#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P05154 uniprotkb:P21333-2 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-9641086|ensembl:ENSP00000353467 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:p21333-2(display_long)|uniprotkb:Actin-binding protein 280(gene name synonym)|uniprotkb:Alpha-filamin(gene name synonym)|uniprotkb:Endothelial actin-binding protein(gene name synonym)|uniprotkb:FLN(gene name synonym)|uniprotkb:FLN1(gene name synonym)|uniprotkb:Filamin-1(gene name synonym)|uniprotkb:Non-muscle filamin(gene name synonym)|uniprotkb:FLNA(gene name)|psi-mi:FLNA(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N intact:EBI-350432(isoform-parent)|ensembl:ENSG00000196924(gene)|ensembl:ENST00000360319(transcript)|uniprotkb:P21333-2(isoform-parent) - - isoform-comment:No experimental confirmation available. figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:r3XEZc6gmq37vSWBuSgyVvIf7Sc9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P26373 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-356849|uniprotkb:Q3KQT8|uniprotkb:Q9BPX0|uniprotkb:Q567Q8|uniprotkb:B4DLX3|uniprotkb:F5H1S2|ensembl:ENSP00000307889|ensembl:ENSP00000376811|ensembl:ENSP00000455009 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rl13_human(display_long)|uniprotkb:RPL13(gene name)|psi-mi:RPL13(display_short)|uniprotkb:BBC1(gene name synonym)|uniprotkb:Breast basic conserved protein 1(gene name synonym)|uniprotkb:Large ribosomal subunit protein eL13(gene name synonym)|uniprotkb:OK/SW-cl.46(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_000968.2|refseq:NP_150254.1|refseq:NP_001230059.1|refseq:NP_001230060.1|ensembl:ENSG00000167526(gene)|ensembl:ENST00000311528(transcript)|ensembl:ENST00000393099(transcript)|ensembl:ENST00000567815(transcript)|go:"GO:0001824"(blastocyst development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0060348"(bone development)|interpro:IPR001380(Ribosomal protein L13e)|interpro:IPR018256|mint:P26373|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-192823 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:2SZ+AEe41Ystwj9t9I0Z1cZ5GQ49606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P78330 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-1042956|uniprotkb:Q7Z3S5|uniprotkb:B2RCR5|ensembl:ENSP00000275605|ensembl:ENSP00000378854|ensembl:ENSP00000401639 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:serb_human(display_long)|uniprotkb:PSPH(gene name)|psi-mi:PSPH(display_short)|uniprotkb:O-phosphoserine phosphohydrolase(gene name synonym)|uniprotkb:L-3-phosphoserine phosphatase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N go:"GO:0009612"(response to mechanical stimulus)|go:"GO:0016311"(dephosphorylation)|go:"GO:0031667"(response to nutrient levels)|go:"GO:0033574"(response to testosterone)|go:"GO:0036424"(L-phosphoserine phosphatase activity)|go:"GO:0036425"(obsolete D-phosphoserine phosphatase activity)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043005"(neuron projection)|interpro:IPR004469(Phosphoserine phosphatase SerB)|interpro:IPR023214|interpro:IPR036412|rcsb pdb:1L8L|rcsb pdb:1L8O|rcsb pdb:1NNL|rcsb pdb:6HYJ|rcsb pdb:6HYY|rcsb pdb:6Q6J|reactome:R-HSA-977347|ensembl:ENSG00000146733(gene)|ensembl:ENST00000275605(transcript)|ensembl:ENST00000395471(transcript)|ensembl:ENST00000437355(transcript)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0004647"|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006563"(L-serine metabolic process)|go:"GO:0006564"(L-serine biosynthetic process)|refseq:XP_006715823.1|refseq:NP_004568.2|refseq:XP_011513763.1|refseq:XP_005271830.1|refseq:XP_005271831.1|refseq:XP_005271832.1|refseq:XP_005271833.1|refseq:XP_016867955.1|refseq:XP_016867956.1 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:gmgkmgyMOyxcEWV7n4hjn1NYEyA9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q92688-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-5279773|ensembl:ENSP00000345848 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:q92688-1(display_long)|uniprotkb:Anp32b1(isoform synonym)|uniprotkb:PHAPI2b(isoform synonym)|uniprotkb:ANP32B(gene name)|psi-mi:ANP32B(display_short)|uniprotkb:APRIL(gene name synonym)|uniprotkb:PHAPI2(gene name synonym)|uniprotkb:Acidic protein rich in leucines(gene name synonym)|uniprotkb:Putative HLA-DR-associated protein I-2(gene name synonym)|uniprotkb:Silver-stainable protein SSP29(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N intact:EBI-762428(isoform-parent)|ensembl:ENSG00000136938(gene)|ensembl:ENST00000339399(transcript) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:8eu0C8oHWUrZ28F2fIup9o5MDYk9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q15393-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-5455749|ensembl:ENSP00000305790 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:q15393-1(display_long)|uniprotkb:SF3B3(gene name)|psi-mi:SF3B3(display_short)|uniprotkb:KIAA0017(gene name synonym)|uniprotkb:SAP130(gene name synonym)|uniprotkb:Pre-mRNA-splicing factor SF3b 130 kDa subunit(gene name synonym)|uniprotkb:STAF130(gene name synonym)|uniprotkb:Spliceosome-associated protein 130(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N intact:EBI-346977(isoform-parent)|ensembl:ENSG00000189091(gene)|ensembl:ENST00000302516(transcript) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:gnCSXjZ/bwNXair6kyQUKoKIwbM9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q9P2J5 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-356077|uniprotkb:Q9NSE1|uniprotkb:A2RRR4|uniprotkb:B4DJ10|uniprotkb:Q2TU79|uniprotkb:A7E266|ensembl:ENSP00000377954 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:sylc_human(display_long)|uniprotkb:LARS1(gene name)|psi-mi:LARS1(display_short)|uniprotkb:KIAA1352(gene name synonym)|uniprotkb:LARS(gene name synonym)|uniprotkb:Leucyl-tRNA synthetase(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_064502.9|refseq:NP_001304893.1|refseq:NP_001304894.1|refseq:NP_057544.2|refseq:XP_011535958.1|ensembl:ENSG00000133706(gene)|ensembl:ENST00000394434(transcript)|go:"GO:0002161"(aminoacyl-tRNA editing activity)|go:"GO:0004819"(glutamine-tRNA ligase activity)|go:"GO:0004823"(leucine-tRNA ligase activity)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005764"(lysosome)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006425"(glutaminyl-tRNA aminoacylation)|go:"GO:0006429"(leucyl-tRNA aminoacylation)|go:"GO:0008361"(regulation of cell size)|go:"GO:0012505"(endomembrane system)|go:"GO:0016604"(nuclear body)|go:"GO:0017101"(aminoacyl-tRNA synthetase multienzyme complex)|go:"GO:0032008"(positive regulation of TOR signaling)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0043547"(positive regulation of GTPase activity)|go:"GO:0071230"(cellular response to amino acid stimulus)|go:"GO:0071233"(cellular response to leucine)|go:"GO:1904263"(positive regulation of TORC1 signaling)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR001412(Aminoacyl-tRNA synthetase, class I, conserved site)|interpro:IPR002300(Aminoacyl-tRNA synthetase, class Ia)|interpro:IPR004493(Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic)|interpro:IPR009008(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class Ia, editing)|interpro:IPR009080(Aminoacyl-tRNA synthetase, class 