#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q567U6	uniprotkb:Q8N668	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26995998|imex:IM-29015-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2A, Supp. Figs. 4C, 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q7Z3J2	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26995998|imex:IM-29015-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2A, Supp. Figs. 4C, 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:O60826	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26995998|imex:IM-29015-41	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 2A, Supp. Figs. 4C, 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q8N668	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996003|imex:IM-29015-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2A, Supp. Figs. 4B, 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q7Z3J2	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996003|imex:IM-29015-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2A, Supp. Figs. 4B, 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q567U6	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996003|imex:IM-29015-21	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 2A, Supp. Figs. 4B, 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z3J2	uniprotkb:Q8N668	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996008|imex:IM-29015-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2A, Supp. Fig. 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z3J2	uniprotkb:O60826	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996008|imex:IM-29015-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 2A, Supp. Fig. 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q7Z3J2	uniprotkb:Q567U6	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996008|imex:IM-29015-23	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 2A, Supp. Fig. 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q7Z4G1	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550081|uniprotkb:A6NF28|uniprotkb:Q5TBK4|uniprotkb:B7ZLN0|ensembl:ENSP00000366841|ensembl:ENSP00000506987	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd6_human(display_long)|uniprotkb:COMMD6(gene name)|psi-mi:COMMD6(display_short)|uniprotkb:MSTP076(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996022|imex:IM-29015-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_987091.1|refseq:NP_987093.1|ensembl:ENSG00000188243(gene)|ensembl:ENST00000377615(transcript)|ensembl:ENST00000682242(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR017920|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:73rTIbUABTRqe9OabTgdQ1QvZ7A9606	rigid:giIG1pv7y9g4Wm/CxkpkWXKPZ4s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q8N668	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996022|imex:IM-29015-43	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:giIG1pv7y9g4Wm/CxkpkWXKPZ4s	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N668	uniprotkb:Q7Z3J2	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996066|imex:IM-29015-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2C, Supp. Fig. 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N668	uniprotkb:Q567U6	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996066|imex:IM-29015-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 2C, Supp. Fig. 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N668	uniprotkb:O60826	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996066|imex:IM-29015-45	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 2C, Supp. Fig. 6A|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q7Z3J2	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996224|imex:IM-29015-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 3B|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:O60826	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996224|imex:IM-29015-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 3B|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996224|imex:IM-29015-47	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 3B|comment:"The complex also contains member(s) of the WASH family of proteins"|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q8N668	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996502|imex:IM-29015-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 4B|comment:Interaction observed in the absence of CCDC93|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:mv/JR6kIq9kAeNJb9wWahBrKM5A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q7Z3J2	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996502|imex:IM-29015-35	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Supp. Fig. 4B|comment:Interaction observed in the absence of CCDC93|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:mv/JR6kIq9kAeNJb9wWahBrKM5A	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9Y6K9	uniprotkb:O15111	intact:EBI-81279|intact:EBI-356130|uniprotkb:Q7LBY6|uniprotkb:Q7Z7F1|ensembl:ENSP00000471166|ensembl:ENSP00000479662	intact:EBI-81249|uniprotkb:O14666|uniprotkb:Q13132|uniprotkb:Q5W0I4|uniprotkb:Q92467|ensembl:ENSP00000359424|intact:EBI-28970970	psi-mi:nemo_human(display_long)|uniprotkb:IKBKG(gene name)|psi-mi:IKBKG(display_short)|uniprotkb:FIP3(gene name synonym)|uniprotkb:NEMO(gene name synonym)|uniprotkb:NF-kappa-B essential modifier(gene name synonym)|uniprotkb:Inhibitor of nuclear factor kappa-B kinase subunit gamma(gene name synonym)|uniprotkb:IkB kinase-associated protein 1(gene name synonym)|uniprotkb:FIP-3(gene name synonym)	psi-mi:ikka_human(display_long)|uniprotkb:CHUK(gene name)|psi-mi:CHUK(display_short)|uniprotkb:IKKA(gene name synonym)|uniprotkb:TCF16(gene name synonym)|uniprotkb:I-kappa-B kinase 1(gene name synonym)|uniprotkb:Conserved helix-loop-helix ubiquitous kinase(gene name synonym)|uniprotkb:Nuclear factor NF-kappa-B inhibitor kinase alpha(gene name synonym)|uniprotkb:Transcription factor 