#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:P45973 uniprotkb:Q5T3J3 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0018"(two hybrid) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27035020|imex:IM-29090-1 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Fig. 1A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)") - 2021/07/15 2021/07/15 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:v09Vi+vN6uAZvQXBZsjCQ0jFS74 false - sufficient binding region:542-769|mutation disrupting interaction strength:582-582,584-584 - - psi-mi:"MI:0396"(predetermined participant) psi-mi:"MI:0396"(predetermined participant) uniprotkb:A6NHR9 uniprotkb:Q5T3J3 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038785|imex:IM-29090-3 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:bi1bSSLkhUwgius5tQPfPV+LFOc false - necessary binding region:1-733|mutation:582-582,584-584|flag tag:?-? - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:A6NHR9 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038818|imex:IM-29090-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rigid:cxXGAn+HQIuwqYGb7nC1/9mp3lo false flag tag:?-?|mutation with complex effect:582-582,584-584 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:P45973 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038818|imex:IM-29090-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:cxXGAn+HQIuwqYGb7nC1/9mp3lo false flag tag:?-?|mutation with complex effect:582-582,584-584 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:P45973 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038828|imex:IM-29090-7 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - - figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:v09Vi+vN6uAZvQXBZsjCQ0jFS74 false flag tag:?-?|mutation with complex effect:747-749|mutation with complex effect:759-761|sufficient binding region:734-769 - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:Q13185 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038838|imex:IM-29090-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:Fig. 1B, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:CH2N9UpROPU04hYceg2ifb/NG4A false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:P83916 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038838|imex:IM-29090-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - - figure legend:Fig. 1B, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:CH2N9UpROPU04hYceg2ifb/NG4A false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:A6NHR9 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038838|imex:IM-29090-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) - - - figure legend:Fig. 1B, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rigid:CH2N9UpROPU04hYceg2ifb/NG4A false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:P45973 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038838|imex:IM-29090-9 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - - figure legend:Fig. 1B, Supp. Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:CH2N9UpROPU04hYceg2ifb/NG4A false flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q5T3J3 uniprotkb:P28074 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-357828|uniprotkb:Q16242|uniprotkb:Q6PEW2|intact:EBI-1237472|uniprotkb:Q7Z3B5|uniprotkb:Q9TNN9|uniprotkb:B2R4N9|uniprotkb:D3DS43|uniprotkb:B4DUM9|uniprotkb:Q86T01|uniprotkb:E9PAV2|ensembl:ENSP00000355325 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:psb5_human(display_long)|uniprotkb:PSMB5(gene name)|psi-mi:PSMB5(display_short)|uniprotkb:LMPX(gene name synonym)|uniprotkb:Proteasome epsilon chain(gene name synonym)|uniprotkb:Macropain