#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B intact:EBI-27087208 uniprotkb:P19338 refseq:NC_002058 intact:EBI-346967|uniprotkb:Q53SK1|uniprotkb:Q8NB06|uniprotkb:Q9UDG1|uniprotkb:Q9UCF0|intact:EBI-352553|ensembl:ENSP00000318195 psi-mi:polio virus rna(display_short)|psi-mi:EBI-27087208(display_long) psi-mi:nucl_human(display_long)|uniprotkb:NCL(gene name)|psi-mi:NCL(display_short)|uniprotkb:Protein C23(gene name synonym) psi-mi:"MI:0096"(pull down) Andreev et al. (2012) pubmed:22373920|imex:IM-29256 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-27087198|imex:IM-29256-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_005372.2|dip:DIP-89N|ensembl:ENSG00000115053(gene)|ensembl:ENST00000322723(transcript)|go:"GO:0001525"(angiogenesis)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005681"(spliceosomal complex)|go:"GO:0005694"(chromosome)|go:"GO:0005730"(nucleolus)|go:"GO:0005938"(cell cortex)|go:"GO:0008022"(protein C-terminus binding)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0042162"(telomeric DNA binding)|go:"GO:0042802"(identical protein binding)|go:"GO:0044547"(DNA topoisomerase binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0048026"(positive regulation of mRNA splicing, via spliceosome)|go:"GO:0048027"(mRNA 5'-UTR binding)|go:"GO:0070062"(extracellular exosome)|go:"GO:0071364"(cellular response to epidermal growth factor stimulus)|go:"GO:1901838"(positive regulation of transcription of nucleolar large rRNA by RNA polymerase I)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR003954(RNA recognition, region 1)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR034230|interpro:IPR034233|interpro:IPR034234|interpro:IPR034235|interpro:IPR035979|mint:P19338|rcsb pdb:2FC8|rcsb pdb:2FC9|rcsb pdb:2KRR|reactome:R-HSA-6791226 - - - figure legend:Fig 1A and text, Fig 2, Fig 3, Suppl fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/06/15 2021/09/28 - rogid:PbsEnzoLR4dES5SnMwx08Hr6yeo9606 - false binding-associated region:448-556|mutation decreasing interaction:495-497 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-27087208 uniprotkb:P05455 refseq:NC_002058 intact:EBI-358037|ensembl:ENSP00000260956|ensembl:ENSP00000386636|uniprotkb:Q15367|uniprotkb:Q53XJ4 psi-mi:polio virus rna(display_short)|psi-mi:EBI-27087208(display_long) psi-mi:la_human(display_long)|uniprotkb:SSB(gene name)|psi-mi:SSB(display_short)|uniprotkb:Sjoegren syndrome type B antigen(gene name synonym)|uniprotkb:La ribonucleoprotein(gene name synonym)|uniprotkb:La autoantigen(gene name synonym) psi-mi:"MI:0096"(pull down) Andreev et al. (2012) pubmed:22373920|imex:IM-29256 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-27087198|imex:IM-29256-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_003133.1|ensembl:ENSG00000138385(gene)|ensembl:ENST00000260956(transcript)|ensembl:ENST00000409333(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000781"(chromosome, telomeric region)|go:"GO:0001682"(tRNA 5'-leader removal)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0006400"(tRNA modification)|go:"GO:0006409"(tRNA export from nucleus)|go:"GO:0008033"(tRNA processing)|go:"GO:0008266"("poly(U) RNA binding")|go:"GO:0008334"(histone mRNA metabolic process)|go:"GO:0042780"(tRNA 3'-end processing)|go:"GO:0071045"(nuclear histone mRNA catabolic