16(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996515|imex:IM-29015-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001308325.1|refseq:NP_001308326.1|refseq:NP_001093326.2|refseq:NP_001093327.1|refseq:NP_001138727.1|refseq:NP_003630.1|dip:DIP-27528N|ensembl:ENSG00000269335(gene)|ensembl:ENST00000594239(transcript)|ensembl:ENST00000611071(transcript)|go:"GO:0000151"(ubiquitin ligase complex)|go:"GO:0000922"(spindle pole)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006915"(apoptotic process)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0016239"(positive regulation of macroautophagy)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0042975"(peroxisome proliferator activated receptor binding)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043276"(anoikis)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046872"(metal ion binding)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0050852"(T cell receptor signaling pathway)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051650"(establishment of vesicle localization)|go:"GO:0065003"(protein-containing complex assembly)|go:"GO:0070530"(K63-linked polyubiquitin modification-dependent protein binding)|go:"GO:0072686"(mitotic spindle)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1990450"(linear polyubiquitin binding)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR021063|interpro:IPR032419|interpro:IPR034735|mint:Q9Y6K9|rcsb pdb:2JVX|rcsb pdb:2JVY|rcsb pdb:3BRT|rcsb pdb:3BRV|rcsb pdb:3CL3|rcsb pdb:3FX0|rcsb pdb:4BWN|rcsb pdb:5AAY|rcsb pdb:5LDE|rcsb pdb:6MI3|rcsb pdb:6MI4|rcsb pdb:6YEK|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-450302|reactome:R-HSA-450321|reactome:R-HSA-4755510|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607764|reactome:R-HSA-5684264|reactome:R-HSA-5689880|reactome:R-HSA-5689896|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144	refseq:NP_001269.3|ensembl:ENSP00000359424|ensembl:ENSG00000213341(gene)|ensembl:ENST00000370397(transcript)|go:"GO:0003009"(skeletal muscle contraction)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006954"(inflammatory response)|go:"GO:0006955"(immune response)|go:"GO:0007249"(I-kappaB kinase/NF-kappaB signaling)|go:"GO:0007252"(I-kappaB phosphorylation)|go:"GO:0007266"(Rho protein signal transduction)|go:"GO:0008384"(IkappaB kinase activity)|go:"GO:0008385"(IkappaB kinase complex)|go:"GO:0009615"(response to virus)|go:"GO:0009636"(response to toxic substance)|go:"GO:0009653"(anatomical structure morphogenesis)|go:"GO:0009898"(cytoplasmic side of plasma membrane)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0032727"(positive regulation of interferon-alpha production)|go:"GO:0033194"(response to hydroperoxide)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0035631"(CD40 receptor complex)|go:"GO:0038061"(NIK/NF-kappaB signaling)|go:"GO:0042493"|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043200"(response to amino acid)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045087"(innate immune response)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0046982"(protein heterodimerization activity)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051146"(striated muscle cell differentiation)|go:"GO:0061847"(response to cholecystokinin)|go:"GO:0071276"(cellular response to cadmium ion)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0098586"(cellular response to virus)|go:"GO:1990459"(transferrin receptor binding)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|go:"GO:0010034"(response to acetate)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR022007|interpro:IPR041185|mint:O15111|rcsb pdb:3BRT|rcsb pdb:5EBZ|rcsb pdb:5TQW|rcsb pdb:5TQX|rcsb pdb:5TQY|reactome:R-HSA-1169091|reactome:R-HSA-1236974|reactome:R-HSA-168638|reactome:R-HSA-168927|reactome:R-HSA-1810476|reactome:R-HSA-198323|reactome:R-HSA-202424|reactome:R-HSA-2871837|reactome:R-HSA-445989|reactome:R-HSA-5357905|reactome:R-HSA-5357956|reactome:R-HSA-5602636|reactome:R-HSA-5603027|reactome:R-HSA-5603029|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5674400|reactome:R-HSA-5676590|reactome:R-HSA-5684264|reactome:R-HSA-9020702|reactome:R-HSA-933542|reactome:R-HSA-933543|reactome:R-HSA-937039|reactome:R-HSA-937041|reactome:R-HSA-975144|dip:DIP-27526N	-	-	-	figure legend:Supp. Figs. 6A, 11|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:9OeZIMeJvNtDEMoiLaKwVEpxSSM9606	rogid:FVB/gXjSBTB9hdq9pycQogxesms9606	rigid:Qf2i/YNO6n0jRGC5FBlR7ahqqUw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q8N668	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996077|imex:IM-29015-61	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q7Z3J2	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996077|imex:IM-29015-61	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:O60826	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996077|imex:IM-29015-61	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q567U6	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996083|imex:IM-29015-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:BnX5Ar47jMGDOmf28EC3ULWaWKo	false	-	sufficient binding region:207-431|ha tag:n-n	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q8N668	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996101|imex:IM-29015-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/09/10	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:1AjuePNI2W9BXGJI5sWWA58ymME	false	sufficient binding region:1-430|ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:O60826	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996101|imex:IM-29015-25	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 2F|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/09/10	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:1AjuePNI2W9BXGJI5sWWA58ymME	false	sufficient binding region:1-430|ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q8N668	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996177|imex:IM-29015-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q7Z3J2	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996177|imex:IM-29015-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 2G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q567U6	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996177|imex:IM-29015-3	