epsilon chain(gene name synonym)|uniprotkb:Multicatalytic endopeptidase complex epsilon chain(gene name synonym)|uniprotkb:Proteasome subunit X(gene name synonym)|uniprotkb:Proteasome chain 6(gene name synonym)|uniprotkb:Proteasome subunit MB1(gene name synonym)|uniprotkb:MB1(gene name synonym)|uniprotkb:X(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 refseq:NP_001124197.1|refseq:NP_001138404.1|refseq:NP_002788.1|dip:DIP-27540N|reactome:R-HSA-187577|reactome:R-HSA-195253|reactome:R-HSA-202424|reactome:R-HSA-211733|reactome:R-HSA-2467813|reactome:R-HSA-2871837|reactome:R-HSA-349425|reactome:R-HSA-350562|reactome:R-HSA-382556|reactome:R-HSA-450408|reactome:R-HSA-4608870|reactome:R-HSA-4641257|reactome:R-HSA-4641258|reactome:R-HSA-5358346|reactome:R-HSA-5362768|reactome:R-HSA-5607761|reactome:R-HSA-5607764|reactome:R-HSA-5610780|reactome:R-HSA-5610783|reactome:R-HSA-5632684|reactome:R-HSA-5658442|reactome:R-HSA-5668541|reactome:R-HSA-5676590|reactome:R-HSA-5678895|reactome:R-HSA-5687128|reactome:R-HSA-5689603|reactome:R-HSA-5689880|reactome:R-HSA-68827|reactome:R-HSA-68949|reactome:R-HSA-69017|reactome:R-HSA-69481|reactome:R-HSA-69601|reactome:R-HSA-75815|reactome:R-HSA-8852276|reactome:R-HSA-8854050|reactome:R-HSA-8932339|reactome:R-HSA-8939236|reactome:R-HSA-8939902|reactome:R-HSA-8941858|reactome:R-HSA-8948751|reactome:R-HSA-8951664|reactome:R-HSA-9010553|reactome:R-HSA-9020702|reactome:R-HSA-9604323|reactome:R-HSA-983168|reactome:R-HSA-5610785|rcsb pdb:6KWY|rcsb pdb:6MSB|rcsb pdb:6MSD|rcsb pdb:6MSE|rcsb pdb:6MSG|rcsb pdb:6MSH|rcsb pdb:6MSJ|rcsb pdb:6MSK|rcsb pdb:6R70|rcsb pdb:6REY|rcsb pdb:6RGQ|rcsb pdb:6WJD|rcsb pdb:6WJN|rcsb pdb:6XMJ|reactome:R-HSA-1169091|reactome:R-HSA-1234176|reactome:R-HSA-1236974|reactome:R-HSA-1236978|reactome:R-HSA-174084|reactome:R-HSA-174113|reactome:R-HSA-174154|reactome:R-HSA-174178|reactome:R-HSA-174184|reactome:R-HSA-180534|reactome:R-HSA-180585|ensembl:ENSG00000100804(gene)|ensembl:ENST00000361611(transcript)|go:"GO:0000502"(proteasome complex)|go:"GO:0004175"(endopeptidase activity)|go:"GO:0004298"(threonine-type endopeptidase activity)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005839"(proteasome core complex)|go:"GO:0006508"(proteolysis)|go:"GO:0006979"(response to oxidative stress)|go:"GO:0008233"(peptidase activity)|go:"GO:0010499"(proteasomal ubiquitin-independent protein catabolic process)|go:"GO:0019774"(proteasome core complex, beta-subunit complex)|go:"GO:0043161"(proteasome-mediated ubiquitin-dependent protein catabolic process)|go:"GO:0070062"(extracellular exosome)|interpro:IPR000243(Peptidase T1A, proteasome beta-subunit)|interpro:IPR001353(20S proteasome, A and B subunits)|interpro:IPR016050(Proteasome, beta-type subunit, conserved site)|interpro:IPR023333|interpro:IPR029055|interpro:IPR037558|mint:P28074|rcsb pdb:4R3O|rcsb pdb:4R67|rcsb pdb:5A0Q|rcsb pdb:5GJQ|rcsb pdb:5GJR|rcsb pdb:5L4G|rcsb pdb:5L5W|rcsb pdb:5L5X|rcsb pdb:5L5Y|rcsb pdb:5L5Z|rcsb pdb:5L60|rcsb pdb:5L61|rcsb pdb:5L62|rcsb pdb:5L63|rcsb pdb:5L64|rcsb pdb:5LE5|rcsb pdb:5LEX|rcsb pdb:5LEY|rcsb pdb:5LEZ|rcsb pdb:5LF0|rcsb pdb:5LF1|rcsb pdb:5LF3|rcsb pdb:5LF4|rcsb pdb:5LF6|rcsb pdb:5LF7|rcsb pdb:5LN3|rcsb pdb:5M32|rcsb pdb:5T0C|rcsb pdb:5T0G|rcsb pdb:5T0H|rcsb pdb:5T0I|rcsb pdb:5T0J|rcsb pdb:5VFO|rcsb pdb:5VFP|rcsb pdb:5VFQ|rcsb pdb:5VFR|rcsb pdb:5VFS|rcsb pdb:5VFT|rcsb pdb:5VFU - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:73T59wniLri/465F3BhBvwL1/LM9606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:P63167 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-349105|uniprotkb:Q15701|ensembl:ENSP00000242577|ensembl:ENSP00000376296|ensembl:ENSP00000376297|ensembl:ENSP00000446614|ensembl:ENSP00000447907 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:dyl1_human(display_long)|uniprotkb:DYNLL1(gene name)|psi-mi:DYNLL1(display_short)|uniprotkb:DLC1(gene name synonym)|uniprotkb:DNCLC1(gene name synonym)|uniprotkb:HDLC1(gene name synonym)|uniprotkb:Dynein light chain LC8-type 1(gene name synonym)|uniprotkb:8 kDa dynein light chain(gene name synonym)|uniprotkb:Protein inhibitor of neuronal nitric oxide synthase(gene name synonym)|uniprotkb:DNCL1(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 refseq:NP_001032583.1|refseq:NP_001032584.1|refseq:NP_003737.1|go:"GO:0072686"(mitotic spindle)|go:"GO:0097110"(scaffold protein binding)|go:"GO:0097542"(ciliary tip)|go:"GO:0101003"(ficolin-1-rich granule membrane)|go:"GO:1904115"(axon cytoplasm)|go:"GO:2000582"(obsolete positive regulation of microtubule motor activity, plus-end-directed)|interpro:IPR001372(Dynein light chain, type 1 and 2)|interpro:IPR019763|interpro:IPR037177|mint:P63167|rcsb pdb:1CMI|rcsb pdb:3ZKE|rcsb pdb:3ZKF|rcsb pdb:6GZJ|rcsb pdb:6GZL|rcsb pdb:6RLB|rcsb pdb:6SC2|rcsb pdb:7D35|reactome:R-HSA-111446|reactome:R-HSA-141444|reactome:R-HSA-1632852|reactome:R-HSA-2132295|reactome:R-HSA-2467813|reactome:R-HSA-2500257|reactome:R-HSA-2565942|reactome:R-HSA-3371497|reactome:R-HSA-380259|reactome:R-HSA-380270|reactome:R-HSA-380284|reactome:R-HSA-380320|reactome:R-HSA-5620912|reactome:R-HSA-5620924|reactome:R-HSA-5663220|reactome:R-HSA-6798695|reactome:R-HSA-6807878|reactome:R-HSA-6811436|reactome:R-HSA-68877|reactome:R-HSA-8854518|reactome:R-HSA-9609690|reactome:R-HSA-9646399|reactome:R-HSA-9648025|go:"GO:0000776"(kinetochore)|go:"GO:0004857"(enzyme inhibitor activity)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005813"(centrosome)|go:"GO:0060271"(cilium assembly)|go:"GO:0005829"(cytosol)|go:"GO:0070821"(tertiary granule membrane)|go:"GO:0005868"(cytoplasmic dynein complex)|go:"GO:0005874"(microtubule)|go:"GO:0005886"(plasma membrane)|go:"GO:0005929"(cilium)|go:"GO:0006915"(apoptotic process)|go:"GO:0007017"(microtubule-based process)|go:"GO:0007286"(spermatid development)|go:"GO:0016020"(membrane)|go:"GO:0019899"(enzyme binding)|go:"GO:0021762"(substantia nigra development)|go:"GO:0030235"(nitric-oxide synthase regulator activity)|go:"GO:0030286"(dynein complex)|go:"GO:0035774"(positive regulation of insulin secretion involved in cellular response to glucose stimulus)|go:"GO:0042326"(negative regulation of phosphorylation)|go:"GO:0042802"(identical protein binding)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045019"(negative regulation of nitric oxide biosynthetic process)|go:"GO:0045505"(dynein intermediate chain binding)|go:"GO:0051959"(dynein light intermediate chain binding)|ensembl:ENSG00000088986(gene)|ensembl:ENST00000242577(transcript)|ensembl:ENST00000392508(transcript)|ensembl:ENST00000392509(transcript)|ensembl:ENST00000548342(transcript)|ensembl:ENST00000549989(transcript)|dip:DIP-33150N - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:Bra4LfaqYPMyo6xX9RD6G7Rdv809606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:P15170 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-948993|ensembl:ENSP00000399539|ensembl:ENSP00000454351|uniprotkb:Q96GF2|uniprotkb:J3KQG6 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:erf3a_human(display_long)|uniprotkb:G1 to S phase transition protein 1 homolog(gene name synonym)|uniprotkb:GSPT1(gene name)|psi-mi:GSPT1(display_short)|uniprotkb:ERF3A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 ensembl:ENSG00000103342(gene)|ensembl:ENST00000420576(transcript)|ensembl:ENST00000563468(transcript)|go:"GO:0000082"(G1/S