1a, anticodon-binding)|interpro:IPR013155(Valyl/Leucyl/Isoleucyl-tRNA synthetase, class I, anticodon-binding)|mint:Q9P2J5|rcsb pdb:2WFD|rcsb pdb:6KID|rcsb pdb:6KIE|rcsb pdb:6KQY|rcsb pdb:6KR7|rcsb pdb:6LPF|rcsb pdb:6LR6|reactome:R-HSA-2408522|reactome:R-HSA-379716 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:nlK4kRCik2LLC3VNl0sryrLLnqA9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P47756-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-353604|ensembl:ENSP00000364284|ensembl:ENSP00000501528 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:p47756-1(display_long)|uniprotkb:CAPZB(gene name)|psi-mi:CAPZB(display_short)|uniprotkb:CapZ beta(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N intact:EBI-353595(capzb_human)|ensembl:ENST00000375142(transcript)|ensembl:ENST00000674432(transcript)|ensembl:ENSG00000077549(gene) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:qRXsrB2fLT1DMVIVRWKFYe4Aln49606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:O60841 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-928530|uniprotkb:O95805|uniprotkb:Q9UF81|uniprotkb:Q9UMN7|uniprotkb:Q53RV7|uniprotkb:Q53SI8|ensembl:ENSP00000289371 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:if2p_human(display_long)|uniprotkb:EIF5B(gene name)|psi-mi:EIF5B(display_short)|uniprotkb:IF2(gene name synonym)|uniprotkb:KIAA0741(gene name synonym)|uniprotkb:Translation initiation factor IF-2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_056988.3|ensembl:ENSG00000158417(gene)|ensembl:ENST00000289371(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0046872"(metal ion binding)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR015760(Translation initiation factor 2 related)|interpro:IPR023115|interpro:IPR027417|interpro:IPR036925|mint:O60841|reactome:R-HSA-72706 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:5rLXO0ZcDcwLGOM4ZGA4fvQJ33U9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P07900-2 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-6190772|ensembl:ENSP00000335153 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:p07900-2(display_long)|uniprotkb:Lipopolysaccharide-associated protein 2(gene name synonym)|uniprotkb:HSP90AA1-2(isoform synonym)|uniprotkb:HSP90AA1(gene name)|psi-mi:HSP90AA1(display_short)|uniprotkb:HSP90A(gene name synonym)|uniprotkb:HSPC1(gene name synonym)|uniprotkb:HSPCA(gene name synonym)|uniprotkb:Heat shock 86 kDa(gene name synonym)|uniprotkb:Renal carcinoma antigen NY-REN-38(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N ensembl:ENSG00000080824(gene)|ensembl:ENST00000334701(transcript)|intact:EBI-296047(isoform-parent)|uniprotkb:P07900-2(isoform-parent) - - isoform-comment:"Variant in position: 71:M->L (in dbSNP:rs8005905)." figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:zSFsoTnWMCxMgg5CMgkY21uBpb89606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P62917 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-438527|ensembl:ENSP00000262584|ensembl:ENSP00000378378|ensembl:ENSP00000433464|uniprotkb:P25120|uniprotkb:Q567Q7|uniprotkb:Q969V7|uniprotkb:Q9BWQ9|uniprotkb:A8K094|uniprotkb:D3DWN2 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rl8_human(display_long)|uniprotkb:RPL8(gene name)|psi-mi:RPL8(display_short)|uniprotkb:Large ribosomal subunit protein uL2(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N rcsb pdb:4CCN|rcsb pdb:4CCO|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:4Y3O|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|ensembl:ENSG00000161016(gene)|ensembl:ENST00000262584(transcript)|ensembl:ENST00000394920(transcript)|ensembl:ENST00000528957(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0098794"(postsynapse)|interpro:IPR002171(Ribosomal protein L2)|interpro:IPR008991(Translation protein SH3-like)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR014722(Translation protein SH3-like, subgroup)|interpro:IPR014726(Ribosomal protein L2, domain 3)|interpro:IPR022666|interpro:IPR022669|interpro:IPR022671|interpro:IPR023672|mint:P62917|rcsb pdb:4CCM|refseq:NP_000964.1|refseq:NP_150644.1|refseq:NP_001304700.1|refseq:NP_001304711.1|dip:DIP-37967N - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:+b/ORzdCy/nqFLsKRV9VhIZgdjg9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P23396 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-351193|uniprotkb:Q498B5|uniprotkb:Q8NI95|uniprotkb:B2R7N5|ensembl:ENSP00000433821|ensembl:ENSP00000434643|ensembl:ENSP00000436971|uniprotkb:J3KN86 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rs3_human(display_long)|uniprotkb:RPS3(gene name)|psi-mi:RPS3(display_short)|uniprotkb:Small ribosomal subunit protein uS3(gene name synonym)|uniprotkb:OK/SW-cl.26(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_000996.2|ensembl:ENSG00000149273(gene)|ensembl:ENST00000524851(transcript)|ensembl:ENST00000527446(transcript)|ensembl:ENST00000531188(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003684"(damaged DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0003906"("DNA-(apurinic or apyrimidinic site) endonuclease activity")|go:"GO:0004520"(endodeoxyribonuclease activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005844"(polysome)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006281"(DNA repair)|go:"GO:0006412"(translation)|go:"GO:0006413"(translational initiation)|go:"GO:0006915"(apoptotic process)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0007059"(chromosome segregation)|go:"GO:0008017"(microtubule binding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014069"(postsynaptic density)|go:"GO:0015631"(tubulin binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019899"(enzyme binding)|go:"GO:0019900"(kinase binding)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030544"(Hsp70 protein binding)|go:"GO:0031116"(positive regulation of microtubule polymerization)|go:"GO:0031334"(positive regulation of protein-containing complex assembly)|go:"GO:0031397"(negative regulation of protein ubiquitination)|go:"GO:0032079"(positive regulation of endodeoxyribonuclease activity)|go:"GO:0032357"(oxidized purine DNA binding)|go:"GO:0032358"(oxidized pyrimidine DNA binding)|go:"GO:0032587"(ruffle membrane)|go:"GO:0032743"(positive regulation of interleukin-2 production)|go:"GO:0034614"(cellular response to reactive oxygen species)|go:"GO:0042104"(positive regulation of activated T cell proliferation)|go:"GO:0042769"(obsolete DNA damage response, detection of DNA damage)|go:"GO:0042981"(regulation of apoptotic process)|go:"GO:0043507"(positive regulation of JUN kinase activity)|go:"GO:0044390"(ubiquitin-like protein conjugating enzyme binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045738"(negative regulation of DNA repair)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0050862"(positive regulation of T cell receptor signaling pathway)|go:"GO:0051018"(protein kinase A binding)|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|go:"GO:0051225"(spindle assembly)|go:"GO:0051301"(cell division)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:0051536"(iron-sulfur cluster binding)|go:"GO:0051879"(Hsp90 protein binding)|go:"GO:0061481"(response to TNF agonist)|go:"GO:1902231"(positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage)|go:"GO:1902546"(positive regulation of DNA N-glycosylase activity)|go:"GO:1905053"(positive regulation of base-excision repair)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:2001235"(positive regulation of apoptotic signaling pathway)|go:"GO:2001272"(positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis)|go:"GO:0070062"(extracellular exosome)|interpro:IPR001351(Ribosomal protein S3, C-terminal)|go:"GO:0070181"(small ribosomal subunit rRNA binding)|interpro:IPR004044(K Homology, type 2)|go:"GO:0070301"(cellular response to hydrogen peroxide)|interpro:IPR005703(Ribosomal protein S3, eukaryotic/archaeal)|go:"GO:0071159"(NF-kappaB complex)|interpro:IPR009019(K Homology, prokaryotic type)|interpro:IPR015946(K homology-like, alpha/beta)|go:"GO:0071356"(cellular response to tumor necrosis factor)|interpro:IPR018280|interpro:IPR036419|mint:P23396|rcsb pdb:1WH9|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|go:"GO:0072686"(mitotic spindle)|go:"GO:0097100"(supercoiled DNA binding)|rcsb pdb:6QZP|go:"GO:0140078"("class I DNA-(apurinic or apyrimidinic site) endonuclease activity")|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBS|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOL|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|refseq:NP_001243731.1|refseq:NP_001247436.1|refseq:NP_001247435.1|dip:DIP-33177N - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:fsDW18AMR3YyEEIhMVcngYRWkps9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P30041 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-2255129|uniprotkb:A8JZY7|uniprotkb:P32077|uniprotkb:Q5TAH4|uniprotkb:Q5ZEZ8|ensembl:ENSP00000342026 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:prdx6_human(display_long)|uniprotkb:PRDX6(gene name)|psi-mi:PRDX6(display_short)|uniprotkb:AOP2(gene name synonym)|uniprotkb:KIAA0106(gene name synonym)|uniprotkb:Antioxidant protein 2(gene name synonym)|uniprotkb:1-Cys peroxiredoxin(gene name synonym)|uniprotkb:Acidic calcium-independent phospholipase A2(gene name synonym)|uniprotkb:Non-selenium glutathione peroxidase(gene name synonym)|uniprotkb:24 kDa protein(gene name synonym)|uniprotkb:Liver 2D page spot 40(gene name synonym)|uniprotkb:Red blood cells page spot 12(gene name synonym)|uniprotkb:Glutathione-dependent peroxiredoxin(gene name synonym)|uniprotkb:Lysophosphatidylcholine acyltransferase 5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_004896.1|ensembl:ENSG00000117592(gene)|ensembl:ENST00000340385(transcript)|go:"GO:0004602"(glutathione peroxidase activity)|go:"GO:0004623"(phospholipase A2 activity)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0016020"(membrane)|go:"GO:0031625"(ubiquitin protein ligase binding)|go:"GO:0035578"(azurophil granule lumen)|go:"GO:0042802"(identical protein binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0045454"(cell redox homeostasis)|go:"GO:0046475"(glycerophospholipid catabolic process)|go:"GO:0047184"(1-acylglycerophosphocholine O-acyltransferase activity)|go:"GO:0047499"(calcium-independent phospholipase A2 activity)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051920"(peroxiredoxin activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098869"(cellular oxidant detoxification)|go:"GO:0102567"|go:"GO:0102568"|interpro:IPR000866(Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen)|interpro:IPR013766(Thioredoxin domain)|interpro:IPR019479|interpro:IPR024706|interpro:IPR036249|rcsb pdb:1PRX|rcsb pdb:5B6M|rcsb pdb:5B6N|reactome:R-HSA-3299685|reactome:R-HSA-6798695|go:"GO:0042744"(hydrogen peroxide catabolic process) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:ZMsHgrAJf0VJiCELzo+zSi8Ji+49606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P62906 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-356860|uniprotkb:P52859|uniprotkb:P53025|uniprotkb:Q5TZT6|uniprotkb:Q8J013|uniprotkb:B2R801|ensembl:ENSP00000363018 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rl10a_human(display_long)|uniprotkb:RPL10A(gene name)|psi-mi:RPL10A(display_short)|uniprotkb:NEDD6(gene name synonym)|uniprotkb:CSA-19(gene name synonym)|uniprotkb:Neural precursor cell expressed developmentally down-regulated protein 6(gene name synonym)|uniprotkb:Large ribosomal subunit protein uL1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_009035.3|ensembl:ENSG00000198755(gene)|ensembl:ENST00000322203(transcript)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042788"(polysomal ribosome)|go:"GO:0045471"(response to ethanol)|go:"GO:0070062"(extracellular exosome)|interpro:IPR002143(Ribosomal protein L1)|interpro:IPR016095(Ribosomal protein L1, 3-layer alpha/beta-sandwich)|interpro:IPR023673|interpro:IPR023674|interpro:IPR028364|mint:P62906|rcsb pdb:4UG0|rcsb pdb:4V6X|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LU8|rcsb pdb:6OLG|rcsb pdb:6QZP|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72689|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:wrXKX6vzZ3ovXP3yUoL1/r+NGiw9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P49736 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-374819|uniprotkb:Q14577|uniprotkb:Q15023|uniprotkb:Q8N2V1|uniprotkb:Q969W7|uniprotkb:Q96AE1|uniprotkb:Q9BRM7|ensembl:ENSP00000265056 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:mcm2_human(display_long)|uniprotkb:MCM2(gene name)|psi-mi:MCM2(display_short)|uniprotkb:BM28(gene name synonym)|uniprotkb:CDCL1(gene name synonym)|uniprotkb:KIAA0030(gene name synonym)|uniprotkb:Minichromosome maintenance protein 2 homolog(gene name synonym)|uniprotkb:Nuclear protein BM28(gene name synonym)|uniprotkb:CCNL1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N ensembl:ENSG00000073111(gene)|ensembl:ENST00000265056(transcript)|go:"GO:0000727"(double-strand break repair via break-induced replication)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0003677"(DNA binding)|go:"GO:0003678"(DNA helicase activity)|go:"GO:0003688"(DNA replication origin binding)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005664"(nuclear origin of replication recognition complex)|go:"GO:0005737"(cytoplasm)|go:"GO:0006260"(DNA replication)|go:"GO:0006267"(pre-replicative complex assembly involved in nuclear cell cycle DNA replication)|go:"GO:0006268"(DNA unwinding involved in DNA replication)|go:"GO:0006270"(DNA replication initiation)|go:"GO:0006334"(nucleosome assembly)|go:"GO:0006915"(apoptotic process)|go:"GO:0019899"(enzyme binding)|go:"GO:0042393"(histone binding)|go:"GO:0042555"(MCM complex)|go:"GO:0046872"(metal ion binding)|go:"GO:0071162"(CMG complex)|go:"GO:0071353"(cellular response to interleukin-4)|go:"GO:0090102"(cochlea development)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902975"(mitotic DNA replication initiation)|go:"GO:1905775"(negative regulation of DNA helicase activity)|interpro:IPR001208(MCM)|interpro:IPR008045(MCM protein 2)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|interpro:IPR018525|interpro:IPR027417|interpro:IPR027925|interpro:IPR031327|interpro:IPR033762|interpro:IPR041562|mint:P49736|rcsb pdb:4UUZ|rcsb pdb:5BNV|rcsb pdb:5BNX|rcsb pdb:5BO0|rcsb pdb:5C3I|rcsb pdb:5JA4|rcsb pdb:6XTX|rcsb pdb:6XTY|rcsb pdb:6YA7|rcsb pdb:7CIZ|rcsb pdb:7CJ0|reactome:R-HSA-176187|reactome:R-HSA-176974|reactome:R-HSA-68867|reactome:R-HSA-68949|reactome:R-HSA-68962|reactome:R-HSA-69052|refseq:NP_004517.2|dip:DIP-31732N - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:Jt9ODNyJBwtwQ0pb/+X46vtHfE09606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q9HAV4 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-517949|uniprotkb:Q5JTE6|uniprotkb:Q96G48|uniprotkb:Q96HN3|uniprotkb:Q9BWM6|uniprotkb:Q9BZV5|uniprotkb:Q9H9M4|uniprotkb:Q9NT89|uniprotkb:Q9NW39|uniprotkb:Q9ULC9|ensembl:ENSP00000265351 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:xpo5_human(display_long)|uniprotkb:Ran-binding protein 21(gene name synonym)|uniprotkb:XPO5(gene name)|psi-mi:XPO5(display_short)|uniprotkb:KIAA1291(gene name synonym)|uniprotkb:RANBP21(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_065801.1|dip:DIP-34547N|rcsb pdb:5YU7|reactome:R-HSA-203927|ensembl:ENSG00000124571(gene)|ensembl:ENST00000265351(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0005049"(nuclear export signal receptor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006405"(RNA export from nucleus)|go:"GO:0006611"(protein export from nucleus)|go:"GO:0010586"(miRNA metabolic process)|go:"GO:0016442"(RISC complex)|go:"GO:0031267"(small GTPase binding)|go:"GO:0035281"(pre-miRNA export from nucleus)|go:"GO:0042565"(RNA nuclear export complex)|go:"GO:0070883"(pre-miRNA binding)|go:"GO:1900370"(positive regulation of RNA interference)|go:"GO:1905172"(RISC complex binding)|interpro:IPR001494(Importin-beta, N-terminal)|interpro:IPR011989(Armadillo-like helical)|interpro:IPR013598(Exportin-1/Importin-beta-like)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR040018|mint:Q9HAV4|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|rcsb pdb:3A6P|rcsb pdb:5YU6 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:wuUAxvyCl/u7CRtQLMK9McSoUrM9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q8N163-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-1021318|ensembl:ENSP00000310670|ensembl:ENSP00000373930 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:q8n163-1(display_long)|uniprotkb:CCAR2(gene name)|psi-mi:CCAR2(display_short)|uniprotkb:Cell division cycle and apoptosis regulator protein 2(gene name synonym)|uniprotkb:DBC1(gene name synonym)|uniprotkb:DBIRD complex subunit KIAA1967(gene name synonym)|uniprotkb:Deleted in breast cancer gene 1 protein(gene name synonym)|uniprotkb:KIAA1967(gene name synonym)|uniprotkb:p30 DBC(gene name synonym)|uniprotkb:NET35(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N intact:EBI-355410(q8n163_human)|ensembl:ENSG00000158941(gene)|ensembl:ENST00000308511(transcript)|ensembl:ENST00000389279(transcript) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:GL+fD8W0kadrYrBkuMqoKgbbITU9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P04792 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-352682|uniprotkb:Q6FI47|uniprotkb:Q96C20|uniprotkb:Q96EI7|uniprotkb:Q9UC34|uniprotkb:Q9UC35|uniprotkb:Q9UC36|uniprotkb:Q9UC31|ensembl:ENSP00000248553|uniprotkb:B2R4N8 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:hspb1_human(display_long)|uniprotkb:HSPB1(gene name)|psi-mi:HSPB1(display_short)|uniprotkb:HSP27(gene name synonym)|uniprotkb:HSP28(gene name synonym)|uniprotkb:Heat shock 27 kDa protein(gene name synonym)|uniprotkb:Stress-responsive protein 27(gene name synonym)|uniprotkb:Estrogen-regulated 24 kDa protein(gene name synonym)|uniprotkb:28 kDa heat shock protein(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_001531.1|ensembl:ENSG00000106211(gene)|ensembl:ENST00000248553(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0001895"(retina homeostasis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0003723"(RNA binding)|go:"GO:0005080"(protein kinase C binding)|go:"GO:0005615"(extracellular space)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005819"(spindle)|go:"GO:0005829"(cytosol)|go:"GO:0005856"(cytoskeleton)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006469"(negative regulation of protein kinase activity)|go:"GO:0006986"(response to unfolded protein)|go:"GO:0008426"(protein kinase C inhibitor activity)|go:"GO:0009615"(response to virus)|go:"GO:0010506"(regulation of autophagy)|go:"GO:0019901"(protein kinase binding)|go:"GO:0030018"(Z disc)|go:"GO:0032731"(positive regulation of interleukin-1 beta production)|go:"GO:0032760"(positive regulation of tumor necrosis factor production)|go:"GO:0035556"(intracellular signal transduction)|go:"GO:0035924"(cellular response to vascular endothelial growth factor stimulus)|go:"GO:0038033"(positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway)|go:"GO:0042802"(identical protein binding)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0043122"(regulation of I-kappaB kinase/NF-kappaB signaling)|go:"GO:0043130"(ubiquitin binding)|go:"GO:0043536"(positive regulation of blood vessel endothelial cell migration)|go:"GO:0044183"(protein folding chaperone)|go:"GO:0045766"(positive regulation of angiogenesis)|go:"GO:0061077"(chaperone-mediated protein folding)|go:"GO:0061629"(RNA polymerase II-specific DNA-binding transcription factor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0099641"(anterograde axonal protein transport)|go:"GO:1902176"(negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2001028"(positive regulation of endothelial cell chemotaxis)|interpro:IPR001436(Alpha crystallin/Heat shock protein)|interpro:IPR002068(Heat shock protein Hsp20)|interpro:IPR008978(HSP20-like chaperone)|interpro:IPR037876|mint:P04792|rcsb pdb:2N3J|rcsb pdb:3Q9P|rcsb pdb:3Q9Q|rcsb pdb:4MJH|rcsb pdb:6DV5|rcsb pdb:6GJH|reactome:R-HSA-4420097|reactome:R-HSA-450408|reactome:R-HSA-5687128|reactome:R-HSA-9009391|dip:DIP-412N - - crc64:1B4DC44A6F6606D5 figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:vrDXIdzP30aHSDLHOh2D4x54eJY9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:O00299 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-347404|uniprotkb:Q15089|uniprotkb:Q502X1|ensembl:ENSP00000404037|ensembl:ENSP00000404589|ensembl:ENSP00000406088|ensembl:ENSP00000406335|ensembl:ENSP00000406968|ensembl:ENSP00000407429|ensembl:ENSP00000407791|ensembl:ENSP00000408094|ensembl:ENSP00000408357|ensembl:ENSP00000409247|ensembl:ENSP00000409979|ensembl:ENSP00000410965|ensembl:ENSP00000412217|ensembl:ENSP00000413330|ensembl:ENSP00000416211|ensembl:ENSP00000477623|ensembl:ENSP00000478930|ensembl:ENSP00000479501|ensembl:ENSP00000479808|ensembl:ENSP00000480256|ensembl:ENSP00000482255|ensembl:ENSP00000484581|ensembl:ENSP00000364934|ensembl:ENSP00000364935|ensembl:ENSP00000364940|ensembl:ENSP00000372896|ensembl:ENSP00000372897|ensembl:ENSP00000379229|ensembl:ENSP00000382926|ensembl:ENSP00000382931|ensembl:ENSP00000391395|ensembl:ENSP00000398056|ensembl:ENSP00000400280|ensembl:ENSP00000400532|ensembl:ENSP00000401292 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:clic1_human(display_long)|uniprotkb:CLIC1(gene name)|psi-mi:CLIC1(display_short)|uniprotkb:NCC27(gene name synonym)|uniprotkb:Nuclear chloride ion channel 27(gene name synonym)|uniprotkb:Chloride channel ABP(gene name synonym)|uniprotkb:Regulatory nuclear chloride ion channel protein(gene name synonym)|uniprotkb:G6(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_001279.2|refseq:NP_001274522.1|refseq:NP_001274523.1|ensembl:ENST00000375779(transcript)|ensembl:ENST00000375780(transcript)|ensembl:ENST00000375784(transcript)|ensembl:ENST00000383404(transcript)|ensembl:ENST00000383405(transcript)|ensembl:ENST00000395892(transcript)|go:"GO:0005635"(nuclear envelope)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005886"(plasma membrane)|go:"GO:0005903"(brush border)|go:"GO:0006749"(glutathione metabolic process)|go:"GO:0006821"(chloride transport)|go:"GO:0007165"(signal transduction)|go:"GO:0016020"(membrane)|go:"GO:0031965"(nuclear membrane)|go:"GO:0031982"(vesicle)|go:"GO:0034707"(chloride channel complex)|go:"GO:0034765"(regulation of ion transmembrane transport)|go:"GO:0045296"(cadherin binding)|go:"GO:0045669"(positive regulation of osteoblast differentiation)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0051726"(regulation of cell cycle)|go:"GO:0051881"(regulation of mitochondrial membrane potential)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070527"(platelet aggregation)|go:"GO:0072562"(blood microparticle)|interpro:IPR002946(Intracellular chloride channel)|interpro:IPR004045(Glutathione S-transferase, N-terminal)|interpro:IPR010987(Glutathione S-transferase, C-terminal-like)|interpro:IPR030259|go:"GO:0005634"(nucleus)|ensembl:ENSG00000206394(gene)|ensembl:ENSG00000213719(gene)|ensembl:ENSG00000223639(gene)|ensembl:ENSG00000226248(gene)|ensembl:ENSG00000226417(gene)|ensembl:ENSG00000226651(gene)|ensembl:ENSG00000230685(gene)|ensembl:ENST00000400052(transcript)|ensembl:ENST00000400058(transcript)|ensembl:ENST00000415179(transcript)|ensembl:ENST00000418285(transcript)|ensembl:ENST00000420458(transcript)|ensembl:ENST00000422167(transcript)|ensembl:ENST00000423055(transcript)|ensembl:ENST00000423143(transcript)|ensembl:ENST00000423804(transcript)|ensembl:ENST00000425464(transcript)|ensembl:ENST00000431921(transcript)|ensembl:ENST00000433916(transcript)|ensembl:ENST00000434202(transcript)|ensembl:ENST00000435242(transcript)|ensembl:ENST00000438708(transcript)|ensembl:ENST00000438750(transcript)|ensembl:ENST00000442045(transcript)|ensembl:ENST00000447338(transcript)|ensembl:ENST00000447369(transcript)|ensembl:ENST00000451546(transcript)|ensembl:ENST00000456863(transcript)|ensembl:ENST00000457485(transcript)|ensembl:ENST00000614673(transcript)|ensembl:ENST00000614982(transcript)|ensembl:ENST00000616760(transcript)|ensembl:ENST00000618288(transcript)|ensembl:ENST00000619727(transcript)|ensembl:ENST00000621055(transcript)|ensembl:ENST00000622613(transcript)|go:"GO:0005244"(voltage-gated ion channel activity)|go:"GO:0005254"(chloride channel activity)|go:"GO:0005615"(extracellular space)|interpro:IPR036282|interpro:IPR040079|mint:O00299|interpro:IPR036249|rcsb pdb:1K0M|rcsb pdb:1K0N|rcsb pdb:1K0O|rcsb pdb:1RK4|rcsb pdb:3O3T|rcsb pdb:3P8W|rcsb pdb:3P90|rcsb pdb:3QR6|rcsb pdb:3SWL|rcsb pdb:3TGZ|rcsb pdb:3UVH|rcsb pdb:4IQA|rcsb pdb:4JZQ|rcsb pdb:4K0G|rcsb pdb:4K0N - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:HVux62IcNdqcPgqmlGlIyZTLpFo9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q00610-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-26968345|ensembl:ENSP00000269122 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:q00610-1(display_long)|uniprotkb:CLTC(gene name)|psi-mi:CLTC(display_short)|uniprotkb:CLH17(gene name synonym)|uniprotkb:CLTCL2(gene name synonym)|uniprotkb:KIAA0034(gene name synonym)|uniprotkb:Clathrin heavy chain on chromosome 17(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N ensembl:ENSG00000141367(gene)|ensembl:ENST00000269122(transcript)|intact:EBI-354967(isoform-parent) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:oGsLXL5J5MHO+ronpDIG9hJ11sU9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P62241 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-351811|uniprotkb:Q6IRL7|uniprotkb:P09058|ensembl:ENSP00000379888 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rs8_human(display_long)|uniprotkb:RPS8(gene name)|psi-mi:RPS8(display_short)|uniprotkb:Small ribosomal subunit protein eS8(gene name synonym)|uniprotkb:OK/SW-cl.83(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_001003.1|ensembl:ENSG00000142937(gene)|ensembl:ENST00000396651(transcript)|go:"GO:0000462"("maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001047(Ribosomal protein S8e)|interpro:IPR018283|interpro:IPR022309|interpro:IPR042563|mint:P62241|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:6G5H|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975957|reactome:R-HSA-975956 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:3rpCBdQyRWR+TCKnupbnCp30jKE9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q15149-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-27038408|ensembl:ENSP00000323856 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:q15149-1(display_long)|uniprotkb:Hemidesmosomal protein 1(gene name synonym)|uniprotkb:Plectin-1(gene name synonym)|uniprotkb:Plectin-6(isoform synonym)|uniprotkb:PLEC(gene name)|psi-mi:PLEC(display_short)|uniprotkb:PLEC1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N ensembl:ENSG00000178209(gene)|ensembl:ENST00000322810(transcript)|intact:EBI-297903(isoform-parent) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:zbctDAOOCaJUx3WBdp85v7SI0sI9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P56537 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-372243|uniprotkb:Q6IBN8|uniprotkb:Q96TD5|uniprotkb:B7ZBG9|ensembl:ENSP00000363559|ensembl:ENSP00000363574|ensembl:ENSP00000502429 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:if6_human(display_long)|uniprotkb:EIF6(gene name)|psi-mi:EIF6(display_short)|uniprotkb:ITGB4BP(gene name synonym)|uniprotkb:OK/SW-cl.27(orf name)|uniprotkb:B4 integrin interactor(gene name synonym)|uniprotkb:CAB(gene name synonym)|uniprotkb:"p27(BBP)"(gene name synonym)|uniprotkb:"B(2)GCN homolog"(gene name synonym)|uniprotkb:EIF3A(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_002203.1|refseq:NP_852131.1|refseq:NP_852133.1|refseq:NP_001254739.1|ensembl:ENSG00000242372(gene)|ensembl:ENST00000374436(transcript)|ensembl:ENST00000374450(transcript)|ensembl:ENST00000675032(transcript)|go:"GO:0000054"(ribosomal subunit export from nucleus)|go:"GO:0000460"(maturation of 5.8S rRNA)|go:"GO:0000470"(maturation of LSU-rRNA)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005638"(lamin filament)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0006110"(regulation of glycolytic process)|go:"GO:0030687"(preribosome, large subunit precursor)|go:"GO:0032868"(response to insulin)|go:"GO:0035195"(gene silencing by miRNA)|go:"GO:0035278"(miRNA-mediated gene silencing by inhibition of translation)|go:"GO:0042256"(mature ribosome assembly)|go:"GO:0042304"(regulation of fatty acid biosynthetic process)|go:"GO:0043022"(ribosome binding)|go:"GO:0043023"(ribosomal large subunit binding)|go:"GO:0045652"(regulation of megakaryocyte differentiation)|go:"GO:0045727"(positive regulation of translation)|go:"GO:0070062"(extracellular exosome)|go:"GO:1902626"(assembly of large subunit precursor of preribosome)|go:"GO:2000377"(regulation of reactive oxygen species metabolic process)|interpro:IPR002769(Translation initiation factor IF6)|mint:P56537|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:A0pOylQptNBlSiBKiZre7INejF49606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:Q92900-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-27038432|ensembl:ENSP00000470142 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:q92900-1(display_long)|uniprotkb:ATP-dependent helicase RENT1(gene name synonym)|uniprotkb:Nonsense mRNA reducing factor 1(gene name synonym)|uniprotkb:Up-frameshift suppressor 1 homolog(gene name synonym)|uniprotkb:UPF1(gene name)|psi-mi:UPF1(display_short)|uniprotkb:KIAA0221(gene name synonym)|uniprotkb:RENT1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N intact:EBI-373471(isoform-parent)|ensembl:ENSG00000005007(gene)|ensembl:ENST00000599848(transcript) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:ORqXFPAa7qA8cwM5qcNodIF0q/s9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P62753 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-356625|uniprotkb:P08227|uniprotkb:P10660|uniprotkb:Q4VBY7|uniprotkb:Q8N6Z7|ensembl:ENSP00000369757 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rs6_human(display_long)|uniprotkb:RPS6(gene name)|psi-mi:RPS6(display_short)|uniprotkb:Phosphoprotein NP33(gene name synonym)|uniprotkb:Small ribosomal subunit protein eS6(gene name synonym)|uniprotkb:OK/SW-cl.2(orf name) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_001001.2|reactome:R-HSA-166208|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|interpro:IPR014401(Ribosomal protein S6, eukaryotic)|interpro:IPR018282|mint:P62753|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6F4P|rcsb pdb:6F4Q|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|ensembl:ENSG00000137154(gene)|ensembl:ENST00000380394(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0001890"(placenta development)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0002309"(T cell proliferation involved in immune response)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0006924"(activation-induced cell death of T cells)|go:"GO:0007369"(gastrulation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019901"(protein kinase binding)|go:"GO:0022605"(mammalian oogenesis stage)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0030425"(dendrite)|go:"GO:0031929"(TOR signaling)|go:"GO:0033077"(T cell differentiation in thymus)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042274"(ribosomal small subunit biogenesis)|go:"GO:0042593"(glucose homeostasis)|go:"GO:0043065"(positive regulation of apoptotic process)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0044297"(cell body)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0048821"(erythrocyte development)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR001377(Ribosomal protein S6e)|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|dip:DIP-31507N - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:beDuXCIqL99V9JlVfpzx7MdpH689606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P18124 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-350806|uniprotkb:Q3KQU0|uniprotkb:Q15289|uniprotkb:Q5I0X1|uniprotkb:Q6IBM9|uniprotkb:A8K504|ensembl:ENSP00000339795 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rl7_human(display_long)|uniprotkb:RPL7(gene name)|psi-mi:RPL7(display_short)|uniprotkb:Large ribosomal subunit protein uL30(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_000962.2|ensembl:ENSG00000147604(gene)|ensembl:ENST00000352983(transcript)|go:"GO:0000463"("maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)")|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003677"(DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006364"(rRNA processing)|go:"GO:0006412"(translation)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016020"(membrane)|go:"GO:0022625"(cytosolic large ribosomal subunit)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0042273"(ribosomal large subunit biogenesis)|go:"GO:0042802"(identical protein binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR005998(Ribosomal protein L7, eukaryotic)|interpro:IPR012988(Ribosomal protein L30, N-terminal)|interpro:IPR016082(Ribosomal protein L30, C-terminal)|interpro:IPR018038|interpro:IPR035808|interpro:IPR036919|interpro:IPR039699|mint:P18124|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5AJ0|rcsb pdb:5LKS|rcsb pdb:5T2C|rcsb pdb:6EK0|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6LQM|rcsb pdb:6LSR|rcsb pdb:6LSS|rcsb pdb:6LU8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6W6L|rcsb pdb:6XA1|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6Y6X|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:7BHP|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6791226|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|reactome:R-HSA-72689 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:miVEaLOilDYcZXshxJlYbpnzwZ89606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P15880 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-443446|ensembl:ENSP00000341885|uniprotkb:Q3MIB1|uniprotkb:B2R5G0|uniprotkb:D3DU82 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:rs2_human(display_long)|uniprotkb:RPS2(gene name)|psi-mi:RPS2(display_short)|uniprotkb:RPS4(gene name synonym)|uniprotkb:40S ribosomal protein S4(gene name synonym)|uniprotkb:Protein LLRep3(gene name synonym)|uniprotkb:Small ribosomal subunit protein uS5(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N interpro:IPR014721(Ribosomal protein S5 domain 2-type fold)|rcsb pdb:6OLG|rcsb pdb:6OLI|interpro:IPR018192|rcsb pdb:6OLZ|interpro:IPR020568|mint:P15880|rcsb pdb:4UG0|rcsb pdb:6OM0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6EK0|rcsb pdb:6G18|rcsb pdb:6XA1|rcsb pdb:6G4S|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6Y0G|rcsb pdb:6Y2L|rcsb pdb:6G5H|rcsb pdb:6Y57|rcsb pdb:6YBD|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6Z6M|rcsb pdb:6Z6N|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7JQB|rcsb pdb:7JQC|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-3214858|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-8876725|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957|rcsb pdb:7A09|ensembl:ENSG00000140988(gene)|ensembl:ENST00000343262(transcript)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0016020"(membrane)|go:"GO:0017134"(fibroblast growth factor binding)|go:"GO:0019899"(enzyme binding)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045296"(cadherin binding)|go:"GO:0051443"(positive regulation of ubiquitin-protein transferase activity)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000851(Ribosomal protein S5)|interpro:IPR005324(Ribosomal protein S5, C-terminal)|interpro:IPR005711(Ribosomal protein S5, eukaryotic/archaeal)|interpro:IPR013810(Ribosomal protein S5, N-terminal)|refseq:NP_002943.2 - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:JUr2Y3cGk00S8KaTVPymshfaHhc9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:B4DTH2 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-27038420 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:b4dth2_human(display_long) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N go:"GO:0005576"(extracellular region)|go:"GO:0006953"(acute-phase response)|go:"GO:0007155"(cell adhesion)|go:"GO:0008201"(heparin binding)|go:"GO:0008360"(regulation of cell shape)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR036116|interpro:IPR013783(Immunoglobulin-like fold) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:7TW8o9qKmf/0vNohqwNEUuQPFGQ9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P02751-1 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-22099195|ensembl:ENSP00000352696 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:p02751-1(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:Cold-insoluble globulin(gene name synonym)|uniprotkb:FN(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N intact:EBI-1220319(isoform-parent)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000359671(transcript) - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:mrg1VDkvoOn5kbtGtkLOeYhRHqE9606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P04114 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-3926040|uniprotkb:Q9UMN0|uniprotkb:P78479|uniprotkb:P78480|uniprotkb:Q7Z600|uniprotkb:Q13786|uniprotkb:O00502|uniprotkb:P78481|uniprotkb:Q4ZG63|uniprotkb:Q13779|uniprotkb:Q13788|uniprotkb:Q13785|uniprotkb:Q13787|uniprotkb:Q53QC8|ensembl:ENSP00000233242 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:apob_human(display_long)|uniprotkb:APOB(gene name)|psi-mi:APOB(display_short) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0471"(MINT) intact:EBI-27038496|imex:IM-29099-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_000375.2|ensembl:ENSG00000084674(gene)|ensembl:ENST00000233242(transcript)|go:"GO:0001701"(in utero embryonic development)|go:"GO:0005543"(phospholipid binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005769"(early endosome)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005790"(smooth endoplasmic reticulum)|go:"GO:0005811"(lipid droplet)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006642"(triglyceride mobilization)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007399"(nervous system development)|go:"GO:0008201"(heparin binding)|go:"GO:0008203"(cholesterol metabolic process)|go:"GO:0009566"(fertilization)|go:"GO:0009615"(response to virus)|go:"GO:0009743"(response to carbohydrate)|go:"GO:0009791"(post-embryonic development)|go:"GO:0010008"(endosome membrane)|go:"GO:0010269"(response to selenium ion)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010744"(positive regulation of macrophage derived foam cell differentiation)|go:"GO:0010884"(positive regulation of lipid storage)|go:"GO:0010886"(positive regulation of cholesterol storage)|go:"GO:0019433"(triglyceride catabolic process)|go:"GO:0030301"(cholesterol transport)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0030669"(clathrin-coated endocytic vesicle membrane)|go:"GO:0031904"(endosome lumen)|go:"GO:0031983"(vesicle lumen)|go:"GO:0032355"(response to estradiol)|go:"GO:0032496"(response to lipopolysaccharide)|go:"GO:0033344"(cholesterol efflux)|go:"GO:0034359"(mature chylomicron)|go:"GO:0034360"(chylomicron remnant)|go:"GO:0034361"(very-low-density lipoprotein particle)|go:"GO:0034362"(low-density lipoprotein particle)|go:"GO:0034363"(intermediate-density lipoprotein particle)|go:"GO:0034364"(high-density lipoprotein particle)|go:"GO:0034374"(low-density lipoprotein particle remodeling)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:0034383"(low-density lipoprotein particle clearance)|go:"GO:0035473"(lipase binding)|go:"GO:0042158"(lipoprotein biosynthetic process)|go:"GO:0042159"(lipoprotein catabolic process)|go:"GO:0042627"(chylomicron)|go:"GO:0042632"(cholesterol homeostasis)|go:"GO:0042953"(lipoprotein transport)|go:"GO:0043025"(neuronal cell body)|go:"GO:0043202"(lysosomal lumen)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045540"(regulation of cholesterol biosynthetic process)|go:"GO:0048844"(artery morphogenesis)|go:"GO:0050750"(low-density lipoprotein particle receptor binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070971"(endoplasmic reticulum exit site)|go:"GO:0071356"(cellular response to tumor necrosis factor)|go:"GO:0071379"(cellular response to prostaglandin stimulus)|go:"GO:0071682"(endocytic vesicle lumen)|go:"GO:0120020"(cholesterol transfer activity)|interpro:IPR001747(Lipid transport protein, N-terminal)|interpro:IPR009454(Lipid transport, open beta-sheet)|interpro:IPR011030(Vitellinogen, superhelical)|interpro:IPR015255(Vitellinogen, open beta-sheet)|interpro:IPR015816(Vitellinogen, beta-sheet N-terminal)|interpro:IPR015819(Lipid transport protein, beta-sheet shell)|interpro:IPR016024(Armadillo-type fold)|interpro:IPR022176|mint:P04114|reactome:R-HSA-202733|reactome:R-HSA-3000471|reactome:R-HSA-3000480|reactome:R-HSA-3000484|reactome:R-HSA-3000497|reactome:R-HSA-381426|reactome:R-HSA-432142|reactome:R-HSA-8856825|reactome:R-HSA-8856828|reactome:R-HSA-8866423|reactome:R-HSA-8957275|reactome:R-HSA-8963888|reactome:R-HSA-8963901|reactome:R-HSA-8964026|reactome:R-HSA-8964038|reactome:R-HSA-8964041|reactome:R-HSA-5686938|reactome:R-HSA-8964046|reactome:R-HSA-9707616|reactome:R-HSA-975634|dip:DIP-44767N - - - figure legend:table s2 fig 6a|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hcclm-3)|taxid:9606(HCCLM-3 cell) - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:2A4FraaZg1hHoxDkvi6DsKpoCD49606 rigid:sgujGo0jDT8/9NEIJESJY9oyGyw false - - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:P05154 uniprotkb:P02751 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-27038537|imex:IM-29099-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:fig. 6b|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 rigid:nlsReRmYLwqzbXhRwzXygGeSwak false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05154 uniprotkb:P02751 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0471"(MINT) intact:EBI-27038541|imex:IM-29099-5 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:fig. 6b sf4|comment:"We identified an interaction between SERPINA5 and fibronectin in whole cell lysate (Figure 6B) but not in conditioned medium, which may be caused by the domain modification caused by glycosylation (Figure S4)."|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-hep_g2)|taxid:9606("Homo sapiens hepatocellular carcinoma (HCC) cells (p53-wt).") - 2021/07/19 2021/07/19 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 rigid:nlsReRmYLwqzbXhRwzXygGeSwak false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:P05154 uniprotkb:P02751 intact:EBI-722597|uniprotkb:Q07616|uniprotkb:Q9UG30|ensembl:ENSP00000333203|ensembl:ENSP00000450837|ensembl:ENSP00000451126|ensembl:ENSP00000451610 intact:EBI-1220319|uniprotkb:Q7Z391|uniprotkb:O95609|uniprotkb:O95610|uniprotkb:Q14312|uniprotkb:Q14325|uniprotkb:Q14326|uniprotkb:Q17RV7|uniprotkb:Q585T2|uniprotkb:Q59EH1|uniprotkb:Q60FE4|uniprotkb:Q68DP8|uniprotkb:Q68DP9|uniprotkb:Q68DT4|uniprotkb:Q6LDP6|uniprotkb:Q6MZU5|uniprotkb:Q6N025|uniprotkb:Q6N0A6|uniprotkb:Q86T27|uniprotkb:Q8IVI8|uniprotkb:Q96KP7|uniprotkb:Q96KP8|uniprotkb:Q96KP9|uniprotkb:Q9H1B8|uniprotkb:Q9HAP3|uniprotkb:Q9UMK2|uniprotkb:Q6MZS0|uniprotkb:B7ZLF0|uniprotkb:E9PE77|uniprotkb:E9PG29|uniprotkb:Q564H7|uniprotkb:Q53S27|ensembl:ENSP00000346839 psi-mi:ipsp_human(display_long)|uniprotkb:Serpin A5(gene name synonym)|uniprotkb:Protein C inhibitor(gene name synonym)|uniprotkb:Plasminogen activator inhibitor 3(gene name synonym)|uniprotkb:Acrosomal serine protease inhibitor(gene name synonym)|uniprotkb:SERPINA5(gene name)|psi-mi:SERPINA5(display_short)|uniprotkb:PCI(gene name synonym)|uniprotkb:PLANH3(gene name synonym)|uniprotkb:PROCI(gene name synonym) psi-mi:finc_human(display_long)|uniprotkb:FN1(gene name)|psi-mi:FN1(display_short)|uniprotkb:FN(gene name synonym)|uniprotkb:Cold-insoluble globulin(gene name synonym) psi-mi:"MI:0096"(pull down) Jing et al. (2014) imex:IM-29099|pubmed:24388360 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0407"(direct interaction) psi-mi:"MI:0471"(MINT) intact:EBI-27038558|imex:IM-29099-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_000615.3|ensembl:ENSG00000188488(gene)|ensembl:ENST00000329597(transcript)|ensembl:ENST00000553780(transcript)|ensembl:ENST00000554276(transcript)|ensembl:ENST00000554866(transcript)|go:"GO:0001972"(retinoic acid binding)|go:"GO:0002020"(protease binding)|go:"GO:0002080"(acrosomal membrane)|go:"GO:0004867"(serine-type endopeptidase inhibitor activity)|go:"GO:0005539"(glycosaminoglycan binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005615"(extracellular space)|go:"GO:0006869"(lipid transport)|go:"GO:0007283"(spermatogenesis)|go:"GO:0007342"(fusion of sperm to egg plasma membrane involved in single fertilization)|go:"GO:0008201"(heparin binding)|go:"GO:0009897"(external side of plasma membrane)|go:"GO:0010951"(negative regulation of endopeptidase activity)|go:"GO:0016020"(membrane)|go:"GO:0031091"(platelet alpha granule)|go:"GO:0031094"(platelet dense tubular network)|go:"GO:0031210"(phosphatidylcholine binding)|go:"GO:0032190"(acrosin binding)|go:"GO:0032991"(protein-containing complex)|go:"GO:0036024"(protein C inhibitor-TMPRSS7 complex)|go:"GO:0036025"(protein C inhibitor-TMPRSS11E complex)|go:"GO:0036026"(protein C inhibitor-PLAT complex)|go:"GO:0036027"(protein C inhibitor-PLAU complex)|go:"GO:0036028"(protein C inhibitor-thrombin complex)|go:"GO:0036029"(protein C inhibitor-KLK3 complex)|go:"GO:0036030"(protein C inhibitor-plasma kallikrein complex)|go:"GO:0051346"(negative regulation of hydrolase activity)|go:"GO:0061107"(seminal vesicle development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0097181"(protein C inhibitor-coagulation factor V complex)|go:"GO:0097182"(protein C inhibitor-coagulation factor Xa complex)|go:"GO:0097183"(protein C inhibitor-coagulation factor XI complex)|interpro:IPR000215(Protease inhibitor I4, serpin)|interpro:IPR023795|interpro:IPR023796|interpro:IPR036186|interpro:IPR042178|interpro:IPR042185|rcsb pdb:1LQ8|rcsb pdb:1PAI|rcsb pdb:2HI9|rcsb pdb:2OL2|rcsb pdb:2PAI|rcsb pdb:3DY0|reactome:R-HSA-140837|reactome:R-HSA-140875|dip:DIP-29869N refseq:NP_002017.1|refseq:NP_473375.2|refseq:NP_997639.1|refseq:NP_997641.1|refseq:NP_997643.1|refseq:NP_997647.1|refseq:NP_001293058.1|refseq:NP_001293059.1|refseq:NP_001293060.1|refseq:NP_001293061.1|refseq:XP_005246463.1|dip:DIP-29547N|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0008201"(heparin binding)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0009611"(response to wounding)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0014068"(positive regulation of phosphatidylinositol 3-kinase signaling)|go:"GO:0016324"(apical plasma membrane)|go:"GO:0016504"(peptidase activator activity)|go:"GO:0018149"(peptide cross-linking)|go:"GO:0019899"(enzyme binding)|go:"GO:0031012"(extracellular matrix)|go:"GO:0031093"(platelet alpha granule lumen)|go:"GO:0033622"(integrin activation)|go:"GO:0034446"(substrate adhesion-dependent cell spreading)|go:"GO:0035987"(endodermal cell differentiation)|go:"GO:0042802"(identical protein binding)|go:"GO:0043394"(proteoglycan binding)|go:"GO:0045773"(positive regulation of axon extension)|go:"GO:0048146"(positive regulation of fibroblast proliferation)|go:"GO:0051087"(chaperone binding)|go:"GO:0051702"(biological process involved in interaction with symbiont)|go:"GO:0062023"(collagen-containing extracellular matrix)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070372"(regulation of ERK1 and ERK2 cascade)|ensembl:ENSG00000115414(gene)|ensembl:ENST00000354785(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0001932"(regulation of protein phosphorylation)|go:"GO:0002020"(protease binding)|go:"GO:0005102"(signaling receptor binding)|go:"GO:0005178"(integrin binding)|go:"GO:0005201"(extracellular matrix structural constituent)|go:"GO:0005518"(collagen binding)|go:"GO:0005576"(extracellular region)|go:"GO:0005577"(fibrinogen complex)|go:"GO:0005604"(basement membrane)|go:"GO:0005615"(extracellular space)|go:"GO:0005788"(endoplasmic reticulum lumen)|go:"GO:0005793"(endoplasmic reticulum-Golgi intermediate compartment)|go:"GO:0006953"(acute-phase response)|go:"GO:0007044"(cell-substrate junction assembly)|go:"GO:0007155"(cell adhesion)|go:"GO:0007160"(cell-matrix adhesion)|go:"GO:0007161"(calcium-independent cell-matrix adhesion)|go:"GO:0007229"(integrin-mediated signaling pathway)|go:"GO:0007399"(nervous system development)|go:"GO:0007507"(heart development)|go:"GO:0070527"(platelet aggregation)|go:"GO:0071635"(negative regulation of transforming growth factor beta production)|go:"GO:0072378"(blood coagulation, fibrin clot formation)|go:"GO:0072562"(blood microparticle)|go:"GO:0097718"(disordered domain specific binding)|go:"GO:1901166"(neural crest cell migration involved in autonomic nervous system development)|go:"GO:1904237"(positive regulation of substrate-dependent cell migration, cell attachment to substrate)|interpro:IPR000083(Fibronectin, type I)|interpro:IPR000562(Type II fibronectin, collagen-binding)|interpro:IPR003961(Fibronectin, type III)|interpro:IPR013783(Immunoglobulin-like fold)|interpro:IPR013806(Kringle-like fold)|interpro:IPR036116|interpro:IPR036943|mint:P02751|rcsb pdb:1E88|rcsb pdb:1E8B|rcsb pdb:1FBR|rcsb pdb:1FNA|rcsb pdb:1FNF|rcsb pdb:1FNH|rcsb pdb:1J8K|rcsb pdb:1O9A|rcsb pdb:1OWW|rcsb pdb:1Q38|rcsb pdb:1QGB|rcsb pdb:1QO6|rcsb pdb:1TTF|rcsb pdb:1TTG|rcsb pdb:2CG6|rcsb pdb:2CG7|rcsb pdb:2CK2|rcsb pdb:2CKU|rcsb pdb:2EC3|rcsb pdb:2FN2|rcsb pdb:2FNB|rcsb pdb:2GEE|rcsb pdb:2H41|rcsb pdb:2H45|rcsb pdb:2HA1|rcsb pdb:2MNU|rcsb pdb:2N1K|rcsb pdb:2OCF|rcsb pdb:2RKY|rcsb pdb:2RKZ|rcsb pdb:2RL0|rcsb pdb:3CAL|rcsb pdb:3EJH|rcsb pdb:3GXE|rcsb pdb:3M7P|rcsb pdb:3MQL|rcsb pdb:3R8Q|rcsb pdb:3T1W|rcsb pdb:3ZRZ|rcsb pdb:4GH7|rcsb pdb:4JE4|rcsb pdb:4JEG|rcsb pdb:4LXO|rcsb pdb:4MMX|rcsb pdb:4MMY|rcsb pdb:4MMZ|rcsb pdb:4PZ5|rcsb pdb:5DC0|rcsb pdb:5DC4|rcsb pdb:5DC9|rcsb pdb:5DFT|rcsb pdb:5J6Z|rcsb pdb:5J7C|rcsb pdb:5M0A|rcsb pdb:5N47|rcsb pdb:5N48|rcsb pdb:6HNF|rcsb pdb:6MFA|rcsb pdb:6MSV|rcsb pdb:6NAJ|rcsb pdb:6XAX|rcsb pdb:6XAY|rcsb pdb:7NWL|reactome:R-HSA-114608|reactome:R-HSA-1474228|reactome:R-HSA-1474244|reactome:R-HSA-1566977|reactome:R-HSA-202733|reactome:R-HSA-2129379|reactome:R-HSA-216083|reactome:R-HSA-3000170|reactome:R-HSA-3000171|reactome:R-HSA-3000178|reactome:R-HSA-354192|reactome:R-HSA-354194|reactome:R-HSA-372708|reactome:R-HSA-381426|reactome:R-HSA-5674135|reactome:R-HSA-6785807|reactome:R-HSA-6802946|reactome:R-HSA-6802948|reactome:R-HSA-6802952|reactome:R-HSA-6802955|reactome:R-HSA-8874081|reactome:R-HSA-8957275|reactome:R-HSA-9649948|reactome:R-HSA-9656223 - - - figure legend:fig. 6c|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/07/19 2021/07/26 rogid:I0v9RvhA3PygP1kZRJzkP31jw5k9606 rogid:4arZu49X8b+dthqaX4DIh59V8h09606 rigid:nlsReRmYLwqzbXhRwzXygGeSwak false glutathione s tranferase tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)