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 2G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:2TVwVWtPt9p1MYOWR1MJyXB6g7o	false	ha tag:n-n	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8N668	uniprotkb:O60826	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996185|imex:IM-29015-27	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 2G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:T7MOjJTJ0+NL0mpI+mtI2G9IgeI	false	-	ha tag:n-n|sufficient binding region:1-321	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q8N668	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996193|imex:IM-29015-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 2G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:1AjuePNI2W9BXGJI5sWWA58ymME	false	ha tag:n-n|sufficient binding region:1-447	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q567U6	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996193|imex:IM-29015-5	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 2G|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/15	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:1AjuePNI2W9BXGJI5sWWA58ymME	false	ha tag:n-n|sufficient binding region:1-447	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q7Z3J2	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996324|imex:IM-29015-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	sufficient binding region:672-1341|necessary binding region:672-741|ha tag:?-?|yellow fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996324|imex:IM-29015-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	sufficient binding region:672-1341|necessary binding region:672-741|ha tag:?-?|yellow fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:O60826	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996324|imex:IM-29015-7	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	sufficient binding region:672-1341|necessary binding region:672-741|ha tag:?-?|yellow fluorescent protein tag:?-?	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q8N668	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996238|imex:IM-29015-63	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:YQYCDz7OaMVbPNonFYU+0RPY+8g	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q7Z3J2	uniprotkb:Q8N668	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996242|imex:IM-29015-29	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Fig. 3C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/16	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:i7WQWLvcum1iUN8b81jIypwzY5Q	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q8N668	uniprotkb:Q96QK1	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0663"(confocal microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997490|imex:IM-29015-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	figure legend:Supp. Fig. 9C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:EXkMduDQKNCdp876vGF5vna9t389606	rigid:zjXLrc3I+85efCEQOMZIeBRULTc	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q8N668	uniprotkb:Q641Q2	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:"MI:0663"(confocal microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997490|imex:IM-29015-19	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	-	-	-	figure legend:Supp. Fig. 9C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rigid:zjXLrc3I+85efCEQOMZIeBRULTc	false	-	-	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996246|imex:IM-29015-31	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 5D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:uMD9Z8E3v70F/5WqeY1I3dZyhgQ	false	-	sufficient binding region:207-431|ha tag:n-n|sufficient binding region:411-631	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q641Q2	uniprotkb:O60826	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996277|imex:IM-29015-49	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Fig. 5E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:rh69Z8hruDBeUh4+lycijTtw+C8	false	-	ha tag:n-n|sufficient binding region:1-447|sufficient binding region:321-627	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q567U6	uniprotkb:Q8N668	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996429|imex:IM-29015-53	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:YQYCDz7OaMVbPNonFYU+0RPY+8g	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q86X83	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550220|uniprotkb:Q9H3L5|uniprotkb:Q9Y5V1|uniprotkb:Q561V4|ensembl:ENSP00000419475	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd2_human(display_long)|uniprotkb:COMMD2(gene name)|psi-mi:COMMD2(display_short)|uniprotkb:HSPC042(orf name)|uniprotkb:My004(orf name)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996435|imex:IM-29015-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_057178.2|ensembl:ENSG00000114744(gene)|ensembl:ENST00000473414(transcript)|go:"GO:0005737"(cytoplasm)|interpro:IPR017920|interpro:IPR037354|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:407iXgoqRlBDNBmFvM9pGqZ4esI9606	rigid:6Dfdu6tVwm3vWUzkTYVe18w5CJE	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q9UBI1	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-714979|uniprotkb:Q5T8Y9|uniprotkb:D3DRU7|ensembl:ENSP00000366032	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd3_human(display_long)|uniprotkb:Protein Bup(gene name synonym)|uniprotkb:Protein PIL(gene name synonym)|uniprotkb:COMMD3(gene name)|psi-mi:COMMD3(display_short)|uniprotkb:BUP(gene name synonym)|uniprotkb:C10orf8(gene name synonym)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996441|imex:IM-29015-81	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_036203.1|ensembl:ENSG00000148444(gene)|ensembl:ENST00000376836(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005634"(nucleus)|go:"GO:0006814"(sodium ion transport)|interpro:IPR017920|interpro:IPR037355|reactome:R-HSA-6798695|reactome:R-HSA-8951664|go:"GO:1904813"(ficolin-1-rich granule lumen)	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:t9j9U/cA+1XMiybcmixYycqq/nE9606	rigid:ymxlPwdmmwdqKr5cxwk/UlypbHw	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q9H0A8	