#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:Q7L0Q8	uniprotkb:Q7Z6I6	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-2814810|uniprotkb:Q5SY52|uniprotkb:Q6ZML6|uniprotkb:Q5SY53|uniprotkb:Q7Z3J8|uniprotkb:Q86XI7|uniprotkb:Q5SY54|ensembl:ENSP00000356992	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:rhg30_human(display_long)|uniprotkb:ARHGAP30(gene name)|psi-mi:ARHGAP30(display_short)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym)	psi-mi:"MI:0018"(two hybrid)	Naji et al. (2011)	pubmed:21565175|imex:IM-28936	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26970883|imex:IM-28936-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	refseq:XP_011507693.1|refseq:NP_001020769.1|refseq:NP_859071.2|refseq:NP_001274529.1|refseq:NP_001274531.1|ensembl:ENSG00000186517(gene)|ensembl:ENST00000368013(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|go:"GO:0005829"(cytosol)|refseq:XP_005245130.1	-	-	-	full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2021/05/06	2021/05/06	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:L0Pbx3s9V/lw/NAiHZHnvXwI8Hw9606	rigid:7B6PwlB8b6Ym5j9Efv90qpbG1/k	false	mutation:107-107	-	-	-	psi-mi:"MI:0078"(nucleotide sequence identification)	psi-mi:"MI:0078"(nucleotide sequence identification)
uniprotkb:Q7L0Q8	uniprotkb:Q7Z6I6-2	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-26970905	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:q7z6i6-2(display_long)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym)|uniprotkb:S-30(isoform synonym)|uniprotkb:S-ARHGAP30(isoform synonym)|uniprotkb:ARHGAP30(gene name)|psi-mi:ARHGAP30(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Naji et al. (2011)	pubmed:21565175|imex:IM-28936	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26970893|imex:IM-28936-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	intact:EBI-2814810(isoform-parent)	-	-	-	figure legend:Fig. 1B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/05/06	2021/05/06	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:mFIzoN7LxL49XyY9zaJDjlZk0k89606	rigid:DQt7u9r11ExBY1m5UsTspmlWH30	false	myc tag:n-n|mutation with no effect:63-63|necessary binding region:1-47|mutation with no effect:80-80|mutation disrupting interaction strength:83-83|mutation with no effect:86-86|mutation with no effect:107-107	flag tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7L0Q8	uniprotkb:Q7Z6I6-2	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-26970905	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:q7z6i6-2(display_long)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym)|uniprotkb:S-30(isoform synonym)|uniprotkb:S-ARHGAP30(isoform synonym)|uniprotkb:ARHGAP30(gene name)|psi-mi:ARHGAP30(display_short)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Naji et al. (2011)	pubmed:21565175|imex:IM-28936	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26970983|imex:IM-28936-7	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	intact:EBI-2814810(isoform-parent)	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/05/06	2021/05/06	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:mFIzoN7LxL49XyY9zaJDjlZk0k89606	rigid:DQt7u9r11ExBY1m5UsTspmlWH30	false	flag tag:n-n	myc tag:n-n|sufficient binding region:216-890	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7L0Q8	uniprotkb:Q7Z6I6	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-2814810|uniprotkb:Q5SY52|uniprotkb:Q6ZML6|uniprotkb:Q5SY53|uniprotkb:Q7Z3J8|uniprotkb:Q86XI7|uniprotkb:Q5SY54|ensembl:ENSP00000356992	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:rhg30_human(display_long)|uniprotkb:ARHGAP30(gene name)|psi-mi:ARHGAP30(display_short)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Naji et al. (2011)	pubmed:21565175|imex:IM-28936	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26970993|imex:IM-28936-9	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	refseq:XP_011507693.1|refseq:NP_001020769.1|refseq:NP_859071.2|refseq:NP_001274529.1|refseq:NP_001274531.1|ensembl:ENSG00000186517(gene)|ensembl:ENST00000368013(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0031410"(cytoplasmic vesicle)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-HSA-8980692|reactome:R-HSA-9013148|reactome:R-HSA-9013149|reactome:R-HSA-9013420|go:"GO:0005829"(cytosol)|refseq:XP_005245130.1	-	-	-	figure legend:Fig. 1C|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/05/06	2021/05/06	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:L0Pbx3s9V/lw/NAiHZHnvXwI8Hw9606	rigid:7B6PwlB8b6Ym5j9Efv90qpbG1/k	false	flag tag:n-n	myc tag:n-n|necessary binding region:216-890	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7L0Q8	uniprotkb:A6X8Z5	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-4325995|uniprotkb:Q3TL91|uniprotkb:Q3U1T7|uniprotkb:Q3UDE7|uniprotkb:Q3UUH4|uniprotkb:Q6ZPW0|uniprotkb:Q9WV94|ensembl:ENSMUSP00000023487	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:rhg31_mouse(display_long)|uniprotkb:Arhgap31(gene name)|psi-mi:Arhgap31(display_short)|uniprotkb:Cdgap(gene name synonym)|uniprotkb:Kiaa1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Naji et al. (2011)	pubmed:21565175|imex:IM-28936	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26971159|imex:IM-28936-13	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	refseq:NP_064656.2|ensembl:ENSMUSG00000022799(gene)|ensembl:ENSMUST00000023487(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/05/06	2021/05/06	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:cke6zTbYFfVm5W0qMGbjV0IrqvM10090	rigid:CLBABhMHxbvdi0E+azS2RDDD25Y	false	flag tag:n-n|mutation disrupting interaction strength:63-63|mutation with no effect:107-107	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7L0Q8	uniprotkb:A6X8Z5	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-4325995|uniprotkb:Q3TL91|uniprotkb:Q3U1T7|uniprotkb:Q3UDE7|uniprotkb:Q3UUH4|uniprotkb:Q6ZPW0|uniprotkb:Q9WV94|ensembl:ENSMUSP00000023487	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:rhg31_mouse(display_long)|uniprotkb:Arhgap31(gene name)|psi-mi:Arhgap31(display_short)|uniprotkb:Cdgap(gene name synonym)|uniprotkb:Kiaa1204(gene name synonym)|uniprotkb:Cdc42 GTPase-activating protein(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Naji et al. (2011)	pubmed:21565175|imex:IM-28936	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:10090(mouse)|taxid:10090(Mus musculus)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26971179|imex:IM-28936-15	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	refseq:NP_064656.2|ensembl:ENSMUSG00000022799(gene)|ensembl:ENSMUST00000023487(transcript)|go:"GO:0005096"(GTPase activator activity)|go:"GO:0005925"(focal adhesion)|go:"GO:0007264"(small GTPase mediated signal transduction)|go:"GO:0017124"(SH3 domain binding)|go:"GO:0030027"(lamellipodium)|interpro:IPR000198(RhoGAP)|interpro:IPR008936(Rho GTPase activation protein)|reactome:R-MMU-8980692|reactome:R-MMU-9013148|reactome:R-MMU-9013149	-	-	-	figure legend:Fig. 4B|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9606(human-293t)|taxid:9606(Homo sapiens 293 cells transformed with SV40 large T antigen)	-	2021/05/06	2021/05/06	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:cke6zTbYFfVm5W0qMGbjV0IrqvM10090	rigid:CLBABhMHxbvdi0E+azS2RDDD25Y	false	flag tag:n-n|mutation disrupting interaction strength:63-63|mutation with no effect:107-107	myc tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)
uniprotkb:Q7L0Q8	uniprotkb:Q7Z6I6-2	intact:EBI-1638043|uniprotkb:B1AKN1|uniprotkb:Q59FE9|uniprotkb:Q8TDQ2|ensembl:ENSP00000355652|ensembl:ENSP00000494673	intact:EBI-26970905	psi-mi:rhou_human(display_long)|uniprotkb:RHOU(gene name)|psi-mi:RHOU(display_short)|uniprotkb:ARHU(gene name synonym)|uniprotkb:CDC42L1(gene name synonym)|uniprotkb:G28K(gene name synonym)|uniprotkb:WRCH1(gene name synonym)|uniprotkb:SB128(orf name)|uniprotkb:Wnt-1 responsive Cdc42 homolog 1(gene name synonym)|uniprotkb:Ryu GTPase(gene name synonym)|uniprotkb:CDC42-like GTPase 1(gene name synonym)|uniprotkb:Rho GTPase-like protein ARHU(gene name synonym)|uniprotkb:GTP-binding protein-like 1(gene name synonym)	psi-mi:q7z6i6-2(display_long)|uniprotkb:Rho-type GTPase-activating protein 30(gene name synonym)|uniprotkb:S-30(isoform synonym)|uniprotkb:S-ARHGAP30(isoform synonym)|uniprotkb:ARHGAP30(gene name)|psi-mi:ARHGAP30(display_short)	psi-mi:"MI:0416"(fluorescence microscopy)	Naji et al. (2011)	pubmed:21565175|imex:IM-28936	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0403"(colocalization)	psi-mi:"MI:0486"(UniProt)	intact:EBI-26971074|imex:IM-28936-11	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0497"(neutral component)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_067028.1|ensembl:ENSG00000116574(gene)|ensembl:ENST00000366691(transcript)|ensembl:ENST00000646945(transcript)|go:"GO:0000139"(Golgi membrane)|go:"GO:0002102"(podosome)|ensembl:ENSG00000284984(gene)|go:"GO:0003924"(GTPase activity)|go:"GO:0005085"(guanyl-nucleotide exchange factor activity)|go:"GO:0005525"(GTP binding)|go:"GO:0005829"(cytosol)|go:"GO:0005886"(plasma membrane)|go:"GO:0005925"(focal adhesion)|go:"GO:0006897"(endocytosis)|go:"GO:0007010"(cytoskeleton organization)|go:"GO:0008360"(regulation of cell shape)|go:"GO:0016477"(cell migration)|go:"GO:0030031"(cell projection assembly)|go:"GO:0032488"(Cdc42 protein signal transduction)|go:"GO:0042995"(cell projection)|go:"GO:0046872"(metal ion binding)|go:"GO:0051056"(regulation of small GTPase mediated signal transduction)|go:"GO:1903955"(positive regulation of protein targeting to mitochondrion)|interpro:IPR001806(Ras GTPase)|interpro:IPR003578(Ras small GTPase, Rho type)|interpro:IPR005225(Small GTP-binding protein)|interpro:IPR027417|mint:Q7L0Q8|rcsb pdb:2Q3H|reactome:R-HSA-6785807|reactome:R-HSA-9013420	intact:EBI-2814810(isoform-parent)	go:"GO:0031410"(cytoplasmic vesicle)	-	-	figure legend:Fig. 1E|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9823(pig-pae)|taxid:9823(Sus scrofa - procine aortic endothelial cells)	-	2021/05/06	2021/05/06	rogid:wrOPjo6G3FraKiREmUiUqoHYuEc9606	rogid:mFIzoN7LxL49XyY9zaJDjlZk0k89606	rigid:DQt7u9r11ExBY1m5UsTspmlWH30	false	myc tag:n-n|mutation decreasing interaction strength:83-83	flag tag:n-n	-	-	psi-mi:"MI:1201"(anti-tag immunocytochemistry)	psi-mi:"MI:1201"(anti-tag immunocytochemistry)