq:NP_003150.1|go:"GO:0036064"(ciliary basal body)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044294"(dendritic growth cone)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050775"(positive regulation of dendrite morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0097542"(ciliary tip)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1902017"(regulation of cilium assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|rcsb pdb:4BGQ - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:jFecXdpQE+yBwqpPPU0ZGcnOheI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9HB21 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2652984|uniprotkb:Q9BVK0|uniprotkb:D3DRE2|uniprotkb:B3KQ55|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkha1_human(display_long)|uniprotkb:PLEKHA1(gene name)|psi-mi:PLEKHA1(display_short)|uniprotkb:TAPP1(gene name synonym)|uniprotkb:Tandem PH domain-containing protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001001974.1|refseq:NP_001182537.1|refseq:NP_067635.2|refseq:NP_001317107.1|refseq:XP_016871969.1|refseq:XP_016871970.1|refseq:XP_016871971.1|refseq:XP_016871979.1|refseq:XP_016871980.1|ensembl:ENSG00000107679(gene)|ensembl:ENST00000368990(transcript)|ensembl:ENST00000392799(transcript)|ensembl:ENST00000433307(transcript)|go:"GO:0001553"(luteinization)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008209"(androgen metabolic process)|go:"GO:0008210"(estrogen metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033327"(Leydig cell differentiation)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0048008"(platelet-derived growth factor receptor signaling pathway)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0050853"(B cell receptor signaling pathway)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060021"(roof of mouth development)|go:"GO:0060325"(face morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|reactome:R-HSA-1660499|rcsb pdb:1EAZ|refseq:XP_005270073.1|refseq:XP_005270078.1|ensembl:ENST00000368988|ensembl:ENSP00000357984|ensembl:ENSP00000357986|ensembl:ENSP00000376547|ensembl:ENSP00000394416 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:a4aD7YitZrTeGt2rr8x7+nikTlg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q08379 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-618309|intact:EBI-28970132|ensembl:ENSP00000478799|uniprotkb:Q6GRM9|uniprotkb:Q9BRB0|uniprotkb:Q9NYF9|uniprotkb:A0A0C4DGS5|intact:EBI-11522202 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:goga2_human(display_long)|uniprotkb:GOLGA2(gene name)|psi-mi:GOLGA2(display_short)|uniprotkb:130 kDa cis-Golgi matrix protein(gene name synonym)|uniprotkb:GM130 autoantigen(gene name synonym)|uniprotkb:Golgin-95(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000167110(gene)|ensembl:ENST00000611957(transcript)|go:"GO:0000137"(Golgi cis cisterna)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000922"(spindle pole)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0005874"(microtubule)|go:"GO:0006486"(protein glycosylation)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007020"(microtubule nucleation)|go:"GO:0007030"(Golgi organization)|go:"GO:0007098"(centrosome cycle)|go:"GO:0008017"(microtubule binding)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0015031"(protein transport)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030134"(COPII-coated ER to Golgi transport vesicle)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032580"(Golgi cisterna membrane)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0060050"(positive regulation of protein glycosylation)|go:"GO:0061676"(importin-alpha family protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:0090161"(Golgi ribbon formation)|go:"GO:0090166"(Golgi disassembly)|go:"GO:0090306"(meiotic spindle assembly)|go:"GO:0090307"(mitotic spindle assembly)|interpro:IPR024858|interpro:IPR043937|interpro:IPR043976|mint:Q08379|rcsb pdb:4REY|rcsb pdb:6IW8|rcsb pdb:6IWA|rcsb pdb:6K06|reactome:R-HSA-162658|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-8862803|refseq:NP_004477.3|ensembl:ENSP00000478799|dip:DIP-34271N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:vIlRg4sJ2oBiARNnyerGMaVr5ZU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P02794 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-713259|uniprotkb:Q3KRA8|uniprotkb:Q3SWW1|ensembl:ENSP00000273550|ensembl:ENSP00000484477|uniprotkb:B3KNR5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:frih_human(display_long)|uniprotkb:Cell proliferation-inducing gene 15 protein(gene name synonym)|uniprotkb:FTH1(gene name)|psi-mi:FTH1(display_short)|uniprotkb:FTH(gene name synonym)|uniprotkb:FTHL6(gene name synonym)|uniprotkb:PIG15(orf name)|uniprotkb:OK/SW-cl.84(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002023.2|ensembl:ENSG00000167996(gene)|ensembl:ENST00000273550(transcript)|ensembl:ENST00000620041(transcript)|go:"GO:0004322"(ferroxidase activity)|go:"GO:0005506"(iron ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006826"(iron ion transport)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0006880"(intracellular sequestering of iron ion)|go:"GO:0006955"(immune response)|go:"GO:0008043"(intracellular ferritin complex)|go:"GO:0008198"(ferrous iron binding)|go:"GO:0008199"(ferric iron binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0044754"(autolysosome)|mint:P02794|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:1FHA|rcsb pdb:2CEI|rcsb pdb:2CHI|rcsb pdb:2CIH|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001519(Ferritin, N-terminal)|interpro:IPR008331(Ferritin and Dps)|interpro:IPR009040(Ferritin-like)|interpro:IPR009078(Ferritin/ribonucleotide reductase-like)|interpro:IPR012347(Ferritin-related)|interpro:IPR014034(Ferritin, conserved site)|rcsb pdb:2CLU|rcsb pdb:2CN6|rcsb pdb:2CN7|rcsb pdb:2FHA|rcsb pdb:2IU2|rcsb pdb:2Z6M|rcsb pdb:3AJO|rcsb pdb:3AJP|rcsb pdb:3AJQ|rcsb pdb:3ERZ|rcsb pdb:3ES3|rcsb pdb:4DYX|rcsb pdb:4DYY|rcsb pdb:4DYZ|rcsb pdb:4Y08|rcsb pdb:4YKH|rcsb pdb:4ZJK|rcsb pdb:5CMQ|rcsb pdb:5CMR|rcsb pdb:5GN8|rcsb pdb:5GOU|rcsb pdb:5JKK|rcsb pdb:5JKL|rcsb pdb:5JKM|rcsb pdb:5N26|rcsb pdb:5N27|rcsb pdb:5UP7|rcsb pdb:5UP8|rcsb pdb:5UP9|rcsb pdb:5VTD|rcsb pdb:5XB1|rcsb pdb:5YI5|rcsb pdb:5ZND|rcsb pdb:6B8F|rcsb pdb:6B8G|rcsb pdb:4DZ0|rcsb pdb:6FTV|rcsb pdb:6GSR|rcsb pdb:6H5I|rcsb pdb:6H6T|rcsb pdb:6H6U|rcsb pdb:6IPC|rcsb pdb:6IPO|rcsb pdb:6IPP|rcsb pdb:6IPQ|rcsb pdb:6J4A|rcsb pdb:6J7G|rcsb pdb:6JOB|rcsb pdb:6JPS|rcsb pdb:6KE2|rcsb pdb:6KE4|rcsb pdb:4OYN|rcsb pdb:6M52|rcsb pdb:6M54|rcsb pdb:6WYF|rcsb pdb:6WYG|rcsb pdb:6WYH|rcsb pdb:6Z6U|rcsb pdb:6Z9E|rcsb pdb:6Z9F|rcsb pdb:7A6A|rcsb pdb:7A6B|rcsb pdb:7CK8|rcsb pdb:7CK9|rcsb pdb:7JGK|rcsb pdb:7JGL|rcsb pdb:7JGM|rcsb pdb:7JGN|rcsb pdb:7JGO|rcsb pdb:7JGP|rcsb pdb:7JGQ|rcsb pdb:7K26|rcsb pdb:7K3V|rcsb pdb:7K3W|reactome:R-HSA-3000480|reactome:R-HSA-432722|reactome:R-HSA-6798695|reactome:R-HSA-917937|dip:DIP-38301N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:TchHgRpv+inA8BQ5i0OHaa267tQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P52630 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1546963|uniprotkb:Q16430|uniprotkb:Q16431|uniprotkb:Q9UDL4|intact:EBI-10989287|uniprotkb:B4DLC7|uniprotkb:G3V2M6|ensembl:ENSP00000315768 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stat2_human(display_long)|uniprotkb:p113(gene name synonym)|uniprotkb:STAT2(gene name)|psi-mi:STAT2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005410.1|refseq:NP_938146.1|dip:DIP-38511N|ensembl:ENSG00000170581(gene)|ensembl:ENST00000314128(transcript)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0060339"(negative regulation of type I interferon-mediated signaling pathway)|go:"GO:0090140"(regulation of mitochondrial fission)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022756|interpro:IPR035854|interpro:IPR036535|interpro:IPR036860|mint:P52630|rcsb pdb:2KA4|rcsb pdb:6UX2|rcsb pdb:6WCZ|reactome:R-HSA-8854691|reactome:R-HSA-909733|reactome:R-HSA-912694|reactome:R-HSA-9679191 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:uA0lxm5vmrLClQRP7NItd0/u4Ko9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NR12 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350517|uniprotkb:Q14250|uniprotkb:Q5XG82|uniprotkb:Q6NVZ5|uniprotkb:Q96C91|uniprotkb:Q9BXB8|uniprotkb:Q9BXB9|intact:EBI-2556830|ensembl:ENSP00000348099 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pdli7_human(display_long)|uniprotkb:LIM mineralization protein(gene name synonym)|uniprotkb:Protein enigma(gene name synonym)|uniprotkb:PDLIM7(gene name)|psi-mi:PDLIM7(display_short)|uniprotkb:ENIGMA(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_976227.1|refseq:NP_998801.1|refseq:NP_005442.2|ensembl:ENST00000355572|ensembl:ENSP00000347776|ensembl:ENSP00000348099|ensembl:ENST00000359895|ensembl:ENSP00000352964|ensembl:ENST00000393551|ensembl:ENSP00000377182|ensembl:ENST00000486828|ensembl:ENSP00000439157|ensembl:ENST00000493815|ensembl:ENSP00000431236|ensembl:ENSG00000196923(gene)|ensembl:ENST00000355841(transcript)|go:"GO:0001503"(ossification)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007507"(heart development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030154"(cell differentiation)|go:"GO:0031941"(filamentous actin)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR036034|rcsb pdb:2Q3G|reactome:R-HSA-8853659 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XBVF0Y1DFqIYbnt/e/rYqS/m4d09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q12846 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-744942|uniprotkb:Q15525|ensembl:ENSP00000317714|uniprotkb:Q6FHE8|uniprotkb:A8MXY0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stx4_human(display_long)|uniprotkb:Renal carcinoma antigen NY-REN-31(gene name synonym)|uniprotkb:STX4(gene name)|psi-mi:STX4(display_short)|uniprotkb:STX4A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000103496(gene)|refseq:NP_004595.2|ensembl:ENST00000313843(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0000322"(storage vacuole)|go:"GO:0002639"(positive regulation of immunoglobulin production)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005768"(endosome)|go:"GO:0005773"(vacuole)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006887"(exocytosis)|go:"GO:0006906"(vesicle fusion)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009986"(cell surface)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016230"(sphingomyelin phosphodiesterase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030027"(lamellipodium)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0032589"(neuron projection membrane)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035749"(myelin sheath adaxonal region)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0036477"(somatodendritic compartment)|go:"GO:0042581"(specific granule)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0043197"(dendritic spine)|go:"GO:0043219"(lateral loop)|go:"GO:0043311"(positive regulation of eosinophil degranulation)|go:"GO:0045202"(synapse)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0048278"(vesicle docking)|go:"GO:0048284"(organelle fusion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048787"(presynaptic active zone membrane)|go:"GO:0050921"(positive regulation of chemotaxis)|go:"GO:0060291"(long-term synaptic potentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902041"(regulation of extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903575"(cornified envelope assembly)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|reactome:R-HSA-114516|reactome:R-HSA-1236974|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-449836|interpro:IPR006011(Syntaxin, N-terminal)|refseq:NP_001259025.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NvOLGIGe/XO2aDPSpdPzrtKniZY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P47756 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353595|uniprotkb:Q5U0L4|uniprotkb:Q8TB49|uniprotkb:Q9NUC4|uniprotkb:Q32Q68|ensembl:ENSP00000364284|ensembl:ENSP00000501528 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:capzb_human(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001193469.1|refseq:NP_004921.1|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051490"(negative regulation of filopodium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|go:"GO:0097224"(sperm connecting piece)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|interpro:IPR001698(F-actin capping protein, beta subunit)|interpro:IPR019771|interpro:IPR037282|interpro:IPR042276|interpro:IPR043175|mint:P47756|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-9013405|reactome:R-HSA-9035034|reactome:R-HSA-9662360|reactome:R-HSA-983231|ensembl:ENSG00000077549(gene)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005903"(brush border)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0030017"(sarcomere)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030863"(cortical cytoskeleton)|refseq:NP_001269091.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H3P7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1791792|uniprotkb:Q5VTJ0|uniprotkb:Q6P9F1|uniprotkb:Q8IZC5|uniprotkb:Q8N4D6|uniprotkb:Q9H6U3|uniprotkb:B2RB29|ensembl:ENSP00000355777 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gcp60_human(display_long)|uniprotkb:GOCAP1(gene name synonym)|uniprotkb:GOLPH1(gene name synonym)|uniprotkb:ACBD3(gene name)|psi-mi:ACBD3(display_short)|uniprotkb:GCP60(gene name synonym)|uniprotkb:Acyl-CoA-binding domain-containing protein 3(gene name synonym)|uniprotkb:Golgi phosphoprotein 1(gene name synonym)|uniprotkb:Golgi complex-associated protein 1(gene name synonym)|uniprotkb:PBR- and PKA-associated protein 7(gene name synonym)|uniprotkb:Peripheral benzodiazepine receptor-associated protein PAP7(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_073572.2|dip:DIP-40673N|ensembl:ENSG00000182827(gene)|ensembl:ENST00000366812(transcript)|go:"GO:0000062"(fatty-acyl-CoA binding)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006694"(steroid biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|interpro:IPR000582(Acyl-CoA-binding protein, ACBP)|interpro:IPR009038(GOLD)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR022408|interpro:IPR035984|interpro:IPR036598|mint:Q9H3P7|rcsb pdb:2N72|rcsb pdb:2N73|rcsb pdb:5LZ1|rcsb pdb:5LZ3|rcsb pdb:5LZ6|rcsb pdb:5TDQ|rcsb pdb:6HLN|rcsb pdb:6HLT|rcsb pdb:6HLV|rcsb pdb:6HLW|rcsb pdb:6HM8|rcsb pdb:6HMV|reactome:R-HSA-432722 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:jAaMXnoXG6RGj+lAgIYk1inXA6o9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9ULT0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2844096|uniprotkb:Q6PIX4|uniprotkb:Q9BUS3|uniprotkb:Q8ND67|uniprotkb:Q2T9J9|ensembl:ENSP00000316699 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ttc7a_human(display_long)|uniprotkb:TTC7A(gene name)|psi-mi:TTC7A(display_short)|uniprotkb:KIAA1140(gene name synonym)|uniprotkb:TTC7(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_065191.2|refseq:NP_001275880.1|refseq:NP_001275882.1|refseq:NP_001275884.1|ensembl:ENSG00000068724(gene)|ensembl:ENST00000319190(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006879"(cellular iron ion homeostasis)|go:"GO:0030097"(hemopoiesis)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR026900 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZxOOuhpKuSn+quIkbCHDb1HVCjo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13938 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-21820563|uniprotkb:A0A0X1KG78|uniprotkb:K7EL21|uniprotkb:Q3MJA7|uniprotkb:Q8NF12|uniprotkb:Q8WUZ3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cayp1_human(display_long)|uniprotkb:Calcyphosine(gene name synonym)|uniprotkb:CAPS(gene name)|psi-mi:CAPS(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004049.2|refseq:NP_542157.2|rcsb pdb:3E3R|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR002048(Calcium-binding EF-hand)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0031982"(vesicle)|go:"GO:0035556"(intracellular signal transduction) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3mAKGNlKTe20V3NZHXBMLk1A9HY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IUD2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1044755|uniprotkb:Q6NVK2|uniprotkb:Q8IUD3|uniprotkb:Q8IUD4|uniprotkb:Q8IUD5|uniprotkb:Q8NAS1|uniprotkb:Q9NXN5|uniprotkb:Q9UIK7|uniprotkb:Q9UPS1|intact:EBI-3645200|uniprotkb:A7E295|ensembl:ENSP00000354158|ensembl:ENSP00000468263|uniprotkb:D3DUP7|uniprotkb:D3DUP8|uniprotkb:A2RU77 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rb6i2_human(display_long)|uniprotkb:Rab6-interacting protein 2(gene name synonym)|uniprotkb:ERC1(gene name)|psi-mi:ERC1(display_short)|uniprotkb:ELKS(gene name synonym)|uniprotkb:KIAA1081(gene name synonym)|uniprotkb:RAB6IP2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_829883.1|refseq:NP_829884.1|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0015031"(protein transport)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043522"(leucine zipper domain binding)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0048788"(cytoskeleton of presynaptic active zone)|go:"GO:0007275"(multicellular organism development)|go:"GO:0048790"(maintenance of presynaptic active zone structure)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0098882"(structural constituent of presynaptic active zone)|interpro:IPR019018|interpro:IPR019323|interpro:IPR037245|ensembl:ENSG00000082805(gene)|ensembl:ENST00000360905(transcript)|ensembl:ENST00000589028(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007274"(neuromuscular synaptic transmission)|refseq:XP_016874553.1|refseq:XP_016874556.1|refseq:XP_011519243.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0W5DM0QbKuWdMW4T+pJKPT7pKgA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75864 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-5235692|uniprotkb:Q8IWK3|uniprotkb:Q8TF16|uniprotkb:B5MDA4|ensembl:ENSP00000221462 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ppr37_human(display_long)|uniprotkb:PPP1R37(gene name)|psi-mi:PPP1R37(display_short)|uniprotkb:KIAA1986(gene name synonym)|uniprotkb:LRRC68(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 68(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_061994.1|ensembl:ENSG00000104866(gene)|ensembl:ENST00000221462(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR032675 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0tihbZMwT+ENzQPeu4vUmUztJFY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WXE0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2622376|uniprotkb:B4DTT3|uniprotkb:Q9ULT1|intact:EBI-3446386|uniprotkb:B7Z9H1|uniprotkb:Q7LG69|ensembl:ENSP00000325355 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cski2_human(display_long)|uniprotkb:CASK-interacting protein 2(gene name synonym)|uniprotkb:CASKIN2(gene name)|psi-mi:CASKIN2(display_short)|uniprotkb:KIAA1139(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001136115.1|refseq:NP_065804.2|ensembl:ENSP00000325355|ensembl:ENST00000433559|ensembl:ENSP00000406963|ensembl:ENSG00000177303(gene)|ensembl:ENST00000321617(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0016020"(membrane)|interpro:IPR001452(Src homology-3)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR002110(Ankyrin)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR027013|interpro:IPR032117|interpro:IPR032232|interpro:IPR035497|interpro:IPR035498|interpro:IPR035499|interpro:IPR036028|interpro:IPR036770|rcsb pdb:2KE9|rcsb pdb:4IS7|rcsb pdb:5L1M - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XLOkvhXMcYWuzRMNrR3q+K4PoCg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9ULH1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-346622|uniprotkb:B2RNV3|ensembl:ENSP00000429900 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:asap1_human(display_long)|uniprotkb:ASAP1(gene name)|psi-mi:ASAP1(display_short)|uniprotkb:DDEF1(gene name synonym)|uniprotkb:KIAA1249(gene name synonym)|uniprotkb:PIP2-dependent ARF1 GAP(gene name synonym)|uniprotkb:ADP-ribosylation factor-directed GTPase-activating protein 1(gene name synonym)|uniprotkb:Development and differentiation-enhancing factor 1(gene name synonym)|uniprotkb:130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein(gene name synonym)|uniprotkb:PAG2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_006716626.1|refseq:XP_005250982.1|refseq:NP_060952.2|ensembl:ENSP00000429900|refseq:NP_001234925.1|refseq:XP_011515354.1|rcsb pdb:2DA0|rcsb pdb:2ED1|rcsb pdb:2RQT|rcsb pdb:2RQU|reactome:R-HSA-5620916|ensembl:ENSG00000153317(gene)|ensembl:ENST00000518721(transcript)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0002102"(podosome)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005829"(cytosol)|go:"GO:0031253"(cell projection membrane)|go:"GO:0043197"(dendritic spine)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0061000"(negative regulation of dendritic spine development)|go:"GO:0071803"(positive regulation of podosome assembly)|go:"GO:1903527"(positive regulation of membrane tubulation)|interpro:IPR001164(Arf GTPase activating protein)|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002110(Ankyrin)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR020683|interpro:IPR027267|interpro:IPR036028|interpro:IPR036770|interpro:IPR037278|interpro:IPR037844|interpro:IPR037928|interpro:IPR038016|interpro:IPR038508|interpro:IPR043593|mint:Q9ULH1|rcsb pdb:2D1X - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:SNTUJDKJY1SYZwUBev1peWcNArw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14258 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2341129|intact:EBI-28973868|ensembl:ENSP00000323889|ensembl:ENSP00000445961 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tri25_human(display_long)|uniprotkb:TRIM25(gene name)|psi-mi:TRIM25(display_short)|uniprotkb:EFP(gene name synonym)|uniprotkb:RNF147(gene name synonym)|uniprotkb:ZNF147(gene name synonym)|uniprotkb:Zinc finger protein 147(gene name synonym)|uniprotkb:Estrogen-responsive finger protein(gene name synonym)|uniprotkb:RING finger protein 147(gene name synonym)|uniprotkb:Ubiquitin/ISG15-conjugating enzyme TRIM25(gene name synonym)|uniprotkb:Tripartite motif-containing protein 25(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase(gene name synonym)|uniprotkb:RING-type E3 ubiquitin transferase TRIM25(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000323889|ensembl:ENSP00000445961|refseq:NP_005073.2|ensembl:ENSG00000121060(gene)|ensembl:ENST00000316881(transcript)|ensembl:ENST00000537230(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0006513"(protein monoubiquitination)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016604"(nuclear body)|go:"GO:0016874"(ligase activity)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033280"(response to vitamin D)|go:"GO:0039552"(RIG-I binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043627"(response to estrogen)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046597"(negative regulation of viral entry into host cell)|go:"GO:0046872"(metal ion binding)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051607"(defense response to virus)|go:"GO:0061630"(ubiquitin protein ligase activity)|go:"GO:1902186"(obsolete regulation of viral release from host cell)|go:"GO:1902187"|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR001841(Zinc finger, RING-type)|interpro:IPR001870("B302 (SPRY)-like")|interpro:IPR003877(SPla/RYanodine receptor SPRY)|interpro:IPR003879(Butyrophylin-like)|interpro:IPR006574(SPRY-associated)|interpro:IPR013083(Zinc finger, RING/FYVE/PHD-type)|interpro:IPR013320(Concanavalin A-like lectin/glucanase, subgroup)|interpro:IPR017907|interpro:IPR042753|interpro:IPR043136|mint:Q14258|rcsb pdb:4CFG|rcsb pdb:4LTB|rcsb pdb:5EYA|rcsb pdb:5FER|rcsb pdb:5NT1|rcsb pdb:5NT2|rcsb pdb:6FLM|rcsb pdb:6FLN|reactome:R-HSA-1169408|reactome:R-HSA-168928|reactome:R-HSA-5656169|reactome:R-HSA-5689896|reactome:R-HSA-877300|reactome:R-HSA-918233|reactome:R-HSA-933541|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-936440 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NhFfC0IxHvxPIt2YnKCPsPKuiQA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P52566 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2806617|uniprotkb:B5BU79|ensembl:ENSP00000228945|ensembl:ENSP00000440560|ensembl:ENSP00000444860 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gdir2_human(display_long)|uniprotkb:GDIA2(gene name synonym)|uniprotkb:GDID4(gene name synonym)|uniprotkb:RAP1GN1(gene name synonym)|uniprotkb:Ly-GDI(gene name synonym)|uniprotkb:Rho-GDI beta(gene name synonym)|uniprotkb:ARHGDIB(gene name)|psi-mi:ARHGDIB(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001166.3|ensembl:ENSG00000111348(gene)|ensembl:ENST00000541546(transcript)|ensembl:ENST00000541644(transcript)|go:"GO:0003924"(GTPase activity)|go:"GO:0005094"(Rho GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007162"(negative regulation of cell adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016020"(membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071461"(cellular response to redox state)|go:"GO:1901164"(negative regulation of trophoblast cell migration)|ensembl:ENST00000228945(transcript)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR000406(RHO protein GDP dissociation inhibitor)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR024792|mint:P52566|rcsb pdb:1DS6|rcsb pdb:5H1D|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013423|refseq:NP_001308349.1|refseq:NP_001308350.1|refseq:NP_001308351.1|refseq:NP_001308352.1|dip:DIP-40959N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:uiFgGyiT2vBDU0XIRX2ix/bDmHw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P11021 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-354921|ensembl:ENSP00000324173|uniprotkb:Q2EF78|uniprotkb:Q9NPF1|uniprotkb:Q9UK02|uniprotkb:B0QZ61 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:bip_human(display_long)|uniprotkb:HSPA5(gene name)|psi-mi:HSPA5(display_short)|uniprotkb:GRP78(gene name synonym)|uniprotkb:Immunoglobulin heavy chain-binding protein(gene name synonym)|uniprotkb:78 kDa glucose-regulated protein(gene name synonym)|uniprotkb:Binding-immunoglobulin protein(gene name synonym)|uniprotkb:Heat shock protein 70 family protein 5(gene name synonym)|uniprotkb:Heat shock protein family A member 5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000044574(gene)|ensembl:ENST00000324460(transcript)|go:"GO:0001554"(luteolysis)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006983"(ER overload response)|refseq:NP_005338.1|go:"GO:0009986"(cell surface)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0021589"(cerebellum structural organization)|go:"GO:0021680"(cerebellar Purkinje cell layer development)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030433"(ubiquitin-dependent ERAD pathway)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031204"(posttranslational protein targeting to membrane, translocation)|go:"GO:0031333"(negative regulation of protein-containing complex assembly)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034663"(endoplasmic reticulum chaperone complex)|go:"GO:0034975"(protein folding in endoplasmic reticulum)|go:"GO:0035437"(maintenance of protein localization in endoplasmic reticulum)|go:"GO:0035690"|go:"GO:0042026"(protein refolding)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042220"(response to cocaine)|go:"GO:0042470"(melanosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051402"(neuron apoptotic process)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0060904"(regulation of protein folding in endoplasmic reticulum)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071236"(cellular response to antibiotic)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071287"(cellular response to manganese ion)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0097501"(stress response to metal ion)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901998"(toxin transport)|go:"GO:1903891"(regulation of ATF6-mediated unfolded protein response)|go:"GO:1903894"(regulation of IRE1-mediated unfolded protein response)|go:"GO:1903895"(negative regulation of IRE1-mediated unfolded protein response)|go:"GO:1903897"(regulation of PERK-mediated unfolded protein response)|go:"GO:1904313"(response to methamphetamine hydrochloride)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990440"(positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR042050|interpro:IPR043129|mint:P11021|rcsb pdb:3IUC|rcsb pdb:3LDL|rcsb pdb:3LDN|rcsb pdb:3LDO|rcsb pdb:3LDP|rcsb pdb:5E84|rcsb pdb:5E85|rcsb pdb:5E86|rcsb pdb:5EVZ|rcsb pdb:5EX5|rcsb pdb:5EXW|rcsb pdb:5EY4|rcsb pdb:5F0X|rcsb pdb:5F1X|rcsb pdb:5F2R|rcsb pdb:6ASY|rcsb pdb:6CZ1|rcsb pdb:6DFM|rcsb pdb:6DFO|rcsb pdb:6DO2|rcsb pdb:6DWS|rcsb pdb:6ZMD|reactome:R-HSA-114608|reactome:R-HSA-3371453|reactome:R-HSA-381033|reactome:R-HSA-381042|reactome:R-HSA-381070|reactome:R-HSA-381183|reactome:R-HSA-983170|dip:DIP-33189N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:O8nTjCciNhD3QsbZmbolQ1IIMn49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NEJ9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-9995414|uniprotkb:A8K760|uniprotkb:Q9Y400|ensembl:ENSP00000386134 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ngdn_human(display_long)|uniprotkb:NGDN(gene name)|psi-mi:NGDN(display_short)|uniprotkb:C14orf120(gene name synonym)|uniprotkb:Centromere accumulated nuclear protein 1(gene name synonym)|uniprotkb:EIF4E-binding protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001036100.1|refseq:NP_056329.1|ensembl:ENSG00000129460(gene)|ensembl:ENST00000408901(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005739"(mitochondrion)|go:"GO:0006417"(regulation of translation)|go:"GO:0030175"(filopodium)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0032040"(small-subunit processome)|interpro:IPR007146(Small-subunit processome, Utp3)|mint:Q8NEJ9 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:dzn7QntKCrb97VLlmUMizp+0CV49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96AG4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-358888|uniprotkb:Q9P189|uniprotkb:D3DTX8|ensembl:ENSP00000225972|uniprotkb:B2RE83 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lrc59_human(display_long)|uniprotkb:LRRC59(gene name)|psi-mi:LRRC59(display_short)|uniprotkb:Ribosome-binding protein p34(gene name synonym)|uniprotkb:PRO1855(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060979.2|ensembl:ENSG00000108829(gene)|ensembl:ENST00000225972(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0045296"(cadherin binding)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|mint:Q96AG4 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:gAtWed9Jv69oHdkEFgpWGFnvcWE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P49959 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-396513|uniprotkb:O43475|uniprotkb:B3KTC7|ensembl:ENSP00000325863 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mre11_human(display_long)|uniprotkb:MRE11(gene name)|psi-mi:MRE11(display_short)|uniprotkb:Double-strand break repair protein MRE11A(gene name synonym)|uniprotkb:HNGS1(gene name synonym)|uniprotkb:MRE11A(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog 1(gene name synonym)|uniprotkb:Meiotic recombination 11 homolog A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005581.2|refseq:NP_005582.1|refseq:XP_011541139.1|refseq:XP_016873261.1|dip:DIP-33238N|ensembl:ENSG00000020922(gene)|ensembl:ENST00000323929(transcript)|go:"GO:0000014"(single-stranded DNA endodeoxyribonuclease activity)|go:"GO:0000019"(regulation of mitotic recombination)|go:"GO:0000723"(telomere maintenance)|go:"GO:0000724"(double-strand break repair via homologous recombination)|go:"GO:0000729"(DNA double-strand break processing)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005657"(replication fork)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006281"(DNA repair)|go:"GO:0006302"(double-strand break repair)|go:"GO:0006303"(double-strand break repair via nonhomologous end joining)|go:"GO:0006310"(DNA recombination)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007004"(telomere maintenance via telomerase)|go:"GO:0007062"(sister chromatid cohesion)|go:"GO:0007095"(mitotic G2 DNA damage checkpoint signaling)|go:"GO:0007129"(homologous chromosome pairing at meiosis)|go:"GO:0007131"(reciprocal meiotic recombination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008296"(3'-5'-exodeoxyribonuclease activity)|go:"GO:0008408"(3'-5' exonuclease activity)|go:"GO:0008409"(5'-3' exonuclease activity)|go:"GO:0016605"(PML body)|go:"GO:0030145"(manganese ion binding)|go:"GO:0030870"(Mre11 complex)|go:"GO:0031573"(mitotic intra-S DNA damage checkpoint signaling)|go:"GO:0031860"(telomeric 3' overhang formation)|go:"GO:0031954"(positive regulation of protein autophosphorylation)|go:"GO:0032206"(positive regulation of telomere maintenance)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042138"(meiotic DNA double-strand break formation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0097552"(mitochondrial double-strand break repair via homologous recombination)|go:"GO:0110025"(DNA strand resection involved in replication fork processing)|interpro:IPR003701(DNA repair exonuclease)|interpro:IPR004843(Metallophosphoesterase)|interpro:IPR007281(Mre11, DNA-binding)|interpro:IPR029052|interpro:IPR038487|interpro:IPR041796|mint:P49959|rcsb pdb:3T1I|reactome:R-HSA-1834949|reactome:R-HSA-2559586|reactome:R-HSA-3270619|reactome:R-HSA-5685938|reactome:R-HSA-5685939|reactome:R-HSA-5685942|reactome:R-HSA-5693548|reactome:R-HSA-5693554|reactome:R-HSA-5693565|reactome:R-HSA-5693568|reactome:R-HSA-5693571|reactome:R-HSA-5693579|reactome:R-HSA-5693607|reactome:R-HSA-5693616|reactome:R-HSA-6804756|reactome:R-HSA-69473|reactome:R-HSA-912446 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fgwgA0BcNZ9phGBaOSYjkldDgeI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P29966 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1047781|uniprotkb:E1P560|uniprotkb:Q2LA83|uniprotkb:Q5TDB7|ensembl:ENSP00000478061 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:marcs_human(display_long)|uniprotkb:Protein kinase C substrate, 80 kDa protein, light chain(gene name synonym)|uniprotkb:MARCKS(gene name)|psi-mi:MARCKS(display_short)|uniprotkb:MACS(gene name synonym)|uniprotkb:PRKCSL(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002347.5|ensembl:ENSG00000277443(gene)|ensembl:ENST00000612661(transcript)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007015"(actin filament organization)|go:"GO:0007417"(central nervous system development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0032432"(actin filament bundle)|go:"GO:0042585"(germinal vesicle)|go:"GO:0042802"(identical protein binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002101(Myristoylated alanine-rich C-kinase substrate MARCKS)|mint:P29966|reactome:R-HSA-399997 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:28v6sOqwULr0AvfJr7yAal9Yh1g9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P0DMV8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11052499|uniprotkb:Q9UQM0|uniprotkb:Q5SP17|uniprotkb:Q5JQI4|uniprotkb:P08107|uniprotkb:B4E3B6|uniprotkb:Q9UQL9|uniprotkb:P19790|ensembl:ENSP00000364802|ensembl:ENSP00000382915|ensembl:ENSP00000404524|ensembl:ENSP00000406359|ensembl:ENSP00000408907 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:hs71a_human(display_long)|uniprotkb:HSPA1A(gene name)|psi-mi:HSPA1A(display_short)|uniprotkb:HSPA1(gene name synonym)|uniprotkb:HSX70(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 1(gene name synonym)|uniprotkb:HSP72(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005336.3|refseq:NP_005337.2|ensembl:ENSG00000204389(gene)|ensembl:ENSG00000215328(gene)|ensembl:ENSG00000234475(gene)|ensembl:ENSG00000235941(gene)|ensembl:ENSG00000237724(gene)|ensembl:ENST00000375651(transcript)|ensembl:ENST00000400040(transcript)|ensembl:ENST00000430065(transcript)|ensembl:ENST00000433487(transcript)|ensembl:ENST00000441618(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006402"(mRNA catabolic process)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0007041"(lysosomal transport)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016234"(inclusion body)|go:"GO:0016235"(aggresome)|go:"GO:0016607"(nuclear speck)|go:"GO:0019899"(enzyme binding)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031249"(denatured protein binding)|go:"GO:0031396"(regulation of protein ubiquitination)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031982"(vesicle)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032757"(positive regulation of interleukin-8 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033120"(positive regulation of RNA splicing)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042026"(protein refolding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051131"(chaperone-mediated protein complex assembly)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070370"(cellular heat acclimation)|go:"GO:0070434"(positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0072562"(blood microparticle)|go:"GO:0090063"(positive regulation of microtubule nucleation)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1901029"(negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902236"(negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1902380"(positive regulation of endoribonuclease activity)|go:"GO:1903265"(positive regulation of tumor necrosis factor-mediated signaling pathway)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P0DMV8|rcsb pdb:1HJO|rcsb pdb:1S3X|rcsb pdb:1XQS|rcsb pdb:2E88|rcsb pdb:2E8A|rcsb pdb:2LMG|rcsb pdb:3A8Y|rcsb pdb:3ATU|rcsb pdb:3ATV|rcsb pdb:3AY9|rcsb pdb:3D2E|rcsb pdb:3D2F|rcsb pdb:3JXU|rcsb pdb:3LOF|rcsb pdb:3Q49|rcsb pdb:4IO8|rcsb pdb:4J8F|rcsb pdb:4PO2|rcsb pdb:4WV5|rcsb pdb:4WV7|rcsb pdb:5AQW|rcsb pdb:5AQX|rcsb pdb:5AQY|rcsb pdb:5AQZ|rcsb pdb:5AR0|rcsb pdb:5BN8|rcsb pdb:5BN9|rcsb pdb:5BPL|rcsb pdb:5BPM|rcsb pdb:5BPN|rcsb pdb:5GJJ|rcsb pdb:5MKR|rcsb pdb:5MKS|rcsb pdb:5XI9|rcsb pdb:5XIR|rcsb pdb:6FHK|rcsb pdb:6G3R|rcsb pdb:6G3S|rcsb pdb:6JPV|rcsb pdb:6K39|reactome:R-HSA-168330|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-450408|reactome:R-HSA-6798695 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NFv4uj12xAWIr+OltarRlLDPr949606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O14618 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11668690|uniprotkb:Q2M366|uniprotkb:Q8NEV0|ensembl:ENSP00000436318 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ccs_human(display_long)|uniprotkb:CCS(gene name)|psi-mi:CCS(display_short)|uniprotkb:Superoxide dismutase copper chaperone(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005116.1|ensembl:ENSG00000173992(gene)|ensembl:ENST00000533244(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006801"(superoxide metabolic process)|go:"GO:0015035"(protein-disulfide reductase activity)|go:"GO:0015680"(protein maturation by copper ion transfer)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0045296"(cadherin binding)|go:"GO:0051353"(positive regulation of oxidoreductase activity)|interpro:IPR001424(Superoxide dismutase, copper/zinc binding)|interpro:IPR006121(Heavy metal transport/detoxification protein)|interpro:IPR018152|interpro:IPR024134|interpro:IPR036163|interpro:IPR036423|mint:O14618|rcsb pdb:1DO5|rcsb pdb:2CRL|rcsb pdb:2RSQ|rcsb pdb:6FN8|rcsb pdb:6FOL|rcsb pdb:6FON|rcsb pdb:6FP6|reactome:R-HSA-3299685 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:r5pGUXbIewnEFuTqrKn78aG7N309606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96HB5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-744556|uniprotkb:B4DTU2|ensembl:ENSP00000470294|ensembl:ENSP00000474761|ensembl:ENSP00000475676|uniprotkb:A8K5Q5|uniprotkb:B4DF24|uniprotkb:F5GZU4|uniprotkb:B4DFC1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cc120_human(display_long)|uniprotkb:CCDC120(gene name)|psi-mi:CCDC120(display_short)|uniprotkb:JM11(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001156795.1|refseq:NP_296375.1|go:"GO:0005814"(centriole)|go:"GO:0008104"(protein localization)|go:"GO:0030426"(growth cone)|go:"GO:0034454"(microtubule anchoring at centrosome)|go:"GO:0120103"(centriolar subdistal appendage)|interpro:IPR021774|interpro:IPR039108|interpro:IPR043447|ensembl:ENSG00000147144(gene)|ensembl:ENST00000496529(transcript)|ensembl:ENST00000597275(transcript)|ensembl:ENST00000606812(transcript)|go:"GO:0005768"(endosome)|refseq:NP_001258764.1|refseq:NP_001258765.1|refseq:NP_001156793.2|refseq:NP_001156794.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:uBgmQJDTqECaTKOU/uQQHkWB/Nc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95433 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-448610|uniprotkb:Q9P060|uniprotkb:Q96IL6|uniprotkb:B2R9L2|uniprotkb:B4DUR9|ensembl:ENSP00000216479 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ahsa1_human(display_long)|uniprotkb:HSPC322(orf name)|uniprotkb:p38(gene name synonym)|uniprotkb:AHSA1(gene name)|psi-mi:AHSA1(display_short)|uniprotkb:C14orf3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_036243.1|refseq:NP_001308370.1|ensembl:ENSG00000100591(gene)|ensembl:ENST00000216479(transcript)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006457"(protein folding)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051087"(chaperone binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR013538(Activator of Hsp90 ATPase homologue 1-like)|interpro:IPR015310(Activator of Hsp90 ATPase, N-terminal)|interpro:IPR023393|interpro:IPR036338|interpro:IPR039981|mint:O95433|rcsb pdb:1X53|rcsb pdb:7DMD|rcsb pdb:7DME|go:"GO:0051879"(Hsp90 protein binding) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:HUgJrOxubEHSPst5ZQNxSC38QvY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NUQ8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-717672|uniprotkb:Q86UA2|uniprotkb:Q8NAN1|uniprotkb:Q96GS8|uniprotkb:Q9H7A8|uniprotkb:A8K241|ensembl:ENSP00000411471 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:abcf3_human(display_long)|uniprotkb:ABCF3(gene name)|psi-mi:ABCF3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060828.2|ensembl:ENSG00000161204(gene)|ensembl:ENST00000429586(transcript)|interpro:IPR003593(AAA+ ATPase, core)|go:"GO:0005524"(ATP binding)|interpro:IPR017871|interpro:IPR027417|interpro:IPR032781|go:"GO:0016020"(membrane)|mint:Q9NUQ8|go:"GO:0042626"(ATPase-coupled transmembrane transporter activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051607"(defense response to virus)|interpro:IPR003439(ABC transporter-like) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lCleN3/TzwUbPMZzkKRJzNygge89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H8Y8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-739467|uniprotkb:Q96I74|uniprotkb:Q96K84|uniprotkb:Q9H946|uniprotkb:Q9UFW4|uniprotkb:Q53TE3|intact:EBI-28970723|uniprotkb:B4DKT0|ensembl:ENSP00000234160 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gors2_human(display_long)|uniprotkb:GORASP2(gene name)|psi-mi:GORASP2(display_short)|uniprotkb:Golgi reassembly-stacking protein of 55 kDa(gene name synonym)|uniprotkb:p59(gene name synonym)|uniprotkb:Golgi phosphoprotein 6(gene name synonym)|uniprotkb:GOLPH6(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000234160|refseq:NP_001188357.1|refseq:NP_056345.3|refseq:XP_006712471.1|ensembl:ENSG00000115806(gene)|ensembl:ENST00000234160(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0006996"(organelle organization)|go:"GO:0007030"(Golgi organization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0016020"(membrane)|go:"GO:0030154"(cell differentiation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070925"(organelle assembly)|interpro:IPR007583(GRASP55/65)|interpro:IPR024958|interpro:IPR036034|mint:Q9H8Y8|rcsb pdb:3RLE|rcsb pdb:4EDJ|reactome:R-HSA-162658 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xSy3HsObmteg/doer5eLoZiz+fU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H792 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2609701|uniprotkb:Q6ZS78|uniprotkb:Q8TEG7|uniprotkb:Q8NCM3|uniprotkb:Q8NAZ4|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:peak1_human(display_long)|uniprotkb:PEAK1(gene name)|psi-mi:PEAK1(display_short)|uniprotkb:KIAA2002(gene name synonym)|uniprotkb:Sugen kinase 269(gene name synonym)|uniprotkb:Tyrosine-protein kinase SgK269(gene name synonym)|uniprotkb:Pseudopodium-enriched atypical kinase 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011520335.1|refseq:XP_011520336.1|refseq:XP_011520337.1|refseq:XP_011520338.1|refseq:XP_011520339.1|refseq:XP_011520341.1|refseq:XP_011520340.1|refseq:NP_079052.2|refseq:XP_005254727.1|refseq:XP_005254728.1|refseq:XP_005254730.1|refseq:XP_005254731.1|refseq:XP_005254732.1|ensembl:ENSG00000173517(gene)|ensembl:ENST00000312493(transcript)|ensembl:ENST00000560626(transcript)|ensembl:ENST00000682557(transcript)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0042802"(identical protein binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|rcsb pdb:6BHC|reactome:R-HSA-9013420|reactome:R-HSA-9013424|ensembl:ENSP00000309230|ensembl:ENSP00000452796|ensembl:ENSP00000507603|dip:DIP-56276N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:z2Q9mOQSYpc1fQJHovBCFsctX749606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H223 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1050573|uniprotkb:Q9HAR1|uniprotkb:Q9NZN2|ensembl:ENSP00000220325 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ehd4_human(display_long)|uniprotkb:Hepatocellular carcinoma-associated protein 10/11(gene name synonym)|uniprotkb:EHD4(gene name)|psi-mi:EHD4(display_short)|uniprotkb:HCA10(gene name synonym)|uniprotkb:HCA11(gene name synonym)|uniprotkb:FKSG7(orf name)|uniprotkb:PAST4(gene name synonym)|uniprotkb:PAST homolog 4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_644670.1|ensembl:ENSG00000103966(gene)|ensembl:ENST00000220325(transcript)|go:"GO:0003676"(nucleic acid binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0006907"(pinocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029952|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H223 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WtFn0GamyqosWQvcBXdhbtjJ3Fw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P53365 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-638194|uniprotkb:D3DQT5|ensembl:ENSP00000254584|ensembl:ENSP00000379998|uniprotkb:B4E306|uniprotkb:B4DX86 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:arfp2_human(display_long)|uniprotkb:ADP-ribosylation factor-interacting protein 2(gene name synonym)|uniprotkb:Partner of RAC1(gene name synonym)|uniprotkb:ARFIP2(gene name)|psi-mi:ARFIP2(display_short)|uniprotkb:POR1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001229784.1|refseq:NP_036534.1|ensembl:ENSG00000132254(gene)|ensembl:ENST00000254584(transcript)|ensembl:ENST00000396777(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005525"(GTP binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006914"(autophagy)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030742"(GTP-dependent protein binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031529"(ruffle organization)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0140090"(membrane curvature sensor activity)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030798|rcsb pdb:1I49|rcsb pdb:1I4D|rcsb pdb:1I4L|rcsb pdb:1I4T|rcsb pdb:4DCN|reactome:R-HSA-6811440|refseq:NP_001229785.1|refseq:XP_005252897.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:q3QMUWlBIW82Szrv9jbMR6ikOZg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6PKG0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1052114|uniprotkb:O94836|uniprotkb:Q8N4M2|uniprotkb:Q8NB73|uniprotkb:Q9UFD7|ensembl:ENSP00000428589 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:larp1_human(display_long)|uniprotkb:La ribonucleoprotein domain family member 1(gene name synonym)|uniprotkb:LARP1(gene name)|psi-mi:LARP1(display_short)|uniprotkb:KIAA0731(gene name synonym)|uniprotkb:LARP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_056130.2|ensembl:ENST00000336314|ensembl:ENSP00000336721|ensembl:ENSP00000428589|refseq:XP_005268461.1|ensembl:ENSG00000155506(gene)|ensembl:ENST00000518297(transcript)|go:"GO:0000339"(RNA cap binding)|go:"GO:0000340"(RNA 7-methylguanosine cap binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006413"(translational initiation)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008494"(translation activator activity)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010608"(posttranscriptional regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031929"(TOR signaling)|go:"GO:0038202"(TORC1 signaling)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0045948"(positive regulation of translational initiation)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0048255"(mRNA stabilization)|go:"GO:0072752"(cellular response to rapamycin)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR006607(Protein of unknown function DM15)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR036388|interpro:IPR036390|mint:Q6PKG0|rcsb pdb:4ZC4|rcsb pdb:5C0V|rcsb pdb:5V4R|rcsb pdb:5V7C|rcsb pdb:5V87|rcsb pdb:6PW3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:TjQrZVRN3opAdFIWZtaEopFZf8I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O94929 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351267|uniprotkb:A8K121|uniprotkb:Q19VH3|uniprotkb:Q658S1|uniprotkb:Q68CI5|uniprotkb:Q9BV32|ensembl:ENSP00000310309|ensembl:ENSP00000425394 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ablm3_human(display_long)|uniprotkb:ABLIM3(gene name)|psi-mi:ABLIM3(display_short)|uniprotkb:HMFN1661(orf name)|uniprotkb:KIAA0843(gene name synonym)|uniprotkb:Actin-binding LIM protein family member 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055760.1|refseq:NP_001287944.1|refseq:NP_001287947.1|refseq:NP_001287957.1|ensembl:ENSG00000173210(gene)|ensembl:ENST00000309868(transcript)|ensembl:ENST00000506113(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0060271"(cilium assembly)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003128(Villin headpiece)|interpro:IPR028449|interpro:IPR032402|interpro:IPR036886|rcsb pdb:1UJS|rcsb pdb:2DJ7|reactome:R-HSA-418885|refseq:NP_001287956.1|refseq:NP_001332787.1|refseq:NP_001332788.1|refseq:NP_001332789.1|refseq:NP_001332790.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:hkH6gCL3p11Wrl6ixVvtl/MGhsI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q12792 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1056675|uniprotkb:Q6NUK9|uniprotkb:A8K5A8|uniprotkb:Q59G07|uniprotkb:Q5U0B1|uniprotkb:Q6FHJ1|uniprotkb:Q6FHL6|uniprotkb:Q86XL6|uniprotkb:Q8TCD3|ensembl:ENSP00000378886|uniprotkb:B3KXS6|uniprotkb:B4DLX9 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:twf1_human(display_long)|uniprotkb:TWF1(gene name)|psi-mi:TWF1(display_short)|uniprotkb:PTK9(gene name synonym)|uniprotkb:Protein A6(gene name synonym)|uniprotkb:Protein tyrosine kinase 9(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000151239(gene)|ensembl:ENST00000395510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0010613"(positive regulation of cardiac muscle hypertrophy)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0030016"(myofibril)|go:"GO:0030042"(actin filament depolymerization)|go:"GO:0030175"(filopodium)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042989"(sequestering of actin monomers)|go:"GO:0043538"(regulation of actin phosphorylation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028458|interpro:IPR029006|mint:Q12792|refseq:NP_001229326.1|refseq:NP_002813.3|rcsb pdb:7CCC|reactome:R-HSA-9013418|reactome:R-HSA-9662360|reactome:R-HSA-9662361 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:5yv7DC8rsBmxmXtzv40wJ/U154c9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q4KMP7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4402442|uniprotkb:B9A6L0|uniprotkb:Q6IN54|uniprotkb:Q6P530|uniprotkb:Q71RG7|uniprotkb:Q86VC5|uniprotkb:Q9H8Z2|uniprotkb:Q9NUN6|uniprotkb:Q9UFP2|ensembl:ENSP00000386538 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tb10b_human(display_long)|uniprotkb:TBC1D10B(gene name)|psi-mi:TBC1D10B(display_short)|uniprotkb:Rab27A-GAP-beta(gene name synonym)|uniprotkb:FP2461(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_056342.3|ensembl:ENSG00000169221(gene)|ensembl:ENST00000409939(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000195(RabGAP/TBC)|interpro:IPR035969|reactome:R-HSA-8854214 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:B3iC6bxsYI7npYmPuaRVztl7ytc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H329 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3941680|uniprotkb:Q9H328|uniprotkb:Q5T4G6|uniprotkb:Q5T4G5|uniprotkb:Q9P2V3|ensembl:ENSP00000363694 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:e41lb_human(display_long)|uniprotkb:EPB41L4B(gene name)|psi-mi:EPB41L4B(display_short)|uniprotkb:EHM2(gene name synonym)|uniprotkb:FERM-containing protein CG1(gene name synonym)|uniprotkb:Protein EHM2(gene name synonym)|uniprotkb:LULU2(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 4B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000095203(gene)|ensembl:ENST00000374566(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0042060"(wound healing)|go:"GO:0045177"(apical part of cell)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0051549"(positive regulation of keratinocyte migration)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR030698|interpro:IPR035963|go:"GO:0031032"(actomyosin structure organization)|refseq:NP_060894.2|refseq:NP_061987.3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NSuoD84Y202IDxiauNoP97D55A09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q86V48 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350467|uniprotkb:Q5TH93|uniprotkb:Q8N4X3|uniprotkb:Q8TEH1|ensembl:ENSP00000303758|ensembl:ENSP00000393460 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:luzp1_human(display_long)|uniprotkb:LUZP1(gene name)|psi-mi:LUZP1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001136018.1|refseq:NP_361013.3|refseq:XP_011540392.1|refseq:XP_011540393.1|ensembl:ENSG00000169641(gene)|ensembl:ENST00000302291(transcript)|ensembl:ENST00000418342(transcript)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005634"(nucleus)|go:"GO:0016020"(membrane)|go:"GO:0021503"(neural fold bending)|go:"GO:0060840"(artery development)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026734|mint:Q86V48|refseq:XP_016857741.1|dip:DIP-33113N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:l456S0i3H1z5fv6M4SNkdrls/c49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P26641 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351467|uniprotkb:Q6PJ62|uniprotkb:Q6PK31|uniprotkb:Q96CU2|uniprotkb:Q9P196|intact:EBI-2321928|uniprotkb:B4DTG2|ensembl:ENSP00000331901 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ef1g_human(display_long)|uniprotkb:PRO1608(orf name)|uniprotkb:EEF1G(gene name)|psi-mi:EEF1G(display_short)|uniprotkb:EF1G(gene name synonym)|uniprotkb:eEF-1B gamma(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001395.1|ensembl:ENSG00000254772(gene)|ensembl:ENST00000329251(transcript)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006414"(translational elongation)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001662(Translation elongation factor EF1B, gamma chain, conserved)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR004046(Glutathione S-transferase, C-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR036249|interpro:IPR036282|interpro:IPR036433|interpro:IPR040079|mint:P26641|rcsb pdb:1PBU|rcsb pdb:5DQS|rcsb pdb:5JPO|reactome:R-HSA-156842|dip:DIP-32516N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:biVN96umeEdPm/wvPN4VwbSRHTs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P63244 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-296739|ensembl:ENSP00000426909|uniprotkb:P25388|uniprotkb:P99049|intact:EBI-923003|uniprotkb:B3KTJ0|uniprotkb:Q53HU2|uniprotkb:Q5J8M6|uniprotkb:Q5VLR4|uniprotkb:Q6FH47|intact:EBI-2559282|uniprotkb:D3DWS0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rack1_human(display_long)|uniprotkb:Small ribosomal subunit protein RACK1(gene name synonym)|uniprotkb:HLC7(orf name)|uniprotkb:PIG21(orf name)|uniprotkb:RACK1(gene name)|psi-mi:RACK1(display_short)|uniprotkb:Cell proliferation-inducing gene 21 protein(gene name synonym)|uniprotkb:GNB2L1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-2-like 1(gene name synonym)|uniprotkb:Guanine nucleotide-binding protein subunit beta-like protein 12.3(gene name synonym)|uniprotkb:Human lung cancer oncogene 7 protein(gene name synonym)|uniprotkb:Receptor for activated C kinase(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N rcsb pdb:4AOW|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|mint:P63244|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|ensembl:ENSG00000204628(gene)|ensembl:ENST00000512805(transcript)|go:"GO:0001891"(phagocytic cup)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0007049"(cell cycle)|go:"GO:0007369"(gastrulation)|go:"GO:0008200"(ion channel inhibitor activity)|go:"GO:0008656"(cysteine-type endopeptidase activator activity involved in apoptotic process)|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5626978|rcsb pdb:6ZUO|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0030292"(protein tyrosine kinase inhibitor activity)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030332"(cyclin binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030425"(dendrite)|go:"GO:0030496"(midbody)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0032091"(negative regulation of protein binding)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043022"(ribosome binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0042998"(positive regulation of Golgi to plasma membrane protein transport)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043204"(perikaryon)|go:"GO:0043473"(pigmentation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045879"(negative regulation of smoothened signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048511"(rhythmic process)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051302"(regulation of cell division)|go:"GO:0051343"(positive regulation of cyclic-nucleotide phosphodiesterase activity)|go:"GO:0051434"(BH3 domain binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0051901"(positive regulation of mitochondrial depolarization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071333"(cellular response to glucose stimulus)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0072344"(rescue of stalled ribosome)|go:"GO:1900102"(negative regulation of endoplasmic reticulum unfolded protein response)|go:"GO:1903208"(negative regulation of hydrogen peroxide-induced neuron death)|go:"GO:1990630"(IRE1-RACK1-PP2A complex)|go:"GO:2000114"(regulation of establishment of cell polarity)|go:"GO:2000543"(positive regulation of gastrulation)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001680(WD40 repeat)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR020472|interpro:IPR036322|go:"GO:0060090"(molecular adaptor activity)|refseq:NP_006089.1|dip:DIP-46736N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:LXHlhPtxUzHJNncoPteGw2iXsFg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N4C8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2133481|uniprotkb:Q9P1X1|uniprotkb:Q9P2R8|uniprotkb:D3DTK4|uniprotkb:D3DTK3|uniprotkb:Q5U8Z0|ensembl:ENSP00000347427 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mink1_human(display_long)|uniprotkb:GCK family kinase MiNK(gene name synonym)|uniprotkb:Misshapen/NIK-related kinase(gene name synonym)|uniprotkb:MINK1(gene name)|psi-mi:MINK1(display_short)|uniprotkb:MAP4K6(gene name synonym)|uniprotkb:MINK(gene name synonym)|uniprotkb:Mitogen-activated protein kinase kinase kinase kinase 6(gene name synonym)|uniprotkb:MAPK/ERK kinase kinase kinase 6(gene name synonym)|uniprotkb:B55(gene name synonym)|uniprotkb:YSK2(gene name synonym)|uniprotkb:ZC3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001020108.1|refseq:NP_056531.1|refseq:NP_722549.2|refseq:NP_733763.1|refseq:NP_001308165.1|ensembl:ENSG00000141503(gene)|ensembl:ENST00000355280(transcript)|go:"GO:0000165"(MAPK cascade)|go:"GO:0001952"(regulation of cell-matrix adhesion)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007254"(JNK cascade)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007275"(multicellular organism development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0022407"(regulation of cell-cell adhesion)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900745"(positive regulation of p38MAPK cascade)|go:"GO:2000311"(regulation of AMPA receptor activity)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001180(Citron-like)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q8N4C8|reactome:R-HSA-2559580 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:IkbQUVeJbJ4FN1ZGgAH3LDW/ZcQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5R3F8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-5235725|uniprotkb:Q96PY3|ensembl:ENSP00000385277 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ppr29_human(display_long)|uniprotkb:ELFN2(gene name)|psi-mi:ELFN2(display_short)|uniprotkb:Extracellular leucine-rich repeat and fibronectin type III domain-containing protein 2(gene name synonym)|uniprotkb:KIAA1904(gene name synonym)|uniprotkb:LRRC62(gene name synonym)|uniprotkb:Leucine-rich repeat and fibronectin type-III domain-containing protein 6(gene name synonym)|uniprotkb:Leucine-rich repeat-containing protein 62(gene name synonym)|uniprotkb:PPP1R29(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_443138.2|ensembl:ENSG00000166897(gene)|ensembl:ENST00000402918(transcript)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031012"(extracellular matrix)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:efds3AyUONlxOha9o/NzrG1FZlU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q07960 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-602762|uniprotkb:D3DQQ6|ensembl:ENSP00000310491 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rhg01_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 1(gene name synonym)|uniprotkb:Rho-related small GTPase protein activator(gene name synonym)|uniprotkb:p50-RhoGAP(gene name synonym)|uniprotkb:CDC42 GTPase-activating protein(gene name synonym)|uniprotkb:ARHGAP1(gene name)|psi-mi:ARHGAP1(display_short)|uniprotkb:CDC42GAP(gene name synonym)|uniprotkb:RHOGAP1(gene name synonym)|uniprotkb:GTPase-activating protein rhoGAP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004299.1|refseq:XP_011518397.1|dip:DIP-6081N|ensembl:ENSG00000175220(gene)|ensembl:ENST00000311956(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0010008"(endosome membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0033572"(transferrin transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:2001136"(negative regulation of endocytic recycling)|interpro:IPR000198(RhoGAP)|interpro:IPR001251(Cellular retinaldehyde-binding/triple function, C-terminal)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036865|mint:Q07960|rcsb pdb:1AM4|rcsb pdb:1GRN|rcsb pdb:1OW3|rcsb pdb:1RGP|rcsb pdb:1TX4|rcsb pdb:2NGR|rcsb pdb:5M6X|rcsb pdb:5M70|rcsb pdb:6R3V|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696270 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ceA3oLsnddhLiSbylS89P64mYBo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TBA6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11278147|uniprotkb:O95287|uniprotkb:Q03962|uniprotkb:Q2TS49|uniprotkb:Q9UQQ7|uniprotkb:C9JRU1|ensembl:ENSP00000163416 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:goga5_human(display_long)|uniprotkb:GOLGA5(gene name)|psi-mi:GOLGA5(display_short)|uniprotkb:Cell proliferation-inducing gene 31 protein(gene name synonym)|uniprotkb:Golgin-84(gene name synonym)|uniprotkb:Protein Ret-II(gene name synonym)|uniprotkb:RET-fused gene 5 protein(gene name synonym)|uniprotkb:RETII(gene name synonym)|uniprotkb:RFG5(gene name synonym)|uniprotkb:PIG31(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005104.3|refseq:XP_011535722.1|ensembl:ENSG00000066455(gene)|ensembl:ENST00000163416(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000301"(retrograde transport, vesicle recycling within Golgi)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005801"(cis-Golgi network)|go:"GO:0007030"(Golgi organization)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030133"(transport vesicle)|go:"GO:0031985"(Golgi cisterna)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048193"(Golgi vesicle transport)|interpro:IPR019177|reactome:R-HSA-6811438|go:"GO:0031267"(small GTPase binding) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:PtiO2qhE4u4CFxYqL+bqph4lmT09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P04626 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-641062|ensembl:ENSP00000269571|uniprotkb:Q14256|uniprotkb:Q6LDV1|uniprotkb:Q9UMK4|uniprotkb:B2RZG3|uniprotkb:B4DHN3|uniprotkb:X5D2V5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:erbb2_human(display_long)|uniprotkb:p185erbB2(gene name synonym)|uniprotkb:MLN19(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-2(gene name synonym)|uniprotkb:Tyrosine kinase-type cell surface receptor HER2(gene name synonym)|uniprotkb:Proto-oncogene Neu(gene name synonym)|uniprotkb:ERBB2(gene name)|psi-mi:ERBB2(display_short)|uniprotkb:HER2(gene name synonym)|uniprotkb:NEU(gene name synonym)|uniprotkb:NGL(gene name synonym)|uniprotkb:Metastatic lymph node gene 19 protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N rcsb pdb:4HRN|rcsb pdb:5K33|rcsb pdb:5KWG|rcsb pdb:5MY6|rcsb pdb:5O4G|rcsb pdb:5OB4|rcsb pdb:5TQS|rcsb pdb:6ATT|rcsb pdb:6BGT|rcsb pdb:6J71|rcsb pdb:6LBX|rcsb pdb:6OGE|reactome:R-HSA-1227986|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-1306955|reactome:R-HSA-1358803|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-2219530|reactome:R-HSA-416572|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8863795|reactome:R-HSA-8866910|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045785"(positive regulation of cell adhesion)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048709"(oligodendrocyte differentiation)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|ensembl:ENSG00000141736(gene)|ensembl:ENST00000269571(transcript)|go:"GO:0001042"(RNA polymerase I core binding)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007167"(enzyme linked receptor protein signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007422"(peripheral nervous system development)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0007507"(heart development)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008045"(motor neuron axon guidance)|go:"GO:0008284"(positive regulation of cell population proliferation)|mint:P04626|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1MW4|rcsb pdb:1N8Z|rcsb pdb:1OVC|rcsb pdb:1QR1|rcsb pdb:1S78|rcsb pdb:2A91|rcsb pdb:2JWA|rcsb pdb:2KS1|rcsb pdb:2L4K|rcsb pdb:2N2A|rcsb pdb:3BE1|rcsb pdb:3H3B|rcsb pdb:3MZW|rcsb pdb:3N85|rcsb pdb:3PP0|rcsb pdb:3RCD|rcsb pdb:3WLW|rcsb pdb:3WSQ|rcsb pdb:4GFU|rcsb pdb:4HRL|rcsb pdb:4HRM|go:"GO:0010008"(endosome membrane)|go:"GO:0014065"(phosphatidylinositol 3-kinase signaling)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030182"(neuron differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0032886"(regulation of microtubule-based process)|go:"GO:0033088"(negative regulation of immature T cell proliferation in thymus)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0038143"("ERBB3:ERBB2 complex")|go:"GO:0042060"(wound healing)|go:"GO:0042552"(myelination)|go:"GO:0042802"(identical protein binding)|go:"GO:0043125"(ErbB-3 class receptor binding)|go:"GO:0043209"(myelin sheath)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|refseq:NP_004439.2|dip:DIP-8N|refseq:NP_001005862.1|refseq:NP_001276865.1|refseq:NP_001276867.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6o8GoqTQ64og/aKbzFZZMQ8gRHI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P46940 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UJU6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-751783|uniprotkb:P84070|uniprotkb:Q6IAI8|uniprotkb:Q96F30|uniprotkb:Q96K74|uniprotkb:Q9HBN8|uniprotkb:Q9NR72|uniprotkb:A4D2I9|uniprotkb:B4DEM2|uniprotkb:C9J7P1|uniprotkb:B4DDP6|intact:EBI-28973053|ensembl:ENSP00000411701 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dbnl_human(display_long)|uniprotkb:Drebrin-F(gene name synonym)|uniprotkb:SH3 domain-containing protein 7(gene name synonym)|uniprotkb:Cervical SH3P7(gene name synonym)|uniprotkb:HPK1-interacting protein of 55 kDa(gene name synonym)|uniprotkb:Cervical mucin-associated protein(gene name synonym)|uniprotkb:DBNL(gene name)|psi-mi:DBNL(display_short)|uniprotkb:CMAP(gene name synonym)|uniprotkb:SH3P7(gene name synonym)|uniprotkb:PP5423(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001271242.1|refseq:NP_001271244.1|refseq:NP_001014436.1|refseq:NP_001116428.1|refseq:NP_054782.2|ensembl:ENST00000440166|ensembl:ENSP00000415173|ensembl:ENSP00000411701|ensembl:ENST00000456905|ensembl:ENSP00000416421|ensembl:ENST00000468694|ensembl:ENSP00000417653|ensembl:ENST00000490734|ensembl:ENSP00000417749|ensembl:ENST00000494774|ensembl:ENSP00000419992|ensembl:ENSG00000136279(gene)|ensembl:ENST00000448521(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0002250"(adaptive immune response)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005938"(cell cortex)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0007257"(obsolete activation of JUN kinase activity)|go:"GO:0007416"(synapse assembly)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008047"(enzyme activator activity)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030425"(dendrite)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0043204"(perikaryon)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071800"(podosome assembly)|go:"GO:0097178"(ruffle assembly)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR029006|interpro:IPR029923|interpro:IPR035717|interpro:IPR036028|mint:Q9UJU6|rcsb pdb:1X67|reactome:R-HSA-264870|reactome:R-HSA-6794361|reactome:R-HSA-6798695 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:OOa7vGOHVCiCKA9Wt0YUYGR5cu09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TD55 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2563808|uniprotkb:Q8WYS8|uniprotkb:Q7L4H4|ensembl:ENSP00000326706 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkho2_human(display_long)|uniprotkb:PLEKHQ1(gene name synonym)|uniprotkb:Pleckstrin homology domain-containing family Q member 1(gene name synonym)|uniprotkb:PP9099(orf name)|uniprotkb:PLEKHO2(gene name)|psi-mi:PLEKHO2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001181988.1|refseq:NP_079477.2|ensembl:ENSG00000241839(gene)|ensembl:ENST00000323544(transcript)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR043448|reactome:R-HSA-6798695|go:"GO:0005576"(extracellular region) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yujWSnifK9kpsjJ7GpHQD/OtNvg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BU76 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-742459|uniprotkb:Q6P5Y0|uniprotkb:Q6ZTZ6|uniprotkb:Q6ZWA6|uniprotkb:Q8IZH3|ensembl:ENSP00000272139 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mmta2_human(display_long)|uniprotkb:MMTAG2(gene name)|psi-mi:MMTAG2(display_short)|uniprotkb:C1orf35(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_077295.1|mint:Q9BU76|reactome:R-HSA-6798695|ensembl:ENSG00000143793(gene)|ensembl:ENST00000272139(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0034774"(secretory granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019315|interpro:IPR039207 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:TwnLhBYwwR6yPCw3sd7g/sPHJd09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TE77 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-8743776|uniprotkb:Q6PK42|uniprotkb:Q76I75|uniprotkb:Q8N9L8|uniprotkb:Q8WYL0|uniprotkb:Q9NV45|uniprotkb:Q9NWZ7|ensembl:ENSP00000312081 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ssh3_human(display_long)|uniprotkb:SSH3(gene name)|psi-mi:SSH3(display_short)|uniprotkb:SSH-like protein 3(gene name synonym)|uniprotkb:SSH3L(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060327.3|ensembl:ENSG00000172830(gene)|ensembl:ENST00000308127(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0004725"(protein tyrosine phosphatase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008138"(protein tyrosine/serine/threonine phosphatase activity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0106306"|go:"GO:0106307"|interpro:IPR000340(Protein-tyrosine phosphatase, dual specificity)|interpro:IPR000387(Protein-tyrosine phosphatase)|interpro:IPR014876(DEK C terminal)|interpro:IPR016130(Protein-tyrosine phosphatase, active site)|interpro:IPR020422|interpro:IPR029021|interpro:IPR043587|interpro:IPR043588 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Y2d7VMEhA7EA8OOnkEPDLwc48i49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75955 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-603643|ensembl:ENSP00000365569|ensembl:ENSP00000372873|ensembl:ENSP00000373056|ensembl:ENSP00000388861|ensembl:ENSP00000391438|uniprotkb:Q969J8|uniprotkb:Q9UHW1|uniprotkb:Q9UNV8|uniprotkb:B4DVY7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:flot1_human(display_long)|uniprotkb:FLOT1(gene name)|psi-mi:FLOT1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0001931"(uropod)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0001765"(membrane raft assembly)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016600"(flotillin complex)|go:"GO:0022617"(extracellular matrix disassembly)|go:"GO:0030027"(lamellipodium)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032226"(positive regulation of synaptic transmission, dopaminergic)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0033227"(dsRNA transport)|go:"GO:0034116"(positive regulation of heterotypic cell-cell adhesion)|go:"GO:0034141"(positive regulation of toll-like receptor 3 signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0035255"(ionotropic glutamate receptor binding)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044854"(plasma membrane raft assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050821"(protein stabilization)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051580"(regulation of neurotransmitter uptake)|go:"GO:0060355"(positive regulation of cell adhesion molecule production)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070528"(protein kinase C signaling)|go:"GO:0071360"(cellular response to exogenous dsRNA)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098691"(dopaminergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0098982"(GABA-ergic synapse)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1901890"(positive regulation of cell junction assembly)|go:"GO:1903044"(protein localization to membrane raft)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR001107(Band 7 protein)|interpro:IPR027705|interpro:IPR036013|mint:O75955|reactome:R-HSA-5213460|reactome:R-HSA-5675482|reactome:R-HSA-8849932|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000137312(gene)|ensembl:ENSG00000206379(gene)|ensembl:ENSG00000206480(gene)|ensembl:ENSG00000230143(gene)|ensembl:ENSG00000232280(gene)|ensembl:ENST00000376389(transcript)|ensembl:ENST00000383382(transcript)|ensembl:ENST00000383562(transcript)|ensembl:ENST00000436822(transcript)|ensembl:ENST00000444632(transcript)|refseq:NP_005794.1|refseq:NP_001305804.1|refseq:XP_005248837.