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550064|uniprotkb:Q7L637|uniprotkb:Q9NX43|uniprotkb:B2RBN4|uniprotkb:H3BUL2|ensembl:ENSP00000267935|ensembl:ENSP00000433662	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd4_human(display_long)|uniprotkb:COMMD4(gene name)|psi-mi:COMMD4(display_short)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996447|imex:IM-29015-55	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_001271306.1|refseq:NP_060298.2|refseq:NP_001271307.1|ensembl:ENSG00000140365(gene)|ensembl:ENST00000267935(transcript)|ensembl:ENST00000480484(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR017920|interpro:IPR037356|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:v1pkDNc18f7sZM/89Gv0bho9GN89606	rigid:N8096oSqlb0hwukqqqLnwDs+mHU	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q9GZQ3	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550256|uniprotkb:Q9NVN6|uniprotkb:Q9UHX5|uniprotkb:D3DWN7|ensembl:ENSP00000304544|ensembl:ENSP00000385793|ensembl:ENSP00000394331|ensembl:ENSP00000445840	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd5_human(display_long)|uniprotkb:COMMD5(gene name)|psi-mi:COMMD5(display_short)|uniprotkb:HT002(orf name)|uniprotkb:Hypertension-related calcium-regulated gene protein(gene name synonym)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996453|imex:IM-29015-57	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_001274166.1|refseq:NP_001074472.1|refseq:NP_001074473.1|refseq:NP_054785.2|ensembl:ENSG00000170619(gene)|ensembl:ENST00000305103(transcript)|ensembl:ENST00000402718(transcript)|ensembl:ENST00000450361(transcript)|ensembl:ENST00000543949(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|interpro:IPR037357|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:twwnNUW5VEZumbVyPVv9WAIwvgQ9606	rigid:QgohDyD+MHvqLFHh7TZlK+PPxg4	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q7Z4G1	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550081|uniprotkb:A6NF28|uniprotkb:Q5TBK4|uniprotkb:B7ZLN0|ensembl:ENSP00000366841|ensembl:ENSP00000506987	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd6_human(display_long)|uniprotkb:COMMD6(gene name)|psi-mi:COMMD6(display_short)|uniprotkb:MSTP076(orf name)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996459|imex:IM-29015-67	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_987091.1|refseq:NP_987093.1|ensembl:ENSG00000188243(gene)|ensembl:ENST00000377615(transcript)|ensembl:ENST00000682242(transcript)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR017920|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:73rTIbUABTRqe9OabTgdQ1QvZ7A9606	rigid:6mJqe4jfloTaewGGRH8O7kWSmC8	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q86VX2	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550280|uniprotkb:A2BHJ2|uniprotkb:Q5JYB0|uniprotkb:Q96SI7|uniprotkb:Q9BW53|uniprotkb:B3KTZ2|ensembl:ENSP00000278980	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd7_human(display_long)|uniprotkb:COMMD7(gene name)|psi-mi:COMMD7(display_short)|uniprotkb:C20orf92(gene name synonym)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996465|imex:IM-29015-33	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_001092809.1|refseq:NP_444269.2|ensembl:ENSG00000149600(gene)|ensembl:ENST00000278980(transcript)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0033209"(tumor necrosis factor-mediated signaling pathway)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0051059"(NF-kappaB binding)|interpro:IPR017920|interpro:IPR037358|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:9mVwUwXsqGS+xFwRa4KbMylvaps9606	rigid:yHe7ld5tDvBgvlclY+VxzkjCU8o	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q9NX08	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-725694|uniprotkb:Q8WUR4|uniprotkb:Q9HC15|ensembl:ENSP00000370984	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd8_human(display_long)|uniprotkb:COMMD8(gene name)|psi-mi:COMMD8(display_short)|uniprotkb:MDS022(orf name)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996471|imex:IM-29015-69	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_060315.1|ensembl:ENSG00000169019(gene)|ensembl:ENST00000381571(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|interpro:IPR017920|mint:Q9NX08|reactome:R-HSA-8951664|refseq:NP_001316597.1	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:m3HKrdrtTRNJyCfMBLOZCaZRexg9606	rigid:a8IBG/BchFQgyFlPtEIQrnxJNpk	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q9P000	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550510|uniprotkb:Q9H0R0|uniprotkb:Q96FI2|uniprotkb:E9PAN2|ensembl:ENSP00000263401	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd9_human(display_long)|uniprotkb:COMMD9(gene name)|psi-mi:COMMD9(display_short)|uniprotkb:HSPC166(orf name)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996477|imex:IM-29015-71	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_054905.2|refseq:NP_001294866.1|ensembl:ENSG00000110442(gene)|ensembl:ENST00000263401(transcript)|go:"GO:0005576"(extracellular region)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0006814"(sodium ion transport)|go:"GO:0034774"(secretory granule lumen)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:1904813"(ficolin-1-rich granule lumen)|interpro:IPR017920|interpro:IPR037360|rcsb pdb:4NKN|rcsb pdb:4OE9|rcsb pdb:6BP6|reactome:R-HSA-6798695|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:2MhNQZU+OGXGZ2nuSi1AS8+bpz09606	rigid:7m0jippwZq7PA+QjklwzoFmgdMs	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q9Y6G5	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550310|uniprotkb:Q9P077|uniprotkb:D3DT07|ensembl:ENSP00000274458	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comda_human(display_long)|uniprotkb:COMMD10(gene name)|psi-mi:COMMD10(display_short)|uniprotkb:HSPC305(orf name)|uniprotkb:PTD002(orf name)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996483|imex:IM-29015-59	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_057228.1|refseq:NP_001295009.1|ensembl:ENSG00000145781(gene)|ensembl:ENST00000274458(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|interpro:IPR017920|interpro:IPR037361|mint:Q9Y6G5|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 3A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/06/15	2021/06/16	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:yRozKabxLJMAEbM9QfLGOQCzRxE9606	rigid:TWaAjWle67syKe7uEdX66OT58dY	false	-	glutathione s tranferase tag:?-?	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996381|imex:IM-29015-65	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:uMD9Z8E3v70F/5WqeY1I3dZyhgQ	false	glutathione s tranferase tag:n-n|sufficient binding region:356-600	maltose binding protein tag:?-?|sufficient binding region:411-631	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:O60826	uniprotkb:Q567U6	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996489|imex:IM-29015-83	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Supp Fig. 4A|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/06/15	2021/06/16	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:BnX5Ar47jMGDOmf28EC3ULWaWKo	false	glutathione s tranferase tag:n-n|sufficient binding region:1-447	maltose binding protein tag:?-?|sufficient binding region:1-430	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0096"(pull down)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996397|imex:IM-29015-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 6D|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:uMD9Z8E3v70F/5WqeY1I3dZyhgQ	false	glutathione s tranferase tag:n-n|sufficient binding region:356-600	maltose binding protein tag:?-?|sufficient binding region:448-631	-	-	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)	psi-mi:"MI:0818"(molecular weight estimation by coomasie staining)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0107"(surface plasmon resonance)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0407"(direct interaction)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996416|imex:IM-29015-51	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Fig. 6E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:-1(in vitro)|taxid:-1(In vitro)	-	2021/06/15	2021/06/16	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:uMD9Z8E3v70F/5WqeY1I3dZyhgQ	false	glutathione s tranferase tag:n-n|sufficient binding region:356-600	maltose binding protein tag:?-?|sufficient binding region:448-631	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:O60826	uniprotkb:Q641Q2	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996954|imex:IM-29015-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	-	-	-	figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rigid:hpn7Hyihd7FDO+QooCBfgxAHrjw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:O60826	uniprotkb:Q567U6	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996954|imex:IM-29015-15	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:hpn7Hyihd7FDO+QooCBfgxAHrjw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q641Q2	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996959|imex:IM-29015-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	-	-	-	figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rigid:hpn7Hyihd7FDO+QooCBfgxAHrjw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:O60826	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996959|imex:IM-29015-37	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Supp. Fig. 6B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:hpn7Hyihd7FDO+QooCBfgxAHrjw	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q96QK1	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1054634|uniprotkb:Q561W2|uniprotkb:Q9H016|uniprotkb:Q9H096|uniprotkb:Q9H4P3|uniprotkb:Q9H8J0|uniprotkb:Q9NRS7|uniprotkb:Q9NVG2|uniprotkb:Q9NX80|uniprotkb:Q9NZK2|ensembl:ENSP00000299138	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:vps35_human(display_long)|uniprotkb:Vesicle protein sorting 35(gene name synonym)|uniprotkb:Maternal-embryonic 3(gene name synonym)|uniprotkb:VPS35(gene name)|psi-mi:VPS35(display_short)|uniprotkb:MEM3(gene name synonym)|uniprotkb:TCCCTA00141(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996964|imex:IM-29015-73	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	refseq:NP_060676.2|rcsb pdb:5F0J|rcsb pdb:5F0K|rcsb pdb:5F0L|rcsb pdb:5F0M|rcsb pdb:5F0P|rcsb pdb:5OSH|rcsb pdb:5OSI|rcsb pdb:7BLN|rcsb pdb:7BLO|reactome:R-HSA-3238698|ensembl:ENSG00000069329(gene)|ensembl:ENST00000299138(transcript)|go:"GO:0005764"(lysosome)|go:"GO:0005765"(lysosomal membrane)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005770"(late endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010821"(regulation of mitochondrion organization)|go:"GO:0016055"(Wnt signaling pathway)|go:"GO:0016241"(regulation of macroautophagy)|go:"GO:0030904"(retromer complex)|go:"GO:0030906"(retromer, cargo-selective complex)|go:"GO:0031647"(regulation of protein stability)|go:"GO:0031748"(D1 dopamine receptor binding)|go:"GO:0032268"(regulation of cellular protein metabolic process)|go:"GO:0032456"(endocytic recycling)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043653"(mitochondrial fragmentation involved in apoptotic process)|go:"GO:0045056"(transcytosis)|go:"GO:0050728"(negative regulation of inflammatory response)|go:"GO:0060161"(positive regulation of dopamine receptor signaling pathway)|go:"GO:0060548"(negative regulation of cell death)|go:"GO:0070062"(extracellular exosome)|go:"GO:0090141"(positive regulation of mitochondrial fission)|go:"GO:0097422"(tubular endosome)|go:"GO:0099073"(mitochondrion-derived vesicle)|go:"GO:0099074"(mitochondrion to lysosome transport)|go:"GO:0099639"(neurotransmitter receptor transport, endosome to plasma membrane)|go:"GO:1901215"(negative regulation of neuron death)|go:"GO:1902823"(negative regulation of late endosome to lysosome transport)|go:"GO:1902950"(regulation of dendritic spine maintenance)|go:"GO:1903364"(positive regulation of cellular protein catabolic process)|go:"GO:1905606"(regulation of presynapse assembly)|go:"GO:2000331"(regulation of terminal button organization)|interpro:IPR005378(Vacuolar protein sorting-associated protein 35)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR042491|rcsb pdb:2R17|dip:DIP-29076N	-	-	-	figure legend:Supp. Figs. 