#ID(s) interactor A	ID(s) interactor B	Alt. ID(s) interactor A	Alt. ID(s) interactor B	Alias(es) interactor A	Alias(es) interactor B	Interaction detection method(s)	Publication 1st author(s)	Publication Identifier(s)	Taxid interactor A	Taxid interactor B	Interaction type(s)	Source database(s)	Interaction identifier(s)	Confidence value(s)	Expansion method(s)	Biological role(s) interactor A	Biological role(s) interactor B	Experimental role(s) interactor A	Experimental role(s) interactor B	Type(s) interactor A	Type(s) interactor B	Xref(s) interactor A	Xref(s) interactor B	Interaction Xref(s)	Annotation(s) interactor A	Annotation(s) interactor B	Interaction annotation(s)	Host organism(s)	Interaction parameter(s)	Creation date	Update date	Checksum(s) interactor A	Checksum(s) interactor B	Interaction Checksum(s)	Negative	Feature(s) interactor A	Feature(s) interactor B	Stoichiometry(s) interactor A	Stoichiometry(s) interactor B	Identification method participant A	Identification method participant B
uniprotkb:O75161	uniprotkb:Q96KN7	intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0	intact:EBI-1050213|uniprotkb:Q7Z2W6|uniprotkb:Q8IXV5|uniprotkb:Q96QA8|uniprotkb:Q9HB94|uniprotkb:Q9HB95|uniprotkb:Q9HBK6|uniprotkb:Q9NR40|intact:EBI-28979141|ensembl:ENSP00000382895	psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym)	psi-mi:rpgr1_human(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:"MI:0018"(two hybrid)	Fernández-Martínez et al. (2011)	pubmed:21224891|imex:IM-29161	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27065542|imex:IM-29161-1	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1	refseq:NP_065099.3|ensembl:ENST00000382933|ensembl:ENSP00000372391|ensembl:ENSP00000382895|ensembl:ENSG00000092200(gene)|ensembl:ENST00000400017(transcript)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0050896"(response to stimulus)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031134|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|rcsb pdb:4QAM	-	-	-	figure legend:2|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:4932(yeasx)|taxid:4932("Saccharomyces cerevisiae (Baker's yeast)")	-	2021/08/13	2021/08/13	rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606	rogid:kPKjJC4b+zX86SnkVPoLyq7/SYA9606	rigid:Jy5X00BMfeIsVqzsi7xludJabOM	false	-	mutation increasing interaction strength:812-812|mutation decreasing interaction strength:837-837(rs373515194)|mutation decreasing interaction strength:838-838(rs772480252)|necessary binding region:891-1286(rs780587095)|mutation with no effect:589-589(rs34067949)|mutation decreasing interaction strength:598-598(rs74034910)|mutation decreasing interaction strength:635-635(rs200325360)|mutation with no effect:764-764(rs758652031)|mutation decreasing interaction strength:806-806(rs142796310)|sufficient binding region:587-935	-	-	psi-mi:"MI:0396"(predetermined participant)	psi-mi:"MI:0396"(predetermined participant)
uniprotkb:Q96KN7	uniprotkb:O75161	intact:EBI-1050213|uniprotkb:Q7Z2W6|uniprotkb:Q8IXV5|uniprotkb:Q96QA8|uniprotkb:Q9HB94|uniprotkb:Q9HB95|uniprotkb:Q9HBK6|uniprotkb:Q9NR40|intact:EBI-28979141|ensembl:ENSP00000382895	intact:EBI-4281852|ensembl:ENSP00000367398|uniprotkb:Q8IWC0	psi-mi:rpgr1_human(display_long)|uniprotkb:RPGRIP1(gene name)|psi-mi:RPGRIP1(display_short)	psi-mi:nphp4_human(display_long)|uniprotkb:NPHP4(gene name)|psi-mi:NPHP4(display_short)|uniprotkb:KIAA0673(gene name synonym)|uniprotkb:Nephroretinin(gene name synonym)	psi-mi:"MI:0007"(anti tag coimmunoprecipitation)	Fernández-Martínez et al. (2011)	pubmed:21224891|imex:IM-29161	taxid:9606(human)|taxid:9606(Homo sapiens)	taxid:9606(human)|taxid:9606(Homo sapiens)	psi-mi:"MI:0915"(physical association)	psi-mi:"MI:0469"(IntAct)	intact:EBI-27065740|imex:IM-29161-3	-	-	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0499"(unspecified role)	psi-mi:"MI:0498"(prey)	psi-mi:"MI:0496"(bait)	psi-mi:"MI:0326"(protein)	psi-mi:"MI:0326"(protein)	refseq:NP_065099.3|ensembl:ENST00000382933|ensembl:ENSP00000372391|ensembl:ENSP00000382895|ensembl:ENSG00000092200(gene)|ensembl:ENST00000400017(transcript)|go:"GO:0005930"(axoneme)|go:"GO:0007601"(visual perception)|go:"GO:0032391"(photoreceptor connecting cilium)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0046548"(retinal rod cell development)|go:"GO:0050896"(response to stimulus)|go:"GO:0061351"(neural precursor cell proliferation)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1905515"(non-motile cilium assembly)|interpro:IPR000008(C2 calcium-dependent membrane targeting)|interpro:IPR021656|interpro:IPR031134|interpro:IPR031139|interpro:IPR035892|interpro:IPR041091|rcsb pdb:4QAM	refseq:NP_001278522.1|refseq:NP_001278523.1|refseq:XP_011539518.1|refseq:XP_011539519.1|refseq:XP_011539520.1|ensembl:ENSG00000131697(gene)|ensembl:ENST00000378156(transcript)|go:"GO:0005198"(structural molecule activity)|go:"GO:0005654"(nucleoplasm)|go:"GO:0005813"(centrosome)|go:"GO:0005829"(cytosol)|go:"GO:0005911"(cell-cell junction)|go:"GO:0005923"(bicellular tight junction)|go:"GO:0007165"(signal transduction)|go:"GO:0007632"(visual behavior)|go:"GO:0016604"(nuclear body)|go:"GO:0030036"(actin cytoskeleton organization)|go:"GO:0030317"(flagellated sperm motility)|go:"GO:0035845"(photoreceptor cell outer segment organization)|go:"GO:0035869"(ciliary transition zone)|go:"GO:0036064"(ciliary basal body)|go:"GO:0043231"(intracellular membrane-bounded organelle)|go:"GO:0045494"(photoreceptor cell maintenance)|go:"GO:0060041"(retina development in camera-type eye)|go:"GO:0090090"(negative regulation of canonical Wnt signaling pathway)|go:"GO:0097470"(ribbon synapse)|go:"GO:0097546"(ciliary base)|go:"GO:0098609"(cell-cell adhesion)|go:"GO:0120206"(photoreceptor distal connecting cilium)|go:"GO:1903348"(positive regulation of bicellular tight junction assembly)|go:"GO:1904491"(protein localization to ciliary transition zone)|interpro:IPR029775|reactome:R-HSA-2028269|reactome:R-HSA-5620912|go:"GO:0097730"(non-motile cilium)|refseq:NP_055917.1|refseq:XP_006710626.1|refseq:XP_016856486.1	-	-	-	figure legend:3|dataset:Rare diseases - Interactions investigated in the context of Rare genetic disease|full coverage:Only protein-protein interactions|curation depth:imex curation	taxid:9534(chlae-cos_1)|taxid:9534(Chlorocebus aethiops COS-1 cells)	-	2021/08/13	2021/08/16	rogid:kPKjJC4b+zX86SnkVPoLyq7/SYA9606	rogid:oQi0NY0QgJtrAUUHvnob6BEKcIs9606	rigid:Jy5X00BMfeIsVqzsi7xludJabOM	false	flag tag:n-n|sufficient binding region:587-935|mutation disrupting interaction strength:598-598(rs74034910)	ha tag:n-n	-	-	psi-mi:"MI:0705"(anti tag western blot)	psi-mi:"MI:0705"(anti tag western blot)