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:wRw9QYIRNJb0ZQtwjm/D+ydci8k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7Z699 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-5235340|uniprotkb:B2RPJ8|uniprotkb:Q05D53|uniprotkb:Q8N256|ensembl:ENSP00000299084 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:spre1_human(display_long)|uniprotkb:SPRED1(gene name)|psi-mi:SPRED1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_689807.1|ensembl:ENSG00000166068(gene)|ensembl:ENST00000299084(transcript)|go:"GO:0000188"(obsolete inactivation of MAPK activity)|go:"GO:0005173"(stem cell factor receptor binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0043409"(negative regulation of MAPK cascade)|go:"GO:0043517"(positive regulation of DNA damage response, signal transduction by p53 class mediator)|go:"GO:0060979"(vasculogenesis involved in coronary vascular morphogenesis)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090051"(negative regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090311"(regulation of protein deacetylation)|go:"GO:1902747"(negative regulation of lens fiber cell differentiation)|interpro:IPR000697(EVH1)|interpro:IPR007875(Sprouty)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR023337|interpro:IPR041937|mint:Q7Z699|rcsb pdb:3SYX|rcsb pdb:6V65|rcsb pdb:6V6F|reactome:R-HSA-5658442|reactome:R-HSA-5658623|reactome:R-HSA-6802953 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+jGnxx5TP0aeldLkqVGfO8uY2ko9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P31946 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-359815|uniprotkb:A8K9K2|uniprotkb:E1P616|ensembl:ENSP00000300161|ensembl:ENSP00000361930 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:1433b_human(display_long)|uniprotkb:YWHAB(gene name)|psi-mi:YWHAB(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym)|uniprotkb:Protein 1054(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003395.1|refseq:NP_647539.1|go:"GO:0050815"(phosphoserine residue binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|mint:P31946|rcsb pdb:2BQ0|rcsb pdb:2C23|rcsb pdb:4DNK|rcsb pdb:5N10|rcsb pdb:6A5Q|rcsb pdb:6BYK|rcsb pdb:6GN0|rcsb pdb:6GN8|rcsb pdb:6GNJ|rcsb pdb:6GNK|rcsb pdb:6GNN|rcsb pdb:6HEP|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-165159|reactome:R-HSA-166208|reactome:R-HSA-170968|reactome:R-HSA-170984|reactome:R-HSA-2028269|reactome:R-HSA-392517|reactome:R-HSA-450385|reactome:R-HSA-450513|reactome:R-HSA-5625740|reactome:R-HSA-5628897|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-75035|reactome:R-HSA-9614399|reactome:R-HSA-9649948|reactome:R-HSA-9656223|reactome:R-HSA-9660537|ensembl:ENSG00000166913(gene)|ensembl:ENST00000353703(transcript)|ensembl:ENST00000372839(transcript)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005774"(vacuolar membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006605"(protein targeting)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0035308"(negative regulation of protein dephosphorylation)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0042826"(histone deacetylase binding)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045744"(negative regulation of G protein-coupled receptor signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:XP_016883528.1|dip:DIP-743N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:rp43CodPzsPadWEPtbnpKFAVIIU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15691 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1004115|uniprotkb:Q3KQS8|uniprotkb:B2R6I7|uniprotkb:E1P5M8|ensembl:ENSP00000364721 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mare1_human(display_long)|uniprotkb:APC-binding protein EB1(gene name synonym)|uniprotkb:End-binding protein 1(gene name synonym)|uniprotkb:MAPRE1(gene name)|psi-mi:MAPRE1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_036457.1|refseq:XP_011526998.1|ensembl:ENSG00000101367(gene)|ensembl:ENST00000375571(transcript)|go:"GO:0001578"(microtubule bundle formation)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005813"(centrosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005881"(cytoplasmic microtubule)|go:"GO:0005925"(focal adhesion)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008104"(protein localization)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0035372"(protein localization to microtubule)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046785"(microtubule polymerization)|go:"GO:0016477"(cell migration)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:0051225"(spindle assembly)|go:"GO:0019901"(protein kinase binding)|go:"GO:0051233"(spindle midzone)|go:"GO:0051301"(cell division)|go:"GO:0071539"(protein localization to centrosome)|go:"GO:0030981"(cortical microtubule cytoskeleton)|go:"GO:1903033"(positive regulation of microtubule plus-end binding)|go:"GO:0031110"(regulation of microtubule polymerization or depolymerization)|go:"GO:1904825"(protein localization to microtubule plus-end)|go:"GO:1905515"(non-motile cilium assembly)|go:"GO:1905721"(mitotic spindle astral microtubule end)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0031115"(negative regulation of microtubule polymerization)|interpro:IPR004953(EB1, C-terminal)|interpro:IPR027328|interpro:IPR027739|interpro:IPR036133|interpro:IPR036872|mint:Q15691|rcsb pdb:1PA7|rcsb pdb:1TXQ|rcsb pdb:1UEG|rcsb pdb:1VKA|rcsb pdb:1WU9|rcsb pdb:1YIB|rcsb pdb:1YIG|rcsb pdb:2HKQ|rcsb pdb:2HL3|rcsb pdb:2HL5|rcsb pdb:2QJZ|rcsb pdb:2R8U|rcsb pdb:3GJO|rcsb pdb:3MTU|rcsb pdb:3MUD|rcsb pdb:3TQ7|rcsb pdb:4XA1|rcsb pdb:4XA3|rcsb pdb:4XA6|rcsb pdb:5JV3|rcsb pdb:5JVM|rcsb pdb:5JVP|rcsb pdb:5JVR|rcsb pdb:5JVS|rcsb pdb:5JVU|rcsb pdb:5JX1|rcsb pdb:5WLQ|rcsb pdb:6PF2|rcsb pdb:6PFP|rcsb pdb:6YF5|rcsb pdb:6YSH|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-8852276|reactome:R-HSA-8854518|reactome:R-HSA-9648025|dip:DIP-38018N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+JBCBM7dbbrxn6mX8RiwejYWJ2U9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6NYC8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2557469|uniprotkb:A8MSS7|uniprotkb:Q8NDQ4|uniprotkb:A2AIB8|uniprotkb:Q9BRL9|uniprotkb:B7ZCV7|uniprotkb:Q8TF52|uniprotkb:Q6ZUJ6|uniprotkb:Q68CK8|uniprotkb:A4UBI6|uniprotkb:A6NCB7|uniprotkb:A2AB01|uniprotkb:Q6ZTV1|ensembl:ENSP00000274853|ensembl:ENSP00000373067|ensembl:ENSP00000382150|ensembl:ENSP00000383400|ensembl:ENSP00000388790|ensembl:ENSP00000400129|ensembl:ENSP00000400990|ensembl:ENSP00000404066|ensembl:ENSP00000405234|ensembl:ENSP00000412456|ensembl:ENSP00000413596|ensembl:ENSP00000416648|ensembl:ENSP00000480270 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ppr18_human(display_long)|uniprotkb:PPP1R18(gene name)|psi-mi:PPP1R18(display_short)|uniprotkb:HKMT1098(gene name synonym)|uniprotkb:KIAA1949(gene name synonym)|uniprotkb:Protein phosphatase 1 F-actin cytoskeleton-targeting subunit(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 18(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001128342.1|refseq:NP_597728.1|ensembl:ENSG00000146112(gene)|ensembl:ENSG00000206485(gene)|ensembl:ENSG00000225060(gene)|ensembl:ENSG00000229998(gene)|ensembl:ENST00000274853(transcript)|ensembl:ENST00000383573(transcript)|ensembl:ENST00000399199(transcript)|ensembl:ENST00000400554(transcript)|ensembl:ENST00000437121(transcript)|ensembl:ENST00000438815(transcript)|ensembl:ENST00000438945(transcript)|ensembl:ENSG00000230341(gene)|ensembl:ENST00000443517(transcript)|ensembl:ENSG00000234000(gene)|ensembl:ENST00000444206(transcript)|ensembl:ENST00000449705(transcript)|ensembl:ENST00000451544(transcript)|ensembl:ENST00000455935(transcript)|ensembl:ENST00000615527(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0019902"(phosphatase binding)|interpro:IPR025903|interpro:IPR025907|interpro:IPR026671|mint:Q6NYC8 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:63zpNZuwQb7VD0pOrr6yaRpPNmA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T5P2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-746898|uniprotkb:A5LHW9|uniprotkb:A6PVQ5|uniprotkb:A6PVQ6|uniprotkb:A6PVQ7|uniprotkb:Q5T5P3|uniprotkb:Q4KMG4|uniprotkb:Q5T7H3|uniprotkb:Q6MZZ6|uniprotkb:Q6ZUI4|uniprotkb:Q8WV45|uniprotkb:Q9NSR2|uniprotkb:Q9ULK3|ensembl:ENSP00000365637|uniprotkb:A6NLF3|uniprotkb:B9EGK4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:skt_human(display_long)|uniprotkb:KIAA1217(gene name)|psi-mi:KIAA1217(display_short)|uniprotkb:SKT(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001091970.1|refseq:NP_001269696.1|refseq:NP_001269697.1|refseq:NP_001269698.1|refseq:NP_001269699.1|refseq:NP_062536.2|refseq:XP_016871918.1|ensembl:ENSG00000120549(gene)|ensembl:ENST00000376454(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR022782|interpro:IPR026725|refseq:XP_005252573.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3rlNZUWLC4c0hvktiGEo55Sj15Q9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13177 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1045887|uniprotkb:Q13154|uniprotkb:Q6ISC3|ensembl:ENSP00000314067|intact:EBI-28976120 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pak2_human(display_long)|uniprotkb:p21-activated kinase 2(gene name synonym)|uniprotkb:Gamma-PAK(gene name synonym)|uniprotkb:PAK65(gene name synonym)|uniprotkb:S6/H4 kinase(gene name synonym)|uniprotkb:p58(gene name synonym)|uniprotkb:PAK2(gene name)|psi-mi:PAK2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000314067|ensembl:ENSG00000180370(gene)|ensembl:ENST00000327134(transcript)|go:"GO:0002223"(stimulatory C-type lectin receptor signaling pathway)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016310"(phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0040008"(regulation of growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048010"(vascular endothelial growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050731"(positive regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060996"(dendritic spine development)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0071407"(cellular response to organic cyclic compound)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001271"(negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035064|interpro:IPR035065|interpro:IPR036936|mint:Q13177|rcsb pdb:3PCS|reactome:R-HSA-164944|reactome:R-HSA-202433|reactome:R-HSA-211728|reactome:R-HSA-211733|reactome:R-HSA-211736|reactome:R-HSA-2871796|reactome:R-HSA-389359|reactome:R-HSA-3928664|reactome:R-HSA-399954|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-445355|reactome:R-HSA-5621575|reactome:R-HSA-5627123|reactome:R-HSA-5687128|reactome:R-HSA-8950505|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-5218920|refseq:NP_002568.2|refseq:XP_011511172.1|refseq:XP_016861990.1|dip:DIP-38249N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:BLFG1UZy6GUy26Hd7VDehsIq3/I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:A6NDB9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-6873185|intact:EBI-28977450|ensembl:ENSP00000344996|ensembl:ENSP00000500424 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:palm3_human(display_long)|uniprotkb:PALM3(gene name)|psi-mi:PALM3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000344996|ensembl:ENSP00000500424|ensembl:ENSG00000187867(gene)|ensembl:ENSG00000288318(gene)|ensembl:ENST00000340790(transcript)|ensembl:ENST00000672551(transcript)|go:"GO:0001960"(negative regulation of cytokine-mediated signaling pathway)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0008063"(Toll signaling pathway)|go:"GO:0032496"(response to lipopolysaccharide)|interpro:IPR024149|refseq:NP_001138500.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:PzFwi9b2OsyYZVc5nVVWWCFiBvY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15208 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-458376|ensembl:ENSP00000229812|uniprotkb:Q503A1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stk38_human(display_long)|uniprotkb:NDR1(gene name synonym)|uniprotkb:STK38(gene name)|psi-mi:STK38(display_short)|uniprotkb:NDR1 protein kinase(gene name synonym)|uniprotkb:Nuclear Dbf2-related kinase 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000112079(gene)|ensembl:ENST00000229812(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006464"(cellular protein modification process)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR000961(Protein kinase, C-terminal)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR017892|mint:Q15208|rcsb pdb:1PSB|rcsb pdb:6BXI|reactome:R-HSA-9013418|reactome:R-HSA-9013422|refseq:NP_009202.1|refseq:XP_006715051.1|refseq:XP_006715052.1|refseq:NP_001292031.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:YHzdDrPEH6YdhOXtcnLWArqftck9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WTV0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-78657|uniprotkb:Q52LZ5|uniprotkb:Q14016|uniprotkb:Q6KFX4|ensembl:ENSP00000414979|uniprotkb:F8W8N0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:scrb1_human(display_long)|uniprotkb:SCARB1(gene name)|psi-mi:SCARB1(display_short)|uniprotkb:CD36L1(gene name synonym)|uniprotkb:CLA1(gene name synonym)|uniprotkb:SR-BI(gene name synonym)|uniprotkb:CD36 antigen-like 1(gene name synonym)|uniprotkb:CD36 and LIMPII analogous 1(gene name synonym)|uniprotkb:Collagen type I receptor, thrombospondin receptor-like 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005496.4|ensembl:ENSG00000073060(gene)|ensembl:ENST00000415380(transcript)|go:"GO:0001530"(lipopolysaccharide binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0001875"(lipopolysaccharide immune receptor activity)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0005044"(scavenger receptor activity)|go:"GO:0005215"(transporter activity)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006702"(androgen biosynthetic process)|go:"GO:0006707"(cholesterol catabolic process)|go:"GO:0008035"(high-density lipoprotein particle binding)|go:"GO:0008289"(lipid binding)|go:"GO:0009986"(cell surface)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0010867"(positive regulation of triglyceride biosynthetic process)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010899"(regulation of phosphatidylcholine catabolic process)|go:"GO:0015914"(phospholipid transport)|go:"GO:0015920"(lipopolysaccharide transport)|go:"GO:0030169"(low-density lipoprotein particle binding)|go:"GO:0030666"(endocytic vesicle membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0032497"(detection of lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034185"(apolipoprotein binding)|go:"GO:0034186"(apolipoprotein A-I binding)|go:"GO:0034375"(high-density lipoprotein particle remodeling)|go:"GO:0034381"(plasma lipoprotein particle clearance)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0034384"(high-density lipoprotein particle clearance)|go:"GO:0035461"(vitamin transmembrane transport)|go:"GO:0042060"(wound healing)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0043654"(recognition of apoptotic cell)|go:"GO:0043691"(reverse cholesterol transport)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051000"(positive regulation of nitric-oxide synthase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070328"(triglyceride homeostasis)|go:"GO:0070506"(high-density lipoprotein particle receptor activity)|go:"GO:0070508"(cholesterol import)|interpro:IPR002159(CD36 antigen)|interpro:IPR005428(Adhesion molecule CD36)|reactome:R-HSA-3000471|reactome:R-HSA-8964011|refseq:NP_001076428.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:En6dno+bRV4EB8FC539pcRRMIvs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P13639 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-352560|uniprotkb:Q58J86|uniprotkb:B2RMP5|uniprotkb:D6W618|ensembl:ENSP00000307940 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ef2_human(display_long)|uniprotkb:EEF2(gene name)|psi-mi:EEF2(display_short)|uniprotkb:EF2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001952.1|ensembl:ENSG00000167658(gene)|ensembl:ENST00000309311(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0002931"(response to ischemia)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0003723"(RNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006414"(translational elongation)|go:"GO:0007568"(aging)|go:"GO:0008097"(5S rRNA binding)|go:"GO:0014009"(glial cell proliferation)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0019901"(protein kinase binding)|go:"GO:0032355"(response to estradiol)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0043022"(ribosome binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0051015"(actin filament binding)|go:"GO:0051593"(response to folic acid)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990416"(cellular response to brain-derived neurotrophic factor stimulus)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR000640(Translation elongation factor EFG/EF2, C-terminal)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR005517(Translation elongation factor EFG/EF2, domain IV)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|interpro:IPR020568|interpro:IPR027417|interpro:IPR031157|interpro:IPR035647|interpro:IPR041095|mint:P13639|rcsb pdb:4V6X|rcsb pdb:6D9J|rcsb pdb:6Z6M|rcsb pdb:6Z6N|reactome:R-HSA-156902|reactome:R-HSA-5336415|reactome:R-HSA-5358493|reactome:R-HSA-6798695|reactome:R-HSA-8876725 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:US1dzGQ5V1oBXVtYeGt5H3HCIr09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14C86 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1049788|intact:EBI-1384220|intact:EBI-2654427|uniprotkb:Q8ND92|uniprotkb:Q9P207|uniprotkb:Q9Y4N0|uniprotkb:A8MYK3|uniprotkb:Q14C76|uniprotkb:Q2Q1W1|uniprotkb:Q8WU86|uniprotkb:Q96CZ4|uniprotkb:Q9NXQ1|uniprotkb:B0QZ62|uniprotkb:B0QZ63|uniprotkb:B0QZ64|intact:EBI-2558352|ensembl:ENSP00000377664|ensembl:ENSP00000419063 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gapd1_human(display_long)|uniprotkb:GAPVD1(gene name)|psi-mi:GAPVD1(display_short)|uniprotkb:GAPEX5(gene name synonym)|uniprotkb:KIAA1521(gene name synonym)|uniprotkb:RAP6(gene name synonym)|uniprotkb:Rab5-activating protein 6(gene name synonym)|uniprotkb:GAPex-5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001269608.1|refseq:NP_001269609.1|refseq:NP_001269610.1|refseq:NP_001317707.1|refseq:XP_016870095.1|refseq:XP_016870096.1|refseq:XP_016870097.1|refseq:NP_056450.2|refseq:XP_016870098.1|refseq:XP_005251961.1|ensembl:ENSG00000165219(gene)|ensembl:ENST00000394104(transcript)|ensembl:ENST00000495955(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0007165"(signal transduction)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0051223"(regulation of protein transport)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR003123(Vacuolar sorting protein 9)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR037191|interpro:IPR041545|mint:Q14C86|reactome:R-HSA-8856828|reactome:R-HSA-8876198|refseq:XP_006717107.1|refseq:XP_005251958.1|refseq:XP_016870090.1|refseq:XP_016870091.1|refseq:XP_016870092.1|refseq:XP_016870093.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:SX6gvb2Odit7L3I+Dtc5ub+qixE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5TCQ9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-310506|uniprotkb:Q5TCR0|uniprotkb:Q9H2V6|uniprotkb:Q5TCQ8|uniprotkb:Q9H5Y8|uniprotkb:Q9HBC4|intact:EBI-2512710|intact:EBI-991068|ensembl:ENSP00000304604|uniprotkb:Q9HCD8|uniprotkb:A0A024R0E9|uniprotkb:A0A024R0H3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:magi3_human(display_long)|uniprotkb:MAGI3(gene name)|psi-mi:MAGI3(display_short)|uniprotkb:KIAA1634(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000307546(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|ensembl:ENSG00000081026(gene)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030054"(cell junction)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0016020"(membrane)|go:"GO:0060090"(molecular adaptor activity)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR027417|interpro:IPR030035|interpro:IPR036020|interpro:IPR036034|mint:Q5TCQ9|rcsb pdb:3SOE|refseq:NP_001136254.1|refseq:NP_690864.2|refseq:XP_005270794.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:muK+zH3ww4Ve8aJ74iU2be8hRa09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9C0D5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11023211|uniprotkb:C9JD88|uniprotkb:Q49AI8|ensembl:ENSP00000263635 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tanc1_human(display_long)|uniprotkb:TANC1(gene name)|psi-mi:TANC1(display_short)|uniprotkb:KIAA1728(gene name synonym)|uniprotkb:Tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001139381.1|refseq:NP_203752.2|refseq:XP_006712873.1|refseq:XP_011510360.1|ensembl:ENSG00000115183(gene)|ensembl:ENST00000263635(transcript)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008542"(visual learning)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030425"(dendrite)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043679"(axon terminus)|go:"GO:0097062"(dendritic spine maintenance)|interpro:IPR002110(Ankyrin)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR019734|interpro:IPR020683|interpro:IPR036770 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:V9W0CRzcZBfeOuZF/zUlWd9k+Ak9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75369 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-352089|intact:EBI-1754974|uniprotkb:Q13706|uniprotkb:Q59EC2|uniprotkb:Q6MZJ1|uniprotkb:Q8WXS9|uniprotkb:Q8WXT0|uniprotkb:Q8WXT1|uniprotkb:Q8WXT2|uniprotkb:Q9NRB5|uniprotkb:B2ZZ84|uniprotkb:Q9NT26|uniprotkb:Q9UEV9|intact:EBI-1960054|uniprotkb:C9JKE6|uniprotkb:B2ZZ85|uniprotkb:C9JMC4|ensembl:ENSP00000295956|uniprotkb:B2ZZ83|uniprotkb:Q60FE7|uniprotkb:Q8WXT3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:flnb_human(display_long)|uniprotkb:FLNB(gene name)|psi-mi:FLNB(display_short)|uniprotkb:FLN1L(gene name synonym)|uniprotkb:FLN3(gene name synonym)|uniprotkb:TABP(gene name synonym)|uniprotkb:TAP(gene name synonym)|uniprotkb:Beta-filamin(gene name synonym)|uniprotkb:Actin-binding-like protein(gene name synonym)|uniprotkb:Thyroid autoantigen(gene name synonym)|uniprotkb:Truncated actin-binding protein(gene name synonym)|uniprotkb:ABP-280 homolog(gene name synonym)|uniprotkb:ABP-278(gene name synonym)|uniprotkb:Filamin-3(gene name synonym)|uniprotkb:Filamin homolog 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001157791.1|refseq:NP_001448.2|go:"GO:0003334"(keratinocyte development)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007165"(signal transduction)|go:"GO:0007519"(skeletal muscle tissue development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR029874|interpro:IPR036872|interpro:IPR044801|mint:O75369|rcsb pdb:2DI8|rcsb pdb:2DI9|rcsb pdb:2DIA|rcsb pdb:2DIB|rcsb pdb:2DIC|rcsb pdb:2DJ4|rcsb pdb:2DLG|rcsb pdb:2DMB|rcsb pdb:2DMC|rcsb pdb:2E9I|rcsb pdb:2E9J|rcsb pdb:2EE6|rcsb pdb:2EE9|rcsb pdb:2EEA|rcsb pdb:2EEB|rcsb pdb:2EEC|rcsb pdb:2EED|rcsb pdb:2WA5|rcsb pdb:2WA6|rcsb pdb:2WA7|rcsb pdb:3FER|rcsb pdb:4B7L|rcsb pdb:5DCP|reactome:R-HSA-1169408|ensembl:ENSG00000136068(gene)|ensembl:ENST00000295956(transcript)|go:"GO:0001725"(stress fiber)|refseq:NP_001157789.1|refseq:NP_001157790.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lsf6C/Vg0io7UhUi1Kapgwp0p5E9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35613 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-750709|uniprotkb:Q7Z796|uniprotkb:Q8IZL7|intact:EBI-2553051|uniprotkb:A6NJW1|uniprotkb:D3YLG5|ensembl:ENSP00000333769 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:basi_human(display_long)|uniprotkb:Leukocyte activation antigen M6(gene name synonym)|uniprotkb:Collagenase stimulatory factor(gene name synonym)|uniprotkb:Extracellular matrix metalloproteinase inducer(gene name synonym)|uniprotkb:5F7(gene name synonym)|uniprotkb:Tumor cell-derived collagenase stimulatory factor(gene name synonym)|uniprotkb:OK blood group antigen(gene name synonym)|uniprotkb:BSG(gene name)|psi-mi:BSG(display_short)|uniprotkb:UNQ6505/PRO21383(orf name)|uniprotkb:Hepatoma-associated antigen(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001719.2|refseq:NP_940991.1|refseq:NP_940993.1|refseq:NP_001309172.1|refseq:NP_940992.1|refseq:XP_016882662.1|dip:DIP-50310N|ensembl:ENSG00000172270(gene)|ensembl:ENST00000333511(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001525"(angiogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001750"(photoreceptor outer segment)|go:"GO:0001917"(photoreceptor inner segment)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0003407"(neural retina development)|go:"GO:0005537"(mannose binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007411"(axon guidance)|go:"GO:0007566"(embryo implantation)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010595"(positive regulation of endothelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030424"(axon)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0032755"(positive regulation of interleukin-6 production)|go:"GO:0038023"(signaling receptor activity)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0046598"(positive regulation of viral entry into host cell)|go:"GO:0046689"(response to mercury ion)|go:"GO:0046697"(decidualization)|go:"GO:0051591"(response to cAMP)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070593"(dendrite self-avoidance)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098632"(cell-cell adhesion mediator activity)|go:"GO:1904466"(positive regulation of matrix metallopeptidase secretion)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR043204|interpro:IPR044157|mint:P35613|rcsb pdb:3B5H|rcsb pdb:3I84|rcsb pdb:3I85|rcsb pdb:3QQN|rcsb pdb:4U0Q|rcsb pdb:5X0T|rcsb pdb:5XF0|rcsb pdb:6LYY|rcsb pdb:6LZ0|rcsb pdb:7CKO|rcsb pdb:7CKR|rcsb pdb:7DA5|reactome:R-HSA-1474228|reactome:R-HSA-210991|reactome:R-HSA-216083|reactome:R-HSA-433692|reactome:R-HSA-5619070|reactome:R-HSA-70268|rcsb pdb:3QR2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:jVbDR+TKBzTjXoxR4At6XQg59ZA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O14908 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-373132|uniprotkb:Q9BTC9|uniprotkb:A8MZG3|uniprotkb:A8K4I3|ensembl:ENSP00000340698|ensembl:ENSP00000376753|ensembl:ENSP00000466747 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gipc1_human(display_long)|uniprotkb:C19orf3(gene name synonym)|uniprotkb:GIPC(gene name synonym)|uniprotkb:GIPC1(gene name)|psi-mi:GIPC1(display_short)|uniprotkb:RGS19IP1(gene name synonym)|uniprotkb:RGS19-interacting protein 1(gene name synonym)|uniprotkb:GAIP C-terminus-interacting protein(gene name synonym)|uniprotkb:RGS-GAIP-interacting protein(gene name synonym)|uniprotkb:Tax interaction protein 2(gene name synonym)|uniprotkb:Synectin(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005707.1|refseq:NP_974197.1|refseq:NP_974199.1|refseq:NP_974198.1|refseq:NP_974223.1|ensembl:ENSG00000123159(gene)|ensembl:ENST00000345425(transcript)|ensembl:ENST00000393033(transcript)|ensembl:ENST00000586027(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005903"(brush border)|go:"GO:0005938"(cell cortex)|go:"GO:0006605"(protein targeting)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0012506"(vesicle membrane)|go:"GO:0014047"(glutamate secretion)|go:"GO:0016020"(membrane)|go:"GO:0017022"(myosin binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030511"(positive regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0032435"(negative regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043197"(dendritic spine)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0048023"(positive regulation of melanin biosynthetic process)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:2000300"(regulation of synaptic vesicle exocytosis)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR017379(Uncharacterised conserved protein UCP038083, PDZ)|interpro:IPR036034|refseq:XP_016881636.1|refseq:XP_016881637.1|dip:DIP-31142N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3lbsiL3bZ/h3ISEr/ryTN7FgbQI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9P2M7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-79537|intact:EBI-28986579|ensembl:ENSP00000271636|uniprotkb:Q5T386|uniprotkb:Q9NR25|uniprotkb:A6H8L3|uniprotkb:A7MD22 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cing_human(display_long)|uniprotkb:CGN(gene name)|psi-mi:CGN(display_short)|uniprotkb:KIAA1319(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000143375(gene)|ensembl:ENST00000271636(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0016459"(myosin complex)|go:"GO:0030054"(cell junction)|go:"GO:0045296"(cadherin binding)|interpro:IPR002928(Myosin tail)|mint:Q9P2M7|reactome:R-HSA-2173791|refseq:NP_065821.1|ensembl:ENSP00000271636|refseq:XP_005245422.1|dip:DIP-30947N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RJ4soprXOGUAlMLVIikuoeMs3v09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15019 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-741220|intact:EBI-28986019|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENSP00000385172|uniprotkb:Q14132|uniprotkb:Q8IUK9|uniprotkb:Q96CB0|uniprotkb:B4DGE8|uniprotkb:Q53QU3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sept2_human(display_long)|uniprotkb:SEPTIN2(gene name)|psi-mi:SEPTIN2(display_short)|uniprotkb:DIFF6(gene name synonym)|uniprotkb:KIAA0158(gene name synonym)|uniprotkb:NEDD5(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 5(gene name synonym)|uniprotkb:SEPT2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001269901.1|refseq:NP_001269902.1|ensembl:ENSG00000168385(gene)|ensembl:ENST00000360051(transcript)|ensembl:ENST00000391971(transcript)|ensembl:ENST00000391973(transcript)|ensembl:ENST00000402092(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000776"(kinetochore)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005886"(plasma membrane)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007224"(smoothened signaling pathway)|go:"GO:0007283"(spermatogenesis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0017157"(regulation of exocytosis)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0031175"(neuron projection development)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060170"(ciliary membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|interpro:IPR008113(Septin 2)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|mint:Q15019|rcsb pdb:2QA5|rcsb pdb:2QAG|rcsb pdb:2QNR|rcsb pdb:6UPA|rcsb pdb:6UPQ|rcsb pdb:6UPR|reactome:R-HSA-5620912|refseq:NP_001008491.1|refseq:NP_001008492.1|refseq:NP_004395.1|refseq:NP_006146.1|refseq:XP_016859694.1|refseq:XP_016859695.1|refseq:NP_001307958.1|refseq:NP_001307959.1|refseq:NP_001307960.1|refseq:NP_001307961.1|refseq:NP_001307962.1|refseq:NP_001307963.1|refseq:NP_001307964.1|ensembl:ENSP00000353157|ensembl:ENSP00000375832|ensembl:ENSP00000375834|ensembl:ENST00000401990|ensembl:ENSP00000385109|ensembl:ENSP00000385172|ensembl:ENST00000616972|ensembl:ENSP00000479861|dip:DIP-38220N - - crc64:12CCBBE30806F92F figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:H0Us8GtPe2XuXlOYXC0DX79kB/49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6P995 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3916634|uniprotkb:Q8WYR8|uniprotkb:Q8N970|uniprotkb:Q8N3K1|uniprotkb:Q8TF55|uniprotkb:Q8N1Y4|uniprotkb:Q8NB81|uniprotkb:Q53SK3|ensembl:ENSP00000304108 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:f171b_human(display_long)|uniprotkb:FAM171B(gene name)|psi-mi:FAM171B(display_short)|uniprotkb:KIAA1946(gene name synonym)|uniprotkb:NPD019(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_803237.3|ensembl:ENSG00000144369(gene)|ensembl:ENST00000304698(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR018890 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:khdWGder6phnnssGskXHCoWX4e09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15149 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-297903|intact:EBI-1103289|intact:EBI-1103265|intact:EBI-1055056|uniprotkb:Q15148|uniprotkb:Q16640|ensembl:ENSP00000323856|uniprotkb:Q6S376|intact:EBI-28976159|uniprotkb:Q6S380|intact:EBI-1103313|uniprotkb:Q6S377|uniprotkb:Q6S378|uniprotkb:Q6S379|intact:EBI-1103301|intact:EBI-1103253|uniprotkb:Q6S381|uniprotkb:Q6S382|uniprotkb:Q6S383|intact:EBI-2825763 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:plec_human(display_long)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:PLEC1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031668"(cellular response to extracellular stimulus)|go:"GO:0032094"(response to food)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0034332"(adherens junction organization)|go:"GO:0034613"(cellular protein localization)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042060"(wound healing)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043114"(regulation of vascular permeability)|go:"GO:0043209"(myelin sheath)|go:"GO:0043621"(protein self-association)|go:"GO:0043933"(protein-containing complex organization)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045109"(intermediate filament organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0022904"(respiratory electron transport chain)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045445"(myoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0002522"(leukocyte migration involved in immune response)|go:"GO:0003334"(keratinocyte development)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070584"(mitochondrion morphogenesis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071464"(cellular response to hydrostatic pressure)|go:"GO:0071498"(cellular response to fluid shear stress)|go:"GO:0120193"(tight junction organization)|go:"GO:2000689"(actomyosin contractile ring assembly actin filament organization)|go:"GO:2000983"(regulation of ATP citrate synthase activity)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR005326(Plectin/S10, N-terminal)|go:"GO:0048741"(skeletal muscle fiber development)|go:"GO:0005741"(mitochondrial outer membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006997"(nucleus organization)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0010467"(gene expression)|go:"GO:0010761"(fibroblast migration)|go:"GO:0010818"(T cell chemotaxis)|go:"GO:0014866"(skeletal myofibril assembly)|go:"GO:0016020"(membrane)|go:"GO:0016528"(sarcoplasm)|go:"GO:0016569"(obsolete covalent chromatin modification)|go:"GO:0019226"(transmission of nerve impulse)|interpro:IPR030269|interpro:IPR035915|interpro:IPR018159|interpro:IPR036388|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|mint:Q15149|rcsb pdb:1MB8|rcsb pdb:2N03|rcsb pdb:2ODU|rcsb pdb:2ODV|rcsb pdb:3F7P|rcsb pdb:3PDY|rcsb pdb:3PE0|rcsb pdb:4GDO|rcsb pdb:4Q58|rcsb pdb:4Q59|rcsb pdb:5J1F|rcsb pdb:5J1G|rcsb pdb:5J1H|rcsb pdb:5J1I|reactome:R-HSA-2022090|reactome:R-HSA-264870|reactome:R-HSA-446107|ensembl:ENST00000436759|ensembl:ENSP00000388180|ensembl:ENST00000527096|ensembl:ENSP00000434583|ensembl:ENSP00000323856|ensembl:ENST00000345136|ensembl:ENSP00000344848|ensembl:ENST00000354589|ensembl:ENSP00000346602|ensembl:ENST00000354958|ensembl:ENSP00000347044|ensembl:ENST00000356346|ensembl:ENSP00000348702|ensembl:ENST00000357649|ensembl:ENSP00000350277|ensembl:ENST00000398774|ensembl:ENSP00000381756|refseq:NP_000436.2|refseq:NP_958780.1|refseq:NP_958781.1|refseq:NP_958782.1|refseq:NP_958783.1|refseq:NP_958784.1|refseq:NP_958785.1|refseq:NP_958786.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95817 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-747185|uniprotkb:Q3B763|uniprotkb:Q9NT20|uniprotkb:Q9P120|uniprotkb:A8K5L8|ensembl:ENSP00000358081 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:bag3_human(display_long)|uniprotkb:Bcl-2-associated athanogene 3(gene name synonym)|uniprotkb:Bcl-2-binding protein Bis(gene name synonym)|uniprotkb:Docking protein CAIR-1(gene name synonym)|uniprotkb:BAG3(gene name)|psi-mi:BAG3(display_short)|uniprotkb:BIS(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004272.2|ensembl:ENSG00000151929(gene)|ensembl:ENST00000369085(transcript)|go:"GO:0000045"(autophagosome assembly)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006457"(protein folding)|go:"GO:0007420"(brain development)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010664"(negative regulation of striated muscle cell apoptotic process)|go:"GO:0016020"(membrane)|go:"GO:0016235"(aggresome)|go:"GO:0021510"(spinal cord development)|go:"GO:0030018"(Z disc)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0034605"(cellular response to heat)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0043005"(neuron projection)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0050821"(protein stabilization)|go:"GO:0051087"(chaperone binding)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0070842"(aggresome assembly)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0097192"(extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098840"(protein transport along microtubule)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:1903215"(negative regulation of protein targeting to mitochondrion)|go:"GO:1905337"(positive regulation of aggrephagy)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR003103(Apoptosis regulator Bcl-2 protein, BAG)|interpro:IPR036020|interpro:IPR036533|interpro:IPR039773|mint:O95817|reactome:R-HSA-3371453|go:"GO:0101031"(chaperone complex)|dip:DIP-41273N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ld26VRSMJghXG/U98A76RijSDBc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15162 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-740019|ensembl:ENSP00000345494|uniprotkb:B2R8H8|uniprotkb:B4DTE8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pls1_human(display_long)|uniprotkb:PLSCR1(gene name)|psi-mi:PLSCR1(display_short)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 1"(gene name synonym)|uniprotkb:Erythrocyte phospholipid scramblase(gene name synonym)|uniprotkb:MmTRA1b(gene name synonym)|uniprotkb:"Mg(2+)-dependent nuclease"(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000188313(gene)|ensembl:ENST00000342435(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001228"(DNA-binding transcription activator activity, RNA polymerase II-specific)|go:"GO:0001618"(virus receptor activity)|go:"GO:0003677"(DNA binding)|go:"GO:0004518"(nuclease activity)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006659"(phosphatidylserine biosynthetic process)|go:"GO:0006915"(apoptotic process)|go:"GO:0006953"(acute-phase response)|go:"GO:0008270"(zinc ion binding)|go:"GO:0010288"(response to lead ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|ensembl:ENSP00000345494|ensembl:ENST00000448787|ensembl:ENSP00000411675|refseq:NP_066928.1|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030168"(platelet activation)|go:"GO:0032791"(lead ion binding)|go:"GO:0033003"(regulation of mast cell activation)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0042609"(CD4 receptor binding)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045089"(positive regulation of innate immune response)|go:"GO:0045121"(membrane raft)|go:"GO:0045340"(mercury ion binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0051607"(defense response to virus)|go:"GO:0060368"(regulation of Fc receptor mediated stimulatory signaling pathway)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070782"(phosphatidylserine exposure on apoptotic cell surface)|go:"GO:1905820"(positive regulation of chromosome separation)|go:"GO:2000373"("positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity")|interpro:IPR005552(Scramblase)|mint:O15162|rcsb pdb:1Y2A|refseq:XP_011511209.1|refseq:XP_011511206.1|refseq:XP_005247595.1|refseq:XP_011511208.1|refseq:XP_016862118.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XudfvUkrZbB28t9tpFkokgnDFGc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P78310 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-747931|uniprotkb:O00694|uniprotkb:Q8WWT6|uniprotkb:Q8WWT7|uniprotkb:Q8WWT8|uniprotkb:Q9UKV4|ensembl:ENSP00000284878|uniprotkb:B2R8V8|uniprotkb:B7WPI3|uniprotkb:D3YHP0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cxar_human(display_long)|uniprotkb:Coxsackievirus B-adenovirus receptor(gene name synonym)|uniprotkb:HCVADR(gene name synonym)|uniprotkb:CVB3-binding protein(gene name synonym)|uniprotkb:CXADR(gene name)|psi-mi:CXADR(display_short)|uniprotkb:CAR(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001329.1|refseq:NP_001193992.1|refseq:NP_001193993.1|refseq:NP_001193994.1|go:"GO:0045121"(membrane raft)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0046629"(gamma-delta T cell activation)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0055013"(cardiac muscle cell development)|go:"GO:0070633"(transepithelial transport)|ensembl:ENSG00000154639(gene)|go:"GO:0071253"(connexin binding)|ensembl:ENST00000284878(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007005"(mitochondrion organization)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007507"(heart development)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008354"(germ cell migration)|go:"GO:0010669"(epithelial structure maintenance)|go:"GO:0014704"(intercalated disc)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030426"(growth cone)|go:"GO:0030593"(neutrophil chemotaxis)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0042802"(identical protein binding)|go:"GO:0043005"(neuron projection)|go:"GO:0044297"(cell body)|refseq:XP_011527781.1|refseq:NP_001193995.1|go:"GO:0086067"(AV node cell to bundle of His cell communication)|go:"GO:0086072"(AV node cell-bundle of His cell adhesion involved in cell communication)|go:"GO:0086082"(cell adhesive protein binding involved in AV node cell-bundle of His cell communication)|go:"GO:0098904"(regulation of AV node cell action potential)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013151(Immunoglobulin)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|rcsb pdb:1EAJ|rcsb pdb:1F5W|rcsb pdb:1JEW|rcsb pdb:1KAC|rcsb pdb:1P69|rcsb pdb:1P6A|rcsb pdb:1RSF|rcsb pdb:2J12|rcsb pdb:2J1K|rcsb pdb:2NPL|rcsb pdb:2W9L|rcsb pdb:2WBW|rcsb pdb:3J6L|rcsb pdb:3J6M|rcsb pdb:3J6N|rcsb pdb:3J6O|rcsb pdb:7DPZ|rcsb pdb:7DQ1|reactome:R-HSA-198933|reactome:R-HSA-202733 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:rISYMOJkhS94FeOElTtG8w5p4hI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TEW0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-81968|uniprotkb:Q5T2U1|uniprotkb:Q5VWV0|uniprotkb:Q5VWV4|uniprotkb:Q5VWV5|uniprotkb:Q8TEW1|uniprotkb:Q8TEW2|uniprotkb:Q8TEW3|uniprotkb:Q96K28|uniprotkb:Q96RM6|uniprotkb:Q96RM7|uniprotkb:Q9BY57|uniprotkb:Q9BY58|uniprotkb:Q9HC48|uniprotkb:Q9NWL4|uniprotkb:Q9NYE6|uniprotkb:Q5VWV3|uniprotkb:Q5VUA2|uniprotkb:Q5VUA3|uniprotkb:Q5VWV1|intact:EBI-1221123|uniprotkb:Q8TCZ9|ensembl:ENSP00000363921|intact:EBI-10975849|uniprotkb:F5H5T0|uniprotkb:Q6IQ47 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pard3_human(display_long)|uniprotkb:PARD3(gene name)|psi-mi:PARD3(display_short)|uniprotkb:PAR3(gene name synonym)|uniprotkb:PAR3A(gene name synonym)|uniprotkb:Atypical PKC isotype-specific-interacting protein(gene name synonym)|uniprotkb:CTCL tumor antigen se2-5(gene name synonym)|uniprotkb:PAR3-alpha(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021922|interpro:IPR036034|mint:Q8TEW0|rcsb pdb:2KOM|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005938"(cell cortex)|ensembl:ENSG00000148498(gene)|go:"GO:0006612"(protein targeting to membrane)|ensembl:ENST00000374789(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0007205"(protein kinase C-activating G protein-coupled receptor signaling pathway)|go:"GO:0007409"(axonogenesis)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0008104"(protein localization)|go:"GO:0008356"(asymmetric cell division)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022011"(myelination in peripheral nervous system)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0031643"(positive regulation of myelination)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033269"(internode region of axon)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043296"(apical junction complex)|go:"GO:0044295"(axonal growth cone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0060341"(regulation of cellular localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090162"(establishment of epithelial cell polarity)|refseq:NP_001171714.1|refseq:NP_001171716.1|refseq:NP_001171717.1|refseq:NP_001171718.1|refseq:NP_001171719.1|refseq:NP_001171720.1|refseq:NP_001171721.1|refseq:NP_001171722.1|refseq:NP_001171723.1|refseq:NP_062565.2|refseq:NP_001171715.1|dip:DIP-31315N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:FdOAcXyXE7jKSBJdlPcabwbnq5k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P52907 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-355586|uniprotkb:Q53FQ6|uniprotkb:Q6FHD5|ensembl:ENSP00000263168 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:caza1_human(display_long)|uniprotkb:CAPZA1(gene name)|psi-mi:CAPZA1(display_short)|uniprotkb:CapZ alpha-1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006126.1|ensembl:ENSG00000116489(gene)|ensembl:ENST00000263168(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0034329"(cell junction assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071203"(WASH complex)|interpro:IPR002189(F-actin capping protein, alpha subunit)|interpro:IPR017865|interpro:IPR037282|interpro:IPR042276|interpro:IPR042489|mint:P52907|rcsb pdb:1MQ1|rcsb pdb:1MWN|reactome:R-HSA-2132295|reactome:R-HSA-3371497|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-879415|reactome:R-HSA-8950505|reactome:R-HSA-9662360|reactome:R-HSA-983231 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:97S4WPtjgt4MDLoptRhQ2yH8UNE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q00587 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-744130|uniprotkb:Q96GN1|uniprotkb:A8K825|ensembl:ENSP00000249014 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:borg5_human(display_long)|uniprotkb:Binder of Rho GTPases 5(gene name synonym)|uniprotkb:Serum protein MSE55(gene name synonym)|uniprotkb:CEP1(gene name synonym)|uniprotkb:MSE55(gene name synonym)|uniprotkb:CDC42EP1(gene name)|psi-mi:CDC42EP1(display_short)|uniprotkb:BORG5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_689449.1|refseq:XP_006724170.1|refseq:XP_006724171.1|refseq:XP_006724172.1|ensembl:ENSG00000128283(gene)|ensembl:ENST00000249014(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0012505"(endomembrane system)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031274"(positive regulation of pseudopodium assembly)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR029273|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|refseq:XP_016884030.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ros/Dvfb6rdmhUyT755WtSswQjQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UHN6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2876905|uniprotkb:B2RTQ6|uniprotkb:Q8NBP6|uniprotkb:Q5T841|uniprotkb:Q5T840|uniprotkb:Q9P2D5|uniprotkb:Q5T839|uniprotkb:Q5T838|uniprotkb:A6H8W9|ensembl:ENSP00000366243 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ceip2_human(display_long)|uniprotkb:CEMIP2(gene name)|psi-mi:CEMIP2(display_short)|uniprotkb:KIAA1412(gene name synonym)|uniprotkb:TMEM2(gene name synonym)|uniprotkb:Transmembrane protein 2(gene name synonym)|uniprotkb:Cell migration-inducing hyaluronidase 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001129292.1|refseq:NP_037522.1|refseq:XP_005251926.1|ensembl:ENSG00000135048(gene)|ensembl:ENST00000377044(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0004415"(hyalurononglucosaminidase activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030214"(hyaluronan catabolic process)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903670"(regulation of sprouting angiogenesis)|interpro:IPR011050(Pectin lyase fold/virulence factor)|interpro:IPR019316|interpro:IPR039473|interpro:IPR039477|mint:Q9UHN6 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:LVdpEH7Df1biSXHseli56Y9l9XQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WVV4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2877727|ensembl:ENSP00000262753|uniprotkb:Q9H738|uniprotkb:Q9H744|uniprotkb:Q5H9F0|uniprotkb:Q8NG12|uniprotkb:Q5H9E9|uniprotkb:Q9H5Y2|uniprotkb:A8K2U5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pof1b_human(display_long)|uniprotkb:POF1B(gene name)|psi-mi:POF1B(display_short)|uniprotkb:Premature ovarian failure protein 1B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000262753(transcript)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005884"(actin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030057"(desmosome)|go:"GO:0051015"(actin filament binding)|go:"GO:0070830"(bicellular tight junction assembly)|interpro:IPR026186|mint:Q8WVV4|rcsb pdb:3BH9|ensembl:ENSG00000124429(gene)|refseq:NP_001294869.1|refseq:NP_079197.3|ensembl:ENSP00000262753|ensembl:ENST00000373145|ensembl:ENSP00000362238 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:rigOH+ulgEPejDWfjfmcn2M2B2M9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P53990 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-945994|intact:EBI-4324656|uniprotkb:A8KAH5|uniprotkb:Q9BQ81|uniprotkb:Q9BWN2|uniprotkb:Q3SYM4|uniprotkb:J3QLU7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ist1_human(display_long)|uniprotkb:IST1(gene name)|psi-mi:IST1(display_short)|uniprotkb:Putative MAPK-activating protein PM28(gene name synonym)|uniprotkb:KIAA0174(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055576.2|refseq:NP_001257904.1|refseq:NP_001257906.1|refseq:NP_001257905.1|refseq:NP_001257907.1|mint:P53990|dip:DIP-42546N|go:"GO:0005576"(extracellular region)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0008104"(protein localization)|go:"GO:0009838"(abscission)|go:"GO:0015031"(protein transport)|go:"GO:0019076"(viral release from host cell)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030496"(midbody)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045862"(positive regulation of proteolysis)|go:"GO:0046745"(viral capsid secondary envelopment)|go:"GO:0048672"(positive regulation of collateral sprouting)|go:"GO:0051301"(cell division)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090541"(MIT domain binding)|go:"GO:0090543"(Flemming body)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005061(Protein of unknown function DUF292, eukaryotic)|interpro:IPR042277|rcsb pdb:3FRR|rcsb pdb:3FRS|rcsb pdb:3JC1|rcsb pdb:4U7E|rcsb pdb:4U7I|rcsb pdb:4U7Y|rcsb pdb:4WZX|rcsb pdb:6E8G|rcsb pdb:6TZ4|rcsb pdb:6TZ5|rcsb pdb:6TZA|reactome:R-HSA-6798695|reactome:R-HSA-9668328 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RbWwKZ+sftO2x3UkFz8zAxVi2CU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96QZ7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-924464|uniprotkb:O00309|uniprotkb:O43863|uniprotkb:O75085|uniprotkb:Q96QZ8|uniprotkb:Q96QZ9|intact:EBI-1059162|uniprotkb:A8K188 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:magi1_human(display_long)|uniprotkb:MAGI1(gene name)|psi-mi:MAGI1(display_short)|uniprotkb:BAIAP1(gene name synonym)|uniprotkb:BAP1(gene name synonym)|uniprotkb:TNRC19(gene name synonym)|uniprotkb:BAI1-associated protein 1(gene name synonym)|uniprotkb:Membrane-associated guanylate kinase inverted 1(gene name synonym)|uniprotkb:Atrophin-1-interacting protein 3(gene name synonym)|uniprotkb:WW domain-containing protein 3(gene name synonym)|uniprotkb:Trinucleotide repeat-containing gene 19 protein(gene name synonym)|uniprotkb:AIP3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001028229.1|refseq:NP_004733.2|refseq:NP_056335.1|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR020590|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR030033|interpro:IPR027417|refseq:XP_005265621.1|mint:Q96QZ7|interpro:IPR036020|interpro:IPR036034|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0022409"(positive regulation of cell-cell adhesion)|go:"GO:0030054"(cell junction)|go:"GO:0042995"(cell projection)|go:"GO:0051393"(alpha-actinin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071944"(cell periphery)|rcsb pdb:1WBP|rcsb pdb:2KPK|rcsb pdb:2KPL|rcsb pdb:2Q9V|rcsb pdb:2R4H|rcsb pdb:2YSD|rcsb pdb:2YSE|rcsb pdb:2ZAJ|rcsb pdb:3BPU|rcsb pdb:5N7D|rcsb pdb:5N7F|rcsb pdb:5N7G|rcsb pdb:6TWU|rcsb pdb:6TWX|rcsb pdb:6TWY - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WN0iaCIXUObtJMGO7eRlQdaGDSk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6P9H4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10253274|uniprotkb:Q96N65|uniprotkb:Q5SGD5|uniprotkb:C9IZX4|ensembl:ENSP00000475915 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cnkr3_human(display_long)|uniprotkb:CNKSR3(gene name)|psi-mi:CNKSR3(display_short)|uniprotkb:CNK homolog protein 3(gene name synonym)|uniprotkb:CNKSR family member 3(gene name synonym)|uniprotkb:MAGI1(gene name synonym)|uniprotkb:Maguin-like protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_775786.2|ensembl:ENSG00000153721(gene)|ensembl:ENST00000607772(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR010599(Connector enhancer of kinase suppressor of ras 2)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR017874|interpro:IPR036034 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XblyCRyMkFkCnL104LVme415sSc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H2H9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-9978441|ensembl:ENSP00000381634|ensembl:ENSP00000398142|ensembl:ENSP00000447853|ensembl:ENSP00000449607|uniprotkb:Q8NC61|uniprotkb:Q8NCF8|uniprotkb:Q96JX2|uniprotkb:Q9H2Q2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:s38a1_human(display_long)|uniprotkb:SLC38A1(gene name)|psi-mi:SLC38A1(display_short)|uniprotkb:ATA1(gene name synonym)|uniprotkb:NAT2(gene name synonym)|uniprotkb:SAT1(gene name synonym)|uniprotkb:SNAT1(gene name synonym)|uniprotkb:Amino acid transporter A1(gene name synonym)|uniprotkb:N-system amino acid transporter 2(gene name synonym)|uniprotkb:Solute carrier family 38 member 1(gene name synonym)|uniprotkb:System A amino acid transporter 1(gene name synonym)|uniprotkb:System N amino acid transporter 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000111371(gene)|ensembl:ENST00000398637(transcript)|ensembl:ENST00000439706(transcript)|ensembl:ENST00000546893(transcript)|ensembl:ENST00000549049(transcript)|go:"GO:0001504"(neurotransmitter uptake)|go:"GO:0003333"(amino acid transmembrane transport)|go:"GO:0005283"("amino acid:sodium symporter activity")|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0007565"(female pregnancy)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015179"(L-amino acid transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0005295"("neutral amino acid:sodium symporter activity")|go:"GO:0030424"(axon)|go:"GO:0043025"(neuronal cell body)|go:"GO:0070062"(extracellular exosome)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1902475"(L-alpha-amino acid transmembrane transport)|interpro:IPR013057(Amino acid transporter, transmembrane)|reactome:R-HSA-210455|reactome:R-HSA-352230|go:"GO:0098591"(external side of apical plasma membrane)|refseq:NP_001070952.1|refseq:NP_001265316.1|refseq:NP_001265317.1|refseq:NP_001265318.1|refseq:NP_109599.3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:bywv401DbQBHRZvcPc8o8mp8nfE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UBC9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-355179|uniprotkb:A5YKK8|uniprotkb:B2R4G8|uniprotkb:O75597|uniprotkb:Q4ZGI7|uniprotkb:Q5T525|uniprotkb:Q8NET7|uniprotkb:Q9UDG3|uniprotkb:D3DV32|ensembl:ENSP00000295367|ensembl:ENSP00000330391 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sprr3_human(display_long)|uniprotkb:SPRR3(gene name)|psi-mi:SPRR3(display_short)|uniprotkb:SPRC(gene name synonym)|uniprotkb:Cornifin beta(gene name synonym)|uniprotkb:Esophagin(gene name synonym)|uniprotkb:22 kDa pancornulin(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001091058.1|refseq:NP_005407.1|ensembl:ENST00000295367(transcript)|ensembl:ENST00000331860(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003302("Cornifin (SPRR)")|reactome:R-HSA-6809371|ensembl:ENSG00000163209(gene) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GZ2WJ8NNau2HRIopItKnuR8fvYw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35579 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350338|uniprotkb:O60805|ensembl:ENSP00000216181|uniprotkb:Q86T83|intact:EBI-1054343|uniprotkb:A8K6E4|uniprotkb:Q60FE2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:myh9_human(display_long)|uniprotkb:MYH9(gene name)|psi-mi:MYH9(display_short)|uniprotkb:Myosin heavy chain 9(gene name synonym)|uniprotkb:Myosin heavy chain, non-muscle IIa(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain IIa(gene name synonym)|uniprotkb:Cellular myosin heavy chain, type A(gene name synonym)|uniprotkb:Non-muscle myosin heavy chain A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002464.1|ensembl:ENSG00000100345(gene)|ensembl:ENST00000216181(transcript)|go:"GO:0000146"(microfilament motor activity)|go:"GO:0000212"(meiotic spindle organization)|go:"GO:0001525"(angiogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001931"(uropod)|go:"GO:0003723"(RNA binding)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005826"(actomyosin contractile ring)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006509"(membrane protein ectodomain proteolysis)|go:"GO:0006911"(phagocytosis, engulfment)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007520"(myoblast fusion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0015031"(protein transport)|refseq:XP_011528499.1|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016460"(myosin II complex)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030220"(platelet formation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032418"(lysosome localization)|go:"GO:0032506"(cytokinetic process)|go:"GO:0032796"(uropod organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042641"(actomyosin)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043531"(ADP binding)|go:"GO:0043534"(blood vessel endothelial cell migration)|go:"GO:0045055"(regulated exocytosis)|go:"GO:0045296"(cadherin binding)|go:"GO:0050900"(leukocyte migration)|go:"GO:0051015"(actin filament binding)|go:"GO:0051295"(establishment of meiotic spindle localization)|go:"GO:0060471"(cortical granule exocytosis)|go:"GO:0060473"(cortical granule)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0097513"(myosin II filament)|go:"GO:1903919"(negative regulation of actin filament severing)|rcsb pdb:4CFR|rcsb pdb:4ETO|reactome:R-HSA-1445148|reactome:R-HSA-2029482|reactome:R-HSA-3928663|reactome:R-HSA-416572|reactome:R-HSA-5625740|reactome:R-HSA-5625900|reactome:R-HSA-5627117|reactome:R-HSA-5627123|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9662834|reactome:R-HSA-9664422|go:"GO:1903923"(positive regulation of protein processing in phagocytic vesicle)|go:"GO:1905684"(regulation of plasma membrane repair)|interpro:IPR000048(IQ calmodulin-binding region)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR002928(Myosin tail)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR036305|interpro:IPR036961|mint:P35579|rcsb pdb:2LNK|rcsb pdb:3ZWH|rcsb pdb:4CFQ|refseq:XP_016884292.1|refseq:XP_016884293.1|refseq:XP_016884294.1|refseq:XP_016884295.1|dip:DIP-33103N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fSOtpFpr8PSnAG5UdAr/khwkzJs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9P227 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-20721052|ensembl:ENSP00000479208|ensembl:ENSP00000481862 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rhg23_human(display_long)|uniprotkb:Rho-type GTPase-activating protein 23(gene name synonym)|uniprotkb:ARHGAP23(gene name)|psi-mi:ARHGAP23(display_short)|uniprotkb:KIAA1501(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000273780(gene)|ensembl:ENSG00000275832(gene)|ensembl:ENST00000610551(transcript)|ensembl:ENST00000622683(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|interpro:IPR041681|reactome:R-HSA-8980692|reactome:R-HSA-9013149|refseq:NP_001186346.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:mMI74CkN/udBFOL6NiHL+tpBJ009606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P16333 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-389883|uniprotkb:B7Z751|ensembl:ENSP00000288986|ensembl:ENSP00000417273|intact:EBI-3448658|uniprotkb:D3DNE3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nck1_human(display_long)|uniprotkb:NCK1(gene name)|psi-mi:NCK1(display_short)|uniprotkb:NCK(gene name synonym)|uniprotkb:NCK adaptor protein 1(gene name synonym)|uniprotkb:SH2/SH3 adaptor protein NCK-alpha(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001278928.1|ensembl:ENSG00000158092(gene)|ensembl:ENST00000288986(transcript)|ensembl:ENST00000481752(transcript)|go:"GO:0000164"(protein phosphatase type 1 complex)|go:"GO:0004860"(protein kinase inhibitor activity)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007172"(signal complex assembly)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0012506"(vesicle membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030159"(signaling receptor complex adaptor activity)|refseq:NP_001177725.1|refseq:NP_006144.1|go:"GO:1903676"(positive regulation of cap-dependent translational initiation)|go:"GO:1903679"(positive regulation of cap-independent translational initiation)|go:"GO:1903898"(negative regulation of PERK-mediated unfolded protein response)|go:"GO:1903912"(negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:1990441"(negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR017304(Cytoplasmic, NCK)|interpro:IPR028526|interpro:IPR035562|interpro:IPR035564|interpro:IPR035565|interpro:IPR035882|interpro:IPR036028|interpro:IPR036860|mint:P16333|rcsb pdb:2CI8|rcsb pdb:2CI9|rcsb pdb:2CUB|rcsb pdb:2JS0|rcsb pdb:2JS2|rcsb pdb:2JW4|rcsb pdb:5QU1|rcsb pdb:5QU2|rcsb pdb:5QU3|rcsb pdb:5QU4|rcsb pdb:5QU5|rcsb pdb:5QU6|rcsb pdb:5QU7|rcsb pdb:5QU8|rcsb pdb:5QUA|reactome:R-HSA-186763|reactome:R-HSA-202433|reactome:R-HSA-2029482|reactome:R-HSA-373753|reactome:R-HSA-418885|reactome:R-HSA-428540|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9664422|reactome:R-HSA-983695|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0033137"(negative regulation of peptidyl-serine phosphorylation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042110"(T cell activation)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046627"(negative regulation of insulin receptor signaling pathway)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0051707"(response to other organism)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070262"(peptidyl-serine dephosphorylation)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:1902237"(positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|dip:DIP-639N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:UzgLYRQQ9VjN7eKkgn76At/7cSA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NDI1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2689720|uniprotkb:Q9NWI9|uniprotkb:Q6QNV2|uniprotkb:Q6NX72|uniprotkb:Q53TV6|uniprotkb:Q6PIT3|uniprotkb:Q53TG7|uniprotkb:Q580X2|uniprotkb:O94977|ensembl:ENSP00000263991 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ehbp1_human(display_long)|uniprotkb:KIAA0903(gene name synonym)|uniprotkb:NACSIN(gene name synonym)|uniprotkb:EHBP1(gene name)|psi-mi:EHBP1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000263991|ensembl:ENST00000405015|ensembl:ENSP00000384143|ensembl:ENST00000405289|ensembl:ENSP00000385524|ensembl:ENST00000431489|ensembl:ENSP00000403783|refseq:XP_011531015.1|refseq:XP_011531016.1|refseq:XP_011531017.1|refseq:NP_001136086.1|refseq:NP_001136087.1|refseq:NP_001136088.1|refseq:NP_056067.2|refseq:XP_016859136.1|refseq:XP_016859137.1|refseq:XP_016859138.1|refseq:XP_005264282.1|refseq:XP_005264283.1|refseq:XP_005264284.1|refseq:XP_016859132.1|refseq:XP_016859133.1|refseq:XP_016859140.1|rcsb pdb:6ZSI|rcsb pdb:6ZSJ|rcsb pdb:2D89|rcsb pdb:6ZSH|ensembl:ENSG00000115504(gene)|ensembl:ENST00000263991(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR019448|interpro:IPR022735|interpro:IPR029944|interpro:IPR036872 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:sDcegXBYi8eQp7KReaysxBy3Ogc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P11142 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351896|uniprotkb:Q9H3R6|ensembl:ENSP00000227378|ensembl:ENSP00000432083|ensembl:ENSP00000437125 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:hsp7c_human(display_long)|uniprotkb:HSPA8(gene name)|psi-mi:HSPA8(display_short)|uniprotkb:HSC70(gene name synonym)|uniprotkb:HSP73(gene name synonym)|uniprotkb:HSPA10(gene name synonym)|uniprotkb:Heat shock 70 kDa protein 8(gene name synonym)|uniprotkb:Lipopolysaccharide-associated protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006588.1|refseq:NP_694881.1|refseq:XP_011541100.1|ensembl:ENSG00000109971(gene)|ensembl:ENST00000227378(transcript)|ensembl:ENST00000532636(transcript)|ensembl:ENST00000534624(transcript)|go:"GO:0000974"(Prp19 complex)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005770"(late endosome)|go:"GO:0005776"(autophagosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006397"(mRNA processing)|go:"GO:0006457"(protein folding)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008380"(RNA splicing)|go:"GO:0009267"(cellular response to starvation)|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016887"(ATP hydrolysis activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030425"(dendrite)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042026"(protein refolding)|go:"GO:0042470"(melanosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0043195"(terminal bouton)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0046034"(ATP metabolic process)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051787"(misfolded protein binding)|go:"GO:0055131"(C3HC4-type RING finger domain binding)|go:"GO:0061024"(membrane organization)|go:"GO:0061202"(clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane)|go:"GO:0061635"(regulation of protein complex stability)|go:"GO:0061684"(chaperone-mediated autophagy)|go:"GO:0061738"(late endosomal microautophagy)|go:"GO:0061740"(protein targeting to lysosome involved in chaperone-mediated autophagy)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072562"(blood microparticle)|go:"GO:0098575"(lumenal side of lysosomal membrane)|go:"GO:0098684"(photoreceptor ribbon synapse)|go:"GO:0098690"(glycinergic synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099634"(postsynaptic specialization membrane)|go:"GO:0101031"(chaperone complex)|go:"GO:0140545"(protein disaggregase activity)|go:"GO:0140597"(protein carrier chaperone)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902904"(negative regulation of supramolecular fiber organization)|go:"GO:1904589"(regulation of protein import)|go:"GO:1904764"(chaperone-mediated autophagy translocation complex disassembly)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990832"(slow axonal transport)|go:"GO:1990833"(clathrin-uncoating ATPase activity)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR013126(Heat shock protein 70)|interpro:IPR018181|interpro:IPR029047|interpro:IPR029048|interpro:IPR043129|mint:P11142|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:3ESK|rcsb pdb:3FZF|rcsb pdb:3FZH|rcsb pdb:3FZK|rcsb pdb:3FZL|rcsb pdb:3FZM|rcsb pdb:3LDQ|rcsb pdb:3M3Z|rcsb pdb:4H5N|rcsb pdb:4H5R|rcsb pdb:4H5T|rcsb pdb:4H5V|rcsb pdb:4H5W|rcsb pdb:4HWI|rcsb pdb:4KBQ|rcsb pdb:5AQF|rcsb pdb:5AQG|rcsb pdb:5AQH|rcsb pdb:5AQI|rcsb pdb:5AQJ|rcsb pdb:5AQK|rcsb pdb:5AQL|rcsb pdb:5AQM|rcsb pdb:5AQN|rcsb pdb:5AQO|rcsb pdb:5AQP|rcsb pdb:5AQQ|rcsb pdb:5AQR|rcsb pdb:5AQS|rcsb pdb:5AQT|rcsb pdb:5AQU|rcsb pdb:5AQV|rcsb pdb:6B1I|rcsb pdb:6B1M|rcsb pdb:6B1N|rcsb pdb:6ZYJ|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-447041|reactome:R-HSA-450408|reactome:R-HSA-6785807|reactome:R-HSA-6798695|reactome:R-HSA-72163|reactome:R-HSA-8856828|reactome:R-HSA-8876725|reactome:R-HSA-888590|reactome:R-HSA-9613354|reactome:R-HSA-9613829|reactome:R-HSA-9615710|dip:DIP-32874N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0I+wYut3naJRzzgmMSax/1mZZwA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P63104 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-347088|ensembl:ENSP00000309503|ensembl:ENSP00000379281|ensembl:ENSP00000379283|ensembl:ENSP00000379286|ensembl:ENSP00000379287|ensembl:ENSP00000379288|ensembl:ENSP00000395114|ensembl:ENSP00000398599|uniprotkb:P29213|uniprotkb:P29312|uniprotkb:Q32P43|uniprotkb:Q5XJ08|uniprotkb:Q6GPI2|uniprotkb:Q6IN74|uniprotkb:Q6NUR9|uniprotkb:Q6P3U9|uniprotkb:Q86V33|uniprotkb:A8K1N0|uniprotkb:B7Z465 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:1433z_human(display_long)|uniprotkb:YWHAZ(gene name)|psi-mi:YWHAZ(display_short)|uniprotkb:Protein kinase C inhibitor protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000164924(gene)|ensembl:ENST00000353245(transcript)|ensembl:ENST00000395951(transcript)|ensembl:ENST00000395953(transcript)|ensembl:ENST00000395956(transcript)|ensembl:ENST00000395957(transcript)|ensembl:ENST00000395958(transcript)|ensembl:ENST00000419477(transcript)|ensembl:ENST00000457309(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003016"(respiratory system process)|go:"GO:0003723"(RNA binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006605"(protein targeting)|go:"GO:0007165"(signal transduction)|go:"GO:0008039"(synaptic target recognition)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030324"(lung development)|go:"GO:0031982"(vesicle)|go:"GO:0035148"(tube formation)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0042470"(melanosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070371"(ERK1 and ERK2 cascade)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0072562"(blood microparticle)|go:"GO:0090128"(regulation of synapse maturation)|go:"GO:0090168"(Golgi reassembly)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR000308(14-3-3 protein)|interpro:IPR023409|interpro:IPR023410|interpro:IPR036815|rcsb pdb:1IB1|rcsb pdb:1QJA|rcsb pdb:1QJB|rcsb pdb:2C1J|rcsb pdb:2C1N|rcsb pdb:2O02|rcsb pdb:2WH0|rcsb pdb:3CU8|mint:P63104|rcsb pdb:3NKX|rcsb pdb:3RDH|rcsb pdb:4BG6|rcsb pdb:4FJ3|rcsb pdb:4HKC|rcsb pdb:4IHL|rcsb pdb:4N7G|rcsb pdb:4N7Y|rcsb pdb:4N84|rcsb pdb:4WRQ|rcsb pdb:4ZDR|rcsb pdb:5D2D|rcsb pdb:5D3F|rcsb pdb:5EWZ|rcsb pdb:5EXA|rcsb pdb:5JM4|rcsb pdb:5M35|rcsb pdb:5M36|rcsb pdb:5M37|rcsb pdb:5NAS|rcsb pdb:5ULO|rcsb pdb:5WXN|rcsb pdb:5XY9|rcsb pdb:6EF5|rcsb pdb:6EJL|rcsb pdb:6EWW|rcsb pdb:6F08|rcsb pdb:6F09|rcsb pdb:6FN9|rcsb pdb:5J31|rcsb pdb:6FNA|rcsb pdb:6FNB|rcsb pdb:6FNC|rcsb pdb:6Q0K|rcsb pdb:6RLZ|rcsb pdb:6U2H|rcsb pdb:6XAG|rcsb pdb:6YMO|rcsb pdb:6YO8|rcsb pdb:6ZFD|rcsb pdb:6ZFG|rcsb pdb:7D8H|rcsb pdb:7D8P|rcsb pdb:7D9V|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-3769402|reactome:R-HSA-392517|reactome:R-HSA-430116|reactome:R-HSA-450604|reactome:R-HSA-512988|reactome:R-HSA-5625740|rcsb pdb:6YOS|reactome:R-HSA-5628897|reactome:R-HSA-75035|reactome:R-HSA-9013700|reactome:R-HSA-9604323|reactome:R-HSA-9614399|refseq:NP_001129171.1|refseq:NP_001129172.1|refseq:NP_001129173.1|refseq:NP_001129174.1|refseq:NP_003397.1|refseq:NP_663723.1|refseq:XP_005251118.1|refseq:XP_005251120.1|refseq:XP_016869299.1|refseq:XP_016869300.1|dip:DIP-563N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:70ZqFn0J1A7ykybulqWg4Ll21+U9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P61978 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-304185|intact:EBI-28971491|ensembl:ENSP00000317788|ensembl:ENSP00000353552|uniprotkb:Q07244|uniprotkb:Q15671|uniprotkb:Q59F98|uniprotkb:Q60577|uniprotkb:Q922Y7|uniprotkb:Q96J62|uniprotkb:Q5T6W4|intact:EBI-3440248|uniprotkb:Q6IBN1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:hnrpk_human(display_long)|uniprotkb:HNRNPK(gene name)|psi-mi:HNRNPK(display_short)|uniprotkb:HNRPK(gene name synonym)|uniprotkb:Transformation up-regulated nuclear protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000165119(gene)|go:"GO:0010988"(regulation of low-density lipoprotein particle clearance)|go:"GO:0016020"(membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|ensembl:ENST00000351839(transcript)|ensembl:ENST00000360384(transcript)|go:"GO:0000398"(mRNA splicing, via spliceosome)|go:"GO:0000785"(chromatin)|go:"GO:0002102"(podosome)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006396"(RNA processing)|go:"GO:0007165"(signal transduction)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048024"(regulation of mRNA splicing, via spliceosome)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0048260"(positive regulation of receptor-mediated endocytosis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071013"(catalytic step 2 spliceosome)|go:"GO:1902165"(regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator)|go:"GO:1905599"(positive regulation of low-density lipoprotein receptor activity)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR012987(ROK, N-terminal)|interpro:IPR033090|interpro:IPR036612|mint:P61978|rcsb pdb:1J5K|rcsb pdb:1KHM|rcsb pdb:1ZZI|rcsb pdb:1ZZJ|go:"GO:0043066"(negative regulation of apoptotic process)|reactome:R-HSA-4570464|reactome:R-HSA-72163|reactome:R-HSA-72203|reactome:R-HSA-9610379|rcsb pdb:1ZZK|refseq:NP_002131.2|refseq:NP_112552.1|refseq:NP_112553.1|ensembl:ENSP00000317788|ensembl:ENSP00000353552|ensembl:ENST00000376263|ensembl:ENSP00000365439|ensembl:ENST00000376281|ensembl:ENSP00000365458|refseq:NP_001305115.1|refseq:NP_001305116.1|refseq:NP_001305117.1|refseq:XP_016870157.1|refseq:XP_005252017.1|refseq:XP_005252020.1|refseq:XP_005252022.1|dip:DIP-31805N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:YZQD5JJkHPUMtZ4XUA9fQkNfXzc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O14745 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-349787|uniprotkb:O43552|uniprotkb:Q86WQ5|ensembl:ENSP00000262613|uniprotkb:B3KY21|intact:EBI-15579389 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nhrf1_human(display_long)|uniprotkb:SLC9A3R1(gene name)|psi-mi:SLC9A3R1(display_short)|uniprotkb:NHERF(gene name synonym)|uniprotkb:NHERF1(gene name synonym)|uniprotkb:Ezrin-radixin-moesin-binding phosphoprotein 50(gene name synonym)|uniprotkb:"Regulatory cofactor of Na(+)/H(+) exchanger"(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004243.1|ensembl:ENSG00000109062(gene)|ensembl:ENST00000262613(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0003096"(renal sodium ion transport)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005902"(microvillus)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007097"(nuclear migration)|go:"GO:0007191"(adenylate cyclase-activating dopamine receptor signaling pathway)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010642"(negative regulation of platelet-derived growth factor receptor signaling pathway)|go:"GO:0012505"(endomembrane system)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0015185"(gamma-aminobutyric acid transmembrane transporter activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0017081"(chloride channel regulator activity)|go:"GO:0019902"(phosphatase binding)|go:"GO:0019933"(cAMP-mediated signaling)|go:"GO:0022612"(gland morphogenesis)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030643"(cellular phosphate ion homeostasis)|go:"GO:0031526"(brush border membrane)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031698"(beta-2 adrenergic receptor binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0031982"(vesicle)|go:"GO:0032415"("regulation of sodium:proton antiporter activity")|go:"GO:0032416"("negative regulation of sodium:proton antiporter activity")|go:"GO:0032426"(stereocilium tip)|go:"GO:0032782"(bile acid secretion)|go:"GO:0034635"(glutathione transport)|go:"GO:0034767"(positive regulation of ion transmembrane transport)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0043621"(protein self-association)|go:"GO:0044062"(regulation of excretion)|go:"GO:0044782"(cilium organization)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045159"(myosin II binding)|go:"GO:0045198"(establishment of epithelial cell apical/basal polarity)|go:"GO:0045199"(maintenance of epithelial cell apical/basal polarity)|go:"GO:0045859"(regulation of protein kinase activity)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050780"(dopamine receptor binding)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051939"(gamma-aminobutyric acid import)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060158"(phospholipase C-activating dopamine receptor signaling pathway)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070293"(renal absorption)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070851"(growth factor receptor binding)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090660"(cerebrospinal fluid circulation)|go:"GO:0097225"(sperm midpiece)|go:"GO:0097291"(renal phosphate ion absorption)|go:"GO:0098739"(import across plasma membrane)|go:"GO:0098797"(plasma membrane protein complex)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:2001244"(positive regulation of intrinsic apoptotic signaling pathway)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031199|interpro:IPR036034|interpro:IPR041489|mint:O14745|rcsb pdb:1G9O|rcsb pdb:1GQ4|rcsb pdb:1GQ5|rcsb pdb:1I92|rcsb pdb:1SGH|rcsb pdb:2D10|rcsb pdb:2JXO|rcsb pdb:2KJD|rcsb pdb:2KRG|rcsb pdb:2M0T|rcsb pdb:2M0U|rcsb pdb:2M0V|rcsb pdb:2OZF|rcsb pdb:4JL7|rcsb pdb:4LMM|rcsb pdb:4N6X|rcsb pdb:4PQW|rcsb pdb:4Q3H|rcsb pdb:6RQR|rcsb pdb:4MPA|dip:DIP-29092N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:03E30U6coFBcC3BeKOYnInfG/BI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H444 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-749627|uniprotkb:Q53ZD6|uniprotkb:E1P5N4|ensembl:ENSP00000217402 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:chm4b_human(display_long)|uniprotkb:Chromatin-modifying protein 4b(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 32-2(gene name synonym)|uniprotkb:SNF7-2(gene name synonym)|uniprotkb:SNF7 homolog associated with Alix 1(gene name synonym)|uniprotkb:CHMP4B(gene name)|psi-mi:CHMP4B(display_short)|uniprotkb:C20orf178(gene name synonym)|uniprotkb:SHAX1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_789782.1|dip:DIP-29924N|ensembl:ENSG00000101421(gene)|ensembl:ENST00000217402(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006620"(posttranslational protein targeting to endoplasmic reticulum membrane)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010458"(exit from mitosis)|go:"GO:0016236"(macroautophagy)|go:"GO:0030117"(membrane coat)|go:"GO:0030496"(midbody)|go:"GO:0031468"(nuclear membrane reassembly)|go:"GO:0031902"(late endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0036438"(maintenance of lens transparency)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0046761"(viral budding from plasma membrane)|go:"GO:0051258"(protein polymerization)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090148"(membrane fission)|go:"GO:0090611"(ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902902"(negative regulation of autophagosome assembly)|interpro:IPR005024(Snf7)|mint:Q9H444|rcsb pdb:3C3Q|rcsb pdb:3UM3|rcsb pdb:4ABM|rcsb pdb:5MK2|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:hbJvirD5+L7fxzOoWbiP1ky6c9M9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60645 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1052278|uniprotkb:Q8TEN6|uniprotkb:Q8WUW0|uniprotkb:Q96DI4|uniprotkb:Q6P2E8|ensembl:ENSP00000323377|ensembl:ENSP00000425587|intact:EBI-11944037 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:exoc3_human(display_long)|uniprotkb:Exocyst complex component Sec6(gene name synonym)|uniprotkb:EXOC3(gene name)|psi-mi:EXOC3(display_short)|uniprotkb:SEC6(gene name synonym)|uniprotkb:SEC6L1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_016864492.1|refseq:XP_016864493.1|ensembl:ENSG00000180104(gene)|ensembl:ENST00000315013(transcript)|ensembl:ENST00000512944(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0000149"(SNARE binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006887"(exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0030496"(midbody)|go:"GO:0030667"(secretory granule membrane)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051601"(exocyst localization)|interpro:IPR010326(Exocyst complex component Sec6)|interpro:IPR042532|reactome:R-HSA-1445148|reactome:R-HSA-264876|reactome:R-HSA-5620916|go:"GO:0030426"(growth cone)|refseq:NP_009208.