6B, 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:EXkMduDQKNCdp876vGF5vna9t389606	rigid:jYx8g3ot9RQKdnsAAZuz3ew09Ns	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q7Z3J2	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996964|imex:IM-29015-73	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Supp. Figs. 6B, 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:jYx8g3ot9RQKdnsAAZuz3ew09Ns	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:O60826	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996964|imex:IM-29015-73	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Supp. Figs. 6B, 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:jYx8g3ot9RQKdnsAAZuz3ew09Ns	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26996964|imex:IM-29015-73	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Supp. Figs. 6B, 6C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:jYx8g3ot9RQKdnsAAZuz3ew09Ns	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q7Z3J2	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997015|imex:IM-29015-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Supp. Figs. 6C|comment:Interaction observed in VPS35 siRNA-treated cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:O60826	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997015|imex:IM-29015-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Supp. Figs. 6C|comment:Interaction observed in VPS35 siRNA-treated cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q641Q2	uniprotkb:Q567U6	intact:EBI-2870155|intact:EBI-4401456|uniprotkb:A2A3S2|uniprotkb:A2A3U6|uniprotkb:Q5SNT6|uniprotkb:Q6DHY0|intact:EBI-28969894|ensembl:ENSP00000282633	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:wac2a_human(display_long)|uniprotkb:WASHC2A(gene name)|psi-mi:WASHC2A(display_short)|uniprotkb:FAM21A(gene name synonym)|uniprotkb:FAM21B(gene name synonym)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997015|imex:IM-29015-75	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSP00000282633|ensembl:ENST00000351071|ensembl:ENSP00000344037|refseq:NP_001005751.1|refseq:NP_001278327.1|ensembl:ENSG00000099290(gene)|ensembl:ENST00000282633(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0008289"(lipid binding)|go:"GO:0015031"(protein transport)|go:"GO:0031901"(early endosome membrane)|go:"GO:0036010"(protein localization to endosome)|go:"GO:0042147"(retrograde transport, endosome to Golgi)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0071203"(WASH complex)|interpro:IPR029341|mint:Q641Q2|go:"GO:0005769"(early endosome)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Supp. Figs. 6C|comment:Interaction observed in VPS35 siRNA-treated cells.|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:JtzABQxJJmBcNqKPsm/t5KJa2Lw9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:Dn6sR9vv2TJMJ3JDZQ8yboPs18Q	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q7Z3J2	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997159|imex:IM-29015-85	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Supp. Fig. 6E|comment:Interaction observed in presence of WASHC2A siRNA|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:y9yH3SsSUJPcy5ZSJxIAYxrIQuA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:O60826	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997159|imex:IM-29015-85	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	-	-	-	figure legend:Supp. Fig. 6E|comment:Interaction observed in presence of WASHC2A siRNA|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rigid:y9yH3SsSUJPcy5ZSJxIAYxrIQuA	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JIG7	uniprotkb:Q8K4M5	intact:EBI-8311726|ensembl:ENSMUSP00000033483|intact:MINT-1865494|uniprotkb:Q8BYH4|uniprotkb:B1AVA1	intact:EBI-8589371|ensembl:ENSMUSP00000124719|uniprotkb:Q80WG2|uniprotkb:Q8BNL9|uniprotkb:Q80Z41|uniprotkb:Q8K2S9|intact:UNK-5521410|uniprotkb:Q3V012	psi-mi:ccd22_mouse(display_long)|uniprotkb:Ccdc22(gene name)|psi-mi:Ccdc22(display_short)|uniprotkb:DXImx40e(gene name synonym)	psi-mi:comd1_mouse(display_long)|uniprotkb:Commd1(gene name)|psi-mi:Commd1(display_short)|uniprotkb:Murr1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997047|imex:IM-29015-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031143(gene)|ensembl:ENSMUST00000033483(transcript)|go:"GO:0005768"(endosome)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:Q9JIG7|reactome:R-MMU-8951664|refseq:NP_613069.3	ensembl:ENSMUSG00000051355(gene)|ensembl:ENSMUST00000159081(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:1902072"(negative regulation of hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1905751"(positive regulation of endosome to plasma membrane protein transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8K4M5|reactome:R-MMU-8951664|refseq:NP_653097.2	-	comment:mint	function:Inhibits TNF-induced NFKB1 activation. May function to facilitate biliary copper excretion within hepatocytes|comment:mint	figure legend:Supp. Fig. 6D|comment:Interaction observed in Wash-deficient fibroblasts|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2021/06/15	2021/06/17	rogid:gmVzezOv+1Rb/3mGcUEltJJq8lA10090	rogid:EGVmsTepbqN4fOeK+cdAkLbDyuc10090	rigid:i8x3Kq5KdrnZQDbbUZGs2klCFM4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JIG7	uniprotkb:Q8BWQ6	intact:EBI-8311726|ensembl:ENSMUSP00000033483|intact:MINT-1865494|uniprotkb:Q8BYH4|uniprotkb:B1AVA1	intact:EBI-26997072|uniprotkb:Q3UWS3|uniprotkb:Q3UXM0|uniprotkb:Q7TQF5|uniprotkb:Q80XN3|uniprotkb:Q8R3A8|uniprotkb:Q91VY3|uniprotkb:Q9D307	psi-mi:ccd22_mouse(display_long)|uniprotkb:Ccdc22(gene name)|psi-mi:Ccdc22(display_short)|uniprotkb:DXImx40e(gene name synonym)	psi-mi:vp35l_mouse(display_long)|uniprotkb:Vps35l(gene name)|psi-mi:Vps35l(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997047|imex:IM-29015-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031143(gene)|ensembl:ENSMUST00000033483(transcript)|go:"GO:0005768"(endosome)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:Q9JIG7|reactome:R-MMU-8951664|refseq:NP_613069.3	refseq:NP_082091.3|reactome:R-MMU-6798695|interpro:IPR029705|go:"GO:0005768"(endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)	-	comment:mint	-	figure legend:Supp. Fig. 6D|comment:Interaction observed in Wash-deficient fibroblasts|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2021/06/15	2021/06/17	rogid:gmVzezOv+1Rb/3mGcUEltJJq8lA10090	rogid:Glr6H+jZ6efxcBhPC7INvmg6rwE10090	rigid:i8x3Kq5KdrnZQDbbUZGs2klCFM4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9JIG7	uniprotkb:Q7TQK5	intact:EBI-8311726|ensembl:ENSMUSP00000033483|intact:MINT-1865494|uniprotkb:Q8BYH4|uniprotkb:B1AVA1	intact:EBI-26997054|uniprotkb:Q3TX53|ensembl:ENSMUSP00000043442	psi-mi:ccd22_mouse(display_long)|uniprotkb:Ccdc22(gene name)|psi-mi:Ccdc22(display_short)|uniprotkb:DXImx40e(gene name synonym)	psi-mi:ccd93_mouse(display_long)|uniprotkb:Ccdc93(gene name)|psi-mi:Ccdc93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997047|imex:IM-29015-39	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSMUSG00000031143(gene)|ensembl:ENSMUST00000033483(transcript)|go:"GO:0005768"(endosome)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:Q9JIG7|reactome:R-MMU-8951664|refseq:NP_613069.3	refseq:NP_001020327.1|ensembl:ENSMUSG00000026339(gene)|ensembl:ENSMUST00000036025(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116	-	comment:mint	-	figure legend:Supp. Fig. 6D|comment:Interaction observed in Wash-deficient fibroblasts|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2021/06/15	2021/06/17	rogid:gmVzezOv+1Rb/3mGcUEltJJq8lA10090	rogid:voQArRPES/jO8Lq2Rvl5d+rY6Yk10090	rigid:i8x3Kq5KdrnZQDbbUZGs2klCFM4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BWQ6	uniprotkb:Q8K4M5	intact:EBI-26997072|uniprotkb:Q3UWS3|uniprotkb:Q3UXM0|uniprotkb:Q7TQF5|uniprotkb:Q80XN3|uniprotkb:Q8R3A8|uniprotkb:Q91VY3|uniprotkb:Q9D307	intact:EBI-8589371|ensembl:ENSMUSP00000124719|uniprotkb:Q80WG2|uniprotkb:Q8BNL9|uniprotkb:Q80Z41|uniprotkb:Q8K2S9|intact:UNK-5521410|uniprotkb:Q3V012	psi-mi:vp35l_mouse(display_long)|uniprotkb:Vps35l(gene name)|psi-mi:Vps35l(display_short)	psi-mi:comd1_mouse(display_long)|uniprotkb:Commd1(gene name)|psi-mi:Commd1(display_short)|uniprotkb:Murr1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997108|imex:IM-29015-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_082091.3|reactome:R-MMU-6798695|interpro:IPR029705|go:"GO:0005768"(endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)	ensembl:ENSMUSG00000051355(gene)|ensembl:ENSMUST00000159081(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0031648"(protein destabilization)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:1902072"(negative regulation of hypoxia-inducible factor-1alpha signaling pathway)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:1904109"(positive regulation of cholesterol import)|go:"GO:1905751"(positive regulation of endosome to plasma membrane protein transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|go:"GO:2000010"(positive regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8K4M5|reactome:R-MMU-8951664|refseq:NP_653097.2	-	-	function:Inhibits TNF-induced NFKB1 activation. May function to facilitate biliary copper excretion within hepatocytes|comment:mint	figure legend:Supp. Fig. 6D|comment:Interaction observed in Wash-deficient fibroblasts|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2021/06/15	2021/06/17	rogid:Glr6H+jZ6efxcBhPC7INvmg6rwE10090	rogid:EGVmsTepbqN4fOeK+cdAkLbDyuc10090	rigid:i8x3Kq5KdrnZQDbbUZGs2klCFM4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BWQ6	uniprotkb:Q9JIG7	intact:EBI-26997072|uniprotkb:Q3UWS3|uniprotkb:Q3UXM0|uniprotkb:Q7TQF5|uniprotkb:Q80XN3|uniprotkb:Q8R3A8|uniprotkb:Q91VY3|uniprotkb:Q9D307	intact:EBI-8311726|ensembl:ENSMUSP00000033483|intact:MINT-1865494|uniprotkb:Q8BYH4|uniprotkb:B1AVA1	psi-mi:vp35l_mouse(display_long)|uniprotkb:Vps35l(gene name)|psi-mi:Vps35l(display_short)	psi-mi:ccd22_mouse(display_long)|uniprotkb:Ccdc22(gene name)|psi-mi:Ccdc22(display_short)|uniprotkb:DXImx40e(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997108|imex:IM-29015-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_082091.3|reactome:R-MMU-6798695|interpro:IPR029705|go:"GO:0005768"(endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)	ensembl:ENSMUSG00000031143(gene)|ensembl:ENSMUST00000033483(transcript)|go:"GO:0005768"(endosome)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097006"(regulation of plasma lipoprotein particle levels)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:Q9JIG7|reactome:R-MMU-8951664|refseq:NP_613069.3	-	-	comment:mint	figure legend:Supp. Fig. 6D|comment:Interaction observed in Wash-deficient fibroblasts|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2021/06/15	2021/06/17	rogid:Glr6H+jZ6efxcBhPC7INvmg6rwE10090	rogid:gmVzezOv+1Rb/3mGcUEltJJq8lA10090	rigid:i8x3Kq5KdrnZQDbbUZGs2klCFM4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q8BWQ6	uniprotkb:Q7TQK5	intact:EBI-26997072|uniprotkb:Q3UWS3|uniprotkb:Q3UXM0|uniprotkb:Q7TQF5|uniprotkb:Q80XN3|uniprotkb:Q8R3A8|uniprotkb:Q91VY3|uniprotkb:Q9D307	intact:EBI-26997054|uniprotkb:Q3TX53|ensembl:ENSMUSP00000043442	psi-mi:vp35l_mouse(display_long)|uniprotkb:Vps35l(gene name)|psi-mi:Vps35l(display_short)	psi-mi:ccd93_mouse(display_long)|uniprotkb:Ccdc93(gene name)|psi-mi:Ccdc93(display_short)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:10090(mouse)|taxid:10090(Mus musculus)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0914"(association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997108|imex:IM-29015-17	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_082091.3|reactome:R-MMU-6798695|interpro:IPR029705|go:"GO:0005768"(endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)	refseq:NP_001020327.1|ensembl:ENSMUSG00000026339(gene)|ensembl:ENSMUST00000036025(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116	-	-	-	figure legend:Supp. Fig. 6D|comment:Interaction observed in Wash-deficient fibroblasts|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:10090(mouse-fibroblast)|taxid:10090(Mus musculus)	-	2021/06/15	2021/06/17	rogid:Glr6H+jZ6efxcBhPC7INvmg6rwE10090	rogid:voQArRPES/jO8Lq2Rvl5d+rY6Yk10090	rigid:i8x3Kq5KdrnZQDbbUZGs2klCFM4	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q567U6	uniprotkb:Q8N668	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997186|imex:IM-29015-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 7D|comment:Interaction observed in the absence of CCDC93|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:V71rw1YBLmfCiYzgxs7vnA/JRv0	false	fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:Q567U6	uniprotkb:Q7Z3J2	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	intact:EBI-11080070|uniprotkb:Q6PDA0|uniprotkb:Q69YI1|uniprotkb:Q7L371|uniprotkb:Q9H7C8|uniprotkb:Q9H0L7|uniprotkb:Q8WXA5|uniprotkb:A8K2M1|uniprotkb:Q86W66|uniprotkb:O43329|ensembl:ENSP00000395973	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:vp35l_human(display_long)|uniprotkb:VPS35L(gene name)|psi-mi:VPS35L(display_short)|uniprotkb:C16orf62(gene name synonym)|uniprotkb:Esophageal cancer-associated protein(gene name synonym)|uniprotkb:101F10.2(orf name)	psi-mi:"MI:0416"(fluorescence microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997186|imex:IM-29015-77	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	refseq:NP_064710.4|ensembl:ENSG00000103544(gene)|ensembl:ENST00000417362(transcript)|go:"GO:0005768"(endosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0016021"(integral component of membrane)|go:"GO:0032456"(endocytic recycling)|go:"GO:0101003"(ficolin-1-rich granule membrane)|interpro:IPR029705|mint:Q7Z3J2|reactome:R-HSA-6798695	-	-	-	figure legend:Supp. Fig. 7D|comment:Interaction observed in the absence of CCDC93|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rogid:Iu+BtohkwMt+eZRLnEJO+j0g7eY9606	rigid:V71rw1YBLmfCiYzgxs7vnA/JRv0	false	fluorescent protein tag:?-?	fluorescent protein tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:O60826	uniprotkb:Q567U6	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1104769|uniprotkb:Q4LE78|uniprotkb:Q53TJ2|uniprotkb:Q8TBX5|uniprotkb:Q9H6R5|uniprotkb:Q9NV15|uniprotkb:A8K3V7|ensembl:ENSP00000365477	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:ccd93_human(display_long)|uniprotkb:CCDC93(gene name)|psi-mi:CCDC93(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997287|imex:IM-29015-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	ensembl:ENSG00000125633(gene)|ensembl:ENST00000376300(transcript)|go:"GO:0005769"(early endosome)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043231"(intracellular membrane-bounded organelle)|interpro:IPR019159|interpro:IPR039116|mint:Q567U6|refseq:NP_061917.3	-	-	-	figure legend:Supp. Fig. 7D|comment:Interaction observed in the absence of CCDC93|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:YCq13XoQRo4g2UrgiKW48QFNY2Q9606	rigid:1AjuePNI2W9BXGJI5sWWA58ymME	false	fluorescent protein tag:?-?	fluorescent protein tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)
uniprotkb:O60826	uniprotkb:Q8N668	intact:EBI-3943153|uniprotkb:A8K7G1|ensembl:ENSP00000365401	intact:EBI-1550112|uniprotkb:Q96GS0|uniprotkb:B4DFQ4|ensembl:ENSP00000308236	psi-mi:ccd22_human(display_long)|uniprotkb:CCDC22(gene name)|psi-mi:CCDC22(display_short)|uniprotkb:CXorf37(gene name synonym)|uniprotkb:JM1(orf name)	psi-mi:comd1_human(display_long)|uniprotkb:COMMD1(gene name)|psi-mi:COMMD1(display_short)|uniprotkb:C2orf5(gene name synonym)|uniprotkb:MURR1(gene name synonym)|uniprotkb:Protein Murr1(gene name synonym)	psi-mi:"MI:0416"(fluorescence microscopy)	Phillips-Krawczak et al. (2015)	pubmed:25355947|imex:IM-29015	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26997287|imex:IM-29015-79	-	psi-mi:"MI:1060"(spoke expansion)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	ensembl:ENSG00000101997(gene)|ensembl:ENST00000376227(transcript)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0007253"(cytoplasmic sequestering of NF-kappaB)|go:"GO:0015031"(protein transport)|go:"GO:0032456"(endocytic recycling)|go:"GO:0043123"(positive regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043124"(negative regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0097602"(cullin family protein binding)|go:"GO:2000060"(positive regulation of ubiquitin-dependent protein catabolic process)|interpro:IPR008530(Protein of unknown function DUF812)|mint:O60826|reactome:R-HSA-8951664|refseq:NP_054727.1	refseq:NP_689729.1|ensembl:ENSG00000173163(gene)|ensembl:ENST00000311832(transcript)|go:"GO:0005507"(copper ion binding)|go:"GO:0005546"(phosphatidylinositol-4,5-bisphosphate binding)|go:"GO:0005547"(phosphatidylinositol-3,4,5-trisphosphate binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005768"(endosome)|go:"GO:0005769"(early endosome)|go:"GO:0005829"(cytosol)|go:"GO:0006289"(nucleotide-excision repair)|go:"GO:0006893"(Golgi to plasma membrane transport)|go:"GO:0010008"(endosome membrane)|go:"GO:0015031"(protein transport)|go:"GO:0019871"(sodium channel inhibitor activity)|go:"GO:0031398"(positive regulation of protein ubiquitination)|go:"GO:0031462"(Cul2-RING ubiquitin ligase complex)|go:"GO:0032088"(negative regulation of NF-kappaB transcription factor activity)|go:"GO:0032434"(regulation of proteasomal ubiquitin-dependent protein catabolic process)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043325"(phosphatidylinositol-3,4-bisphosphate binding)|go:"GO:0048227"(plasma membrane to endosome transport)|go:"GO:0055037"(recycling endosome)|go:"GO:0055070"(copper ion homeostasis)|go:"GO:0070300"(phosphatidic acid binding)|go:"GO:0080025"(phosphatidylinositol-3,5-bisphosphate binding)|go:"GO:1902306"(negative regulation of sodium ion transmembrane transport)|go:"GO:2000009"(negative regulation of protein localization to cell surface)|interpro:IPR017920|interpro:IPR033776|interpro:IPR037351|mint:Q8N668|rcsb pdb:2H2M|reactome:R-HSA-8951664	-	-	-	figure legend:Supp. Fig. 7D|comment:Interaction observed in the absence of CCDC93|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-hela)|taxid:9606(Homo sapiens epitheloid cervix carcinoma cells)	-	2021/06/15	2021/06/17	rogid:hG/dkzGeDmaMD8BuNCooTuwibMg9606	rogid:b4sVuz5jwndjw+8ejRFqOcLRk1I9606	rigid:1AjuePNI2W9BXGJI5sWWA58ymME	false	fluorescent protein tag:?-?	green fluorescent protein tag:?-?	-	-	psi-mi:"MI:1200"(immunocytochemistry)	psi-mi:"MI:1200"(immunocytochemistry)