process)|refseq:NP_001281074.1|dip:DIP-29750N|go:"GO:0075522"(IRES-dependent viral translational initiation)|go:"GO:1903608"(protein localization to cytoplasmic stress granule)|go:"GO:1990825"(sequence-specific mRNA binding)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR002344(Lupus La protein)|interpro:IPR006630(RNA-binding protein Lupus La)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR014886(RNA binding motif)|interpro:IPR035979|interpro:IPR036388|interpro:IPR036390|mint:P05455|rcsb pdb:1OWX|rcsb pdb:1S79|rcsb pdb:1S7A|rcsb pdb:1YTY|rcsb pdb:1ZH5|rcsb pdb:2VOD|rcsb pdb:2VON|rcsb pdb:2VOO|rcsb pdb:2VOP|reactome:R-HSA-73980|reactome:R-HSA-749476 - - - figure legend:Fig 1A and text, Fig 2, Fig 3, Suppl fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/06/15 2021/09/28 - rogid:Lgpr3jgLWGk3AZzPwjB1swJRsoQ9606 - false binding-associated region:448-556|mutation decreasing interaction:495-497 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-27087208 uniprotkb:Q15365 refseq:NC_002058 intact:EBI-946095|uniprotkb:Q13157|uniprotkb:Q14975|ensembl:ENSP00000305556 psi-mi:polio virus rna(display_short)|psi-mi:EBI-27087208(display_long) psi-mi:pcbp1_human(display_long)|uniprotkb:PCBP1(gene name)|psi-mi:PCBP1(display_short)|uniprotkb:Alpha-CP1(gene name synonym)|uniprotkb:Nucleic acid-binding protein SUB2.3(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein E1(gene name synonym) psi-mi:"MI:0096"(pull down) Andreev et al. (2012) pubmed:22373920|imex:IM-29256 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-27087198|imex:IM-29256-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_006187.2|dip:DIP-38136N|ensembl:ENSG00000169564(gene)|ensembl:ENST00000303577(transcript)|go:"GO:0000981"(DNA-binding transcription factor activity, RNA polymerase II-specific)|go:"GO:0003697"(single-stranded DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0010468"(regulation of gene expression)|go:"GO:0016020"(membrane)|go:"GO:0016607"(nuclear speck)|go:"GO:0036464"(cytoplasmic ribonucleoprotein granule)|go:"GO:0039694"(viral RNA genome replication)|go:"GO:0045296"(cadherin binding)|go:"GO:0045944"(positive regulation of transcription by RNA polymerase II)|go:"GO:0051252"(regulation of RNA metabolic process)|go:"GO:0070062"(extracellular exosome)|go:"GO:0098847"(sequence-specific single stranded DNA binding)|interpro:IPR004087(K Homology)|interpro:IPR004088(K Homology, type 1)|interpro:IPR036612|mint:Q15365|rcsb pdb:1WVN|rcsb pdb:1ZTG|rcsb pdb:3VKE|reactome:R-HSA-72163|reactome:R-HSA-72203 - - - figure legend:Fig 1A and text, Fig 2, Fig 3, Suppl fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/06/15 2021/09/28 - rogid:x72fawo4plQ+ipfqIoREIDHc2bA9606 - false binding-associated region:448-556|mutation decreasing interaction:495-497 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-27087208 uniprotkb:P41250 refseq:NC_002058 intact:EBI-724143|uniprotkb:B3KQA2|uniprotkb:B4DIA0|ensembl:ENSP00000373918|uniprotkb:Q969Y1|intact:EBI-25629666|uniprotkb:A0A090N8G0 psi-mi:polio virus rna(display_short)|psi-mi:EBI-27087208(display_long) psi-mi:gars_human(display_long)|uniprotkb:GARS1(gene name)|psi-mi:GARS1(display_short)|uniprotkb:Diadenosine tetraphosphate synthetase(gene name synonym)|uniprotkb:GARS(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase(gene name synonym)|uniprotkb:Glycyl-tRNA synthetase 1(gene name synonym) psi-mi:"MI:0096"(pull down) Andreev et al. (2012) pubmed:22373920|imex:IM-29256 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-27087198|imex:IM-29256-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_002038.2|rcsb pdb:4KQE|rcsb pdb:4KR2|rcsb pdb:2ZT6|rcsb pdb:4KR3|rcsb pdb:4QEI|rcsb pdb:5E6M|reactome:R-HSA-379716|rcsb pdb:2ZT7|reactome:R-HSA-379726|rcsb pdb:2ZT8|rcsb pdb:2ZXF|ensembl:ENSG00000106105(gene)|ensembl:ENST00000389266(transcript)|go:"GO:0004081"("bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity")|go:"GO:0004820"(glycine-tRNA ligase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006418"(tRNA aminoacylation for protein translation)|go:"GO:0006426"(glycyl-tRNA aminoacylation)|go:"GO:0015966"(diadenosine tetraphosphate biosynthetic process)|go:"GO:0016740"(transferase activity)|go:"GO:0030141"(secretory granule)|go:"GO:0030424"(axon)|go:"GO:0042802"(identical protein binding)|go:"GO:0046983"(protein dimerization activity)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070150"(mitochondrial glycyl-tRNA aminoacylation)|interpro:IPR000738(WHEP-TRS)|interpro:IPR002314("Aminoacyl-tRNA synthetase, class II (G, H, P and S)")|interpro:IPR002315(Glycyl-tRNA synthetase, alpha2 dimer)|interpro:IPR004154(Anticodon-binding)|interpro:IPR006195(Aminoacyl-tRNA synthetase, class II)|interpro:IPR009068(S15/NS1, RNA-binding)|interpro:IPR027031|interpro:IPR033731|interpro:IPR036621|mint:P41250|rcsb pdb:2PME|rcsb pdb:2PMF|rcsb pdb:2Q5H|rcsb pdb:2Q5I|rcsb pdb:2ZT5|refseq:NP_001303701.1|dip:DIP-50471N - - - figure legend:Fig 1A and text, Fig 2, Fig 3, Suppl fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/06/15 2021/09/28 - rogid:bBlAPOMGXKsEvu0DxGKJJLjDI1s9606 - false binding-associated region:448-556|mutation decreasing interaction:495-497 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-27087208 uniprotkb:P26599 refseq:NC_002058 intact:EBI-350540|ensembl:ENSP00000014112|intact:EBI-744534|uniprotkb:Q9BUQ0 psi-mi:polio virus rna(display_short)|psi-mi:EBI-27087208(display_long) psi-mi:ptbp1_human(display_long)|uniprotkb:PTBP1(gene name)|psi-mi:PTBP1(display_short)|uniprotkb:PTB(gene name synonym)|uniprotkb:Heterogeneous nuclear ribonucleoprotein I(gene name synonym)|uniprotkb:57 kDa RNA-binding protein PPTB-1(gene name synonym) psi-mi:"MI:0096"(pull down) Andreev et al. (2012) pubmed:22373920|imex:IM-29256 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-27087198|imex:IM-29256-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_002810.1|refseq:NP_114367.1|refseq:NP_114368.1|go:"GO:0033119"(negative regulation of RNA splicing)|go:"GO:0035307"(positive regulation of protein dephosphorylation)|go:"GO:0036002"(pre-mRNA binding)|go:"GO:0043484"(regulation of RNA splicing)|go:"GO:0045595"(regulation of cell differentiation)|go:"GO:0016020"(membrane)|go:"GO:0048025"(negative regulation of mRNA splicing, via spliceosome)|go:"GO:0051148"(negative regulation of muscle cell differentiation)|go:"GO:0070062"(extracellular exosome)|go:"GO:0070886"(positive regulation of calcineurin-NFAT signaling cascade)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR000504(RNA recognition motif, RNP-1)|interpro:IPR006536(HnRNP-L/PTB/hephaestus splicing factor)|interpro:IPR012677(Nucleotide-binding, alpha-beta plait)|interpro:IPR021790|interpro:IPR034798|interpro:IPR035000|interpro:IPR035001|interpro:IPR035979|mint:P26599|rcsb pdb:1QM9|rcsb pdb:1SJQ|ensembl:ENSG00000011304(gene)|ensembl:ENST00000349038(transcript)|go:"GO:0000381"(regulation of alternative mRNA splicing, via spliceosome)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005730"(nucleolus)|go:"GO:0006397"(mRNA processing)|go:"GO:0008187"(poly-pyrimidine tract binding)|go:"GO:0008380"(RNA splicing)|rcsb pdb:2AD9|rcsb pdb:2ADB|rcsb pdb:2ADC|rcsb pdb:2EVZ|rcsb pdb:2N3O|rcsb pdb:3ZZY|rcsb pdb:3ZZZ|reactome:R-HSA-6803529|reactome:R-HSA-72163|reactome:R-HSA-72203|rcsb pdb:1SJR - - - figure legend:Fig 1A and text, Fig 2, Fig 3, Suppl fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/06/15 2021/09/28 - rogid:fkSnYJELgHxDP0oAQEjBmSX0HIs9606 - false binding-associated region:448-556|mutation decreasing interaction:495-497 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) intact:EBI-27087208 uniprotkb:O75534 refseq:NC_002058 intact:EBI-719186|uniprotkb:O94961|uniprotkb:Q5TF04|uniprotkb:Q5TF05|uniprotkb:Q68DI9|uniprotkb:Q9Y2S4|uniprotkb:E9PGZ0|uniprotkb:Q68DF1|intact:EBI-1059183|ensembl:ENSP00000351329|ensembl:ENSP00000432958|uniprotkb:A8K281|uniprotkb:G5E9Q2 psi-mi:polio virus rna(display_short)|psi-mi:EBI-27087208(display_long) psi-mi:csde1_human(display_long)|uniprotkb:Protein UNR(gene name synonym)|uniprotkb:N-ras upstream gene protein(gene name synonym)|uniprotkb:CSDE1(gene name)|psi-mi:CSDE1(display_short)|uniprotkb:D1S155E(gene name synonym)|uniprotkb:KIAA0885(gene name synonym)|uniprotkb:NRU(gene name synonym)|uniprotkb:UNR(gene name synonym) psi-mi:"MI:0096"(pull down) Andreev et al. (2012) pubmed:22373920|imex:IM-29256 taxid:12081(pol1m)|taxid:12081("Poliovirus type 1 (strain Mahoney)") taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0469"(IntAct) intact:EBI-27087198|imex:IM-29256-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0320"(ribonucleic acid) psi-mi:"MI:0326"(protein) - refseq:NP_001007554.1|refseq:NP_001123995.1|refseq:NP_001229820.1|refseq:NP_001229821.1|refseq:NP_001229822.1|refseq:NP_009089.4|ensembl:ENSG00000009307(gene)|ensembl:ENST00000358528(transcript)|ensembl:ENST00000534699(transcript)|go:"GO:0000932"(P-body)|go:"GO:0003723"(RNA binding)|go:"GO:0005794"(Golgi apparatus)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0008584"(male gonad development)|go:"GO:0010494"(cytoplasmic stress granule)|go:"GO:0034063"(stress granule assembly)|go:"GO:0035613"(RNA stem-loop binding)|go:"GO:0070937"(CRD-mediated mRNA stability complex)|go:"GO:0070966"(nuclear-transcribed mRNA catabolic process, no-go decay)|go:"GO:0075522"(IRES-dependent viral translational initiation)|interpro:IPR002059(Cold-shock protein, DNA-binding)|interpro:IPR011129(Cold shock protein)|interpro:IPR019844|interpro:IPR024642|mint:O75534|rcsb pdb:1WFQ|rcsb pdb:1X65|rcsb pdb:2YTV|rcsb pdb:2YTX|rcsb pdb:2YTY|interpro:IPR012340(Nucleic acid-binding, OB-fold) - - - figure legend:Fig 1A and text, Fig 2, Fig 3, Suppl fig2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:-1(in vitro)|taxid:-1(In vitro) - 2021/06/15 2021/09/28 - rogid:fpL1bONjNXyXjIO/akUIIoeEGTc9606 - false binding-associated region:448-556|mutation decreasing interaction:495-497 - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification)