#ID(s) interactor A ID(s) interactor B Alt. ID(s) interactor A Alt. ID(s) interactor B Alias(es) interactor A Alias(es) interactor B Interaction detection method(s) Publication 1st author(s) Publication Identifier(s) Taxid interactor A Taxid interactor B Interaction type(s) Source database(s) Interaction identifier(s) Confidence value(s) Expansion method(s) Biological role(s) interactor A Biological role(s) interactor B Experimental role(s) interactor A Experimental role(s) interactor B Type(s) interactor A Type(s) interactor B Xref(s) interactor A Xref(s) interactor B Interaction Xref(s) Annotation(s) interactor A Annotation(s) interactor B Interaction annotation(s) Host organism(s) Interaction parameter(s) Creation date Update date Checksum(s) interactor A Checksum(s) interactor B Interaction Checksum(s) Negative Feature(s) interactor A Feature(s) interactor B Stoichiometry(s) interactor A Stoichiometry(s) interactor B Identification method participant A Identification method participant B uniprotkb:Q96QE5 uniprotkb:Q9NYK5 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-2513042|ensembl:ENSP00000284967|uniprotkb:Q9BZV6|uniprotkb:Q32Q74|uniprotkb:Q9BSQ7|uniprotkb:Q5QTR3|uniprotkb:Q96Q65|uniprotkb:Q9NX44|uniprotkb:C9JYA5 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rm39_human(display_long)|uniprotkb:MRPL39(gene name)|psi-mi:MRPL39(display_short)|uniprotkb:C21orf92(gene name synonym)|uniprotkb:MRPL5(gene name synonym)|uniprotkb:RPML5(gene name synonym)|uniprotkb:39S ribosomal protein L5, mitochondrial(gene name synonym)|uniprotkb:MSTP003(orf name)|uniprotkb:PRED22(orf name)|uniprotkb:Mitochondrial large ribosomal subunit protein mL39(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA ensembl:ENSG00000154719(gene)|ensembl:ENST00000352957(transcript)|go:"GO:0000166"(nucleotide binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|interpro:IPR004095(TGS)|interpro:IPR012675(Beta-grasp fold, ferredoxin-type)|interpro:IPR012676(TGS-like)|interpro:IPR018163|mint:Q9NYK5|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6NU3|refseq:NP_059142.2|refseq:NP_542984.2|refseq:XP_006724089.1 go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:yolHEKnYRC1KwprZYyWZXZmjgr89606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:Q9BYD1 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-1054936|uniprotkb:Q9UI04|uniprotkb:B2R4R8|ensembl:ENSP00000306548 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rm13_human(display_long)|uniprotkb:MRPL13(gene name)|psi-mi:MRPL13(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL13m(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_054797.2|ensembl:ENSG00000172172(gene)|ensembl:ENST00000306185(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003729"(mRNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0017148"(negative regulation of translation)|interpro:IPR005822(Ribosomal protein L13)|interpro:IPR005823(Ribosomal protein L13, bacterial-type)|interpro:IPR023563|interpro:IPR036899|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:7OF0 go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:Pw5ew6DULA24n90G2VmBHdhM4y49606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:Q9BYD3 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-721368|uniprotkb:A6NNV7|uniprotkb:Q9BW07|uniprotkb:Q9H4N2|uniprotkb:Q9Y317|ensembl:ENSP00000253099|ensembl:ENSP00000306902 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rm04_human(display_long)|uniprotkb:MRPL4(gene name)|psi-mi:MRPL4(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL4m(gene name synonym)|uniprotkb:CDABP0091(orf name)|uniprotkb:CGI-28(orf name) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_057040.2|refseq:NP_666499.1|refseq:NP_666500.1|ensembl:ENSG00000105364(gene)|ensembl:ENST00000253099(transcript)|ensembl:ENST00000307422(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|interpro:IPR002136(Ribosomal protein L4/L1e)|interpro:IPR013005(Ribosomal protein L4/L1e, bacterial-type)|interpro:IPR023574|mint:Q9BYD3|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20 go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:v1MODeAQQcG4MKCE/hvEg2NBwmk9606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:Q9Y3D9 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-1054270|uniprotkb:Q96Q24|uniprotkb:Q9BWH8|uniprotkb:Q9P053|uniprotkb:B2R6V3|ensembl:ENSP00000320184 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rt23_human(display_long)|uniprotkb:MRPS23(gene name)|psi-mi:MRPS23(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS23(gene name synonym)|uniprotkb:CGI-138(orf name)|uniprotkb:HSPC329(orf name) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_057154.2|ensembl:ENSG00000181610(gene)|ensembl:ENST00000313608(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005840"(ribosome)|go:"GO:0006412"(translation)|go:"GO:0031965"(nuclear membrane)|interpro:IPR019520|interpro:IPR023611|mint:Q9Y3D9|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:6Iyu6KkT1Y0+n0LKWy5Gf0DkhHw9606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:O15235 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-712205|ensembl:ENSP00000308845|ensembl:ENSP00000384579|ensembl:ENSP00000384952|ensembl:ENSP00000488926|ensembl:ENSP00000489374|ensembl:ENSP00000489467|uniprotkb:Q53X98 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rt12_human(display_long)|uniprotkb:MT-RPS12(gene name synonym)|uniprotkb:MRPS12(gene name)|psi-mi:MRPS12(display_short)|uniprotkb:RPMS12(gene name synonym)|uniprotkb:RPSM12(gene name synonym)|uniprotkb:Mitochondrial small ribosomal subunit protein uS12m(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA go:"GO:0006412"(translation)|go:"GO:0032543"(mitochondrial translation)|interpro:IPR005679(Ribosomal protein S12, bacterial-type)|interpro:IPR006032(Ribosomal protein S12/S23)|interpro:IPR012340(Nucleic acid-binding, OB-fold)|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|go:"GO:0005840"(ribosome)|ensembl:ENSG00000128626(gene)|ensembl:ENSG00000283018(gene)|ensembl:ENST00000308018(transcript)|ensembl:ENST00000402029(transcript)|ensembl:ENST00000407800(transcript)|ensembl:ENST00000634246(transcript)|ensembl:ENST00000634400(transcript)|ensembl:ENST00000634704(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005761"(mitochondrial ribosome)|go:"GO:0005763"(mitochondrial small ribosomal subunit)|refseq:NP_066930.1|refseq:NP_203526.1|refseq:NP_203527.1 go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:FDGNbJ2YFbUR4eQ3AyFtC8trETo9606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:Q9P015 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-2371967|uniprotkb:Q96Q54|uniprotkb:Q9H0Y1|ensembl:ENSP00000260102 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rm15_human(display_long)|uniprotkb:MRPL15(gene name)|psi-mi:MRPL15(display_short)|uniprotkb:Mitochondrial large ribosomal subunit protein uL15m(gene name synonym)|uniprotkb:HSPC145(orf name) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_054894.1|ensembl:ENSG00000137547(gene)|ensembl:ENST00000260102(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0003735"(structural constituent of ribosome)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005762"(mitochondrial large ribosomal subunit)|go:"GO:0006412"(translation)|go:"GO:1990830"(cellular response to leukemia inhibitory factor)|interpro:IPR005749(Ribosomal protein L15, bacterial-type)|interpro:IPR021131|interpro:IPR030878|interpro:IPR036227|mint:Q9P015|rcsb pdb:3J7Y|rcsb pdb:3J9M|rcsb pdb:5OOL|rcsb pdb:5OOM|rcsb pdb:6I9R|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSB|rcsb pdb:6ZSC|rcsb pdb:6ZSD|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5H|rcsb pdb:7A5I|rcsb pdb:7A5J|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7L20|rcsb pdb:7O9K|rcsb pdb:7O9M|rcsb pdb:7ODR|rcsb pdb:7ODS|rcsb pdb:7ODT|rcsb pdb:7OF0|rcsb pdb:7OF2|rcsb pdb:7OF3|rcsb pdb:7OF4|rcsb pdb:7OF5|rcsb pdb:7OF6|rcsb pdb:7OF7|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSA go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:efJei4RFNcTx2MqyMwdu7EXO1c09606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:Q7L2E3 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:Q96EY7 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:O00411 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124087|imex:IM-29354-1 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5B, Supp. table 2|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/26 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rigid:QeTTZNeEY3sRt6plbYlHitGw1LA false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0102"(sequence tag identification) psi-mi:"MI:0102"(sequence tag identification) uniprotkb:Q96QE5 uniprotkb:Q7L2E3 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-1211456|uniprotkb:O94965|uniprotkb:Q7Z753|uniprotkb:Q96CH4|uniprotkb:Q9NUQ0|uniprotkb:A8K5F1|ensembl:ENSP00000392601|ensembl:ENSP00000405620|intact:EBI-21350949 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:dhx30_human(display_long)|uniprotkb:DHX30(gene name)|psi-mi:DHX30(display_short)|uniprotkb:KIAA0890(gene name synonym)|uniprotkb:DDX30(gene name synonym)|uniprotkb:DEAH box protein 30(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124120|imex:IM-29354-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_055781.2|refseq:NP_619520.1|refseq:XP_011531796.1|refseq:XP_011531797.1|refseq:XP_016861406.1|ensembl:ENSG00000132153(gene)|go:"GO:0005524"(ATP binding)|go:"GO:0005737"(cytoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005829"(cytosol)|go:"GO:0007417"(central nervous system development)|go:"GO:0035770"(ribonucleoprotein granule)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0140603"(obsolete ATP hydrolysis activity)|go:"GO:1902775"(mitochondrial large ribosomal subunit assembly)|interpro:IPR001650(DNA/RNA helicase, C-terminal)|interpro:IPR002464(DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site)|interpro:IPR007502(Helicase-associated region)|interpro:IPR011545(DNA/RNA helicase, DEAD/DEAH box type, N-terminal)|interpro:IPR011709(Region of unknown function DUF1605)|interpro:IPR014001(DEAD-like helicase, N-terminal)|interpro:IPR027417|mint:Q7L2E3|rcsb pdb:2DB2|ensembl:ENST00000445061(transcript)|ensembl:ENST00000446256(transcript)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003724"(RNA helicase activity)|go:"GO:0003725"(double-stranded RNA binding) go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5C, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:tb4GzZKLycraXS0NlVqj8reV3IQ9606 rigid:DUInyHMQr3/OshdszybpZrXZxjM false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QE5 uniprotkb:Q96EY7 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124120|imex:IM-29354-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5C, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606 rigid:DUInyHMQr3/OshdszybpZrXZxjM false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QE5 uniprotkb:O00411 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124120|imex:IM-29354-3 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5C, 6B|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rigid:DUInyHMQr3/OshdszybpZrXZxjM false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O00411 uniprotkb:Q00059 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 intact:EBI-1049924|uniprotkb:Q5U0C6|uniprotkb:B5BU05|uniprotkb:A9QXC6|uniprotkb:A8MRB2|ensembl:ENSP00000420588 psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:tfam_human(display_long)|uniprotkb:TCF6(gene name synonym)|uniprotkb:Mitochondrial transcription factor 1(gene name synonym)|uniprotkb:Transcription factor 6-like 2(gene name synonym)|uniprotkb:TFAM(gene name)|psi-mi:TFAM(display_short)|uniprotkb:TCF6L2(gene name synonym)|uniprotkb:Transcription factor 6(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124135|imex:IM-29354-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N refseq:NP_003192.1|refseq:NP_001257711.1|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|go:"GO:0045893"(positive regulation of transcription, DNA-templated)|interpro:IPR009071(High mobility group box, HMG)|interpro:IPR036910|mint:Q00059|rcsb pdb:3FGH|rcsb pdb:3TMM|rcsb pdb:3TQ6|rcsb pdb:4NNU|rcsb pdb:4NOD|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:6HB4|rcsb pdb:6HC3|go:"GO:0033108"(mitochondrial respiratory chain complex assembly)|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0032991"(protein-containing complex)|ensembl:ENSG00000108064(gene)|ensembl:ENST00000487519(transcript)|go:"GO:0000976"(transcription cis-regulatory region binding)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0001223"(transcription coactivator binding)|go:"GO:0003682"(chromatin binding)|go:"GO:0003723"(RNA binding)|go:"GO:0005634"(nucleus)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0005829"(cytosol)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0008301"(DNA binding, bending)|go:"GO:0031072"(heat shock protein binding) go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5G-H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rogid:JqG4yJbWWsYMvex7a6GDIDxiVcs9606 rigid:yDmU+Cq28XBD11Jpn23CmhfxCcg false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O00411 uniprotkb:Q9H5Q4 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 intact:EBI-1043912|ensembl:ENSP00000355471|uniprotkb:Q9H626 psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:tfb2m_human(display_long)|uniprotkb:TFB2M(gene name)|psi-mi:TFB2M(display_short)|uniprotkb:NS5ATP5(gene name synonym)|uniprotkb:"S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 2"(gene name synonym)|uniprotkb:Mitochondrial 12S rRNA dimethylase 2(gene name synonym)|uniprotkb:Mitochondrial transcription factor B2(gene name synonym)|uniprotkb:Hepatitis C virus NS5A-transactivated protein 5(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124135|imex:IM-29354-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N refseq:NP_071761.1|ensembl:ENST00000366514(transcript)|go:"GO:0000179"("rRNA (adenine-N6,N6-)-dimethyltransferase activity")|go:"GO:0003712"(transcription coregulator activity)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006391"(transcription initiation from mitochondrial promoter)|go:"GO:0031167"(rRNA methylation)|go:"GO:0034246"(mitochondrial transcription factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|interpro:IPR001737(Ribosomal RNA adenine methylase transferase)|interpro:IPR016861(Mitochondrial dimethyladenosine transferase 2, mitochondrial precursor)|interpro:IPR020598|interpro:IPR029063|mint:Q9H5Q4|rcsb pdb:6ERO|rcsb pdb:6ERP|rcsb pdb:6ERQ|reactome:R-HSA-163282|reactome:R-HSA-2151201|ensembl:ENSG00000162851(gene)|dip:DIP-50540N go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5G-H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rogid:qg7FnDzaxjvzpH+KxQFk52NyvUI9606 rigid:yDmU+Cq28XBD11Jpn23CmhfxCcg false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:O00411 uniprotkb:Q96QE5 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124135|imex:IM-29354-5 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 5G-H|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rigid:yDmU+Cq28XBD11Jpn23CmhfxCcg false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QE5 uniprotkb:O00411 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124183|imex:IM-29354-9 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 6B|comment:Cells were pretreated with RNase A|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rigid:FOCYqDjnL2v/TGnL9RvOINs1wNw false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QE5 uniprotkb:Q96EY7 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-721110|uniprotkb:A6NHD2|uniprotkb:Q597H0|uniprotkb:Q658Y9|uniprotkb:Q9BUZ8|uniprotkb:Q9NWL0|intact:EBI-2560120|uniprotkb:D6W5M1|ensembl:ENSP00000254630 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:ptcd3_human(display_long)|uniprotkb:Transformation-related gene 15 protein(gene name synonym)|uniprotkb:TRG15(orf name)|uniprotkb:28S ribosomal protein S39, mitochondrial(gene name synonym)|uniprotkb:MRPS39(gene name synonym)|uniprotkb:PTCD3(gene name)|psi-mi:PTCD3(display_short)|uniprotkb:Mitochondrial small ribosomal subunit protein mS39(gene name synonym) psi-mi:"MI:0276"(blue native page) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124158|imex:IM-29354-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_060422.4|go:"GO:0032543"(mitochondrial translation)|go:"GO:0043024"(ribosomal small subunit binding)|interpro:IPR002885(Pentatricopeptide repeat)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR037387|mint:Q96EY7|rcsb pdb:3J9M|rcsb pdb:6NU2|rcsb pdb:6NU3|rcsb pdb:6RW4|rcsb pdb:6RW5|rcsb pdb:6VLZ|rcsb pdb:6VMI|rcsb pdb:6ZM5|rcsb pdb:6ZM6|rcsb pdb:6ZS9|rcsb pdb:6ZSA|rcsb pdb:6ZSB|go:"GO:0019843"(rRNA binding)|rcsb pdb:6ZSC|ensembl:ENSG00000132300(gene)|ensembl:ENST00000254630(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005739"(mitochondrion)|go:"GO:0005743"(mitochondrial inner membrane)|go:"GO:0005829"(cytosol)|go:"GO:0005840"(ribosome)|go:"GO:0005886"(plasma membrane)|go:"GO:0006417"(regulation of translation)|rcsb pdb:6ZSE|rcsb pdb:6ZSG|rcsb pdb:7A5F|rcsb pdb:7A5G|rcsb pdb:7A5I|rcsb pdb:7A5K|rcsb pdb:7L08|rcsb pdb:7OG4|reactome:R-HSA-5368286|reactome:R-HSA-5389840|reactome:R-HSA-5419276|rcsb pdb:6ZSD go:"GO:0005739"(mitochondrion) - - figure legend:SUpp. Fig. 4A|comment:Treatment of the mitochondrial lysate with RNase A, but not DNase I, disrupted the complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:k9hyBtBrNbiBMJ5gtOQ9R6Grl9U9606 rigid:XlF4bTh68/qOzn1iEOd6DkDAaiY false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QE5 uniprotkb:O00411 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:"MI:0276"(blue native page) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0914"(association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124158|imex:IM-29354-7 - psi-mi:"MI:1060"(spoke expansion) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N go:"GO:0005739"(mitochondrion) - - figure legend:SUpp. Fig. 4A|comment:Treatment of the mitochondrial lysate with RNase A, but not DNase I, disrupted the complex|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rigid:XlF4bTh68/qOzn1iEOd6DkDAaiY false strep ii tag:?-?|flag tag:?-? - - - psi-mi:"MI:0113"(western blot) psi-mi:"MI:0113"(western blot) uniprotkb:Q96QE5 uniprotkb:O00411 intact:EBI-725550|uniprotkb:Q6GPG5|uniprotkb:Q6PJ19|uniprotkb:Q96H04|uniprotkb:Q9H5Z9|uniprotkb:E1P655|ensembl:ENSP00000462963 intact:EBI-355145|uniprotkb:O60370|ensembl:ENSP00000465759 psi-mi:tefm_human(display_long)|uniprotkb:TEFM(gene name)|psi-mi:TEFM(display_short)|uniprotkb:C17orf42(gene name synonym) psi-mi:rpom_human(display_long)|uniprotkb:POLRMT(gene name)|psi-mi:POLRMT(display_short) psi-mi:"MI:0096"(pull down) Minczuk et al. (2011) pubmed:21278163|imex:IM-29354 taxid:9606(human)|taxid:9606(Homo sapiens) taxid:9606(human)|taxid:9606(Homo sapiens) psi-mi:"MI:0915"(physical association) psi-mi:"MI:0486"(UniProt) intact:EBI-27124201|imex:IM-29354-11 - - psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0499"(unspecified role) psi-mi:"MI:0496"(bait) psi-mi:"MI:0498"(prey) psi-mi:"MI:0326"(protein) psi-mi:"MI:0326"(protein) refseq:NP_078959.3|ensembl:ENSG00000172171(gene)|ensembl:ENST00000581216(transcript)|go:"GO:0003723"(RNA binding)|go:"GO:0005739"(mitochondrion)|go:"GO:0005759"(mitochondrial matrix)|go:"GO:0006119"(oxidative phosphorylation)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0006259"(DNA metabolic process)|go:"GO:0006392"(transcription elongation from mitochondrial promoter)|go:"GO:0030337"(DNA polymerase processivity factor activity)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:1990904"(ribonucleoprotein complex)|interpro:IPR010994(RuvA domain 2-like)|interpro:IPR012337(Polynucleotidyl transferase, Ribonuclease H fold)|interpro:IPR036397|interpro:IPR039150|rcsb pdb:5OL8|rcsb pdb:5OL9|rcsb pdb:5OLA refseq:NP_005026.3|ensembl:ENSG00000099821(gene)|ensembl:ENST00000588649(transcript)|go:"GO:0001018"(mitochondrial promoter sequence-specific DNA binding)|go:"GO:0003723"(RNA binding)|go:"GO:0003899"(DNA-directed 5'-3' RNA polymerase activity)|go:"GO:0005739"(mitochondrion)|go:"GO:0006390"(mitochondrial transcription)|go:"GO:0032991"(protein-containing complex)|go:"GO:0034245"(mitochondrial DNA-directed RNA polymerase complex)|go:"GO:0042645"(mitochondrial nucleoid)|go:"GO:0043565"(sequence-specific DNA binding)|interpro:IPR002092(DNA-directed RNA polymerase, bacteriophage type)|interpro:IPR011990(Tetratricopeptide-like helical)|interpro:IPR029262|interpro:IPR037159|interpro:IPR043502|rcsb pdb:3SPA|rcsb pdb:4BOC|rcsb pdb:5OLA|rcsb pdb:6ERP|rcsb pdb:6ERQ|rcsb pdb:7A8P|reactome:R-HSA-163282|reactome:R-HSA-2151201|go:"GO:0005759"(mitochondrial matrix)|dip:DIP-56412N go:"GO:0005739"(mitochondrion) - - figure legend:Fig. 7C|full coverage:Only protein-protein interactions|curation depth:imex curation taxid:9606(human-293 flp-in)|taxid:9606(Homo sapiens) - 2021/11/12 2021/11/15 rogid:J9SC0xwD2Y12yxNOohh3XyWkMu89606 rogid:88pltXGP9J+KpVZITuRCz2XRhHg9606 rigid:FOCYqDjnL2v/TGnL9RvOINs1wNw false strep ii tag:?-?|flag tag:?-? myc tag:c-c|sufficient binding region:768-1230 - - psi-mi:"MI:0705"(anti tag western blot) psi-mi:"MI:0705"(anti tag western blot)