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7nhIGGYkkrej3iW0UKDqP5BwUz09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13625 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-77642|uniprotkb:Q12892|uniprotkb:Q86X75|uniprotkb:Q96KQ3|uniprotkb:B4DG66 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:aspp2_human(display_long)|uniprotkb:TP53BP2(gene name)|psi-mi:TP53BP2(display_short)|uniprotkb:ASPP2(gene name synonym)|uniprotkb:BBP(gene name synonym)|uniprotkb:Tumor suppressor p53-binding protein 2(gene name synonym)|uniprotkb:Bcl2-binding protein(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-51(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001026855.2|refseq:NP_005417.1|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030054"(cell junction)|go:"GO:0042802"(identical protein binding)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051059"(NF-kappaB binding)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1900119"(positive regulation of execution phase of apoptosis)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|rcsb pdb:1YCS|rcsb pdb:2UWQ|rcsb pdb:4A63|rcsb pdb:4IRV|rcsb pdb:6GHM|rcsb pdb:6HKP|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|ensembl:ENST00000343537|ensembl:ENSP00000341957|ensembl:ENSG00000143514|ensembl:ENST00000391878|ensembl:ENSP00000375750|refseq:XP_011542571.1|dip:DIP-426N|mint:Q13625 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:p3shTkfKZ6Ipy/xOQok7jfGD9vg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T6F2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2514383|ensembl:ENSP00000368540|ensembl:ENSP00000507293|ensembl:ENSP00000508372|uniprotkb:Q5JV03|uniprotkb:Q9P237|uniprotkb:Q8NC94|uniprotkb:Q6PK34|uniprotkb:Q2M2R4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ubap2_human(display_long)|uniprotkb:UBAP2(gene name)|psi-mi:UBAP2(display_short)|uniprotkb:KIAA1491(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001269458.1|refseq:NP_060919.3|ensembl:ENSG00000137073(gene)|ensembl:ENST00000379238(transcript)|ensembl:ENST00000682239(transcript)|ensembl:ENST00000684158(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0045296"(cadherin binding)|go:"GO:0005634"(nucleus)|interpro:IPR009060(UBA-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR022166|refseq:NP_001269459.1|ensembl:ENSP00000368540|ensembl:ENSP00000507293|ensembl:ENSP00000508372 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0bcavAC5MrP55wijYi8LYZbT6ys9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P62424 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-354172|uniprotkb:P11518|uniprotkb:Q5T8U4|ensembl:ENSP00000361076|ensembl:ENSP00000487443 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl7a_human(display_long)|uniprotkb:RPL7A(gene name)|psi-mi:RPL7A(display_short)|uniprotkb:SURF-3(gene name synonym)|uniprotkb:SURF3(gene name synonym)|uniprotkb:Surfeit locus protein 3(gene name synonym)|uniprotkb:PLA-X polypeptide(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL8(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000963.1|dip:DIP-31502N|ensembl:ENSG00000148303(gene)|ensembl:ENSG00000280858(gene)|ensembl:ENST00000323345(transcript)|ensembl:ENST00000630979(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR001921(Ribosomal protein L7A)|interpro:IPR004037(Ribosomal protein L7Ae)|interpro:IPR004038(Ribosomal protein L7Ae/L30e/S12e/Gadd45)|interpro:IPR018492|interpro:IPR029064|mint:P62424|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|go:"GO:0005634"(nucleus)|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:shPtLmc+oabT/rSwho+tP1iJy4k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NFX7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-27013124|ensembl:ENSP00000324302|ensembl:ENSP00000379928|ensembl:ENSP00000397212|ensembl:ENSP00000449379|ensembl:ENSP00000449536|uniprotkb:D3DS78|uniprotkb:Q8N3H1|uniprotkb:Q8N8D5|uniprotkb:Q96GF3|uniprotkb:Q9P008 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stxb6_human(display_long)|uniprotkb:STXBP6(gene name)|psi-mi:STXBP6(display_short)|uniprotkb:Amisyn(gene name synonym)|uniprotkb:HSPC156(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000168952(gene)|ensembl:ENST00000323944(transcript)|ensembl:ENST00000396700(transcript)|ensembl:ENST00000419632(transcript)|ensembl:ENST00000546511(transcript)|ensembl:ENST00000550887(transcript)|go:"GO:0000145"(exocyst)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035493"(SNARE complex assembly)|go:"GO:0035542"(regulation of SNARE complex assembly)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR001388(Synaptobrevin)|interpro:IPR028258|interpro:IPR037821|interpro:IPR037822|interpro:IPR042855|refseq:NP_001291405.1|refseq:NP_001291406.1|refseq:NP_054897.4|refseq:XP_016876720.1|refseq:XP_016876721.1|refseq:XP_016876722.1|refseq:XP_016876723.1|refseq:XP_016876724.1|refseq:XP_016876725.1|refseq:XP_016876726.1|refseq:XP_016876727.1|refseq:XP_016876728.1|refseq:XP_016876729.1|refseq:XP_016876730.1|refseq:XP_016876731.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:swwriJpkyEkYE6UDMsT9BNxHJ+89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7Z2W4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-922540|uniprotkb:Q8TAJ3|uniprotkb:Q96N79|uniprotkb:Q9H8R9|uniprotkb:Q9P0Y7|uniprotkb:Q8IW57|uniprotkb:A4D1R2|uniprotkb:A4D1S4|ensembl:ENSP00000242351 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zcchv_human(display_long)|uniprotkb:Inactive Poly [ADP-ribose] polymerase 13(gene name synonym)|uniprotkb:ZC3HAV1(gene name)|psi-mi:ZC3HAV1(display_short)|uniprotkb:ZC3HDC2(gene name synonym)|uniprotkb:PRO1677(orf name)|uniprotkb:Zinc finger CCCH domain-containing protein 2(gene name synonym)|uniprotkb:Zinc finger antiviral protein(gene name synonym)|uniprotkb:ADP-ribosyltransferase diphtheria toxin-like 13(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_064504.2|refseq:NP_078901.3|ensembl:ENSG00000105939(gene)|ensembl:ENST00000242351(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006471"(protein ADP-ribosylation)|go:"GO:0009615"(response to virus)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032728"(positive regulation of interferon-beta production)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051607"(defense response to virus)|go:"GO:0061014"(positive regulation of mRNA catabolic process)|go:"GO:1900246"(positive regulation of RIG-I signaling pathway)|interpro:IPR000571(Zinc finger, CCCH-type)|interpro:IPR004170(WWE)|interpro:IPR012317("Poly(ADP-ribose) polymerase, catalytic region")|interpro:IPR036388|interpro:IPR037197|interpro:IPR040954|interpro:IPR041360|mint:Q7Z2W4|rcsb pdb:2X5Y|rcsb pdb:4X52|rcsb pdb:6UEI|rcsb pdb:6UEJ|reactome:R-HSA-6802952|dip:DIP-37896N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:iJy4W/YX/vVXGbFd+GnfoKlo8aA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O96013 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-713738|uniprotkb:Q8N4E1|uniprotkb:Q8NCH5|uniprotkb:Q8NDE3|uniprotkb:Q9BU33|uniprotkb:Q9ULS8|uniprotkb:B4DGG6|ensembl:ENSP00000351049|ensembl:ENSP00000353625|ensembl:ENSP00000469413 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pak4_human(display_long)|uniprotkb:p21-activated kinase 4(gene name synonym)|uniprotkb:PAK4(gene name)|psi-mi:PAK4(display_short)|uniprotkb:KIAA1142(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N rcsb pdb:4FIF|rcsb pdb:4FIG|rcsb pdb:4FIH|rcsb pdb:4FII|rcsb pdb:4FIJ|rcsb pdb:4JDH|rcsb pdb:4JDI|rcsb pdb:4JDJ|rcsb pdb:4JDK|rcsb pdb:4L67|rcsb pdb:4NJD|rcsb pdb:4O0V|rcsb pdb:4O0X|rcsb pdb:4O0Y|rcsb pdb:4XBR|rcsb pdb:4XBU|rcsb pdb:5BMS|rcsb pdb:5I0B|rcsb pdb:5UPK|rcsb pdb:5UPL|rcsb pdb:5VED|rcsb pdb:5VEE|rcsb pdb:5VEF|rcsb pdb:5XVA|rcsb pdb:5XVF|rcsb pdb:5XVG|rcsb pdb:5ZJW|rcsb pdb:6WLX|rcsb pdb:6WLY|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|rcsb pdb:4FIE|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013420|reactome:R-HSA-9013423|ensembl:ENSG00000130669(gene)|ensembl:ENST00000358301(transcript)|ensembl:ENST00000360442(transcript)|ensembl:ENST00000593690(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0016477"(cell migration)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:2000352"(negative regulation of endothelial cell apoptotic process)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR036936|mint:O96013|go:"GO:0032147"(activation of protein kinase activity)|rcsb pdb:2BVA|rcsb pdb:2CDZ|rcsb pdb:2J0I|rcsb pdb:2OV2|rcsb pdb:2Q0N|rcsb pdb:2X4Z|rcsb pdb:4APP|refseq:NP_001014831.1|refseq:NP_001014832.1|refseq:NP_001014834.1|refseq:NP_001014835.1|refseq:NP_005875.1|refseq:XP_011524618.1|refseq:XP_011524619.1|refseq:XP_011524620.1|refseq:XP_011524621.1|refseq:XP_011524622.1|dip:DIP-39742N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:8i8hHt/Taj+czkueFRAMhdiMkYw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95208 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11081732|uniprotkb:Q9H7Z2|uniprotkb:O95207|uniprotkb:Q52LD0|uniprotkb:E9PBC2|uniprotkb:B3KRX8|uniprotkb:A8MTV8|uniprotkb:Q9UPT7|intact:EBI-28966811|ensembl:ENSP00000320543 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:epn2_human(display_long)|uniprotkb:EPN2(gene name)|psi-mi:EPN2(display_short)|uniprotkb:EPS-15-interacting protein 2(gene name synonym)|uniprotkb:KIAA1065(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000320543|ensembl:ENST00000347697|ensembl:ENSP00000261495|ensembl:ENST00000395618|ensembl:ENSP00000378980|ensembl:ENST00000395620|ensembl:ENSP00000378982|refseq:NP_001096134.1|refseq:NP_055779.2|refseq:NP_683723.2|ensembl:ENSG00000072134(gene)|ensembl:ENST00000314728(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030128"(clathrin coat of endocytic vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:1903671"(negative regulation of sprouting angiogenesis)|interpro:IPR003903(Ubiquitin interacting motif)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR027319|reactome:R-HSA-8856825|reactome:R-HSA-8856828 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:B6ilWrQ6NMO4qLklAv+ModftRk49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13442 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1390763|uniprotkb:Q92906|uniprotkb:D6W5S5|ensembl:ENSP00000222968 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:hap28_human(display_long)|uniprotkb:PDGF-associated protein(gene name synonym)|uniprotkb:PDGFA-associated protein 1(gene name synonym)|uniprotkb:PDAP1(gene name)|psi-mi:PDAP1(display_short)|uniprotkb:HASPP28(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055706.1|ensembl:ENSG00000106244(gene)|ensembl:ENST00000350498(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR019380|interpro:IPR039876|mint:Q13442|reactome:R-HSA-6798695 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:8oY/0PM5kBr34vOdRXuGjIVFMgU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q86SQ0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2798483|uniprotkb:Q68CY3|uniprotkb:Q8NCU5|uniprotkb:Q6NT98|uniprotkb:Q59EA8|uniprotkb:A5PKZ3|uniprotkb:Q8N8U8|uniprotkb:Q8NAB1|ensembl:ENSP00000377502|ensembl:ENSP00000405405 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:phlb2_human(display_long)|uniprotkb:LL5B(gene name synonym)|uniprotkb:Protein LL5-beta(gene name synonym)|uniprotkb:PHLDB2(gene name)|psi-mi:PHLDB2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001127909.1|refseq:NP_001127910.1|refseq:NP_001127911.1|refseq:NP_665696.1|ensembl:ENSG00000144824(gene)|ensembl:ENST00000393925(transcript)|ensembl:ENST00000431670(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010470"(regulation of gastrulation)|go:"GO:0010717"(regulation of epithelial to mesenchymal transition)|go:"GO:0031252"(cell leading edge)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045180"(basal cortex)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0051895"(negative regulation of focal adhesion assembly)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:1904261"(positive regulation of basement membrane assembly involved in embryonic body morphogenesis)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR037810|go:"GO:1903690"(negative regulation of wound healing, spreading of epidermal cells)|dip:DIP-42196N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:T5YIJ7WjxQlZKWAd/28wh3Znui89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9P266 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-6874715|ensembl:ENSP00000364526|uniprotkb:Q5HYA7|uniprotkb:Q5T992|uniprotkb:Q86WZ9|uniprotkb:Q9BYJ2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:jcad_human(display_long)|uniprotkb:JCAD(gene name)|psi-mi:JCAD(display_short)|uniprotkb:KIAA1462(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000364526|refseq:XP_011517910.1|ensembl:ENSG00000165757(gene)|ensembl:ENST00000375377(transcript)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0032587"(ruffle membrane)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:1900748"(positive regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1903589"(positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|interpro:IPR028221|refseq:NP_065899.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:OvmF2tJEt3Vy2Za67BHf6cRHDX89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15223 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1771314|uniprotkb:O75465|uniprotkb:Q2M3D3|uniprotkb:Q9HBE6|uniprotkb:Q9HBW2|ensembl:ENSP00000264025 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nect1_human(display_long)|uniprotkb:NECTIN1(gene name)|psi-mi:NECTIN1(display_short)|uniprotkb:HVEC(gene name synonym)|uniprotkb:Herpes virus entry mediator C(gene name synonym)|uniprotkb:Herpesvirus Ig-like receptor(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 1(gene name synonym)|uniprotkb:PRR1(gene name synonym)|uniprotkb:PVRL1(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002846.3|refseq:NP_976030.1|refseq:NP_976031.1|dip:DIP-40302N|ensembl:ENSG00000110400(gene)|ensembl:ENST00000264025(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0002934"(desmosome organization)|go:"GO:0005576"(extracellular region)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0006826"(iron ion transport)|go:"GO:0006955"(immune response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007157"(heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0007411"(axon guidance)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019062"(virion attachment to host cell)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0030425"(dendrite)|go:"GO:0032584"(growth cone membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0046790"(virion binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070166"(enamel mineralization)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:1902414"(protein localization to cell junction)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033314|interpro:IPR036179|interpro:IPR041849|interpro:IPR041850|rcsb pdb:3ALP|rcsb pdb:3SKU|rcsb pdb:3U82|rcsb pdb:3U83|rcsb pdb:4FMF|rcsb pdb:4MYW|reactome:R-HSA-418990|reactome:R-HSA-420597 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/KqZN5Vhyc6Qrih7IyHnkN8nsaE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P29317 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-702104|uniprotkb:Q8N3Z2|uniprotkb:B5A968|intact:EBI-28989000|ensembl:ENSP00000351209 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:epha2_human(display_long)|uniprotkb:Tyrosine-protein kinase receptor ECK(gene name synonym)|uniprotkb:Epithelial cell kinase(gene name synonym)|uniprotkb:EPHA2(gene name)|psi-mi:EPHA2(display_short)|uniprotkb:ECK(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004422.2|ensembl:ENSP00000351209|dip:DIP-96N|ensembl:ENSG00000142627(gene)|ensembl:ENST00000358432(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002043"(blood vessel endothelial cell proliferation involved in sprouting angiogenesis)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0005005"(transmembrane-ephrin receptor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006954"(inflammatory response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007275"(multicellular organism development)|go:"GO:0007411"(axon guidance)|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0009986"(cell surface)|go:"GO:0010591"(regulation of lamellipodium assembly)|go:"GO:0014028"(notochord formation)|go:"GO:0016477"(cell migration)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0019838"(growth factor binding)|go:"GO:0021915"(neural tube development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0031256"(leading edge membrane)|go:"GO:0031258"(lamellipodium membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032682"(negative regulation of chemokine production)|go:"GO:0033598"(mammary gland epithelial cell proliferation)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0043005"(neuron projection)|go:"GO:0043235"(receptor complex)|go:"GO:0043491"(protein kinase B signaling)|go:"GO:0043535"(regulation of blood vessel endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0046058"(cAMP metabolic process)|go:"GO:0046849"(bone remodeling)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0048320"(axial mesoderm formation)|go:"GO:0048870"(cell motility)|go:"GO:0050830"(defense response to Gram-positive bacterium)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060035"(notochord cell development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060444"(branching involved in mammary gland duct morphogenesis)|go:"GO:0070160"(tight junction)|go:"GO:0070309"(lens fiber cell morphogenesis)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070848"(response to growth factor)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1901491"(negative regulation of lymphangiogenesis)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904238"(pericyte cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001090(Ephrin receptor, ligand binding)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR001426(Receptor tyrosine kinase, class V, conserved site)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR008979(Galactose-binding like)|interpro:IPR009030(Growth factor, receptor)|interpro:IPR011009(Protein kinase-like)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016257(Tyrosine-protein kinase, ephrin receptor)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR027936|interpro:IPR034263|interpro:IPR036116|mint:P29317|rcsb pdb:1MQB|rcsb pdb:2E8N|rcsb pdb:2K9Y|rcsb pdb:2KSO|rcsb pdb:2X10|rcsb pdb:2X11|rcsb pdb:3C8X|rcsb pdb:3CZU|rcsb pdb:3FL7|rcsb pdb:3HEI|rcsb pdb:3HPN|rcsb pdb:3KKA|rcsb pdb:3MBW|rcsb pdb:3MX0|rcsb pdb:3SKJ|rcsb pdb:4P2K|rcsb pdb:4PDO|rcsb pdb:4TRL|rcsb pdb:5EK7|rcsb pdb:5I9U|rcsb pdb:5I9V|rcsb pdb:5I9W|rcsb pdb:5I9X|rcsb pdb:5I9Y|rcsb pdb:5I9Z|rcsb pdb:5IA0|rcsb pdb:5IA1|rcsb pdb:5IA2|rcsb pdb:5IA3|rcsb pdb:5IA4|rcsb pdb:5IA5|rcsb pdb:5NJZ|rcsb pdb:5NK0|rcsb pdb:5NK1|rcsb pdb:5NK2|rcsb pdb:5NK3|rcsb pdb:5NK4|rcsb pdb:5NK5|rcsb pdb:5NK6|rcsb pdb:5NK7|rcsb pdb:5NK8|rcsb pdb:5NK9|rcsb pdb:5NKA|rcsb pdb:5NKB|rcsb pdb:5NKC|rcsb pdb:5NKD|rcsb pdb:5NKE|rcsb pdb:5NKF|rcsb pdb:5NKG|rcsb pdb:5NKH|rcsb pdb:5NKI|rcsb pdb:5NZ9|rcsb pdb:6B9L|rcsb pdb:6F7M|rcsb pdb:6F7N|rcsb pdb:6FNF|rcsb pdb:6FNG|rcsb pdb:6FNH|rcsb pdb:6HES|rcsb pdb:6HET|rcsb pdb:6HEU|rcsb pdb:6HEV|rcsb pdb:6HEW|rcsb pdb:6HEX|rcsb pdb:6HEY|rcsb pdb:6NJZ|rcsb pdb:6NK0|rcsb pdb:6NK1|rcsb pdb:6NK2|rcsb pdb:6NKP|rcsb pdb:6Q7B|rcsb pdb:6Q7C|rcsb pdb:6Q7D|rcsb pdb:6Q7E|rcsb pdb:6Q7F|rcsb pdb:6Q7G|rcsb pdb:6RW2|rcsb pdb:7B7N|rcsb pdb:7CZE|rcsb pdb:7CZF|rcsb pdb:7KJA|rcsb pdb:7KJB|rcsb pdb:7KJC|reactome:R-HSA-2682334|reactome:R-HSA-3928663|reactome:R-HSA-3928665|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013420|reactome:R-HSA-9013423|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9VFikLd4ftRmEyBpY0JHdpHINT09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q07157 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P05556 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-703066|intact:EBI-4289597|ensembl:ENSP00000303351|ensembl:ENSP00000379350|ensembl:ENSP00000398029|ensembl:ENSP00000404546|ensembl:ENSP00000502882|ensembl:ENSP00000503546|ensembl:ENSP00000503916|ensembl:ENSP00000504205|ensembl:ENSP00000504444|uniprotkb:Q7Z3V1|uniprotkb:Q8WUM6|uniprotkb:P78466|uniprotkb:P78467|uniprotkb:Q13089|uniprotkb:Q13090|uniprotkb:Q13091|uniprotkb:Q13212|uniprotkb:Q14622|uniprotkb:Q14647|uniprotkb:A8K6N2|uniprotkb:Q29RW2|uniprotkb:D3DRX9|uniprotkb:D3DRY3|uniprotkb:D3DRY4|uniprotkb:D3DRY5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:itb1_human(display_long)|uniprotkb:Fibronectin receptor subunit beta(gene name synonym)|uniprotkb:VLA-4 subunit beta(gene name synonym)|uniprotkb:ITGB1(gene name)|psi-mi:ITGB1(display_short)|uniprotkb:FNRB(gene name synonym)|uniprotkb:MDF2(gene name synonym)|uniprotkb:MSK12(gene name synonym)|uniprotkb:Glycoprotein IIa(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0001618"(virus receptor activity)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001708"(cell fate specification)|go:"GO:0001726"(ruffle)|go:"GO:0001968"(fibronectin binding)|go:"GO:0002020"(protease binding)|go:"GO:0002042"(cell migration involved in sprouting angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006968"(cellular defense response)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008354"(germ cell migration)|go:"GO:0008542"(visual learning)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010710"(regulation of collagen catabolic process)|go:"GO:0010763"(positive regulation of fibroblast migration)|go:"GO:0014704"(intercalated disc)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016020"(membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0023035"(CD40 signaling pathway)|go:"GO:0030027"(lamellipodium)|go:"GO:0030030"(cell projection organization)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030183"(B cell differentiation)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031589"(cell-substrate adhesion)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031623"(receptor internalization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033627"(cell adhesion mediated by integrin)|go:"GO:0033631"(cell-cell adhesion mediated by integrin)|go:"GO:0034113"(heterotypic cell-cell adhesion)|go:"GO:0034665"(integrin alpha1-beta1 complex)|go:"GO:0034666"(integrin alpha2-beta1 complex)|go:"GO:0034667"(integrin alpha3-beta1 complex)|go:"GO:0034668"(integrin alpha4-beta1 complex)|go:"GO:0034674"(integrin alpha5-beta1 complex)|go:"GO:0034677"(integrin alpha7-beta1 complex)|go:"GO:0034678"(integrin alpha8-beta1 complex)|go:"GO:0034680"(integrin alpha10-beta1 complex)|go:"GO:0034681"(integrin alpha11-beta1 complex)|go:"GO:0035024"(negative regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042383"(sarcolemma)|go:"GO:0042470"(melanosome)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043197"(dendritic spine)|go:"GO:0043235"(receptor complex)|go:"GO:0043236"(laminin binding)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045214"(sarcomere organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045596"(negative regulation of cell differentiation)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048333"(mesodermal cell differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048675"(axon extension)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050901"(leukocyte tethering or rolling)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051951"(positive regulation of glutamate uptake involved in transmission of nerve impulse)|go:"GO:0055007"(cardiac muscle cell differentiation)|go:"GO:0055037"(recycling endosome)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071404"(cellular response to low-density lipoprotein particle stimulus)|go:"GO:0071711"(basement membrane organization)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097386"(glial cell projection)|go:"GO:0098639"(collagen binding involved in cell-matrix adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099699"(integral component of synaptic membrane)|go:"GO:0150003"(regulation of spontaneous synaptic transmission)|go:"GO:0150103"(reactive gliosis)|go:"GO:1901979"(regulation of inward rectifier potassium channel activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:2000273"(positive regulation of signaling receptor activity)|go:"GO:2000811"(negative regulation of anoikis)|interpro:IPR002369(Integrin beta subunit, N-terminal)|interpro:IPR012896(Integrin beta subunit, tail)|interpro:IPR013111(EGF, extracellular)|interpro:IPR014836(Integrin beta subunit, cytoplasmic)|interpro:IPR015812(Integrin beta subunit)|interpro:IPR016201(Plexin-like fold)|interpro:IPR027071|interpro:IPR032695|interpro:IPR033760|interpro:IPR036349|interpro:IPR036465|interpro:IPR040622|mint:P05556|rcsb pdb:1K11|rcsb pdb:1LHA|rcsb pdb:3G9W|rcsb pdb:3T9K|rcsb pdb:3VI3|rcsb pdb:3VI4|rcsb pdb:4DX9|rcsb pdb:4WJK|rcsb pdb:4WK0|rcsb pdb:4WK2|rcsb pdb:4WK4|rcsb pdb:7CEB|rcsb pdb:7CEC|rcsb pdb:7NWL|reactome:R-HSA-1566948|reactome:R-HSA-1566977|reactome:R-HSA-198933|ensembl:ENSG00000150093(gene)|ensembl:ENST00000302278(transcript)|ensembl:ENST00000396033(transcript)|ensembl:ENST00000417122(transcript)|ensembl:ENST00000437302(transcript)|ensembl:ENST00000677999(transcript)|ensembl:ENST00000678701(transcript)|ensembl:ENST00000678943(transcript)|ensembl:ENST00000678952(transcript)|ensembl:ENST00000678989(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000132"(establishment of mitotic spindle orientation)|refseq:NP_002202.2|refseq:NP_391988.1|refseq:NP_596867.1|dip:DIP-312N|reactome:R-HSA-202733|reactome:R-HSA-210991|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000157|reactome:R-HSA-3000170|reactome:R-HSA-3000178|reactome:R-HSA-416700|reactome:R-HSA-445144|reactome:R-HSA-446343|reactome:R-HSA-447041|reactome:R-HSA-5663220|reactome:R-HSA-6785807|reactome:R-HSA-75892|reactome:R-HSA-8874081|reactome:R-HSA-8875513|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609690|reactome:R-HSA-9679191 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:FZ+lMRS6Zq07A8Lgmf5C6vEXUgM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P30041 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15056 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-748492|uniprotkb:A8K3R1|uniprotkb:D3DXF6|uniprotkb:D3DXF8|ensembl:ENSP00000265753 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:if4h_human(display_long)|uniprotkb:Williams-Beuren syndrome chromosomal region 1 protein(gene name synonym)|uniprotkb:EIF4H(gene name)|psi-mi:EIF4H(display_short)|uniprotkb:WBSCR1(gene name synonym)|uniprotkb:KIAA0038(gene name synonym)|uniprotkb:WSCR1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_071496.1|refseq:NP_114381.1|ensembl:ENSG00000106682(gene)|ensembl:ENST00000265753(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0019953"(sexual reproduction)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048589"(developmental growth)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034229|interpro:IPR035979|mint:Q15056|reactome:R-HSA-156827|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:dNPoAzwFD5lFwCMnRl0cbXM3j8s9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15231 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-6874731|uniprotkb:H0Y4M8|uniprotkb:Q8N1R8|uniprotkb:A4FTV3|uniprotkb:A6NME5|uniprotkb:B4DLE9|uniprotkb:B7Z771|uniprotkb:B8K2L9|uniprotkb:B8K2M0|uniprotkb:B8K2M1|uniprotkb:B8K2M2|uniprotkb:E9PFR6|uniprotkb:F5GXF7|uniprotkb:F5GZL4|uniprotkb:F8W8V7|uniprotkb:O00345|uniprotkb:Q9NSD2|ensembl:ENSP00000359291 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zn185_human(display_long)|uniprotkb:ZNF185(gene name)|psi-mi:ZNF185(display_short)|uniprotkb:LIM domain protein ZNF185(gene name synonym)|uniprotkb:P1-A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_005274788.1|refseq:XP_005274792.1|refseq:XP_005274794.1|refseq:XP_005274795.1|refseq:XP_005274798.1|refseq:XP_005274802.1|refseq:NP_001171577.1|refseq:NP_001171578.1|refseq:NP_001171580.1|refseq:NP_001171579.1|refseq:NP_001171581.1|refseq:NP_001171584.1|refseq:NP_009081.2|refseq:NP_001171586.1|ensembl:ENSG00000147394(gene)|ensembl:ENST00000370268(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0008270"(zinc ion binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0051015"(actin filament binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR030637 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:V5eEqPIaPI0Q6FWcJymXqsWg5Zo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P78318 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1055954|uniprotkb:Q8TAB2|ensembl:ENSP00000348784|ensembl:ENSP00000363661 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:igbp1_human(display_long)|uniprotkb:IGBP1(gene name)|psi-mi:IGBP1(display_short)|uniprotkb:IBP1(gene name synonym)|uniprotkb:CD79a-binding protein 1(gene name synonym)|uniprotkb:B-cell signal transduction molecule alpha 4(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-16(gene name synonym)|uniprotkb:Protein phosphatase 2/4/6 regulatory subunit(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001542.1|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0060632"(regulation of microtubule-based movement)|go:"GO:0070555"(response to interleukin-1)|interpro:IPR007304(TAP42-like protein)|interpro:IPR038511|mint:P78318|rcsb pdb:4IYP|ensembl:ENSG00000089289(gene)|ensembl:ENST00000342206(transcript)|ensembl:ENST00000356413(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0032873"(negative regulation of stress-activated MAPK cascade)|go:"GO:0034612"(response to tumor necrosis factor)|go:"GO:0035303"(regulation of dephosphorylation)|go:"GO:0042113"(B cell activation)|refseq:XP_016884978.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:N8w92upYivqH3rjdqNbAcIjDu7I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y266 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-357298|ensembl:ENSP00000319664|uniprotkb:Q5QP31|uniprotkb:Q5QP35|uniprotkb:Q9H0N2|uniprotkb:Q9Y2B6|intact:EBI-2555945 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nudc_human(display_long)|uniprotkb:NUDC(gene name)|psi-mi:NUDC(display_short)|uniprotkb:Nuclear distribution protein C homolog(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000090273(gene)|ensembl:ENST00000321265(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006457"(protein folding)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0030496"(midbody)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051301"(cell division)|go:"GO:0072686"(mitotic spindle)|interpro:IPR007052(CS domain)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR025934|interpro:IPR032572|interpro:IPR037898|mint:Q9Y266|rcsb pdb:3QOR|reactome:R-HSA-141444|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-5663220|reactome:R-HSA-68877|reactome:R-HSA-9648025|go:"GO:0007080"(mitotic metaphase plate congression)|reactome:R-HSA-9696270|refseq:NP_006591.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:e1Q+/+VhG73ljCc3+ibG+RZNQUM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P22061 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353343|uniprotkb:Q14661|uniprotkb:Q16556|uniprotkb:Q5VYC1|uniprotkb:Q5VYC2|uniprotkb:Q93061|uniprotkb:Q96II9|uniprotkb:Q99625|uniprotkb:Q9BQV7|uniprotkb:Q9BQV8|uniprotkb:Q9NP03|uniprotkb:A8K109|intact:EBI-2551555|uniprotkb:J3KP72|ensembl:ENSP00000356348|ensembl:ENSP00000420813 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pimt_human(display_long)|uniprotkb:PCMT1(gene name)|psi-mi:PCMT1(display_short)|uniprotkb:Protein-beta-aspartate methyltransferase(gene name synonym)|uniprotkb:Protein L-isoaspartyl/D-aspartyl methyltransferase(gene name synonym)|uniprotkb:L-isoaspartyl protein carboxyl methyltransferase(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001238978.1|refseq:NP_001238982.1|ensembl:ENSG00000120265(gene)|ensembl:ENST00000367378(transcript)|ensembl:ENST00000464889(transcript)|go:"GO:0004719"("protein-L-isoaspartate (D-aspartate) O-methyltransferase activity")|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006479"(protein methylation)|go:"GO:0030091"(protein repair)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|interpro:IPR000682("Protein-L-isoaspartate(D-aspartate) O-methyltransferase")|interpro:IPR029063|mint:P22061|rcsb pdb:1I1N|rcsb pdb:1KR5|reactome:R-HSA-5676934|refseq:NP_005380.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:wfsjVloc3sqDMXlvFAXQI6Fjilw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P07858 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-715062|uniprotkb:Q503A6|uniprotkb:Q96D87|uniprotkb:B3KRR5|uniprotkb:B3KQR5|ensembl:ENSP00000503300|ensembl:ENSP00000503435|ensembl:ENSP00000503487|ensembl:ENSP00000503513|ensembl:ENSP00000503578|ensembl:ENSP00000503608|ensembl:ENSP00000503652|ensembl:ENSP00000503674|ensembl:ENSP00000503858|ensembl:ENSP00000503909|ensembl:ENSP00000504161|ensembl:ENSP00000504226|ensembl:ENSP00000504336|ensembl:ENSP00000504480|ensembl:ENSP00000504638|ensembl:ENSP00000504659|ensembl:ENSP00000504797|ensembl:ENSP00000503280|ensembl:ENSP00000342070|ensembl:ENSP00000345672|ensembl:ENSP00000431143|ensembl:ENSP00000431518|ensembl:ENSP00000432077|ensembl:ENSP00000432244|ensembl:ENSP00000432408|ensembl:ENSP00000433215|ensembl:ENSP00000433379|ensembl:ENSP00000433929|ensembl:ENSP00000434217|ensembl:ENSP00000434725|ensembl:ENSP00000435074|ensembl:ENSP00000435105|ensembl:ENSP00000435260|ensembl:ENSP00000435886|ensembl:ENSP00000473301|ensembl:ENSP00000502963|ensembl:ENSP00000503006|ensembl:ENSP00000503052|ensembl:ENSP00000503078|ensembl:ENSP00000503174 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:catb_human(display_long)|uniprotkb:Cathepsin B1(gene name synonym)|uniprotkb:APP secretase(gene name synonym)|uniprotkb:CTSB(gene name)|psi-mi:CTSB(display_short)|uniprotkb:CPSB(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001899.1|refseq:NP_680090.1|refseq:NP_680091.1|refseq:NP_680092.1|refseq:NP_680093.1|refseq:XP_011542114.1|refseq:XP_016868586.1|refseq:XP_016868587.1|refseq:XP_016868588.1|refseq:XP_016868589.1|ensembl:ENST00000345125(transcript)|ensembl:ENST00000353047(transcript)|ensembl:ENST00000524654(transcript)|ensembl:ENST00000526481(transcript)|ensembl:ENST00000526645(transcript)|ensembl:ENST00000527215(transcript)|ensembl:ENST00000534382(transcript)|ensembl:ENST00000527243(transcript)|ensembl:ENST00000534510(transcript)|ensembl:ENST00000676691(transcript)|ensembl:ENST00000676755(transcript)|ensembl:ENST00000676825(transcript)|ensembl:ENST00000676843(transcript)|ensembl:ENST00000676952(transcript)|ensembl:ENST00000677082(transcript)|ensembl:ENST00000677366(transcript)|ensembl:ENST00000677415(transcript)|ensembl:ENST00000528965(transcript)|ensembl:ENST00000530296(transcript)|ensembl:ENST00000530640(transcript)|ensembl:ENST00000677418(transcript)|ensembl:ENST00000677544(transcript)|ensembl:ENST00000677650(transcript)|ensembl:ENST00000677671(transcript)|ensembl:ENST00000677819(transcript)|ensembl:ENST00000677873(transcript)|ensembl:ENST00000678092(transcript)|ensembl:ENST00000678145(transcript)|ensembl:ENST00000678242(transcript)|ensembl:ENST00000531089(transcript)|ensembl:ENST00000678357(transcript)|ensembl:ENST00000531502(transcript)|ensembl:ENST00000678615(transcript)|ensembl:ENST00000532392(transcript)|ensembl:ENST00000678929(transcript)|ensembl:ENST00000532656(transcript)|ensembl:ENST00000533455(transcript)|ensembl:ENST00000679051(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005622"(intracellular anatomical structure)|go:"GO:0005764"(lysosome)|go:"GO:0006508"(proteolysis)|go:"GO:0006590"(thyroid hormone generation)|go:"GO:0008233"(peptidase activity)|go:"GO:0008234"(cysteine-type peptidase activity)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030574"(collagen catabolic process)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0036021"(endolysosome lumen)|go:"GO:0042470"(melanosome)|go:"GO:0042981"(regulation of apoptotic process)|ensembl:ENST00000679128(transcript)|go:"GO:0043394"(proteoglycan binding)|ensembl:ENST00000679140(transcript)|go:"GO:0046697"(decidualization)|go:"GO:0004197"(cysteine-type endopeptidase activity)|go:"GO:0005518"(collagen binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0051603"(proteolysis involved in cellular protein catabolic process)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|ensembl:ENSG00000164733(gene)|interpro:IPR000169(Peptidase, cysteine peptidase active site)|interpro:IPR000668(Peptidase C1A, papain C-terminal)|interpro:IPR012599(Peptidase C1A, propeptide)|interpro:IPR025660|interpro:IPR025661|interpro:IPR038765|mint:P07858|rcsb pdb:1CSB|rcsb pdb:1GMY|rcsb pdb:1HUC|rcsb pdb:1PBH|rcsb pdb:2IPP|rcsb pdb:2PBH|rcsb pdb:3AI8|rcsb pdb:3CBJ|rcsb pdb:3CBK|rcsb pdb:3K9M|rcsb pdb:3PBH|rcsb pdb:5MBL|rcsb pdb:5MBM|rcsb pdb:6AY2|reactome:R-HSA-1442490|reactome:R-HSA-1679131|reactome:R-HSA-2022090|reactome:R-HSA-2132295|reactome:R-HSA-6798695|go:"GO:1904813"(ficolin-1-rich granule lumen)|refseq:XP_006716307.1|refseq:XP_006716308.1|dip:DIP-42785N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:TdxD7Gf4BmlJcfUSULihf9W3sKQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T0N5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-714058|uniprotkb:J3QSS4|uniprotkb:Q5T0N6|uniprotkb:Q6B097|uniprotkb:Q6P653|uniprotkb:Q6R4Q4|uniprotkb:Q9NXG1|ensembl:ENSP00000271234 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:fbp1l_human(display_long)|uniprotkb:Transducer of Cdc42-dependent actin assembly protein 1(gene name synonym)|uniprotkb:FNBP1L(gene name)|psi-mi:FNBP1L(display_short)|uniprotkb:TOCA1(gene name synonym)|uniprotkb:C1orf39(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001020119.1|refseq:NP_001157945.1|refseq:NP_060207.2|interpro:IPR030116|interpro:IPR031160|interpro:IPR035493|interpro:IPR035494|interpro:IPR036028|reactome:R-HSA-8856828|reactome:R-HSA-9013148|reactome:R-HSA-9013409|ensembl:ENSG00000137942(gene)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005938"(cell cortex)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006914"(autophagy)|go:"GO:0007165"(signal transduction)|go:"GO:0008289"(lipid binding)|go:"GO:0010324"(membrane invagination)|go:"GO:0016050"(vesicle organization)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0045296"(cadherin binding)|ensembl:ENST00000271234(transcript)|go:"GO:0051020"(GTPase binding)|go:"GO:0051491"(positive regulation of filopodium assembly)|go:"GO:0060271"(cilium assembly)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR011072(HR1 rho-binding repeat)|interpro:IPR027267 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yGpTAKXe5mYtBFc89aMiYFMy9RU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O43581 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10184345|uniprotkb:F5GZC2|uniprotkb:F5H126|uniprotkb:F5H1N2|uniprotkb:F5H6C1|uniprotkb:F5GZU9|uniprotkb:Q08AH6|ensembl:ENSP00000263846 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:syt7_human(display_long)|uniprotkb:SYT7(gene name)|psi-mi:SYT7(display_short)|uniprotkb:IPCA-7(gene name synonym)|uniprotkb:PCANAP7(gene name synonym)|uniprotkb:Prostate cancer-associated protein 7(gene name synonym)|uniprotkb:Synaptotagmin VII(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_005274440.1|refseq:XP_005274442.1|refseq:NP_001238994.1|refseq:NP_001287702.1|refseq:NP_004191.2|ensembl:ENSG00000011347(gene)|ensembl:ENST00000263846(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001778"(plasma membrane repair)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005777"(peroxisome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006909"(phagocytosis)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0014059"(regulation of dopamine secretion)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0017156"(calcium-ion regulated exocytosis)|go:"GO:0017158"(regulation of calcium ion-dependent exocytosis)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030276"(clathrin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0030672"(synaptic vesicle membrane)|go:"GO:0031045"(dense core granule)|go:"GO:0032009"(early phagosome)|go:"GO:0036465"(synaptic vesicle recycling)|go:"GO:0042995"(cell projection)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0046850"(regulation of bone remodeling)|go:"GO:0048791"(calcium ion-regulated exocytosis of neurotransmitter)|go:"GO:0050764"(regulation of phagocytosis)|go:"GO:0050796"(regulation of insulin secretion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070092"(regulation of glucagon secretion)|go:"GO:0070382"(exocytic vesicle)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0090119"(vesicle-mediated cholesterol transport)|go:"GO:0090385"(phagosome-lysosome fusion)|go:"GO:0099056"(integral component of presynaptic membrane)|go:"GO:1990926"(short-term synaptic potentiation)|go:"GO:1990927"(calcium ion regulated lysosome exocytosis)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001565(Synaptotagmin)|interpro:IPR015427(Synaptotagmin 7)|interpro:IPR035892|interpro:IPR037732|interpro:IPR037741|rcsb pdb:2D8K|reactome:R-HSA-6794361|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+0JvST8e4DotWKE4aPJf+hRIWls9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NW97 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-726044|uniprotkb:A8K819|intact:EBI-28982784|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tmm51_human(display_long)|uniprotkb:TMEM51(gene name)|psi-mi:TMEM51(display_short)|uniprotkb:C1orf72(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001129688.1|refseq:NP_001129689.1|refseq:NP_001129690.1|refseq:NP_060492.1|ensembl:ENSP00000365176|ensembl:ENSP00000365182|ensembl:ENSP00000383600|ensembl:ENSP00000394899|refseq:XP_011539978.1|refseq:NP_001306594.1|refseq:XP_005245976.1|ensembl:ENSG00000171729(gene)|ensembl:ENST00000376008(transcript)|ensembl:ENST00000376014(transcript)|ensembl:ENST00000400796(transcript)|ensembl:ENST00000428417(transcript)|go:"GO:0016021"(integral component of membrane)|interpro:IPR029265|refseq:XP_016857079.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:D+zPUZqRR9fLJ2nvkP/jFdArrR89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BQ89 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1752811|uniprotkb:D3DVW2|uniprotkb:Q5R1M7|ensembl:ENSP00000246100|ensembl:ENSP00000354163|ensembl:ENSP00000371365|ensembl:ENSP00000371367|ensembl:ENSP00000445228 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:f110a_human(display_long)|uniprotkb:FAM110A(gene name)|psi-mi:FAM110A(display_short)|uniprotkb:C20orf55(gene name synonym)|uniprotkb:F10(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011527683.1|refseq:NP_001035812.1|refseq:NP_113612.1|refseq:NP_997004.1|refseq:NP_001276074.1|refseq:NP_001276075.1|refseq:NP_001276076.1|ensembl:ENSG00000125898(gene)|ensembl:ENST00000246100(transcript)|ensembl:ENST00000304189(transcript)|ensembl:ENST00000381939(transcript)|ensembl:ENST00000381941(transcript)|ensembl:ENST00000541082(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|interpro:IPR025739|interpro:IPR025740|interpro:IPR025741 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fwxpzV+6TSnqE7Wl8IjgEswrV9I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6EMK4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10249550|uniprotkb:Q6UXL4|uniprotkb:Q96CX1|uniprotkb:Q6UXL5|ensembl:ENSP00000306864|ensembl:ENSP00000481884 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vasn_human(display_long)|uniprotkb:VASN(gene name)|psi-mi:VASN(display_short)|uniprotkb:Protein slit-like 2(gene name synonym)|uniprotkb:SLITL2(gene name synonym)|uniprotkb:UNQ314/PRO357/PRO1282(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_612449.2|ensembl:ENSG00000168140(gene)|ensembl:ENSG00000274334(gene)|ensembl:ENST00000622615(transcript)|go:"GO:0005615"(extracellular space)|go:"GO:0005739"(mitochondrion)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030512"(negative regulation of transforming growth factor beta receptor signaling pathway)|go:"GO:0031012"(extracellular matrix)|go:"GO:0045296"(cadherin binding)|go:"GO:0050431"(transforming growth factor beta binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071461"(cellular response to redox state)|interpro:IPR000372(Leucine-rich repeat, cysteine-rich flanking region, N-terminal)|interpro:IPR000483(Cysteine-rich flanking region, C-terminal)|interpro:IPR000742(EGF-like, type 3)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR032675|interpro:IPR036116|ensembl:ENST00000304735(transcript)|dip:DIP-46245N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:k2oqBzbaF9IC/NW7ybgvNhbsryE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UNF0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-742503|uniprotkb:O95921|uniprotkb:Q96HV9|uniprotkb:Q9H0D3|uniprotkb:Q9NPN1|uniprotkb:Q9Y4V2|ensembl:ENSP00000385040|ensembl:ENSP00000385372|ensembl:ENSP00000263246 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pacn2_human(display_long)|uniprotkb:PACSIN2(gene name)|psi-mi:PACSIN2(display_short)|uniprotkb:Syndapin-II(gene name synonym)|uniprotkb:Syndapin-2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001171899.1|refseq:NP_001171900.1|refseq:NP_009160.2|refseq:XP_005261376.1|refseq:XP_016884053.1|ensembl:ENST00000263246(transcript)|ensembl:ENST00000402229(transcript)|ensembl:ENST00000403744(transcript)|go:"GO:0005215"(transporter activity)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|ensembl:ENSG00000100266(gene)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0016607"(nuclear speck)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0032587"(ruffle membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045806"(negative regulation of endocytosis)|go:"GO:0048858"(cell projection morphogenesis)|go:"GO:0050804"(modulation of chemical synaptic transmission)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0070836"(caveola assembly)|go:"GO:0072584"(caveolin-mediated endocytosis)|go:"GO:0097320"(plasma membrane tubulation)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001060(Cdc15/Fes/CIP4)|interpro:IPR001452(Src homology-3)|interpro:IPR027267|interpro:IPR028521|interpro:IPR031160|interpro:IPR035743|interpro:IPR036028|interpro:IPR037453|mint:Q9UNF0|rcsb pdb:3ABH|rcsb pdb:3ACO|rcsb pdb:3HAJ|rcsb pdb:3Q0K|reactome:R-HSA-8856828 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:oEGsyQlsPg61RRGLjBdPGKDmkXc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WWI1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350367|uniprotkb:O15462|uniprotkb:O95346|uniprotkb:Q9UKC1|uniprotkb:Q9UQM5|uniprotkb:Q9Y6A7|uniprotkb:Q5TBK6|uniprotkb:E9PLH4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lmo7_human(display_long)|uniprotkb:LMO7(gene name)|psi-mi:LMO7(display_short)|uniprotkb:FBX20(gene name synonym)|uniprotkb:FBXO20(gene name synonym)|uniprotkb:KIAA0858(gene name synonym)|uniprotkb:F-box only protein 20(gene name synonym)|uniprotkb:LOMP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005349.3|refseq:NP_056667.2|refseq:NP_001293009.1|go:"GO:0004842"(ubiquitin-protein transferase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0009986"(cell surface)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0023051"(regulation of signaling)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001715(Calponin-like actin-binding)|go:"GO:0000151"(ubiquitin ligase complex)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR003096(SM22/calponin)|interpro:IPR029978|interpro:IPR031865|interpro:IPR036034|interpro:IPR036872|rcsb pdb:2EAQ|reactome:R-HSA-8951664|reactome:R-HSA-983168|ensembl:ENST00000341547|ensembl:ENSP00000342112|ensembl:ENSG00000136153|refseq:NP_001317512.1|mint:Q8WWI1|dip:DIP-33107N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:d8c3oZaqaloIUBqxgvpNI3PP2fU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O00192 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11793353|uniprotkb:B7WNV2|ensembl:ENSP00000263207 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:arvc_human(display_long)|uniprotkb:ARVCF(gene name)|psi-mi:ARVCF(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001661.1|refseq:XP_006724310.1|refseq:XP_011528482.1|ensembl:ENSG00000099889(gene)|ensembl:ENST00000263207(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007275"(multicellular organism development)|go:"GO:0016339"(calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules)|go:"GO:0045296"(cadherin binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028444|go:"GO:0005622"(intracellular anatomical structure) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:4KnpTqkW4GzlJSWyMSoP0wWSoQ89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95292 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1188298|uniprotkb:O95293|uniprotkb:Q9P0H0|uniprotkb:A2A2F2|ensembl:ENSP00000417175 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vapb_human(display_long)|uniprotkb:VAPB(gene name)|psi-mi:VAPB(display_short)|uniprotkb:UNQ484/PRO983(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001182606.1|refseq:NP_004729.1|ensembl:ENSG00000124164(gene)|ensembl:ENST00000475243(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0008017"(microtubule binding)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019048"(modulation by virus of host process)|go:"GO:0019899"(enzyme binding)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0033149"(FFAT motif binding)|go:"GO:0036498"(IRE1-mediated unfolded protein response)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044790"(suppression of viral release by host)|go:"GO:0044791"(obsolete positive regulation by host of viral release from host cell)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0044829"(positive regulation by host of viral genome replication)|go:"GO:0044830"(modulation by host of viral RNA genome replication)|go:"GO:0045070"(positive regulation of viral genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0061817"(endoplasmic reticulum-plasma membrane tethering)|go:"GO:0090114"(COPII-coated vesicle budding)|go:"GO:0090158"(endoplasmic reticulum membrane organization)|interpro:IPR000535(Major sperm protein)|interpro:IPR008962(PapD-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR016763(Vesicle-associated membrane protein)|mint:O95292|rcsb pdb:2MDK|rcsb pdb:3IKK|reactome:R-HSA-1660661|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|dip:DIP-39816N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+TuApjAmnGF1UZonXIsrPaIN4Ak9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UBF2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1045840|uniprotkb:A6NH74|uniprotkb:Q54AC3|uniprotkb:Q8WVW8|ensembl:ENSP00000402346|uniprotkb:Q2NLA0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:copg2_human(display_long)|uniprotkb:Gamma-2-coat protein(gene name synonym)|uniprotkb:COPG2(gene name)|psi-mi:COPG2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001276962.1|refseq:NP_036265.3|ensembl:ENSG00000158623(gene)|ensembl:ENST00000425248(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006890"(retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum)|go:"GO:0006891"(intra-Golgi vesicle-mediated transport)|go:"GO:0009306"(protein secretion)|go:"GO:0030126"(COPI vesicle coat)|go:"GO:0030133"(transport vesicle)|go:"GO:0030426"(growth cone)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR002553(Clathrin/coatomer adaptor, adaptin-like, N-terminal)|interpro:IPR009028(Clathrin/coatomer adaptor, adaptin-like, appendage, C-terminal subdomain)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR012295(Beta2-adaptin/TATA-box binding, C-terminal)|interpro:IPR013040(Coatomer, gamma subunit, appendage, Ig-like subdomain)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR017106(Coatomer, gamma subunit)|interpro:IPR032154|interpro:IPR037067|mint:Q9UBF2|reactome:R-HSA-6807878|reactome:R-HSA-6811434|interpro:IPR013041(Clathrin/coatomer adaptor, adaptin-like, appendage, Ig-like subdomain) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:VEvct8z8lwNWbLs2GFPrKwk1GpE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8N3D4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2834588|uniprotkb:Q8TB89|uniprotkb:Q9H7M7|ensembl:ENSP00000312671 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:eh1l1_human(display_long)|uniprotkb:EHBP1L1(gene name)|psi-mi:EHBP1L1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000173442(gene)|ensembl:ENST00000309295(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR019448|interpro:IPR022735|interpro:IPR029928|interpro:IPR036872|refseq:NP_001092879.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:A49ma5uVQHbpAMd99czZVg2Kkfw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P07737 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-713780|ensembl:ENSP00000225655|uniprotkb:Q53Y44 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:prof1_human(display_long)|uniprotkb:Profilin I(gene name synonym)|uniprotkb:PFN1(gene name)|psi-mi:PFN1(display_short)|uniprotkb:Epididymis tissue protein Li 184a(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000108518(gene)|ensembl:ENST00000225655(transcript)|go:"GO:0000774"(adenyl-nucleotide exchange factor activity)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001843"(neural tube closure)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030837"(negative regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032232"(negative regulation of actin filament bundle assembly)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0060074"(synapse maturation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0072562"(blood microparticle)|go:"GO:0098885"(modification of postsynaptic actin cytoskeleton)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR005454(Profilin, Mammalian)|interpro:IPR005455(Profilin, plant)|interpro:IPR027310|interpro:IPR029892|interpro:IPR036140|mint:P07737|rcsb pdb:1AWI|rcsb pdb:1CF0|rcsb pdb:1CJF|rcsb pdb:1FIK|rcsb pdb:1FIL|rcsb pdb:1PFL|rcsb pdb:2PAV|rcsb pdb:2PBD|rcsb pdb:3CHW|rcsb pdb:4X1L|rcsb pdb:4X1M|rcsb pdb:4X25|rcsb pdb:6NAS|rcsb pdb:6NBE|rcsb pdb:6NBW|reactome:R-HSA-114608|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|reactome:R-HSA-4086400|reactome:R-HSA-5663220|reactome:R-HSA-376176|refseq:NP_005013.1|dip:DIP-30N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:CncaC5RMylvzFLhqzpS+VbhQn6I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60292 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2559690|uniprotkb:Q2TV87|intact:EBI-28973263|ensembl:ENSP00000222345 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:si1l3_human(display_long)|uniprotkb:SIPA1L3(gene name)|psi-mi:SIPA1L3(display_short)|uniprotkb:KIAA0545(gene name synonym)|uniprotkb:SPAL3(gene name synonym)|uniprotkb:SPA-1-like protein 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000222345|refseq:XP_011524959.1|refseq:NP_055888.1|ensembl:ENSG00000105738(gene)|ensembl:ENST00000222345(transcript)|go:"GO:0001654"(eye development)|go:"GO:0001725"(stress fiber)|go:"GO:0002244"(hematopoietic progenitor cell differentiation)|go:"GO:0003382"(epithelial cell morphogenesis)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0045177"(apical part of cell)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090162"(establishment of epithelial cell polarity)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000331(Rap/ran-GAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR021818|interpro:IPR031204|interpro:IPR035974|interpro:IPR036034|mint:O60292|go:"GO:0061689"(tricellular tight junction)|refseq:XP_005258728.1|refseq:XP_016882006.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:IzfxQ79AL5Y4lieFeMcvEYmPJu49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6Y7W6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-765394|uniprotkb:O75137|uniprotkb:Q7Z2Z8|uniprotkb:Q7Z3I2|uniprotkb:Q96HU4|uniprotkb:Q9NV82|uniprotkb:B9EG55|intact:EBI-10969943|uniprotkb:A6H8W4|uniprotkb:E9PBB0|ensembl:ENSP00000362664|ensembl:ENSP00000386537 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ggyf2_human(display_long)|uniprotkb:Trinucleotide repeat-containing gene 15 protein(gene name synonym)|uniprotkb:GIGYF2(gene name)|psi-mi:GIGYF2(display_short)|uniprotkb:KIAA0642(gene name synonym)|uniprotkb:TNRC15(gene name synonym)|uniprotkb:PERQ2(gene name synonym)|uniprotkb:PERQ amino acid-rich with GYF domain-containing protein 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001096616.1|refseq:NP_056390.2|refseq:NP_001096617.1|refseq:NP_001096618.1|ensembl:ENSG00000204120(gene)|ensembl:ENST00000373563(transcript)|ensembl:ENST00000409547(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007631"(feeding behavior)|go:"GO:0008344"(adult locomotory behavior)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016441"(posttranscriptional gene silencing)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0021522"(spinal cord motor neuron differentiation)|go:"GO:0031571"(mitotic G1 DNA damage checkpoint signaling)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043204"(perikaryon)|go:"GO:0044267"(cellular protein metabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048873"(homeostasis of number of cells within a tissue)|go:"GO:0050881"(musculoskeletal movement)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0061157"(mRNA destabilization)|go:"GO:0070064"(proline-rich region binding)|go:"GO:1990635"(proximal dendrite)|interpro:IPR003169(GYF)|interpro:IPR035445|rcsb pdb:5NVL|rcsb pdb:5NVM|mint:Q6Y7W6 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:LCnAT/BvynGfhb1p3KMftXk8S3Q9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q86VR7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-27077432|ensembl:ENSP00000335623 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vs10l_human(display_long)|uniprotkb:VSIG10L(gene name)|psi-mi:VSIG10L(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000186806(gene)|ensembl:ENST00000335624(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0016021"(integral component of membrane)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|refseq:NP_001157394.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:E5Tm1K7whEgxXCWyHQJ4ZA/Naxc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y2D5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1754555|uniprotkb:Q9UG26|uniprotkb:B1ALX9|uniprotkb:B2RTU4|uniprotkb:B3KQ00|uniprotkb:B4DTZ2|uniprotkb:B7ZW07|uniprotkb:B9EJB5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:akap2_human(display_long)|uniprotkb:AKAP2(gene name)|psi-mi:AKAP2(display_short)|uniprotkb:KIAA0920(gene name synonym)|uniprotkb:Protein kinase A-anchoring protein 2(gene name synonym)|uniprotkb:AKAP-KL(gene name synonym)|uniprotkb:PRKA2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001004065.2|refseq:NP_001130034.1|refseq:NP_001185585.1|refseq:NP_009134.1|refseq:NP_671492.1|interpro:IPR029304 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xfHb6tD0ToXJPHpl4MlbKczjzSg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P27448 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-707595|uniprotkb:O60219|uniprotkb:Q8TB41|uniprotkb:Q8WX83|uniprotkb:Q96RG1|uniprotkb:Q9UMY9|uniprotkb:Q9UN34|uniprotkb:Q86TT8|uniprotkb:A0A0A0MQR8|uniprotkb:A0A0A0MST9|uniprotkb:A0A0A0MT23|ensembl:ENSP00000411397 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mark3_human(display_long)|uniprotkb:Cdc25C-associated protein kinase 1(gene name synonym)|uniprotkb:C-TAK1(gene name synonym)|uniprotkb:Serine/threonine-protein kinase p78(gene name synonym)|uniprotkb:Ser/Thr protein kinase PAR-1(gene name synonym)|uniprotkb:Protein kinase STK10(gene name synonym)|uniprotkb:MARK3(gene name)|psi-mi:MARK3(display_short)|uniprotkb:CTAK1(gene name synonym)|uniprotkb:EMK2(gene name synonym)|uniprotkb:ELKL motif kinase 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001122390.2|refseq:NP_001122391.2|refseq:NP_001122392.2|refseq:NP_001122393.2|refseq:NP_002367.5|dip:DIP-34637N|ensembl:ENSG00000075413(gene)|ensembl:ENST00000429436(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0030425"(dendrite)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036289"(peptidyl-serine autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|interpro:IPR033628|mint:P27448|rcsb pdb:2QNJ|rcsb pdb:3FE3|rcsb pdb:7O94|reactome:R-HSA-5673000|reactome:R-HSA-5674135|reactome:R-HSA-5675221|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:YoMdp32OqT0OCgUUBwxSEHmA+vs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BY89 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-8796741|intact:EBI-28980779|ensembl:ENSP00000351207|ensembl:ENSP00000385152|uniprotkb:B7ZW08|uniprotkb:Q5THZ5|uniprotkb:B0QYF2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:k1671_human(display_long)|uniprotkb:KIAA1671(gene name)|psi-mi:KIAA1671(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000197077(gene)|ensembl:ENST00000358431(transcript)|ensembl:ENST00000406486(transcript)|interpro:IPR032764|interpro:IPR040006|ensembl:ENSP00000351207|ensembl:ENST00000401395|ensembl:ENSP00000385377|ensembl:ENSP00000385152|refseq:XP_005261850.1|refseq:XP_005261851.1|refseq:NP_001138678.1|refseq:XP_006724409.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7mCSVXo/8Z2MUHqsxKKXrBvOe749606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P53367 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2808808|uniprotkb:Q9Y2X6|uniprotkb:Q3SYL4|uniprotkb:B4DS69|uniprotkb:Q2M2X4|ensembl:ENSP00000296557|ensembl:ENSP00000395083 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:arfp1_human(display_long)|uniprotkb:ARFIP1(gene name)|psi-mi:ARFIP1(display_short)|uniprotkb:ADP-ribosylation factor-interacting protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011530171.1|refseq:NP_001020764.1|refseq:NP_001020766.1|refseq:NP_055262.1|refseq:XP_011530172.1|refseq:NP_001274360.1|refseq:NP_001274361.1|refseq:NP_001274362.1|ensembl:ENSG00000164144(gene)|ensembl:ENST00000353617(transcript)|ensembl:ENST00000451320(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:1905280"(negative regulation of retrograde transport, endosome to Golgi)|interpro:IPR010504(Arfaptin-like)|interpro:IPR027267|interpro:IPR030793|interpro:IPR030798|mint:P53367 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:KEZ1eqEIdGfgFYIlc3WlNvqg9/89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T0Z8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-16774533|ensembl:ENSP00000341368|uniprotkb:A6NI05 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cf132_human(display_long)|uniprotkb:C6orf132(gene name)|psi-mi:C6orf132(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000341368|ensembl:ENST00000356542|ensembl:ENSP00000348941|ensembl:ENSG00000188112(gene)|ensembl:ENST00000341865(transcript)|refseq:NP_001157918.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:U7ZihSwE4CaPOOv/UdC4JphzA5Y9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5M775 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350473|uniprotkb:Q5IBP1|uniprotkb:Q5IBP2|uniprotkb:Q5IBP3|uniprotkb:Q5IBP4|uniprotkb:Q5M772|uniprotkb:Q5M773|uniprotkb:Q5M774|uniprotkb:Q86XT8|uniprotkb:Q8N4U4|uniprotkb:Q8WU84|uniprotkb:Q9HCQ3|uniprotkb:B4DHH0|ensembl:ENSP00000261503|ensembl:ENSP00000378898|ensembl:ENSP00000502924|ensembl:ENSP00000503971|ensembl:ENSP00000504211|uniprotkb:B7WNS8|intact:EBI-2556892 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cytsb_human(display_long)|uniprotkb:Nuclear structure protein 5(gene name synonym)|uniprotkb:Sperm antigen HCMOGT-1(gene name synonym)|uniprotkb:SPECC1(gene name)|psi-mi:SPECC1(display_short)|uniprotkb:CYTSB(gene name synonym)|uniprotkb:Sperm antigen with calponin homology and coiled-coil domains 1(gene name synonym)|uniprotkb:NSP5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001028725.1|refseq:NP_001028726.1|refseq:NP_001028727.1|refseq:NP_001230367.1|refseq:NP_001230368.1|refseq:NP_690868.3|ensembl:ENSG00000128487(gene)|ensembl:ENST00000261503(transcript)|ensembl:ENST00000395527(transcript)|ensembl:ENST00000677914(transcript)|ensembl:ENST00000679058(transcript)|ensembl:ENST00000679255(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0016020"(membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR036872|mint:Q5M775|interpro:IPR001715(Calponin-like actin-binding)|refseq:XP_016880814.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:iF+19RpfJDyn5whTFnPmDxxECz09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15942 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-444225|ensembl:ENSP00000324422|ensembl:ENSP00000494798|uniprotkb:Q6I9S4|uniprotkb:A4D2G6|uniprotkb:B4DQX7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zyx_human(display_long)|uniprotkb:Zyxin-2(gene name synonym)|uniprotkb:ZYX(gene name)|psi-mi:ZYX(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000159840(gene)|ensembl:ENSG00000285443(gene)|ensembl:ENST00000322764(transcript)|ensembl:ENST00000646695(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0046872"(metal ion binding)|go:"GO:0050727"(regulation of inflammatory response)|go:"GO:0071346"(cellular response to interferon-gamma)|interpro:IPR001781(Zinc finger, LIM-type)|go:"GO:0043149"(stress fiber assembly)|refseq:NP_001010972.1|refseq:NP_003452.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:4UC6NVZHDUrTy4sPhz7e7RpPwho9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q53SF7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2835780|uniprotkb:A6NMZ3|uniprotkb:Q7Z3I6|uniprotkb:Q6IQ33|uniprotkb:Q9Y2I3|uniprotkb:Q9BRH4|uniprotkb:Q9UG88|ensembl:ENSP00000364607|ensembl:ENSP00000498242 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cobl1_human(display_long)|uniprotkb:COBLL1(gene name)|psi-mi:COBLL1(display_short)|uniprotkb:KIAA0977(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055715.3|refseq:NP_001265387.1|refseq:NP_001265389.1|refseq:NP_001265390.1|ensembl:ENSG00000082438(gene)|ensembl:ENST00000375458(transcript)|ensembl:ENST00000652658(transcript)|go:"GO:0003785"(actin monomer binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR019025|interpro:IPR039895|rcsb pdb:2DAJ - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:L7pIsPU2e9KYMTn0alEaL0+5sV09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NQC3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-715945|intact:EBI-1753019|uniprotkb:O94962|uniprotkb:Q9BXG5|uniprotkb:Q9H212|uniprotkb:Q9H3I3|uniprotkb:Q9UQ42|uniprotkb:Q9Y293|uniprotkb:Q9Y2Y7|uniprotkb:Q9Y5U6|intact:EBI-1958210|intact:EBI-1056082|uniprotkb:Q7L7Q8|uniprotkb:Q96B16|intact:EBI-28967519|ensembl:ENSP00000337838|uniprotkb:Q7L7Q5|uniprotkb:Q7L7Q6|uniprotkb:Q8IUA4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rtn4_human(display_long)|uniprotkb:Neurite outgrowth inhibitor(gene name synonym)|uniprotkb:Foocen(gene name synonym)|uniprotkb:Neuroendocrine-specific protein(gene name synonym)|uniprotkb:Neuroendocrine-specific protein C homolog(gene name synonym)|uniprotkb:RTN-x(gene name synonym)|uniprotkb:Reticulon-5(gene name synonym)|uniprotkb:RTN4(gene name)|psi-mi:RTN4(display_short)|uniprotkb:KIAA0886(gene name synonym)|uniprotkb:NOGO(gene name synonym)|uniprotkb:My043(orf name)|uniprotkb:SP1507(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000317610|ensembl:ENSP00000322147|ensembl:ENSP00000337838|ensembl:ENST00000357376|ensembl:ENSP00000349944|ensembl:ENST00000357732|ensembl:ENSP00000350365|ensembl:ENST00000394609|ensembl:ENSP00000378107|ensembl:ENST00000394611|ensembl:ENSP00000378109|ensembl:ENST00000404909|ensembl:ENSP00000385650|ensembl:ENST00000405240|ensembl:ENSP00000384471|refseq:NP_008939.1|refseq:NP_065393.1|refseq:NP_722550.1|refseq:NP_997403.1|refseq:NP_997404.1|ensembl:ENSG00000115310(gene)|ensembl:ENST00000337526(transcript)|go:"GO:0001825"(blastocyst formation)|go:"GO:0002523"(leukocyte migration involved in inflammatory response)|go:"GO:0003723"(RNA binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0007413"(axonal fasciculation)|go:"GO:0010634"(positive regulation of epithelial cell migration)|go:"GO:0014069"(postsynaptic density)|go:"GO:0021801"(cerebral cortex radial glia-guided migration)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030517"(negative regulation of axon extension)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0033601"(positive regulation of mammary gland epithelial cell proliferation)|go:"GO:0034165"(positive regulation of toll-like receptor 9 signaling pathway)|go:"GO:0035022"(positive regulation of Rac protein signal transduction)|go:"GO:0035441"(cell migration involved in vasculogenesis)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0042995"(cell projection)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0050821"(protein stabilization)|go:"GO:0051292"(nuclear pore complex assembly)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060317"(cardiac epithelial to mesenchymal transition)|go:"GO:0060907"(positive regulation of macrophage cytokine production)|go:"GO:0061462"(protein localization to lysosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0071782"(endoplasmic reticulum tubular network)|go:"GO:0071786"(endoplasmic reticulum tubular network organization)|go:"GO:0071787"(endoplasmic reticulum tubular network formation)|go:"GO:0090156"(cellular sphingolipid homeostasis)|go:"GO:0098826"(endoplasmic reticulum tubular network membrane)|go:"GO:0120078"(cell adhesion involved in sprouting angiogenesis)|go:"GO:1902430"(negative regulation of amyloid-beta formation)|go:"GO:1902624"(positive regulation of neutrophil migration)|go:"GO:1905523"(positive regulation of macrophage migration)|go:"GO:1905552"(positive regulation of protein localization to endoplasmic reticulum)|go:"GO:1905580"(positive regulation of ERBB3 signaling pathway)|go:"GO:1905653"(positive regulation of artery morphogenesis)|go:"GO:1990809"(endoplasmic reticulum tubular network membrane organization)|go:"GO:2000172"(regulation of branching morphogenesis of a nerve)|go:"GO:2000347"(positive regulation of hepatocyte proliferation)|go:"GO:2001213"(negative regulation of vasculogenesis)|interpro:IPR003388(Reticulon)|mint:Q9NQC3|rcsb pdb:2G31|rcsb pdb:2JV5|reactome:R-HSA-193634|refseq:XP_005264491.1|refseq:NP_001308788.1|refseq:NP_001308789.1|refseq:NP_001308790.1|refseq:NP_001308791.1|refseq:NP_001308792.1|refseq:NP_001308833.1|refseq:XP_016860007.1|refseq:XP_016860008.1|dip:DIP-42003N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:uhivTNOPdC7+q81CliY0Ozu0EwA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5VWQ8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2871881|uniprotkb:B0QZB1|uniprotkb:Q96SE1|uniprotkb:Q9C0C0|uniprotkb:A6H8V2|uniprotkb:A6NHI9|uniprotkb:Q8TDL2|uniprotkb:G3XA90|intact:EBI-28974929|ensembl:ENSP00000386183 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dab2p_human(display_long)|uniprotkb:DAB2IP(gene name)|psi-mi:DAB2IP(display_short)|uniprotkb:AF9Q34(gene name synonym)|uniprotkb:AIP1(gene name synonym)|uniprotkb:KIAA1743(gene name synonym)|uniprotkb:ASK-interacting protein 1(gene name synonym)|uniprotkb:DOC-2/DAB-2 interactive protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000259371|ensembl:ENSP00000259371|ensembl:ENST00000309989|ensembl:ENSP00000310827|ensembl:ENSP00000386183|refseq:XP_011516572.1|refseq:XP_011516573.1|refseq:NP_115941.2|refseq:NP_619723.1|refseq:XP_016869789.1|refseq:XP_005251776.1|dip:DIP-41721N|ensembl:ENSG00000136848(gene)|ensembl:ENST00000408936(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000185"(obsolete activation of MAPKKK activity)|go:"GO:0001525"(angiogenesis)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005123"(death receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006954"(inflammatory response)|go:"GO:0007049"(cell cycle)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0008625"(extrinsic apoptotic signaling pathway via death domain receptors)|go:"GO:0010596"(negative regulation of endothelial cell migration)|go:"GO:0010633"(negative regulation of epithelial cell migration)|go:"GO:0010719"(negative regulation of epithelial to mesenchymal transition)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014067"(negative regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021814"(cell motility involved in cerebral cortex radial glia guided migration)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR021887|interpro:IPR023152|interpro:IPR030403|interpro:IPR035892|interpro:IPR039360|reactome:R-HSA-5658442|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031435"(mitogen-activated protein kinase kinase kinase binding)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0032809"(neuronal cell body membrane)|go:"GO:0034144"(negative regulation of toll-like receptor 4 signaling pathway)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0034620"(cellular response to unfolded protein)|go:"GO:0035148"(tube formation)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036312"(phosphatidylinositol 3-kinase regulatory subunit binding)|go:"GO:0036324"(vascular endothelial growth factor receptor-2 signaling pathway)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0040008"(regulation of growth)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043184"(vascular endothelial growth factor receptor 2 binding)|go:"GO:0043254"(regulation of protein-containing complex assembly)|go:"GO:0043407"(negative regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0043548"(phosphatidylinositol 3-kinase binding)|go:"GO:0043553"(negative regulation of phosphatidylinositol 3-kinase activity)|go:"GO:0044257"(cellular protein catabolic process)|go:"GO:0044300"(cerebellar mossy fiber)|go:"GO:0044301"(climbing fiber)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046330"(positive regulation of JNK cascade)|go:"GO:0046580"(negative regulation of Ras protein signal transduction)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0070059"(intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071347"(cellular response to interleukin-1)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071889"(14-3-3 protein binding)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:0071902"(positive regulation of protein serine/threonine kinase activity)|go:"GO:0072577"(endothelial cell apoptotic process)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0090129"(positive regulation of synapse maturation)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900744"(regulation of p38MAPK cascade)|go:"GO:1900747"(negative regulation of vascular endothelial growth factor signaling pathway)|go:"GO:1901800"(positive regulation of proteasomal protein catabolic process)|go:"GO:1903363"(negative regulation of cellular protein catabolic process)|go:"GO:1903896"(positive regulation of IRE1-mediated unfolded protein response)|go:"GO:1990032"(parallel fiber)|go:"GO:1990597"(AIP1-IRE1 complex)|go:"GO:2001224"(positive regulation of neuron migration)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|go:"GO:0070317"(negative regulation of G0 to G1 transition) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:JbFRnZ1gUoRogZz+WvJYHA57Ius9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P46937 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1044059|uniprotkb:Q7Z574|uniprotkb:Q8IUY9|ensembl:ENSP00000282441|intact:EBI-28992622|uniprotkb:B7ZA01|uniprotkb:E3WEB5|uniprotkb:E3WEB6|uniprotkb:E9PRV2|uniprotkb:F5H202|uniprotkb:K0KQ18|uniprotkb:K0KYZ8|uniprotkb:K0L195|uniprotkb:K0L1G3|uniprotkb:B4DTY1 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:yap1_human(display_long)|uniprotkb:YAP1(gene name)|psi-mi:YAP1(display_short)|uniprotkb:YAP65(gene name synonym)|uniprotkb:Protein yorkie homolog(gene name synonym)|uniprotkb:Yes-associated protein YAP65 homolog(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001269026.1|ensembl:ENST00000282441(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0001570"(vasculogenesis)|go:"GO:0001674"(female germ cell nucleus)|go:"GO:0001829"(trophectodermal cell differentiation)|go:"GO:0001894"(tissue homeostasis)|go:"GO:0003015"(heart process)|go:"GO:0003143"(embryonic heart tube morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0003714"(transcription corepressor activity)|ensembl:ENSG00000137693(gene)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008283"(cell population proliferation)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010837"(regulation of keratinocyte proliferation)|go:"GO:0016020"(membrane)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030857"(negative regulation of epithelial cell differentiation)|go:"GO:0030903"(notochord development)|go:"GO:0032570"(response to progesterone)|go:"GO:0033148"(positive regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035019"(somatic stem cell population maintenance)|go:"GO:0035329"(hippo signaling)|go:"GO:0042060"(wound healing)|go:"GO:0045599"(negative regulation of fat cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045747"(positive regulation of Notch signaling pathway)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0005634"(nucleus)|go:"GO:0048339"(paraxial mesoderm development)|go:"GO:0048368"(lateral mesoderm development)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050847"(progesterone receptor signaling pathway)|refseq:NP_001123617.1|refseq:NP_001181973.1|refseq:NP_001181974.1|go:"GO:0070102"(interleukin-6-mediated signaling pathway)|go:"GO:0071300"(cellular response to retinoic acid)|go:"GO:0071480"(cellular response to gamma radiation)|go:"GO:0072091"(regulation of stem cell proliferation)|go:"GO:0072307"(regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:0140552"(TEAD-YAP complex)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902018"(negative regulation of cilium assembly)|go:"GO:1902459"(positive regulation of stem cell population maintenance)|go:"GO:1904036"(negative regulation of epithelial cell apoptotic process)|go:"GO:2000737"(negative regulation of stem cell differentiation)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR036020|mint:P46937|rcsb pdb:1JMQ|rcsb pdb:1K5R|rcsb pdb:1K9Q|rcsb pdb:1K9R|rcsb pdb:2LAW|rcsb pdb:2LAX|rcsb pdb:2LAY|rcsb pdb:2LTV|rcsb pdb:2LTW|rcsb pdb:3KYS|rcsb pdb:3MHR|rcsb pdb:4RE1|rcsb pdb:4REX|rcsb pdb:5OAQ|rcsb pdb:5YDX|rcsb pdb:5YDY|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6G8Q|rcsb pdb:6GE3|rcsb pdb:6GE4|rcsb pdb:6GE5|rcsb pdb:6GE6|rcsb pdb:6GEC|rcsb pdb:6GEE|rcsb pdb:6GEG|go:"GO:0070064"(proline-rich region binding)|rcsb pdb:6GEI|rcsb pdb:6GEK|rcsb pdb:6HIK|rcsb pdb:6HIL|rcsb pdb:6Q2X|reactome:R-HSA-1251985|reactome:R-HSA-2028269|reactome:R-HSA-2032785|reactome:R-HSA-8939236|reactome:R-HSA-8940973|reactome:R-HSA-8951671|reactome:R-HSA-9619665|go:"GO:0060045"(positive regulation of cardiac muscle cell proliferation)|go:"GO:0060242"(contact inhibition)|go:"GO:0060449"(bud elongation involved in lung branching)|go:"GO:0060487"(lung epithelial cell differentiation)|go:"GO:0060576"(intestinal epithelial cell development)|go:"GO:0061026"(cardiac muscle tissue regeneration)|go:"GO:0065003"(protein-containing complex assembly)|ensembl:ENSP00000282441|ensembl:ENST00000345877|ensembl:ENSP00000331023|ensembl:ENST00000524575|ensembl:ENSP00000435602|ensembl:ENST00000526343|refseq:NP_001269027.1|refseq:NP_001269028.1|refseq:NP_001269029.1|refseq:NP_001269030.1|ensembl:ENSP00000434134|ensembl:ENST00000531439|ensembl:ENSP00000431574|ensembl:ENSP00000487519|ensembl:ENST00000537274|ensembl:ENSP00000445635|ensembl:ENST00000615667|ensembl:ENSP00000478927|ensembl:ENST00000629586|dip:DIP-40839N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:bDNDhtCh5Qjdk1+PNM8Qb/340A09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UM54 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350606|uniprotkb:Q5TEM5|uniprotkb:Q5TEM6|uniprotkb:Q5TEM7|uniprotkb:Q9BZZ7|uniprotkb:Q9UEG2|uniprotkb:A6H8V4|uniprotkb:E1P540 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:myo6_human(display_long)|uniprotkb:MYO6(gene name)|psi-mi:MYO6(display_short)|uniprotkb:KIAA0389(gene name synonym)|uniprotkb:Unconventional myosin-6(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0051046"(regulation of secretion)|refseq:NP_004990.3|go:"GO:0000146"(microfilament motor activity)|go:"GO:0001726"(ruffle)|go:"GO:0003774"(cytoskeletal motor activity)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016461"(unconventional myosin complex)|go:"GO:0016591"(RNA polymerase II, holoenzyme)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0030050"(vesicle transport along actin filament)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030175"(filopodium)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0030665"(clathrin-coated vesicle membrane)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031941"(filamentous actin)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032587"(ruffle membrane)|go:"GO:0042472"(inner ear morphogenesis)|go:"GO:0042491"(inner ear auditory receptor cell differentiation)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043531"(ADP binding)|go:"GO:0045177"(apical part of cell)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005938"(cell cortex)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0007015"(actin filament organization)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001609(Myosin head, motor region)|interpro:IPR004009(Myosin, N-terminal, SH3-like)|interpro:IPR008989(Myosin S1 fragment, N-terminal)|interpro:IPR027417|interpro:IPR032412|interpro:IPR036114|interpro:IPR036961|rcsb pdb:2N0Z|rcsb pdb:2N10|rcsb pdb:2N11|go:"GO:0060001"(minus-end directed microfilament motor activity)|rcsb pdb:2N12|rcsb pdb:2N13|rcsb pdb:6E5N|rcsb pdb:6J56|reactome:R-HSA-190873|reactome:R-HSA-399719|reactome:R-HSA-9013418|reactome:R-HSA-9013420|reactome:R-HSA-9013422|refseq:NP_001287828.1|mint:Q9UM54|dip:DIP-33123N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:LYtnU7aRzVE/LDFhZgcK5IvahC09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NQU5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1053685|ensembl:ENSP00000260404|ensembl:ENSP00000401153|ensembl:ENSP00000406873|ensembl:ENSP00000439597|ensembl:ENSP00000453858|ensembl:ENSP00000456785|uniprotkb:A8K2G2|uniprotkb:B3KYB0|uniprotkb:G5E9R2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pak6_human(display_long)|uniprotkb:p21-activated kinase 6(gene name synonym)|uniprotkb:PAK-5(gene name synonym)|uniprotkb:PAK6(gene name)|psi-mi:PAK6(display_short)|uniprotkb:PAK5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0006355"(regulation of transcription, DNA-templated)|ensembl:ENSG00000137843(gene)|ensembl:ENST00000260404(transcript)|ensembl:ENST00000441369(transcript)|ensembl:ENST00000453867(transcript)|ensembl:ENST00000542403(transcript)|ensembl:ENST00000558658(transcript)|ensembl:ENST00000560346(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|refseq:NP_001263646.1|refseq:NP_001122100.1|refseq:NP_001122101.1|refseq:NP_064553.1|refseq:NP_001263647.1|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006915"(apoptotic process)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007612"(learning)|go:"GO:0007613"(memory)|go:"GO:0007626"(locomotory behavior)|go:"GO:0030054"(cell junction)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0043408"(regulation of MAPK cascade)|go:"GO:0045296"(cadherin binding)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140058"(neuron projection arborization)|go:"GO:1990138"(neuron projection extension)|interpro:IPR000095(PAK-box/P21-Rho-binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR033923|interpro:IPR035066|interpro:IPR036936|rcsb pdb:2C30|rcsb pdb:2ODB|rcsb pdb:4KS7|rcsb pdb:4KS8|rcsb pdb:6QDR|rcsb pdb:6QDS|reactome:R-HSA-428540|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013424 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:sLf1m1moEJrh+5QFw4V8UgWgxOQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BX66 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-433642|uniprotkb:A0AED4|uniprotkb:O43857|uniprotkb:Q7LBE5|uniprotkb:Q8IVK0|uniprotkb:Q8IVQ4|uniprotkb:Q96KF3|uniprotkb:Q96KF4|uniprotkb:Q9BX64|uniprotkb:Q9BX65|uniprotkb:Q9P2Q0|uniprotkb:Q9UFT2|uniprotkb:Q9UHN7|uniprotkb:Q9Y338|uniprotkb:A7MD40|uniprotkb:Q5T924|uniprotkb:D3DR42|uniprotkb:A6NEK3|uniprotkb:A6NID8|uniprotkb:A6NJS4|uniprotkb:Q5T923|uniprotkb:Q5T927|uniprotkb:Q5T928|uniprotkb:Q5T929|uniprotkb:Q5T930|uniprotkb:Q5T931|uniprotkb:Q5T932|ensembl:ENSP00000355136|ensembl:ENSP00000360293 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:srbs1_human(display_long)|uniprotkb:KIAA0894(gene name synonym)|uniprotkb:Ponsin(gene name synonym)|uniprotkb:c-Cbl-associated protein(gene name synonym)|uniprotkb:SH3 domain protein 5(gene name synonym)|uniprotkb:SH3P12(gene name synonym)|uniprotkb:SORBS1(gene name)|psi-mi:SORBS1(display_short)|uniprotkb:KIAA1296(gene name synonym)|uniprotkb:SH3D5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001030126.1|refseq:NP_001030127.1|refseq:NP_001030128.1|refseq:NP_001030129.1|refseq:NP_006425.2|refseq:NP_056200.1|refseq:NP_079267.1|refseq:XP_006717652.1|refseq:NP_001277223.1|refseq:NP_001277224.1|refseq:NP_001277225.1|refseq:NP_001277226.1|refseq:NP_001277227.1|rcsb pdb:2O9V|rcsb pdb:4LN2|rcsb pdb:4LNP|reactome:R-HSA-445355|ensembl:ENSG00000095637(gene)|ensembl:ENST00000361941(transcript)|ensembl:ENST00000371247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0016600"(flotillin complex)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0045121"(membrane raft)|go:"GO:0045725"(positive regulation of glycogen biosynthetic process)|go:"GO:0046326"(positive regulation of glucose import)|go:"GO:0046628"(positive regulation of insulin receptor signaling pathway)|go:"GO:0046889"(positive regulation of lipid biosynthetic process)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:0016363"(nuclear matrix)|interpro:IPR001452(Src homology-3)|interpro:IPR003127(Sorbin-like)|interpro:IPR035606|interpro:IPR035610|interpro:IPR035611|interpro:IPR036028|mint:Q9BX66|rcsb pdb:2DL3|rcsb pdb:2ECZ|rcsb pdb:2LJ0|rcsb pdb:2LJ1|rcsb pdb:2MOX|rcsb pdb:2O2W|rcsb pdb:2O31|rcsb pdb:2O9S - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:R2ONicSRiI7w0eCi4m4vbdPekL09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O00299 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000404037|ensembl:ENSP00000404589|ensembl:ENSP00000406088|ensembl:ENSP00000406335|ensembl:ENSP00000406968|ensembl:ENSP00000407429|ensembl:ENSP00000407791|ensembl:ENSP00000408094|ensembl:ENSP00000408357|ensembl:ENSP00000409247|ensembl:ENSP00000409979|ensembl:ENSP00000410965|ensembl:ENSP00000412217|ensembl:ENSP00000413330|ensembl:ENSP00000416211|ensembl:ENSP00000477623|ensembl:ENSP00000478930|ensembl:ENSP00000479501|ensembl:ENSP00000479808|ensembl:ENSP00000480256|ensembl:ENSP00000482255|ensembl:ENSP00000484581|ensembl:ENSP00000364934|ensembl:ENSP00000364935|ensembl:ENSP00000364940|ensembl:ENSP00000372896|ensembl:ENSP00000372897|ensembl:ENSP00000379229|ensembl:ENSP00000382926|ensembl:ENSP00000382931|ensembl:ENSP00000391395|ensembl:ENSP00000398056|ensembl:ENSP00000400280|ensembl:ENSP00000400532|ensembl:ENSP00000401292 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|ensembl:ENST00000375779(transcript)|ensembl:ENST00000375780(transcript)|ensembl:ENST00000375784(transcript)|ensembl:ENST00000383404(transcript)|ensembl:ENST00000383405(transcript)|ensembl:ENST00000395892(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072562"(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|go:"GO:0005634"(nucleus)|ensembl:ENSG00000206394(gene)|ensembl:ENSG00000213719(gene)|ensembl:ENSG00000223639(gene)|ensembl:ENSG00000226248(gene)|ensembl:ENSG00000226417(gene)|ensembl:ENSG00000226651(gene)|ensembl:ENSG00000230685(gene)|ensembl:ENST00000400052(transcript)|ensembl:ENST00000400058(transcript)|ensembl:ENST00000415179(transcript)|ensembl:ENST00000418285(transcript)|ensembl:ENST00000420458(transcript)|ensembl:ENST00000422167(transcript)|ensembl:ENST00000423055(transcript)|ensembl:ENST00000423143(transcript)|ensembl:ENST00000423804(transcript)|ensembl:ENST00000425464(transcript)|ensembl:ENST00000431921(transcript)|ensembl:ENST00000433916(transcript)|ensembl:ENST00000434202(transcript)|ensembl:ENST00000435242(transcript)|ensembl:ENST00000438708(transcript)|ensembl:ENST00000438750(transcript)|ensembl:ENST00000442045(transcript)|ensembl:ENST00000447338(transcript)|ensembl:ENST00000447369(transcript)|ensembl:ENST00000451546(transcript)|ensembl:ENST00000456863(transcript)|ensembl:ENST00000457485(transcript)|ensembl:ENST00000614673(transcript)|ensembl:ENST00000614982(transcript)|ensembl:ENST00000616760(transcript)|ensembl:ENST00000618288(transcript)|ensembl:ENST00000619727(transcript)|ensembl:ENST00000621055(transcript)|ensembl:ENST00000622613(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036282|interpro:IPR040079|mint:O00299|interpro:IPR036249|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75167 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1754409|uniprotkb:B2RWP7|uniprotkb:B4DN76|uniprotkb:B4DPB5|uniprotkb:B4DTH7|uniprotkb:A6NKP5|uniprotkb:A8MZC0|uniprotkb:Q5TFA0|uniprotkb:Q68DM2|uniprotkb:A7MCZ5|ensembl:ENSP00000391763 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:phar2_human(display_long)|uniprotkb:PHACTR2(gene name)|psi-mi:PHACTR2(display_short)|uniprotkb:C6orf56(gene name synonym)|uniprotkb:KIAA0680(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001093634.1|refseq:NP_001093635.1|refseq:NP_001093636.1|refseq:NP_055536.2|ensembl:ENSG00000112419(gene)|ensembl:ENST00000427704(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031092"(platelet alpha granule membrane)|interpro:IPR004018(RPEL repeat)|interpro:IPR029991|reactome:R-HSA-114608 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:T5ovG2OkUtZ5U3pVWGlm6r2L18s9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P42224 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1057697|uniprotkb:Q53S88|uniprotkb:Q53XW4|uniprotkb:B2RCA0|uniprotkb:Q9UDL5|uniprotkb:A8K989|uniprotkb:D2KFR8|uniprotkb:Q68D00|uniprotkb:D3DPI7|ensembl:ENSP00000354394|ensembl:ENSP00000386244|ensembl:ENSP00000388240|ensembl:ENSP00000438703 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stat1_human(display_long)|uniprotkb:STAT1(gene name)|psi-mi:STAT1(display_short)|uniprotkb:Transcription factor ISGF-3 components p91/p84(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_009330.1|refseq:NP_644671.1|rcsb pdb:1YVL|rcsb pdb:2KA6|rcsb pdb:3WWT|reactome:R-HSA-1059683|reactome:R-HSA-1169408|reactome:R-HSA-1433557|reactome:R-HSA-1839117|reactome:R-HSA-186763|reactome:R-HSA-6785807|reactome:R-HSA-877300|reactome:R-HSA-877312|reactome:R-HSA-8854691|reactome:R-HSA-8939902|reactome:R-HSA-8984722|reactome:R-HSA-8985947|reactome:R-HSA-9013508|reactome:R-HSA-9020956|reactome:R-HSA-9020958|reactome:R-HSA-909733|rcsb pdb:1BF5|reactome:R-HSA-9670439|reactome:R-HSA-9673767|reactome:R-HSA-9673770|reactome:R-HSA-9674555|reactome:R-HSA-9705462|reactome:R-HSA-982772|reactome:R-HSA-912694|refseq:XP_006712781.1|go:"GO:0003700"(DNA-binding transcription factor activity)|go:"GO:0005164"(tumor necrosis factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006952"(defense response)|go:"GO:0007259"(receptor signaling pathway via JAK-STAT)|go:"GO:0007584"(response to nutrient)|go:"GO:0008015"(blood circulation)|go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0010742"(macrophage derived foam cell differentiation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016922"(nuclear receptor binding)|ensembl:ENSG00000115415(gene)|ensembl:ENST00000361099(transcript)|ensembl:ENST00000409465(transcript)|ensembl:ENST00000415035(transcript)|ensembl:ENST00000540176(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000785"(chromatin)|go:"GO:0000978"(RNA polymerase II cis-regulatory region sequence-specific DNA binding)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0001937"(negative regulation of endothelial cell proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0044389"(ubiquitin-like protein ligase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045648"(positive regulation of erythrocyte differentiation)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0072162"(metanephric mesenchymal cell differentiation)|go:"GO:0072308"(negative regulation of metanephric nephron tubule epithelial cell differentiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990841"(promoter-specific chromatin binding)|interpro:IPR000980(SH2 motif)|interpro:IPR001217(STAT transcription factor, core)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|interpro:IPR008967(p53-like transcription factor, DNA-binding)|go:"GO:0046725"(negative regulation by virus of viral protein levels in host cell)|interpro:IPR012345(STAT transcription factor, DNA-binding, subdomain)|interpro:IPR013799(STAT transcription factor, protein interaction)|interpro:IPR013800(STAT transcription factor, all-alpha)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0051591"(response to cAMP)|go:"GO:0051607"(defense response to virus)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051770"(positive regulation of nitric-oxide synthase biosynthetic process)|go:"GO:0060333"(interferon-gamma-mediated signaling pathway)|go:"GO:0060337"(type I interferon signaling pathway)|go:"GO:0061326"(renal tubule development)|go:"GO:0070106"(interleukin-27-mediated signaling pathway)|go:"GO:0071346"(cellular response to interferon-gamma)|go:"GO:0071407"(cellular response to organic cyclic compound)|interpro:IPR013801(STAT transcription factor, DNA-binding)|interpro:IPR015988(STAT transcription factor, coiled coil)|interpro:IPR022752|go:"GO:0072136"(metanephric mesenchymal cell proliferation involved in metanephros development)|interpro:IPR035859|interpro:IPR036535|interpro:IPR036860|interpro:IPR038295|mint:P42224|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019899"(enzyme binding)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031730"(CCR5 chemokine receptor binding)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034097"(response to cytokine)|go:"GO:0035035"(histone acetyltransferase binding)|go:"GO:0035456"(response to interferon-beta)|go:"GO:0035458"(cellular response to interferon-beta)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042393"(histone binding)|dip:DIP-46140N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:a2ZnhdFZkctbjaXLpsYNJ3q5Cv49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14145 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-751001|uniprotkb:B3KPD5|uniprotkb:Q8WTX1|uniprotkb:Q6LEP0|uniprotkb:Q9BPY9|intact:EBI-28976014|ensembl:ENSP00000171111|ensembl:ENSP00000377245 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:keap1_human(display_long)|uniprotkb:Cytosolic inhibitor of Nrf2(gene name synonym)|uniprotkb:Kelch-like protein 19(gene name synonym)|uniprotkb:KEAP1(gene name)|psi-mi:KEAP1(display_short)|uniprotkb:INRF2(gene name synonym)|uniprotkb:KIAA0132(gene name synonym)|uniprotkb:KLHL19(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_036421.2|refseq:NP_987096.1|ensembl:ENSP00000171111|ensembl:ENSP00000377245|refseq:XP_011526754.1|refseq:XP_005260230.1|refseq:XP_005260231.1|dip:DIP-42134N|ensembl:ENSG00000079999(gene)|ensembl:ENST00000171111(transcript)|ensembl:ENST00000393623(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0006511"(ubiquitin-dependent protein catabolic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0016234"(inclusion body)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0030496"(midbody)|go:"GO:0031463"(Cul3-RING ubiquitin ligase complex)|go:"GO:0032436"(positive regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034451"(centriolar satellite)|go:"GO:0034599"(cellular response to oxidative stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0042994"(cytoplasmic sequestering of transcription factor)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0045604"(regulation of epidermal cell differentiation)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0097718"(disordered domain specific binding)|interpro:IPR000210(BTB/POZ-like)|interpro:IPR006652(Kelch repeat type 1)|interpro:IPR011333(BTB/POZ fold)|interpro:IPR011705(BTB/Kelch-associated)|interpro:IPR015915(Kelch-type beta propeller)|interpro:IPR017096(Kelch-like protein, gigaxonin)|interpro:IPR030563|mint:Q14145|rcsb pdb:1U6D|rcsb pdb:1ZGK|rcsb pdb:2FLU|rcsb pdb:3VNG|rcsb pdb:3VNH|rcsb pdb:3ZGC|rcsb pdb:3ZGD|rcsb pdb:4CXI|rcsb pdb:4CXJ|rcsb pdb:4CXT|rcsb pdb:4IFJ|rcsb pdb:4IFL|rcsb pdb:4IFN|rcsb pdb:4IN4|rcsb pdb:4IQK|rcsb pdb:4L7B|rcsb pdb:4L7C|rcsb pdb:4L7D|rcsb pdb:4N1B|rcsb pdb:4XMB|rcsb pdb:5DAD|rcsb pdb:5DAF|rcsb pdb:5F72|rcsb pdb:5GIT|rcsb pdb:5NLB|rcsb pdb:5WFL|rcsb pdb:5WFV|rcsb pdb:5WG1|rcsb pdb:5WHL|rcsb pdb:5WHO|rcsb pdb:5WIY|rcsb pdb:5X54|rcsb pdb:6FFM|rcsb pdb:6FMP|rcsb pdb:6FMQ|rcsb pdb:6HWS|rcsb pdb:6LRZ|rcsb pdb:6ROG|rcsb pdb:6SP1|rcsb pdb:6SP4|rcsb pdb:6T7V|rcsb pdb:6T7Z|rcsb pdb:6TG8|rcsb pdb:6TYM|rcsb pdb:6TYP|rcsb pdb:6UF0|rcsb pdb:6W66|rcsb pdb:6W67|rcsb pdb:6W68|rcsb pdb:6W69|rcsb pdb:6WCQ|rcsb pdb:6Z6A|rcsb pdb:7K28|rcsb pdb:7K29|rcsb pdb:7K2A|rcsb pdb:7K2B|rcsb pdb:7K2C|rcsb pdb:7K2D|rcsb pdb:7K2E|rcsb pdb:7K2F|rcsb pdb:7K2G|rcsb pdb:7K2H|rcsb pdb:7K2I|rcsb pdb:7K2J|rcsb pdb:7K2K|rcsb pdb:7K2L|rcsb pdb:7K2M|rcsb pdb:7K2N|rcsb pdb:7K2O|rcsb pdb:7K2P|rcsb pdb:7K2Q|rcsb pdb:7K2R|rcsb pdb:7K2S|reactome:R-HSA-5689880|reactome:R-HSA-8932339|reactome:R-HSA-8951664|reactome:R-HSA-983168|rcsb pdb:6V6Z - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3y/KqnUK+5nIyjhOEfkkthmP1OA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IZH2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-372406|uniprotkb:Q4G0S3|uniprotkb:Q68D88|uniprotkb:Q6AI24|uniprotkb:Q6MZS8|uniprotkb:Q86WS7|uniprotkb:Q8N8U4|uniprotkb:Q9UF39|ensembl:ENSP00000264951 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:xrn1_human(display_long)|uniprotkb:Strand-exchange protein 1 homolog(gene name synonym)|uniprotkb:XRN1(gene name)|psi-mi:XRN1(display_short)|uniprotkb:SEP1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_061874.3|refseq:NP_001269786.1|refseq:NP_001269788.1|ensembl:ENSG00000114127(gene)|ensembl:ENST00000264951(transcript)|go:"GO:0000932"(P-body)|go:"GO:0000956"(nuclear-transcribed mRNA catabolic process)|go:"GO:0002151"(G-quadruplex RNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0004534"(5'-3' exoribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016075"(rRNA catabolic process)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0030425"(dendrite)|go:"GO:0032211"(negative regulation of telomere maintenance via telomerase)|go:"GO:0033574"(response to testosterone)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045202"(synapse)|go:"GO:0051880"(G-quadruplex DNA binding)|go:"GO:0070034"(telomerase RNA binding)|go:"GO:0071028"(nuclear mRNA surveillance)|go:"GO:0071044"(histone mRNA catabolic process)|go:"GO:0071409"(cellular response to cycloheximide)|go:"GO:0090503"(RNA phosphodiester bond hydrolysis, exonucleolytic)|go:"GO:1905795"(cellular response to puromycin)|interpro:IPR004859(Putative 5-3 exonuclease)|interpro:IPR016494(5'-3' exoribonuclease 1)|interpro:IPR027073|interpro:IPR040992|interpro:IPR041106|interpro:IPR041385|interpro:IPR041412|reactome:R-HSA-430039|reactome:R-HSA-450385|reactome:R-HSA-450513|dip:DIP-31174N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Y5wskamFEhJ+vmrGjlw4nYHiWLg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UKK9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-721623|uniprotkb:Q6IAG0|uniprotkb:Q9UH49|uniprotkb:A8K516|ensembl:ENSP00000419628|ensembl:ENSP00000445116 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nudt5_human(display_long)|uniprotkb:Nucleoside diphosphate-linked moiety X motif 5(gene name synonym)|uniprotkb:YSA1H(gene name synonym)|uniprotkb:NUDT5(gene name)|psi-mi:NUDT5(display_short)|uniprotkb:HSPC115(orf name)|uniprotkb:8-oxo-dGDP phosphatase(gene name synonym)|uniprotkb:NUDIX5(gene name synonym)|uniprotkb:Nuclear ATP-synthesis protein NUDIX5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_054861.2|ensembl:ENSG00000165609(gene)|ensembl:ENST00000491614(transcript)|ensembl:ENST00000537776(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006753"(nucleoside phosphate metabolic process)|go:"GO:0009117"(nucleotide metabolic process)|go:"GO:0009191"(ribonucleoside diphosphate catabolic process)|go:"GO:0016779"(nucleotidyltransferase activity)|go:"GO:0019144"(ADP-sugar diphosphatase activity)|go:"GO:0019303"(D-ribose catabolic process)|go:"GO:0019693"(ribose phosphate metabolic process)|go:"GO:0030515"(snoRNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044715"(8-oxo-dGDP phosphatase activity)|go:"GO:0044716"(8-oxo-GDP phosphatase activity)|go:"GO:0047631"(ADP-ribose diphosphatase activity)|go:"GO:0055086"(nucleobase-containing small molecule metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990966"(ATP generation from poly-ADP-D-ribose)|interpro:IPR000086(NUDIX hydrolase, core)|interpro:IPR015797(NUDIX)|interpro:IPR020084|interpro:IPR020476|rcsb pdb:2DSB|rcsb pdb:2DSC|rcsb pdb:2DSD|rcsb pdb:3AC9|rcsb pdb:3ACA|rcsb pdb:3BM4|rcsb pdb:3L85|rcsb pdb:5NQR|rcsb pdb:5NWH|rcsb pdb:5QJ4|rcsb pdb:5QJ5|rcsb pdb:5QJ6|rcsb pdb:5QJ7|rcsb pdb:5QJ8|rcsb pdb:5QJ9|rcsb pdb:5QJA|rcsb pdb:5QJB|rcsb pdb:5QJC|rcsb pdb:5QJD|rcsb pdb:5QJE|rcsb pdb:5QJF|rcsb pdb:5QJG|rcsb pdb:5QJH|rcsb pdb:5QJI|rcsb pdb:5QJJ|rcsb pdb:5QJK|rcsb pdb:5QJL|rcsb pdb:5QJM|rcsb pdb:5QJN|rcsb pdb:5QJO|rcsb pdb:5QJP|rcsb pdb:5QJQ|rcsb pdb:5QJR|rcsb pdb:5QJS|rcsb pdb:5QJT|rcsb pdb:5QJU|rcsb pdb:5QJV|rcsb pdb:5QJW|rcsb pdb:5QJX|rcsb pdb:5QJY|rcsb pdb:5QJZ|rcsb pdb:5QK0|rcsb pdb:5QK1|rcsb pdb:5QK2|rcsb pdb:5QK3|rcsb pdb:5QK4|rcsb pdb:5QK5|rcsb pdb:5QKB|rcsb pdb:5QTL|rcsb pdb:5QTM|rcsb pdb:5QTN|rcsb pdb:5QTO|rcsb pdb:5QTP|rcsb pdb:5QTQ|rcsb pdb:5QTR|rcsb pdb:5QTS|rcsb pdb:6GRU|reactome:R-HSA-2393930|rcsb pdb:5QK6|rcsb pdb:5QK7|rcsb pdb:5QK8|rcsb pdb:5QK9|rcsb pdb:5QKA - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:jeBjAoLC9hGn34DKTP5QehZeZwM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q99439 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2961712|ensembl:ENSP00000263097|uniprotkb:Q92578|uniprotkb:A5D8U8|uniprotkb:D6W5X9|uniprotkb:A6NFI4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cnn2_human(display_long)|uniprotkb:CNN2(gene name)|psi-mi:CNN2(display_short)|uniprotkb:Calponin H2, smooth muscle(gene name synonym)|uniprotkb:Neutral calponin(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000064666(gene)|ensembl:ENST00000263097(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032970"(regulation of actin filament-based process)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042060"(wound healing)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0045296"(cadherin binding)|go:"GO:0050765"(negative regulation of phagocytosis)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029974|interpro:IPR036872|rcsb pdb:1WYN|reactome:R-HSA-6798695|reactome:R-HSA-8950505|refseq:NP_004359.1|refseq:NP_958434.1|refseq:NP_001290428.1|refseq:NP_001290430.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:64KRSh4MEocrTZ8EuTz9ni8ahhc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P23634 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1174388|uniprotkb:Q13450|uniprotkb:Q13452|uniprotkb:Q13455|uniprotkb:Q16817|uniprotkb:Q7Z3S1|uniprotkb:B1APW6|uniprotkb:B1APW5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:at2b4_human(display_long)|uniprotkb:Plasma membrane calcium ATPase isoform 4(gene name synonym)|uniprotkb:Plasma membrane calcium pump isoform 4(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 1(gene name synonym)|uniprotkb:ATP2B4(gene name)|psi-mi:ATP2B4(display_short)|uniprotkb:ATP2B2(gene name synonym)|uniprotkb:MXRA1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001001396.1|refseq:NP_001675.3|go:"GO:0003407"(neural retina development)|go:"GO:0005388"(P-type calcium transporter activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005901"(caveola)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0007283"(spermatogenesis)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010751"(negative regulation of nitric oxide mediated signal transduction)|go:"GO:0014832"(urinary bladder smooth muscle contraction)|go:"GO:0015085"(calcium ion transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0017080"(sodium channel regulator activity)|go:"GO:0019829"(ATPase-coupled cation transmembrane transporter activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0030018"(Z disc)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030315"(T-tubule)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030346"(protein phosphatase 2B binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034220"(ion transmembrane transport)|go:"GO:0036126"(sperm flagellum)|go:"GO:0036487"(nitric-oxide synthase inhibitor activity)|go:"GO:0043005"(neuron projection)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045121"(membrane raft)|go:"GO:0046872"(metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050998"(nitric-oxide synthase binding)|go:"GO:0051001"(negative regulation of nitric-oxide synthase activity)|go:"GO:0051480"(regulation of cytosolic calcium ion concentration)|go:"GO:0051599"(response to hydrostatic pressure)|go:"GO:0070588"(calcium ion transmembrane transport)|go:"GO:0070885"(negative regulation of calcineurin-NFAT signaling cascade)|go:"GO:0071872"(cellular response to epinephrine stimulus)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097228"(sperm principal piece)|go:"GO:0097553"(calcium ion transmembrane import into cytosol)|go:"GO:0098703"(calcium ion import across plasma membrane)|go:"GO:0098736"(negative regulation of the force of heart contraction)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099059"(integral component of presynaptic active zone membrane)|go:"GO:0140199"(negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1900082"(negative regulation of arginine catabolic process)|go:"GO:1901660"(calcium ion export)|go:"GO:1902083"(negative regulation of peptidyl-cysteine S-nitrosylation)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902548"(negative regulation of cellular response to vascular endothelial growth factor stimulus)|go:"GO:1902806"(regulation of cell cycle G1/S phase transition)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903243"(negative regulation of cardiac muscle hypertrophy in response to stress)|go:"GO:1903249"(negative regulation of citrulline biosynthetic process)|go:"GO:1903779"(regulation of cardiac conduction)|go:"GO:1905145"(cellular response to acetylcholine)|go:"GO:2000481"(positive regulation of cAMP-dependent protein kinase activity)|interpro:IPR001757(ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)|interpro:IPR004014(ATPase, P-type cation-transporter, N-terminal)|interpro:IPR006068(ATPase, P-type cation-transporter, C-terminal)|interpro:IPR006408(Calcium-translocating P-type ATPase, PMCA-type)|interpro:IPR008250(E1-E2 ATPase-associated region)|interpro:IPR018303|interpro:IPR022141|interpro:IPR023214|interpro:IPR023298|interpro:IPR023299|interpro:IPR036412|interpro:IPR044492|rcsb pdb:1CFF|rcsb pdb:2KNE|reactome:R-HSA-418359|reactome:R-HSA-5578775|reactome:R-HSA-936837|mint:P23634|dip:DIP-6128N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XAjzRea7vq4vsbCVKdZRYIWvfBM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NC51 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-523558|uniprotkb:Q8WUH0|uniprotkb:Q96SE2|uniprotkb:Q9BTY3|uniprotkb:Q9BUM4|uniprotkb:Q9Y367|uniprotkb:Q9Y4S3|uniprotkb:Q5VU19|intact:EBI-1058614|ensembl:ENSP00000360034|uniprotkb:Q5VU20|uniprotkb:Q5VU22 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pairb_human(display_long)|uniprotkb:PAI1 RNA-binding protein 1(gene name synonym)|uniprotkb:SERPINE1 mRNA-binding protein 1(gene name synonym)|uniprotkb:CGI-55(orf name)|uniprotkb:SERBP1(gene name)|psi-mi:SERBP1(display_short)|uniprotkb:PAIRBP1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000142864(gene)|ensembl:ENST00000370995(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003730"(mRNA 3'-UTR binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030578"(PML body organization)|go:"GO:0032183"(SUMO binding)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043488"(regulation of mRNA stability)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|interpro:IPR006861(Hyaluronan/mRNA binding protein)|interpro:IPR027205|interpro:IPR032381|interpro:IPR039764|mint:Q8NC51|rcsb pdb:4V6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|refseq:NP_001018077.1|refseq:NP_001018078.1|refseq:NP_001018079.1|refseq:NP_056455.3|dip:DIP-33819N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lVkIPRkoXs3B4Qop1pA2zG/RKlo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BZF9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350510|uniprotkb:Q14DD3|uniprotkb:Q8N3B8|uniprotkb:Q9HCL1|uniprotkb:Q9NWC6|uniprotkb:G3XAG2|uniprotkb:Q96NH6|intact:EBI-10977773|ensembl:ENSP00000314556 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:uaca_human(display_long)|uniprotkb:UACA(gene name)|psi-mi:UACA(display_short)|uniprotkb:KIAA1561(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001008225.1|refseq:NP_060473.2|dip:DIP-33117N|ensembl:ENSG00000137831(gene)|ensembl:ENST00000322954(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0043280"(positive regulation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097190"(apoptotic signaling pathway)|go:"GO:1901223"(negative regulation of NIK/NF-kappaB signaling)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR030227|interpro:IPR036770|mint:Q9BZF9|reactome:R-HSA-9013407|reactome:R-HSA-9627069 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:F58VkGk2DBsUUrB+wgknUFZhJ+E9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6T4R5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-6147838|uniprotkb:Q5J7Q1|uniprotkb:Q68DR5|uniprotkb:Q5J7Q0|uniprotkb:B7ZVX8|uniprotkb:E2DH69|ensembl:ENSP00000502262 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nhs_human(display_long)|uniprotkb:NHS(gene name)|psi-mi:NHS(display_short)|uniprotkb:Congenital cataracts and dental anomalies protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001278796.1|refseq:NP_001278797.1|refseq:NP_001129496.1|refseq:NP_938011.1|ensembl:ENSG00000188158(gene)|ensembl:ENST00000676302(transcript)|go:"GO:0002088"(lens development in camera-type eye)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR024845|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:HqtL7E5pe3UkCCbArDU0XY+HAW49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9ULH0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-716681|uniprotkb:A1L4N4|intact:EBI-2798329|uniprotkb:Q6MZU2|uniprotkb:Q9H889|uniprotkb:Q9H9E4|uniprotkb:Q9NT37|uniprotkb:Q9UF42|uniprotkb:Q4VC08|ensembl:ENSP00000256707 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:kdis_human(display_long)|uniprotkb:KIAA1250(gene name synonym)|uniprotkb:KIDINS220(gene name)|psi-mi:KIDINS220(display_short)|uniprotkb:ARMS(gene name synonym)|uniprotkb:Ankyrin repeat-rich membrane-spanning protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_065789.1|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019887"(protein kinase regulator activity)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000134313(gene)|ensembl:ENST00000256707(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0038180"(nerve growth factor signaling pathway)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|interpro:IPR002110(Ankyrin)|interpro:IPR011646(KAP P-loop)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR020683|interpro:IPR036770|mint:Q9ULH0|reactome:R-HSA-170984|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0wyaXuvXCqQTlfjuW4TAcIGmdlw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P14209 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-748547|uniprotkb:O00518|uniprotkb:Q6ICV7|uniprotkb:A6NIW1|ensembl:ENSP00000370588 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cd99_human(display_long)|uniprotkb:T-cell surface glycoprotein E2(gene name synonym)|uniprotkb:E2 antigen(gene name synonym)|uniprotkb:Protein MIC2(gene name synonym)|uniprotkb:12E7(gene name synonym)|uniprotkb:CD99(gene name)|psi-mi:CD99(display_short)|uniprotkb:MIC2(gene name synonym)|uniprotkb:MIC2X(gene name synonym)|uniprotkb:MIC2Y(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001116370.1|refseq:NP_002405.1|refseq:NP_001308296.1|refseq:NP_001308297.1|refseq:NP_001308298.1|ensembl:ENSG00000002586(gene)|ensembl:ENST00000381192(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0072683"(T cell extravasation)|go:"GO:2000391"(positive regulation of neutrophil extravasation)|interpro:IPR022078|reactome:R-HSA-198933|reactome:R-HSA-202733 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:g0uUrvPtgp5eBwP7RXnQa0Ij6GU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q70E73 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3940924|uniprotkb:Q9C0I2|uniprotkb:Q96Q37|ensembl:ENSP00000316543 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:raph1_human(display_long)|uniprotkb:RAPH1(gene name)|psi-mi:RAPH1(display_short)|uniprotkb:ALS2CR18(gene name synonym)|uniprotkb:ALS2CR9(gene name synonym)|uniprotkb:KIAA1681(gene name synonym)|uniprotkb:LPD(gene name synonym)|uniprotkb:PREL2(gene name synonym)|uniprotkb:RMO1(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 18 protein(gene name synonym)|uniprotkb:Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 9 protein(gene name synonym)|uniprotkb:Lamellipodin(gene name synonym)|uniprotkb:Proline-rich EVH1 ligand 2(gene name synonym)|uniprotkb:Protein RMO1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_976241.1|refseq:NP_998754.1|ensembl:ENST00000308091|ensembl:ENSP00000311293|ensembl:ENSP00000316543|ensembl:ENST00000418114|ensembl:ENSP00000396711|ensembl:ENST00000419464|ensembl:ENSP00000390578|ensembl:ENST00000423104|ensembl:ENSP00000397751|ensembl:ENST00000439222|ensembl:ENSP00000411138|ensembl:ENST00000453034|ensembl:ENSP00000406662|dip:DIP-61336N|ensembl:ENSG00000173166(gene)|ensembl:ENST00000319170(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016604"(nuclear body)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0048675"(axon extension)|interpro:IPR000159(Ras-association)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR029071|interpro:IPR039664|interpro:IPR039665|rcsb pdb:4GMV|rcsb pdb:4GN1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:gvrXafpck5vbLuP/cmMV69yJgzs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96DA0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-953824|ensembl:ENSP00000371715|ensembl:ENSP00000489035|uniprotkb:A6NIY1|uniprotkb:Q6UW28|uniprotkb:B2R4F6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zg16b_human(display_long)|uniprotkb:ZG16B(gene name)|psi-mi:ZG16B(display_short)|uniprotkb:UNQ773/PRO1567(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000634500(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0005615"(extracellular space)|go:"GO:0030246"(carbohydrate binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001229(Mannose-binding lectin)|interpro:IPR036404|rcsb pdb:3AQG|ensembl:ENSG00000283056(gene)|ensembl:ENST00000382280(transcript)|ensembl:ENSG00000162078(gene)|refseq:NP_660295.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0ymcb/0tSgZXhYQ6xHNIYrx9F3g9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O43399 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-782604|uniprotkb:Q5U0E0|uniprotkb:Q5JWU6|uniprotkb:Q9H3Z6|intact:EBI-1043547|uniprotkb:O43398|uniprotkb:Q5JWU5|uniprotkb:Q5JWU8|uniprotkb:E1P5G7|uniprotkb:B4DPJ6|ensembl:ENSP00000343547 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tpd54_human(display_long)|uniprotkb:Tumor protein D52-like 2(gene name synonym)|uniprotkb:TPD52L2(gene name)|psi-mi:TPD52L2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001230821.1|refseq:NP_003279.2|refseq:NP_955393.1|refseq:NP_955395.1|refseq:NP_955394.1|refseq:NP_955392.1|ensembl:ENSG00000101150(gene)|ensembl:ENST00000346249(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|interpro:IPR012341(Six-hairpin glycosidase)|mint:O43399 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:asqRlZnmqIzXCJ5TAHjxKcj046g9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IXS8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-8787606|uniprotkb:B2RCG7|uniprotkb:Q4ZG87|uniprotkb:Q53TX6|ensembl:ENSP00000393667 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:f126b_human(display_long)|uniprotkb:FAM126B(gene name)|psi-mi:FAM126B(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_776183.1|refseq:NP_001308547.1|refseq:NP_001308548.1|refseq:NP_001308550.1|refseq:NP_001308551.1|refseq:NP_001308556.1|refseq:XP_016859370.1|ensembl:ENSG00000155744(gene)|ensembl:ENST00000418596(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR018619 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:I66/zTS0nPVPDIA5Gw+hIaSl49c9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P55327 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-782581|uniprotkb:E5RKB4|uniprotkb:Q13056|uniprotkb:Q6FGP3|uniprotkb:Q6FGS3|uniprotkb:Q86YZ2|uniprotkb:B7Z414|uniprotkb:Q53EK8|uniprotkb:Q9UCX8|uniprotkb:C9J502|uniprotkb:D0UFD1|uniprotkb:D0UFD2|uniprotkb:D0UFD3|uniprotkb:D0UFD4|uniprotkb:D0UFD5|ensembl:ENSP00000368391 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tpd52_human(display_long)|uniprotkb:Protein N8(gene name synonym)|uniprotkb:TPD52(gene name)|psi-mi:TPD52(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001020423.1|refseq:NP_001020424.1|refseq:NP_005070.1|refseq:NP_001274069.1|refseq:NP_001274071.1|refseq:NP_001274072.1|refseq:NP_001274073.1|ensembl:ENSG00000076554(gene)|ensembl:ENST00000379097(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0030183"(B cell differentiation)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046903"(secretion)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR007327(Tumor protein D52)|mint:P55327|reactome:R-HSA-432722 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XNaAsDz2/29CkMFhPBhSmQsnOj49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5HYK7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2563437|uniprotkb:Q8N5E7|uniprotkb:Q9UFC8|uniprotkb:Q86XB3|uniprotkb:Q08EK1|uniprotkb:B7Z296|uniprotkb:Q5U3B8|uniprotkb:Q32N10|intact:EBI-28974104|ensembl:ENSP00000302913|ensembl:ENSP00000386848 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sh319_human(display_long)|uniprotkb:ADAM-binding protein Eve-1(gene name synonym)|uniprotkb:EEN-binding protein(gene name synonym)|uniprotkb:SH3D19(gene name)|psi-mi:SH3D19(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001009555.3|refseq:NP_001122395.1|refseq:NP_001122396.1|refseq:NP_001230278.1|ensembl:ENSP00000302913|ensembl:ENSP00000386848|ensembl:ENST00000409598|ensembl:ENSP00000387030|ensembl:ENST00000427414|ensembl:ENSP00000415694|ensembl:ENST00000514152|ensembl:ENSP00000423449|refseq:XP_011529948.1|refseq:XP_011529951.1|ensembl:ENSG00000109686(gene)|ensembl:ENST00000304527(transcript)|ensembl:ENST00000409252(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0022604"(regulation of cell morphogenesis)|go:"GO:0051044"(positive regulation of membrane protein ectodomain proteolysis)|go:"GO:0070064"(proline-rich region binding)|interpro:IPR001452(Src homology-3)|interpro:IPR035834|interpro:IPR035835|interpro:IPR036028|reactome:R-HSA-432722|refseq:XP_005262824.1|refseq:XP_016863268.1|refseq:XP_016863270.1|refseq:XP_016863271.1|refseq:XP_016863272.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:FHHjKjFAjdTiMJVEUVD9geriCn09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P78344 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-296519|uniprotkb:O60877|uniprotkb:P78404|uniprotkb:Q0VH00|uniprotkb:Q53EU1|uniprotkb:Q58EZ2|uniprotkb:Q8NI71|uniprotkb:Q96C16|ensembl:ENSP00000340281|ensembl:ENSP00000433371|ensembl:ENSP00000433664|uniprotkb:Q0VH01|uniprotkb:Q2NKW9|uniprotkb:Q49A79 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:if4g2_human(display_long)|uniprotkb:EIF4G2(gene name)|psi-mi:EIF4G2(display_short)|uniprotkb:DAP5(gene name synonym)|uniprotkb:OK/SW-cl.75(orf name)|uniprotkb:p97(gene name synonym)|uniprotkb:Death-associated protein 5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000110321(gene)|ensembl:ENST00000339995(transcript)|ensembl:ENST00000525681(transcript)|ensembl:ENST00000526148(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0007507"(heart development)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008219"(cell death)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0016020"(membrane)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030424"(axon)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0060999"(positive regulation of dendritic spine development)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|mint:P78344|rcsb pdb:3D3M|rcsb pdb:3L6A|rcsb pdb:4IUL|reactome:R-HSA-1169408|refseq:NP_001036024.3|refseq:NP_001166176.1|refseq:NP_001409.3|dip:DIP-31366N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:UIE1Um0s2KJ9hpaa9X6kfZ8enPc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15464 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4402156|uniprotkb:B9EGM0|uniprotkb:D3DRQ5|uniprotkb:Q504U5|uniprotkb:Q5VUM8|ensembl:ENSP00000366936 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:shb_human(display_long)|uniprotkb:SHB(gene name)|psi-mi:SHB(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003019.2|ensembl:ENSG00000107338(gene)|ensembl:ENST00000377707(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0007165"(signal transduction)|go:"GO:0030154"(cell differentiation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|interpro:IPR000980(SH2 motif)|interpro:IPR035040|interpro:IPR035045|interpro:IPR036860|mint:Q15464|reactome:R-HSA-4420097 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:DD+KZlDzdHYok9if0pI0b4yKcf49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P50402 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-489887|uniprotkb:Q6FI02|ensembl:ENSP00000358857|ensembl:ENSP00000507533 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:emd_human(display_long)|uniprotkb:EDMD(gene name synonym)|uniprotkb:STA(gene name synonym)|uniprotkb:EMD(gene name)|psi-mi:EMD(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000108.1|ensembl:ENSP00000358857|ensembl:ENSP00000507533|ensembl:ENSG00000102119(gene)|ensembl:ENST00000369842(transcript)|ensembl:ENST00000683627(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005637"(nuclear inner membrane)|go:"GO:0005640"(nuclear outer membrane)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0035914"(skeletal muscle cell differentiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0048147"(negative regulation of fibroblast proliferation)|go:"GO:0048487"(beta-tubulin binding)|go:"GO:0060828"(regulation of canonical Wnt signaling pathway)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071763"(nuclear membrane organization)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|interpro:IPR011015(LEM-like fold)|interpro:IPR034989|interpro:IPR035004|mint:P50402|rcsb pdb:1JEI|rcsb pdb:2ODC|rcsb pdb:2ODG|rcsb pdb:6GHD|rcsb pdb:6RPR|rcsb pdb:7NDY|reactome:R-HSA-2980766|reactome:R-HSA-2995383|reactome:R-HSA-4419969|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423|reactome:R-HSA-9609523|interpro:IPR003887(Lamino-associated polypeptide 2/emerin)|dip:DIP-34638N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:hqH2sFjAGwjIGtGX/rjVVFgaYsE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q99961 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-697911|uniprotkb:Q99668|uniprotkb:B4DRA1|uniprotkb:E7EVZ4|uniprotkb:M0QZV5|ensembl:ENSP00000269886 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sh3g1_human(display_long)|uniprotkb:Endophilin-2(gene name synonym)|uniprotkb:SH3 domain-containing GRB2-like protein 1(gene name synonym)|uniprotkb:SH3 domain protein 2B(gene name synonym)|uniprotkb:Extra eleven-nineteen leukemia fusion gene protein(gene name synonym)|uniprotkb:EEN fusion partner of MLL(gene name synonym)|uniprotkb:SH3GL1(gene name)|psi-mi:SH3GL1(display_short)|uniprotkb:CNSA1(gene name synonym)|uniprotkb:SH3D2B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001186872.1|refseq:NP_003016.1|refseq:NP_001186873.1|dip:DIP-29452N|ensembl:ENSG00000141985(gene)|ensembl:ENST00000269886(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0007417"(central nervous system development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008289"(lipid binding)|go:"GO:0016191"(synaptic vesicle uncoating)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031697"(beta-1 adrenergic receptor binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098815"(modulation of excitatory postsynaptic potential)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:1900244"(positive regulation of synaptic vesicle endocytosis)|interpro:IPR001452(Src homology-3)|interpro:IPR004148(BAR)|interpro:IPR027267|interpro:IPR028501|interpro:IPR035824|interpro:IPR036028|mint:Q99961|reactome:R-HSA-182971|reactome:R-HSA-6807004|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8875360 - - crc64:6E5BE978BC955077 figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Qzz+R0MGXEpZ6G0xoPglUBKBIfk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15334 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-299979|ensembl:ENSP00000321537|ensembl:ENSP00000492144|uniprotkb:O00188|uniprotkb:Q58F11|uniprotkb:Q86UK6|uniprotkb:A7MBM7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:l2gl1_human(display_long)|uniprotkb:DLG4(gene name synonym)|uniprotkb:LLGL1(gene name)|psi-mi:LLGL1(display_short)|uniprotkb:Human homolog to the D-lgl gene protein(gene name synonym)|uniprotkb:Hugl-1(gene name synonym)|uniprotkb:HUGL(gene name synonym)|uniprotkb:HUGL1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000131899(gene)|ensembl:ENSG00000284137(gene)|ensembl:ENST00000316843(transcript)|ensembl:ENST00000640494(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007409"(axonogenesis)|go:"GO:0008593"(regulation of Notch signaling pathway)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030424"(axon)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032588"(trans-Golgi network membrane)|go:"GO:0032878"(regulation of establishment or maintenance of cell polarity)|go:"GO:0045159"(myosin II binding)|go:"GO:0050708"(regulation of protein secretion)|go:"GO:0051294"(establishment of spindle orientation)|go:"GO:0065003"(protein-containing complex assembly)|interpro:IPR000664("Lethal(2) giant larvae protein")|interpro:IPR001680(WD40 repeat)|interpro:IPR013577(Lethal giant larvae homologue 2)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|go:"GO:0000137"(Golgi cis cisterna)|mint:Q15334|refseq:NP_004131.3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:VqlrgKVnWmXyx1lvnpRe9hRQD0Q9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q01082 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351561|intact:EBI-1642531|uniprotkb:O60837|uniprotkb:Q16057|uniprotkb:Q53R99|uniprotkb:Q59ER3|uniprotkb:Q8IX99|uniprotkb:B2RP63|ensembl:ENSP00000349259 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sptb2_human(display_long)|uniprotkb:SPTBN1(gene name)|psi-mi:SPTBN1(display_short)|uniprotkb:SPTB2(gene name synonym)|uniprotkb:Spectrin, non-erythroid beta chain 1(gene name synonym)|uniprotkb:Beta-II spectrin(gene name synonym)|uniprotkb:Fodrin beta chain(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003119.2|refseq:NP_842565.2|ensembl:ENSG00000115306(gene)|ensembl:ENST00000356805(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007182"(common-partner SMAD protein phosphorylation)|go:"GO:0008091"(spectrin)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030673"(axolemma)|go:"GO:0031430"(M band)|go:"GO:0032437"(cuticular plate)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0060390"(regulation of SMAD protein signal transduction)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1903076"(regulation of protein localization to plasma membrane)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:Q01082|rcsb pdb:1AA2|rcsb pdb:1BKR|rcsb pdb:3EDV|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|reactome:R-HSA-9703465|reactome:R-HSA-373753|refseq:XP_005264574.1|refseq:XP_006712150.1|refseq:XP_016860268.1|refseq:XP_016860269.1|refseq:XP_016860270.1|dip:DIP-33182N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:rQJxsoEirg87umLjsEwHcQ0/blQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UK76 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-720411|uniprotkb:Q53FG7|uniprotkb:Q7Z2D2|uniprotkb:Q7Z2F0|uniprotkb:B2R6K3|ensembl:ENSP00000387059 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:jupi1_human(display_long)|uniprotkb:JPT1(gene name)|psi-mi:JPT1(display_short)|uniprotkb:ARM2(gene name synonym)|uniprotkb:Androgen-regulated protein 2(gene name synonym)|uniprotkb:HN1(gene name synonym)|uniprotkb:Hematological and neurological expressed 1 protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001002032.1|refseq:NP_001002033.1|refseq:NP_057269.1|refseq:NP_001275538.1|refseq:NP_001275539.1|refseq:NP_001275540.1|ensembl:ENSG00000189159(gene)|ensembl:ENST00000409753(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0031965"(nuclear membrane)|interpro:IPR033335 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ASGBsHVjL+f4JI3EqYH2cd6mtls9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P00338 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-372327|uniprotkb:Q53G53|uniprotkb:Q6IBM7|uniprotkb:Q6ZNV1|ensembl:ENSP00000368722|ensembl:ENSP00000395337|ensembl:ENSP00000445331|ensembl:ENSP00000499898|ensembl:ENSP00000499977|ensembl:ENSP00000500953|uniprotkb:Q9UDE8|uniprotkb:Q9UDE9|uniprotkb:D3DQY3|uniprotkb:B7Z5E3|uniprotkb:B4DKQ2|uniprotkb:F8W819 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ldha_human(display_long)|uniprotkb:LDHA(gene name)|psi-mi:LDHA(display_short)|uniprotkb:LDH muscle subunit(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-59(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 19 protein(gene name synonym)|uniprotkb:PIG19(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001158886.1|ensembl:ENSG00000134333(gene)|ensembl:ENSG00000288299(gene)|ensembl:ENST00000379412(transcript)|ensembl:ENST00000422447(transcript)|ensembl:ENST00000542179(transcript)|ensembl:ENST00000671981(transcript)|ensembl:ENST00000672405(transcript)|ensembl:ENST00000673204(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0004459"(L-lactate dehydrogenase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006089"(lactate metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0007584"(response to nutrient)|go:"GO:0009749"(response to glucose)|go:"GO:0016020"(membrane)|go:"GO:0019674"(NAD metabolic process)|go:"GO:0019900"(kinase binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0042493"|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0042802"(identical protein binding)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043627"(response to estrogen)|go:"GO:0045296"(cadherin binding)|go:"GO:0048569"(post-embryonic animal organ development)|go:"GO:0051287"(NAD binding)|go:"GO:0051591"(response to cAMP)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001236(Lactate/malate dehydrogenase)|interpro:IPR001557(L-lactate/malate dehydrogenase)|interpro:IPR011304(L-lactate dehydrogenase)|interpro:IPR015955(Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal)|interpro:IPR018177|interpro:IPR022383|interpro:IPR036291|rcsb pdb:1I10|mint:P00338|rcsb pdb:4AJP|rcsb pdb:4JNK|rcsb pdb:4L4R|rcsb pdb:4L4S|rcsb pdb:4M49|rcsb pdb:4OJN|rcsb pdb:4OKN|rcsb pdb:4QO7|rcsb pdb:4QO8|rcsb pdb:4QSM|rcsb pdb:4QT0|rcsb pdb:4R68|rcsb pdb:4R69|rcsb pdb:4RLS|rcsb pdb:4ZVV|rcsb pdb:5IXS|rcsb pdb:5IXY|rcsb pdb:5W8H|rcsb pdb:5W8I|rcsb pdb:5W8J|rcsb pdb:5W8K|rcsb pdb:5W8L|rcsb pdb:5ZJD|rcsb pdb:5ZJE|rcsb pdb:5ZJF|rcsb pdb:6BAD|rcsb pdb:6BAG|rcsb pdb:6BAX|rcsb pdb:6BAZ|rcsb pdb:6BB0|rcsb pdb:6BB1|rcsb pdb:6BB2|rcsb pdb:6BB3|rcsb pdb:6MV8|rcsb pdb:6MVA|rcsb pdb:6Q0D|rcsb pdb:6SBU|rcsb pdb:6SBV|rcsb pdb:6ZZR|reactome:R-HSA-70268|rcsb pdb:6Q13|refseq:NP_001158887.1|refseq:NP_005557.1|refseq:NP_001128711.1|refseq:NP_001158888.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Zpq2lAJLPG+q2bMEru3cq7B5gCk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P31947 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-476295|uniprotkb:Q6FH30|uniprotkb:Q6FH51|uniprotkb:Q96DH0|ensembl:ENSP00000340989|intact:EBI-28970316 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:1433s_human(display_long)|uniprotkb:Stratifin(gene name synonym)|uniprotkb:Epithelial cell marker protein 1(gene name synonym)|uniprotkb:HME1(gene name synonym)|uniprotkb:SFN(gene name)|psi-mi:SFN(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000340989|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031424"(keratinization)|ensembl:ENSG00000175793(gene)|go:"GO:0042802"(identical protein binding)|go:"GO:0043154"(negative regulation of cysteine-type endopeptidase activity involved in apoptotic process)|ensembl:ENST00000339276(transcript)|go:"GO:0000079"(regulation of cyclin-dependent protein serine/threonine kinase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0001836"(release of cytochrome c from mitochondria)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0046827"(positive regulation of protein export from nucleus)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000308(14-3-3 protein)|go:"GO:0003334"(keratinocyte development)|interpro:IPR023409|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0007165"(signal transduction)|go:"GO:0008426"(protein kinase C inhibitor activity)|interpro:IPR023410|go:"GO:0008630"(intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:0010482"(regulation of epidermal cell division)|interpro:IPR036815|interpro:IPR037435|mint:P31947|rcsb pdb:1YWT|rcsb pdb:3IQJ|rcsb pdb:3IQU|rcsb pdb:3IQV|rcsb pdb:3LW1|rcsb pdb:3MHR|rcsb pdb:3O8I|rcsb pdb:3P1N|rcsb pdb:3P1O|rcsb pdb:3P1P|rcsb pdb:3P1Q|rcsb pdb:3P1R|rcsb pdb:3P1S|rcsb pdb:3SMK|rcsb pdb:3SML|rcsb pdb:3SMM|rcsb pdb:3SMN|rcsb pdb:3SMO|rcsb pdb:3SP5|rcsb pdb:3SPR|rcsb pdb:3T0L|rcsb pdb:3T0M|rcsb pdb:3U9X|rcsb pdb:3UX0|rcsb pdb:4DAT|rcsb pdb:4DAU|rcsb pdb:4DHM|rcsb pdb:4DHN|rcsb pdb:4DHO|rcsb pdb:4DHP|rcsb pdb:4DHQ|rcsb pdb:4DHR|rcsb pdb:4DHS|rcsb pdb:4DHT|rcsb pdb:4DHU|rcsb pdb:4FL5|rcsb pdb:4FR3|rcsb pdb:4IEA|rcsb pdb:4JC3|rcsb pdb:4JDD|rcsb pdb:4QLI|rcsb pdb:4Y32|rcsb pdb:4Y3B|rcsb pdb:4Y5I|rcsb pdb:5BTV|rcsb pdb:5HF3|rcsb pdb:1YZ5|rcsb pdb:5LTW|rcsb pdb:5LU1|rcsb pdb:5LU2|rcsb pdb:5MHC|rcsb pdb:5MOC|rcsb pdb:5MXO|rcsb pdb:7O34|rcsb pdb:7O3A|rcsb pdb:7O3F|rcsb pdb:7O3P|rcsb pdb:7O3Q|rcsb pdb:7NZV|rcsb pdb:7O3R|rcsb pdb:7O3S|rcsb pdb:7O57|rcsb pdb:7O59|rcsb pdb:7O5A|rcsb pdb:7O5C|rcsb pdb:7O5D|rcsb pdb:7O5F|rcsb pdb:7O5G|rcsb pdb:7O5O|rcsb pdb:7O5P|rcsb pdb:7O5S|rcsb pdb:7O5U|rcsb pdb:7O5X|rcsb pdb:7O6F|rcsb pdb:7O6G|rcsb pdb:7O6I|rcsb pdb:7O6J|rcsb pdb:7O6K|rcsb pdb:7O6M|rcsb pdb:7O6O|reactome:R-HSA-111447|reactome:R-HSA-1445148|reactome:R-HSA-5625740|reactome:R-HSA-5628897|rcsb pdb:6GHP|rcsb pdb:6HHP|rcsb pdb:6HKB|rcsb pdb:6HKF|rcsb pdb:6HMT|rcsb pdb:6G8Q|rcsb pdb:6HMU|rcsb pdb:6HN2|rcsb pdb:6NV2|rcsb pdb:6QDR|rcsb pdb:6QDS|rcsb pdb:6QDT|rcsb pdb:6QDU|rcsb pdb:6QHL|rcsb pdb:6QHM|rcsb pdb:6QIU|rcsb pdb:6QZR|rcsb pdb:6QZS|rcsb pdb:6R5L|rcsb pdb:6RHC|rcsb pdb:6RJL|rcsb pdb:6RJQ|rcsb pdb:6RJZ|rcsb pdb:6RK8|rcsb pdb:6RKI|rcsb pdb:6RKK|rcsb pdb:6RKM|rcsb pdb:6RL3|rcsb pdb:6RL4|rcsb pdb:6RL6|rcsb pdb:6RM5|rcsb pdb:6RM7|rcsb pdb:6RP6|rcsb pdb:6RWH|rcsb pdb:6RWI|rcsb pdb:5MYC|rcsb pdb:5N5R|rcsb pdb:5N5T|rcsb pdb:5N5W|rcsb pdb:5N75|rcsb pdb:5OEG|rcsb pdb:5OEH|rcsb pdb:5OK9|rcsb pdb:5OKF|rcsb pdb:5OM0|rcsb pdb:5OMA|rcsb pdb:6FAU|rcsb pdb:6FAV|rcsb pdb:6FAW|rcsb pdb:6FBB|rcsb pdb:6FBW|rcsb pdb:6FBY|rcsb pdb:6FCP|rcsb pdb:6FI4|rcsb pdb:6FI5|rcsb pdb:6G6X|rcsb pdb:6G8I|rcsb pdb:5MY9|rcsb pdb:6G8J|rcsb pdb:6G8K|rcsb pdb:6G8L|rcsb pdb:6G8P|rcsb pdb:6RWS|rcsb pdb:6TJM|rcsb pdb:6TL3|rcsb pdb:6RWU|rcsb pdb:6TLF|rcsb pdb:6TLG|rcsb pdb:6TM7|rcsb pdb:6TWZ|rcsb pdb:6W0L|rcsb pdb:6XWD|rcsb pdb:6XXC|rcsb pdb:6XY5|rcsb pdb:6Y18|rcsb pdb:6Y1D|rcsb pdb:6Y1J|rcsb pdb:6RX2|rcsb pdb:6S39|rcsb pdb:6S3C|rcsb pdb:6S40|rcsb pdb:6Y3M|rcsb pdb:6Y3O|rcsb pdb:6Y3R|rcsb pdb:6Y3S|rcsb pdb:6Y3V|rcsb pdb:6Y3W|rcsb pdb:6Y40|rcsb pdb:6S9Q|rcsb pdb:6Y44|rcsb pdb:6SIN|rcsb pdb:6Y58|rcsb pdb:6SIO|rcsb pdb:6Y7T|rcsb pdb:6SIP|rcsb pdb:6Y8A|rcsb pdb:6Y8B|rcsb pdb:6Y8D|rcsb pdb:6SIQ|rcsb pdb:6Y8E|rcsb pdb:6YE9|rcsb pdb:6YIA|rcsb pdb:6SLV|rcsb pdb:6YIB|rcsb pdb:6YIC|rcsb pdb:6YLU|rcsb pdb:6YOW|rcsb pdb:6YOX|rcsb pdb:6YOY|rcsb pdb:6YP2|rcsb pdb:6YP3|rcsb pdb:6YP8|rcsb pdb:6SLW|rcsb pdb:6SLX|rcsb pdb:6T5F|rcsb pdb:6T5H|rcsb pdb:6T80|rcsb pdb:6TCH|rcsb pdb:6YPL|rcsb pdb:6YPY|rcsb pdb:6YQ2|rcsb pdb:6ZCJ|rcsb pdb:7AEW|rcsb pdb:7AOG|rcsb pdb:7AXN|rcsb pdb:7AYF|rcsb pdb:7AZ1|rcsb pdb:7AZ2|rcsb pdb:7BDP|rcsb pdb:7BDT|rcsb pdb:7BDY|rcsb pdb:7BFW|rcsb pdb:7BG3|rcsb pdb:7BGQ|rcsb pdb:7BGR|rcsb pdb:7BGV|rcsb pdb:7BGW|rcsb pdb:7BI3|rcsb pdb:7BIQ|rcsb pdb:7BIY|rcsb pdb:7BJF|rcsb pdb:7BJL|rcsb pdb:7BJW|rcsb pdb:7BKH|rcsb pdb:7NFW|rcsb pdb:7NIF|rcsb pdb:7NIG|rcsb pdb:7NIX|rcsb pdb:7NJ6|rcsb pdb:7NJ8|rcsb pdb:7NJ9|rcsb pdb:7NJA|rcsb pdb:7NJB|rcsb pdb:7NK3|rcsb pdb:7NK5|rcsb pdb:7NLA|rcsb pdb:7NLE|rcsb pdb:7NM1|rcsb pdb:7NM3|rcsb pdb:7NM9|rcsb pdb:7NQP|rcsb pdb:7NR7|rcsb pdb:7NRK|rcsb pdb:7NRL|rcsb pdb:7NSV|rcsb pdb:7NV4|rcsb pdb:7NVI|rcsb pdb:7NWS|rcsb pdb:7NXS|rcsb pdb:7NXT|rcsb pdb:7NXW|rcsb pdb:7NXY|rcsb pdb:7NY4|rcsb pdb:7NYE|rcsb pdb:7NYF|rcsb pdb:7NYG|rcsb pdb:7NZ6|rcsb pdb:7NZG|rcsb pdb:7NZK|reactome:R-HSA-6804114|reactome:R-HSA-75035|reactome:R-HSA-9614399|refseq:NP_006133.1|dip:DIP-29861N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:HI+I1sXZRxVaRy9nzl3O0HmaSSE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NAX2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11997992|ensembl:ENSP00000319179|uniprotkb:Q5QP32|uniprotkb:Q8N0S7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:kdf1_human(display_long)|uniprotkb:KDF1(gene name)|psi-mi:KDF1(display_short)|uniprotkb:C1orf172(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000175707(gene)|ensembl:ENST00000320567(transcript)|go:"GO:0003334"(keratinocyte development)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005938"(cell cortex)|go:"GO:0010482"(regulation of epidermal cell division)|go:"GO:0010839"(negative regulation of keratinocyte proliferation)|go:"GO:0016331"(morphogenesis of embryonic epithelium)|go:"GO:0030054"(cell junction)|go:"GO:0031252"(cell leading edge)|go:"GO:0045606"(positive regulation of epidermal cell differentiation)|go:"GO:0048589"(developmental growth)|go:"GO:0060887"(limb epidermis development)|go:"GO:0061436"(establishment of skin barrier)|go:"GO:0072686"(mitotic spindle)|go:"GO:2000647"(negative regulation of stem cell proliferation)|interpro:IPR028003|refseq:NP_689578.2|refseq:XP_005245792.1|refseq:XP_011538924.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:1HxeDX1B2DyqjvZKvubHOS/CnDc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6P996 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1049813|uniprotkb:Q4F6X7|uniprotkb:O00236|uniprotkb:Q6PID7|uniprotkb:Q86YF1|uniprotkb:Q8N4Q9|uniprotkb:Q8TBS5|intact:EBI-10982185|uniprotkb:B4DR55|uniprotkb:B4DSL3|uniprotkb:E7EMH5|uniprotkb:E7EPL4|uniprotkb:H3BNZ1|ensembl:ENSP00000379691|ensembl:ENSP00000484595 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pdxd1_human(display_long)|uniprotkb:PDXDC1(gene name)|psi-mi:PDXDC1(display_short)|uniprotkb:KIAA0251(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001272373.1|refseq:NP_001272374.1|refseq:NP_001272376.1|refseq:NP_001272377.1|refseq:NP_001272379.1|refseq:NP_055842.2|refseq:XP_006725291.1|refseq:XP_006726663.1|refseq:XP_006725288.1|refseq:XP_006726660.1|ensembl:ENSG00000179889(gene)|ensembl:ENSG00000275498(gene)|ensembl:ENST00000396410(transcript)|ensembl:ENST00000618389(transcript)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0008117"(sphinganine-1-phosphate aldolase activity)|go:"GO:0016831"(carboxy-lyase activity)|go:"GO:0019752"(carboxylic acid metabolic process)|go:"GO:0030149"(sphingolipid catabolic process)|go:"GO:0030170"(pyridoxal phosphate binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|interpro:IPR002129(Pyridoxal phosphate-dependent decarboxylase)|interpro:IPR015421(Pyridoxal phosphate-dependent transferase, major region, subdomain 1)|interpro:IPR015424(Pyridoxal phosphate-dependent transferase, major region)|mint:Q6P996 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:59DMMTVwe8bQCfqtUSZcV+nhEDQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O76041 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2880203|ensembl:ENSP00000366326|uniprotkb:B0YJ45|uniprotkb:Q2TBD0|uniprotkb:Q9UIC4|uniprotkb:B9EIM9|uniprotkb:E9PRX7|uniprotkb:Q5VZT2|uniprotkb:Q70I54 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nebl_human(display_long)|uniprotkb:NEBL(gene name)|psi-mi:NEBL(display_short)|uniprotkb:Actin-binding Z-disk protein(gene name synonym)|uniprotkb:LNEBL(gene name synonym)|uniprotkb:C10orf113(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000078114(gene)|ensembl:ENST00000377122(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008307"(structural constituent of muscle)|go:"GO:0030018"(Z disc)|go:"GO:0031005"(filamin binding)|go:"GO:0031674"(I band)|go:"GO:0051015"(actin filament binding)|go:"GO:0055001"(muscle cell development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071691"(cardiac muscle thin filament assembly)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035631|interpro:IPR036028|mint:O76041|rcsb pdb:4F14|refseq:NP_006384.1|refseq:NP_001166955.1|refseq:NP_998734.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6+3t3OOFerBzWUyX3qtfz4DhFdg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O00515 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2880585|ensembl:ENSP00000375829|uniprotkb:Q96GD8|uniprotkb:O95614 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lad1_human(display_long)|uniprotkb:LAD1(gene name)|psi-mi:LAD1(display_short)|uniprotkb:LAD(gene name synonym)|uniprotkb:Linear IgA disease antigen(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000391967(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005604"(basement membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017404(Ladinin 1)|mint:O00515|ensembl:ENSG00000159166(gene)|refseq:NP_005549.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:C58/NEfIlDj38lGEIsWtqBNuSis9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q00341 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1049478|uniprotkb:Q9UCY3|uniprotkb:Q53QU2|uniprotkb:B4DTQ2|uniprotkb:E7EM71|intact:EBI-28974616|ensembl:ENSP00000399139 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vigln_human(display_long)|uniprotkb:High density lipoprotein-binding protein(gene name synonym)|uniprotkb:HDLBP(gene name)|psi-mi:HDLBP(display_short)|uniprotkb:HBP(gene name synonym)|uniprotkb:VGL(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000399139|refseq:NP_005327.1|refseq:NP_976221.1|refseq:NP_001230829.1|refseq:XP_011509360.1|refseq:XP_011509362.1|refseq:XP_016859429.1|ensembl:ENSG00000115677(gene)|ensembl:ENST00000427183(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006869"(lipid transport)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0008289"(lipid binding)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0045296"(cadherin binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|rcsb pdb:1VIG|rcsb pdb:1VIH|rcsb pdb:2CTE|rcsb pdb:2CTF|rcsb pdb:2CTJ|rcsb pdb:2CTK|rcsb pdb:2CTL|rcsb pdb:2CTM|reactome:R-HSA-8964011|refseq:NP_001307894.1|refseq:NP_001307895.1|refseq:XP_005247059.2|refseq:XP_006712538.1|refseq:XP_005247060.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:4NqKFEjUn5Fi5Ws3tirpanGqYwg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q16181 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2009373|uniprotkb:Q52M76|uniprotkb:Q6NX50|ensembl:ENSP00000381992 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sept7_human(display_long)|uniprotkb:SEPTIN7(gene name)|psi-mi:SEPTIN7(display_short)|uniprotkb:CDC10(gene name synonym)|uniprotkb:CDC10 protein homolog(gene name synonym)|uniprotkb:SEPT7(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001779.3|dip:DIP-47093N|ensembl:ENSG00000122545(gene)|ensembl:ENST00000399034(transcript)|go:"GO:0000776"(kinetochore)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0007283"(spermatogenesis)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016476"(regulation of embryonic cell shape)|go:"GO:0030154"(cell differentiation)|go:"GO:0030496"(midbody)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0032154"(cleavage furrow)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060271"(cilium assembly)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097227"(sperm annulus)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR008115(Septin 7)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|rcsb pdb:2QAG|rcsb pdb:3T5D|rcsb pdb:3TW4|rcsb pdb:6N0B|rcsb pdb:6N12|rcsb pdb:6UQQ|reactome:R-HSA-5687128 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:CweIjGLXC7eubvKR7vkkihEkcHg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q03001 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-310758|uniprotkb:Q5TBT0|uniprotkb:Q8N1T8|uniprotkb:Q8N8J3|uniprotkb:Q8WXK9|uniprotkb:Q96AK9|uniprotkb:Q96DQ5|uniprotkb:B7Z3H1|uniprotkb:Q9UN10|uniprotkb:Q9H555|uniprotkb:Q5TBT2|uniprotkb:Q8WXK8|uniprotkb:O94833|uniprotkb:Q12825|uniprotkb:Q13266|uniprotkb:Q13267|uniprotkb:Q13775|uniprotkb:Q5TF23|uniprotkb:Q96J76|uniprotkb:Q96QT5|uniprotkb:Q9UGD7|uniprotkb:Q9UGD8|intact:EBI-350219|uniprotkb:E7ERU0|intact:EBI-350252|uniprotkb:Q5TF24|intact:EBI-310783 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dyst_human(display_long)|uniprotkb:DST(gene name)|psi-mi:DST(display_short)|uniprotkb:BPAG1(gene name synonym)|uniprotkb:DMH(gene name synonym)|uniprotkb:DT(gene name synonym)|uniprotkb:KIAA0728(gene name synonym)|uniprotkb:230 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Hemidesmosomal plaque protein(gene name synonym)|uniprotkb:Dystonia musculorum protein(gene name synonym)|uniprotkb:BP230(gene name synonym)|uniprotkb:BP240(gene name synonym)|uniprotkb:230/240 kDa bullous pemphigoid antigen(gene name synonym)|uniprotkb:Bullous pemphigoid antigen 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_016866713.1|refseq:NP_001714.1|refseq:NP_056363.2|mint:Q03001|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008090"(retrograde axonal transport)|go:"GO:0009611"(response to wounding)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030056"(hemidesmosome)|go:"GO:0030424"(axon)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0031581"(hemidesmosome assembly)|go:"GO:0031673"(H zone)|go:"GO:0035371"(microtubule plus-end)|go:"GO:0042060"(wound healing)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0048870"(cell motility)|go:"GO:0051010"(microtubule plus-end binding)|go:"GO:1904115"(axon cytoplasm)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035915|interpro:IPR036534|interpro:IPR036872|interpro:IPR041573|interpro:IPR041615|interpro:IPR043197|rcsb pdb:3GJO|reactome:R-HSA-2022090|reactome:R-HSA-446107|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR003108(Growth-arrest-specific protein 2)|interpro:IPR011992(EF-Hand type)|ensembl:ENST00000244364|ensembl:ENSP00000244364|ensembl:ENSG00000151914|ensembl:ENST00000370765|ensembl:ENSP00000359801|ensembl:ENST00000370788|ensembl:ENSP00000359824|ensembl:ENST00000439203|ensembl:ENSP00000404924|refseq:NP_001138241.1|refseq:NP_001138242.1|refseq:NP_899236.1|dip:DIP-33131N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:5jynCc9AQYiyXSw6P4v3wzlVNU49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q52LW3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-747415|uniprotkb:Q8TBI6|uniprotkb:O15463|uniprotkb:Q59H86|uniprotkb:Q5VYZ0|uniprotkb:Q6NVX2|ensembl:ENSP00000260526 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rhg29_human(display_long)|uniprotkb:PTPL1-associated RhoGAP protein 1(gene name synonym)|uniprotkb:ARHGAP29(gene name)|psi-mi:ARHGAP29(display_short)|uniprotkb:PARG1(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 29(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004806.3|refseq:XP_011540741.1|refseq:NP_001315593.1|ensembl:ENSG00000137962(gene)|ensembl:ENST00000260526(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR000198(RhoGAP)|interpro:IPR002219(Protein kinase C, phorbol ester/diacylglycerol binding)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR027267|interpro:IPR031160|mint:Q52LW3|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:FbQVb39L1+vnsmEJforpsvLhJIY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UHB6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351479|uniprotkb:Q2TAN7|uniprotkb:Q9BVF2|uniprotkb:Q9H8J1|uniprotkb:Q9HBN5|uniprotkb:Q9NX96|uniprotkb:Q9NXC3|uniprotkb:Q9NXU6|uniprotkb:Q9P0H8|uniprotkb:Q9UHB5|uniprotkb:B2RB09|ensembl:ENSP00000340184|uniprotkb:Q59FE8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lima1_human(display_long)|uniprotkb:PP624(orf name)|uniprotkb:LIMA1(gene name)|psi-mi:LIMA1(display_short)|uniprotkb:SREBP3(gene name synonym)|uniprotkb:Epithelial protein lost in neoplasm(gene name synonym)|uniprotkb:EPLIN(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001107018.1|refseq:NP_001107019.1|refseq:NP_057441.1|refseq:XP_011536757.1|ensembl:ENSG00000050405(gene)|ensembl:ENST00000341247(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001726"(ruffle)|go:"GO:0003785"(actin monomer binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016477"(cell migration)|go:"GO:0030299"(intestinal cholesterol absorption)|go:"GO:0030835"(negative regulation of actin filament depolymerization)|go:"GO:0031526"(brush border membrane)|go:"GO:0031529"(ruffle organization)|go:"GO:0032154"(cleavage furrow)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028740|mint:Q9UHB6|rcsb pdb:2D8Y|refseq:NP_001230704.1|refseq:XP_016874919.1|dip:DIP-29633N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:sHqhe21LVzLJXgDMH6IcWukKNHE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P49023 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-702209|uniprotkb:O14970|uniprotkb:O14971|uniprotkb:O60360|uniprotkb:B2RAI3|uniprotkb:Q5HYA4|uniprotkb:B7ZMB4|ensembl:ENSP00000228307 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:paxi_human(display_long)|uniprotkb:PXN(gene name)|psi-mi:PXN(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001074324.1|refseq:NP_002850.2|refseq:NP_079433.3|refseq:NP_001230685.1|refseq:XP_016875232.1|dip:DIP-33851N|ensembl:ENSG00000089159(gene)|ensembl:ENST00000228307(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0005829"(cytosol)|go:"GO:0005875"(microtubule associated complex)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007172"(signal complex assembly)|go:"GO:0007179"(transforming growth factor beta receptor signaling pathway)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0017166"(vinculin binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0038191"(neuropilin binding)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0060396"(growth hormone receptor signaling pathway)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001904(Paxillin)|mint:P49023|rcsb pdb:1KKY|rcsb pdb:1KL0|rcsb pdb:1OW6|rcsb pdb:1OW7|rcsb pdb:1OW8|rcsb pdb:2K2R|rcsb pdb:2O9V|rcsb pdb:2VZD|rcsb pdb:2VZG|rcsb pdb:2VZI|rcsb pdb:3GM1|rcsb pdb:3PY7|rcsb pdb:3RQE|rcsb pdb:3RQF|rcsb pdb:3RQG|rcsb pdb:3U3F|rcsb pdb:4EDN|rcsb pdb:4R32|rcsb pdb:4XGZ|rcsb pdb:4XH2|rcsb pdb:5UWH|rcsb pdb:6IUI|rcsb pdb:6PW8|rcsb pdb:6U4M|rcsb pdb:6U4N|reactome:R-HSA-180292|reactome:R-HSA-4420097|reactome:R-HSA-445355|reactome:R-HSA-446343|reactome:R-HSA-446388|reactome:R-HSA-8849471 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:H8osAQRrVydLfDL97uSSA6Mf6ME9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15654 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-742327|uniprotkb:O15170|uniprotkb:O15275|uniprotkb:Q9BTB2|uniprotkb:Q9BUE5|uniprotkb:Q9BXP3|uniprotkb:Q9UNT4|uniprotkb:A4D2E7|ensembl:ENSP00000200457|uniprotkb:F2ZC07|uniprotkb:F2ZC08 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:trip6_human(display_long)|uniprotkb:TRIP6(gene name)|psi-mi:TRIP6(display_short)|uniprotkb:OIP1(gene name synonym)|uniprotkb:Opa-interacting protein 1(gene name synonym)|uniprotkb:Zyxin-related protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003293.2|ensembl:ENSP00000200457|ensembl:ENST00000417475|ensembl:ENSP00000413817|ensembl:ENST00000437505|ensembl:ENSP00000410736|ensembl:ENST00000619988|ensembl:ENSP00000479865|ensembl:ENSG00000087077(gene)|ensembl:ENST00000200457(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003723"(RNA binding)|go:"GO:0005149"(interleukin-1 receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0019900"(kinase binding)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043009"(chordate embryonic development)|go:"GO:0046872"(metal ion binding)|go:"GO:0046966"(thyroid hormone receptor binding)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|interpro:IPR001781(Zinc finger, LIM-type)|mint:Q15654|rcsb pdb:1X61|rcsb pdb:2DLO|dip:DIP-34466N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9Okf3b6sMMwX5awAx991GN9iSsQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35611 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2809187|uniprotkb:A2A3N8|intact:EBI-28966889|ensembl:ENSP00000381197|uniprotkb:Q16156|uniprotkb:Q14729|uniprotkb:A2A3P0|uniprotkb:Q13734|uniprotkb:Q9UJB6|uniprotkb:D3DVR3|uniprotkb:D3DVR4|uniprotkb:D3DVR5|uniprotkb:Q86XM2|uniprotkb:B4DI79 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:adda_human(display_long)|uniprotkb:ADD1(gene name)|psi-mi:ADD1(display_short)|uniprotkb:ADDA(gene name synonym)|uniprotkb:Erythrocyte adducin subunit alpha(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000264758|ensembl:ENSP00000264758|ensembl:ENST00000355842|ensembl:ENSP00000348100|ensembl:ENST00000398123|ensembl:ENSP00000381191|ensembl:ENST00000398125|ensembl:ENSP00000381193|ensembl:ENSP00000381197|ensembl:ENST00000651918|ensembl:ENSP00000498269|ensembl:ENSG00000087274(gene)|ensembl:ENST00000398129(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008290"(F-actin capping protein complex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030507"(spectrin binding)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|go:"GO:1903393"(positive regulation of adherens junction organization)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR027766|interpro:IPR036409|reactome:R-HSA-264870|reactome:R-HSA-381038|reactome:R-HSA-5223345|go:"GO:0045296"(cadherin binding)|refseq:NP_001273574.1|refseq:XP_005247994.1|refseq:NP_001110.2|refseq:NP_054908.2|refseq:NP_054909.2|refseq:XP_016863193.1|refseq:XP_016863195.1|refseq:XP_016863196.1|refseq:XP_016863197.1|refseq:XP_016863198.1|refseq:XP_016863199.1|refseq:NP_789771.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:aXiCTFAzsmSxxV4OAr22SDyjAxI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H6S3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3940939|uniprotkb:Q53GM8|uniprotkb:Q9H6K9|uniprotkb:B3KSX1|uniprotkb:Q96K06|uniprotkb:Q8WYW7|ensembl:ENSP00000320828|ensembl:ENSP00000435585|ensembl:ENSP00000436035|uniprotkb:B7ZKL3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:es8l2_human(display_long)|uniprotkb:EPS8L2(gene name)|psi-mi:EPS8L2(display_short)|uniprotkb:EPS8R2(gene name synonym)|uniprotkb:Epidermal growth factor receptor pathway substrate 8-related protein 2(gene name synonym)|uniprotkb:PP13181(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000177106(gene)|ensembl:ENST00000318562(transcript)|ensembl:ENST00000530636(transcript)|ensembl:ENST00000533256(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0007605"(sensory perception of sound)|go:"GO:0031982"(vesicle)|go:"GO:0032421"(stereocilium bundle)|go:"GO:0032426"(stereocilium tip)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0045296"(cadherin binding)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1900029"(positive regulation of ruffle assembly)|interpro:IPR001452(Src homology-3)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR013625(Tensin phosphotyrosine-binding domain)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR033928|interpro:IPR035462|interpro:IPR036028|interpro:IPR039801|interpro:IPR041418|mint:Q9H6S3|rcsb pdb:1WWU|rcsb pdb:1WXB|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_073609.2|refseq:XP_016873619.1|refseq:XP_016873620.1|refseq:XP_016873621.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fm46f0tF2y2QGPLD7dk77JUHMXA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P28072 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-359288|uniprotkb:Q96J55|ensembl:ENSP00000270586 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:psb6_human(display_long)|uniprotkb:PSMB6(gene name)|psi-mi:PSMB6(display_short)|uniprotkb:LMPY(gene name synonym)|uniprotkb:Proteasome delta chain(gene name synonym)|uniprotkb:Macropain delta chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex delta chain(gene name synonym)|uniprotkb:Proteasome subunit Y(gene name synonym)|uniprotkb:Y(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002789.1|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR035140|mint:P28072|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|go:"GO:0005737"(cytoplasm)|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5610785|reactome:R-HSA-5632684|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|ensembl:ENSG00000142507(gene)|ensembl:ENST00000270586(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|dip:DIP-33847N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:4LRxYA6/tM2hsc96iP29c5J7ew49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q93052 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-718388|uniprotkb:D3DNV6|uniprotkb:Q8NFX5|uniprotkb:A1L4L6|ensembl:ENSP00000478901|ensembl:ENSP00000491657 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lpp_human(display_long)|uniprotkb:LIM domain-containing preferred translocation partner in lipoma(gene name synonym)|uniprotkb:LPP(gene name)|psi-mi:LPP(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001161143.1|refseq:NP_005569.1|refseq:XP_011511122.1|refseq:XP_011511129.1|refseq:XP_011511130.1|refseq:XP_011511133.1|refseq:XP_011511135.1|refseq:XP_016861866.1|refseq:XP_016861867.1|refseq:XP_016861868.1|refseq:XP_016861869.1|refseq:XP_011511136.1|refseq:XP_005247503.1|refseq:XP_005247507.1|refseq:XP_005247508.1|refseq:XP_005247510.1|ensembl:ENSG00000145012(gene)|ensembl:ENST00000617246(transcript)|ensembl:ENST00000640853(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0046872"(metal ion binding)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR028771|mint:Q93052 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:1gZYhWdxZ0ogIkf0xrCOKZiAiyE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WU20 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1104330|uniprotkb:O43558|uniprotkb:Q7LDQ6|uniprotkb:B0LPF2|uniprotkb:B2R684|ensembl:ENSP00000381083|ensembl:ENSP00000447241|ensembl:ENSP00000450048 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:frs2_human(display_long)|uniprotkb:FRS2(gene name)|psi-mi:FRS2(display_short)|uniprotkb:Suc1-associated neurotrophic factor target 1(gene name synonym)|uniprotkb:FGFR-signaling adaptor SNT(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000166225(gene)|ensembl:ENST00000397997(transcript)|ensembl:ENST00000549921(transcript)|ensembl:ENST00000550389(transcript)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001759"(organ induction)|go:"GO:0003281"(ventricular septum development)|go:"GO:0005068"(transmembrane receptor protein tyrosine kinase adaptor activity)|go:"GO:0005104"(fibroblast growth factor receptor binding)|go:"GO:0005168"(neurotrophin TRKA receptor binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007185"(transmembrane receptor protein tyrosine phosphatase signaling pathway)|go:"GO:0007405"(neuroblast proliferation)|go:"GO:0007186"(G protein-coupled receptor signaling pathway)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008595"(anterior/posterior axis specification, embryo)|go:"GO:0012505"(endomembrane system)|go:"GO:0016020"(membrane)|go:"GO:0019211"(phosphatase activator activity)|go:"GO:0030900"(forebrain development)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0046619"(lens placode formation involved in camera-type eye formation)|go:"GO:0050678"(regulation of epithelial cell proliferation)|go:"GO:0060527"(prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis)|go:"GO:0070307"(lens fiber cell development)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:2000726"(negative regulation of cardiac muscle cell differentiation)|interpro:IPR002404(Insulin receptor substrate-1, PTB)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR038742|mint:Q8WU20|rcsb pdb:1XR0|rcsb pdb:2MFQ|reactome:R-HSA-109704|reactome:R-HSA-1257604|reactome:R-HSA-170968|reactome:R-HSA-2219530|reactome:R-HSA-5654689|reactome:R-HSA-5654693|reactome:R-HSA-5654695|reactome:R-HSA-5654700|reactome:R-HSA-5654706|reactome:R-HSA-5654710|reactome:R-HSA-5654712|reactome:R-HSA-5654720|reactome:R-HSA-5654726|reactome:R-HSA-5654727|reactome:R-HSA-5654732|reactome:R-HSA-5654733|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-5673001|reactome:R-HSA-6811558|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-9028731|reactome:R-HSA-9696270|reactome:R-HSA-9696273|refseq:NP_001036020.1|refseq:NP_006645.3|refseq:NP_001265280.1|refseq:NP_001265282.1|refseq:NP_001265283.1|refseq:NP_001265284.1|refseq:NP_001265285.1|refseq:NP_001265286.1|refseq:XP_016874206.1|refseq:XP_016874207.1|refseq:XP_016874208.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7tSNEY7uVWJZtQ3l1zd1xhkaoUU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96MW1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-9247198|uniprotkb:C9JVK9|ensembl:ENSP00000323782 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ccd43_human(display_long)|uniprotkb:CCDC43(gene name)|psi-mi:CCDC43(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001092695.1|refseq:NP_653210.2|ensembl:ENSG00000180329(gene)|ensembl:ENST00000315286(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR037666 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:QBglG4w5dKBiI8SAnoWsqpiGgvI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y624 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-742600|uniprotkb:B7Z941|ensembl:ENSP00000357005 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:jam1_human(display_long)|uniprotkb:Junctional adhesion molecule 1(gene name synonym)|uniprotkb:Platelet adhesion molecule 1(gene name synonym)|uniprotkb:Platelet F11 receptor(gene name synonym)|uniprotkb:F11R(gene name)|psi-mi:F11R(display_short)|uniprotkb:JAM1(gene name synonym)|uniprotkb:JCAM(gene name synonym)|uniprotkb:UNQ264/PRO301(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_058642.1|ensembl:ENSG00000158769(gene)|ensembl:ENST00000368026(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001817"(regulation of cytokine production)|go:"GO:0005178"(integrin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0006954"(inflammatory response)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0045296"(cadherin binding)|go:"GO:0045777"(positive regulation of blood pressure)|go:"GO:0050892"(intestinal absorption)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070160"(tight junction)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1901731"(positive regulation of platelet aggregation)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903142"(positive regulation of establishment of endothelial barrier)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR003598(Immunoglobulin subtype 2)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR036179|interpro:IPR042456|mint:Q9Y624|rcsb pdb:1NBQ|rcsb pdb:3EOY|rcsb pdb:3TSZ|rcsb pdb:4ODB|reactome:R-HSA-202733|reactome:R-HSA-216083|reactome:R-HSA-2173791|reactome:R-HSA-420029|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0035025"(positive regulation of Rho protein signal transduction)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0035683"(memory T cell extravasation)|go:"GO:0036057"(slit diaphragm)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0009314"(response to radiation)|refseq:NP_001335020.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9TaktSbIwjn9jMYlv86aB44hwes9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13596 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2822329|uniprotkb:O60750|uniprotkb:A8K6T7|uniprotkb:A6NM19|uniprotkb:O60751|uniprotkb:H0Y2M5|uniprotkb:Q6ZRJ8|ensembl:ENSP00000453785 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snx1_human(display_long)|uniprotkb:SNX1(gene name)|psi-mi:SNX1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003090.2|refseq:NP_683758.1|refseq:NP_001229862.1|ensembl:ENSG00000028528(gene)|ensembl:ENST00000559844(transcript)|go:"GO:0005154"(epidermal growth factor receptor binding)|go:"GO:0005158"(insulin receptor binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0016020"(membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030904"(retromer complex)|go:"GO:0030905"(retromer, tubulation complex)|go:"GO:0031623"(receptor internalization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0072673"(lamellipodium morphogenesis)|go:"GO:1990459"(transferrin receptor binding)|go:"GO:1990460"(leptin receptor binding)|interpro:IPR001683(Phox-like)|interpro:IPR005329(Sorting nexin, N-terminal)|interpro:IPR015404(Vps5 C terminal like)|interpro:IPR027267|interpro:IPR028660|interpro:IPR034901|mint:Q13596|rcsb pdb:2I4K|rcsb pdb:4FZS|interpro:IPR036871|dip:DIP-398N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:nFyxCtQ9gHndLbuCjBiwhyWE5do9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14134 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-702370|uniprotkb:Q96AA9|uniprotkb:Q9BZY7|ensembl:ENSP00000343129 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tri29_human(display_long)|uniprotkb:Ataxia telangiectasia group D-associated protein(gene name synonym)|uniprotkb:TRIM29(gene name)|psi-mi:TRIM29(display_short)|uniprotkb:ATDC(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_036233.2|ensembl:ENSG00000137699(gene)|ensembl:ENST00000341846(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0002039"(p53 binding)|go:"GO:0005764"(lysosome)|go:"GO:0005912"(adherens junction)|go:"GO:0008270"(zinc ion binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045087"(innate immune response)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|interpro:IPR000315(Zinc finger, B-box)|rcsb pdb:2CSV|reactome:R-HSA-877300 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Sl9ZyD/8cbBpW722qTsDJ+YQqiE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y570 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1772895|uniprotkb:Q8WYG8|uniprotkb:Q9NVT5|uniprotkb:Q9UI18|uniprotkb:B3KMU6|uniprotkb:B5MEE7|uniprotkb:J3QT22|ensembl:ENSP00000329867 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ppme1_human(display_long)|uniprotkb:PPME1(gene name)|psi-mi:PPME1(display_short)|uniprotkb:PME1(gene name synonym)|uniprotkb:PP2593(orf name)|uniprotkb:PRO0750(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_057231.1|refseq:NP_001258522.1|ensembl:ENSG00000214517(gene)|ensembl:ENST00000328257(transcript)|go:"GO:0000086"(G2/M transition of mitotic cell cycle)|go:"GO:0004864"(protein phosphatase inhibitor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006482"(protein demethylation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051721"(protein phosphatase 2A binding)|go:"GO:0051722"(protein C-terminal methylesterase activity)|go:"GO:0051723"(protein methylesterase activity)|interpro:IPR000073(Alpha/beta hydrolase fold-1)|interpro:IPR016812(Protein phosphatase methylesterase, eukaryotic)|interpro:IPR029058|rcsb pdb:3C5V|rcsb pdb:3C5W|reactome:R-HSA-69273 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZOIwpvvy8nrnGzuNkEu7AZn0JuA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H4M9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-490691|uniprotkb:O14611|uniprotkb:Q2M3Q4|uniprotkb:Q9UNR3|ensembl:ENSP00000320516|ensembl:ENSP00000352354 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ehd1_human(display_long)|uniprotkb:Testilin(gene name synonym)|uniprotkb:CDABP0131(orf name)|uniprotkb:EHD1(gene name)|psi-mi:EHD1(display_short)|uniprotkb:PAST(gene name synonym)|uniprotkb:PAST1(gene name synonym)|uniprotkb:PAST homolog 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0048471"(perinuclear region of cytoplasm)|refseq:NP_006786.2|refseq:XP_011543041.1|refseq:NP_001269373.1|refseq:NP_001269374.1|ensembl:ENSG00000110047(gene)|ensembl:ENST00000320631(transcript)|ensembl:ENST00000359393(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005525"(GTP binding)|go:"GO:0005769"(early endosome)|go:"GO:0005811"(lipid droplet)|go:"GO:0005886"(plasma membrane)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006897"(endocytosis)|go:"GO:0010008"(endosome membrane)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0031095"(platelet dense tubular network membrane)|go:"GO:0031175"(neuron projection development)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051260"(protein homooligomerization)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061512"(protein localization to cilium)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:1901741"(positive regulation of myoblast fusion)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:2001137"(positive regulation of endocytic recycling)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|interpro:IPR022812|interpro:IPR027417|interpro:IPR029951|interpro:IPR030381|interpro:IPR031692|interpro:IPR040990|mint:Q9H4M9|rcsb pdb:2JQ6|rcsb pdb:2KFF|rcsb pdb:2KFG|rcsb pdb:2KFH|rcsb pdb:2KSP|reactome:R-HSA-983231 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:txUfRMtv6SbBqKKJ1DVM6K/pj2Y9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P62826 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-286642|uniprotkb:P17080|uniprotkb:P28746|uniprotkb:P28747|uniprotkb:Q6IPB2|uniprotkb:Q86V08|uniprotkb:Q8NI90|uniprotkb:Q9CZA2|uniprotkb:Q9CSP3|uniprotkb:Q9CWI7|uniprotkb:Q9UDJ5|uniprotkb:Q9UEU9|uniprotkb:A8K3Z8|ensembl:ENSP00000376176|ensembl:ENSP00000446215 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ran_human(display_long)|uniprotkb:GTPase Ran(gene name synonym)|uniprotkb:Ras-related nuclear protein(gene name synonym)|uniprotkb:Ras-like protein TC4(gene name synonym)|uniprotkb:Androgen receptor-associated protein 24(gene name synonym)|uniprotkb:RAN(gene name)|psi-mi:RAN(display_short)|uniprotkb:ARA24(gene name synonym)|uniprotkb:OK/SW-cl.81(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006316.1|refseq:NP_001287725.1|refseq:NP_001287726.1|dip:DIP-5929N|ensembl:ENSG00000132341(gene)|ensembl:ENST00000392369(transcript)|ensembl:ENST00000543796(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000055"(ribosomal large subunit export from nucleus)|go:"GO:0000056"(ribosomal small subunit export from nucleus)|go:"GO:0000070"(mitotic sister chromatid segregation)|go:"GO:0000278"(mitotic cell cycle)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005814"(centriole)|go:"GO:0005829"(cytosol)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006606"(protein import into nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0007052"(mitotic spindle organization)|go:"GO:0016020"(membrane)|go:"GO:0016032"(viral process)|go:"GO:0019003"(GDP binding)|go:"GO:0030496"(midbody)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042470"(melanosome)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0046039"(GTP metabolic process)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051301"(cell division)|go:"GO:0055037"(recycling endosome)|go:"GO:0061015"(snRNA import into nucleus)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902570"(protein localization to nucleolus)|interpro:IPR001806(Ras GTPase)|interpro:IPR002041(Ran GTPase)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:P62826|rcsb pdb:1I2M|rcsb pdb:1IBR|rcsb pdb:1K5D|rcsb pdb:1K5G|rcsb pdb:1QBK|rcsb pdb:1RRP|rcsb pdb:2MMC|rcsb pdb:2MMG|rcsb pdb:2N1B|rcsb pdb:3CH5|rcsb pdb:3EA5|rcsb pdb:3GJ0|rcsb pdb:3GJ3|rcsb pdb:3GJ4|rcsb pdb:3GJ5|rcsb pdb:3GJ6|rcsb pdb:3GJ7|rcsb pdb:3GJ8|rcsb pdb:3GJX|rcsb pdb:3NBY|rcsb pdb:3NBZ|rcsb pdb:3NC0|rcsb pdb:3NC1|rcsb pdb:3ZJY|rcsb pdb:4C0Q|rcsb pdb:4GMX|rcsb pdb:4GPT|rcsb pdb:4HAT|rcsb pdb:4HAU|rcsb pdb:4HAV|rcsb pdb:4HAW|rcsb pdb:4HAX|rcsb pdb:4HAY|rcsb pdb:4HAZ|rcsb pdb:4HB0|rcsb pdb:4HB2|rcsb pdb:4HB3|rcsb pdb:4HB4|rcsb pdb:4OL0|rcsb pdb:4WVF|rcsb pdb:5CIQ|rcsb pdb:5CIT|rcsb pdb:5CIW|rcsb pdb:5CJ2|rcsb pdb:5CLL|rcsb pdb:5CLQ|rcsb pdb:5DH9|rcsb pdb:5DHA|rcsb pdb:5DHF|rcsb pdb:5DI9|rcsb pdb:5DIF|rcsb pdb:5DIS|rcsb pdb:5DLQ|rcsb pdb:5FYQ|rcsb pdb:5JLJ|rcsb pdb:5UWH|rcsb pdb:5UWI|rcsb pdb:5UWJ|rcsb pdb:5UWO|rcsb pdb:5UWP|rcsb pdb:5UWQ|rcsb pdb:5UWR|rcsb pdb:5UWS|rcsb pdb:5UWT|rcsb pdb:5UWU|rcsb pdb:5UWW|rcsb pdb:5YRO|rcsb pdb:5YST|rcsb pdb:5YSU|rcsb pdb:5YTB|rcsb pdb:5ZPU|rcsb pdb:6A38|rcsb pdb:6A3A|rcsb pdb:6A3B|rcsb pdb:6A3C|rcsb pdb:6A3E|rcsb pdb:6CIT|rcsb pdb:6KFT|rcsb pdb:6LQ9|rcsb pdb:6M60|rcsb pdb:6M6X|rcsb pdb:6Q82|rcsb pdb:6Q84|rcsb pdb:6TVO|rcsb pdb:6X2M|rcsb pdb:6X2O|rcsb pdb:6X2P|rcsb pdb:6X2R|rcsb pdb:6X2S|rcsb pdb:6X2U|rcsb pdb:6X2V|rcsb pdb:6X2W|rcsb pdb:6X2X|rcsb pdb:6X2Y|rcsb pdb:6XJP|rcsb pdb:6XJR|rcsb pdb:6XJS|rcsb pdb:6XJT|rcsb pdb:6XJU|rcsb pdb:7B51|rcsb pdb:7CND|rcsb pdb:7L5E|reactome:R-HSA-165054|reactome:R-HSA-1655829|reactome:R-HSA-168333|reactome:R-HSA-180746|reactome:R-HSA-203927|reactome:R-HSA-5578749|reactome:R-HSA-6784531|reactome:R-HSA-9615933 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:trIUv5n3nI5d0rkfDTgw/6ubxMA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P23588 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-970310|ensembl:ENSP00000262056|uniprotkb:Q4G0E3|uniprotkb:Q53HQ2|uniprotkb:Q6GPH5|uniprotkb:Q6IB46|uniprotkb:Q8WYK5|uniprotkb:B4DS13 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:if4b_human(display_long)|uniprotkb:EIF4B(gene name)|psi-mi:EIF4B(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000063046(gene)|ensembl:ENST00000262056(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030425"(dendrite)|go:"GO:0033592"(RNA strand annealing activity)|go:"GO:0034057"(RNA strand-exchange activity)|go:"GO:0043024"(ribosomal small subunit binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0097010"(eukaryotic translation initiation factor 4F complex assembly)|go:"GO:0098794"(postsynapse)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR033107|interpro:IPR035979|mint:P23588|rcsb pdb:1WI8|rcsb pdb:2J76|rcsb pdb:6FEC|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|refseq:NP_001408.2|refseq:NP_001317583.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6QlRkSj6suC5apkUxdZhOq+OMBc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P43487 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1032909|uniprotkb:Q53EY3|ensembl:ENSP00000327583 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rang_human(display_long)|uniprotkb:RANBP1(gene name)|psi-mi:RANBP1(display_short)|uniprotkb:Ran-binding protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002873.1|ensembl:ENSG00000099901(gene)|ensembl:ENST00000331821(transcript)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005643"(nuclear pore)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046604"(positive regulation of mitotic centrosome separation)|go:"GO:0046907"(intracellular transport)|interpro:IPR000156(Ran Binding Protein 1)|interpro:IPR011993(Pleckstrin homology-type)|rcsb pdb:1K5D|rcsb pdb:1K5G|reactome:R-HSA-165054|refseq:NP_001265568.1|refseq:NP_001265569.1|dip:DIP-35058N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:OWndphaUCDSO3+MGhJqcuQo2Lk09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P50990 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-356507|uniprotkb:A6NN54|uniprotkb:Q4VBP8|uniprotkb:B4DEM7|uniprotkb:B4DQH4|ensembl:ENSP00000286788 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tcpq_human(display_long)|uniprotkb:CCT8(gene name)|psi-mi:CCT8(display_short)|uniprotkb:CCTQ(gene name synonym)|uniprotkb:KIAA0002(gene name synonym)|uniprotkb:CCT-theta(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-15(gene name synonym)|uniprotkb:C21orf112(gene name synonym)|uniprotkb:Chaperonin containing T-complex polypeptide 1 subunit 8(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001269836.1|refseq:NP_001269838.1|refseq:NP_006576.2|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0044297"(cell body)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050821"(protein stabilization)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901998"(toxin transport)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1904851"(positive regulation of establishment of protein localization to telomere)|go:"GO:1904871"(positive regulation of protein localization to Cajal body)|go:"GO:1904874"(positive regulation of telomerase RNA localization to Cajal body)|interpro:IPR002194(Chaperonin TCP-1, conserved site)|interpro:IPR002423(Chaperonin Cpn60/TCP-1)|interpro:IPR012721(T-complex protein 1, theta subunit)|interpro:IPR017998|interpro:IPR027409|interpro:IPR027410|interpro:IPR027413|mint:P50990|rcsb pdb:6NR8|rcsb pdb:6NR9|rcsb pdb:6NRA|rcsb pdb:6NRB|rcsb pdb:6NRC|rcsb pdb:6NRD|rcsb pdb:6QB8|rcsb pdb:7LUM|rcsb pdb:7LUP|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|reactome:R-HSA-389957|reactome:R-HSA-389960|reactome:R-HSA-390450|reactome:R-HSA-390471|ensembl:ENSG00000156261(gene)|ensembl:ENST00000286788(transcript)|go:"GO:0002199"(zona pellucida receptor complex)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005832"(chaperonin-containing T-complex)|go:"GO:0005874"(microtubule)|go:"GO:0005929"(cilium)|go:"GO:0006457"(protein folding)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0016887"(ATP hydrolysis activity)|reactome:R-HSA-6798695|reactome:R-HSA-6814122|reactome:R-HSA-5620922|dip:DIP-38124N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/TlB7Gk2Z9GPvfV3JBE0nWUF34Y9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BR76 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351152|uniprotkb:B2RD45|ensembl:ENSP00000340211|ensembl:ENSP00000377471 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cor1b_human(display_long)|uniprotkb:CORO1B(gene name)|psi-mi:CORO1B(display_short)|uniprotkb:Coronin-2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001018080.1|refseq:NP_065174.1|ensembl:ENSG00000172725(gene)|ensembl:ENST00000341356(transcript)|ensembl:ENST00000393893(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0016477"(cell migration)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031252"(cell leading edge)|go:"GO:0031529"(ruffle organization)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0042060"(wound healing)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071672"(negative regulation of smooth muscle cell chemotaxis)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0071944"(cell periphery)|go:"GO:0090135"(actin filament branching)|go:"GO:1902463"(protein localization to cell leading edge)|go:"GO:2000394"(positive regulation of lamellipodium morphogenesis)|interpro:IPR001680(WD40 repeat)|interpro:IPR015048(Region of unknown function DUF1899)|interpro:IPR015505(Coronin)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR019775|interpro:IPR027340|interpro:IPR036322|mint:Q9BR76|go:"GO:0035767"(endothelial cell chemotaxis)|dip:DIP-33176N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:80hrtgIbLoisOZLGgfaa1TLBFMg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P55010 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-286450|uniprotkb:Q9H5N2|uniprotkb:Q9UG48|uniprotkb:Q53XB3|ensembl:ENSP00000216554|ensembl:ENSP00000376477|ensembl:ENSP00000453743 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:if5_human(display_long)|uniprotkb:EIF5(gene name)|psi-mi:EIF5(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001960.2|refseq:NP_892116.2|ensembl:ENSG00000100664(gene)|ensembl:ENST00000216554(transcript)|ensembl:ENST00000392715(transcript)|ensembl:ENST00000558506(transcript)|go:"GO:0001731"(formation of translation preinitiation complex)|go:"GO:0001732"(formation of cytoplasmic translation initiation complex)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005092"(GDP-dissociation inhibitor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0045296"(cadherin binding)|go:"GO:0071074"(eukaryotic initiation factor eIF2 binding)|go:"GO:0090630"(activation of GTPase activity)|interpro:IPR002735(Translation initiation factor IF2/IF5)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR016189(Translation initiation factor IF2/IF5, N-terminal)|interpro:IPR016190(Translation initiation factor IF2/IF5, zinc-binding)|mint:P55010|rcsb pdb:2E9H|rcsb pdb:2G2K|rcsb pdb:2IU1|reactome:R-HSA-72702|reactome:R-HSA-72706 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lM5AZJWJOQGbxADfl8MGCx3JAXc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:A6NKD9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2561671|ensembl:ENSP00000369592 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cc85c_human(display_long)|uniprotkb:CCDC85C(gene name)|psi-mi:CCDC85C(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001138467.1|ensembl:ENSG00000205476(gene)|ensembl:ENST00000380243(transcript)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0043296"(apical junction complex)|interpro:IPR019359|dip:DIP-56878N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:hirZjKmej+uVQdCPF/NFOwhLkos9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q16643 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351394|uniprotkb:Q9UFZ5|uniprotkb:B2RBG0|ensembl:ENSP00000308532|intact:EBI-4404710|uniprotkb:A8MV58 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dreb_human(display_long)|uniprotkb:DBN1(gene name)|psi-mi:DBN1(display_short)|uniprotkb:Developmentally-regulated brain protein(gene name synonym)|uniprotkb:D0S117E(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004386.2|refseq:NP_543157.1|refseq:XP_005265884.1|ensembl:ENSG00000113758(gene)|ensembl:ENST00000309007(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0003779"(actin binding)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005921"(gap junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0010643"(cell communication by chemical coupling)|go:"GO:0010644"(cell communication by electrical coupling)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030027"(lamellipodium)|go:"GO:0042641"(actomyosin)|go:"GO:0030425"(dendrite)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048168"(regulation of neuronal synaptic plasticity)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0051015"(actin filament binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:1902685"(positive regulation of receptor localization to synapse)|interpro:IPR002108(Actin-binding, cofilin/tropomyosin type)|interpro:IPR028438|interpro:IPR029006|mint:Q16643|go:"GO:0030426"(growth cone)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031915"(positive regulation of synaptic plasticity)|rcsb pdb:5Y1Z|rcsb pdb:5ZZ9|reactome:R-HSA-9013405|reactome:R-HSA-9013407|reactome:R-HSA-9013418|reactome:R-HSA-9013422|go:"GO:0032507"(maintenance of protein location in cell)|refseq:XP_016864629.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0+VPJM5mTuG2jzmzGG3iLswmCUc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TDM6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-715138|uniprotkb:Q149N1|uniprotkb:Q5T1H7|uniprotkb:Q5T1H8|uniprotkb:Q6DKG3|uniprotkb:Q86WC0|uniprotkb:Q8TDM7|uniprotkb:Q9UE73|uniprotkb:Q9Y4E3|uniprotkb:A6H8Y3|ensembl:ENSP00000361467|ensembl:ENSP00000484894 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dlg5_human(display_long)|uniprotkb:Placenta and prostate DLG(gene name synonym)|uniprotkb:Discs large protein P-dlg(gene name synonym)|uniprotkb:DLG5(gene name)|psi-mi:DLG5(display_short)|uniprotkb:KIAA0583(gene name synonym)|uniprotkb:PDLG(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004738.3|refseq:XP_016872403.1|refseq:XP_011538647.1|ensembl:ENSG00000151208(gene)|ensembl:ENSG00000274429(gene)|ensembl:ENST00000372391(transcript)|ensembl:ENST00000614211(transcript)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|refseq:XP_006718119.1|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030054"(cell junction)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0030901"(midbrain development)|go:"GO:0035331"(negative regulation of hippo signaling)|go:"GO:0035332"(positive regulation of hippo signaling)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0036064"(ciliary basal body)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045176"(apical protein localization)|go:"GO:0045186"(zonula adherens assembly)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051965"(positive regulation of synapse assembly)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0072205"(metanephric collecting duct development)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR001315(Caspase Recruitment)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR006907(Protein of unknown function DUF622)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR011029(DEATH-like)|interpro:IPR027417|interpro:IPR035537|interpro:IPR036028|interpro:IPR036034|mint:Q8TDM6|rcsb pdb:1UIT|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273|dip:DIP-41450N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:UmBC3Fli9huOHBiaXBtfPogAQCE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P29692 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-358607|uniprotkb:Q969J1|uniprotkb:D3DWK3|intact:EBI-748782|uniprotkb:Q96I38|ensembl:ENSP00000317399|ensembl:ENSP00000378551|ensembl:ENSP00000388261|ensembl:ENSP00000433412|ensembl:ENSP00000433611|ensembl:ENSP00000434448|ensembl:ENSP00000434872|ensembl:ENSP00000436542|ensembl:ENSP00000436933|ensembl:ENSP00000478340|ensembl:ENSP00000479653|ensembl:ENSP00000483527|ensembl:ENSP00000487680|intact:EBI-11048966|uniprotkb:Q4VBZ6|uniprotkb:B4DDU4|uniprotkb:E9PBQ9 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ef1d_human(display_long)|uniprotkb:EEF1D(gene name)|psi-mi:EEF1D(display_short)|uniprotkb:EF1D(gene name synonym)|uniprotkb:Antigen NY-CO-4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001123528.1|refseq:NP_001123527.1|refseq:NP_001123529.1|refseq:NP_001951.2|refseq:XP_011515207.1|refseq:XP_011515208.1|ensembl:ENST00000419152(transcript)|ensembl:ENST00000529272(transcript)|ensembl:ENST00000530191(transcript)|ensembl:ENST00000530445(transcript)|ensembl:ENST00000531218(transcript)|ensembl:ENST00000533494(transcript)|ensembl:ENST00000534380(transcript)|ensembl:ENST00000614575(transcript)|ensembl:ENST00000615067(transcript)|ensembl:ENST00000615698(transcript)|ensembl:ENST00000632587(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003677"(DNA binding)|go:"GO:0003746"(translation elongation factor activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005853"(eukaryotic translation elongation factor 1 complex)|go:"GO:0006414"(translational elongation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0009299"(mRNA transcription)|go:"GO:0010941"(regulation of cell death)|go:"GO:0031072"(heat shock protein binding)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0045296"(cadherin binding)|go:"GO:0071479"(cellular response to ionizing radiation)|go:"GO:0140297"(DNA-binding transcription factor binding)|interpro:IPR001326(Translation elongation factor EF1B, beta/delta chains, conserved site)|interpro:IPR014038(Translation elongation factor EF1B, beta and delta chains, guanine nucleotide exchange)|interpro:IPR014717(Translation elongation factor EF1B/ribosomal protein S6)|interpro:IPR018940|interpro:IPR036219|mint:P29692|rcsb pdb:2MVM|rcsb pdb:2MVN|rcsb pdb:2N51|rcsb pdb:5JPO|reactome:R-HSA-156842|ensembl:ENSG00000104529(gene)|ensembl:ENSG00000273594(gene)|ensembl:ENST00000317198(transcript)|ensembl:ENST00000395119(transcript)|refseq:NP_001304672.1|refseq:NP_001182132.1|refseq:NP_001276879.1|refseq:XP_006716585.1|refseq:XP_006716586.1|refseq:XP_006716587.1|refseq:XP_006716588.1|refseq:XP_005250880.1|refseq:NP_001317575.1|refseq:XP_016868659.1|refseq:NP_001123525.2|refseq:NP_115754.3 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:9Mzpfofeg2W/GQ/JfjFxcCFJnKg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NWQ8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2828115|uniprotkb:Q2M1Z9|uniprotkb:Q9NYK0|uniprotkb:Q5BKU4|uniprotkb:A8K1A3|ensembl:ENSP00000220597 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:phag1_human(display_long)|uniprotkb:PAG1(gene name)|psi-mi:PAG1(display_short)|uniprotkb:CBP(gene name synonym)|uniprotkb:PAG(gene name synonym)|uniprotkb:Csk-binding protein(gene name synonym)|uniprotkb:Transmembrane adapter protein PAG(gene name synonym)|uniprotkb:Transmembrane phosphoprotein Cbp(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060910.3|ensembl:ENSG00000076641(gene)|ensembl:ENST00000220597(transcript)|go:"GO:0002250"(adaptive immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0016021"(integral component of membrane)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0045121"(membrane raft)|go:"GO:0050863"(regulation of T cell activation)|go:"GO:0050868"(negative regulation of T cell activation)|interpro:IPR032748|reactome:R-HSA-180292|reactome:R-HSA-202427|refseq:XP_016869129.1|refseq:XP_016869130.1|refseq:XP_016869131.1|refseq:XP_016869132.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ziOdrGbpb1Fc8rOj+N9hsEVxdAs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q99569 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-726447|uniprotkb:Q86W91|ensembl:ENSP00000374409 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkp4_human(display_long)|uniprotkb:p0071(gene name synonym)|uniprotkb:PKP4(gene name)|psi-mi:PKP4(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001005476.1|refseq:NP_003619.2|refseq:NP_001291898.1|refseq:NP_001291899.1|refseq:XP_011510318.1|ensembl:ENST00000389757|ensembl:ENSP00000374407|ensembl:ENSP00000374409|ensembl:ENSG00000144283(gene)|ensembl:ENST00000389759(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0001533"(cornified envelope)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0030155"(regulation of cell adhesion)|go:"GO:0030496"(midbody)|go:"GO:0032467"(positive regulation of cytokinesis)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051233"(spindle midzone)|go:"GO:0072686"(mitotic spindle)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028443|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9696264|reactome:R-HSA-9696270|reactome:R-HSA-9696273 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ii0+JmsNuDEPLxwiTJ8utGeaq4Q9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P04075 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-709613|uniprotkb:Q6FH76|uniprotkb:Q96B15|uniprotkb:Q9BWD9|uniprotkb:B4DXI7|uniprotkb:Q6FI10|uniprotkb:Q9UCN2|ensembl:ENSP00000400452|ensembl:ENSP00000455700|ensembl:ENSP00000455800|ensembl:ENSP00000494188 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:aldoa_human(display_long)|uniprotkb:Muscle-type aldolase(gene name synonym)|uniprotkb:Lung cancer antigen NY-LU-1(gene name synonym)|uniprotkb:ALDOA(gene name)|psi-mi:ALDOA(display_short)|uniprotkb:ALDA(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000025.1|refseq:NP_001121089.1|refseq:NP_001230106.1|refseq:NP_908930.1|refseq:NP_908932.1|refseq:XP_011544070.1|ensembl:ENSG00000149925(gene)|ensembl:ENST00000412304(transcript)|ensembl:ENST00000563060(transcript)|ensembl:ENST00000569545(transcript)|ensembl:ENST00000643777(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0004332"(fructose-bisphosphate aldolase activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0006000"(fructose metabolic process)|go:"GO:0006096"(glycolytic process)|go:"GO:0006754"(ATP biosynthetic process)|go:"GO:0006941"(striated muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007339"(binding of sperm to zona pellucida)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0030388"(fructose 1,6-bisphosphate metabolic process)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0031430"(M band)|go:"GO:0031674"(I band)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0046716"(muscle cell cellular homeostasis)|go:"GO:0051289"(protein homotetramerization)|go:"GO:0061827"(sperm head)|go:"GO:0070061"(fructose binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904724"(tertiary granule lumen)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000741(Fructose-bisphosphate aldolase, class-I)|interpro:IPR013785(Aldolase-type TIM barrel)|interpro:IPR029768|mint:P04075|rcsb pdb:1ALD|rcsb pdb:2ALD|rcsb pdb:4ALD|rcsb pdb:5KY6|reactome:R-HSA-114608|reactome:R-HSA-6798695|reactome:R-HSA-70171|reactome:R-HSA-70263 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/UgTtKPQj2ZyKznKIfE9OVUcDFI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q05682 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1642116|uniprotkb:Q13978|uniprotkb:Q13979|uniprotkb:Q14741|uniprotkb:Q14742|uniprotkb:Q9UD91|uniprotkb:A8K0X1|ensembl:ENSP00000354826 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cald1_human(display_long)|uniprotkb:CALD1(gene name)|psi-mi:CALD1(display_short)|uniprotkb:CAD(gene name synonym)|uniprotkb:CDM(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004333.1|refseq:NP_149129.2|refseq:NP_149130.1|refseq:NP_149131.1|refseq:NP_149347.2|refseq:XP_016868140.1|refseq:XP_016868141.1|ensembl:ENSG00000122786(gene)|ensembl:ENST00000361675(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0017022"(myosin binding)|go:"GO:0030016"(myofibril)|go:"GO:0030478"(actin cap)|go:"GO:0045296"(cadherin binding)|go:"GO:0051017"(actin filament bundle assembly)|interpro:IPR006017(Caldesmon)|interpro:IPR006018(Caldesmon and lymphocyte specific protein)|mint:Q05682|reactome:R-HSA-445355 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fvHmtqnSPixs/3150s7LOA1Bvpw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6IQ23 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2125301|uniprotkb:Q86VZ7|uniprotkb:B4DK33|uniprotkb:B4DWC3|intact:EBI-28977101|ensembl:ENSP00000347883 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkha7_human(display_long)|uniprotkb:PLEKHA7(gene name)|psi-mi:PLEKHA7(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_778228.3|ensembl:ENSP00000347883|refseq:NP_001316559.1|refseq:NP_001316560.1|ensembl:ENSG00000166689(gene)|ensembl:ENST00000355661(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005915"(zonula adherens)|go:"GO:0030054"(cell junction)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045218"(zonula adherens maintenance)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070097"(delta-catenin binding)|go:"GO:0090136"(epithelial cell-cell adhesion)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|rcsb pdb:7KJO|rcsb pdb:7KJZ|rcsb pdb:7KK7 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:AqLJ+GSULYT7MByw7FZAgPXxir49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y6M5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10982148|ensembl:ENSP00000355968|uniprotkb:Q0VAK9|uniprotkb:Q9BZF6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:znt1_human(display_long)|uniprotkb:SLC30A1(gene name)|psi-mi:SLC30A1(display_short)|uniprotkb:Solute carrier family 30 member 1(gene name synonym)|uniprotkb:ZNT1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_067017.2|ensembl:ENSG00000170385(gene)|ensembl:ENST00000367001(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005385"(zinc ion transmembrane transporter activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005886"(plasma membrane)|go:"GO:0006829"(zinc ion transport)|go:"GO:0006874"(cellular calcium ion homeostasis)|go:"GO:0006882"(cellular zinc ion homeostasis)|go:"GO:0010312"(detoxification of zinc ion)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019855"(calcium channel inhibitor activity)|go:"GO:0030315"(T-tubule)|go:"GO:0031965"(nuclear membrane)|go:"GO:0046929"(negative regulation of neurotransmitter secretion)|go:"GO:0070509"(calcium ion import)|go:"GO:0070574"(cadmium ion transmembrane transport)|go:"GO:0071577"(zinc ion transmembrane transport)|go:"GO:0071584"(negative regulation of zinc ion transmembrane import)|go:"GO:0071585"(detoxification of cadmium ion)|go:"GO:0090281"(negative regulation of calcium ion import)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0099061"(integral component of postsynaptic density membrane)|interpro:IPR002524(Cation efflux protein)|interpro:IPR027469|interpro:IPR036837|mint:Q9Y6M5|reactome:R-HSA-435368 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XL8LmzhYwIWnN1yPFHnDkoJg2TE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15020 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-308449|uniprotkb:O14872|uniprotkb:O14873|ensembl:ENSP00000311489|ensembl:ENSP00000432568|ensembl:ENSP00000480692|ensembl:ENSP00000508362 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sptn2_human(display_long)|uniprotkb:SPTBN2(gene name)|psi-mi:SPTBN2(display_short)|uniprotkb:KIAA0302(gene name synonym)|uniprotkb:Beta-III spectrin(gene name synonym)|uniprotkb:SCA5(gene name synonym)|uniprotkb:Spinocerebellar ataxia 5 protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000173898(gene)|ensembl:ENST00000309996(transcript)|ensembl:ENST00000533211(transcript)|ensembl:ENST00000611817(transcript)|ensembl:ENST00000647510(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005829"(cytosol)|go:"GO:0007416"(synapse assembly)|go:"GO:0008091"(spectrin)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0021692"(cerebellar Purkinje cell layer morphogenesis)|go:"GO:0030534"(adult behavior)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0098688"(parallel fiber to Purkinje cell synapse)|go:"GO:0098793"(presynapse)|go:"GO:0098918"(structural constituent of synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|go:"GO:0099189"(postsynaptic spectrin-associated cytoskeleton)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001605(Spectrin/pleckstrin-like)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016343(Spectrin, beta subunit)|interpro:IPR018159|interpro:IPR036872|interpro:IPR041681|mint:O15020|rcsb pdb:1WJM|rcsb pdb:1WYQ|rcsb pdb:6ANU|reactome:R-HSA-2132295|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6807878|refseq:XP_005274249.1|refseq:XP_005274250.1|refseq:XP_006718734.1|refseq:XP_016873663.1|refseq:XP_016873664.1|refseq:XP_016873665.1|refseq:XP_016873666.1|refseq:XP_016873667.1|dip:DIP-47270N|refseq:NP_008877.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Wfzccja70pnee8sDDc0TCmO6g0I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9BW04 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2320464|uniprotkb:Q658X3|intact:EBI-2696030|uniprotkb:C9JV41|ensembl:ENSP00000352447 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sarg_human(display_long)|uniprotkb:C1orf116(gene name synonym)|uniprotkb:SARG(gene name)|psi-mi:SARG(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011508275.1|refseq:XP_006711593.1|refseq:NP_001077393.1|refseq:NP_076427.2|refseq:XP_005273316.1|ensembl:ENSG00000182795(gene)|ensembl:ENST00000359470(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0070062"(extracellular exosome)|interpro:IPR026152 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:AfOz1jkLOyP30lMqKpYzJ7mTrj49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q04637 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-73711|uniprotkb:O43177|uniprotkb:O95066|uniprotkb:Q5HYG0|uniprotkb:Q6ZN21|uniprotkb:Q8N102|intact:EBI-11020102|uniprotkb:D3DNT4|uniprotkb:D3DNT5|uniprotkb:D3DNT2|uniprotkb:E9PFM1|uniprotkb:G5E9S1|intact:EBI-28974642|ensembl:ENSP00000316879 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:if4g1_human(display_long)|uniprotkb:p220(gene name synonym)|uniprotkb:EIF4G1(gene name)|psi-mi:EIF4G1(display_short)|uniprotkb:EIF4G(gene name synonym)|uniprotkb:EIF4GI(gene name synonym)|uniprotkb:EIF4F(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000342981|ensembl:ENSP00000343450|ensembl:ENSP00000316879|ensembl:ENST00000350481|ensembl:ENSP00000317600|ensembl:ENST00000352767|ensembl:ENSP00000338020|ensembl:ENST00000382330|ensembl:ENSP00000371767|ensembl:ENST00000392537|ensembl:ENSP00000376320|ensembl:ENST00000414031|ensembl:ENSP00000391935|ensembl:ENST00000424196|ensembl:ENSP00000416255|ensembl:ENST00000434061|ensembl:ENSP00000411826|refseq:NP_886553.3|refseq:NP_937884.1|refseq:NP_937885.1|refseq:NP_004944.3|dip:DIP-1161N|ensembl:ENSG00000114867(gene)|ensembl:ENST00000346169(transcript)|go:"GO:0001662"(behavioral fear response)|go:"GO:0002191"(cap-dependent translational initiation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008135"(translation factor activity, RNA binding)|go:"GO:0008190"(eukaryotic initiation factor 4E binding)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0010507"(negative regulation of autophagy)|go:"GO:0010801"(negative regulation of peptidyl-threonine phosphorylation)|go:"GO:0010942"(positive regulation of cell death)|go:"GO:0016020"(membrane)|go:"GO:0016281"(eukaryotic translation initiation factor 4F complex)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031369"(translation initiation factor binding)|go:"GO:0031669"(cellular response to nutrient levels)|go:"GO:0032270"(positive regulation of cellular protein metabolic process)|go:"GO:0032502"(developmental process)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0034645"(cellular macromolecule biosynthetic process)|go:"GO:0036493"(positive regulation of translation in response to endoplasmic reticulum stress)|go:"GO:0042802"(identical protein binding)|go:"GO:0045666"(positive regulation of neuron differentiation)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0060964"(regulation of gene silencing by miRNA)|go:"GO:0080135"(regulation of cellular response to stress)|go:"GO:0097009"(energy homeostasis)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1905537"(positive regulation of eukaryotic translation initiation factor 4F complex assembly)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:1905612"(positive regulation of mRNA cap binding)|go:"GO:1905618"(positive regulation of miRNA-mediated gene silencing by inhibition of translation)|go:"GO:1905696"(regulation of polysome binding)|interpro:IPR003307(eIF4-gamma/eIF5/eIF2-epsilon)|interpro:IPR003890(MIF4G-like, type 3)|interpro:IPR003891(Initiation factor eIF-4 gamma, MA3)|interpro:IPR016021(MIF4-like, type 1/2/3)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR037584|mint:Q04637|rcsb pdb:1LJ2|rcsb pdb:1UG3|rcsb pdb:2W97|rcsb pdb:4AZA|rcsb pdb:4F02|rcsb pdb:5EHC|rcsb pdb:5EI3|rcsb pdb:5EIR|rcsb pdb:5T46|rcsb pdb:6ZMW|reactome:R-HSA-1169408|reactome:R-HSA-156827|reactome:R-HSA-166208|reactome:R-HSA-429947|reactome:R-HSA-450408|reactome:R-HSA-72649|reactome:R-HSA-72662|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0UfVxxWOLUvrvFfcteeTc2RrbhA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IZP0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-375446|uniprotkb:O15147|uniprotkb:O76049|uniprotkb:O95060|uniprotkb:Q5W070|uniprotkb:Q5W072|uniprotkb:Q8TB63|uniprotkb:Q96S81|uniprotkb:Q9NXZ9|uniprotkb:Q9NYB8|intact:EBI-28968938|ensembl:ENSP00000365312|uniprotkb:A9Z1Y6|uniprotkb:Q5T2R3|uniprotkb:Q5T2R4|uniprotkb:Q5T2R6|uniprotkb:Q5T2R7|uniprotkb:B4DQ58|uniprotkb:Q5T2R9|uniprotkb:B3KX62|uniprotkb:H7BXI6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:abi1_human(display_long)|uniprotkb:ABI1(gene name)|psi-mi:ABI1(display_short)|uniprotkb:SSH3BP1(gene name synonym)|uniprotkb:Abelson interactor 1(gene name synonym)|uniprotkb:Spectrin SH3 domain-binding protein 1(gene name synonym)|uniprotkb:Eps8 SH3 domain-binding protein(gene name synonym)|uniprotkb:e3B1(gene name synonym)|uniprotkb:Nap1-binding protein(gene name synonym)|uniprotkb:Abl-binding protein 4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001012768.1|refseq:NP_001012769.1|refseq:NP_001012770.1|refseq:NP_001171590.1|refseq:NP_001171591.1|go:"GO:0030027"(lamellipodium)|go:"GO:0030296"(protein tyrosine kinase activator activity)|go:"GO:0030426"(growth cone)|go:"GO:0031209"(SCAR complex)|go:"GO:0032433"(filopodium tip)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072673"(lamellipodium morphogenesis)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR001452(Src homology-3)|interpro:IPR012849(Abl-interactor, homeo-domain homologous region)|interpro:IPR028456|interpro:IPR028457|interpro:IPR035725|interpro:IPR036028|mint:Q8IZP0|ensembl:ENST00000376142(transcript)|go:"GO:0001756"(somitogenesis)|ensembl:ENSG00000136754(gene)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008154"(actin polymerization or depolymerization)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|refseq:NP_001171592.1|refseq:NP_001171593.1|refseq:NP_001171594.1|refseq:NP_001171595.1|refseq:NP_005461.2|ensembl:ENST00000346832|ensembl:ENSP00000279599|ensembl:ENST00000359188|ensembl:ENSP00000352114|ensembl:ENST00000376137|ensembl:ENSP00000365307|ensembl:ENST00000376138|ensembl:ENSP00000365308|ensembl:ENST00000376139|ensembl:ENSP00000365309|ensembl:ENST00000376140|ensembl:ENSP00000365310|ensembl:ENSP00000365312|ensembl:ENST00000376166|ensembl:ENSP00000365336|ensembl:ENST00000376170|ensembl:ENSP00000365340|ensembl:ENST00000490841|ensembl:ENSP00000440101|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|refseq:NP_001171596.1|refseq:NP_001171587.1|dip:DIP-31118N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:mO2D5R8ZlYmsh+fXdJpaHZOssfs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q63ZY3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2556193|uniprotkb:Q9H8S4|uniprotkb:Q6GUF5|uniprotkb:Q9NUP0|uniprotkb:Q3KQZ3|uniprotkb:B0I1P4|uniprotkb:Q9P210|ensembl:ENSP00000465650 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:kank2_human(display_long)|uniprotkb:ANKRD25(gene name synonym)|uniprotkb:KIAA1518(gene name synonym)|uniprotkb:MXRA3(gene name synonym)|uniprotkb:SIP(gene name synonym)|uniprotkb:Ankyrin repeat domain-containing protein 25(gene name synonym)|uniprotkb:SRC-1-interacting protein(gene name synonym)|uniprotkb:Matrix-remodeling-associated protein 3(gene name synonym)|uniprotkb:KANK2(gene name)|psi-mi:KANK2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001129663.1|refseq:NP_056308.3|rcsb pdb:6TMD|ensembl:ENSG00000197256(gene)|ensembl:ENST00000586659(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0006915"(apoptotic process)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0033147"(negative regulation of intracellular estrogen receptor signaling pathway)|go:"GO:0035023"(regulation of Rho protein signal transduction)|go:"GO:0043069"(negative regulation of programmed cell death)|go:"GO:0070563"(negative regulation of vitamin D receptor signaling pathway)|go:"GO:0072073"(kidney epithelium development)|go:"GO:0090521"(glomerular visceral epithelial cell migration)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR021939|interpro:IPR036770|mint:Q63ZY3|rcsb pdb:4HBD|rcsb pdb:5YBV|refseq:NP_001316380.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:5lZ6UWmx5+N6B1B/xTmVfvxA7Ag9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8NFJ5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2561555|ensembl:ENSP00000014914|uniprotkb:O95357|uniprotkb:B3KV45 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rai3_human(display_long)|uniprotkb:GPRC5A(gene name)|psi-mi:GPRC5A(display_short)|uniprotkb:GPCR5A(gene name synonym)|uniprotkb:RAI3(gene name synonym)|uniprotkb:RAIG1(gene name synonym)|uniprotkb:G-protein coupled receptor family C group 5 member A(gene name synonym)|uniprotkb:Retinoic acid-induced gene 1 protein(gene name synonym)|uniprotkb:Phorbol ester induced gene 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000013588(gene)|ensembl:ENST00000014914(transcript)|go:"GO:0004930"(G protein-coupled receptor activity)|go:"GO:0005730"(nucleolus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0007165"(signal transduction)|go:"GO:0007175"(negative regulation of epidermal growth factor-activated receptor activity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0031982"(vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043235"(receptor complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR017978|refseq:NP_003970.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:34/gAVA1PebkQgzu1veBTClSGcE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NYL9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-352614|ensembl:ENSP00000308753|uniprotkb:Q9NT43|uniprotkb:Q9NZR0|uniprotkb:B2R6G7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tmod3_human(display_long)|uniprotkb:TMOD3(gene name)|psi-mi:TMOD3(display_short)|uniprotkb:Ubiquitous tropomodulin(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000138594(gene)|ensembl:ENST00000308580(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005523"(tropomyosin binding)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005865"(striated muscle thin filament)|go:"GO:0005912"(adherens junction)|go:"GO:0006936"(muscle contraction)|go:"GO:0007015"(actin filament organization)|go:"GO:0030016"(myofibril)|go:"GO:0030239"(myofibril assembly)|refseq:NP_055362.1|go:"GO:0048821"(erythrocyte development)|go:"GO:0051694"(pointed-end actin filament capping)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1901992"(positive regulation of mitotic cell cycle phase transition)|interpro:IPR004934(Tropomodulin)|interpro:IPR030133|interpro:IPR032675|mint:Q9NYL9|reactome:R-HSA-390522|reactome:R-HSA-9013418|reactome:R-HSA-9696264|refseq:XP_016877576.1|refseq:XP_016877577.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:crEfCAAepSPAE8ByBpD4Sr14P5I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96KQ4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1105153|uniprotkb:B2RMX5|uniprotkb:O94870|ensembl:ENSP00000202556 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:aspp1_human(display_long)|uniprotkb:PPP1R13B(gene name)|psi-mi:PPP1R13B(display_short)|uniprotkb:ASPP1(gene name synonym)|uniprotkb:KIAA0771(gene name synonym)|uniprotkb:Protein phosphatase 1 regulatory subunit 13B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000088808(gene)|ensembl:ENST00000202556(transcript)|go:"GO:0002039"(p53 binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0045786"(negative regulation of cell cycle)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:1901216"(positive regulation of neuron death)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028319|interpro:IPR029071|interpro:IPR036028|interpro:IPR036770|rcsb pdb:6HL5|reactome:R-HSA-139915|reactome:R-HSA-6803204|reactome:R-HSA-6803205|reactome:R-HSA-6803211|reactome:R-HSA-6804759|refseq:NP_056131.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:68vrjCXCm2NiwUih4QbAqeT3Jj49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13492 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2803688|uniprotkb:Q86XZ9|uniprotkb:O60700|uniprotkb:Q6GMQ6|intact:EBI-28967113|ensembl:ENSP00000377015|uniprotkb:B4DTM3|uniprotkb:E9PN05|uniprotkb:F8VPG7|uniprotkb:Q4LE54 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pical_human(display_long)|uniprotkb:CALM(gene name synonym)|uniprotkb:Clathrin assembly lymphoid myeloid leukemia protein(gene name synonym)|uniprotkb:PICALM(gene name)|psi-mi:PICALM(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000356360|ensembl:ENSP00000348718|ensembl:ENSP00000377015|ensembl:ENST00000526033|ensembl:ENSP00000433846|ensembl:ENST00000528398|ensembl:ENSP00000434884|ensembl:ENST00000532317|ensembl:ENSP00000436958|go:"GO:0005769"(early endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0006897"(endocytosis)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0007409"(axonogenesis)|go:"GO:0007611"(learning or memory)|go:"GO:0008021"(synaptic vesicle)|go:"GO:0009986"(cell surface)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016185"(synaptic vesicle budding from presynaptic endocytic zone membrane)|go:"GO:0016188"(synaptic vesicle maturation)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0016197"(endosomal transport)|go:"GO:0030097"(hemopoiesis)|go:"GO:0030100"(regulation of endocytosis)|go:"GO:0030132"(clathrin coat of coated pit)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030276"(clathrin binding)|go:"GO:0031224"(intrinsic component of membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0005634"(nucleus)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|go:"GO:1905224"(clathrin-coated pit assembly)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR008942(ENTH/VHS)|interpro:IPR011417(ANTH)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR014712(Clathrin adaptor, phosphoinositide-binding, GAT-like)|interpro:IPR030412|mint:Q13492|reactome:R-HSA-432722|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-9696264|go:"GO:0032880"(regulation of protein localization)|go:"GO:0035459"(vesicle cargo loading)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045334"(clathrin-coated endocytic vesicle)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048156"(tau protein binding)|go:"GO:0048261"(negative regulation of receptor-mediated endocytosis)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0032050"(clathrin heavy chain binding)|ensembl:ENSG00000073921(gene)|ensembl:ENST00000393346(transcript)|go:"GO:0000149"(SNARE binding)|go:"GO:0001540"(amyloid-beta binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070381"(endosome to plasma membrane transport vesicle)|go:"GO:0072583"(clathrin-dependent endocytosis)|go:"GO:0090647"(modulation of age-related behavioral decline)|go:"GO:0097418"(neurofibrillary tangle)|go:"GO:0097494"(regulation of vesicle size)|go:"GO:0097753"(membrane bending)|go:"GO:0098894"(extrinsic component of presynaptic endocytic zone membrane)|go:"GO:0150093"(amyloid-beta clearance by transcytosis)|go:"GO:1901216"(positive regulation of neuron death)|go:"GO:1902004"(positive regulation of amyloid-beta formation)|go:"GO:1902959"(regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902961"(positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:1902963"(negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process)|go:"GO:0055072"(iron ion homeostasis)|refseq:NP_001008660.1|refseq:NP_001193875.1|refseq:NP_001193876.1|refseq:NP_009097.2|refseq:XP_005274388.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:UIZhYyYqmBCyN4xwPCl9PeCdK8Q9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y6W5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4290615|uniprotkb:O60794|uniprotkb:Q9UDY7|intact:EBI-28973998|ensembl:ENSP00000483313|uniprotkb:B4DZN0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:wasf2_human(display_long)|uniprotkb:WASF2(gene name)|psi-mi:WASF2(display_short)|uniprotkb:WAVE2(gene name synonym)|uniprotkb:Protein WAVE-2(gene name synonym)|uniprotkb:Verprolin homology domain-containing protein 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_008921.1|ensembl:ENST00000536657|ensembl:ENSP00000439883|ensembl:ENSP00000483313|go:"GO:2000601"(positive regulation of Arp2/3 complex-mediated actin nucleation)|interpro:IPR003124(Actin-binding WH2)|interpro:IPR028288|mint:Q9Y6W5|rcsb pdb:2A40|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013423|reactome:R-HSA-9664422|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|ensembl:ENSG00000158195(gene)|ensembl:ENST00000618852(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001667"(ameboidal-type cell migration)|go:"GO:0001726"(ruffle)|go:"GO:0003779"(actin binding)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006897"(endocytosis)|go:"GO:0007188"(adenylate cyclase-modulating G protein-coupled receptor signaling pathway)|go:"GO:0010592"(positive regulation of lamellipodium assembly)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016601"(Rac protein signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030048"(actin filament-based movement)|go:"GO:0031209"(SCAR complex)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0035855"(megakaryocyte development)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071933"(Arp2/3 complex binding)|go:"GO:0072673"(lamellipodium morphogenesis)|refseq:NP_001188333.1|dip:DIP-41817N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lRPT4syjPdKz2JoqWQQm3xw4hWc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P17900 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3046641|ensembl:ENSP00000349687|uniprotkb:Q14426|uniprotkb:Q14428|uniprotkb:D3DQH6|uniprotkb:B2R699|uniprotkb:Q6LBL5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sap3_human(display_long)|uniprotkb:GM2A(gene name)|psi-mi:GM2A(display_short)|uniprotkb:Cerebroside sulfate activator protein(gene name synonym)|uniprotkb:GM2-AP(gene name synonym)|uniprotkb:Sphingolipid activator protein 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000196743(gene)|ensembl:ENST00000357164(transcript)|go:"GO:0005319"(lipid transporter activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0006687"(glycosphingolipid metabolic process)|go:"GO:0006689"(ganglioside catabolic process)|go:"GO:0006869"(lipid transport)|go:"GO:0007611"(learning or memory)|go:"GO:0009313"(oligosaccharide catabolic process)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0016004"(phospholipase activator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019915"(lipid storage)|go:"GO:0030290"(sphingolipid activator protein activity)|go:"GO:0032428"(beta-N-acetylgalactosaminidase activity)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050885"(neuromuscular process controlling balance)|go:"GO:0051345"(positive regulation of hydrolase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003172(MD-2-related lipid-recognition)|interpro:IPR028996|interpro:IPR036846|rcsb pdb:1G13|rcsb pdb:1PU5|rcsb pdb:1PUB|rcsb pdb:2AF9|rcsb pdb:2AG2|rcsb pdb:2AG4|rcsb pdb:2AG9|reactome:R-HSA-1660662|reactome:R-HSA-6798695|rcsb pdb:1TJJ|refseq:NP_000396.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XN1EL9XjhFB+ma/Jc1mYshhMMvY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13480 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-517684|uniprotkb:Q4W5G2|uniprotkb:Q6P1W2|uniprotkb:A8K152|ensembl:ENSP00000262994 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:gab1_human(display_long)|uniprotkb:Growth factor receptor bound protein 2-associated protein 1(gene name synonym)|uniprotkb:GRB2-associated binder 1(gene name synonym)|uniprotkb:GAB1(gene name)|psi-mi:GAB1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000262994|ensembl:ENST00000262995|ensembl:ENSP00000262995|refseq:NP_002030.2|refseq:NP_997006.1|ensembl:ENSG00000109458(gene)|ensembl:ENST00000262994(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038084"(vascular endothelial growth factor signaling pathway)|go:"GO:0038089"(positive regulation of cell migration by vascular endothelial growth factor signaling pathway)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0090668"(endothelial cell chemotaxis to vascular endothelial growth factor)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|mint:Q13480|rcsb pdb:4QSY|reactome:R-HSA-109704|reactome:R-HSA-1236382|reactome:R-HSA-1257604|reactome:R-HSA-180292|reactome:R-HSA-1963642|reactome:R-HSA-2219530|reactome:R-HSA-5637810|reactome:R-HSA-5654689|reactome:R-HSA-5654695|reactome:R-HSA-5654710|reactome:R-HSA-5654720|reactome:R-HSA-5655253|reactome:R-HSA-5655291|reactome:R-HSA-5655302|reactome:R-HSA-6811558|reactome:R-HSA-8851907|reactome:R-HSA-8853334|reactome:R-HSA-8853338|reactome:R-HSA-8853659|reactome:R-HSA-8865999|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027276|reactome:R-HSA-9028335|reactome:R-HSA-9664565|reactome:R-HSA-9665348 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:AIK39gZJknpy3vQK/GraIpBbgzU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P18206 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-716775|uniprotkb:Q16450|uniprotkb:Q5SWX2|uniprotkb:Q7Z3B8|uniprotkb:Q8IXU7|ensembl:ENSP00000211998 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:vinc_human(display_long)|uniprotkb:Metavinculin(gene name synonym)|uniprotkb:VCL(gene name)|psi-mi:VCL(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003364.1|refseq:NP_054706.1|ensembl:ENSG00000035403(gene)|ensembl:ENST00000211998(transcript)|go:"GO:0002009"(morphogenesis of an epithelium)|go:"GO:0002102"(podosome)|go:"GO:0002162"(dystroglycan binding)|go:"GO:0003779"(actin binding)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR017997|interpro:IPR036723|mint:P18206|rcsb pdb:1RKC|rcsb pdb:1RKE|rcsb pdb:1SYQ|rcsb pdb:1TR2|rcsb pdb:1YDI|rcsb pdb:2GWW|rcsb pdb:2HSQ|rcsb pdb:2IBF|rcsb pdb:3H2U|rcsb pdb:3H2V|rcsb pdb:3JBK|rcsb pdb:3MYI|rcsb pdb:3RF3|rcsb pdb:3S90|go:"GO:0005198"(structural molecule activity)|rcsb pdb:3TJ5|rcsb pdb:3TJ6|rcsb pdb:3VF0|rcsb pdb:4DJ9|rcsb pdb:4EHP|rcsb pdb:4LN2|rcsb pdb:4LNP|rcsb pdb:4PR9|rcsb pdb:5L0C|rcsb pdb:5L0D|rcsb pdb:5L0F|rcsb pdb:5L0G|rcsb pdb:5L0H|rcsb pdb:5L0I|rcsb pdb:5L0J|rcsb pdb:5O2Q|rcsb pdb:6FUY|rcsb pdb:6UPW|rcsb pdb:7KTT|rcsb pdb:7KTU|rcsb pdb:7KTV|rcsb pdb:7KTW|reactome:R-HSA-114608|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0030032"(lamellipodium assembly)|go:"GO:0030055"(cell-substrate junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0035580"(specific granule lumen)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042383"(sarcolemma)|go:"GO:0043034"(costamere)|go:"GO:0043297"(apical junction assembly)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045121"(membrane raft)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048675"(axon extension)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0090636"(outer dense plaque of desmosome)|go:"GO:0090637"(inner dense plaque of desmosome)|go:"GO:1903140"(regulation of establishment of endothelial barrier)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904702"(regulation of protein localization to adherens junction)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:1990357"(terminal web)|interpro:IPR000633(Vinculin, conserved site)|ensembl:ENSP00000211998|ensembl:ENST00000372755|ensembl:ENSP00000361841|dip:DIP-35570N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Cs5ZD4u5mH3IHBeKWMRV4cfS+y49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96NW7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-524275|uniprotkb:Q5VXC2|uniprotkb:Q5VXC3|uniprotkb:Q68D07|uniprotkb:Q8WX20|uniprotkb:Q9P2I2|uniprotkb:Q86VE8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lrrc7_human(display_long)|uniprotkb:Protein LAP1(gene name synonym)|uniprotkb:Densin-180(gene name synonym)|uniprotkb:LRRC7(gene name)|psi-mi:LRRC7(display_short)|uniprotkb:KIAA1365(gene name synonym)|uniprotkb:LAP1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N interpro:IPR003591(Leucine-rich repeat, typical subtype)|rcsb pdb:6X5G|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043113"(receptor clustering)|go:"GO:0043194"(axon initial segment)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR036034|reactome:R-HSA-6798695|interpro:IPR032675|refseq:NP_065845.1|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR001478(PDZ/DHR/GLGF)|reactome:R-HSA-9617324|reactome:R-HSA-9620244|reactome:R-HSA-438066|reactome:R-HSA-442982|reactome:R-HSA-5673001|reactome:R-HSA-9609736 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:8HUVcF8vycpMbC6o7GWT+u9iPu49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15173 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1050125|uniprotkb:Q569H1|ensembl:ENSP00000296425|ensembl:ENSP00000429301 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pgrc2_human(display_long)|uniprotkb:Progesterone membrane-binding protein(gene name synonym)|uniprotkb:Steroid receptor protein DG6(gene name synonym)|uniprotkb:PGRMC2(gene name)|psi-mi:PGRMC2(display_short)|uniprotkb:DG6(gene name synonym)|uniprotkb:PMBP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006311.2|ensembl:ENSG00000164040(gene)|ensembl:ENST00000296425(transcript)|ensembl:ENST00000520121(transcript)|go:"GO:0003707"(steroid hormone receptor activity)|go:"GO:0005496"(steroid binding)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0012505"(endomembrane system)|go:"GO:0015232"(heme transmembrane transporter activity)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0020037"(heme binding)|go:"GO:0060612"(adipose tissue development)|interpro:IPR001199(Cytochrome b5)|interpro:IPR036400|mint:O15173|reactome:R-HSA-8980692|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013408|reactome:R-HSA-9013423 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:y8PU98eUcxnJLxobBcFL40xaprw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96FG2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-10285740|uniprotkb:Q8NAC1|uniprotkb:Q8TCK4|uniprotkb:Q8WY75|uniprotkb:Q9H6Q8|uniprotkb:B8ZZD6|uniprotkb:Q2XSU4|uniprotkb:Q8WV70|uniprotkb:Q2XSU3|uniprotkb:D6W5K4|uniprotkb:Q2M1K3|ensembl:ENSP00000377434|ensembl:ENSP00000386248|ensembl:ENSP00000386304|ensembl:ENSP00000387139 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:elmd3_human(display_long)|uniprotkb:ELMOD3(gene name)|psi-mi:ELMOD3(display_short)|uniprotkb:RBED1(gene name synonym)|uniprotkb:RBM29(gene name synonym)|uniprotkb:RNA-binding motif and ELMO domain-containing protein 1(gene name synonym)|uniprotkb:RNA-binding motif protein 29(gene name synonym)|uniprotkb:RNA-binding protein 29(gene name synonym)|uniprotkb:PP4068(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001128493.1|refseq:NP_001128494.1|refseq:NP_001128495.1|refseq:NP_001316720.1|refseq:NP_001316721.1|refseq:NP_001316722.1|ensembl:ENSG00000115459(gene)|ensembl:ENST00000393852(transcript)|ensembl:ENST00000409013(transcript)|ensembl:ENST00000409344(transcript)|ensembl:ENST00000409890(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0032420"(stereocilium)|go:"GO:0050790"(regulation of catalytic activity)|go:"GO:0060091"(kinocilium)|interpro:IPR006816(Engulfment and cell motility, ELM)|interpro:IPR030731 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NBG9o2J/ZXCN6vhBXDy9537PYFg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60664 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-725795|uniprotkb:Q53G77|uniprotkb:Q9BS03|uniprotkb:Q9UBD7|uniprotkb:Q9UP92|uniprotkb:A8K4Y9|intact:EBI-11103673|uniprotkb:K7EQF4|ensembl:ENSP00000221957 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:plin3_human(display_long)|uniprotkb:Cargo selection protein TIP47(gene name synonym)|uniprotkb:47 kDa mannose 6-phosphate receptor-binding protein(gene name synonym)|uniprotkb:Placental protein 17(gene name synonym)|uniprotkb:PLIN3(gene name)|psi-mi:PLIN3(display_short)|uniprotkb:TIP47(gene name synonym)|uniprotkb:M6PRBP1(gene name synonym)|uniprotkb:Mannose-6-phosphate receptor-binding protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001157666.1|refseq:NP_001157661.1|refseq:NP_005808.3|go:"GO:0016020"(membrane)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019915"(lipid storage)|go:"GO:0030133"(transport vesicle)|ensembl:ENSG00000105355(gene)|go:"GO:0045296"(cadherin binding)|interpro:IPR004279(Perilipin)|reactome:R-HSA-163560|reactome:R-HSA-6811440|reactome:R-HSA-9613354|ensembl:ENST00000221957(transcript)|reactome:R-HSA-9613829|reactome:R-HSA-9615710|reactome:R-HSA-9706019|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0010890"(positive regulation of sequestering of triglyceride) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:U+skqZ/oQtQscaEvfdh+AVnCCKA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15417 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2371691|uniprotkb:B4DFK6|uniprotkb:B4DP09|uniprotkb:F8WA86|uniprotkb:Q6FHA7|ensembl:ENSP00000359225 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cnn3_human(display_long)|uniprotkb:CNN3(gene name)|psi-mi:CNN3(display_short)|uniprotkb:Calponin, acidic isoform(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001830.1|refseq:NP_001272984.1|refseq:NP_001272985.1|refseq:XP_016855734.1|ensembl:ENSG00000117519(gene)|ensembl:ENST00000370206(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032780"(negative regulation of ATP-dependent activity)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR000557(Calponin repeat)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:UgeW769u9WgYLYNzTZ50xQqB5I09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P25685 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-357034|ensembl:ENSP00000254322|uniprotkb:B4DX52 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dnjb1_human(display_long)|uniprotkb:DNAJB1(gene name)|psi-mi:DNAJB1(display_short)|uniprotkb:DNAJ1(gene name synonym)|uniprotkb:HDJ1(gene name synonym)|uniprotkb:HSPF1(gene name synonym)|uniprotkb:Heat shock 40 kDa protein 1(gene name synonym)|uniprotkb:Human DnaJ protein 1(gene name synonym)|uniprotkb:DnaJ protein homolog 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N dip:DIP-41180N|ensembl:ENSG00000132002(gene)|ensembl:ENST00000254322(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001671"(ATPase activator activity)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0014069"(postsynaptic density)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0030900"(forebrain development)|go:"GO:0032781"(positive regulation of ATP-dependent activity)|refseq:NP_006136.1|refseq:XP_006722796.1|refseq:NP_001287843.1|refseq:NP_001300893.1|refseq:XP_011526258.1|refseq:XP_006722797.1|go:"GO:0043025"(neuronal cell body)|go:"GO:0043197"(dendritic spine)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045296"(cadherin binding)|go:"GO:0051082"(unfolded protein binding)|go:"GO:0051085"(chaperone cofactor-dependent protein refolding)|go:"GO:0051087"(chaperone binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0061827"(sperm head)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090084"(negative regulation of inclusion body assembly)|go:"GO:0097201"(negative regulation of transcription from RNA polymerase II promoter in response to stress)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900034"(regulation of cellular response to heat)|interpro:IPR001623(Heat shock protein DnaJ, N-terminal)|interpro:IPR002939(Chaperone DnaJ, C-terminal)|interpro:IPR018253|interpro:IPR036869|mint:P25685|rcsb pdb:1HDJ|rcsb pdb:2QLD|rcsb pdb:3AGX|rcsb pdb:3AGY|rcsb pdb:3AGZ|rcsb pdb:4WB7|rcsb pdb:6BYR|rcsb pdb:6WJF|rcsb pdb:6WJG|rcsb pdb:6Z5N|reactome:R-HSA-3371453|reactome:R-HSA-3371497|reactome:R-HSA-3371568|reactome:R-HSA-3371571|reactome:R-HSA-5687128|interpro:IPR008971(HSP40/DnaJ peptide-binding) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:8NJHM7hHFc+zqulNiUM9UMxT/ws9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13190 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-714206|uniprotkb:Q5U0D4|uniprotkb:Q7Z3T6|uniprotkb:Q9BUG1|uniprotkb:B2R8T2|ensembl:ENSP00000294179|uniprotkb:F8W8Q9 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stx5_human(display_long)|uniprotkb:STX5(gene name)|psi-mi:STX5(display_short)|uniprotkb:STX5A(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003155.2|ensembl:ENSG00000162236(gene)|ensembl:ENST00000294179(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000149"(SNARE binding)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006906"(vesicle fusion)|go:"GO:0012505"(endomembrane system)|go:"GO:0016021"(integral component of membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031982"(vesicle)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0034498"(early endosome to Golgi transport)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0045296"(cadherin binding)|go:"GO:0045732"(positive regulation of protein catabolic process)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0048278"(vesicle docking)|go:"GO:0048280"(vesicle fusion with Golgi apparatus)|go:"GO:0090166"(Golgi disassembly)|go:"GO:1903358"(regulation of Golgi organization)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR006012(Syntaxin/epimorphin, conserved site)|interpro:IPR010989(t-SNARE)|interpro:IPR021538|mint:Q13190|rcsb pdb:3EFO|reactome:R-HSA-204005|reactome:R-HSA-5694530|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013106|go:"GO:0012507"(ER to Golgi transport vesicle membrane)|reactome:R-HSA-9013408|reactome:R-HSA-9609523|refseq:NP_001231595.1|refseq:NP_001317223.1|dip:DIP-56987N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:cR4cS695ZWQQ5Bkim9HqmCE0hCE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q92522 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-876335|ensembl:ENSP00000329662 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:h1x_human(display_long)|uniprotkb:H1-10(gene name)|psi-mi:H1-10(display_short)|uniprotkb:H1FX(gene name synonym)|uniprotkb:Histone H1x(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000184897(gene)|ensembl:ENST00000333762(transcript)|go:"GO:0000786"(nucleosome)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0016584"(nucleosome positioning)|go:"GO:0030261"(chromosome condensation)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0031936"(obsolete negative regulation of chromatin silencing)|go:"GO:0045296"(cadherin binding)|go:"GO:0045910"(negative regulation of DNA recombination)|interpro:IPR005818(Histone H1/H5)|interpro:IPR005819(Histone H5)|interpro:IPR036388|interpro:IPR036390|mint:Q92522|refseq:NP_006017.1|dip:DIP-36358N|rcsb pdb:2LSO|rcsb pdb:6L9Z|rcsb pdb:7K60|rcsb pdb:7K63 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:T+NweCoHXj0rYsS6gJ4V42R9MpA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q92692 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-718419|uniprotkb:A8K5L5|uniprotkb:O75455|uniprotkb:Q96J29|uniprotkb:Q6IBI6|ensembl:ENSP00000252483 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nect2_human(display_long)|uniprotkb:NECTIN2(gene name)|psi-mi:NECTIN2(display_short)|uniprotkb:HVEB(gene name synonym)|uniprotkb:Herpes virus entry mediator B(gene name synonym)|uniprotkb:Nectin cell adhesion molecule 2(gene name synonym)|uniprotkb:PRR2(gene name synonym)|uniprotkb:PVRL2(gene name synonym)|uniprotkb:Poliovirus receptor-related protein 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001036189.1|refseq:NP_002847.1|ensembl:ENSG00000130202(gene)|ensembl:ENST00000252483(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001675"(acrosome assembly)|go:"GO:0002860"(positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target)|go:"GO:0002891"(positive regulation of immunoglobulin mediated immune response)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007286"(spermatid development)|go:"GO:0007289"(spermatid nucleus differentiation)|go:"GO:0009566"(fertilization)|go:"GO:0009986"(cell surface)|go:"GO:0015026"(coreceptor activity)|go:"GO:0016021"(integral component of membrane)|go:"GO:0019064"(fusion of virus membrane with host plasma membrane)|go:"GO:0030382"(sperm mitochondrion organization)|go:"GO:0032990"(cell part morphogenesis)|go:"GO:0033005"(positive regulation of mast cell activation)|go:"GO:0042271"(susceptibility to natural killer cell mediated cytotoxicity)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044406"(adhesion of symbiont to host)|go:"GO:0044782"(cilium organization)|go:"GO:0045954"(positive regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046596"(regulation of viral entry into host cell)|go:"GO:0046814"(coreceptor-mediated virion attachment to host cell)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051654"(establishment of mitochondrion localization)|go:"GO:0060370"(susceptibility to T cell mediated cytotoxicity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR003599(Immunoglobulin subtype)|interpro:IPR007110(Immunoglobulin-like)|interpro:IPR013106(Immunoglobulin V-set)|interpro:IPR013162(CD80-like, immunoglobulin C2-set)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR033318|interpro:IPR036179|rcsb pdb:3R0N|rcsb pdb:4DFH|rcsb pdb:4DFI|rcsb pdb:4HZA|rcsb pdb:5V52|reactome:R-HSA-198933|reactome:R-HSA-418990|reactome:R-HSA-420597|go:"GO:0042803"(protein homodimerization activity)|dip:DIP-41043N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xGLJch8JXc+urj11GXKFPgBLYuc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P61313 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-443462|ensembl:ENSP00000309334|ensembl:ENSP00000346867|ensembl:ENSP00000388529|ensembl:ENSP00000416692|ensembl:ENSP00000483260|ensembl:ENSP00000493759|uniprotkb:Q642I1|uniprotkb:Q9H2E5|uniprotkb:P39030|uniprotkb:P41051|uniprotkb:Q6IPX6|uniprotkb:Q8WYP2|uniprotkb:Q96C44|uniprotkb:Q5U0C0|intact:EBI-2877712 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl15_human(display_long)|uniprotkb:RPL15(gene name)|psi-mi:RPL15(display_short)|uniprotkb:EC45(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL15(gene name synonym)|uniprotkb:TCBAP0781(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000174748(gene)|ensembl:ENST00000307839(transcript)|ensembl:ENST00000354811(transcript)|ensembl:ENST00000413699(transcript)|ensembl:ENST00000415719(transcript)|ensembl:ENST00000611050(transcript)|ensembl:ENST00000644185(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031672"(A band)|go:"GO:0045296"(cadherin binding)|go:"GO:0045471"(response to ethanol)|interpro:IPR000439(Ribosomal protein L15e)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR020925|interpro:IPR024794|mint:P61313|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_002939.2|refseq:NP_001240308.1|refseq:NP_001240309.1|refseq:NP_001240311.1|refseq:NP_001240312.1|refseq:NP_001240313.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:wllGpJicgC5uwkZV6e4QRwDcrBo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15599 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1149760|uniprotkb:O00272|uniprotkb:O00556|uniprotkb:Q3KQY7|uniprotkb:D3DU84|uniprotkb:D3DU85|uniprotkb:H3BSV6|ensembl:ENSP00000408005|intact:EBI-15579694 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:nhrf2_human(display_long)|uniprotkb:SLC9A3R2(gene name)|psi-mi:SLC9A3R2(display_short)|uniprotkb:NHERF2(gene name synonym)|uniprotkb:Tyrosine kinase activator protein 1(gene name synonym)|uniprotkb:SRY-interacting protein 1(gene name synonym)|uniprotkb:Solute carrier family 9 isoform A3 regulatory factor 2(gene name synonym)|uniprotkb:NHE3 kinase A regulatory protein E3KARP(gene name synonym)|uniprotkb:Sodium-hydrogen exchanger regulatory factor 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001123484.1|refseq:NP_004776.3|refseq:NP_001239002.1|ensembl:ENSG00000065054(gene)|ensembl:ENST00000424542(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0012505"(endomembrane system)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019902"(phosphatase binding)|go:"GO:0031799"(type 2 metabotropic glutamate receptor binding)|go:"GO:0031800"(type 3 metabotropic glutamate receptor binding)|go:"GO:0043495"(protein-membrane adaptor activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR015098(EBP50, C-terminal)|interpro:IPR017300("Na(+)/H(+) exchange regulatory cofactor NHE-RF")|interpro:IPR031197|interpro:IPR036034|mint:Q15599|rcsb pdb:2D11|rcsb pdb:2HE4|rcsb pdb:2OCS|rcsb pdb:4P0C|go:"GO:0042802"(identical protein binding)|dip:DIP-29093N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:BRqFx6BigKEZV84KUdfvppEXg+s9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P49327 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-356658|uniprotkb:Q4LE83|uniprotkb:Q13479|uniprotkb:Q16702|uniprotkb:Q6P4U5|uniprotkb:Q6SS02|uniprotkb:Q969R1|uniprotkb:Q96C68|uniprotkb:Q96IT0|ensembl:ENSP00000304592 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:fas_human(display_long)|uniprotkb:FASN(gene name)|psi-mi:FASN(display_short)|uniprotkb:FAS(gene name synonym)|uniprotkb:Type I fatty acid synthase(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004095.4|ensembl:ENSG00000169710(gene)|ensembl:ENST00000306749(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0002068"(glandular epithelial cell development)|go:"GO:0003723"(RNA binding)|go:"GO:0004313"([acyl-carrier-protein] S-acetyltransferase activity)|go:"GO:0004314"([acyl-carrier-protein] S-malonyltransferase activity)|go:"GO:0004315"(3-oxoacyl-[acyl-carrier-protein] synthase activity)|go:"GO:0004316"("3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity")|go:"GO:0004317"(3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0004320"(oleoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006084"(acetyl-CoA metabolic process)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0006633"(fatty acid biosynthetic process)|go:"GO:0008611"(ether lipid biosynthetic process)|go:"GO:0008659"("(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity")|go:"GO:0008693"(3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0016020"(membrane)|go:"GO:0016295"(myristoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0016296"(palmitoyl-[acyl-carrier-protein] hydrolase activity)|go:"GO:0030223"(neutrophil differentiation)|go:"GO:0030224"(monocyte differentiation)|go:"GO:0030879"(mammary gland development)|go:"GO:0031177"(phosphopantetheine binding)|go:"GO:0042470"(melanosome)|go:"GO:0042587"(glycogen granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0047451"(3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0102131"(obsolete 3-oxo-glutaryl-[acp] methyl ester reductase activity)|go:"GO:0102132"(obsolete 3-oxo-pimeloyl-[acp] methyl ester reductase activity)|interpro:IPR001031(Thioesterase)|interpro:IPR001227(Acyl transferase region)|interpro:IPR006162(Phosphopantetheine attachment site)|interpro:IPR009081(Acyl carrier protein-like)|interpro:IPR011032(GroES-like)|interpro:IPR013149(Alcohol dehydrogenase, zinc-binding)|interpro:IPR013217(Methyltransferase type 12)|interpro:IPR013968(Polyketide synthase, KR)|interpro:IPR014030(Beta-ketoacyl synthase, N-terminal)|interpro:IPR014031(Beta-ketoacyl synthase, C-terminal)|interpro:IPR014043(Acyl transferase)|interpro:IPR016035(Acyl transferase/acyl hydrolase/lysophospholipase)|interpro:IPR016036(Malonyl-CoA ACP transacylase, ACP-binding)|interpro:IPR016039(Thiolase-like)|interpro:IPR018201|interpro:IPR020806|interpro:IPR020807|interpro:IPR020841|interpro:IPR020843|interpro:IPR029058|interpro:IPR029063|interpro:IPR032821|interpro:IPR036291|interpro:IPR036736|interpro:IPR042104|mint:P49327|rcsb pdb:1XKT|rcsb pdb:2CG5|rcsb pdb:2JFD|rcsb pdb:2JFK|rcsb pdb:2PX6|rcsb pdb:3HHD|rcsb pdb:3TJM|rcsb pdb:4PIV|rcsb pdb:4W82|rcsb pdb:4W9N|rcsb pdb:4Z49|rcsb pdb:5C37|rcsb pdb:6NNA|reactome:R-HSA-163765|reactome:R-HSA-199220|reactome:R-HSA-2426168|reactome:R-HSA-75105|reactome:R-HSA-9029558|go:"GO:0047117"("enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity")|refseq:XP_011521840.1|dip:DIP-33681N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:bQYEH/uQ6l+SPzLBDNCV5yP+yzs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IUW5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11343385|uniprotkb:Q8NBK1|ensembl:ENSP00000313385|ensembl:ENSP00000398778 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rell1_human(display_long)|uniprotkb:RELL1(gene name)|psi-mi:RELL1(display_short)|uniprotkb:PSEC0162(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001078868.1|refseq:NP_001078869.1|ensembl:ENSG00000181826(gene)|ensembl:ENST00000454158(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:1900745"(positive regulation of p38MAPK cascade)|interpro:IPR022248|interpro:IPR042315|ensembl:ENST00000314117(transcript) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:in0yR+RiPdt1RmVWn5x9ad0kcws9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P07476 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11307220|uniprotkb:Q5T7P4|intact:EBI-28974501|ensembl:ENSP00000357753 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:invo_human(display_long)|uniprotkb:IVL(gene name)|psi-mi:IVL(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000357753|refseq:NP_005538.2|ensembl:ENSG00000163207(gene)|ensembl:ENST00000368764(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0010224"(response to UV-B)|go:"GO:0016604"(nuclear body)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0018153"("isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine")|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000354(Involucrin repeat)|interpro:IPR002360(Involucrin)|interpro:IPR019571|interpro:IPR019743|mint:P07476|rcsb pdb:1EU0|reactome:R-HSA-6809371 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:1ZHgB7J+AXcC45RMlCMkoEwUta49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NZZ3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-751303|uniprotkb:Q5VXW2|uniprotkb:Q96AV2|uniprotkb:Q9HB68|uniprotkb:Q9NYS4|uniprotkb:Q9Y323|uniprotkb:B4DIR6|uniprotkb:B2RD95|ensembl:ENSP00000223500 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:chmp5_human(display_long)|uniprotkb:Chromatin-modifying protein 5(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 60(gene name synonym)|uniprotkb:SNF7 domain-containing protein 2(gene name synonym)|uniprotkb:CHMP5(gene name)|psi-mi:CHMP5(display_short)|uniprotkb:C9orf83(gene name synonym)|uniprotkb:SNF7DC2(gene name synonym)|uniprotkb:CGI-34(orf name)|uniprotkb:HSPC177(orf name)|uniprotkb:PNAS-2(orf name)|uniprotkb:PNAS-114(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_057494.3|refseq:NP_001182465.1|dip:DIP-50420N|ensembl:ENSG00000086065(gene)|ensembl:ENST00000223500(transcript)|go:"GO:0001919"(regulation of receptor recycling)|go:"GO:0005634"(nucleus)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006900"(vesicle budding from membrane)|go:"GO:0006997"(nucleus organization)|go:"GO:0007040"(lysosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0008333"(endosome to lysosome transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010824"(regulation of centrosome duplication)|go:"GO:0015031"(protein transport)|go:"GO:0032511"(late endosome to vacuole transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0045296"(cadherin binding)|go:"GO:0046755"(viral budding)|go:"GO:0061952"(midbody abscission)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0071225"(cellular response to muramyl dipeptide)|go:"GO:0071985"(multivesicular body sorting pathway)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|mint:Q9NZZ3|rcsb pdb:2LXM|rcsb pdb:3ULY|rcsb pdb:3UM0|rcsb pdb:3UM1|rcsb pdb:3UM2|rcsb pdb:4TXR|reactome:R-HSA-162588|reactome:R-HSA-917729 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:VqeFh9Sg3XIfJuZBF59GgMgY53c9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UBC2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2556746|intact:EBI-28972990|ensembl:ENSP00000248070|uniprotkb:B4DKA3|uniprotkb:A2RRF3|uniprotkb:A5PL29 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ep15r_human(display_long)|uniprotkb:EPS15R(gene name synonym)|uniprotkb:Eps15-related protein(gene name synonym)|uniprotkb:EPS15L1(gene name)|psi-mi:EPS15L1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_067058.1|ensembl:ENSP00000248070|ensembl:ENST00000455140|ensembl:ENSP00000393313|ensembl:ENST00000535753|ensembl:ENSP00000440103|ensembl:ENST00000597937|ensembl:ENSP00000472267|ensembl:ENST00000602022|ensembl:ENSP00000471981|ensembl:ENSG00000127527(gene)|ensembl:ENST00000248070(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0016197"(endosomal transport)|go:"GO:0045296"(cadherin binding)|interpro:IPR000261("EPS15 homology (EH)")|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR018247|mint:Q9UBC2|reactome:R-HSA-182971|reactome:R-HSA-8856825|reactome:R-HSA-8856828|go:"GO:0030132"(clathrin coat of coated pit)|refseq:NP_001245303.1|refseq:NP_001245304.1|refseq:NP_001245305.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6Bsao5czetxRxIiy3O/rZox4U+Y9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P25815 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-743700|uniprotkb:Q5J7W2|ensembl:ENSP00000296370 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:s100p_human(display_long)|uniprotkb:S100 calcium-binding protein P(gene name synonym)|uniprotkb:S100P(gene name)|psi-mi:S100P(display_short)|uniprotkb:S100E(gene name synonym)|uniprotkb:Protein S100-E(gene name synonym)|uniprotkb:Migration-inducing gene 9 protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005971.1|ensembl:ENSG00000163993(gene)|ensembl:ENST00000296370(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0010033"(response to organic substance)|go:"GO:0031528"(microvillus membrane)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043542"(endothelial cell migration)|go:"GO:0045296"(cadherin binding)|go:"GO:0046914"(transition metal ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR034325|rcsb pdb:1J55|rcsb pdb:1OZO|rcsb pdb:2MJW|reactome:R-HSA-6798695|interpro:IPR011992(EF-Hand type) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:wuvwIPFST5gUGqRSJmkUw+CbJv49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q1W6H9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3942563|ensembl:ENSP00000328347 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:f110c_human(display_long)|uniprotkb:FAM110C(gene name)|psi-mi:FAM110C(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001071178.2|ensembl:ENSG00000184731(gene)|ensembl:ENST00000327669(transcript)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005874"(microtubule)|go:"GO:0005938"(cell cortex)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0043014"(alpha-tubulin binding)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0060491"(regulation of cell projection assembly)|interpro:IPR025739|interpro:IPR025740|interpro:IPR025741 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:GPheuY5vQYCJo9dLLhhb4+66Myk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q99618 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-739534|uniprotkb:A8K5V6|uniprotkb:D3DUS6|ensembl:ENSP00000442068|ensembl:ENSP00000446339 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cdca3_human(display_long)|uniprotkb:CDCA3(gene name)|psi-mi:CDCA3(display_short)|uniprotkb:Trigger of mitotic entry protein 1(gene name synonym)|uniprotkb:Gene-rich cluster protein C8(gene name synonym)|uniprotkb:C8(gene name synonym)|uniprotkb:GRCC8(gene name synonym)|uniprotkb:TOME1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001284532.1|refseq:NP_001284533.1|refseq:NP_112589.1|ensembl:ENST00000535406(transcript)|ensembl:ENST00000538862(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0016567"(protein ubiquitination)|go:"GO:0051301"(cell division)|interpro:IPR038832|ensembl:ENSG00000111665(gene)|refseq:NP_001317948.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:UmhACVP83jo9/xqP7qDSSvKgiAo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P46939 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-295856|intact:EBI-784141|uniprotkb:Q5SZ57|uniprotkb:Q5SYY1|uniprotkb:Q9UJ40|ensembl:ENSP00000356515 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:utrn_human(display_long)|uniprotkb:UTRN(gene name)|psi-mi:UTRN(display_short)|uniprotkb:DMDL(gene name synonym)|uniprotkb:Dystrophin-related protein 1(gene name synonym)|uniprotkb:DRP1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000356515|refseq:XP_011534408.1|refseq:NP_009055.2|refseq:XP_005267187.1|dip:DIP-711N|ensembl:ENSG00000152818(gene)|ensembl:ENST00000367545(transcript)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0003779"(actin binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0006936"(muscle contraction)|go:"GO:0007517"(muscle organ development)|go:"GO:0008270"(zinc ion binding)|go:"GO:0016010"(dystrophin-associated glycoprotein complex)|go:"GO:0016020"(membrane)|go:"GO:0017166"(vinculin binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030175"(filopodium)|go:"GO:0031527"(filopodium membrane)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042383"(sarcolemma)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000649"(regulation of sodium ion transmembrane transporter activity)|interpro:IPR000433(Zinc finger, ZZ-type)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR002017(Spectrin repeat)|interpro:IPR011992(EF-Hand type)|interpro:IPR015153(EF-hand, region 1)|interpro:IPR015154(EF-hand, region 2)|interpro:IPR018159|interpro:IPR035436|interpro:IPR036020|interpro:IPR036872|interpro:IPR043145|mint:P46939|rcsb pdb:1BHD|rcsb pdb:1QAG|rcsb pdb:6M5G|reactome:R-HSA-9619665 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:metWqbqGtzonNZ1mgNjlFrenuI89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8WUF5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-5550163|uniprotkb:Q2PNZ9|uniprotkb:Q5DU71|uniprotkb:Q5I1X4|uniprotkb:Q6P1R7|uniprotkb:Q6PKF8|uniprotkb:Q9Y290|ensembl:ENSP00000354218|ensembl:ENSP00000403902 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:iaspp_human(display_long)|uniprotkb:PPP1R13L(gene name)|psi-mi:PPP1R13L(display_short)|uniprotkb:IASPP(gene name synonym)|uniprotkb:NKIP1(gene name synonym)|uniprotkb:PPP1R13BL(gene name synonym)|uniprotkb:RAI(gene name synonym)|uniprotkb:Inhibitor of ASPP protein(gene name synonym)|uniprotkb:NFkB-interacting protein 1(gene name synonym)|uniprotkb:PPP1R13B-like protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001135974.1|refseq:NP_006654.2|refseq:XP_016881666.1|refseq:XP_016881667.1|dip:DIP-29586N|ensembl:ENSG00000104881(gene)|ensembl:ENST00000360957(transcript)|ensembl:ENST00000418234(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0003215"(cardiac right ventricle morphogenesis)|go:"GO:0003229"(ventricular cardiac muscle tissue development)|go:"GO:0003714"(transcription corepressor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006351"(transcription, DNA-templated)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006915"(apoptotic process)|go:"GO:0008134"(transcription factor binding)|go:"GO:0009791"(post-embryonic development)|go:"GO:0030054"(cell junction)|go:"GO:0031076"(embryonic camera-type eye development)|go:"GO:0035264"(multicellular organism growth)|go:"GO:0042633"(hair cycle)|go:"GO:0042802"(identical protein binding)|go:"GO:0045171"(intercellular bridge)|go:"GO:0045296"(cadherin binding)|go:"GO:0045597"(positive regulation of cell differentiation)|go:"GO:0048871"(multicellular organismal homeostasis)|go:"GO:0060048"(cardiac muscle contraction)|interpro:IPR001452(Src homology-3)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR028320|interpro:IPR036028|interpro:IPR036770|interpro:IPR042722|mint:Q8WUF5|rcsb pdb:2VGE|rcsb pdb:6DCX|rcsb pdb:6HL6|rcsb pdb:6RZ3|reactome:R-HSA-6804759 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0MfBf9sG2+pc4Isd+GDCBm6b9Eo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7Z2K8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11152848|uniprotkb:Q96PZ4|uniprotkb:Q8ND74|uniprotkb:C9JM70|ensembl:ENSP00000305839 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:grin1_human(display_long)|uniprotkb:GPRIN1(gene name)|psi-mi:GPRIN1(display_short)|uniprotkb:KIAA1893(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_443131.2|ensembl:ENSG00000169258(gene)|ensembl:ENST00000303991(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0030426"(growth cone)|go:"GO:0051219"(phosphoprotein binding)|interpro:IPR026646|interpro:IPR032745|reactome:R-HSA-9022699|go:"GO:0031175"(neuron projection development) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:jrKC+dySA+Jej1vv29IWm01SUsY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NRY6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-750734|uniprotkb:Q567U0|uniprotkb:Q8NBW6|uniprotkb:Q96F13|uniprotkb:A8K252|ensembl:ENSP00000316021|ensembl:ENSP00000459019|ensembl:ENSP00000459419|ensembl:ENSP00000491350|ensembl:ENSP00000491393|ensembl:ENSP00000492026|ensembl:ENSP00000492083|ensembl:ENSP00000483743 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pls3_human(display_long)|uniprotkb:"Ca(2+)-dependent phospholipid scramblase 3"(gene name synonym)|uniprotkb:PLSCR3(gene name)|psi-mi:PLSCR3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001188505.1|refseq:NP_065093.2|ensembl:ENSG00000187838(gene)|ensembl:ENSG00000284009(gene)|ensembl:ENST00000324822(transcript)|ensembl:ENST00000574401(transcript)|ensembl:ENST00000576201(transcript)|ensembl:ENST00000619711(transcript)|ensembl:ENST00000639780(transcript)|ensembl:ENST00000639874(transcript)|ensembl:ENST00000640053(transcript)|ensembl:ENST00000640375(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006915"(apoptotic process)|go:"GO:0016021"(integral component of membrane)|go:"GO:0017121"(plasma membrane phospholipid scrambling)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0017128"(phospholipid scramblase activity)|go:"GO:0032049"(cardiolipin biosynthetic process)|go:"GO:0032791"(lead ion binding)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043621"(protein self-association)|go:"GO:0045340"(mercury ion binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0071222"(cellular response to lipopolysaccharide)|go:"GO:0090199"(regulation of release of cytochrome c from mitochondria)|interpro:IPR005552(Scramblase) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:JKzacFCwrCQpcI3EJsLvpAbLFCA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15365 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q92597 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-716486|uniprotkb:O15207|uniprotkb:Q9NYR6|uniprotkb:Q9UK29|uniprotkb:Q6IBG2|uniprotkb:B3KR80|uniprotkb:B7Z446|ensembl:ENSP00000319977|ensembl:ENSP00000404854 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ndrg1_human(display_long)|uniprotkb:N-myc downstream-regulated gene 1 protein(gene name synonym)|uniprotkb:Differentiation-related gene 1 protein(gene name synonym)|uniprotkb:Reducing agents and tunicamycin-responsive protein(gene name synonym)|uniprotkb:Nickel-specific induction protein Cap43(gene name synonym)|uniprotkb:Rit42(gene name synonym)|uniprotkb:NDRG1(gene name)|psi-mi:NDRG1(display_short)|uniprotkb:CAP43(gene name synonym)|uniprotkb:DRG1(gene name synonym)|uniprotkb:RTP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001128714.1|refseq:NP_006087.2|refseq:NP_001245361.1|refseq:NP_001245362.1|ensembl:ENSG00000104419(gene)|ensembl:ENST00000323851(transcript)|ensembl:ENST00000414097(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008017"(microtubule binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010038"(response to metal ion)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0030330"(DNA damage response, signal transduction by p53 class mediator)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032287"(peripheral nervous system myelin maintenance)|go:"GO:0043015"(gamma-tubulin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045576"(mast cell activation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0055038"(recycling endosome membrane)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071456"(cellular response to hypoxia)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099173"(postsynapse organization)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030693|rcsb pdb:6ZMM|reactome:R-HSA-6803205 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:zeyNRbcgqPcHXkqwE42s1e9uEqI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P37802 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1056740|intact:EBI-2825986|uniprotkb:Q5JRQ6|uniprotkb:Q5JRQ7|uniprotkb:Q9BUH5|uniprotkb:Q9H4P0|uniprotkb:Q6FGI1|uniprotkb:E9KL39|ensembl:ENSP00000357075|ensembl:ENSP00000357077 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tagl2_human(display_long)|uniprotkb:TAGLN2(gene name)|psi-mi:TAGLN2(display_short)|uniprotkb:KIAA0120(gene name synonym)|uniprotkb:SM22-alpha homolog(gene name synonym)|uniprotkb:CDABP0035(orf name)|uniprotkb:Epididymis tissue protein Li 7e(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003555.1|refseq:NP_001264152.1|refseq:NP_001264153.1|ensembl:ENSG00000158710(gene)|ensembl:ENST00000320307(transcript)|ensembl:ENST00000368097(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0030855"(epithelial cell differentiation)|go:"GO:0031982"(vesicle)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000557(Calponin repeat)|interpro:IPR001061("Transgelin (SM22-alpha)")|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR003096(SM22/calponin)|interpro:IPR036872|mint:P37802|rcsb pdb:1WYM|reactome:R-HSA-114608 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:JxbMK5SbZWQd+XA9iYc/xuNaVQc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P04083 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-354007|ensembl:ENSP00000257497|ensembl:ENSP00000366109|uniprotkb:B5BU38 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:anxa1_human(display_long)|uniprotkb:ANXA1(gene name)|psi-mi:ANXA1(display_short)|uniprotkb:ANX1(gene name synonym)|uniprotkb:LPC1(gene name synonym)|uniprotkb:Annexin-1(gene name synonym)|uniprotkb:Annexin I(gene name synonym)|uniprotkb:Lipocortin I(gene name synonym)|uniprotkb:Calpactin II(gene name synonym)|uniprotkb:Chromobindin-9(gene name synonym)|uniprotkb:p35(gene name synonym)|uniprotkb:Phospholipase A2 inhibitory protein(gene name synonym)|uniprotkb:Calpactin-2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000691.1|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019834"(phospholipase A2 inhibitor activity)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0030073"(insulin secretion)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0030850"(prostate gland development)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031232"(extrinsic component of external side of plasma membrane)|go:"GO:0031313"(extrinsic component of endosome membrane)|go:"GO:0031340"(positive regulation of vesicle fusion)|go:"GO:0031394"(positive regulation of prostaglandin biosynthetic process)|go:"GO:0031514"(motile cilium)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031966"(mitochondrial membrane)|go:"GO:0031982"(vesicle)|go:"GO:0032355"(response to estradiol)|go:"GO:0032508"(DNA duplex unwinding)|go:"GO:0032652"(regulation of interleukin-1 production)|go:"GO:0032717"(negative regulation of interleukin-8 production)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033031"(positive regulation of neutrophil apoptotic process)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0036121"(double-stranded DNA helicase activity)|go:"GO:0042063"(gliogenesis)|go:"GO:0042102"(positive regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042493"|go:"GO:0042629"(mast cell granule)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043434"(response to peptide hormone)|go:"GO:0045087"(innate immune response)|go:"GO:0045627"(positive regulation of T-helper 1 cell differentiation)|go:"GO:0045629"(negative regulation of T-helper 2 cell differentiation)|go:"GO:0045920"(negative regulation of exocytosis)|go:"GO:0046632"(alpha-beta T cell differentiation)|ensembl:ENSG00000135046(gene)|ensembl:ENST00000257497(transcript)|ensembl:ENST00000376911(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001780"(neutrophil homeostasis)|go:"GO:0001891"(phagocytic cup)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002548"(monocyte chemotaxis)|go:"GO:0002685"(regulation of leukocyte migration)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003727"(single-stranded RNA binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005544"(calcium-dependent phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006909"(phagocytosis)|go:"GO:0006954"(inflammatory response)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007187"(G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009986"(cell surface)|go:"GO:0010165"(response to X-ray)|go:"GO:0014839"(myoblast migration involved in skeletal muscle regeneration)|go:"GO:0016323"(basolateral plasma membrane)|refseq:XP_011516911.1|dip:DIP-32875N|go:"GO:0046883"(regulation of hormone secretion)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070301"(cellular response to hydrogen peroxide)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0070459"(prolactin secretion)|go:"GO:0070555"(response to interleukin-1)|go:"GO:0071385"(cellular response to glucocorticoid stimulus)|go:"GO:0071621"(granulocyte chemotaxis)|go:"GO:0090050"(positive regulation of cell migration involved in sprouting angiogenesis)|go:"GO:0090303"(positive regulation of wound healing)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097350"(neutrophil clearance)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1900138"(negative regulation of phospholipase A2 activity)|go:"GO:1990814"(DNA/DNA annealing activity)|interpro:IPR001464(Annexin)|interpro:IPR002388(Annexin, type I)|interpro:IPR018252|interpro:IPR018502|interpro:IPR037104|mint:P04083|rcsb pdb:1AIN|rcsb pdb:1BO9|rcsb pdb:1QLS|rcsb pdb:5VFW|reactome:R-HSA-416476|reactome:R-HSA-418594|reactome:R-HSA-444473|reactome:R-HSA-445355|reactome:R-HSA-6785807|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0050482"(arachidonic acid secretion)|go:"GO:0050709"(negative regulation of protein secretion)|go:"GO:0050727"(regulation of inflammatory response) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:QKmqz+UsAof35B/so2qKLQjn2v09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y490 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2462036|uniprotkb:A6NMY0|uniprotkb:Q86YD0|uniprotkb:Q9NZQ2|uniprotkb:Q9UHH8|uniprotkb:Q9UPX3|intact:EBI-28967697|ensembl:ENSP00000316029 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:tln1_human(display_long)|uniprotkb:TLN1(gene name)|psi-mi:TLN1(display_short)|uniprotkb:KIAA1027(gene name synonym)|uniprotkb:TLN(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000316029|refseq:NP_006280.3|ensembl:ENSG00000137076(gene)|ensembl:ENST00000314888(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0001786"(phosphatidylserine binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009986"(cell surface)|go:"GO:0017166"(vinculin binding)|go:"GO:0030274"(LIM domain binding)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0032587"(ruffle membrane)|go:"GO:0033622"(integrin activation)|go:"GO:0035091"(phosphatidylinositol binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0098609"(cell-cell adhesion)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR002558(I/LWEQ)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR015009(Vinculin Binding Site)|interpro:IPR015224(Talin, central)|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR032425|interpro:IPR035963|interpro:IPR035964|interpro:IPR036476|interpro:IPR036723|interpro:IPR037438|mint:Q9Y490|rcsb pdb:1SYQ|rcsb pdb:2MWN|rcsb pdb:4DJ9|rcsb pdb:6R9T|reactome:R-HSA-114608|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381038|reactome:R-HSA-399955|reactome:R-HSA-445355|reactome:R-HSA-5674135|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:C7FGaR2291KB6hBSloee5L8lYgA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UQB8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-525456|uniprotkb:O43858|uniprotkb:Q53HB1|uniprotkb:Q86WC1|uniprotkb:Q8N5C0|uniprotkb:Q96CR7|uniprotkb:Q9UBR3|uniprotkb:Q9UQ43|ensembl:ENSP00000316338 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:baip2_human(display_long)|uniprotkb:Insulin receptor substrate protein of 53 kDa(gene name synonym)|uniprotkb:Insulin receptor substrate p53/p58(gene name synonym)|uniprotkb:Fas ligand-associated factor 3(gene name synonym)|uniprotkb:BAIAP2(gene name)|psi-mi:BAIAP2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001138360.1|refseq:NP_006331.1|refseq:NP_059344.1|refseq:NP_059345.1|refseq:XP_005257005.1|dip:DIP-29272N|go:"GO:0009617"(response to bacterium)|go:"GO:0016358"(dendrite development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030141"(secretory granule)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030175"(filopodium)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0035418"(protein localization to synapse)|go:"GO:0042802"(identical protein binding)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043198"(dendritic shaft)|go:"GO:0044306"(neuron projection terminus)|go:"GO:0048167"(regulation of synaptic plasticity)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060076"(excitatory synapse)|go:"GO:0061003"(positive regulation of dendritic spine morphogenesis)|go:"GO:0061845"(neuron projection branch point)|go:"GO:0061846"(dendritic spine cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070064"(proline-rich region binding)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0099523"(presynaptic cytosol)|go:"GO:0099524"(postsynaptic cytosol)|go:"GO:0099564"(modification of synaptic structure, modulating synaptic transmission)|go:"GO:1905232"(cellular response to L-glutamate)|go:"GO:1905274"(regulation of modification of postsynaptic actin cytoskeleton)|go:"GO:2000251"(positive regulation of actin cytoskeleton reorganization)|go:"GO:2000463"(positive regulation of excitatory postsynaptic potential)|interpro:IPR001452(Src homology-3)|interpro:IPR013606("IRSp53/MIM homology domain (IMD)")|interpro:IPR027267|interpro:IPR027681|interpro:IPR030128|interpro:IPR035594|interpro:IPR036028|mint:Q9UQB8|rcsb pdb:1WDZ|rcsb pdb:1Y2O|rcsb pdb:2YKT|rcsb pdb:3RNJ|rcsb pdb:4JS0|rcsb pdb:6BCR|rcsb pdb:6BCY|rcsb pdb:6BD1|rcsb pdb:6BD2|rcsb pdb:6BQT|rcsb pdb:6ZEG|rcsb pdb:6ZEI|reactome:R-HSA-2029482|reactome:R-HSA-4420097|reactome:R-HSA-5663213|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013423|reactome:R-HSA-9664422|ensembl:ENSG00000175866(gene)|ensembl:ENST00000321300(transcript)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001726"(ruffle)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007409"(axonogenesis)|go:"GO:0007420"(brain development)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0008286"(insulin receptor signaling pathway)|go:"GO:0008360"(regulation of cell shape) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:BRbjAYBnAJN0Pzb7bc/Qtb4w5bY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9P206 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3939668|uniprotkb:B5MDY0|uniprotkb:Q8TCQ0|ensembl:ENSP00000362579|uniprotkb:B4DQU8|uniprotkb:C9JH84 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:k1522_human(display_long)|uniprotkb:KIAA1522(gene name)|psi-mi:KIAA1522(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000294521|ensembl:ENSP00000294521|ensembl:ENSP00000362579|ensembl:ENST00000373481|ensembl:ENSP00000362580|ensembl:ENST00000401073|ensembl:ENSP00000383851|ensembl:ENSG00000162522(gene)|ensembl:ENST00000373480(transcript)|go:"GO:0030154"(cell differentiation)|mint:Q9P206|refseq:NP_001185901.1|refseq:NP_001185902.1|refseq:NP_065939.2|refseq:XP_006710854.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RbEPBXAGgG4Icbw8i4pFoIKU1LM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P49207 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1051893|uniprotkb:Q6FG66|uniprotkb:Q9BUZ2|ensembl:ENSP00000378160|ensembl:ENSP00000378162|ensembl:ENSP00000378163|ensembl:ENSP00000423316|ensembl:ENSP00000423983 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl34_human(display_long)|uniprotkb:RPL34(gene name)|psi-mi:RPL34(display_short)|uniprotkb:Large ribosomal subunit protein eL34(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000986.2|refseq:NP_296374.1|refseq:NP_001306161.1|refseq:NP_001306163.1|refseq:NP_001306164.1|refseq:NP_001306165.1|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|rcsb pdb:6Y6X|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR008195(Ribosomal protein L34e)|interpro:IPR018065|mint:P49207|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|ensembl:ENSG00000109475(gene)|ensembl:ENST00000394665(transcript)|ensembl:ENST00000394667(transcript)|ensembl:ENST00000394668(transcript)|ensembl:ENST00000502534(transcript)|ensembl:ENST00000506397(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:NSGnIE6uSimeraPQ7ZZ+xRugABg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P06733 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353877|uniprotkb:P22712|uniprotkb:Q16704|uniprotkb:Q4TUS4|uniprotkb:Q658M5|uniprotkb:Q6GMP2|uniprotkb:Q71V37|uniprotkb:Q7Z3V6|uniprotkb:Q8WU71|uniprotkb:Q96GV1|uniprotkb:Q9BT62|uniprotkb:Q9UM55|ensembl:ENSP00000234590|uniprotkb:B2RD59|uniprotkb:Q53FT9|uniprotkb:Q53HR3|uniprotkb:Q9UCH6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:enoa_human(display_long)|uniprotkb:ENO1(gene name)|psi-mi:ENO1(display_short)|uniprotkb:ENO1L1(gene name synonym)|uniprotkb:MBPB1(gene name synonym)|uniprotkb:MPB1(gene name synonym)|uniprotkb:2-phospho-D-glycerate hydro-lyase(gene name synonym)|uniprotkb:Non-neural enolase(gene name synonym)|uniprotkb:Enolase 1(gene name synonym)|uniprotkb:Phosphopyruvate hydratase(gene name synonym)|uniprotkb:C-myc promoter-binding protein(gene name synonym)|uniprotkb:MBP-1(gene name synonym)|uniprotkb:MPB-1(gene name synonym)|uniprotkb:Plasminogen-binding protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001188412.1|refseq:NP_001419.1|ensembl:ENSG00000074800(gene)|ensembl:ENST00000234590(transcript)|go:"GO:0000015"(phosphopyruvate hydratase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001227"(DNA-binding transcription repressor activity, RNA polymerase II-specific)|go:"GO:0003723"(RNA binding)|go:"GO:0004634"(phosphopyruvate hydratase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006096"(glycolytic process)|go:"GO:0009615"(response to virus)|go:"GO:0009986"(cell surface)|go:"GO:0010756"(positive regulation of plasminogen activation)|go:"GO:0016020"(membrane)|go:"GO:0030308"(negative regulation of cell growth)|go:"GO:0031430"(M band)|go:"GO:0032889"(regulation of vacuole fusion, non-autophagic)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045933"(positive regulation of muscle contraction)|go:"GO:0051020"(GTPase binding)|go:"GO:0061621"(canonical glycolysis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0099738"(cell cortex region)|go:"GO:1903298"(negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway)|go:"GO:2001171"(positive regulation of ATP biosynthetic process)|interpro:IPR000941(Enolase)|interpro:IPR020809|interpro:IPR020810|interpro:IPR020811|interpro:IPR029017|interpro:IPR036849|mint:P06733|rcsb pdb:2PSN|rcsb pdb:3B97|rcsb pdb:5JLZ|rcsb pdb:5LAX|rcsb pdb:5NI9|rcsb pdb:5NIG|rcsb pdb:5OCK|reactome:R-HSA-70171|reactome:R-HSA-70263|reactome:R-HSA-9636667 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RmP7cr55H8ylcgBOEyivwljIE+09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UQN3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-718324|uniprotkb:Q53HC7|uniprotkb:Q9Y4U6|intact:EBI-11161391|uniprotkb:B4DJG8|ensembl:ENSP00000263780 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:chm2b_human(display_long)|uniprotkb:Chromatin-modifying protein 2b(gene name synonym)|uniprotkb:CHMP2.5(gene name synonym)|uniprotkb:Vacuolar protein sorting-associated protein 2-2(gene name synonym)|uniprotkb:CHMP2B(gene name)|psi-mi:CHMP2B(display_short)|uniprotkb:CGI-84(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_054762.2|refseq:NP_001231573.1|ensembl:ENSG00000083937(gene)|ensembl:ENST00000263780(transcript)|go:"GO:0000815"(ESCRT III complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005771"(multivesicular body)|go:"GO:0005829"(cytosol)|go:"GO:0006914"(autophagy)|go:"GO:0006997"(nucleus organization)|go:"GO:0007032"(endosome organization)|go:"GO:0007080"(mitotic metaphase plate congression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015031"(protein transport)|go:"GO:0016236"(macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031902"(late endosome membrane)|go:"GO:0032509"(endosome transport via multivesicular body sorting pathway)|go:"GO:0036258"(multivesicular body assembly)|go:"GO:0039702"(viral budding via host ESCRT complex)|go:"GO:0045296"(cadherin binding)|go:"GO:0045324"(late endosome to vacuole transport)|go:"GO:0050890"(cognition)|go:"GO:0061763"(multivesicular body-lysosome fusion)|go:"GO:0061952"(midbody abscission)|go:"GO:0070050"(neuron cellular homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099159"(regulation of modification of postsynaptic structure)|go:"GO:0099175"(regulation of postsynapse organization)|go:"GO:1901673"(regulation of mitotic spindle assembly)|go:"GO:1902188"(obsolete positive regulation of viral release from host cell)|go:"GO:1904903"(ESCRT III complex disassembly)|interpro:IPR005024(Snf7)|mint:Q9UQN3|rcsb pdb:2JQK|reactome:R-HSA-162588|reactome:R-HSA-1632852|reactome:R-HSA-5620971|reactome:R-HSA-917729|reactome:R-HSA-9610379|reactome:R-HSA-9615710|reactome:R-HSA-9668328|reactome:R-HSA-9679504|reactome:R-HSA-9694676|go:"GO:0010824"(regulation of centrosome duplication)|dip:DIP-50766N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WmtZzxKkbkLsgFov/DJDKKGvIto9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q15758 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-356576|uniprotkb:D0EYG6|uniprotkb:B4DR77|uniprotkb:B7ZB81|uniprotkb:E9PC01|uniprotkb:O95720|uniprotkb:Q96RL9|uniprotkb:Q9BWQ3|uniprotkb:Q9UNP2|uniprotkb:A8K9H5|uniprotkb:B4DWS4|ensembl:ENSP00000444408 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:aaat_human(display_long)|uniprotkb:ASCT2(gene name synonym)|uniprotkb:M7V1(gene name synonym)|uniprotkb:RDR(gene name synonym)|uniprotkb:RDRC(gene name synonym)|uniprotkb:SLC1A5(gene name)|psi-mi:SLC1A5(display_short)|uniprotkb:Sodium-dependent neutral amino acid transporter type 2(gene name synonym)|uniprotkb:RD114/simian type D retrovirus receptor(gene name synonym)|uniprotkb:Baboon M7 virus receptor(gene name synonym)|uniprotkb:Solute carrier family 1 member 5(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001138617.1|refseq:NP_005619.1|refseq:NP_001138616.1|go:"GO:0046872"(metal ion binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070207"(protein homotrimerization)|go:"GO:0140009"(L-aspartate import across plasma membrane)|go:"GO:0150104"(transport across blood-brain barrier)|go:"GO:1903803"(L-glutamine import across plasma membrane)|interpro:IPR001991("Sodium:dicarboxylate symporter")|interpro:IPR018107|interpro:IPR036458|mint:Q15758|rcsb pdb:5LLM|rcsb pdb:5LLU|rcsb pdb:5LM4|rcsb pdb:5MJU|rcsb pdb:6GCT|rcsb pdb:6MP6|rcsb pdb:6MPB|rcsb pdb:6RVX|rcsb pdb:6RVY|reactome:R-HSA-352230|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409|reactome:R-HSA-9013423|go:"GO:0042470"(melanosome)|ensembl:ENSG00000105281(gene)|ensembl:ENST00000542575(transcript)|go:"GO:0001618"(virus receptor activity)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006865"(amino acid transport)|go:"GO:0006868"(glutamine transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0010585"(glutamine secretion)|go:"GO:0015171"(amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015183"(L-aspartate transmembrane transporter activity)|go:"GO:0015186"(L-glutamine transmembrane transporter activity)|go:"GO:0015194"(L-serine transmembrane transporter activity)|go:"GO:0015293"(symporter activity)|go:"GO:0015804"(neutral amino acid transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0038023"(signaling receptor activity) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:nkh427WmAX5SLFm24BvEpyoyAmw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H2G2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1022272|uniprotkb:O00211|uniprotkb:Q6P1Z4|uniprotkb:Q86WU7|uniprotkb:Q86WW1|uniprotkb:Q92603|uniprotkb:Q9NQL0|uniprotkb:Q9NQL1|uniprotkb:D3DRA0|uniprotkb:D3DRA1|ensembl:ENSP00000358770 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:slk_human(display_long)|uniprotkb:STE20-related serine/threonine-protein kinase(gene name synonym)|uniprotkb:Serine/threonine-protein kinase 2(gene name synonym)|uniprotkb:CTCL tumor antigen se20-9(gene name synonym)|uniprotkb:SLK(gene name)|psi-mi:SLK(display_short)|uniprotkb:KIAA0204(gene name synonym)|uniprotkb:STK2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055535.2|refseq:NP_001291672.1|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|interpro:IPR000719(Protein kinase, core)|interpro:IPR001943(UvrB/UvrC protein)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022165|mint:Q9H2G2|rcsb pdb:2J51|rcsb pdb:2JFL|rcsb pdb:2JFM|rcsb pdb:2UV2|rcsb pdb:4USF|rcsb pdb:6HVD|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|ensembl:ENSG00000065613(gene)|ensembl:ENST00000369755(transcript)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0031122"(cytoplasmic microtubule organization)|go:"GO:0031252"(cell leading edge) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:T9Ej6CkWUmqEmPLcptvF2/f1Q+09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UEY8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2838698|uniprotkb:Q9UEY7|uniprotkb:O43243|uniprotkb:Q92773|uniprotkb:Q5VU09|uniprotkb:D3DRA8|intact:EBI-28975834|ensembl:ENSP00000348381 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:addg_human(display_long)|uniprotkb:ADD3(gene name)|psi-mi:ADD3(display_short)|uniprotkb:ADDL(gene name synonym)|uniprotkb:Adducin-like protein 70(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000277900|ensembl:ENSP00000277900|ensembl:ENSP00000348381|ensembl:ENST00000360162|ensembl:ENSP00000353286|refseq:NP_001307520.1|refseq:NP_001307521.1|refseq:NP_001307522.1|refseq:NP_001307523.1|refseq:NP_001112.2|refseq:NP_058432.1|refseq:NP_063968.1|interpro:IPR036409|mint:Q9UEY8|reactome:R-HSA-5223345|reactome:R-HSA-9013405|reactome:R-HSA-9035034|ensembl:ENSG00000148700(gene)|ensembl:ENST00000356080(transcript)|go:"GO:0000794"(condensed nuclear chromosome)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005938"(cell cortex)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0051015"(actin filament binding)|go:"GO:0051016"(barbed-end actin filament capping)|interpro:IPR001303(Class II aldolase/adducin, N-terminal)|interpro:IPR027772 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:10ZAHAI90VaVf/xUxFcNVX5cIts9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5VV41 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1057448|uniprotkb:Q99434|uniprotkb:Q86TF0|ensembl:ENSP00000367629 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:arhgg_human(display_long)|uniprotkb:EPHEXIN4(gene name synonym)|uniprotkb:ARHGEF16(gene name)|psi-mi:ARHGEF16(display_short)|uniprotkb:NBR(gene name synonym)|uniprotkb:Ephexin-4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000130762(gene)|ensembl:ENST00000378378(transcript)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005829"(cytosol)|go:"GO:0030165"(PDZ domain binding)|go:"GO:0030971"(receptor tyrosine kinase binding)|go:"GO:0031267"(small GTPase binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|interpro:IPR000219("Dbl homology (DH) domain")|interpro:IPR001452(Src homology-3)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR035797|interpro:IPR035899|interpro:IPR036028|mint:Q5VV41|rcsb pdb:1X6B|reactome:R-HSA-193648|reactome:R-HSA-416482|reactome:R-HSA-9013148|reactome:R-HSA-9013408|refseq:NP_055263.2|refseq:XP_016856539.1|refseq:XP_016856540.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/HShvoejm8jdWJvRQM2kVNbCC4k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P15311 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1056902|uniprotkb:P23714|uniprotkb:Q4VX75|uniprotkb:Q96CU8|uniprotkb:Q9NSJ4|uniprotkb:E1P5A8|ensembl:ENSP00000338934|ensembl:ENSP00000356042 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ezri_human(display_long)|uniprotkb:EZR(gene name)|psi-mi:EZR(display_short)|uniprotkb:VIL2(gene name synonym)|uniprotkb:p81(gene name synonym)|uniprotkb:Cytovillin(gene name synonym)|uniprotkb:Villin-2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000338934|ensembl:ENSP00000356042|refseq:NP_001104547.1|refseq:NP_003370.2|ensembl:ENSG00000092820(gene)|ensembl:ENST00000337147(transcript)|ensembl:ENST00000367075(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0001772"(immunological synapse)|go:"GO:0001931"(uropod)|go:"GO:0001951"(intestinal D-glucose absorption)|go:"GO:0003376"(sphingosine-1-phosphate receptor signaling pathway)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005903"(brush border)|go:"GO:0005925"(focal adhesion)|go:"GO:0007159"(leukocyte cell-cell adhesion)|go:"GO:0008017"(microtubule binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0019898"(extrinsic component of membrane)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0022614"(membrane to membrane docking)|go:"GO:0030033"(microvillus assembly)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031623"(receptor internalization)|go:"GO:0031982"(vesicle)|go:"GO:0032532"(regulation of microvillus length)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032703"(negative regulation of interleukin-2 production)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034236"(protein kinase A catalytic subunit binding)|go:"GO:0034237"(protein kinase A regulatory subunit binding)|go:"GO:0034629"|go:"GO:0035088"(establishment or maintenance of apical/basal cell polarity)|go:"GO:0036064"(ciliary basal body)|go:"GO:0040018"(positive regulation of multicellular organism growth)|go:"GO:0042802"(identical protein binding)|go:"GO:0042995"(cell projection)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0044297"(cell body)|go:"GO:0044393"(microspike)|go:"GO:0044548"(S100 protein binding)|go:"GO:0044853"(plasma membrane raft)|go:"GO:0045177"(apical part of cell)|go:"GO:0045296"(cadherin binding)|go:"GO:0046847"(filopodium assembly)|go:"GO:0048015"(phosphatidylinositol-mediated signaling)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050860"(negative regulation of T cell receptor signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0051017"(actin filament bundle assembly)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0071320"(cellular response to cAMP)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072697"(protein localization to cell cortex)|go:"GO:0097449"(astrocyte projection)|go:"GO:0097454"(Schwann cell microvillus)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098592"(cytoplasmic side of apical plasma membrane)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902896"(terminal web assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P15311|rcsb pdb:1NI2|rcsb pdb:4RM8|rcsb pdb:4RM9|rcsb pdb:4RMA|reactome:R-HSA-373752|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|dip:DIP-38868N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:tSSki5dutR2qqs2dyN3TqcHyiyM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H425 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11022412|uniprotkb:A8K8R8|uniprotkb:G5EA08|uniprotkb:B3KTW1|intact:EBI-11090756|ensembl:ENSP00000355623 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ca198_human(display_long)|uniprotkb:C1orf198(gene name)|psi-mi:C1orf198(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_016858088.1|refseq:NP_001129966.1|refseq:NP_001129967.1|refseq:NP_116189.1|ensembl:ENSG00000119280(gene)|ensembl:ENST00000366663(transcript)|go:"GO:0005829"(cytosol)|interpro:IPR031600 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:vPJ0HFpmqJM83LuTIWhqgJyySUg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9P0K7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1023749|uniprotkb:Q6V1W9|uniprotkb:Q7Z5I4|uniprotkb:Q7Z733|uniprotkb:Q9P2L2|uniprotkb:Q9Y3T5|uniprotkb:E9PED3|intact:EBI-2555698|ensembl:ENSP00000265109|ensembl:ENSP00000388725|ensembl:ENSP00000422942 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rai14_human(display_long)|uniprotkb:Ankyrin repeat and coiled-coil structure-containing protein(gene name synonym)|uniprotkb:Retinoic acid-induced protein 14(gene name synonym)|uniprotkb:Novel retinal pigment epithelial cell protein(gene name synonym)|uniprotkb:RAI14(gene name)|psi-mi:RAI14(display_short)|uniprotkb:KIAA1334(gene name synonym)|uniprotkb:NORPEG(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001138992.1|refseq:NP_001138993.1|refseq:NP_001138994.1|refseq:NP_001138995.1|refseq:NP_001138997.1|refseq:NP_056392.2|refseq:XP_011512319.1|refseq:XP_011512320.1|refseq:XP_011512321.1|refseq:XP_011512322.1|refseq:XP_011512323.1|refseq:XP_011512324.1|ensembl:ENSG00000039560(gene)|ensembl:ENST00000265109(transcript)|ensembl:ENST00000428746(transcript)|ensembl:ENST00000503673(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0003779"(actin binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005938"(cell cortex)|go:"GO:0007283"(spermatogenesis)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|interpro:IPR002110(Ankyrin)|interpro:IPR020683|interpro:IPR036770|interpro:IPR042420|mint:Q9P0K7|refseq:XP_006714532.1|refseq:XP_016864824.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:m5hQYx6HEi9QEAey1UiNpeAp6tw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P83881 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1054835|uniprotkb:P09896|uniprotkb:P10661|uniprotkb:Q5J9I6|uniprotkb:Q08ES5|ensembl:ENSP00000446503 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl36a_human(display_long)|uniprotkb:60S ribosomal protein L44(gene name synonym)|uniprotkb:Cell migration-inducing gene 6 protein(gene name synonym)|uniprotkb:RPL36A(gene name)|psi-mi:RPL36A(display_short)|uniprotkb:MIG6(orf name)|uniprotkb:RPL44(gene name synonym)|uniprotkb:Cell growth-inhibiting gene 15 protein(gene name synonym)|uniprotkb:GIG15(orf name)|uniprotkb:Large ribosomal subunit protein eL42(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_066357.2|ensembl:ENSG00000241343(gene)|ensembl:ENST00000553110(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:P83881|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:OrRyOEVJZbSdttK93KL/DS5YxJ89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P46108 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-886|uniprotkb:B0LPE8|uniprotkb:Q96HJ0|uniprotkb:A8MWE8|uniprotkb:Q96GA9|uniprotkb:D3DTH6|intact:EBI-28974221|ensembl:ENSP00000300574|intact:EBI-16429791 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:crk_human(display_long)|uniprotkb:Proto-oncogene c-Crk(gene name synonym)|uniprotkb:CRK(gene name)|psi-mi:CRK(display_short)|uniprotkb:p38(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000300574|ensembl:ENST00000398970|ensembl:ENSP00000381942|refseq:NP_005197.3|refseq:NP_058431.2|ensembl:ENSG00000167193(gene)|ensembl:ENST00000300574(transcript)|go:"GO:0001764"(neuron migration)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001878"(response to yeast)|go:"GO:0005159"(insulin-like growth factor receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008360"(regulation of cell shape)|dip:DIP-199N|go:"GO:0009966"(regulation of signal transduction)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016358"(dendrite development)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0019900"(kinase binding)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030159"(signaling receptor complex adaptor activity)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035020"(regulation of Rac protein signal transduction)|go:"GO:0035591"(signaling adaptor activity)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035728"(response to hepatocyte growth factor)|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042169"(SH2 domain binding)|go:"GO:0042542"(response to hydrogen peroxide)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043393"(regulation of protein binding)|go:"GO:0043621"(protein self-association)|go:"GO:0045121"(membrane raft)|go:"GO:0045309"(protein phosphorylated amino acid binding)|go:"GO:0045953"(negative regulation of natural killer cell mediated cytotoxicity)|go:"GO:0046875"(ephrin receptor binding)|go:"GO:0048013"(ephrin receptor signaling pathway)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0061045"(negative regulation of wound healing)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0071732"(cellular response to nitric oxide)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1902531"(regulation of intracellular signal transduction)|go:"GO:1990090"(cellular response to nerve growth factor stimulus)|go:"GO:1990314"(cellular response to insulin-like growth factor stimulus)|go:"GO:1990782"(protein tyrosine kinase binding)|go:"GO:1990859"(cellular response to endothelin)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46108|rcsb pdb:1JU5|rcsb pdb:2DVJ|rcsb pdb:2EYV|rcsb pdb:2EYW|rcsb pdb:2EYX|rcsb pdb:2EYY|rcsb pdb:2EYZ|rcsb pdb:2MS4|rcsb pdb:5UL6|rcsb pdb:6ATV|reactome:R-HSA-170984|reactome:R-HSA-186763|reactome:R-HSA-2029482|reactome:R-HSA-372708|reactome:R-HSA-4420097|reactome:R-HSA-8849471|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-912631|reactome:R-HSA-9664422 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lIXCzFxFvmvsfPaLQIKV9QS75cw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9HAU0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-945934|uniprotkb:Q86ST7|uniprotkb:A0JP03|uniprotkb:Q8N3K6|uniprotkb:Q96DY9|uniprotkb:Q9BVR4|uniprotkb:Q9C0H7|uniprotkb:Q9H924|uniprotkb:Q9NVK8|uniprotkb:B4DGS1|uniprotkb:F5H0I0|uniprotkb:E9PHQ3|uniprotkb:Q6NSF8|ensembl:ENSP00000299275 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkha5_human(display_long)|uniprotkb:PLEKHA5(gene name)|psi-mi:PLEKHA5(display_short)|uniprotkb:KIAA1686(gene name synonym)|uniprotkb:PEPP2(gene name synonym)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000299275|ensembl:ENST00000424268|ensembl:ENSP00000400411|ensembl:ENST00000429027|ensembl:ENSP00000404296|ensembl:ENST00000538714|ensembl:ENSP00000439673|ensembl:ENST00000540972|ensembl:ENSP00000439396|refseq:NP_001137293.2|refseq:NP_061885.2|refseq:NP_001177789.2|refseq:NP_001243399.1|refseq:NP_001243716.1|refseq:XP_005253457.1|refseq:XP_016874992.1|refseq:XP_011519019.1|ensembl:ENSG00000052126(gene)|ensembl:ENST00000299275(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010314"(phosphatidylinositol-5-phosphate binding)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0032266"(phosphatidylinositol-3-phosphate binding)|go:"GO:0061458"(reproductive system development)|go:"GO:0070273"(phosphatidylinositol-4-phosphate binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0098978"(glutamatergic synapse)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036020|interpro:IPR040392|mint:Q9HAU0|rcsb pdb:2DKP|reactome:R-HSA-1660499 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:22W2zdIwTLw4nNRh0dHasYDCLK49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UPQ0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2687222|uniprotkb:Q8N3S9|uniprotkb:Q5H9S8|uniprotkb:Q6PJ44|uniprotkb:Q5CZB6|uniprotkb:Q5CZB1|uniprotkb:Q503B5|uniprotkb:Q8N6M2|uniprotkb:Q68E07|uniprotkb:Q7Z3G5|uniprotkb:A8MXC3|uniprotkb:E9PHM7|intact:EBI-10977823|ensembl:ENSP00000316891 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:limc1_human(display_long)|uniprotkb:KIAA1102(gene name synonym)|uniprotkb:LIMCH1(gene name)|psi-mi:LIMCH1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001106188.1|refseq:NP_001106189.1|refseq:NP_001106190.1|refseq:NP_001106191.1|refseq:NP_055803.2|refseq:NP_001276051.1|refseq:NP_001276053.1|ensembl:ENSG00000064042(gene)|ensembl:ENST00000313860(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032034"(myosin II head/neck binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051496"(positive regulation of stress fiber assembly)|go:"GO:0051893"(regulation of focal adhesion assembly)|go:"GO:0060327"(cytoplasmic actin-based contraction involved in cell motility)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR001997(Calponin)|interpro:IPR003096(SM22/calponin)|interpro:IPR029980|interpro:IPR031865|interpro:IPR036872|refseq:NP_001317601.1|refseq:NP_001317603.1|refseq:NP_001317713.1|refseq:NP_001317715.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:neDT1Rx97o6shpmtkOqJy31ueTA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P14618 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353408|uniprotkb:A6NFK3|uniprotkb:P14786|uniprotkb:Q53GK4|uniprotkb:Q96E76|uniprotkb:Q9BWB5|uniprotkb:Q9UPF2|uniprotkb:B2R5N8|uniprotkb:B3KRY0|uniprotkb:B4DFX8|uniprotkb:Q9UCV6|intact:EBI-2555890|uniprotkb:B4DUU6|ensembl:ENSP00000334983 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:kpym_human(display_long)|uniprotkb:PKM(gene name)|psi-mi:PKM(display_short)|uniprotkb:Cytosolic thyroid hormone-binding protein(gene name synonym)|uniprotkb:OIP3(gene name synonym)|uniprotkb:Opa-interacting protein 3(gene name synonym)|uniprotkb:PK2(gene name synonym)|uniprotkb:PK3(gene name synonym)|uniprotkb:PKM2(gene name synonym)|uniprotkb:Pyruvate kinase 2/3(gene name synonym)|uniprotkb:Pyruvate kinase muscle isozyme(gene name synonym)|uniprotkb:Thyroid hormone-binding protein 1(gene name synonym)|uniprotkb:Tumor M2-PK(gene name synonym)|uniprotkb:p58(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001193725.1|refseq:NP_001193727.1|refseq:NP_001193728.1|refseq:NP_002645.3|refseq:NP_872270.1|refseq:NP_872271.1|refseq:NP_001193726.1|refseq:NP_001303247.1|refseq:XP_005254502.1|dip:DIP-31273N|ensembl:ENSG00000067225(gene)|ensembl:ENST00000335181(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0004743"(pyruvate kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005929"(cilium)|go:"GO:0006096"(glycolytic process)|go:"GO:0012501"(programmed cell death)|go:"GO:0016301"(kinase activity)|go:"GO:0023026"(MHC class II protein complex binding)|go:"GO:0030955"(potassium ion binding)|go:"GO:0031982"(vesicle)|go:"GO:0032869"(cellular response to insulin stimulus)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0045296"(cadherin binding)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|go:"GO:2000767"(positive regulation of cytoplasmic translation)|interpro:IPR001697(Pyruvate kinase)|interpro:IPR011037(Pyruvate kinase, beta-barrel-like)|interpro:IPR015793(Pyruvate kinase, barrel)|interpro:IPR015795(Pyruvate kinase, C-terminal-like)|interpro:IPR015806(Pyruvate kinase, beta-barrel)|interpro:IPR015813(Pyruvate/Phosphoenolpyruvate kinase, catalytic core)|interpro:IPR018209|interpro:IPR036918|interpro:IPR040442|mint:P14618|rcsb pdb:1T5A|rcsb pdb:1ZJH|rcsb pdb:3BJF|rcsb pdb:3BJT|rcsb pdb:3G2G|rcsb pdb:3GQY|rcsb pdb:3GR4|rcsb pdb:3H6O|rcsb pdb:3ME3|rcsb pdb:3SRD|rcsb pdb:3SRF|rcsb pdb:3U2Z|rcsb pdb:4B2D|rcsb pdb:4FXF|rcsb pdb:4FXJ|rcsb pdb:4G1N|rcsb pdb:4JPG|rcsb pdb:4QG6|rcsb pdb:4QG8|rcsb pdb:4QG9|rcsb pdb:4QGC|rcsb pdb:4RPP|rcsb pdb:4WJ8|rcsb pdb:4YJ5|rcsb pdb:5X0I|rcsb pdb:5X1V|rcsb pdb:5X1W|rcsb pdb:6B6U|rcsb pdb:6GG3|rcsb pdb:6GG4|rcsb pdb:6GG5|rcsb pdb:6GG6|rcsb pdb:6JFB|rcsb pdb:6NU1|rcsb pdb:6NU5|rcsb pdb:6NUB|rcsb pdb:6TTF|rcsb pdb:6TTH|rcsb pdb:6TTI|rcsb pdb:6TTQ|rcsb pdb:6V74|rcsb pdb:3SRH|rcsb pdb:6V75|rcsb pdb:6V76|rcsb pdb:6WP3|rcsb pdb:6WP4|rcsb pdb:6WP5|rcsb pdb:6WP6|reactome:R-HSA-6798695|reactome:R-HSA-70171|refseq:XP_016877802.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:dDaoXCaqd0x6qFSElvngHusttuk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y4K1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-5453777|uniprotkb:B4DU04|uniprotkb:O00296|uniprotkb:Q5VWJ2 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:crbg1_human(display_long)|uniprotkb:CRYBG1(gene name)|psi-mi:CRYBG1(display_short)|uniprotkb:AIM1(gene name synonym)|uniprotkb:Absent in melanoma 1 protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001615.2|interpro:IPR001064(Beta and gamma crystallin)|interpro:IPR011024(Gamma-crystallin related)|interpro:IPR000772(Ricin B lectin)|rcsb pdb:2DAD|rcsb pdb:3CW3|interpro:IPR035992|rcsb pdb:6VRO|go:"GO:0030246"(carbohydrate binding) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:mdQxrU/fgkY/DzoaZsyeED+jPFk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q6UWP8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-11024569|uniprotkb:E9PBV3|uniprotkb:A8K5J0|ensembl:ENSP00000430242 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sbsn_human(display_long)|uniprotkb:SBSN(gene name)|psi-mi:SBSN(display_short)|uniprotkb:UNQ698/PRO1343(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001159506.1|refseq:NP_001159507.1|refseq:NP_940940.1|ensembl:ENSG00000189001(gene)|ensembl:ENST00000452271(transcript)|go:"GO:0070062"(extracellular exosome) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:odagYPEdS9Vav1RDWyUv1l+lQA49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q92817 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3447371|uniprotkb:A0AUV5|ensembl:ENSP00000301607 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:evpl_human(display_long)|uniprotkb:EVPL(gene name)|psi-mi:EVPL(display_short)|uniprotkb:210 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:210 kDa paraneoplastic pemphigus antigen(gene name synonym)|uniprotkb:p210(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001307676.1|refseq:NP_001979.2|ensembl:ENSG00000167880(gene)|ensembl:ENST00000301607(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008544"(epidermis development)|go:"GO:0016020"(membrane)|go:"GO:0019215"(intermediate filament binding)|go:"GO:0030057"(desmosome)|go:"GO:0030216"(keratinocyte differentiation)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045111"(intermediate filament cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR030460|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|mint:Q92817|rcsb pdb:4QMD|reactome:R-HSA-6809371|go:"GO:0018149"(peptide cross-linking) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:KPm64OC6taugW179BA0vT7JEt9U9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O75367 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2868511|uniprotkb:Q7Z5E3|uniprotkb:Q9UP96|uniprotkb:Q9H8P3|uniprotkb:Q503A8|uniprotkb:O75377|uniprotkb:Q96D41|ensembl:ENSP00000423563|ensembl:ENSP00000424971 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:h2ay_human(display_long)|uniprotkb:MACROH2A1(gene name)|psi-mi:MACROH2A1(display_short)|uniprotkb:H2AFY(gene name synonym)|uniprotkb:Histone H2A.y(gene name synonym)|uniprotkb:Medulloblastoma antigen MU-MB-50.205(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011542031.1|refseq:XP_011542032.1|refseq:NP_001035248.1|refseq:NP_004884.1|refseq:NP_613075.1|refseq:NP_613258.2|dip:DIP-44283N|ensembl:ENSG00000113648(gene)|ensembl:ENST00000510038(transcript)|ensembl:ENST00000511689(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000182"(rDNA binding)|go:"GO:0000228"(nuclear chromosome)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000786"(nucleosome)|go:"GO:0000793"(condensed chromosome)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0000977"(RNA polymerase II transcription regulatory region sequence-specific DNA binding)|go:"GO:0001739"(sex chromatin)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006342"|go:"GO:0007549"(dosage compensation)|go:"GO:0010385"(double-stranded methylated DNA binding)|go:"GO:0019216"(regulation of lipid metabolic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030291"(protein serine/threonine kinase inhibitor activity)|go:"GO:0031490"(chromatin DNA binding)|go:"GO:0031492"(nucleosomal DNA binding)|go:"GO:0033128"(negative regulation of histone phosphorylation)|go:"GO:0034184"(positive regulation of maintenance of mitotic sister chromatid cohesion)|go:"GO:0040029"(regulation of gene expression, epigenetic)|go:"GO:0045618"(positive regulation of keratinocyte differentiation)|go:"GO:0045814"(negative regulation of gene expression, epigenetic)|go:"GO:0000979"(RNA polymerase II core promoter sequence-specific DNA binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051572"(negative regulation of histone H3-K4 methylation)|go:"GO:0061086"(negative regulation of histone H3-K27 methylation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071169"(establishment of protein localization to chromatin)|go:"GO:0071901"(negative regulation of protein serine/threonine kinase activity)|go:"GO:1901837"(negative regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1902750"(negative regulation of cell cycle G2/M phase transition)|go:"GO:1902882"(regulation of response to oxidative stress)|go:"GO:1902883"(negative regulation of response to oxidative stress)|go:"GO:1902884"(positive regulation of response to oxidative stress)|go:"GO:1903226"(positive regulation of endodermal cell differentiation)|go:"GO:1904815"(negative regulation of protein localization to chromosome, telomeric region)|go:"GO:1990841"(promoter-specific chromatin binding)|go:"GO:0045815"(epigenetic maintenance of chromatin in transcription-competent conformation)|interpro:IPR002589(Appr-1-p processing)|interpro:IPR007125(Histone core)|interpro:IPR009072(Histone-fold)|interpro:IPR021171|interpro:IPR032454|interpro:IPR035796|interpro:IPR043472|mint:O75367|rcsb pdb:1U35|rcsb pdb:1ZR3|rcsb pdb:1ZR5|rcsb pdb:2F8N|rcsb pdb:2FXK|rcsb pdb:3HQH|rcsb pdb:3HSV|rcsb pdb:3IID|rcsb pdb:3IIF|rcsb pdb:3IVB|rcsb pdb:5IIT|rcsb pdb:5LNC|interpro:IPR002119(Histone H2A) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0FCoM0/4mTtnc7cPDUleKuZ3HgM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14126 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2556545|uniprotkb:Q4KKU6|ensembl:ENSP00000261590 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dsg2_human(display_long)|uniprotkb:CDHF5(gene name synonym)|uniprotkb:HDGC(gene name synonym)|uniprotkb:Cadherin family member 5(gene name synonym)|uniprotkb:DSG2(gene name)|psi-mi:DSG2(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001934.2|reactome:R-HSA-9013423|ensembl:ENSG00000046604(gene)|ensembl:ENST00000261590(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0002934"(desmosome organization)|go:"GO:0003165"(Purkinje myocyte development)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0009986"(cell surface)|go:"GO:0014704"(intercalated disc)|go:"GO:0016021"(integral component of membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|interpro:IPR002126(Cadherin)|interpro:IPR009122(Desmosomal cadherin)|interpro:IPR009123(Desmoglein)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|rcsb pdb:2YQG|rcsb pdb:5ERD|rcsb pdb:5J5J|rcsb pdb:6QNT|rcsb pdb:6QNU|rcsb pdb:6SIT|rcsb pdb:7A7D|rcsb pdb:7AGF|rcsb pdb:7AGG|reactome:R-HSA-351906|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-9013404|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|reactome:R-HSA-9013408|dip:DIP-46250N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:LCSf84WRgh5lTrze5IEzFaBeuEc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15498 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4402903|uniprotkb:Q53F01|uniprotkb:Q6FGU9|uniprotkb:Q6IB15|uniprotkb:B4DR94|ensembl:ENSP00000223369|ensembl:ENSP00000504623 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ykt6_human(display_long)|uniprotkb:YKT6(gene name)|psi-mi:YKT6(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006546.1|refseq:XP_016867171.1|go:"GO:0031201"(SNARE complex)|go:"GO:0033116"(endoplasmic reticulum-Golgi intermediate compartment membrane)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045296"(cadherin binding)|go:"GO:0097440"(apical dendrite)|go:"GO:0097441"(basal dendrite)|interpro:IPR001388(Synaptobrevin)|interpro:IPR010908(Longin)|interpro:IPR011012(Longin-like)|interpro:IPR042855|rcsb pdb:6J74|rcsb pdb:6J7F|rcsb pdb:6J7X|reactome:R-HSA-204005|reactome:R-HSA-6807878|reactome:R-HSA-6811438|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013408|reactome:R-HSA-9013423|go:"GO:0030659"(cytoplasmic vesicle membrane)|ensembl:ENSG00000106636(gene)|ensembl:ENST00000223369(transcript)|ensembl:ENST00000679020(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005768"(endosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0006888"(endoplasmic reticulum to Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006904"(vesicle docking involved in exocytosis)|go:"GO:0015031"(protein transport)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030133"(transport vesicle) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:pkTOoQ9XXEVYHKNvqOMCU6x4nZg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14847 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-742828|uniprotkb:Q96ED2|uniprotkb:Q96IG0|ensembl:ENSP00000325240|ensembl:ENSP00000392853|uniprotkb:B4DGQ0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lasp1_human(display_long)|uniprotkb:Metastatic lymph node gene 50 protein(gene name synonym)|uniprotkb:LASP1(gene name)|psi-mi:LASP1(display_short)|uniprotkb:MLN50(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_006139.1|refseq:NP_001258537.1|ensembl:ENSG00000002834(gene)|ensembl:ENST00000318008(transcript)|ensembl:ENST00000435347(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005925"(focal adhesion)|go:"GO:0006811"(ion transport)|go:"GO:0015075"(ion transmembrane transporter activity)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0045296"(cadherin binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0051015"(actin filament binding)|interpro:IPR000900(Nebulin 35 residue motif)|interpro:IPR001452(Src homology-3)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR035630|interpro:IPR036028|mint:Q14847|rcsb pdb:3I35 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Oa+FdJXeQhahYTqVrHYk6yBrUWI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y6R0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-945925|uniprotkb:Q7Z4J9|intact:EBI-28967671|ensembl:ENSP00000252891 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:numbl_human(display_long)|uniprotkb:NUMBL(gene name)|psi-mi:NUMBL(display_short)|uniprotkb:Numb-related protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000252891|refseq:NP_004747.1|refseq:NP_001276908.1|refseq:NP_001276909.1|ensembl:ENSG00000105245(gene)|ensembl:ENST00000252891(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0007399"(nervous system development)|go:"GO:0007409"(axonogenesis)|go:"GO:0019221"(cytokine-mediated signaling pathway)|go:"GO:0019538"(protein metabolic process)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0034332"(adherens junction organization)|go:"GO:0050769"(positive regulation of neurogenesis)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|rcsb pdb:3F0W - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:pqFj8N7B2oKcFSMWPs/wX1zdO2Y9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14677 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1171113|uniprotkb:Q8NAF1|uniprotkb:Q96E05|uniprotkb:D3DQJ6|uniprotkb:B7Z6F8|intact:EBI-28971708|ensembl:ENSP00000388340 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:epn4_human(display_long)|uniprotkb:CLINT1(gene name)|psi-mi:CLINT1(display_short)|uniprotkb:ENTH(gene name synonym)|uniprotkb:EPN4(gene name synonym)|uniprotkb:EPNR(gene name synonym)|uniprotkb:KIAA0171(gene name synonym)|uniprotkb:Epsin-4(gene name synonym)|uniprotkb:Epsin-related protein(gene name synonym)|uniprotkb:Enthoprotin(gene name synonym)|uniprotkb:Clathrin-interacting protein localized in the trans-Golgi region(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000388340|ensembl:ENST00000523094|ensembl:ENSP00000429345|ensembl:ENST00000523908|ensembl:ENSP00000429824|ensembl:ENST00000530742|ensembl:ENSP00000433419|refseq:NP_001182484.1|refseq:NP_001182485.1|refseq:NP_055481.1|ensembl:ENSG00000113282(gene)|ensembl:ENST00000411809(transcript)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006897"(endocytosis)|go:"GO:0016020"(membrane)|go:"GO:0030125"(clathrin vesicle coat)|go:"GO:0030276"(clathrin binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0048268"(clathrin coat assembly)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR008942(ENTH/VHS)|interpro:IPR013809(Epsin-like, N-terminal)|interpro:IPR030544|mint:Q14677|rcsb pdb:1XGW|rcsb pdb:2QY7|rcsb pdb:2V8S|reactome:R-HSA-432722|dip:DIP-45604N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:cflzNAWnEQR6zTr4d+hwfy1doC49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T5U3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1642518|uniprotkb:Q8NI19|uniprotkb:Q0VF98|uniprotkb:Q7Z3P7|uniprotkb:Q8N3A2|uniprotkb:Q8TBV5|uniprotkb:Q9P2C3|ensembl:ENSP00000379709 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rhg21_human(display_long)|uniprotkb:ARHGAP21(gene name)|psi-mi:ARHGAP21(display_short)|uniprotkb:ARHGAP10(gene name synonym)|uniprotkb:KIAA1424(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 21(gene name synonym)|uniprotkb:Rho GTPase-activating protein 10(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_065875.3|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-9696264|reactome:R-HSA-9013148|ensembl:ENSG00000107863(gene)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007030"(Golgi organization)|go:"GO:0007165"(signal transduction)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0030054"(cell junction)|go:"GO:0030659"(cytoplasmic vesicle membrane)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:0051645"(Golgi localization)|ensembl:ENST00000396432(transcript)|go:"GO:0051683"(establishment of Golgi localization)|go:"GO:0051684"(maintenance of Golgi location)|go:"GO:0000139"(Golgi membrane)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0072384"(organelle transport along microtubule)|interpro:IPR000198(RhoGAP)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR036034|interpro:IPR041489|mint:Q5T5U3|rcsb pdb:2DHJ|rcsb pdb:2J59|rcsb pdb:2YUY|reactome:R-HSA-8980692|reactome:R-HSA-9013026|go:"GO:0005794"(Golgi apparatus)|reactome:R-HSA-9013106|refseq:XP_005252599.1|refseq:XP_016871948.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:oXBGm9w5FjXr9jPDxzrx856rtck9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9C0B5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2799626|uniprotkb:Q8TAK8|uniprotkb:Q9H923|uniprotkb:Q9UFI7|uniprotkb:Q6ZMF0|uniprotkb:Q2TGF0|ensembl:ENSP00000287169 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zdhc5_human(display_long)|uniprotkb:KIAA1748(gene name synonym)|uniprotkb:ZNF375(gene name synonym)|uniprotkb:Zinc finger DHHC domain-containing protein 5(gene name synonym)|uniprotkb:Zinc finger protein 375(gene name synonym)|uniprotkb:ZDHHC5(gene name)|psi-mi:ZDHHC5(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011543201.1|refseq:XP_011543202.1|refseq:XP_011543203.1|refseq:NP_056272.2|ensembl:ENSG00000156599(gene)|ensembl:ENST00000287169(transcript)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016409"(palmitoyltransferase activity)|go:"GO:0018345"(protein palmitoylation)|go:"GO:0019706"(protein-cysteine S-palmitoyltransferase activity)|go:"GO:0030425"(dendrite)|go:"GO:0045335"(phagocytic vesicle)|go:"GO:0062208"(positive regulation of pattern recognition receptor signaling pathway)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1905171"(positive regulation of protein localization to phagocytic vesicle)|interpro:IPR001594(Zinc finger, DHHC-type) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:4EKCQeKXifPU/7fv6uPuHE7b1rU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9H4G0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-465536|uniprotkb:O15046|intact:EBI-28979321|ensembl:ENSP00000337168|uniprotkb:Q4VXM6|uniprotkb:Q4VXM7|uniprotkb:Q4VXM8|uniprotkb:Q4VXN4|uniprotkb:Q6ZT61|uniprotkb:Q8IUU7|uniprotkb:Q96CV5|uniprotkb:Q96L65 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:e41l1_human(display_long)|uniprotkb:EPB41L1(gene name)|psi-mi:EPB41L1(display_short)|uniprotkb:KIAA0338(gene name synonym)|uniprotkb:Neuronal protein 4.1(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1-like 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N reactome:R-HSA-6794361|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000338074(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|reactome:R-HSA-399719|ensembl:ENSG00000088367(gene)|refseq:NP_036288.2|refseq:NP_818932.1|ensembl:ENSP00000487049|ensembl:ENST00000202028|ensembl:ENSP00000202028|ensembl:ENSP00000337168|ensembl:ENST00000373950|ensembl:ENSP00000363061|ensembl:ENST00000441639|ensembl:ENSP00000399214|ensembl:ENST00000628415|refseq:NP_001245258.1|refseq:NP_001245259.1|refseq:NP_001245260.1|refseq:XP_016883205.1|refseq:XP_016883206.1|refseq:XP_016883208.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xjD0lRYDp3hSQcr+y1zYyNN+HBc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UDY2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1042602|uniprotkb:Q15883|uniprotkb:Q5VXL0|uniprotkb:Q8N756|uniprotkb:Q8NI14|uniprotkb:Q99839|uniprotkb:Q9UDY0|uniprotkb:Q9UDY1|uniprotkb:A2A3H9|uniprotkb:Q5VXL1|intact:EBI-10989219|ensembl:ENSP00000366453|uniprotkb:B7Z2R8|uniprotkb:B7Z7T6|uniprotkb:F5H301|uniprotkb:F5H886 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zo2_human(display_long)|uniprotkb:TJP2(gene name)|psi-mi:TJP2(display_short)|uniprotkb:X104(gene name synonym)|uniprotkb:Zonula occludens protein 2(gene name synonym)|uniprotkb:Zona occludens protein 2(gene name synonym)|uniprotkb:Tight junction protein 2(gene name synonym)|uniprotkb:ZO2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001163886.1|refseq:NP_001163887.1|refseq:NP_004808.2|refseq:XP_011517508.1|refseq:XP_011517509.1|refseq:XP_011517510.1|refseq:XP_011517511.1|ensembl:ENSG00000119139(gene)|ensembl:ENST00000377245(transcript)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0034109"(homotypic cell-cell adhesion)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050892"(intestinal absorption)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0090559"(regulation of membrane permeability)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:1990782"(protein tyrosine kinase binding)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005419(Zona occludens protein ZO-2)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR035598|interpro:IPR036028|interpro:IPR036034|mint:Q9UDY2|rcsb pdb:2OSG|rcsb pdb:3E17|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:iN/EF8QWKtekoj5eON764eKAdpg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q06830 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353193|ensembl:ENSP00000262746|ensembl:ENSP00000361152|ensembl:ENSP00000389047|ensembl:ENSP00000407034|ensembl:ENSP00000503140|uniprotkb:P35703|uniprotkb:Q2V576|uniprotkb:Q5T154|uniprotkb:Q5T155|uniprotkb:B5BU26|uniprotkb:D3DPZ8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:prdx1_human(display_long)|uniprotkb:PRDX1(gene name)|psi-mi:PRDX1(display_short)|uniprotkb:PAGA(gene name synonym)|uniprotkb:PAGB(gene name synonym)|uniprotkb:TDPX2(gene name synonym)|uniprotkb:Thioredoxin peroxidase 2(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxide reductase 2(gene name synonym)|uniprotkb:Proliferation-associated gene protein(gene name synonym)|uniprotkb:Natural killer cell-enhancing factor A(gene name synonym)|uniprotkb:Thioredoxin-dependent peroxiredoxin 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000117450(gene)|ensembl:ENST00000262746(transcript)|ensembl:ENST00000319248(transcript)|ensembl:ENST00000424390(transcript)|ensembl:ENST00000447184(transcript)|ensembl:ENST00000676549(transcript)|go:"GO:0001895"(retina homeostasis)|go:"GO:0003723"(RNA binding)|go:"GO:0001501"(skeletal system development)|go:"GO:0004601"(peroxidase activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0008283"(cell population proliferation)|go:"GO:0008379"(thioredoxin peroxidase activity)|go:"GO:0019430"(removal of superoxide radicals)|go:"GO:0030101"(natural killer cell activation)|go:"GO:0032872"(regulation of stress-activated MAPK cascade)|go:"GO:0034101"(erythrocyte homeostasis)|go:"GO:0042267"(natural killer cell mediated cytotoxicity)|go:"GO:0042470"(melanosome)|go:"GO:0042744"(hydrogen peroxide catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045321"(leukocyte activation)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0070062"(extracellular exosome)|go:"GO:1901222"(regulation of NIK/NF-kappaB signaling)|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|mint:Q06830|rcsb pdb:2RII|rcsb pdb:3HY2|rcsb pdb:4XCS|reactome:R-HSA-3299685|reactome:R-HSA-5628897|reactome:R-HSA-8862803|refseq:NP_001189360.1|refseq:NP_002565.1|refseq:NP_859047.1|refseq:NP_859048.1|dip:DIP-33152N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZM5ZXF900izH81QVqgd2+opwMrs9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96HC4 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-751267|uniprotkb:Q8WVK0|uniprotkb:O60705|uniprotkb:A8K6F9|uniprotkb:Q5UW38|uniprotkb:D6RB78|uniprotkb:E9PBF5|uniprotkb:Q56VN4|ensembl:ENSP00000321746 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pdli5_human(display_long)|uniprotkb:Enigma homolog(gene name synonym)|uniprotkb:Enigma-like PDZ and LIM domains protein(gene name synonym)|uniprotkb:PDLIM5(gene name)|psi-mi:PDLIM5(display_short)|uniprotkb:L9(orf name)|uniprotkb:ENH(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001011515.1|refseq:NP_001011516.1|refseq:NP_006448.4|refseq:NP_001243358.1|mint:Q96HC4|rcsb pdb:2DAR|rcsb pdb:2UZC|reactome:R-HSA-6794361|interpro:IPR036034|ensembl:ENSG00000163110(gene)|ensembl:ENST00000317968(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003779"(actin binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005912"(adherens junction)|go:"GO:0007507"(heart development)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0031941"(filamentous actin)|go:"GO:0042805"(actinin binding)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0051963"(regulation of synapse assembly)|go:"GO:0061001"(regulation of dendritic spine morphogenesis)|go:"GO:0061049"(cell growth involved in cardiac muscle cell development)|go:"GO:0061061"(muscle structure development)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:0098793"(presynapse)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|interpro:IPR031847|go:"GO:0005829"(cytosol)|dip:DIP-34898N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ngp310yfoOv8KaxchoUc39mj5HE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35241 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2514878|ensembl:ENSP00000496503|uniprotkb:Q86Y61|uniprotkb:A7YIK0|uniprotkb:A7YIK3|uniprotkb:A7YIJ8|uniprotkb:B7Z9U6|uniprotkb:F5H1A7 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:radi_human(display_long)|uniprotkb:RDX(gene name)|psi-mi:RDX(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000137710(gene)|ensembl:ENST00000645495(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003779"(actin binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005886"(plasma membrane)|go:"GO:0005902"(microvillus)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0008361"(regulation of cell size)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010737"(protein kinase A signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030027"(lamellipodium)|go:"GO:0030175"(filopodium)|go:"GO:0030315"(T-tubule)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030496"(midbody)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032154"(cleavage furrow)|go:"GO:0032231"(regulation of actin filament bundle assembly)|go:"GO:0032487"(regulation of Rap protein signal transduction)|go:"GO:0034111"(negative regulation of homotypic cell-cell adhesion)|go:"GO:0034260"(negative regulation of GTPase activity)|go:"GO:0036120"(cellular response to platelet-derived growth factor stimulus)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0045176"(apical protein localization)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0045792"(negative regulation of cell size)|go:"GO:0051016"(barbed-end actin filament capping)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051286"(cell tip)|go:"GO:0061028"(establishment of endothelial barrier)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071944"(cell periphery)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097067"(cellular response to thyroid hormone stimulus)|go:"GO:1900027"(regulation of ruffle assembly)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1902115"(regulation of organelle assembly)|go:"GO:1902966"(positive regulation of protein localization to early endosome)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:2000643"(positive regulation of early endosome to late endosome transport)|go:"GO:1903392"(negative regulation of adherens junction organization)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR008954(Moesin)|interpro:IPR011174(Ezrin/radixin/moesin)|interpro:IPR011259(Ezrin/radixin/moesin, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR029071|interpro:IPR035963|interpro:IPR041789|mint:P35241|reactome:R-HSA-437239|reactome:R-HSA-9662360|reactome:R-HSA-9662361|refseq:NP_002897.1|refseq:NP_001247423.1|refseq:NP_001247424.1|refseq:NP_001247425.1|refseq:NP_001247421.1|refseq:NP_001247422.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:75lzbINdL0deHtiWY7IwioSh5749606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P50914 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-356746|uniprotkb:Q45RF0|uniprotkb:Q53G20|uniprotkb:Q8TBD5|uniprotkb:Q8WUT0|uniprotkb:Q92579|uniprotkb:Q96GR0|uniprotkb:Q9BSB8|uniprotkb:Q9BW65|uniprotkb:Q9BYF6|ensembl:ENSP00000345156|ensembl:ENSP00000379506 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl14_human(display_long)|uniprotkb:RPL14(gene name)|psi-mi:RPL14(display_short)|uniprotkb:CAG-ISL 7(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL14(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001030168.1|refseq:NP_003964.3|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002784(Ribosomal protein L14)|interpro:IPR008991(Translation protein SH3-like)|ensembl:ENSG00000188846(gene)|ensembl:ENST00000338970(transcript)|ensembl:ENST00000396203(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041985|mint:P50914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|interpro:IPR039660|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y2L - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:AjaguD5hgHtcBbJq5QfuG6XdTcE9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y5K6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-298152|uniprotkb:A6NL34|uniprotkb:Q5VYA3|uniprotkb:Q9UG97|ensembl:ENSP00000352264 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cd2ap_human(display_long)|uniprotkb:CD2AP(gene name)|psi-mi:CD2AP(display_short)|uniprotkb:Cas ligand with multiple SH3 domains(gene name synonym)|uniprotkb:Adapter protein CMS(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000198087(gene)|ensembl:ENST00000359314(transcript)|go:"GO:0001650"(fibrillar center)|go:"GO:0001726"(ruffle)|go:"GO:0005172"(vascular endothelial growth factor receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0007015"(actin filament organization)|go:"GO:0007049"(cell cycle)|go:"GO:0007165"(signal transduction)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016050"(vesicle organization)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030139"(endocytic vesicle)|go:"GO:0030424"(axon)|go:"GO:0030425"(dendrite)|go:"GO:0031941"(filamentous actin)|go:"GO:0032911"(negative regulation of transforming growth factor beta1 production)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042802"(identical protein binding)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048259"(regulation of receptor-mediated endocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0051058"(negative regulation of small GTPase mediated signal transduction)|go:"GO:0051301"(cell division)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:2000249"(regulation of actin cytoskeleton reorganization)|interpro:IPR001452(Src homology-3)|interpro:IPR028445|interpro:IPR035775|interpro:IPR035776|interpro:IPR035777|interpro:IPR036028|mint:Q9Y5K6|rcsb pdb:2FEI|rcsb pdb:2J6F|rcsb pdb:2J6K|rcsb pdb:2J6O|rcsb pdb:2J7I|rcsb pdb:3AA6|rcsb pdb:3LK4|rcsb pdb:3U23|rcsb pdb:4WCI|rcsb pdb:4X1V|rcsb pdb:7DS6|rcsb pdb:7DS8|reactome:R-HSA-373753|refseq:NP_036252.1|dip:DIP-31807N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:T0OYMq1jOCwVMJOxnrPg5Jm4CGw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q13813 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351450|uniprotkb:Q13186|uniprotkb:Q15324|uniprotkb:Q16606|uniprotkb:Q59EF1|uniprotkb:Q5VXV5|uniprotkb:Q5VXV6|uniprotkb:Q7Z6M5|uniprotkb:Q9P0V0|intact:EBI-4404719|intact:EBI-28985930|ensembl:ENSP00000361816 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sptn1_human(display_long)|uniprotkb:SPTAN1(gene name)|psi-mi:SPTAN1(display_short)|uniprotkb:SPTA2(gene name synonym)|uniprotkb:Alpha-II spectrin(gene name synonym)|uniprotkb:Fodrin alpha chain(gene name synonym)|uniprotkb:NEAS(gene name synonym)|uniprotkb:Spectrin, non-erythroid alpha subunit(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001123910.1|refseq:NP_001182461.1|refseq:NP_003118.2|ensembl:ENSG00000197694(gene)|ensembl:ENST00000372731(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005829"(cytosol)|go:"GO:0008091"(spectrin)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0035580"(specific granule lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0051693"(actin filament capping)|go:"GO:0070062"(extracellular exosome)|go:"GO:1903561"(extracellular vesicle)|go:"GO:1904724"(tertiary granule lumen)|interpro:IPR001452(Src homology-3)|interpro:IPR002017(Spectrin repeat)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR014837(EF-hand, Ca insensitive)|interpro:IPR018159|interpro:IPR018247|interpro:IPR035825|interpro:IPR036028|mint:Q13813|rcsb pdb:2FOT|rcsb pdb:3F31|rcsb pdb:3FB2|rcsb pdb:5FW9|rcsb pdb:5FWB|rcsb pdb:5FWC|rcsb pdb:6ZEH|reactome:R-HSA-264870|reactome:R-HSA-373753|reactome:R-HSA-375165|reactome:R-HSA-445095|reactome:R-HSA-5673001|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9662360|reactome:R-HSA-9662361|ensembl:ENST00000358161|ensembl:ENSP00000350882|ensembl:ENSP00000361816|ensembl:ENST00000372739|ensembl:ENSP00000361824|dip:DIP-33141N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3d5XlsH+PSg32qNR/ZiooAJ/wH89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q12955 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2691178|uniprotkb:Q5VXD5|intact:EBI-7224084|intact:MINT-1182900|uniprotkb:Q13484|uniprotkb:B4DIL1|uniprotkb:E9PE32|uniprotkb:Q5CZH9|uniprotkb:Q7Z3G4|uniprotkb:B1AQT2|uniprotkb:Q9H0P5|ensembl:ENSP00000280772 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ank3_human(display_long)|uniprotkb:Ankyrin-G(gene name synonym)|uniprotkb:ANK3(gene name)|psi-mi:ANK3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSP00000280772|ensembl:ENST00000355288|ensembl:ENSP00000347436|ensembl:ENST00000373827|ensembl:ENSP00000362933|ensembl:ENST00000503366|ensembl:ENSP00000425236|refseq:NP_066267.2|refseq:NP_001191332.1|refseq:NP_001191333.1|refseq:NP_001140.2|ensembl:ENSG00000151150(gene)|ensembl:ENST00000280772(transcript)|go:"GO:0000281"(mitotic cytokinesis)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005764"(lysosome)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0007009"(plasma membrane organization)|go:"GO:0007165"(signal transduction)|go:"GO:0007409"(axonogenesis)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008093"(cytoskeletal anchor activity)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010650"(positive regulation of cell communication by electrical coupling)|go:"GO:0010765"(positive regulation of sodium ion transport)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014704"(intercalated disc)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016529"(sarcoplasmic reticulum)|go:"GO:0019228"(neuronal action potential)|go:"GO:0030018"(Z disc)|go:"GO:0030315"(T-tubule)|go:"GO:0030425"(dendrite)|go:"GO:0030507"(spectrin binding)|go:"GO:0030674"(protein-macromolecule adaptor activity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034112"(positive regulation of homotypic cell-cell adhesion)|go:"GO:0042383"(sarcolemma)|go:"GO:0043001"(Golgi to plasma membrane protein transport)|go:"GO:0043005"(neuron projection)|go:"GO:0043034"(costamere)|go:"GO:0043194"(axon initial segment)|go:"GO:0043266"(regulation of potassium ion transport)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045296"(cadherin binding)|go:"GO:0045838"(positive regulation of membrane potential)|go:"GO:0071286"(cellular response to magnesium ion)|go:"GO:0071709"(membrane assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0072660"(maintenance of protein location in plasma membrane)|go:"GO:0090314"(positive regulation of protein targeting to membrane)|go:"GO:0099612"(protein localization to axon)|go:"GO:1900827"(positive regulation of membrane depolarization during cardiac muscle cell action potential)|go:"GO:1902260"(negative regulation of delayed rectifier potassium channel activity)|go:"GO:2000651"(positive regulation of sodium ion transmembrane transporter activity)|go:"GO:2001259"(positive regulation of cation channel activity)|interpro:IPR000488(Death)|interpro:IPR000906(ZU5)|interpro:IPR002110(Ankyrin)|interpro:IPR011029(DEATH-like)|interpro:IPR020683|interpro:IPR036770|interpro:IPR037971|interpro:IPR040745|rcsb pdb:4O6X|reactome:R-HSA-445095|reactome:R-HSA-6807878|go:"GO:0005783"(endoplasmic reticulum)|dip:DIP-49017N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:k03Sz+VxForOlnJt8P9i8KAFzss9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q99848 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1048111|uniprotkb:Q96A66|ensembl:ENSP00000236051 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ebp2_human(display_long)|uniprotkb:EBNA1-binding protein 2(gene name synonym)|uniprotkb:Nucleolar protein p40(gene name synonym)|uniprotkb:EBNA1BP2(gene name)|psi-mi:EBNA1BP2(display_short)|uniprotkb:EBP2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001153408.1|refseq:NP_006815.2|ensembl:ENSG00000117395(gene)|ensembl:ENST00000236051(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0006364"(rRNA processing)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0034399"(nuclear periphery)|go:"GO:0042273"(ribosomal large subunit biogenesis)|interpro:IPR008610(Eukaryotic rRNA processing)|mint:Q99848|reactome:R-HSA-6791226 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lUFbxBko/pJHiNq8uuefmK3Xqp89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8TF72 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2622657|uniprotkb:Q9P247|uniprotkb:Q5QTQ3|uniprotkb:Q96IR9|uniprotkb:Q6ZRW3|ensembl:ENSP00000296043 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:shrm3_human(display_long)|uniprotkb:KIAA1481(gene name synonym)|uniprotkb:SHRML(gene name synonym)|uniprotkb:Shroom-related protein(gene name synonym)|uniprotkb:MSTP013(orf name)|uniprotkb:SHROOM3(gene name)|psi-mi:SHROOM3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_065910.3|ensembl:ENSG00000138771(gene)|ensembl:ENST00000296043(transcript)|go:"GO:0000902"(cell morphogenesis)|go:"GO:0001843"(neural tube closure)|go:"GO:0002064"(epithelial cell development)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005874"(microtubule)|go:"GO:0005912"(adherens junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007389"(pattern specification process)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0043296"(apical junction complex)|go:"GO:0043482"(cellular pigment accumulation)|go:"GO:0045176"(apical protein localization)|go:"GO:0051015"(actin filament binding)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR014799(Apx/shroom, ASD2)|interpro:IPR014800(Apx/shroom, ASD1)|interpro:IPR027685|interpro:IPR030494|interpro:IPR036034|mint:Q8TF72|rcsb pdb:6FBB|rcsb pdb:6FCP|ensembl:ENSP00000296043 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0MpUunWh5c6Wwa8ep6BgurgU8e89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q8IZ21 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3938822|uniprotkb:Q9H6X0|uniprotkb:Q8N384|uniprotkb:Q6NUN6|uniprotkb:Q9H8W6|uniprotkb:D3DPM3|uniprotkb:A2APK6|uniprotkb:Q9H395|uniprotkb:Q68DD4|uniprotkb:B9ZVW0|ensembl:ENSP00000362945 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:phar4_human(display_long)|uniprotkb:PHACTR4(gene name)|psi-mi:PHACTR4(display_short)|uniprotkb:PRO2963(orf name) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000204138(gene)|ensembl:ENST00000373839(transcript)|go:"GO:0001755"(neural crest cell migration)|go:"GO:0001843"(neural tube closure)|go:"GO:0003779"(actin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008157"(protein phosphatase 1 binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0043085"(positive regulation of catalytic activity)|go:"GO:0048484"(enteric nervous system development)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0061386"(closure of optic fissure)|go:"GO:0072542"(protein phosphatase activator activity)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|interpro:IPR004018(RPEL repeat)|interpro:IPR029984|refseq:NP_001041648.1|refseq:NP_076412.3|refseq:XP_016857657.1|refseq:XP_016857662.1|dip:DIP-47323N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:RaPU7amt8Ztkr4p8+PMGSs5Pw4I9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q658P3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3933105|uniprotkb:Q86SF6|uniprotkb:Q9NVB5|uniprotkb:A8K6E3|uniprotkb:Q8TF03|uniprotkb:Q8TDP3|uniprotkb:Q4VBR2|uniprotkb:Q8NEW6|uniprotkb:Q53SQ8|uniprotkb:Q7Z389|uniprotkb:Q4ZG36|ensembl:ENSP00000376818|ensembl:ENSP00000376819 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:stea3_human(display_long)|uniprotkb:STEAP3(gene name)|psi-mi:STEAP3(display_short)|uniprotkb:TSAP6(gene name synonym)|uniprotkb:Dudulin-2(gene name synonym)|uniprotkb:Six-transmembrane epithelial antigen of prostate 3(gene name synonym)|uniprotkb:Tumor suppressor-activated pathway protein 6(gene name synonym)|uniprotkb:pHyde(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011509705.1|refseq:NP_619543.2|ensembl:ENSG00000115107(gene)|ensembl:ENST00000393106(transcript)|ensembl:ENST00000393107(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005771"(multivesicular body)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008823"(cupric reductase activity)|go:"GO:0009306"(protein secretion)|go:"GO:0010008"(endosome membrane)|go:"GO:0015677"(copper ion import)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016723"(oxidoreductase activity, acting on metal ions, NAD or NADP as acceptor)|go:"GO:0033572"(transferrin transport)|go:"GO:0042802"(identical protein binding)|go:"GO:0046872"(metal ion binding)|go:"GO:0052851"("ferric-chelate reductase (NADPH) activity")|go:"GO:0055072"(iron ion homeostasis)|interpro:IPR013130(Ferric reductase-like transmembrane component, N-terminal)|interpro:IPR028939|interpro:IPR036291|rcsb pdb:2VNS|rcsb pdb:2VQ3|reactome:R-HSA-6803204|reactome:R-HSA-9013148|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9035034|reactome:R-HSA-917977|go:"GO:0006915"(apoptotic process)|refseq:NP_001008410.1|refseq:NP_060704.2|refseq:NP_878919.2|refseq:XP_006712677.1|refseq:XP_006712678.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:fZmXHidOHx0fIw1WYbsyliQcZVA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60437 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-368321|uniprotkb:O60314|uniprotkb:O60454|uniprotkb:Q14C98|intact:EBI-28977702|ensembl:ENSP00000340510 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pepl_human(display_long)|uniprotkb:PPL(gene name)|psi-mi:PPL(display_short)|uniprotkb:KIAA0568(gene name synonym)|uniprotkb:195 kDa cornified envelope precursor protein(gene name synonym)|uniprotkb:190 kDa paraneoplastic pemphigus antigen(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002696.3|ensembl:ENSP00000340510|ensembl:ENSG00000118898(gene)|ensembl:ENST00000345988(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0016020"(membrane)|go:"GO:0030057"(desmosome)|go:"GO:0031424"(keratinization)|go:"GO:0042060"(wound healing)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001101(Plectin repeat)|interpro:IPR001452(Src homology-3)|interpro:IPR018159|interpro:IPR035915|interpro:IPR041615|interpro:IPR043197|rcsb pdb:4Q28|reactome:R-HSA-6809371|reactome:R-HSA-8851680|go:"GO:0009612"(response to mechanical stimulus) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:z5hpIs1pxsIiWy8S7T5477iRVdg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q86W92 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1045582|uniprotkb:O75336|uniprotkb:Q86X70|uniprotkb:Q9NY03|uniprotkb:Q9ULJ0|ensembl:ENSP00000314724 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lipb1_human(display_long)|uniprotkb:Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1(gene name synonym)|uniprotkb:PPFIBP1(gene name)|psi-mi:PPFIBP1(display_short)|uniprotkb:KIAA1230(gene name synonym)|uniprotkb:hSGT2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000110841(gene)|ensembl:ENST00000318304(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0007155"(cell adhesion)|go:"GO:0007528"(neuromuscular junction development)|go:"GO:0045296"(cadherin binding)|go:"GO:0048786"(presynaptic active zone)|go:"GO:0050808"(synapse organization)|interpro:IPR001660(Sterile alpha motif SAM)|interpro:IPR013761(Sterile alpha motif-type)|interpro:IPR029515|interpro:IPR030437|interpro:IPR037617|interpro:IPR037618|interpro:IPR037619|mint:Q86W92|reactome:R-HSA-388844|refseq:NP_001185844.1|refseq:NP_001185845.1|refseq:NP_003613.3|refseq:NP_803193.2|dip:DIP-42195N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:PIoFJHaX4lvBJ0EYcascPgJP8bI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y446 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2880227|ensembl:ENSP00000331678|uniprotkb:F8J390|uniprotkb:Q53EX8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkp3_human(display_long)|uniprotkb:PKP3(gene name)|psi-mi:PKP3(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000184363(gene)|ensembl:ENST00000331563(transcript)|go:"GO:0002159"(desmosome assembly)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0006417"(regulation of translation)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0019899"(enzyme binding)|go:"GO:0030054"(cell junction)|go:"GO:0030057"(desmosome)|go:"GO:0001533"(cornified envelope)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1902373"(negative regulation of mRNA catabolic process)|go:"GO:1990124"(messenger ribonucleoprotein complex)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028434|interpro:IPR028435|mint:Q9Y446|reactome:R-HSA-6805567|reactome:R-HSA-6809371|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|refseq:NP_001289958.1|refseq:NP_009114.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:zGNbdze5MA5Mnf8m9IWZsxAPjAQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UHD8 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-851542|uniprotkb:Q96QF3|uniprotkb:Q96QF4|uniprotkb:Q96QF5|uniprotkb:Q9HA04|uniprotkb:Q9UG40|uniprotkb:Q9Y5W4|uniprotkb:A8K2V3|uniprotkb:B3KPM0|uniprotkb:B4DTL9|uniprotkb:B4E0N2|uniprotkb:B4E274|uniprotkb:B7Z654|ensembl:ENSP00000391249 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:sept9_human(display_long)|uniprotkb:SEPTIN9(gene name)|psi-mi:SEPTIN9(display_short)|uniprotkb:KIAA0991(gene name synonym)|uniprotkb:MLL septin-like fusion protein MSF-A(gene name synonym)|uniprotkb:MSF(gene name synonym)|uniprotkb:Ovarian/Breast septin(gene name synonym)|uniprotkb:SEPT9(gene name synonym)|uniprotkb:Septin D1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_006721706.1|refseq:XP_006721707.1|refseq:NP_001106963.1|refseq:NP_001106964.1|refseq:NP_001106965.1|refseq:NP_001106966.1|refseq:NP_001106967.1|refseq:NP_001106968.1|refseq:NP_006631.2|refseq:XP_016879520.1|refseq:XP_016879521.1|refseq:NP_001280624.1|refseq:NP_001280625.1|refseq:NP_001280626.1|refseq:NP_001280627.1|refseq:XP_011522509.1|refseq:XP_011522510.1|refseq:XP_005257019.1|dip:DIP-36697N|ensembl:ENSG00000184640(gene)|ensembl:ENST00000427177(transcript)|go:"GO:0001725"(stress fiber)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005874"(microtubule)|go:"GO:0005930"(axoneme)|go:"GO:0005940"(septin ring)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0015630"(microtubule cytoskeleton)|go:"GO:0031105"(septin complex)|go:"GO:0032153"(cell division site)|go:"GO:0034613"(cellular protein localization)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0061640"(cytoskeleton-dependent cytokinesis)|go:"GO:0097730"(non-motile cilium)|go:"GO:1902857"(positive regulation of non-motile cilium assembly)|interpro:IPR016491(Septin)|interpro:IPR027417|interpro:IPR030379|interpro:IPR030645|mint:Q9UHD8|rcsb pdb:4YQF|rcsb pdb:5CYO|rcsb pdb:5CYP - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:YzUn6hS5tAX/U+SJ8YzqzWW/dQI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9Y2H5 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1171228|uniprotkb:A7MD51|uniprotkb:Q5VTI6|intact:EBI-28984932|ensembl:ENSP00000272203 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pkha6_human(display_long)|uniprotkb:PLEKHA6(gene name)|psi-mi:PLEKHA6(display_short)|uniprotkb:KIAA0969(gene name synonym)|uniprotkb:PEPP3(gene name synonym)|uniprotkb:Phosphoinositol 3-phosphate-binding protein 3(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_005245025.2|refseq:NP_055750.2|ensembl:ENSP00000272203|ensembl:ENSG00000143850(gene)|ensembl:ENST00000272203(transcript)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR040392|rcsb pdb:2D9Y|rcsb pdb:2YRY|reactome:R-HSA-1660499|interpro:IPR001849(Pleckstrin-like) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:f0GIuTpkkEErro4SoWhKwmsIjuw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O00161 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-745000|uniprotkb:O00162|uniprotkb:Q13602|uniprotkb:Q6IAE3|ensembl:ENSP00000249647 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snp23_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-23(gene name synonym)|uniprotkb:SNAP23(gene name)|psi-mi:SNAP23(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_003816.2|refseq:NP_570710.1|ensembl:ENSG00000092531(gene)|ensembl:ENST00000249647(transcript)|go:"GO:0002553"(histamine secretion by mast cell)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006887"(exocytosis)|go:"GO:0006892"(post-Golgi vesicle-mediated transport)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0019905"(syntaxin binding)|go:"GO:0030670"(phagocytic vesicle membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035579"(specific granule membrane)|go:"GO:0042581"(specific granule)|go:"GO:0042582"(azurophil granule)|go:"GO:0043005"(neuron projection)|go:"GO:0061025"(membrane fusion)|go:"GO:0070062"(extracellular exosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|interpro:IPR000928(SNAP-25)|mint:O00161|rcsb pdb:1NHL|rcsb pdb:3ZUS|reactome:R-HSA-1445148|reactome:R-HSA-199992|reactome:R-HSA-6798695|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|reactome:R-HSA-1236974 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:8ZcXbqhusSijGdekDMdkZA5DejY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NZC7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4320739|uniprotkb:A8K323|uniprotkb:Q5MYT5|uniprotkb:Q96KM3|uniprotkb:Q96RF2|uniprotkb:Q9BTT8|uniprotkb:Q9NPC9|uniprotkb:Q9NRF4|uniprotkb:Q9NRF5|uniprotkb:Q9NRF6|uniprotkb:Q9NRK1|uniprotkb:Q9NZC5|ensembl:ENSP00000457230 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:wwox_human(display_long)|uniprotkb:WWOX(gene name)|psi-mi:WWOX(display_short)|uniprotkb:FOR(gene name synonym)|uniprotkb:WOX1(gene name synonym)|uniprotkb:Fragile site FRA16D oxidoreductase(gene name synonym)|uniprotkb:SDR41C1(gene name synonym)|uniprotkb:Short chain dehydrogenase/reductase family 41C member 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_057457.1|refseq:NP_570607.1|refseq:NP_001278926.1|ensembl:ENST00000566780(transcript)|go:"GO:0001649"(osteoblast differentiation)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016491"(oxidoreductase activity)|go:"GO:0019899"(enzyme binding)|go:"GO:0030178"(negative regulation of Wnt signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048705"(skeletal system morphogenesis)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0072332"(intrinsic apoptotic signaling pathway by p53 class mediator)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:2001238"(positive regulation of extrinsic apoptotic signaling pathway)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR002347(Glucose/ribitol dehydrogenase)|interpro:IPR036020|interpro:IPR036291|interpro:IPR042732|mint:Q9NZC7|rcsb pdb:1WMV|reactome:R-HSA-1251985|reactome:R-HSA-8866904|reactome:R-HSA-8866907|ensembl:ENSG00000186153(gene) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:YMGESSlld4QIPoFrcPX3zhwIy2E9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95372 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-715999|uniprotkb:Q7Z4Z2|ensembl:ENSP00000363638 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:lypa2_human(display_long)|uniprotkb:Lysophospholipase II(gene name synonym)|uniprotkb:LYPLA2(gene name)|psi-mi:LYPLA2(display_short)|uniprotkb:APT2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_009191.1|ensembl:ENSG00000011009(gene)|ensembl:ENST00000374514(transcript)|go:"GO:0002084"(protein depalmitoylation)|go:"GO:0004622"(lysophospholipase activity)|go:"GO:0005737"(cytoplasm)|go:"GO:0005795"(Golgi stack)|go:"GO:0005829"(cytosol)|go:"GO:0006631"(fatty acid metabolic process)|go:"GO:0007411"(axon guidance)|go:"GO:0008474"("palmitoyl-(protein) hydrolase activity")|go:"GO:0045296"(cadherin binding)|go:"GO:0046464"(acylglycerol catabolic process)|go:"GO:0052689"(carboxylic ester hydrolase activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1905344"(prostaglandin catabolic process)|interpro:IPR003140(Phospholipase/carboxylesterase)|interpro:IPR029058|rcsb pdb:5SYN|rcsb pdb:6BJE|reactome:R-HSA-373760 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yJ0IGnOIc6UvuzuLdZb8WzlN9aY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P31949 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-701862|uniprotkb:Q5VTK0|ensembl:ENSP00000271638 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:s10ab_human(display_long)|uniprotkb:S100 calcium-binding protein A11(gene name synonym)|uniprotkb:Calgizzarin(gene name synonym)|uniprotkb:Metastatic lymph node gene 70 protein(gene name synonym)|uniprotkb:S100A11(gene name)|psi-mi:S100A11(display_short)|uniprotkb:MLN70(gene name synonym)|uniprotkb:S100C(gene name synonym)|uniprotkb:Protein S100-C(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005611.1|ensembl:ENSG00000163191(gene)|ensembl:ENST00000271638(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007165"(signal transduction)|go:"GO:0008156"(negative regulation of DNA replication)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0014911"(positive regulation of smooth muscle cell migration)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0048306"(calcium-dependent protein binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR001751(S100/CaBP-9k-type, calcium binding)|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR013787(S100/CaBP-9k-type, calcium binding, subdomain)|interpro:IPR018247|interpro:IPR028482|mint:P31949|rcsb pdb:1V4Z|rcsb pdb:1V50|rcsb pdb:2LUC|reactome:R-HSA-6798695 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:BG1iIxIcMpumVbd2yTJwB5gy4VU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q02878 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-359655|uniprotkb:Q2M3Q3|uniprotkb:Q8WW97|ensembl:ENSP00000202773|ensembl:ENSP00000403172 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl6_human(display_long)|uniprotkb:RPL6(gene name)|psi-mi:RPL6(display_short)|uniprotkb:TXREB1(gene name synonym)|uniprotkb:Tax-responsive enhancer element-binding protein 107(gene name synonym)|uniprotkb:Neoplasm-related protein C140(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL6(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000961.2|refseq:NP_001019833.1|ensembl:ENSG00000089009(gene)|ensembl:ENST00000202773(transcript)|ensembl:ENST00000424576(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005791"(rough endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR000915(Ribosomal protein L6E)|interpro:IPR005568(Ribosomal protein L6, N-terminal)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR041997|mint:Q02878|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001307066.1|refseq:NP_001307067.1|refseq:NP_001307068.1|refseq:NP_001307069.1|refseq:NP_001307070.1|refseq:XP_016875270.1|refseq:XP_016875271.1|dip:DIP-27547N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Y7fx3ToInzucV2QmI8KLSdHxai09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P55196 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-365875|uniprotkb:O75089|uniprotkb:Q5TIG6|uniprotkb:O75087|uniprotkb:O75088|uniprotkb:Q9NSN7|uniprotkb:Q9NU92|uniprotkb:Q5TIG7|uniprotkb:Q59FP0|ensembl:ENSP00000404595 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:afad_human(display_long)|uniprotkb:AFDN(gene name)|psi-mi:AFDN(display_short)|uniprotkb:AF6(gene name synonym)|uniprotkb:ALL1-fused gene from chromosome 6 protein(gene name synonym)|uniprotkb:Afadin adherens junction formation factor(gene name synonym)|uniprotkb:MLLT4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001035089.1|refseq:NP_001193937.1|refseq:XP_005267053.1|ensembl:ENST00000392108|ensembl:ENSP00000375956|ensembl:ENST00000392112|ensembl:ENSP00000375960|ensembl:ENST00000400822|ensembl:ENSP00000383623|ensembl:ENSP00000404595|refseq:NP_001278893.1|ensembl:ENSG00000130396(gene)|ensembl:ENST00000447894(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007267"(cell-cell signaling)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032880"(regulation of protein localization)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0046930"(pore complex)|go:"GO:0046931"(pore complex assembly)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051015"(actin filament binding)|go:"GO:0061951"(establishment of protein localization to plasma membrane)|go:"GO:0070160"(tight junction)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|interpro:IPR000159(Ras-association)|interpro:IPR000253(Forkhead-associated)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR002710(Dilute)|interpro:IPR008984(SMAD/FHA domain)|interpro:IPR029071|interpro:IPR036034|interpro:IPR037977|mint:P55196|rcsb pdb:1T2M|rcsb pdb:1XZ9|rcsb pdb:2AIN|rcsb pdb:2EXG|rcsb pdb:5A6C|reactome:R-HSA-418990|go:"GO:0022409"(positive regulation of cell-cell adhesion) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:x7kK5K1+wAFZFdVopvQ/l496J5U9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14156 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1049330|uniprotkb:Q2VPK2|uniprotkb:Q63HL7|uniprotkb:Q68DX1|uniprotkb:Q6IQ18|uniprotkb:A7MD19|ensembl:ENSP00000254624 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:efr3a_human(display_long)|uniprotkb:KIAA0143(gene name synonym)|uniprotkb:Protein EFR3-like(gene name synonym)|uniprotkb:EFR3A(gene name)|psi-mi:EFR3A(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_055952.2|refseq:NP_001310482.1|refseq:NP_001310483.1|refseq:NP_001310484.1|refseq:NP_001310485.1|refseq:NP_001310486.1|refseq:NP_001310487.1|ensembl:ENSG00000132294(gene)|ensembl:ENST00000254624(transcript)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0046854"(phosphatidylinositol phosphate biosynthetic process)|go:"GO:0072659"(protein localization to plasma membrane)|interpro:IPR016024(Armadillo-type fold) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WWG8LKAY6O+CbAZdUzEZeo4wUc09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:A7KAX9 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-308663|uniprotkb:Q86YL6|intact:EBI-1210177|uniprotkb:O94820|uniprotkb:Q8IUG4|uniprotkb:Q9BWG3|ensembl:ENSP00000310561|uniprotkb:I7H0B0 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rhg32_human(display_long)|uniprotkb:ARHGAP32(gene name)|psi-mi:ARHGAP32(display_short)|uniprotkb:GRIT(gene name synonym)|uniprotkb:KIAA0712(gene name synonym)|uniprotkb:RICS(gene name synonym)|uniprotkb:Brain-specific Rho GTPase-activating protein(gene name synonym)|uniprotkb:GAB-associated Cdc42/Rac GTPase-activating protein(gene name synonym)|uniprotkb:GC-GAP(gene name synonym)|uniprotkb:GTPase regulator interacting with TrkA(gene name synonym)|uniprotkb:Rho-type GTPase-activating protein 32(gene name synonym)|uniprotkb:Rho/Cdc42/Rac GTPase-activating protein RICS(gene name synonym)|uniprotkb:RhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling(gene name synonym)|uniprotkb:p200RhoGAP(gene name synonym)|uniprotkb:p250GAP(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0005938"(cell cortex)|ensembl:ENSP00000310561|ensembl:ENST00000392657|ensembl:ENSP00000376425|ensembl:ENST00000527272|ensembl:ENSP00000432862|ensembl:ENSG00000134909(gene)|ensembl:ENST00000310343(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001650"(fibrillar center)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0010008"(endosome membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0043197"(dendritic spine)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1901981"(phosphatidylinositol phosphate binding)|interpro:IPR000198(RhoGAP)|interpro:IPR001452(Src homology-3)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR036028|interpro:IPR036871|interpro:IPR042139|mint:A7KAX9|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013405|reactome:R-HSA-9013406|reactome:R-HSA-9013408|reactome:R-HSA-9013409|reactome:R-HSA-9013423|reactome:R-HSA-9035034|rcsb pdb:3IUG|refseq:NP_001136157.1|refseq:NP_055530.2|go:"GO:0007264"(small GTPase mediated signal transduction) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:V51KfHcAYYMGvIsWaG5hNqZ49Yk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q7KZI7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-516560|uniprotkb:Q15449|uniprotkb:Q15524|uniprotkb:Q5XGA3|uniprotkb:Q68A18|uniprotkb:Q96HB3|uniprotkb:Q96RG0|ensembl:ENSP00000385751 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mark2_human(display_long)|uniprotkb:MAP/microtubule affinity-regulating kinase 2(gene name synonym)|uniprotkb:ELKL motif kinase 1(gene name synonym)|uniprotkb:PAR1 homolog(gene name synonym)|uniprotkb:MARK2(gene name)|psi-mi:MARK2(display_short)|uniprotkb:EMK1(gene name synonym)|uniprotkb:PAR1 homolog b(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001034558.2|refseq:NP_001156768.1|refseq:NP_001156769.1|refseq:NP_004945.4|refseq:NP_059672.2|dip:DIP-31321N|ensembl:ENSG00000072518(gene)|ensembl:ENST00000402010(transcript)|go:"GO:0000226"(microtubule cytoskeleton organization)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0000422"(autophagy of mitochondrion)|go:"GO:0001764"(neuron migration)|go:"GO:0003723"(RNA binding)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008289"(lipid binding)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048156"(tau protein binding)|go:"GO:0050321"(tau-protein kinase activity)|go:"GO:0050770"(regulation of axonogenesis)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0010976"(positive regulation of neuron projection development)|go:"GO:0016020"(membrane)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0018107"(peptidyl-threonine phosphorylation)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0030295"(protein kinase activator activity)|go:"GO:0030425"(dendrite)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0051646"(mitochondrion localization)|go:"GO:0061564"(axon development)|go:"GO:0070507"(regulation of microtubule cytoskeleton organization)|go:"GO:0071963"(establishment or maintenance of cell polarity regulating cell shape)|go:"GO:0097427"(microtubule bundle)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1904526"(regulation of microtubule binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001772(Kinase-associated KA1)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR015940(Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR028375|mint:Q7KZI7|rcsb pdb:3IEC|rcsb pdb:5EAK|rcsb pdb:5KZ7|rcsb pdb:5KZ8 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:yfUqSCu4bgkncBd6hRRg5pKkArc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O00151 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-724897|uniprotkb:Q5VZH5|uniprotkb:Q9BPZ9|uniprotkb:B2RBS6|ensembl:ENSP00000360305 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:pdli1_human(display_long)|uniprotkb:Elfin(gene name synonym)|uniprotkb:LIM domain protein CLP-36(gene name synonym)|uniprotkb:C-terminal LIM domain protein 1(gene name synonym)|uniprotkb:PDLIM1(gene name)|psi-mi:PDLIM1(display_short)|uniprotkb:CLIM1(gene name synonym)|uniprotkb:CLP36(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_066272.1|go:"GO:0003779"(actin binding)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005912"(adherens junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0006357"(regulation of transcription by RNA polymerase II)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0007507"(heart development)|go:"GO:0010761"(fibroblast migration)|go:"GO:0030011"(maintenance of cell polarity)|go:"GO:0030018"(Z disc)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030950"(establishment or maintenance of actin cytoskeleton polarity)|go:"GO:0031941"(filamentous actin)|go:"GO:0043149"(stress fiber assembly)|go:"GO:0046872"(metal ion binding)|go:"GO:0051371"(muscle alpha-actinin binding)|go:"GO:0061061"(muscle structure development)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001781(Zinc finger, LIM-type)|ensembl:ENSG00000107438(gene)|interpro:IPR006643(ZASP)|interpro:IPR028537|interpro:IPR031847|interpro:IPR036034|rcsb pdb:1X62|rcsb pdb:2PKT|ensembl:ENST00000329399(transcript)|go:"GO:0001666"(response to hypoxia)|go:"GO:0001725"(stress fiber)|go:"GO:0003713"(transcription coactivator activity) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:kUUqX2NgmaXbdbESj6oHxE+EQ2g9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P49757 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-915016|uniprotkb:Q6NUQ7|uniprotkb:Q86SY1|uniprotkb:Q8WW73|uniprotkb:Q9UBG1|uniprotkb:Q9UEQ4|uniprotkb:Q9UKE8|uniprotkb:Q9UKE9|uniprotkb:Q9UKF0|uniprotkb:Q9UQJ4|uniprotkb:B4E2B1|uniprotkb:B1P2N7|uniprotkb:B1P2N8|uniprotkb:B1P2N9|uniprotkb:B1P2N5|uniprotkb:B1P2N6|intact:EBI-28966915|ensembl:ENSP00000347169|ensembl:ENSP00000451300 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:numb_human(display_long)|uniprotkb:Protein S171(gene name synonym)|uniprotkb:NUMB(gene name)|psi-mi:NUMB(display_short)|uniprotkb:C14orf41(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000554521|ensembl:ENSP00000450817|ensembl:ENST00000554546|ensembl:ENSP00000452416|ensembl:ENSP00000451300|ensembl:ENST00000555394|ensembl:ENSP00000451625|ensembl:ENST00000555738|ensembl:ENSP00000452069|ensembl:ENST00000557597|ensembl:ENSP00000451117|ensembl:ENST00000559312|ensembl:ENSP00000452888|ensembl:ENST00000560335|ensembl:ENSP00000453209|ensembl:ENSP00000347169|ensembl:ENST00000356296|ensembl:ENSP00000348644|ensembl:ENST00000359560|ensembl:ENSP00000352563|ensembl:ENST00000535282|ensembl:ENSP00000441258|ensembl:ENST00000544991|ensembl:ENSP00000446001|refseq:NP_001307043.1|refseq:NP_001005743.1|refseq:NP_001005744.1|refseq:NP_001005745.1|refseq:NP_003735.3|dip:DIP-37981N|ensembl:ENSG00000133961(gene)|ensembl:ENST00000355058(transcript)|ensembl:ENST00000555238(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010008"(endosome membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0019897"(extrinsic component of plasma membrane)|go:"GO:0021670"(lateral ventricle development)|go:"GO:0021849"(neuroblast division in subventricular zone)|go:"GO:0030136"(clathrin-coated vesicle)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0034332"(adherens junction organization)|go:"GO:0045177"(apical part of cell)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0050769"(positive regulation of neurogenesis)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|go:"GO:1903077"(negative regulation of protein localization to plasma membrane)|interpro:IPR006020(Phosphotyrosine interaction region)|interpro:IPR010449(NUMB phenylalanine-rich)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR016698(Numb/numb-like)|mint:P49757|rcsb pdb:5NJJ|rcsb pdb:5NJK|reactome:R-HSA-2122948|reactome:R-HSA-437239|reactome:R-HSA-5610780|reactome:R-HSA-5632684 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:X+CHBhp67o6ROnf86RCtXlCAaF49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9NWB6 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2808785|uniprotkb:B4E0Y3|uniprotkb:Q6IQ34|uniprotkb:Q5T257|ensembl:ENSP00000383059 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:argl1_human(display_long)|uniprotkb:ARGLU1(gene name)|psi-mi:ARGLU1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_060481.3|ensembl:ENSG00000134884(gene)|ensembl:ENST00000400198(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0045296"(cadherin binding)|interpro:IPR033371 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:tZ/PMMjPF72fu4NqFOfhHWB0QWM9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P08195 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-702356|uniprotkb:Q13543|ensembl:ENSP00000367122 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:4f2_human(display_long)|uniprotkb:Lymphocyte activation antigen 4F2 large subunit(gene name synonym)|uniprotkb:4F2 heavy chain antigen(gene name synonym)|uniprotkb:SLC3A2(gene name)|psi-mi:SLC3A2(display_short)|uniprotkb:MDU1(gene name synonym)|uniprotkb:Solute carrier family 3 member 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001012680.1|refseq:NP_001012682.1|refseq:NP_001013269.1|refseq:NP_002385.3|ensembl:ENSG00000168003(gene)|ensembl:ENST00000377890(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0003824"(catalytic activity)|go:"GO:0005432"("calcium:sodium antiporter activity")|go:"GO:0005654"(nucleoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005975"(carbohydrate metabolic process)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006865"(amino acid transport)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0015173"(aromatic amino acid transmembrane transporter activity)|go:"GO:0015175"(neutral amino acid transmembrane transporter activity)|go:"GO:0015180"(L-alanine transmembrane transporter activity)|go:"GO:0015190"(L-leucine transmembrane transporter activity)|go:"GO:0015820"(leucine transport)|go:"GO:0015823"(phenylalanine transport)|go:"GO:0015827"(tryptophan transport)|go:"GO:0016020"(membrane)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0042470"(melanosome)|go:"GO:0043330"(response to exogenous dsRNA)|go:"GO:0044225"(apical pole of neuron)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0046718"(viral entry into host cell)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098713"(leucine import across plasma membrane)|go:"GO:1903801"(L-leucine import across plasma membrane)|go:"GO:1904273"(L-alanine import across plasma membrane)|go:"GO:1990184"(amino acid transport complex)|interpro:IPR006047(Glycosyl hydrolase, family 13, catalytic region)|interpro:IPR013780(Glycosyl hydrolase, family 13, all-beta)|interpro:IPR017853(Glycoside hydrolase, catalytic core)|interpro:IPR031984|interpro:IPR042280|mint:P08195|rcsb pdb:2DH2|rcsb pdb:2DH3|rcsb pdb:6IRS|rcsb pdb:6IRT|rcsb pdb:6JMQ|rcsb pdb:6JMR|rcsb pdb:6S8V|rcsb pdb:7CCS|reactome:R-HSA-210991|reactome:R-HSA-352230|reactome:R-HSA-5660862|reactome:R-HSA-71240 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+7lJ/35nXzIs8SLCor0Vh5fAZYQ9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96C19 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-4290759|uniprotkb:Q5JYW9|ensembl:ENSP00000365147 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:efhd2_human(display_long)|uniprotkb:EFHD2(gene name)|psi-mi:EFHD2(display_short)|uniprotkb:SWS1(gene name synonym)|uniprotkb:Swiprosin-1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_077305.2|interpro:IPR002048(Calcium-binding EF-hand)|interpro:IPR011992(EF-Hand type)|interpro:IPR040365|mint:Q96C19|rcsb pdb:5H0P|rcsb pdb:5I2L|rcsb pdb:5I2O|rcsb pdb:5I2Q|reactome:R-HSA-9013405|go:"GO:0045296"(cadherin binding)|ensembl:ENSG00000142634(gene)|ensembl:ENST00000375980(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0045121"(membrane raft) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XBEoBjyjLxPn5MvaBph9sdsgdLk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O95721 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-490676|ensembl:ENSP00000215730 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:snp29_human(display_long)|uniprotkb:Vesicle-membrane fusion protein SNAP-29(gene name synonym)|uniprotkb:Soluble 29 kDa NSF attachment protein(gene name synonym)|uniprotkb:SNAP29(gene name)|psi-mi:SNAP29(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_004773.1|ensembl:ENSG00000099940(gene)|ensembl:ENST00000215730(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000421"(autophagosome membrane)|go:"GO:0005484"(SNAP receptor activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005776"(autophagosome)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006887"(exocytosis)|go:"GO:0006903"(vesicle targeting)|go:"GO:0006906"(vesicle fusion)|go:"GO:0015031"(protein transport)|go:"GO:0016082"(synaptic vesicle priming)|go:"GO:0016240"(autophagosome membrane docking)|go:"GO:0019905"(syntaxin binding)|go:"GO:0020018"(ciliary pocket membrane)|go:"GO:0031201"(SNARE complex)|go:"GO:0031629"(synaptic vesicle fusion to presynaptic active zone membrane)|go:"GO:0035577"(azurophil granule membrane)|go:"GO:0060271"(cilium assembly)|go:"GO:0061025"(membrane fusion)|go:"GO:0097352"(autophagosome maturation)|go:"GO:0098793"(presynapse)|interpro:IPR000727(Target SNARE coiled-coil region)|mint:O95721|rcsb pdb:4WY4|rcsb pdb:7BV6|reactome:R-HSA-6798695|reactome:R-HSA-6811438|dip:DIP-56475N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:4HyjERPnEDdBgiGt70N9oyrMN1k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P61927 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2105843|uniprotkb:P02403|uniprotkb:Q6IBB4|uniprotkb:Q99883|uniprotkb:B2R4H2|ensembl:ENSP00000274242 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl37_human(display_long)|uniprotkb:Large ribosomal subunit protein eL37(gene name synonym)|uniprotkb:RPL37(gene name)|psi-mi:RPL37(display_short)|uniprotkb:G1.16(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_000988.1|ensembl:ENSG00000145592(gene)|ensembl:ENST00000274242(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045202"(synapse)|go:"GO:0046872"(metal ion binding)|go:"GO:0097371"(MDM2/MDM4 family protein binding)|go:"GO:1901798"(positive regulation of signal transduction by p53 class mediator)|go:"GO:1990948"(ubiquitin ligase inhibitor activity)|interpro:IPR001569(Ribosomal protein L37e)|interpro:IPR011331(Ribosomal protein L37ae/L37e, core)|interpro:IPR011332(Ribosomal protein, zinc-binding)|interpro:IPR018267|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:0WNZ8lgxYeW91kmXUr2VQG1ULZw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P11171 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-1050906|uniprotkb:P11176|uniprotkb:Q14245|uniprotkb:Q5TB35|uniprotkb:Q5VXN8|uniprotkb:Q8IXV9|uniprotkb:Q9Y578|uniprotkb:Q9Y579|uniprotkb:B1ALH8|uniprotkb:B1ALH9|uniprotkb:D3DPM9|uniprotkb:D3DPN0|ensembl:ENSP00000345259|ensembl:ENSP00000362904 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:epb41_human(display_long)|uniprotkb:Band 4.1(gene name synonym)|uniprotkb:EPB4.1(gene name synonym)|uniprotkb:4.1R(gene name synonym)|uniprotkb:EPB41(gene name)|psi-mi:EPB41(display_short)|uniprotkb:E41P(gene name synonym)|uniprotkb:Erythrocyte membrane protein band 4.1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001159477.1|refseq:NP_001159478.1|refseq:NP_004428.1|refseq:NP_976217.1|refseq:XP_016856078.1|refseq:XP_005245818.1|refseq:XP_005245821.1|ensembl:ENSG00000159023(gene)|ensembl:ENST00000343067(transcript)|ensembl:ENST00000373798(transcript)|go:"GO:0003779"(actin binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005545"(1-phosphatidylinositol binding)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0007049"(cell cycle)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014069"(postsynaptic density)|go:"GO:0014731"(spectrin-associated cytoskeleton)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030054"(cell junction)|go:"GO:0030507"(spectrin binding)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032092"(positive regulation of protein binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0045171"(intercellular bridge)|go:"GO:0047485"(protein N-terminus binding)|go:"GO:0051219"(phosphoprotein binding)|go:"GO:0051301"(cell division)|go:"GO:0051924"(regulation of calcium ion transport)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0072686"(mitotic spindle)|go:"GO:0099738"(cell cortex region)|go:"GO:1904478"(regulation of intestinal absorption)|go:"GO:1904778"(positive regulation of protein localization to cell cortex)|interpro:IPR000299(Band 4.1, N-terminal)|interpro:IPR000798(Ezrin/radixin/moesin ERM)|interpro:IPR007477(SAB)|interpro:IPR008379(Band 4.1, C-terminal)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR014352(FERM/acyl-CoA-binding protein, 3-helical bundle)|interpro:IPR014847("FERM adjacent (FA)")|interpro:IPR018979|interpro:IPR018980|interpro:IPR019747|interpro:IPR019748|interpro:IPR019749|interpro:IPR021187|interpro:IPR029071|interpro:IPR035963|mint:P11171|rcsb pdb:1GG3|rcsb pdb:2RQ1|rcsb pdb:3QIJ|reactome:R-HSA-6794361|dip:DIP-17032N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZCaM+kjScfGP23wRkFRwVyxOyvk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9ULH7 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-493007|uniprotkb:A6ND53|uniprotkb:Q68CT1|uniprotkb:Q6UB16|uniprotkb:Q86WW2|uniprotkb:Q8N226|uniprotkb:B4DGT8|intact:EBI-28976812 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:mrtfb_human(display_long)|uniprotkb:MRTFB(gene name)|psi-mi:MRTFB(display_short)|uniprotkb:KIAA1243(gene name synonym)|uniprotkb:MKL/myocardin-like protein 2(gene name synonym)|uniprotkb:MKL2(gene name synonym)|uniprotkb:Megakaryoblastic leukemia 2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_006720977.1|refseq:NP_054767.3|interpro:IPR004018(RPEL repeat)|interpro:IPR003034(DNA-binding SAP)|ensembl:ENST00000318282|ensembl:ENSP00000339086|ensembl:ENSG00000186260|ensembl:ENST00000571589|ensembl:ENSP00000459626|ensembl:ENST00000573051|ensembl:ENSP00000460589|ensembl:ENST00000574045|ensembl:ENSP00000459205|refseq:NP_001295071.1|refseq:XP_011520870.1|interpro:IPR043451|refseq:XP_005255512.1|refseq:XP_005255509.1|refseq:XP_005255510.1|refseq:XP_006720971.1|refseq:XP_006720972.1|refseq:XP_016878990.1|refseq:XP_016878991.1|mint:Q9ULH7|interpro:IPR036361|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0007517"(muscle organ development)|go:"GO:0045296"(cadherin binding)|go:"GO:0045844"(positive regulation of striated muscle tissue development)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051145"(smooth muscle cell differentiation) - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:FEDyi3ECPX5T1KSwNjOZ/lWG1RY9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P26232 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3953920|uniprotkb:B3KXE5|uniprotkb:B7Z2W7|uniprotkb:B7Z352|uniprotkb:B7Z898|uniprotkb:Q4ZFW1|uniprotkb:Q53R26|uniprotkb:Q53R33|uniprotkb:Q53T67|uniprotkb:Q53T71|uniprotkb:Q53TM8|uniprotkb:Q7Z3L1|uniprotkb:Q7Z3Y0|ensembl:ENSP00000384638 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ctna2_human(display_long)|uniprotkb:CTNNA2(gene name)|psi-mi:CTNNA2(display_short)|uniprotkb:CAPR(gene name synonym)|uniprotkb:Alpha N-catenin(gene name synonym)|uniprotkb:Alpha-catenin-related protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001269526.1|refseq:NP_001269527.1|refseq:NP_001269528.1|refseq:NP_001269529.1|refseq:XP_011530857.1|refseq:XP_011530858.1|refseq:NP_001158355.1|refseq:NP_004380.2|ensembl:ENSG00000066032(gene)|ensembl:ENST00000402739(transcript)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005912"(adherens junction)|go:"GO:0007409"(axonogenesis)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0010975"(regulation of neuron projection development)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0021942"(radial glia guided migration of Purkinje cell)|go:"GO:0030424"(axon)|go:"GO:0034316"(negative regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0045296"(cadherin binding)|go:"GO:0048813"(dendrite morphogenesis)|go:"GO:0048854"(brain morphogenesis)|go:"GO:0051015"(actin filament binding)|go:"GO:0051823"(regulation of synapse structural plasticity)|go:"GO:0060134"(prepulse inhibition)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:2001222"(regulation of neuron migration)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030046|interpro:IPR036723|rcsb pdb:6DUW|reactome:R-HSA-525793|go:"GO:0005829"(cytosol)|refseq:NP_001307739.1|refseq:XP_016858892.1|dip:DIP-60979N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:Ms14mzGAhm356B/enTGIoPN5L5s9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q07157 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-79553|uniprotkb:B4E3K1|ensembl:ENSP00000281537|ensembl:ENSP00000484535|uniprotkb:Q2NKP3|uniprotkb:Q4ZGJ6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:zo1_human(display_long)|uniprotkb:TJP1(gene name)|psi-mi:TJP1(display_short)|uniprotkb:ZO1(gene name synonym)|uniprotkb:Zonula occludens protein 1(gene name synonym)|uniprotkb:Zona occludens protein 1(gene name synonym)|uniprotkb:Tight junction protein 1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000104067(gene)|ensembl:ENSG00000277401(gene)|ensembl:ENST00000346128(transcript)|go:"GO:0002102"(podosome)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0005921"(gap junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0030054"(cell junction)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0031032"(actomyosin structure organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034334"(adherens junction maintenance)|go:"GO:0035633"(maintenance of blood-brain barrier)|go:"GO:0042995"(cell projection)|go:"GO:0043066"(negative regulation of apoptotic process)|ensembl:ENST00000621049(transcript)|go:"GO:0043296"(apical junction complex)|go:"GO:0045177"(apical part of cell)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0051493"(regulation of cytoskeleton organization)|go:"GO:0051497"(negative regulation of stress fiber assembly)|go:"GO:0070160"(tight junction)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090557"(establishment of endothelial intestinal barrier)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0150105"(protein localization to cell-cell junction)|go:"GO:1901888"(regulation of cell junction assembly)|go:"GO:1902396"(protein localization to bicellular tight junction)|go:"GO:1903672"(positive regulation of sprouting angiogenesis)|go:"GO:1905605"(positive regulation of blood-brain barrier permeability)|go:"GO:2000049"(positive regulation of cell-cell adhesion mediated by cadherin)|go:"GO:2000250"(negative regulation of actin cytoskeleton reorganization)|go:"GO:2000810"(regulation of bicellular tight junction assembly)|interpro:IPR000906(ZU5)|interpro:IPR001452(Src homology-3)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR005417(Zona occludens protein)|interpro:IPR005418(Zona occludens protein ZO-1)|interpro:IPR008144(Guanylate kinase)|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR027417|interpro:IPR036028|interpro:IPR035597|interpro:IPR036034|mint:Q07157|rcsb pdb:2H2B|rcsb pdb:2H2C|rcsb pdb:2H3M|rcsb pdb:2JWE|rcsb pdb:2KXR|rcsb pdb:2KXS|rcsb pdb:2RCZ|rcsb pdb:3CYY|rcsb pdb:3LH5|rcsb pdb:3SHU|rcsb pdb:3SHW|rcsb pdb:3TSV|rcsb pdb:3TSW|rcsb pdb:3TSZ|rcsb pdb:4OEO|rcsb pdb:4OEP|rcsb pdb:4Q2Q|rcsb pdb:4YYX|reactome:R-HSA-191650|reactome:R-HSA-2028269|reactome:R-HSA-351906|reactome:R-HSA-8935964|refseq:NP_003248.3|refseq:NP_783297.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:/Yi7U3TcH6kPu4A/bQ5Nj0QeU2w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P05783 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-297888|uniprotkb:Q53G38|uniprotkb:Q5U0N8|uniprotkb:Q9BW26|ensembl:ENSP00000373487|ensembl:ENSP00000373489 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:k1c18_human(display_long)|uniprotkb:KRT18(gene name)|psi-mi:KRT18(display_short)|uniprotkb:CYK18(gene name synonym)|uniprotkb:Keratin-18(gene name synonym)|uniprotkb:PIG46(orf name)|uniprotkb:Cytokeratin-18(gene name synonym)|uniprotkb:Cell proliferation-inducing gene 46 protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005815"(microtubule organizing center)|go:"GO:0005829"(cytosol)|go:"GO:0005882"(intermediate filament)|go:"GO:0005912"(adherens junction)|go:"GO:0007049"(cell cycle)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009750"(response to fructose)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034451"(centriolar satellite)|go:"GO:0043000"(Golgi to plasma membrane CFTR protein transport)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045095"(keratin filament)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070365"(hepatocyte differentiation)|go:"GO:0072497"(mesenchymal stem cell differentiation)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097191"(extrinsic apoptotic signaling pathway)|go:"GO:0097284"(hepatocyte apoptotic process)|go:"GO:0098641"(cadherin binding involved in cell-cell adhesion)|go:"GO:1902488"(cholangiocyte apoptotic process)|interpro:IPR002957(Keratin, type I)|interpro:IPR018039|interpro:IPR027695|interpro:IPR039008|mint:P05783|reactome:R-HSA-6805567|reactome:R-HSA-6809371|ensembl:ENSG00000111057(gene)|ensembl:ENST00000388835(transcript)|ensembl:ENST00000388837(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|refseq:NP_000215.1|refseq:NP_954657.1|dip:DIP-633N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:6rtLZxuG0CSGcsCHEmkRKFVDeyo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q12959 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-357481|ensembl:ENSP00000391732|ensembl:ENSP00000407531|ensembl:ENSP00000499437|uniprotkb:Q12958|uniprotkb:A5YKK7|uniprotkb:B7ZMM0|uniprotkb:B9EIQ5|uniprotkb:D3DXB8|uniprotkb:D3DXB9|uniprotkb:B4DGU1|uniprotkb:B4DGZ8|uniprotkb:E7EWL7|uniprotkb:E9PG21 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:dlg1_human(display_long)|uniprotkb:DLG1(gene name)|psi-mi:DLG1(display_short)|uniprotkb:Synapse-associated protein 97(gene name synonym)|uniprotkb:hDlg(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N reactome:R-HSA-9617324|reactome:R-HSA-9620244|ensembl:ENST00000419354(transcript)|ensembl:ENST00000448528(transcript)|ensembl:ENST00000670935(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001771"(immunological synapse formation)|go:"GO:0001772"(immunological synapse)|go:"GO:0001935"(endothelial cell proliferation)|go:"GO:0002088"(lens development in camera-type eye)|ensembl:ENSG00000075711(gene)|go:"GO:0004385"(guanylate kinase activity)|go:"GO:0004721"(phosphoprotein phosphatase activity)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007015"(actin filament organization)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0043113"(receptor clustering)|go:"GO:0043219"(lateral loop)|go:"GO:0043268"(positive regulation of potassium ion transport)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048608"(reproductive structure development)|go:"GO:0048704"(embryonic skeletal system morphogenesis)|go:"GO:0043622"(cortical microtubule organization)|go:"GO:0048745"(smooth muscle tissue development)|go:"GO:0050680"(negative regulation of epithelial cell proliferation)|go:"GO:0051660"(establishment of centrosome localization)|go:"GO:0051898"(negative regulation of protein kinase B signaling)|go:"GO:0060022"(hard palate development)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0070830"(bicellular tight junction assembly)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0097016"(L27 domain binding)|go:"GO:0097025"(MPP7-DLG1-LIN7 complex)|go:"GO:0097060"(synaptic membrane)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098839"(postsynaptic density membrane)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0098919"(structural constituent of postsynaptic density)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099645"(neurotransmitter receptor localization to postsynaptic specialization membrane)|go:"GO:1902305"(regulation of sodium ion transmembrane transport)|go:"GO:1902473"(regulation of protein localization to synapse)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903286"(regulation of potassium ion import)|go:"GO:1903753"(negative regulation of p38MAPK cascade)|go:"GO:1903760"(regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization)|go:"GO:1903764"(regulation of potassium ion export across plasma membrane)|go:"GO:2000134"(negative regulation of G1/S transition of mitotic cell cycle)|interpro:IPR001452(Src homology-3)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045121"(membrane raft)|refseq:NP_001091894.1|refseq:NP_001191315.1|refseq:NP_001191316.1|refseq:NP_001191317.1|refseq:NP_004078.2|go:"GO:0008092"(cytoskeletal protein binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019902"(phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030432"(peristalsis)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030866"(cortical actin cytoskeleton organization)|go:"GO:0030953"(astral microtubule organization)|go:"GO:0031253"(cell projection membrane)|go:"GO:0031434"(mitogen-activated protein kinase kinase binding)|go:"GO:0031579"(membrane raft organization)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0031641"(regulation of myelination)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0032147"(activation of protein kinase activity)|go:"GO:0033268"(node of Ranvier)|go:"GO:0034629"|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0042110"(T cell activation)|go:"GO:0042130"(negative regulation of T cell proliferation)|go:"GO:0042383"(sarcolemma)|go:"GO:0042391"(regulation of membrane potential)|go:"GO:0042982"(amyloid precursor protein metabolic process)|go:"GO:0043005"(neuron projection)|interpro:IPR019583|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR019590|interpro:IPR020590|interpro:IPR027417|interpro:IPR036028|interpro:IPR036034|interpro:IPR036892|mint:Q12959|rcsb pdb:1PDR|rcsb pdb:2M3M|rcsb pdb:2OQS|rcsb pdb:2X7Z|rcsb pdb:3LRA|rcsb pdb:3RL7|rcsb pdb:3RL8|rcsb pdb:3W9Y|rcsb pdb:4AMH|rcsb pdb:4G69|reactome:R-HSA-399719|interpro:IPR004172(L27)|interpro:IPR008144(Guanylate kinase)|reactome:R-HSA-438066|interpro:IPR008145(Guanylate kinase/L-type calcium channel region)|interpro:IPR015143(L27-1)|interpro:IPR016313("Membrane-associated guanylate kinase (MAGUK) scaffold protein")|reactome:R-HSA-442982|reactome:R-HSA-447038|reactome:R-HSA-451308|reactome:R-HSA-5673001|reactome:R-HSA-8849932|reactome:R-HSA-9609736|refseq:XP_011510804.1|refseq:XP_011510807.1|refseq:XP_011510808.1|refseq:XP_005269346.1|refseq:NP_001277912.1|refseq:XP_016861289.1|refseq:XP_016861290.1|refseq:XP_016861291.1|refseq:XP_016861292.1|refseq:XP_016861294.1|refseq:XP_016861295.1|refseq:XP_016861296.1|refseq:XP_016861297.1|refseq:XP_016861298.1|refseq:XP_016861305.1|refseq:XP_016861306.1|refseq:XP_016861307.1|refseq:XP_016861308.1|refseq:XP_016861309.1|dip:DIP-33957N|refseq:XP_011510805.1|refseq:XP_016861299.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ax5sUROdL8kF59RhocRWG6tUUkc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P00533 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-297353|uniprotkb:Q9BZS2|uniprotkb:Q9GZX1|uniprotkb:Q9H2C9|uniprotkb:Q9H3C9|uniprotkb:Q9UMD7|uniprotkb:Q9UMD8|uniprotkb:Q9UMG5|uniprotkb:O00688|uniprotkb:O00732|uniprotkb:P06268|uniprotkb:Q14225|uniprotkb:Q92795|intact:EBI-28985169|ensembl:ENSP00000275493|uniprotkb:Q68GS5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:egfr_human(display_long)|uniprotkb:ERBB1(gene name synonym)|uniprotkb:EGFR(gene name)|psi-mi:EGFR(display_short)|uniprotkb:Receptor tyrosine-protein kinase erbB-1(gene name synonym)|uniprotkb:Proto-oncogene c-ErbB-1(gene name synonym)|uniprotkb:ERBB(gene name synonym)|uniprotkb:HER1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000146648(gene)|ensembl:ENST00000275493(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0001503"(ossification)|go:"GO:0001618"(virus receptor activity)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0001942"(hair follicle development)|go:"GO:0003682"(chromatin binding)|go:"GO:0003690"(double-stranded DNA binding)|go:"GO:0004709"(MAP kinase kinase kinase activity)|go:"GO:0004713"(protein tyrosine kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004888"(transmembrane signaling receptor activity)|go:"GO:0005006"(epidermal growth factor-activated receptor activity)|go:"GO:0005178"(integrin binding)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005886"(plasma membrane)|go:"GO:0005887"(integral component of plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0006970"(response to osmotic stress)|go:"GO:0007165"(signal transduction)|go:"GO:0007166"(cell surface receptor signaling pathway)|go:"GO:0007169"(transmembrane receptor protein tyrosine kinase signaling pathway)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007202"(activation of phospholipase C activity)|go:"GO:0007494"(midgut development)|go:"GO:0033674"(positive regulation of kinase activity)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035690"|go:"GO:0007611"(learning or memory)|go:"GO:0038083"(peptidyl-tyrosine autophosphorylation)|go:"GO:0042059"(negative regulation of epidermal growth factor receptor signaling pathway)|go:"GO:0042060"(wound healing)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033138"(positive regulation of peptidyl-serine phosphorylation)|go:"GO:0033590"(response to cobalamin)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042311"(vasodilation)|go:"GO:0033594"(response to hydroxyisoflavone)|go:"GO:0042327"(positive regulation of phosphorylation)|go:"GO:0042698"(ovulation cycle)|go:"GO:0042743"(hydrogen peroxide metabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0043006"(activation of phospholipase A2 activity by calcium-mediated signaling)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043235"(receptor complex)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043586"(tongue development)|go:"GO:0045121"(membrane raft)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0009986"(cell surface)|go:"GO:0010008"(endosome membrane)|go:"GO:0010750"(positive regulation of nitric oxide mediated signal transduction)|go:"GO:0010960"(magnesium ion homeostasis)|go:"GO:0014066"(regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016020"(membrane)|go:"GO:0007623"(circadian rhythm)|go:"GO:0016101"(diterpenoid metabolic process)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0018108"(peptidyl-tyrosine phosphorylation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030054"(cell junction)|go:"GO:0030154"(cell differentiation)|go:"GO:0030307"(positive regulation of cell growth)|go:"GO:0030324"(lung development)|go:"GO:0030335"(positive regulation of cell migration)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0031901"(early endosome membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032930"(positive regulation of superoxide anion generation)|rcsb pdb:4WD5|rcsb pdb:4WKQ|rcsb pdb:4WRG|rcsb pdb:4ZAU|rcsb pdb:4ZJV|rcsb pdb:4ZSE|rcsb pdb:5C8K|rcsb pdb:5C8M|rcsb pdb:5C8N|rcsb pdb:5CAL|rcsb pdb:5CAN|rcsb pdb:5CAO|rcsb pdb:5CAP|rcsb pdb:5CAQ|rcsb pdb:4UV7|rcsb pdb:5CAS|rcsb pdb:5CAU|rcsb pdb:5CAV|rcsb pdb:5CNN|rcsb pdb:5CNO|rcsb pdb:5CZH|rcsb pdb:5CZI|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0045740"(positive regulation of DNA replication)|go:"GO:0045780"(positive regulation of bone resorption)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045907"(positive regulation of vasoconstriction)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046328"(regulation of JNK cascade)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048143"(astrocyte activation)|go:"GO:0048408"(epidermal growth factor binding)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048661"(positive regulation of smooth muscle cell proliferation)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0050679"(positive regulation of epithelial cell proliferation)|go:"GO:0050729"(positive regulation of inflammatory response)|go:"GO:0050730"(regulation of peptidyl-tyrosine phosphorylation)|go:"GO:0050999"(regulation of nitric-oxide synthase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051117"(ATPase binding)|go:"GO:0051205"(protein insertion into membrane)|go:"GO:0051592"(response to calcium ion)|go:"GO:0051897"(positive regulation of protein kinase B signaling)|go:"GO:0051968"(positive regulation of synaptic transmission, glutamatergic)|go:"GO:0045737"(positive regulation of cyclin-dependent protein serine/threonine kinase activity)|rcsb pdb:5UGB|rcsb pdb:5UGC|rcsb pdb:5UWD|rcsb pdb:5WB7|rcsb pdb:5WB8|rcsb pdb:5X26|rcsb pdb:5X27|rcsb pdb:5X28|rcsb pdb:5X2A|rcsb pdb:5X2C|rcsb pdb:5X2F|rcsb pdb:5X2K|rcsb pdb:5XDK|rcsb pdb:5XDL|rcsb pdb:5XGM|rcsb pdb:5XGN|rcsb pdb:5XWD|rcsb pdb:5Y25|rcsb pdb:5Y9T|rcsb pdb:5YU9|rcsb pdb:5ZTO|rcsb pdb:5ZWJ|rcsb pdb:6ARU|rcsb pdb:6B3S|rcsb pdb:5D41|rcsb pdb:6D8E|rcsb pdb:6DUK|rcsb pdb:6JRJ|rcsb pdb:6JRK|rcsb pdb:6JRX|rcsb pdb:6JWL|rcsb pdb:6JX0|rcsb pdb:6JX4|rcsb pdb:6JXT|rcsb pdb:6JZ0|go:"GO:0097489"(multivesicular body, internal vesicle lumen)|go:"GO:0097708"(intracellular vesicle)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900020"(positive regulation of protein kinase C activity)|go:"GO:1900087"(positive regulation of G1/S transition of mitotic cell cycle)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1902722"(positive regulation of prolactin secretion)|go:"GO:1903078"(positive regulation of protein localization to plasma membrane)|go:"GO:1903800"(positive regulation of production of miRNAs involved in gene silencing by miRNA)|go:"GO:1905208"(negative regulation of cardiocyte differentiation)|interpro:IPR000494(EGF receptor, L domain)|interpro:IPR000719(Protein kinase, core)|interpro:IPR001245(Tyrosine protein kinase)|interpro:IPR006211(Furin-like cysteine rich region)|interpro:IPR006212(Furin-like repeat)|interpro:IPR008266(Tyrosine protein kinase, active site)|interpro:IPR009030(Growth factor, receptor)|go:"GO:0060252"(positive regulation of glial cell proliferation)|go:"GO:0070141"(response to UV-A)|go:"GO:0070257"(positive regulation of mucus secretion)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0070435"(Shc-EGFR complex)|go:"GO:0071260"(cellular response to mechanical stimulus)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0071392"(cellular response to estradiol stimulus)|go:"GO:0071549"(cellular response to dexamethasone stimulus)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0097421"(liver regeneration)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016245(Tyrosine protein kinase, receptor-type, EGF/ERB/XmrK)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR020635|interpro:IPR032778|interpro:IPR036941|mint:P00533|rcsb pdb:1DNQ|rcsb pdb:1DNR|rcsb pdb:1IVO|rcsb pdb:1M14|rcsb pdb:1M17|rcsb pdb:1MOX|rcsb pdb:1NQL|rcsb pdb:1XKK|rcsb pdb:1YY9|rcsb pdb:1Z9I|rcsb pdb:2EB2|rcsb pdb:2EB3|rcsb pdb:2EXP|rcsb pdb:2EXQ|rcsb pdb:2GS2|rcsb pdb:2GS6|rcsb pdb:2J5E|rcsb pdb:2J5F|rcsb pdb:2GS7|rcsb pdb:2J6M|rcsb pdb:2JIT|rcsb pdb:2ITN|rcsb pdb:2JIU|rcsb pdb:2ITO|rcsb pdb:2JIV|rcsb pdb:2KS1|rcsb pdb:2ITP|rcsb pdb:2M0B|rcsb pdb:2M20|rcsb pdb:2ITQ|rcsb pdb:2N5S|rcsb pdb:2RF9|rcsb pdb:2RFD|rcsb pdb:2RFE|rcsb pdb:2RGP|rcsb pdb:3B2U|rcsb pdb:3B2V|rcsb pdb:3BEL|rcsb pdb:2ITT|rcsb pdb:3BUO|rcsb pdb:3C09|rcsb pdb:3G5V|rcsb pdb:3G5Y|rcsb pdb:3GOP|rcsb pdb:3GT8|rcsb pdb:3IKA|rcsb pdb:3LZB|rcsb pdb:2ITU|rcsb pdb:3NJP|rcsb pdb:3OB2|rcsb pdb:2ITV|rcsb pdb:3OP0|rcsb pdb:2ITW|rcsb pdb:2ITX|rcsb pdb:2ITY|rcsb pdb:3P0Y|rcsb pdb:2ITZ|rcsb pdb:3PFV|rcsb pdb:3POZ|rcsb pdb:3QWQ|rcsb pdb:3UG1|rcsb pdb:3UG2|rcsb pdb:3VJN|rcsb pdb:3VJO|rcsb pdb:3VRP|rcsb pdb:3VRR|rcsb pdb:5EM7|rcsb pdb:5EM8|rcsb pdb:5FED|rcsb pdb:5FEE|rcsb pdb:5FEQ|rcsb pdb:5GMP|rcsb pdb:5GNK|rcsb pdb:5GTY|rcsb pdb:5GTZ|rcsb pdb:5HCX|rcsb pdb:5HCY|rcsb pdb:5HCZ|rcsb pdb:5HG5|rcsb pdb:5HG7|rcsb pdb:5HG8|rcsb pdb:5HG9|rcsb pdb:5HIB|rcsb pdb:5HIC|rcsb pdb:5EDP|rcsb pdb:5J9Y|rcsb pdb:5J9Z|rcsb pdb:5JEB|rcsb pdb:5LV6|rcsb pdb:5SX4|rcsb pdb:5EDQ|rcsb pdb:5EDR|rcsb pdb:5EM5|rcsb pdb:5SX5|rcsb pdb:5U8L|rcsb pdb:5UG8|rcsb pdb:5EM6|rcsb pdb:5UG9|rcsb pdb:5UGA|rcsb pdb:3W2O|rcsb pdb:4JR3|rcsb pdb:3W2P|rcsb pdb:3W2Q|rcsb pdb:4JRV|rcsb pdb:4KRL|rcsb pdb:4KRM|rcsb pdb:4KRO|rcsb pdb:3W2R|rcsb pdb:4KRP|rcsb pdb:4LI5|rcsb pdb:4LL0|rcsb pdb:3W2S|rcsb pdb:4LQM|rcsb pdb:4LRM|rcsb pdb:3W32|rcsb pdb:4R3P|rcsb pdb:4R3R|rcsb pdb:4R5S|rcsb pdb:3W33|rcsb pdb:4RIW|rcsb pdb:4G5J|rcsb pdb:4RIX|rcsb pdb:4G5P|rcsb pdb:4RIY|rcsb pdb:4RJ4|rcsb pdb:4RJ5|rcsb pdb:4HJO|rcsb pdb:4I1Z|rcsb pdb:4I20|rcsb pdb:4I21|rcsb pdb:4I22|rcsb pdb:4I23|rcsb pdb:4I24|rcsb pdb:4JQ7|rcsb pdb:4JQ8|rcsb pdb:4RJ6|rcsb pdb:4RJ7|rcsb pdb:4RJ8|rcsb pdb:4TKS|rcsb pdb:4UIP|rcsb pdb:6LUD|rcsb pdb:6P1D|rcsb pdb:6P1L|rcsb pdb:6P8Q|rcsb pdb:6S89|rcsb pdb:6S8A|rcsb pdb:6S9B|rcsb pdb:6S9C|rcsb pdb:6S9D|rcsb pdb:6TFU|rcsb pdb:6LUB|rcsb pdb:6TFV|rcsb pdb:6TFW|rcsb pdb:6TFY|rcsb pdb:6TFZ|rcsb pdb:6TG0|rcsb pdb:6TG1|rcsb pdb:6V5N|rcsb pdb:6V5P|rcsb pdb:6V66|rcsb pdb:6V6K|rcsb pdb:6V6O|rcsb pdb:6VH4|rcsb pdb:6VHN|rcsb pdb:6VHP|rcsb pdb:6WA2|rcsb pdb:6WAK|rcsb pdb:6WXN|rcsb pdb:6XL4|rcsb pdb:6Z4B|rcsb pdb:6Z4D|rcsb pdb:7A2A|rcsb pdb:7AEI|rcsb pdb:7AEM|reactome:R-HSA-1227986|reactome:R-HSA-1236382|reactome:R-HSA-1236394|reactome:R-HSA-1250196|reactome:R-HSA-1251932|reactome:R-HSA-1257604|reactome:R-HSA-177929|reactome:R-HSA-180292|reactome:R-HSA-180336|reactome:R-HSA-182971|reactome:R-HSA-1963640|reactome:R-HSA-1963642|reactome:R-HSA-212718|reactome:R-HSA-2179392|reactome:R-HSA-2219530|reactome:R-HSA-445144|reactome:R-HSA-5637810|reactome:R-HSA-5638303|reactome:R-HSA-5673001|reactome:R-HSA-6785631|reactome:R-HSA-6811558|reactome:R-HSA-8847993|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-179812|reactome:R-HSA-8857538|reactome:R-HSA-8863795|reactome:R-HSA-9009391|reactome:R-HSA-9013507|reactome:R-HSA-9609690|reactome:R-HSA-9634638|reactome:R-HSA-9664565|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-8866910|refseq:NP_005219.2|refseq:NP_958439.1|refseq:NP_958440.1|refseq:NP_958441.1|ensembl:ENSP00000275493|ensembl:ENST00000342916|ensembl:ENSP00000342376|ensembl:ENST00000344576|ensembl:ENSP00000345973|ensembl:ENST00000420316|ensembl:ENSP00000413843|dip:DIP-405N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:gXB5slVTC+z8DdqqXIzXG7lDwk09606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14247 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-351886|intact:EBI-3959948|ensembl:ENSP00000301843|ensembl:ENSP00000500756|uniprotkb:Q8N707|uniprotkb:Q96H99 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:src8_human(display_long)|uniprotkb:CTTN(gene name)|psi-mi:CTTN(display_short)|uniprotkb:EMS1(gene name synonym)|uniprotkb:Amplaxin(gene name synonym)|uniprotkb:Oncogene EMS1(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005222.2|go:"GO:0006886"(intracellular protein transport)|go:"GO:0006898"(receptor-mediated endocytosis)|go:"GO:0006930"(substrate-dependent cell migration, cell extension)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0030027"(lamellipodium)|go:"GO:0030041"(actin filament polymerization)|go:"GO:0030427"(site of polarized growth)|go:"GO:0030516"(regulation of axon extension)|go:"GO:0030833"(regulation of actin filament polymerization)|go:"GO:0030838"(positive regulation of actin filament polymerization)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0043197"(dendritic spine)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045296"(cadherin binding)|go:"GO:0045987"(positive regulation of smooth muscle contraction)|go:"GO:0048041"(focal adhesion assembly)|go:"GO:0048812"(neuron projection morphogenesis)|go:"GO:0048870"(cell motility)|go:"GO:0051015"(actin filament binding)|go:"GO:0097062"(dendritic spine maintenance)|go:"GO:0097581"(lamellipodium organization)|go:"GO:1903146"(regulation of autophagy of mitochondrion)|go:"GO:1990023"(mitotic spindle midzone)|go:"GO:2001237"(negative regulation of extrinsic apoptotic signaling pathway)|interpro:IPR001452(Src homology-3)|interpro:IPR003134(Hs1/Cortactin)|interpro:IPR015503(Cortactin)|interpro:IPR035716|interpro:IPR036028|mint:Q14247|rcsb pdb:1X69|rcsb pdb:2D1X|reactome:R-HSA-5627123|reactome:R-HSA-8856828|ensembl:ENSG00000085733(gene)|ensembl:ENSG00000288401(gene)|ensembl:ENST00000301843(transcript)|ensembl:ENST00000671805(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0002102"(podosome)|go:"GO:0005522"(profilin binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005905"(clathrin-coated pit)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|refseq:NP_001171669.1|refseq:NP_612632.1|dip:DIP-33190N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:uzhAnL5Fu9Mgg9/LWeNiaYIwNVU9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P83731 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353146|ensembl:ENSP00000377640|uniprotkb:P38663|uniprotkb:Q6IBS3|uniprotkb:B2R4Y3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl24_human(display_long)|uniprotkb:RPL24(gene name)|psi-mi:RPL24(display_short)|uniprotkb:60S ribosomal protein L30(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL24(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0016020"(membrane)|go:"GO:0021554"(optic nerve development)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0031290"(retinal ganglion cell axon guidance)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045202"(synapse)|go:"GO:0045296"(cadherin binding)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|interpro:IPR000988(Ribosomal protein L24e)|interpro:IPR011017(TRASH)|interpro:IPR023442|interpro:IPR038630|mint:P83731|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZMI|rcsb pdb:6ZME|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000114391(gene)|ensembl:ENST00000394077(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0010458"(exit from mitosis)|refseq:NP_000977.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+Ah+YGgcjqOsk5ZS1HZUMQA/Of89606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q14160 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-357345|uniprotkb:Q6P496|uniprotkb:Q7Z5D1|uniprotkb:Q8WWV8|uniprotkb:Q96C69|uniprotkb:Q96GG1|ensembl:ENSP00000322938|ensembl:ENSP00000349486|ensembl:ENSP00000366756 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:scrib_human(display_long)|uniprotkb:SCRIB(gene name)|psi-mi:SCRIB(display_short)|uniprotkb:CRIB1(gene name synonym)|uniprotkb:KIAA0147(gene name synonym)|uniprotkb:LAP4(gene name synonym)|uniprotkb:SCRB1(gene name synonym)|uniprotkb:VARTUL(gene name synonym)|uniprotkb:Protein LAP4(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_056171.3|refseq:NP_874365.3|dip:DIP-31259N|ensembl:ENSG00000180900(gene)|ensembl:ENST00000320476(transcript)|ensembl:ENST00000356994(transcript)|ensembl:ENST00000377533(transcript)|go:"GO:0001768"(establishment of T cell polarity)|go:"GO:0001772"(immunological synapse)|go:"GO:0001843"(neural tube closure)|go:"GO:0001921"(positive regulation of receptor recycling)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0008283"(cell population proliferation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016080"(synaptic vesicle targeting)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016477"(cell migration)|go:"GO:0021747"(cochlear nucleus development)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030683"(mitigation of host immune response by virus)|go:"GO:0030859"(polarized epithelial cell differentiation)|go:"GO:0032729"(positive regulation of interferon-gamma production)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035089"(establishment of apical/basal cell polarity)|go:"GO:0035748"(myelin sheath abaxonal region)|go:"GO:0036342"(post-anal tail morphogenesis)|go:"GO:0039563"(suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity)|go:"GO:0039564"(suppression by virus of host JAK-STAT cascade via inhibition of STAT2 activity)|go:"GO:0042060"(wound healing)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043615"(astrocyte cell migration)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0045296"(cadherin binding)|go:"GO:0045930"(negative regulation of mitotic cell cycle)|go:"GO:0046007"(negative regulation of activated T cell proliferation)|go:"GO:0048488"(synaptic vesicle endocytosis)|go:"GO:0050918"(positive chemotaxis)|go:"GO:0060088"(auditory receptor cell stereocilium organization)|go:"GO:0060561"(apoptotic process involved in morphogenesis)|go:"GO:0060603"(mammary gland duct morphogenesis)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071896"(protein localization to adherens junction)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0097120"(receptor localization to synapse)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098793"(presynapse)|go:"GO:0098887"(neurotransmitter receptor transport, endosome to postsynaptic membrane)|go:"GO:0098968"(neurotransmitter receptor transport postsynaptic membrane to endosome)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099147"(extrinsic component of postsynaptic density membrane)|go:"GO:0099149"(regulation of postsynaptic neurotransmitter receptor internalization)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR036034|mint:Q14160|rcsb pdb:1UJU|rcsb pdb:1WHA|rcsb pdb:1X5Q|rcsb pdb:2W4F|rcsb pdb:4WYT|rcsb pdb:4WYU|rcsb pdb:5VWC|rcsb pdb:5VWI|rcsb pdb:5VWK|rcsb pdb:6EEY|rcsb pdb:6ESP|rcsb pdb:6MS1|rcsb pdb:6MTU|rcsb pdb:6MTV|rcsb pdb:6MYE|rcsb pdb:6MYF|rcsb pdb:6XA6|rcsb pdb:6XA7|rcsb pdb:6XA8|rcsb pdb:7JO7|reactome:R-HSA-4608870|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013409|reactome:R-HSA-9696264|reactome:R-HSA-9696270 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:y4lIQ2NivmndHYd/JXSKvU2jv+w9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96RT1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-993903|uniprotkb:Q86W38|uniprotkb:Q9NR18|uniprotkb:Q9NW48|uniprotkb:Q9ULJ5|ensembl:ENSP00000284037|uniprotkb:A0AVR1|uniprotkb:B4E3F1|uniprotkb:B7ZLV9|uniprotkb:E9PCR8|uniprotkb:Q1RMD0|uniprotkb:E7EQW9 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:erbin_human(display_long)|uniprotkb:ERBIN(gene name)|psi-mi:ERBIN(display_short)|uniprotkb:Densin-180-like protein(gene name synonym)|uniprotkb:ERBB2IP(gene name synonym)|uniprotkb:Erbb2-interacting protein(gene name synonym)|uniprotkb:KIAA1225(gene name synonym)|uniprotkb:LAP2(gene name synonym)|uniprotkb:Protein LAP2(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001240628.1|refseq:NP_001240630.1|ensembl:ENSG00000112851(gene)|ensembl:ENST00000284037(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005176"(ErbB-2 class receptor binding)|go:"GO:0005200"(structural constituent of cytoskeleton)|go:"GO:0005604"(basement membrane)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005886"(plasma membrane)|go:"GO:0006605"(protein targeting)|go:"GO:0007155"(cell adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0009925"(basal plasma membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0030054"(cell junction)|go:"GO:0030056"(hemidesmosome)|go:"GO:0031965"(nuclear membrane)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032495"(response to muramyl dipeptide)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0045104"(intermediate filament cytoskeleton organization)|go:"GO:0045175"(basal protein localization)|go:"GO:0045197"(establishment or maintenance of epithelial cell apical/basal polarity)|go:"GO:0046579"(positive regulation of Ras protein signal transduction)|go:"GO:0070433"(negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071638"(negative regulation of monocyte chemotactic protein-1 production)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR001611(Leucine-rich repeat)|interpro:IPR003591(Leucine-rich repeat, typical subtype)|interpro:IPR032675|interpro:IPR032927|interpro:IPR036034|rcsb pdb:1MFG|rcsb pdb:1MFL|rcsb pdb:1N7T|rcsb pdb:2H3L|rcsb pdb:2QBW|rcsb pdb:3CH8|rcsb pdb:6Q0M|rcsb pdb:6Q0N|rcsb pdb:6Q0U|rcsb pdb:6UBG|rcsb pdb:6UBH|reactome:R-HSA-1227986|reactome:R-HSA-8863795|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013408|reactome:R-HSA-9013106|reactome:R-HSA-9013423|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9634285|reactome:R-HSA-9652282|reactome:R-HSA-9664565|reactome:R-HSA-9665233|reactome:R-HSA-9665244|reactome:R-HSA-9665245|reactome:R-HSA-9665246|reactome:R-HSA-9665247|reactome:R-HSA-9665249|reactome:R-HSA-9665250|reactome:R-HSA-9665251|reactome:R-HSA-9665348|reactome:R-HSA-9665686|reactome:R-HSA-9665737|refseq:NP_001006600.1|refseq:NP_061165.1|refseq:NP_001240626.1|refseq:NP_001240627.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:kITHWAgafb7t7RFgzs5ff7XCL3Y9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q5T5P2 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-746898|uniprotkb:A5LHW9|uniprotkb:A6PVQ5|uniprotkb:A6PVQ6|uniprotkb:A6PVQ7|uniprotkb:Q5T5P3|uniprotkb:Q4KMG4|uniprotkb:Q5T7H3|uniprotkb:Q6MZZ6|uniprotkb:Q6ZUI4|uniprotkb:Q8WV45|uniprotkb:Q9NSR2|uniprotkb:Q9ULK3|ensembl:ENSP00000365637|uniprotkb:A6NLF3|uniprotkb:B9EGK4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:skt_human(display_long)|uniprotkb:KIAA1217(gene name)|psi-mi:KIAA1217(display_short)|uniprotkb:SKT(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001091970.1|refseq:NP_001269696.1|refseq:NP_001269697.1|refseq:NP_001269698.1|refseq:NP_001269699.1|refseq:NP_062536.2|refseq:XP_016871918.1|ensembl:ENSG00000120549(gene)|ensembl:ENST00000376454(transcript)|go:"GO:0005737"(cytoplasm)|go:"GO:0030234"(enzyme regulator activity)|go:"GO:0048706"(embryonic skeletal system development)|interpro:IPR022782|interpro:IPR026725|refseq:XP_005252573.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:3rlNZUWLC4c0hvktiGEo55Sj15Q9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P46109 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-910|uniprotkb:A8KA44|intact:EBI-3451075|uniprotkb:D3DX35|ensembl:ENSP00000346300|ensembl:ENSP00000396646 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:crkl_human(display_long)|uniprotkb:CRKL(gene name)|psi-mi:CRKL(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_005198.1|dip:DIP-29165N|ensembl:ENSG00000099942(gene)|ensembl:ENST00000354336(transcript)|ensembl:ENST00000411769(transcript)|go:"GO:0001558"(regulation of cell growth)|go:"GO:0001568"(blood vessel development)|go:"GO:0001655"(urogenital system development)|go:"GO:0001764"(neuron migration)|go:"GO:0001783"(B cell apoptotic process)|go:"GO:0001784"(phosphotyrosine residue binding)|go:"GO:0001933"(negative regulation of protein phosphorylation)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0003151"(outflow tract morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006629"(lipid metabolic process)|go:"GO:0007254"(JNK cascade)|go:"GO:0007265"(Ras protein signal transduction)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007338"(single fertilization)|go:"GO:0007416"(synapse assembly)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008543"(fibroblast growth factor receptor signaling pathway)|go:"GO:0008584"(male gonad development)|go:"GO:0009952"(anterior/posterior pattern specification)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0016358"(dendrite development)|go:"GO:0021766"(hippocampus development)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030010"(establishment of cell polarity)|go:"GO:0031594"(neuromuscular junction)|go:"GO:0032991"(protein-containing complex)|go:"GO:0033628"(regulation of cell adhesion mediated by integrin)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035685"(helper T cell diapedesis)|go:"GO:0035690"|go:"GO:0038026"(reelin-mediated signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0048384"(retinoic acid receptor signaling pathway)|go:"GO:0048538"(thymus development)|go:"GO:0050773"(regulation of dendrite development)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0060017"(parathyroid gland development)|go:"GO:0060326"(cell chemotaxis)|go:"GO:0060465"(pharynx development)|go:"GO:0070374"(positive regulation of ERK1 and ERK2 cascade)|go:"GO:0071560"(cellular response to transforming growth factor beta stimulus)|go:"GO:0086100"(endothelin receptor signaling pathway)|go:"GO:0090630"(activation of GTPase activity)|go:"GO:0095500"(acetylcholine receptor signaling pathway)|go:"GO:0098749"(cerebellar neuron development)|go:"GO:0098761"(cellular response to interleukin-7)|go:"GO:0098890"(extrinsic component of postsynaptic membrane)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1903977"(positive regulation of glial cell migration)|go:"GO:1904393"(regulation of skeletal muscle acetylcholine-gated channel clustering)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:2000404"(regulation of T cell migration)|interpro:IPR000980(SH2 motif)|interpro:IPR001452(Src homology-3)|interpro:IPR035457|interpro:IPR035458|interpro:IPR036028|interpro:IPR036860|mint:P46109|rcsb pdb:2BZX|rcsb pdb:2BZY|rcsb pdb:2DBK|rcsb pdb:2EO3|rcsb pdb:2LQN|rcsb pdb:2LQW|reactome:R-HSA-170968|reactome:R-HSA-186763|reactome:R-HSA-8875555|reactome:R-HSA-8875656|reactome:R-HSA-9027284|reactome:R-HSA-912631 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:1YwlbUPPuijisz7AJM4Qkp7yJBI9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q96TA1 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2514593|uniprotkb:Q4LE55|uniprotkb:Q5VVW7|intact:EBI-28984656|ensembl:ENSP00000362409|uniprotkb:Q9NT35|uniprotkb:Q9BUS2|uniprotkb:Q5VVW6 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:niba2_human(display_long)|uniprotkb:NIBAN2(gene name)|psi-mi:NIBAN2(display_short)|uniprotkb:C9orf88(gene name synonym)|uniprotkb:FAM129B(gene name synonym)|uniprotkb:Meg-3(gene name synonym)|uniprotkb:Melanoma invasion by ERK(gene name synonym)|uniprotkb:Niban-like protein 1(gene name synonym)|uniprotkb:Protein FAM129B(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:2000679"(positive regulation of transcription regulatory region DNA binding)|interpro:IPR001849(Pleckstrin-like)|interpro:IPR011993(Pleckstrin homology-type)|interpro:IPR026088|mint:Q96TA1|rcsb pdb:7CTP|ensembl:ENSG00000136830(gene)|ensembl:ENST00000373312(transcript)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007411"(axon guidance)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0030154"(cell differentiation)|go:"GO:0030948"(negative regulation of vascular endothelial growth factor receptor signaling pathway)|go:"GO:0032274"(gonadotropin secretion)|go:"GO:0040019"(positive regulation of embryonic development)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044029"(hypomethylation of CpG island)|go:"GO:0045296"(cadherin binding)|go:"GO:0045746"(negative regulation of Notch signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048743"(positive regulation of skeletal muscle fiber development)|go:"GO:0070062"(extracellular exosome)|go:"GO:2000279"(negative regulation of DNA biosynthetic process)|refseq:NP_001030611.1|refseq:NP_073744.2|ensembl:ENSP00000362409|ensembl:ENST00000373314|ensembl:ENSP00000362411 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:xdcw2BLz6uu0zyGi/NzvzPLrKUk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q969Q0 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2877705|ensembl:ENSP00000346012|uniprotkb:Q3B7A5 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl36l_human(display_long)|uniprotkb:RPL36AL(gene name)|psi-mi:RPL36AL(display_short)|uniprotkb:Large ribosomal subunit protein eL42-like(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000165502(gene)|ensembl:ENST00000298289(transcript)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006412"(translation)|go:"GO:0022625"(cytosolic large ribosomal subunit)|interpro:IPR000552(Ribosomal protein L44e)|interpro:IPR011332(Ribosomal protein, zinc-binding)|mint:Q969Q0|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-9633012|refseq:NP_000992.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:+jT5oFy79StEavkvHz6j/36g/qg9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P12830 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-727477|uniprotkb:Q13799|uniprotkb:Q14216|uniprotkb:Q15855|uniprotkb:Q16194|uniprotkb:Q4PJ14|uniprotkb:A8K1U7|intact:EBI-28986920|ensembl:ENSP00000261769|uniprotkb:Q9UII8 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:cadh1_human(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CAM 120/80(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short)|uniprotkb:CDHE(gene name synonym)|uniprotkb:UVO(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|ensembl:ENSG00000039068(gene)|refseq:NP_004351.1|ensembl:ENST00000261769(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|refseq:NP_001304113.1|refseq:NP_001304114.1|refseq:NP_001304115.1|ensembl:ENSP00000261769|ensembl:ENST00000422392|ensembl:ENSP00000414946|go:"GO:0016600"(flotillin complex)|go:"GO:0021983"(pituitary gland development)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0031175"(neuron projection development)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042493"|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099576"(regulation of protein catabolic process at postsynapse, modulating synaptic transmission)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|mint:P12830|rcsb pdb:1O6S|rcsb pdb:2O72|rcsb pdb:2OMT|rcsb pdb:2OMU|rcsb pdb:2OMV|rcsb pdb:2OMX|rcsb pdb:2OMY|rcsb pdb:2OMZ|rcsb pdb:3FF7|rcsb pdb:3FF8|rcsb pdb:3L6X|rcsb pdb:3L6Y|rcsb pdb:6VEL|reactome:R-HSA-1474228|reactome:R-HSA-198933|reactome:R-HSA-216083|reactome:R-HSA-351906|reactome:R-HSA-418990|reactome:R-HSA-5626467|reactome:R-HSA-8876493|rcsb pdb:4ZT1|rcsb pdb:4ZTE|rcsb pdb:6CXY|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|dip:DIP-477N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WI/yBLas6W5mlgbyOErqeeUFNA49606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35222 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P21333 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-350432|uniprotkb:Q8NF52|intact:EBI-1103234|ensembl:ENSP00000358866|uniprotkb:Q5HY53|uniprotkb:Q5HY55|uniprotkb:E9KL45 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:flna_human(display_long)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0007195"(adenylate cyclase-inhibiting dopamine receptor signaling pathway)|go:"GO:1902396"(protein localization to bicellular tight junction)|refseq:NP_001104026.1|refseq:NP_001447.2|ensembl:ENSG00000196924(gene)|ensembl:ENST00000369850(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001664"(G protein-coupled receptor binding)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001974"(blood vessel remodeling)|go:"GO:0003007"(heart morphogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048680"(positive regulation of axon regeneration)|go:"GO:0050808"(synapse organization)|go:"GO:0050821"(protein stabilization)|go:"GO:0051015"(actin filament binding)|go:"GO:0051020"(GTPase binding)|go:"GO:0051220"(cytoplasmic sequestering of protein)|go:"GO:0051764"(actin crosslink formation)|go:"GO:0060271"(cilium assembly)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071526"(semaphorin-plexin signaling pathway)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0090042"(tubulin deacetylation)|go:"GO:0090307"(mitotic spindle assembly)|go:"GO:0097368"(establishment of Sertoli cell barrier)|go:"GO:0097440"(apical dendrite)|go:"GO:0098794"(postsynapse)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1900026"(positive regulation of substrate adhesion-dependent cell spreading)|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|go:"GO:0046332"(SMAD binding)|go:"GO:0010977"(negative regulation of neuron projection development)|go:"GO:0015459"(potassium channel regulator activity)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0016479"(negative regulation of transcription by RNA polymerase I)|go:"GO:0019900"(kinase binding)|go:"GO:0008134"(transcription factor binding)|go:"GO:0021943"(formation of radial glial scaffolds)|go:"GO:0021987"(cerebral cortex development)|go:"GO:0030018"(Z disc)|go:"GO:0030334"(regulation of cell migration)|go:"GO:0030863"(cortical cytoskeleton)|go:"GO:0031267"(small GTPase binding)|go:"GO:0031523"(Myb complex)|go:"GO:0031532"(actin cytoskeleton reorganization)|go:"GO:0031852"(mu-type opioid receptor binding)|go:"GO:0032233"(positive regulation of actin filament bundle assembly)|go:"GO:0032432"(actin filament bundle)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034988"(Fc-gamma receptor I complex binding)|go:"GO:0042177"(negative regulation of protein catabolic process)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042789"(mRNA transcription by RNA polymerase II)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043113"(receptor clustering)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043198"(dendritic shaft)|go:"GO:0043204"(perikaryon)|go:"GO:0043433"(negative regulation of DNA-binding transcription factor activity)|go:"GO:0044295"(axonal growth cone)|go:"GO:0044319"(wound healing, spreading of cells)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0045022"(early endosome to late endosome transport)|go:"GO:0045184"(establishment of protein localization)|go:"GO:0045216"(cell-cell junction organization)|go:"GO:0045296"(cadherin binding)|reactome:R-HSA-114608|reactome:R-HSA-430116|reactome:R-HSA-446353|reactome:R-HSA-5627123|reactome:R-HSA-8983711|rcsb pdb:6EW1|go:"GO:1905031"(regulation of membrane repolarization during cardiac muscle cell action potential)|go:"GO:2000179"(positive regulation of neural precursor cell proliferation)|go:"GO:2001046"(positive regulation of integrin-mediated signaling pathway)|go:"GO:2001224"(positive regulation of neuron migration)|interpro:IPR001298(Filamin/ABP280 repeat)|interpro:IPR001589(Actinin-type, actin-binding, conserved site)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR014756(Immunoglobulin E-set)|interpro:IPR017868|interpro:IPR036872|interpro:IPR044801|mint:P21333|rcsb pdb:2AAV|rcsb pdb:2BP3|rcsb pdb:2BRQ|rcsb pdb:2J3S|rcsb pdb:2JF1|rcsb pdb:2K3T|rcsb pdb:2K7P|rcsb pdb:2K7Q|rcsb pdb:2MTP|rcsb pdb:2W0P|rcsb pdb:2WFN|rcsb pdb:3CNK|rcsb pdb:3HOC|rcsb pdb:3HOP|rcsb pdb:3HOR|rcsb pdb:3ISW|rcsb pdb:3RGH|rcsb pdb:4M9P|rcsb pdb:4P3W|rcsb pdb:5XR1|rcsb pdb:6D8C|go:"GO:1905000"(regulation of membrane repolarization during atrial cardiac muscle cell action potential)|dip:DIP-1136N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:ZxGK5OSMy8cNsyt7Ax2KXb8bn9M9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O60716 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-701927|uniprotkb:A8K939|uniprotkb:Q6DHZ7|uniprotkb:O15088|uniprotkb:O60713|uniprotkb:O60714|uniprotkb:O60715|uniprotkb:O60935|uniprotkb:Q6RBX8|uniprotkb:Q9UP71|uniprotkb:Q9UP72|uniprotkb:Q9UP73|ensembl:ENSP00000382004 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ctnd1_human(display_long)|uniprotkb:p120 catenin(gene name synonym)|uniprotkb:Cadherin-associated Src substrate(gene name synonym)|uniprotkb:"p120(cas)"(gene name synonym)|uniprotkb:CTNND1(gene name)|psi-mi:CTNND1(display_short)|uniprotkb:KIAA0384(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001078927.1|refseq:NP_001078928.1|refseq:NP_001078929.1|refseq:NP_001078930.1|refseq:NP_001078931.1|refseq:NP_001078932.1|refseq:NP_001078933.1|refseq:NP_001078934.1|refseq:NP_001078935.1|refseq:NP_001078936.1|refseq:NP_001078937.1|refseq:NP_001078938.1|refseq:NP_001193812.1|refseq:NP_001193813.1|refseq:NP_001193814.1|refseq:NP_001193815.1|refseq:NP_001193816.1|refseq:NP_001193817.1|refseq:NP_001193818.1|refseq:NP_001193819.1|refseq:NP_001193820.1|refseq:NP_001322.1|dip:DIP-33850N|ensembl:ENSG00000198561(gene)|ensembl:ENST00000399050(transcript)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0007043"(cell-cell junction assembly)|go:"GO:0007420"(brain development)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016342"(catenin complex)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0043197"(dendritic spine)|go:"GO:0044331"(cell-cell adhesion mediated by cadherin)|go:"GO:0045296"(cadherin binding)|go:"GO:0050821"(protein stabilization)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098686"(hippocampal mossy fiber to CA3 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:0099072"(regulation of postsynaptic membrane neurotransmitter receptor levels)|go:"GO:0099092"(postsynaptic density, intracellular component)|interpro:IPR000225(Armadillo)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR028435|interpro:IPR028439|mint:O60716|rcsb pdb:3L6X|rcsb pdb:3L6Y|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-8876493 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:HgMvbcDKedE291TIvIOqLFT3srw9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P47914 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-714039|uniprotkb:Q6IPY3|ensembl:ENSP00000418346|ensembl:ENSP00000418868|ensembl:ENSP00000420673|ensembl:ENSP00000294189|ensembl:ENSP00000417048|ensembl:ENSP00000418153|uniprotkb:B2R4M8|uniprotkb:A8K0H3 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl29_human(display_long)|uniprotkb:Cell surface heparin-binding protein HIP(gene name synonym)|uniprotkb:RPL29(gene name)|psi-mi:RPL29(display_short)|uniprotkb:Large ribosomal subunit protein eL29(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENST00000294189(transcript)|ensembl:ENST00000466397(transcript)|ensembl:ENST00000475248(transcript)|ensembl:ENST00000479017(transcript)|ensembl:ENST00000492277(transcript)|ensembl:ENST00000495383(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0007566"(embryo implantation)|go:"GO:0008201"(heparin binding)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|interpro:IPR002673(Ribosomal protein L29e)|mint:P47914|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|ensembl:ENSG00000162244(gene)|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_000983.1|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:XZUSMDDzycAi6QEXYbljXaeVg0U9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P62750 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-353254|uniprotkb:P29316|uniprotkb:Q92774|uniprotkb:P39024|uniprotkb:B2R5B2|ensembl:ENSP00000389103 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:rl23a_human(display_long)|uniprotkb:RPL23A(gene name)|psi-mi:RPL23A(display_short)|uniprotkb:Large ribosomal subunit protein uL23(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6SXO|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|refseq:NP_000975.2|ensembl:ENSG00000198242(gene)|ensembl:ENST00000422514(transcript)|go:"GO:0000027"(ribosomal large subunit assembly)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:1904841"(TORC2 complex binding)|interpro:IPR001014(Ribosomal protein L23, conserved site)|interpro:IPR005633(Ribosomal protein L23/L25, N-terminal)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR012678(Ribosomal protein L23/L15e, core)|interpro:IPR013025(Ribosomal protein L25/L23)|interpro:IPR019985|mint:P62750|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:lA1ubRFO9/Tl54Z1dKUzoCKvpAo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q09666 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2555881|ensembl:ENSP00000367263|uniprotkb:A1A586 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ahnk_human(display_long)|uniprotkb:PM227(gene name synonym)|uniprotkb:Desmoyokin(gene name synonym)|uniprotkb:AHNAK(gene name)|psi-mi:AHNAK(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001611.1|ensembl:ENSG00000124942(gene)|ensembl:ENST00000378024(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016020"(membrane)|go:"GO:0030315"(T-tubule)|go:"GO:0031982"(vesicle)|go:"GO:0042383"(sarcolemma)|go:"GO:0042802"(identical protein binding)|go:"GO:0043034"(costamere)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0044291"(cell-cell contact zone)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097493"(structural molecule activity conferring elasticity)|go:"GO:1901385"(regulation of voltage-gated calcium channel activity)|interpro:IPR001478(PDZ/DHR/GLGF)|interpro:IPR036034|mint:Q09666|rcsb pdb:4DRW|rcsb pdb:4FTG|rcsb pdb:4HRG|refseq:NP_001333374.1|refseq:NP_001333375.1|refseq:NP_076965.2 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:u1oecAyIihgxzfTz0jholE8wksA9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P14923 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:P35221 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467 - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:Q9UN36 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-3895741|uniprotkb:B4DE86|uniprotkb:B3KUE3|uniprotkb:B7WP11|uniprotkb:B7WPD5|uniprotkb:D3DS07|uniprotkb:D3DS10|uniprotkb:Q567T1|uniprotkb:Q68DW2|uniprotkb:Q86U08|uniprotkb:Q86U46|uniprotkb:Q96FD3|uniprotkb:Q96FT0|uniprotkb:Q96JU0|uniprotkb:Q96PN0|uniprotkb:Q9BQH5|uniprotkb:Q9ULH2|ensembl:ENSP00000298687|ensembl:ENSP00000380949|ensembl:ENSP00000380951|ensembl:ENSP00000380956|ensembl:ENSP00000451712 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:ndrg2_human(display_long)|uniprotkb:NDRG2(gene name)|psi-mi:NDRG2(display_short)|uniprotkb:KIAA1248(gene name synonym)|uniprotkb:SYLD(gene name synonym)|uniprotkb:Protein Syld709613(gene name synonym)|uniprotkb:N-myc downstream-regulated gene 2 protein(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N refseq:XP_011535298.1|refseq:XP_011535299.1|refseq:XP_011535300.1|refseq:XP_011535301.1|refseq:XP_011535303.1|refseq:XP_011535304.1|refseq:NP_057334.1|refseq:NP_963293.1|refseq:NP_963294.1|refseq:NP_963831.1|refseq:NP_963832.1|refseq:NP_963833.1|refseq:NP_963834.1|refseq:NP_963835.1|refseq:NP_001269140.1|refseq:NP_001269141.1|refseq:NP_001269142.1|refseq:NP_001269143.1|refseq:NP_001269144.1|refseq:NP_001269145.1|refseq:NP_001307258.1|ensembl:ENSG00000165795(gene)|ensembl:ENST00000298687(transcript)|ensembl:ENST00000397851(transcript)|ensembl:ENST00000397853(transcript)|ensembl:ENST00000397858(transcript)|ensembl:ENST00000556147(transcript)|go:"GO:0001818"(negative regulation of cytokine production)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0007165"(signal transduction)|go:"GO:0010574"(regulation of vascular endothelial growth factor production)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030154"(cell differentiation)|go:"GO:0030426"(growth cone)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048662"(negative regulation of smooth muscle cell proliferation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070373"(negative regulation of ERK1 and ERK2 cascade)|go:"GO:0090361"(regulation of platelet-derived growth factor production)|interpro:IPR004142(Ndr)|interpro:IPR029058|interpro:IPR030690|mint:Q9UN36|rcsb pdb:2XMQ|rcsb pdb:2XMR|rcsb pdb:2XMS - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:1fwzaT5UDNTvN+mYcASdfy2BMgo9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:F1PAA9 uniprotkb:O15554 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 intact:EBI-2924473|ensembl:ENSP00000496939|uniprotkb:Q53XR4 psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:kcnn4_human(display_long)|uniprotkb:KCNN4(gene name)|psi-mi:KCNN4(display_short)|uniprotkb:IK1(gene name synonym)|uniprotkb:IKCA1(gene name synonym)|uniprotkb:KCA4(gene name synonym)|uniprotkb:SK4(gene name synonym)|uniprotkb:KCa4(gene name synonym)|uniprotkb:KCa3.1(gene name synonym)|uniprotkb:IKCa1(gene name synonym)|uniprotkb:Putative Gardos channel(gene name synonym) psi-mi:"MI:1314"(proximity-dependent biotin identification) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:2364"(proximity) psi-mi:"MI:0471"(MINT) intact:EBI-27079701|imex:IM-29196-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N ensembl:ENSG00000104783(gene)|ensembl:ENST00000648319(transcript)|go:"GO:0002376"(immune system process)|go:"GO:0005267"(potassium channel activity)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005886"(plasma membrane)|go:"GO:0006811"(ion transport)|go:"GO:0006813"(potassium ion transport)|go:"GO:0006816"(calcium ion transport)|go:"GO:0006884"(cell volume homeostasis)|go:"GO:0006952"(defense response)|go:"GO:0008076"(voltage-gated potassium channel complex)|go:"GO:0015269"(calcium-activated potassium channel activity)|go:"GO:0016286"(small conductance calcium-activated potassium channel activity)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0022894"(Intermediate conductance calcium-activated potassium channel activity)|go:"GO:0030322"(stabilization of membrane potential)|go:"GO:0031982"(vesicle)|go:"GO:0043005"(neuron projection)|go:"GO:0043025"(neuronal cell body)|go:"GO:0045332"(phospholipid translocation)|go:"GO:0046541"(saliva secretion)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0071805"(potassium ion transmembrane transport)|interpro:IPR004178(Calmodulin-binding)|interpro:IPR013099(Ion transport 2)|interpro:IPR015449(Potassium channel, calcium-activated, SK)|interpro:IPR036122|rcsb pdb:6CNM|rcsb pdb:6CNN|rcsb pdb:6CNO|rcsb pdb:6D42|reactome:R-HSA-1296052|go:"GO:1901381"(positive regulation of potassium ion transmembrane transport)|refseq:NP_002241.1|dip:DIP-48598N - - - figure legend:ST1|comment:Proteins enriched from quadruplicate experiments were analyzed by high resolution MS. After subtracting the proteins identified in negative control cells we reproducibly identified 612 proteins by using the label-free quantification algorithm available in MaxQuant|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rogid:7nm4ouZmgJFq4s+0NrcNiOxz++k9606 rigid:FPv1k1iLgNG6cNfcDqW0ZeRI9Kc false fusion protein:c-c - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P35222 uniprotkb:F1PAA9 intact:EBI-491549|uniprotkb:Q8NEW9|uniprotkb:Q8NI94|uniprotkb:Q9H391|ensembl:ENSP00000344456|ensembl:ENSP00000379486|ensembl:ENSP00000379488|ensembl:ENSP00000385604|ensembl:ENSP00000387455|ensembl:ENSP00000401599|ensembl:ENSP00000409302|ensembl:ENSP00000412219|ensembl:ENSP00000493533|ensembl:ENSP00000493610|ensembl:ENSP00000494053|ensembl:ENSP00000494411|ensembl:ENSP00000494677|ensembl:ENSP00000494845|ensembl:ENSP00000494914|ensembl:ENSP00000495076|ensembl:ENSP00000495244|ensembl:ENSP00000495360|ensembl:ENSP00000495450|ensembl:ENSP00000495719|ensembl:ENSP00000495992|ensembl:ENSP00000496021|ensembl:ENSP00000496180|ensembl:ENSP00000496385|uniprotkb:A8K1L7|intact:EBI-491563 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 psi-mi:ctnb1_human(display_long)|uniprotkb:Beta-catenin(gene name synonym)|uniprotkb:OK/SW-cl.35(orf name)|uniprotkb:PRO2286(orf name)|uniprotkb:CTNNB1(gene name)|psi-mi:CTNNB1(display_short)|uniprotkb:CTNNB(gene name synonym) psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:"MI:0663"(confocal microscopy) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27080311|imex:IM-29196-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000168036(gene)|ensembl:ENST00000349496(transcript)|ensembl:ENST00000396183(transcript)|ensembl:ENST00000396185(transcript)|ensembl:ENST00000405570(transcript)|ensembl:ENST00000431914(transcript)|ensembl:ENST00000441708(transcript)|ensembl:ENST00000450969(transcript)|ensembl:ENST00000642248(transcript)|ensembl:ENST00000642315(transcript)|ensembl:ENST00000642426(transcript)|ensembl:ENST00000642992(transcript)|ensembl:ENST00000643031(transcript)|ensembl:ENST00000643297(transcript)|ensembl:ENST00000643541(transcript)|ensembl:ENST00000643977(transcript)|ensembl:ENST00000643992(transcript)|ensembl:ENST00000644867(transcript)|ensembl:ENST00000645210(transcript)|ensembl:ENST00000645320(transcript)|ensembl:ENST00000645982(transcript)|ensembl:ENST00000433400(transcript)|ensembl:ENST00000646369(transcript)|ensembl:ENST00000647390(transcript)|ensembl:ENST00000646725(transcript)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000209"(protein polyubiquitination)|go:"GO:0000578"(embryonic axis specification)|reactome:R-HSA-351906|reactome:R-HSA-3769402|reactome:R-HSA-3134973|reactome:R-HSA-381771|reactome:R-HSA-4086398|reactome:R-HSA-418990|reactome:R-HSA-4411364|reactome:R-HSA-4641262|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5339716|reactome:R-HSA-5358747|reactome:R-HSA-5358749|reactome:R-HSA-5358751|reactome:R-HSA-5358752|reactome:R-HSA-5626467|reactome:R-HSA-8853884|reactome:R-HSA-8876493|reactome:R-HSA-8951430|go:"GO:0045765"(regulation of angiogenesis)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0045976"(negative regulation of mitotic cell cycle, embryonic)|go:"GO:0046332"(SMAD binding)|go:"GO:0048145"(regulation of fibroblast proliferation)|go:"GO:0048469"(cell maturation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048489"(synaptic vesicle transport)|go:"GO:0048538"(thymus development)|go:"GO:0048599"(oocyte development)|go:"GO:0048617"(embryonic foregut morphogenesis)|go:"GO:0048643"(positive regulation of skeletal muscle tissue development)|go:"GO:0048660"(regulation of smooth muscle cell proliferation)|go:"GO:0045743"(positive regulation of fibroblast growth factor receptor signaling pathway)|go:"GO:0048715"(negative regulation of oligodendrocyte differentiation)|go:"GO:0010629"(negative regulation of gene expression)|go:"GO:0010718"(positive regulation of epithelial to mesenchymal transition)|go:"GO:0010909"(positive regulation of heparan sulfate proteoglycan biosynthetic process)|go:"GO:0016020"(membrane)|go:"GO:0016323"(basolateral plasma membrane)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016525"(negative regulation of angiogenesis)|go:"GO:0016600"(flotillin complex)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019827"(stem cell population maintenance)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0021819"(layer formation in cerebral cortex)|go:"GO:0022009"(central nervous system vasculogenesis)|go:"GO:0030018"(Z disc)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0030316"(osteoclast differentiation)|go:"GO:0030331"(estrogen receptor binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0030539"(male genitalia development)|go:"GO:0030877"(beta-catenin destruction complex)|go:"GO:0030902"(hindbrain development)|go:"GO:0030997"(regulation of centriole-centriole cohesion)|go:"GO:0031016"(pancreas development)|go:"GO:0031069"(hair follicle morphogenesis)|go:"GO:0031528"(microvillus membrane)|go:"GO:0031641"(regulation of myelination)|go:"GO:0032212"(positive regulation of telomere maintenance via telomerase)|go:"GO:0032331"(negative regulation of chondrocyte differentiation)|go:"GO:0032355"(response to estradiol)|go:"GO:0032968"(positive regulation of transcription elongation from RNA polymerase II promoter)|go:"GO:0032991"(protein-containing complex)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0033234"(negative regulation of protein sumoylation)|go:"GO:0034333"(adherens junction assembly)|go:"GO:0034394"(protein localization to cell surface)|go:"GO:0034750"(Scrib-APC-beta-catenin complex)|go:"GO:0035050"(embryonic heart tube development)|go:"GO:0035112"(genitalia morphogenesis)|go:"GO:0035115"(embryonic forelimb morphogenesis)|go:"GO:0035116"(embryonic hindlimb morphogenesis)|go:"GO:0035315"(hair cell differentiation)|go:"GO:0035995"(detection of muscle stretch)|go:"GO:0036023"(embryonic skeletal limb joint morphogenesis)|go:"GO:0036520"(astrocyte-dopaminergic neuron signaling)|go:"GO:0042129"(regulation of T cell proliferation)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042493"|go:"GO:0042733"(embryonic digit morphogenesis)|go:"GO:0042734"(presynaptic membrane)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043525"(positive regulation of neuron apoptotic process)|go:"GO:0044325"(transmembrane transporter binding)|go:"GO:0044334"(canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition)|go:"GO:0044336"(canonical Wnt signaling pathway involved in negative regulation of apoptotic process)|go:"GO:0044338"(canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation)|go:"GO:0045177"(apical part of cell)|go:"GO:0045202"(synapse)|go:"GO:0045211"(postsynaptic membrane)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045453"(bone resorption)|go:"GO:0045603"(positive regulation of endothelial cell differentiation)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0045671"(negative regulation of osteoclast differentiation)|go:"GO:0060441"(epithelial tube branching involved in lung morphogenesis)|go:"GO:0060479"(lung cell differentiation)|go:"GO:0060484"(lung-associated mesenchyme development)|go:"GO:0060492"(lung induction)|go:"GO:0050767"(regulation of neurogenesis)|go:"GO:0050808"(synapse organization)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0060742"(epithelial cell differentiation involved in prostate gland development)|go:"GO:0060769"(positive regulation of epithelial cell proliferation involved in prostate gland development)|go:"GO:0051145"(smooth muscle cell differentiation)|go:"GO:0051571"(positive regulation of histone H3-K4 methylation)|go:"GO:0051884"(regulation of timing of anagen)|go:"GO:0051973"(positive regulation of telomerase activity)|go:"GO:0060789"(hair follicle placode formation)|go:"GO:0060916"(mesenchymal cell proliferation involved in lung development)|go:"GO:0061047"(positive regulation of branching involved in lung morphogenesis)|go:"GO:0061154"(endothelial tube morphogenesis)|go:"GO:0061198"(fungiform papilla formation)|go:"GO:0061324"(canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation)|go:"GO:0061549"(sympathetic ganglion development)|go:"GO:0061550"(cranial ganglion development)|go:"GO:0060066"(oviduct development)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070369"(beta-catenin-TCF7L2 complex)|go:"GO:0070411"(I-SMAD binding)|go:"GO:0070602"(regulation of centromeric sister chromatid cohesion)|go:"GO:0071363"(cellular response to growth factor stimulus)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0071944"(cell periphery)|go:"GO:0072033"(renal vesicle formation)|go:"GO:0060070"(canonical Wnt signaling pathway)|go:"GO:0060440"(trachea formation)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0005925"(focal adhesion)|go:"GO:0005938"(cell cortex)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007268"(chemical synaptic transmission)|go:"GO:0007398"(ectoderm development)|go:"GO:0007403"(glial cell fate determination)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0005916"(fascia adherens)|go:"GO:0008134"(transcription factor binding)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009948"(anterior/posterior axis specification)|go:"GO:0009950"(dorsal/ventral axis specification)|go:"GO:0009954"(proximal/distal pattern formation)|go:"GO:0072054"(renal outer medulla development)|go:"GO:0072079"(nephron tubule formation)|go:"GO:0072182"(regulation of nephron tubule epithelial cell differentiation)|go:"GO:0090279"(regulation of calcium ion import)|go:"GO:0097091"(synaptic vesicle clustering)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098685"(Schaffer collateral - CA1 synapse)|go:"GO:0098831"(presynaptic active zone cytoplasmic component)|go:"GO:0099092"(postsynaptic density, intracellular component)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1903204"(negative regulation of oxidative stress-induced neuron death)|go:"GO:1904798"(positive regulation of core promoter binding)|go:"GO:1904888"(cranial skeletal system development)|go:"GO:1904948"(midbrain dopaminergic neuron differentiation)|go:"GO:1904954"(canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990226"(histone methyltransferase binding)|go:"GO:1990403"(embryonic brain development)|go:"GO:1990791"(dorsal root ganglion development)|go:"GO:1990907"(beta-catenin-TCF complex)|go:"GO:1990909"(Wnt signalosome)|go:"GO:2000008"(regulation of protein localization to cell surface)|go:"GO:2000017"(positive regulation of determination of dorsal identity)|go:"GO:2001234"(negative regulation of apoptotic signaling pathway)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|mint:P35222|rcsb pdb:1G3J|rcsb pdb:1JDH|rcsb pdb:1JPW|rcsb pdb:1LUJ|rcsb pdb:1P22|rcsb pdb:1QZ7|rcsb pdb:1T08|rcsb pdb:1TH1|rcsb pdb:2G57|rcsb pdb:2GL7|rcsb pdb:2Z6H|rcsb pdb:3DIW|rcsb pdb:3FQN|rcsb pdb:3FQR|rcsb pdb:3SL9|rcsb pdb:3SLA|rcsb pdb:3TX7|rcsb pdb:4DJS|rcsb pdb:6M90|rcsb pdb:6M91|rcsb pdb:6M92|rcsb pdb:6M93|rcsb pdb:6M94|rcsb pdb:6O9B|rcsb pdb:6O9C|rcsb pdb:6WLX|rcsb pdb:6WNX|rcsb pdb:7AFW|go:"GO:0072053"(renal inner medulla development)|rcsb pdb:7AR4|reactome:R-HSA-195253|reactome:R-HSA-196299|reactome:R-HSA-201681|reactome:R-HSA-201722|go:"GO:0000791"(euchromatin)|go:"GO:0000922"(spindle pole)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0001569"(branching involved in blood vessel morphogenesis)|go:"GO:0001658"(branching involved in ureteric bud morphogenesis)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0001702"(gastrulation with mouth forming second)|go:"GO:0001708"(cell fate specification)|go:"GO:0001711"(endodermal cell fate commitment)|go:"GO:0001764"(neuron migration)|go:"GO:0001837"(epithelial to mesenchymal transition)|go:"GO:0001840"(neural plate development)|go:"GO:0002052"(positive regulation of neuroblast proliferation)|go:"GO:0002053"(positive regulation of mesenchymal cell proliferation)|go:"GO:0002089"(lens morphogenesis in camera-type eye)|go:"GO:0003266"(regulation of secondary heart field cardioblast proliferation)|go:"GO:0003338"(metanephros morphogenesis)|go:"GO:0003340"(negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis)|go:"GO:0003682"(chromatin binding)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005667"(transcription regulator complex)|go:"GO:0000904"(cell morphogenesis involved in differentiation)|dip:DIP-122N|refseq:NP_001091679.1|refseq:NP_001091680.1|refseq:NP_001895.1|refseq:XP_005264943.1|refseq:XP_016861227.1 ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0071944"(cell periphery) - - figure legend:F5C F5D F6D|comment:cortical localization was seen in EGTA-treated cells and EGTA-untreated cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:WLs7+T0WG4DiBStdS5+lR7i83dk9606 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rigid:mY1eE8pobhxZzQoFD6vWtMZA/KY false - fusion protein:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P46940 uniprotkb:F1PAA9 intact:EBI-297509|ensembl:ENSP00000268182|uniprotkb:A7MBM3 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 psi-mi:iqga1_human(display_long)|uniprotkb:IQGAP1(gene name)|psi-mi:IQGAP1(display_short)|uniprotkb:KIAA0051(gene name synonym)|uniprotkb:p195(gene name synonym) psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:"MI:0663"(confocal microscopy) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27080319|imex:IM-29196-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000140575(gene)|go:"GO:0005516"(calmodulin binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005874"(microtubule)|go:"GO:0005884"(actin filament)|go:"GO:0005886"(plasma membrane)|ensembl:ENST00000268182(transcript)|go:"GO:0001726"(ruffle)|go:"GO:0005925"(focal adhesion)|go:"GO:0007165"(signal transduction)|go:"GO:0007173"(epidermal growth factor receptor signaling pathway)|go:"GO:0005078"(MAP-kinase scaffold activity)|go:"GO:0005095"(GTPase inhibitor activity)|go:"GO:0007346"(regulation of mitotic cell cycle)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0016477"(cell migration)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0005509"(calcium ion binding)|go:"GO:0030424"(axon)|go:"GO:0030426"(growth cone)|go:"GO:0030496"(midbody)|go:"GO:0031234"(extrinsic component of cytoplasmic side of plasma membrane)|go:"GO:0031267"(small GTPase binding)|go:"GO:0032956"(regulation of actin cytoskeleton organization)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036057"(slit diaphragm)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0043005"(neuron projection)|go:"GO:0043087"(regulation of GTPase activity)|go:"GO:0043406"(positive regulation of MAP kinase activity)|go:"GO:0043410"(positive regulation of MAPK cascade)|go:"GO:0043539"(protein serine/threonine kinase activator activity)|go:"GO:0044548"(S100 protein binding)|go:"GO:0045121"(membrane raft)|go:"GO:0045296"(cadherin binding)|go:"GO:0045860"(positive regulation of protein kinase activity)|go:"GO:0051015"(actin filament binding)|go:"GO:0051019"(mitogen-activated protein kinase binding)|go:"GO:0051894"(positive regulation of focal adhesion assembly)|go:"GO:0060090"(molecular adaptor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071277"(cellular response to calcium ion)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:0072015"(glomerular visceral epithelial cell development)|go:"GO:1900006"(positive regulation of dendrite development)|go:"GO:1900086"(positive regulation of peptidyl-tyrosine autophosphorylation)|go:"GO:1903829"(positive regulation of protein localization)|go:"GO:1904754"(positive regulation of vascular associated smooth muscle cell migration)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990776"(response to angiotensin)|interpro:IPR000048(IQ calmodulin-binding region)|go:"GO:0030667"(secretory granule membrane)|interpro:IPR000593(RasGAP protein, C-terminal)|interpro:IPR001202(WW/Rsp5/WWP)|interpro:IPR001715(Calponin-like actin-binding)|interpro:IPR001936(Ras GTPase-activating protein)|interpro:IPR008936(Rho GTPase activation protein)|interpro:IPR023152|interpro:IPR027417|interpro:IPR036872|mint:P46940|rcsb pdb:1X0H|rcsb pdb:2RR8|rcsb pdb:3FAY|rcsb pdb:3I6X|rcsb pdb:5L0O|reactome:R-HSA-373753|reactome:R-HSA-381676|reactome:R-HSA-5626467|reactome:R-HSA-5674135|reactome:R-HSA-6798695|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8980692|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013404|reactome:R-HSA-9013406|reactome:R-HSA-9013420|reactome:R-HSA-9013424|reactome:R-HSA-9649948|reactome:R-HSA-9656223|refseq:NP_003861.1|dip:DIP-32597N ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0071944"(cell periphery) - - figure legend:F5C F5D F6D|comment:cortical localization was seen in EGTA-treated cells and EGTA-untreated cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:nXO2Z6Qn8EQGfziT8dnWz1pbK/w9606 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rigid:taC8hU4zUqQvEbw9BGGerWhmKeU false - fusion protein:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P35221 uniprotkb:F1PAA9 intact:EBI-701918|uniprotkb:Q12795|intact:EBI-7950809|intact:MINT-4924748|uniprotkb:Q8N1C0|ensembl:ENSP00000304669 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 psi-mi:ctna1_human(display_long)|uniprotkb:Cadherin-associated protein(gene name synonym)|uniprotkb:Alpha E-catenin(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-13(gene name synonym)|uniprotkb:CTNNA1(gene name)|psi-mi:CTNNA1(display_short) psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:"MI:0663"(confocal microscopy) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27080327|imex:IM-29196-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_001894.2|refseq:NP_001277236.1|refseq:NP_001277238.1|refseq:NP_001277239.1|refseq:NP_001277241.1|refseq:NP_001310911.1|refseq:NP_001310912.1|refseq:NP_001310913.1|refseq:NP_001310916.1|refseq:NP_001310917.1|refseq:NP_001310918.1|refseq:NP_001310919.1|refseq:NP_001310920.1|refseq:NP_001310921.1|refseq:NP_001310922.1|refseq:NP_001310923.1|refseq:NP_001310924.1|refseq:NP_001310925.1|refseq:NP_001310926.1|refseq:NP_001310927.1|refseq:NP_001310928.1|refseq:NP_001310929.1|dip:DIP-515N|ensembl:ENSG00000044115(gene)|ensembl:ENST00000302763(transcript)|go:"GO:0001541"(ovarian follicle development)|go:"GO:0001669"(acrosomal vesicle)|go:"GO:0003723"(RNA binding)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0007015"(actin filament organization)|go:"GO:0007155"(cell adhesion)|go:"GO:0007163"(establishment or maintenance of cell polarity)|go:"GO:0007406"(negative regulation of neuroblast proliferation)|go:"GO:0007568"(aging)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0008584"(male gonad development)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016264"(gap junction assembly)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016600"(flotillin complex)|go:"GO:0017166"(vinculin binding)|go:"GO:0030027"(lamellipodium)|go:"GO:0030054"(cell junction)|go:"GO:0031103"(axon regeneration)|go:"GO:0034613"(cellular protein localization)|go:"GO:0042475"(odontogenesis of dentin-containing tooth)|go:"GO:0042802"(identical protein binding)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0043297"(apical junction assembly)|go:"GO:0043627"(response to estrogen)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045880"(positive regulation of smoothened signaling pathway)|go:"GO:0051015"(actin filament binding)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0090136"(epithelial cell-cell adhesion)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:1900181"(negative regulation of protein localization to nucleus)|go:"GO:2000146"(negative regulation of cell motility)|go:"GO:2001045"(negative regulation of integrin-mediated signaling pathway)|go:"GO:2001240"(negative regulation of extrinsic apoptotic signaling pathway in absence of ligand)|go:"GO:2001241"(positive regulation of extrinsic apoptotic signaling pathway in absence of ligand)|interpro:IPR000633(Vinculin, conserved site)|interpro:IPR001033(Alpha-catenin)|interpro:IPR006077(Vinculin/alpha-catenin)|interpro:IPR030047|interpro:IPR036723|mint:P35221|rcsb pdb:1H6G|rcsb pdb:4EHP|rcsb pdb:4IGG|rcsb pdb:6UPV|rcsb pdb:6V2O|rcsb pdb:6V2P|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-525793|reactome:R-HSA-5626467 ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0071944"(cell periphery) - - figure legend:F5C F5D F6D|comment:cortical localization was seen in EGTA-treated cells and EGTA-untreated cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:N5rM8wI4ep+iZcnXU2g5wlJmJao9606 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rigid:s6lZke5bgAxlwnfDKD9nFKharuQ false - fusion protein:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry) uniprotkb:P14923 uniprotkb:F1PAA9 intact:EBI-702484|uniprotkb:Q15093|intact:EBI-988999|intact:EBI-744449|uniprotkb:Q9HCX9|uniprotkb:Q15151|uniprotkb:Q7L3S5|uniprotkb:Q86W21|uniprotkb:Q9BWC4|ensembl:ENSP00000311113|ensembl:ENSP00000377507|ensembl:ENSP00000377508 intact:EBI-15603992|ensembl:ENSCAFP00000030112|ensembl:ENSCAFP00030023171|ensembl:ENSCAFP00040017722 psi-mi:plak_human(display_long)|uniprotkb:JUP(gene name)|psi-mi:JUP(display_short)|uniprotkb:DP3(gene name synonym)|uniprotkb:CTNNG(gene name synonym)|uniprotkb:Desmoplakin-3(gene name synonym)|uniprotkb:Desmoplakin III(gene name synonym)|uniprotkb:Catenin gamma(gene name synonym) psi-mi:cadh1_canlf(display_long)|uniprotkb:Epithelial cadherin(gene name synonym)|uniprotkb:Uvomorulin(gene name synonym)|uniprotkb:CDH1(gene name)|psi-mi:CDH1(display_short) psi-mi:"MI:0663"(confocal microscopy) Guo et al. (2014) imex:IM-29196|pubmed:25468996 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9615(canlf)|taxid:9615("Canis familiaris (dog)") psi-mi:"MI:0403"(colocalization) psi-mi:"MI:0471"(MINT) intact:EBI-27080335|imex:IM-29196-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0497"(neutral component) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_002221.1|refseq:NP_068831.1|refseq:XP_011523055.1|refseq:XP_011523057.1|refseq:XP_011523058.1|refseq:XP_011523059.1|refseq:XP_011523060.1|refseq:XP_006721936.1|refseq:XP_006721937.1|refseq:XP_006721938.1|refseq:XP_006721941.1|refseq:XP_016880079.1|dip:DIP-36235N|ensembl:ENSG00000173801(gene)|ensembl:ENST00000310706(transcript)|ensembl:ENST00000393930(transcript)|ensembl:ENST00000393931(transcript)|go:"GO:0001533"(cornified envelope)|go:"GO:0001954"(positive regulation of cell-matrix adhesion)|go:"GO:0002159"(desmosome assembly)|go:"GO:0003713"(transcription coactivator activity)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005882"(intermediate filament)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0005915"(zonula adherens)|go:"GO:0005916"(fascia adherens)|go:"GO:0005925"(focal adhesion)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0014704"(intercalated disc)|go:"GO:0015629"(actin cytoskeleton)|go:"GO:0016327"(apicolateral plasma membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016477"(cell migration)|go:"GO:0016922"(nuclear receptor binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030018"(Z disc)|go:"GO:0030057"(desmosome)|go:"GO:0032993"(protein-DNA complex)|go:"GO:0035580"(specific granule lumen)|go:"GO:0042127"(regulation of cell population proliferation)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043537"(negative regulation of blood vessel endothelial cell migration)|go:"GO:0043588"(skin development)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045294"(alpha-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0050839"(cell adhesion molecule binding)|go:"GO:0050982"(detection of mechanical stimulus)|go:"GO:0051091"(positive regulation of DNA-binding transcription factor activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071603"(endothelial cell-cell adhesion)|go:"GO:0071665"(gamma-catenin-TCF7L2 complex)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0086073"(bundle of His cell-Purkinje myocyte adhesion involved in cell communication)|go:"GO:0086083"(cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication)|go:"GO:0086091"(regulation of heart rate by cardiac conduction)|go:"GO:0090263"(positive regulation of canonical Wnt signaling pathway)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0098911"(regulation of ventricular cardiac muscle cell action potential)|go:"GO:0106006"(cytoskeletal protein-membrane anchor activity)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR000225(Armadillo)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013284(Beta-catenin)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR030461|mint:P14923|rcsb pdb:3IFQ|reactome:R-HSA-418990|reactome:R-HSA-5218920|reactome:R-HSA-6798695|reactome:R-HSA-6805567|reactome:R-HSA-6809371|reactome:R-HSA-8980692|reactome:R-HSA-9013026|reactome:R-HSA-9013106|reactome:R-HSA-9013148|reactome:R-HSA-9013406|reactome:R-HSA-9013407|reactome:R-HSA-9013409 ensembl:ENSCAFG00000020305(gene)|ensembl:ENSCAFG00030014198(gene)|ensembl:ENSCAFG00040010861(gene)|ensembl:ENSCAFT00000032337(transcript)|ensembl:ENSCAFT00030026548(transcript)|ensembl:ENSCAFT00040020426(transcript)|go:"GO:0005509"(calcium ion binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005886"(plasma membrane)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005912"(adherens junction)|go:"GO:0007156"(homophilic cell adhesion via plasma membrane adhesion molecules)|go:"GO:0007416"(synapse assembly)|go:"GO:0008013"(beta-catenin binding)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016021"(integral component of membrane)|go:"GO:0016328"(lateral plasma membrane)|go:"GO:0016342"(catenin complex)|go:"GO:0016600"(flotillin complex)|go:"GO:0022408"(negative regulation of cell-cell adhesion)|go:"GO:0030027"(lamellipodium)|go:"GO:0030336"(negative regulation of cell migration)|go:"GO:0030506"(ankyrin binding)|go:"GO:0030864"(cortical actin cytoskeleton)|go:"GO:0032794"(GTPase activating protein binding)|go:"GO:0034332"(adherens junction organization)|go:"GO:0042307"(positive regulation of protein import into nucleus)|go:"GO:0042802"(identical protein binding)|go:"GO:0043296"(apical junction complex)|go:"GO:0045295"(gamma-catenin binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0071285"(cellular response to lithium ion)|go:"GO:0071681"(cellular response to indole-3-methanol)|go:"GO:0072659"(protein localization to plasma membrane)|go:"GO:0098742"(cell-cell adhesion via plasma-membrane adhesion molecules)|interpro:IPR000233(Cadherin cytoplasmic region)|interpro:IPR002126(Cadherin)|interpro:IPR014868(Cadherin prodomain like)|interpro:IPR015919(Cadherin-like)|interpro:IPR020894|interpro:IPR027397|interpro:IPR030049|interpro:IPR039808|reactome:R-CFA-1474228|reactome:R-CFA-216083|reactome:R-CFA-351906|reactome:R-CFA-418990|reactome:R-CFA-5626467|refseq:NP_001274054.1|dip:DIP-61284N go:"GO:0071944"(cell periphery) - - figure legend:F5C F5D F6D|comment:cortical localization was seen in EGTA-treated cells and EGTA-untreated cells.|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-mkn28)|taxid:9606(human mkn28) - 2021/07/28 2021/09/03 rogid:qOBUlbifyKUk1xF0Zr9jZPkZozc9606 rogid:m6j0SWep4E0/+JgvWmLSimUb3ng9615 rigid:Oewitod5YU1zR5q58ooxbt1vyo4 false - fusion protein:c-c - - psi-mi:"MI:1200"(immunocytochemistry) psi-mi:"MI:1200"(immunocytochemistry)