#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q9BY44	uniprotkb:Q9NZJ5	intact:EBI-1776615|uniprotkb:Q5QTR2|uniprotkb:Q7Z4E9|uniprotkb:Q8NFM1|uniprotkb:Q96EW9|uniprotkb:Q96K81|uniprotkb:A8MPS6|uniprotkb:B4DF96|uniprotkb:B4DQ14|uniprotkb:D3DNI9|ensembl:ENSP00000417229	intact:EBI-766076|uniprotkb:A0AVH2|uniprotkb:A0AVH1|uniprotkb:B2RCU9|uniprotkb:Q53QY0|uniprotkb:Q53SB1|uniprotkb:O95846|ensembl:ENSP00000307235	psi-mi:eif2a_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short)|uniprotkb:CDA02(orf name)|uniprotkb:MSTP004(orf name)|uniprotkb:MSTP089(orf name)|uniprotkb:65 kDa eukaryotic translation initiation factor 2A(gene name synonym)	psi-mi:e2ak3_human(display_long)|uniprotkb:PRKR-like endoplasmic reticulum kinase(gene name synonym)|uniprotkb:Pancreatic eIF2-alpha kinase(gene name synonym)|uniprotkb:EIF2AK3(gene name)|psi-mi:EIF2AK3(display_short)|uniprotkb:PEK(gene name synonym)|uniprotkb:PERK(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Brunelli et al. (2012)	imex:IM-29001|pubmed:22268531	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26989858|imex:IM-29001-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114414.2|refseq:NP_001305972.1|refseq:NP_001305973.1|refseq:NP_001305974.1|refseq:NP_001305975.1|dip:DIP-40272N|ensembl:ENSG00000144895(gene)|ensembl:ENST00000460851(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9BY44	refseq:NP_004827.4|rcsb pdb:4YZS|rcsb pdb:5SV7|rcsb pdb:7MF0|reactome:R-HSA-381042|rcsb pdb:4X7O|ensembl:ENSG00000172071(gene)|ensembl:ENST00000303236(transcript)|go:"GO:0001501"(skeletal system development)|go:"GO:0001503"(ossification)|go:"GO:0001525"(angiogenesis)|go:"GO:0002063"(chondrocyte development)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005783"(endoplasmic reticulum)|go:"GO:0005789"(endoplasmic reticulum membrane)|go:"GO:0005829"(cytosol)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0006919"(activation of cysteine-type endopeptidase activity involved in apoptotic process)|go:"GO:0006983"(ER overload response)|go:"GO:0007029"(endoplasmic reticulum organization)|go:"GO:0010575"(positive regulation of vascular endothelial growth factor production)|go:"GO:0010628"(positive regulation of gene expression)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019903"(protein phosphatase binding)|go:"GO:0030176"(integral component of endoplasmic reticulum membrane)|go:"GO:0030282"(bone mineralization)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0031018"(endocrine pancreas development)|go:"GO:0031642"(negative regulation of myelination)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034976"(response to endoplasmic reticulum stress)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0018105"(peptidyl-serine phosphorylation)|go:"GO:0019722"(calcium-mediated signaling)|go:"GO:0019899"(enzyme binding)|go:"GO:0036499"(PERK-mediated unfolded protein response)|go:"GO:0042149"(cellular response to glucose starvation)|go:"GO:0042802"(identical protein binding)|go:"GO:0045943"(positive regulation of transcription by RNA polymerase I)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048009"(insulin-like growth factor receptor signaling pathway)|go:"GO:0048471"(perinuclear region of cytoplasm)|go:"GO:0060734"(regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation)|go:"GO:0070417"(cellular response to cold)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900182"(positive regulation of protein localization to nucleus)|go:"GO:1902235"(regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway)|go:"GO:1990737"(response to manganese-induced endoplasmic reticulum stress)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR011047(Quinonprotein alcohol dehydrogenase-like)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|mint:Q9NZJ5|rcsb pdb:4G31|rcsb pdb:4G34|rcsb pdb:4M7I|rcsb pdb:4X7H|rcsb pdb:4X7J|rcsb pdb:4X7K|rcsb pdb:4X7L|rcsb pdb:4X7N|go:"GO:0051879"(Hsp90 protein binding)	-	-	-	figure legend:4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ht_29)|taxid:9606(Homo sapiens HT-29 caucasian women with colon adenocarcinoma)	-	2021/06/09	2021/06/09	rogid:67hYEz0CrhoQ7SfXxZdOWqKzil89606	rogid:sjPIYQzmbvq1fvSgn0HR781yf9w9606	rigid:HOMjra8c6vhrZkNH0KiGRFXuIZ0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9P2K8	uniprotkb:Q9BY44	intact:EBI-746616|uniprotkb:Q69YL7|uniprotkb:Q6DC97|uniprotkb:Q96GN6|uniprotkb:Q9H5K1|uniprotkb:Q9NSQ3|uniprotkb:Q9NSZ5|uniprotkb:Q9UJ56|uniprotkb:C9JEC4|ensembl:ENSP00000263791	intact:EBI-1776615|uniprotkb:Q5QTR2|uniprotkb:Q7Z4E9|uniprotkb:Q8NFM1|uniprotkb:Q96EW9|uniprotkb:Q96K81|uniprotkb:A8MPS6|uniprotkb:B4DF96|uniprotkb:B4DQ14|uniprotkb:D3DNI9|ensembl:ENSP00000417229	psi-mi:e2ak4_human(display_long)|uniprotkb:GCN2-like protein(gene name synonym)|uniprotkb:EIF2AK4(gene name)|psi-mi:EIF2AK4(display_short)|uniprotkb:GCN2(gene name synonym)|uniprotkb:KIAA1338(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2-alpha kinase 4(gene name synonym)	psi-mi:eif2a_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short)|uniprotkb:CDA02(orf name)|uniprotkb:MSTP004(orf name)|uniprotkb:MSTP089(orf name)|uniprotkb:65 kDa eukaryotic translation initiation factor 2A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Brunelli et al. (2012)	imex:IM-29001|pubmed:22268531	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26989862|imex:IM-29001-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001013725.2|ensembl:ENSG00000128829(gene)|ensembl:ENST00000263791(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0000077"(DNA damage checkpoint signaling)|go:"GO:0001934"(positive regulation of protein phosphorylation)|go:"GO:0002230"(positive regulation of defense response to virus by host)|go:"GO:0002250"(adaptive immune response)|go:"GO:0002286"(T cell activation involved in immune response)|go:"GO:0002821"(positive regulation of adaptive immune response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005844"(polysome)|go:"GO:0006446"(regulation of translational initiation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0007049"(cell cycle)|go:"GO:0036492"(eiF2alpha phosphorylation in response to endoplasmic reticulum stress)|go:"GO:0039520"(induction by virus of host autophagy)|go:"GO:0044828"(negative regulation by host of viral genome replication)|go:"GO:0045665"(negative regulation of neuron differentiation)|go:"GO:0045947"(negative regulation of translational initiation)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0051607"(defense response to virus)|go:"GO:0060259"(regulation of feeding behavior)|go:"GO:0070417"(cellular response to cold)|go:"GO:0071264"(positive regulation of translational initiation in response to starvation)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140469"(GCN2-mediated signaling)|go:"GO:1900273"(positive regulation of long-term synaptic potentiation)|go:"GO:1990138"(neuron projection extension)|go:"GO:1990253"(cellular response to leucine starvation)|interpro:IPR000719(Protein kinase, core)|go:"GO:0007612"(learning)|go:"GO:0007616"(long-term memory)|go:"GO:0010998"(regulation of translational initiation by eIF2 alpha phosphorylation)|go:"GO:0019081"(viral translation)|go:"GO:0022626"(cytosolic ribosome)|go:"GO:0032057"(negative regulation of translational initiation in response to stress)|go:"GO:0032792"(negative regulation of CREB transcription factor activity)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0034644"(cellular response to UV)|interpro:IPR006575(RWD)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR016135(Ubiquitin-conjugating enzyme/RWD-like)|interpro:IPR016255(Serine/threonine-protein kinase, GCN2)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR024435|interpro:IPR036621|interpro:IPR041715|rcsb pdb:6N3L|rcsb pdb:6N3N|rcsb pdb:6N3O|rcsb pdb:7E2K|rcsb pdb:7E2M|reactome:R-HSA-9633012	refseq:NP_114414.2|refseq:NP_001305972.1|refseq:NP_001305973.1|refseq:NP_001305974.1|refseq:NP_001305975.1|dip:DIP-40272N|ensembl:ENSG00000144895(gene)|ensembl:ENST00000460851(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9BY44	-	-	-	figure legend:4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ht_29)|taxid:9606(Homo sapiens HT-29 caucasian women with colon adenocarcinoma)	-	2021/06/09	2021/06/09	rogid:rPY2wmZ1ol512887sv3BEZeagcE9606	rogid:67hYEz0CrhoQ7SfXxZdOWqKzil89606	rigid:LQm80Bd3inEqBTLFkenDkd8tW6M	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:Q9BY44	uniprotkb:Q9BQI3	intact:EBI-1776615|uniprotkb:Q5QTR2|uniprotkb:Q7Z4E9|uniprotkb:Q8NFM1|uniprotkb:Q96EW9|uniprotkb:Q96K81|uniprotkb:A8MPS6|uniprotkb:B4DF96|uniprotkb:B4DQ14|uniprotkb:D3DNI9|ensembl:ENSP00000417229	intact:EBI-640377|uniprotkb:Q8NBW3|uniprotkb:Q9HC02|uniprotkb:Q9NYE0|uniprotkb:Q9P0V6|uniprotkb:Q9P1J5|uniprotkb:Q9P2H8|uniprotkb:Q9UHG4|uniprotkb:A8K2R2|uniprotkb:Q549K6|ensembl:ENSP00000199389	psi-mi:eif2a_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short)|uniprotkb:CDA02(orf name)|uniprotkb:MSTP004(orf name)|uniprotkb:MSTP089(orf name)|uniprotkb:65 kDa eukaryotic translation initiation factor 2A(gene name synonym)	psi-mi:e2ak1_human(display_long)|uniprotkb:Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase(gene name synonym)|uniprotkb:Hemin-sensitive initiation factor 2-alpha kinase(gene name synonym)|uniprotkb:Heme-regulated inhibitor(gene name synonym)|uniprotkb:Heme-controlled repressor(gene name synonym)|uniprotkb:EIF2AK1(gene name)|psi-mi:EIF2AK1(display_short)|uniprotkb:HRI(gene name synonym)|uniprotkb:KIAA1369(gene name synonym)|uniprotkb:PRO1362(orf name)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Brunelli et al. (2012)	imex:IM-29001|pubmed:22268531	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26989877|imex:IM-29001-4	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_114414.2|refseq:NP_001305972.1|refseq:NP_001305973.1|refseq:NP_001305974.1|refseq:NP_001305975.1|dip:DIP-40272N|ensembl:ENSG00000144895(gene)|ensembl:ENST00000460851(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9BY44	refseq:NP_001127807.1|refseq:NP_055228.2|go:"GO:0045993"(negative regulation of translational initiation by iron)|go:"GO:0046501"(protoporphyrinogen IX metabolic process)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0046986"(negative regulation of hemoglobin biosynthetic process)|go:"GO:0055072"(iron ion homeostasis)|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:0140467"(integrated stress response signaling)|go:"GO:0140468"(HRI-mediated signaling)|ensembl:ENSG00000086232(gene)|ensembl:ENST00000199389(transcript)|go:"GO:0002526"(acute inflammatory response)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0006909"(phagocytosis)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0010999"(regulation of eIF2 alpha phosphorylation by heme)|go:"GO:0020037"(heme binding)|go:"GO:0030225"(macrophage differentiation)|go:"GO:0042803"(protein homodimerization activity)|reactome:R-HSA-9648895|go:"GO:1990641"(response to iron ion starvation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)	-	-	-	figure legend:4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ht_29)|taxid:9606(Homo sapiens HT-29 caucasian women with colon adenocarcinoma)	-	2021/06/09	2021/06/09	rogid:67hYEz0CrhoQ7SfXxZdOWqKzil89606	rogid:MeYyxgmklJVF/JTjyfZ8UaHGcGc9606	rigid:yhSNobbqB+6PvjIEKR3fUVEc7gc	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)
uniprotkb:P19525	uniprotkb:Q9BY44	intact:EBI-640775|uniprotkb:D6W584|uniprotkb:Q52M43|uniprotkb:Q9UIR4|uniprotkb:A8K3P0|ensembl:ENSP00000233057|ensembl:ENSP00000378559|ensembl:ENSP00000497534|ensembl:ENSP00000505138|ensembl:ENSP00000505772|ensembl:ENSP00000506024|uniprotkb:E9PC80|uniprotkb:Q7Z6F6	intact:EBI-1776615|uniprotkb:Q5QTR2|uniprotkb:Q7Z4E9|uniprotkb:Q8NFM1|uniprotkb:Q96EW9|uniprotkb:Q96K81|uniprotkb:A8MPS6|uniprotkb:B4DF96|uniprotkb:B4DQ14|uniprotkb:D3DNI9|ensembl:ENSP00000417229	psi-mi:e2ak2_human(display_long)|uniprotkb:Interferon-inducible RNA-dependent protein kinase(gene name synonym)|uniprotkb:Eukaryotic translation initiation factor 2-alpha kinase 2(gene name synonym)|uniprotkb:Protein kinase RNA-activated(gene name synonym)|uniprotkb:p68 kinase(gene name synonym)|uniprotkb:P1/eIF-2A protein kinase(gene name synonym)|uniprotkb:EIF2AK2(gene name)|psi-mi:EIF2AK2(display_short)|uniprotkb:PKR(gene name synonym)|uniprotkb:PRKR(gene name synonym)|uniprotkb:Tyrosine-protein kinase EIF2AK2(gene name synonym)	psi-mi:eif2a_human(display_long)|uniprotkb:EIF2A(gene name)|psi-mi:EIF2A(display_short)|uniprotkb:CDA02(orf name)|uniprotkb:MSTP004(orf name)|uniprotkb:MSTP089(orf name)|uniprotkb:65 kDa eukaryotic translation initiation factor 2A(gene name synonym)	psi-mi:"MI:0006"(anti bait coimmunoprecipitation)	Brunelli et al. (2012)	imex:IM-29001|pubmed:22268531	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-26989881|imex:IM-29001-6	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001129124.1|refseq:NP_001129123.1|refseq:NP_002750.1|ensembl:ENSG00000055332(gene)|ensembl:ENST00000233057(transcript)|ensembl:ENST00000395127(transcript)|ensembl:ENST00000647926(transcript)|ensembl:ENST00000679507(transcript)|ensembl:ENST00000681463(transcript)|ensembl:ENST00000681507(transcript)|go:"GO:0000186"(obsolete activation of MAPKK activity)|go:"GO:0001819"(positive regulation of cytokine production)|go:"GO:0003723"(RNA binding)|go:"GO:0003725"(double-stranded RNA binding)|go:"GO:0004672"(protein kinase activity)|go:"GO:0004674"(protein serine/threonine kinase activity)|go:"GO:0004694"(eukaryotic translation initiation factor 2alpha kinase activity)|go:"GO:0004714"(transmembrane receptor protein tyrosine kinase activity)|go:"GO:0004715"(non-membrane spanning protein tyrosine kinase activity)|go:"GO:0005524"(ATP binding)|go:"GO:0005634"(nucleus)|go:"GO:0005737"(cytoplasm)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0008285"(negative regulation of cell population proliferation)|go:"GO:0009615"(response to virus)|go:"GO:0016020"(membrane)|go:"GO:0017148"(negative regulation of translation)|go:"GO:0019888"(protein phosphatase regulator activity)|go:"GO:0030968"(endoplasmic reticulum unfolded protein response)|go:"GO:0032722"(positive regulation of chemokine production)|go:"GO:0032874"(positive regulation of stress-activated MAPK cascade)|go:"GO:0033689"(negative regulation of osteoblast proliferation)|go:"GO:0034198"(cellular response to amino acid starvation)|go:"GO:0035455"(response to interferon-alpha)|go:"GO:0042802"(identical protein binding)|go:"GO:0043066"(negative regulation of apoptotic process)|go:"GO:0045071"(negative regulation of viral genome replication)|go:"GO:0045087"(innate immune response)|go:"GO:0046777"(protein autophosphorylation)|go:"GO:0048471"(perinuclear region of cytoplasm)|interpro:IPR014720(Double-stranded RNA-binding-like)|interpro:IPR017441(Protein kinase ATP binding, conserved site)|interpro:IPR044452|interpro:IPR044453|mint:P19525|rcsb pdb:1QU6|rcsb pdb:2A19|rcsb pdb:2A1A|rcsb pdb:3UIU|rcsb pdb:6D3K|go:"GO:0051092"(positive regulation of NF-kappaB transcription factor activity)|rcsb pdb:6D3L|reactome:R-HSA-1169408|go:"GO:0051607"(defense response to virus)|reactome:R-HSA-169131|go:"GO:0106310"(protein serine kinase activity)|go:"GO:0106311"|go:"GO:1900225"(regulation of NLRP3 inflammasome complex assembly)|go:"GO:1901224"(positive regulation of NIK/NF-kappaB signaling)|go:"GO:1901532"(regulation of hematopoietic progenitor cell differentiation)|go:"GO:1902033"(regulation of hematopoietic stem cell proliferation)|go:"GO:1902036"(regulation of hematopoietic stem cell differentiation)|interpro:IPR000719(Protein kinase, core)|interpro:IPR008271(Serine/threonine protein kinase, active site)|interpro:IPR011009(Protein kinase-like)|dip:DIP-2657N|refseq:XP_011531289.1	refseq:NP_114414.2|refseq:NP_001305972.1|refseq:NP_001305973.1|refseq:NP_001305974.1|refseq:NP_001305975.1|dip:DIP-40272N|ensembl:ENSG00000144895(gene)|ensembl:ENST00000460851(transcript)|go:"GO:0000049"(tRNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003743"(translation initiation factor activity)|go:"GO:0005615"(extracellular space)|go:"GO:0005737"(cytoplasm)|go:"GO:0005850"(eukaryotic translation initiation factor 2 complex)|go:"GO:0006417"(regulation of translation)|go:"GO:0006468"(protein phosphorylation)|go:"GO:0009967"(positive regulation of signal transduction)|go:"GO:0022627"(cytosolic small ribosomal subunit)|go:"GO:0032933"(SREBP signaling pathway)|go:"GO:0042255"(ribosome assembly)|go:"GO:0043022"(ribosome binding)|go:"GO:0045296"(cadherin binding)|go:"GO:0072562"(blood microparticle)|go:"GO:1990928"(response to amino acid starvation)|interpro:IPR011387(Translation initiation factor eIF-2A)|interpro:IPR013979(Eukaryotic translation initiation factor 2A, central region)|interpro:IPR015943(WD40/YVTN repeat-like)|interpro:IPR036322|mint:Q9BY44	-	-	-	figure legend:4a|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-ht_29)|taxid:9606(Homo sapiens HT-29 caucasian women with colon adenocarcinoma)	-	2021/06/09	2021/06/09	rogid:2Pc405Bc/xKDHC1O24GhGC5JJzU9606	rogid:67hYEz0CrhoQ7SfXxZdOWqKzil89606	rigid:S9RPc3NqQNykLQPykM6qi1At+p0	false	-	-	-	-	psi-mi:"MI:0113"(western blot)	psi-mi:"MI:0113"(western blot)