transition of mitotic cell cycle)|go:"GO:0000184"(nuclear-transcribed mRNA catabolic process, nonsense-mediated decay)|go:"GO:0002184"(cytoplasmic translational termination)|go:"GO:0003723"(RNA binding)|go:"GO:0003747"(translation release factor activity)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0006412"(translation)|go:"GO:0006449"(regulation of translational termination)|go:"GO:0006479"(protein methylation)|go:"GO:0018444"(translation release factor complex)|interpro:IPR000795(Protein synthesis factor, GTP-binding)|interpro:IPR004160(Translation elongation factor EFTu/EF1A, C-terminal)|interpro:IPR004161(Translation elongation factor EFTu/EF1A, domain 2)|interpro:IPR009000(Translation elongation and initiation factors/Ribosomal, beta-barrel)|interpro:IPR009001(Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal)|interpro:IPR027417|mint:P15170|rcsb pdb:3E1Y|rcsb pdb:3J5Y|rcsb pdb:3KUI|rcsb pdb:4D61|rcsb pdb:5HXB|rcsb pdb:5LZT|rcsb pdb:6XK9|interpro:IPR031157|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-975956|reactome:R-HSA-975957|refseq:NP_001123479.1|refseq:NP_001123478.1 - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:ckNeqdEYS+CaYKzZWTBzKGJlmsI9606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:P46781 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-351206|uniprotkb:Q4QRK7|uniprotkb:Q9BVZ0|ensembl:ENSP00000302896|ensembl:ENSP00000375632|ensembl:ENSP00000375633|ensembl:ENSP00000478449|ensembl:ENSP00000479917|ensembl:ENSP00000480135|ensembl:ENSP00000480662|ensembl:ENSP00000481194|ensembl:ENSP00000481553|ensembl:ENSP00000481655|ensembl:ENSP00000481764|ensembl:ENSP00000481822|ensembl:ENSP00000482023|ensembl:ENSP00000482274|ensembl:ENSP00000482338|ensembl:ENSP00000482475|ensembl:ENSP00000483179|ensembl:ENSP00000484394|uniprotkb:A9C4C1 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:rs9_human(display_long)|uniprotkb:RPS9(gene name)|psi-mi:RPS9(display_short)|uniprotkb:Small ribosomal subunit protein uS4(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 refseq:NP_001004.2|refseq:NP_001308630.1|refseq:NP_001308631.1|refseq:NP_001308633.1|ensembl:ENSG00000170889(gene)|ensembl:ENSG00000274005(gene)|ensembl:ENSG00000274626(gene)|ensembl:ENSG00000274646(gene)|ensembl:ENSG00000274950(gene)|ensembl:ENSG00000275323(gene)|ensembl:ENSG00000277079(gene)|ensembl:ENSG00000277359(gene)|ensembl:ENSG00000278081(gene)|ensembl:ENSG00000278270(gene)|ensembl:ENST00000302907(transcript)|ensembl:ENST00000391752(transcript)|ensembl:ENST00000391753(transcript)|ensembl:ENST00000610826(transcript)|ensembl:ENST00000610953(transcript)|ensembl:ENST00000611921(transcript)|ensembl:ENST00000614737(transcript)|ensembl:ENST00000615346(transcript)|ensembl:ENST00000616082(transcript)|ensembl:ENST00000616536(transcript)|ensembl:ENST00000616839(transcript)|ensembl:ENST00000616877(transcript)|ensembl:ENST00000616928(transcript)|ensembl:ENST00000617291(transcript)|go:"GO:0005730"(nucleolus)|go:"GO:0005737"(cytoplasm)|ensembl:ENST00000618751(transcript)|go:"GO:0005829"(cytosol)|ensembl:ENST00000619229(transcript)|go:"GO:0005840"(ribosome)|go:"GO:0005925"(focal adhesion)|go:"GO:0006412"(translation)|go:"GO:0008284"(positive regulation of cell population proliferation)|go:"GO:0015935"(small ribosomal subunit)|go:"GO:0016020"(membrane)|go:"GO:0019843"(rRNA binding)|ensembl:ENST00000620720(transcript)|ensembl:ENST00000620940(transcript)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0045182"(translation regulator activity)|go:"GO:0045202"(synapse)|go:"GO:0045903"(positive regulation of translational fidelity)|go:"GO:0070062"(extracellular exosome)|go:"GO:1990904"(ribonucleoprotein complex)|go:"GO:1990932"(5.8S rRNA binding)|interpro:IPR001912(Ribosomal protein S4)|interpro:IPR002942(RNA-binding S4)|interpro:IPR005710(Ribosomal protein S4/S9, eukaryotic/archaeal)|go:"GO:0002181"(cytoplasmic translation)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|interpro:IPR018079|interpro:IPR022801|interpro:IPR036986|mint:P46781|rcsb pdb:4UG0|rcsb pdb:4V6X|rcsb pdb:5A2Q|rcsb pdb:5AJ0|rcsb pdb:5FLX|rcsb pdb:5LKS|rcsb pdb:5OA3|rcsb pdb:5T2C|rcsb pdb:5VYC|rcsb pdb:6EK0|rcsb pdb:6FEC|rcsb pdb:6G18|rcsb pdb:6G4S|rcsb pdb:6G4W|rcsb pdb:6G51|rcsb pdb:6G53|rcsb pdb:6G5H|rcsb pdb:6G5I|rcsb pdb:6IP5|rcsb pdb:6IP6|rcsb pdb:6IP8|rcsb pdb:6OLE|rcsb pdb:6OLF|rcsb pdb:6OLG|rcsb pdb:6OLI|rcsb pdb:6OLZ|rcsb pdb:6OM0|rcsb pdb:6OM7|rcsb pdb:6QZP|rcsb pdb:6XA1|rcsb pdb:6Y0G|go:"GO:0005634"(nucleus)|rcsb pdb:6Y2L|rcsb pdb:6Y57|rcsb pdb:6YBW|rcsb pdb:6Z6L|rcsb pdb:6Z6M|rcsb pdb:6Z6N|go:"GO:0005654"(nucleoplasm)|rcsb pdb:6ZLW|rcsb pdb:6ZM7|rcsb pdb:6ZME|rcsb pdb:6ZMI|rcsb pdb:6ZMO|rcsb pdb:6ZMT|rcsb pdb:6ZMW|rcsb pdb:6ZN5|rcsb pdb:6ZOJ|rcsb pdb:6ZOK|rcsb pdb:6ZON|rcsb pdb:6ZP4|rcsb pdb:6ZUO|rcsb pdb:6ZV6|rcsb pdb:6ZVH|rcsb pdb:6ZVJ|rcsb pdb:6ZXD|rcsb pdb:6ZXE|rcsb pdb:6ZXF|rcsb pdb:6ZXG|rcsb pdb:6ZXH|rcsb pdb:7A09|rcsb pdb:7K5I|reactome:R-HSA-156827|reactome:R-HSA-156902|reactome:R-HSA-1799339|reactome:R-HSA-192823|reactome:R-HSA-2408557|reactome:R-HSA-6790901|reactome:R-HSA-6791226|reactome:R-HSA-72649|reactome:R-HSA-72689|reactome:R-HSA-72695|reactome:R-HSA-72702|reactome:R-HSA-72706|reactome:R-HSA-72764|reactome:R-HSA-9010553|reactome:R-HSA-9633012|reactome:R-HSA-975956|reactome:R-HSA-975957 - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:PGNjkKMs8bMMOSOz2AQvwuCvO1A9606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:Q13185 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78176|ensembl:ENSP00000336687|ensembl:ENSP00000379670|uniprotkb:Q96CD7|uniprotkb:Q99409|uniprotkb:Q9BVS3|uniprotkb:Q9P0Z6 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx3_human(display_long)|uniprotkb:CBX3(gene name)|psi-mi:CBX3(display_short)|uniprotkb:Heterochromatin protein 1 homolog gamma(gene name synonym)|uniprotkb:Modifier 2 protein(gene name synonym)|uniprotkb:HECH(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 go:"GO:0000791"(euchromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001221"(transcription coregulator binding)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|ensembl:ENSG00000122565(gene)|ensembl:ENST00000337620(transcript)|ensembl:ENST00000396386(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000779"(condensed chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006338"(chromatin remodeling)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0019899"(enzyme binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0048511"(rhythmic process)|go:"GO:0090575"(RNA polymerase II transcription regulator complex)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|interpro:IPR038033|mint:Q13185|rcsb pdb:2L11|rcsb pdb:3DM1|rcsb pdb:3KUP|rcsb pdb:3TZD|go:"GO:0005637"(nuclear inner membrane)|rcsb pdb:6HW2|reactome:R-HSA-427389|reactome:R-HSA-73772|reactome:R-HSA-8953750|rcsb pdb:5T1I|refseq:NP_009207.2|refseq:NP_057671.2|refseq:XP_005249668.1|dip:DIP-5985N - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:6L5OQHfxCBkmPV5Z0XihmXx4mFQ9606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:P83916 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78129|uniprotkb:P23197|ensembl:ENSP00000225603|ensembl:ENSP00000377060 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx1_human(display_long)|uniprotkb:CBX1(gene name)|psi-mi:CBX1(display_short)|uniprotkb:CBX(gene name synonym)|uniprotkb:Heterochromatin protein 1 homolog beta(gene name synonym)|uniprotkb:Modifier 1 protein(gene name synonym)|uniprotkb:M31(gene name synonym)|uniprotkb:Heterochromatin protein p25(gene name synonym)|uniprotkb:p25beta(gene name synonym)|uniprotkb:HP1Hsbeta(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 ensembl:ENSG00000108468(gene)|ensembl:ENST00000225603(transcript)|ensembl:ENST00000393408(transcript)|go:"GO:0000775"(chromosome, centromeric region)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000785"(chromatin)|go:"GO:0000792"(heterochromatin)|go:"GO:0001939"(female pronucleus)|go:"GO:0001940"(male pronucleus)|go:"GO:0003682"(chromatin binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005819"(spindle)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0010369"(chromocenter)|go:"GO:0019899"(enzyme binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:1990226"(histone methyltransferase binding)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|mint:P83916|rcsb pdb:2FMM|rcsb pdb:3F2U|rcsb pdb:3Q6S|rcsb pdb:5T1G|rcsb pdb:6D07|rcsb pdb:6D08|reactome:R-HSA-9609690|refseq:NP_001120700.1|refseq:NP_006798.1|dip:DIP-28135N - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:W2npW/vFRcuTkStKpknsAP69q6I9606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:A6NHR9 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:P45973 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-78219|ensembl:ENSP00000209875|ensembl:ENSP00000401009|ensembl:ENSP00000449207|uniprotkb:B2R8T9 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:cbx5_human(display_long)|uniprotkb:CBX5(gene name)|psi-mi:CBX5(display_short)|uniprotkb:Heterochromatin protein 1 homolog alpha(gene name synonym)|uniprotkb:Antigen p25(gene name synonym)|uniprotkb:HP1A(gene name synonym) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 go:"GO:0035064"(methylated histone binding)|go:"GO:0035097"(histone methyltransferase complex)|go:"GO:0042802"(identical protein binding)|go:"GO:0043021"(ribonucleoprotein complex binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005721"(pericentric heterochromatin)|go:"GO:0005730"(nucleolus)|go:"GO:0006974"(cellular response to DNA damage stimulus)|go:"GO:0017053"(transcription repressor complex)|go:"GO:0044877"(protein-containing complex binding)|go:"GO:0045892"(negative regulation of transcription, DNA-templated)|go:"GO:0090734"(site of DNA damage)|go:"GO:0140297"(DNA-binding transcription factor binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000953(Chromo domain)|interpro:IPR008251(Chromo shadow)|interpro:IPR016197(Chromo domain-like)|interpro:IPR017984|interpro:IPR023779|interpro:IPR023780|go:"GO:0030674"(protein-macromolecule adaptor activity)|mint:P45973|rcsb pdb:3FDT|rcsb pdb:3I3C|reactome:R-HSA-4551638|reactome:R-HSA-8953750|reactome:R-HSA-983231|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000094916(gene)|ensembl:ENST00000209875(transcript)|ensembl:ENST00000439541(transcript)|ensembl:ENST00000550411(transcript)|go:"GO:0000118"(histone deacetylase complex)|go:"GO:0000122"(negative regulation of transcription by RNA polymerase II)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0000792"(heterochromatin)|go:"GO:0005634"(nucleus)|go:"GO:0005635"(nuclear envelope)|refseq:NP_001120793.1|refseq:NP_001120794.1|refseq:NP_036249.1|dip:DIP-5986N - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:yNQ+OVYYyR0Ls2cp6/xzBld1hyE9606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q5T3J3 uniprotkb:P84077 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 intact:EBI-447171|uniprotkb:P10947|uniprotkb:P32889|ensembl:ENSP00000272102|ensembl:ENSP00000440005|ensembl:ENSP00000442980 psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:arf1_human(display_long)|uniprotkb:ARF1(gene name)|psi-mi:ARF1(display_short) psi-mi:"MI:0007"(anti tag coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038934|imex:IM-29090-11 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 refseq:NP_001019397.1|refseq:NP_001019398.1|refseq:NP_001019399.1|refseq:NP_001649.1|dip:DIP-31597N|ensembl:ENSG00000143761(gene)|ensembl:ENST00000272102(transcript)|ensembl:ENST00000540651(transcript)|ensembl:ENST00000541182(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0000287"(magnesium ion binding)|go:"GO:0002090"(regulation of receptor internalization)|go:"GO:0003723"(RNA binding)|go:"GO:0003924"(GTPase activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005770"(late endosome)|go:"GO:0005778"(peroxisomal membrane)|go:"GO:0005802"(trans-Golgi network)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006878"(cellular copper ion homeostasis)|go:"GO:0006886"(intracellular protein transport)|go:"GO:0007015"(actin filament organization)|go:"GO:0014069"(postsynaptic density)|go:"GO:0016192"(vesicle-mediated transport)|go:"GO:0019003"(GDP binding)|go:"GO:0019904"(protein domain specific binding)|go:"GO:0030017"(sarcomere)|go:"GO:0030137"(COPI-coated vesicle)|go:"GO:0031252"(cell leading edge)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034315"(regulation of Arp2/3 complex-mediated actin nucleation)|go:"GO:0043005"(neuron projection)|go:"GO:0045807"(positive regulation of endocytosis)|go:"GO:0045956"(positive regulation of calcium ion-dependent exocytosis)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0050714"(positive regulation of protein secretion)|go:"GO:0055108"(Golgi to transport vesicle transport)|go:"GO:0060292"(long-term synaptic depression)|go:"GO:0060999"(positive regulation of dendritic spine development)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070142"(synaptic vesicle budding)|go:"GO:0097061"(dendritic spine organization)|go:"GO:0097212"(lysosomal membrane organization)|go:"GO:0098586"(cellular response to virus)|go:"GO:0098974"(postsynaptic actin cytoskeleton organization)|go:"GO:0098978"(glutamatergic synapse)|go:"GO:1902307"(positive regulation of sodium ion transmembrane transport)|go:"GO:1902824"(positive regulation of late endosome to lysosome transport)|go:"GO:0034379"(very-low-density lipoprotein particle assembly)|go:"GO:1903725"(regulation of phospholipid metabolic process)|go:"GO:1990386"(mitotic cleavage furrow ingression)|go:"GO:1990583"(phospholipase D activator activity)|interpro:IPR005225(Small GTP-binding protein)|go:"GO:1902953"(positive regulation of ER to Golgi vesicle-mediated transport)|interpro:IPR006689(ARF/SAR superfamily)|interpro:IPR027417|mint:P84077|rcsb pdb:1HUR|rcsb pdb:1RE0|rcsb pdb:1U81|rcsb pdb:3O47|rcsb pdb:4HMY|rcsb pdb:6CM9|rcsb pdb:6CRI|rcsb pdb:6D83|rcsb pdb:6D84|rcsb pdb:6DFF|rcsb pdb:6FAE|rcsb pdb:7MGE|reactome:R-HSA-1660499|reactome:R-HSA-1660514|reactome:R-HSA-167590|reactome:R-HSA-199992|reactome:R-HSA-2132295|reactome:R-HSA-432720|reactome:R-HSA-432722|reactome:R-HSA-6807878|reactome:R-HSA-6811434|reactome:R-HSA-6811438|reactome:R-HSA-8950505 - - - figure legend:Fig. 1F, Supp. Table 1|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rogid:zray9asm6VonxpuJpv0dRBspPt89606 rigid:GCSfppgL9gAP1zYmBZeH5VQaRGI false flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:A6NHR9 uniprotkb:Q5T3J3 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038955|imex:IM-29090-13 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Fig. 1G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:bi1bSSLkhUwgius5tQPfPV+LFOc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A6NHR9 uniprotkb:Q5T3J3 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038966|imex:IM-29090-15 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Fig. 1G|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/07/15 2021/07/20 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:bi1bSSLkhUwgius5tQPfPV+LFOc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A6NHR9 uniprotkb:Q5T3J3 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038981|imex:IM-29090-17 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0498"(prey) psi-mi:"MI:0496"(bait) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Supp. Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-htert_bj5)|taxid:9606(human htert_bj5) - 2021/07/15 2021/07/20 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:bi1bSSLkhUwgius5tQPfPV+LFOc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:A6NHR9 uniprotkb:Q5T3J3 intact:EBI-2801919|uniprotkb:O75141|uniprotkb:Q6AHX6|uniprotkb:Q9H6Q2|uniprotkb:Q6ZTQ8|intact:EBI-3192385|uniprotkb:Q9UG39|ensembl:ENSP00000326603 intact:EBI-473196|ensembl:ENSP00000358778|uniprotkb:Q86XS4|uniprotkb:Q8N3B6|uniprotkb:Q96HT4|uniprotkb:Q9NUM5|uniprotkb:Q9NV32 psi-mi:smhd1_human(display_long)|uniprotkb:KIAA0650(gene name synonym)|uniprotkb:SMCHD1(gene name)|psi-mi:SMCHD1(display_short) psi-mi:lrif1_human(display_long)|uniprotkb:Receptor-interacting factor 1(gene name synonym)|uniprotkb:LRIF1(gene name)|psi-mi:LRIF1(display_short)|uniprotkb:C1orf103(gene name synonym)|uniprotkb:RIF1(gene name synonym)|uniprotkb:HP1-binding protein enriched in inactive X chromosome protein 1(gene name synonym) psi-mi:"MI:0006"(anti bait coimmunoprecipitation) Nozawa et al. (2013) pubmed:23542155|imex:IM-29090 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27038985|imex:IM-29090-19 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_056110.2|ensembl:ENSG00000101596(gene)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:2000042"(negative regulation of double-strand break repair via homologous recombination)|go:"GO:2001034"(positive regulation of double-strand break repair via nonhomologous end joining)|interpro:IPR010935(SMCs flexible hinge)|interpro:IPR036277|interpro:IPR036890|interpro:IPR038892|mint:A6NHR9|rcsb pdb:6MW7|ensembl:ENST00000320876(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0003677"(DNA binding)|go:"GO:0005524"(ATP binding)|go:"GO:0006302"(double-strand break repair)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0035861"(site of double-strand break)|go:"GO:0042803"(protein homodimerization activity)|go:"GO:0043584"(nose development)|go:"GO:0045739"(positive regulation of DNA repair)|go:"GO:0060820"(inactivation of X chromosome by heterochromatin assembly)|go:"GO:0060821"(obsolete inactivation of X chromosome by DNA methylation) ensembl:ENSG00000121931(gene)|ensembl:ENST00000369763(transcript)|go:"GO:0001740"(Barr body)|go:"GO:0005654"(nucleoplasm)|go:"GO:0006355"(regulation of transcription, DNA-templated)|go:"GO:0009048"(dosage compensation by inactivation of X chromosome)|go:"GO:0016363"(nuclear matrix)|go:"GO:0034451"(centriolar satellite)|go:"GO:0042974"(retinoic acid receptor binding)|interpro:IPR026191|mint:Q5T3J3|refseq:NP_001006946.1|refseq:NP_060842.3 - - - figure legend:Supp. Fig. 5B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-htert_bj5)|taxid:9606(human htert_bj5) - 2021/07/15 2021/07/20 rogid:7tHwsz7p8pAqG9grnerpgMTmt3Q9606 rogid:0TZ2ePF1WLfBY9TO/jYZR4GiOKw9606 rigid:bi1bSSLkhUwgius5tQPfPV+LFOc false - - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot)